≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback
info icon

This is a non-core endpoint: only basic statistics are computed.

Chondrosarcoma

EFO Endpoint Browser

C3_CHONDROSARCOMA

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C40.2|C4104|C4106|C4114|C4122|C4132|C4142|C4182|C4192
  • Cancer registry: Topography ICD-O-3 — ANY
  • Cancer registry: Morphology ICD-O-3 — 9220|9230|9231
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

105

4. Check minimum number of events

None

105

5. Include endpoints

None

105

6. Filter based on genotype QC (FinnGen only)

103

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 103 45 58
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 55.82 54.39 56.93

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
105
Matched controls
1050
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
118.5
31.9
33
*
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
+∞
29.6
27
*
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
27.3
25
*
130
Kela drug reimbursment
Malignant tumour
+∞
21.6
20
*
WX408
NOMESCO Finland
General anesthesy, balanced
6.6
21.1
53
140
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
17.1
16
*
C41.32
ICD-10 Finland
Chondrosarcoma of the ribs, sternum and clavicle
+∞
17.1
16
*
9220/3-C41.3
ICD-O-3
Chondrosarcoma, NOS, of rib, sternum, clavicle and associated joints
+∞
16.0
15
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
+∞
13.8
13
*
C41.82
ICD-10 Finland
Overall chondrosarcoma in bone and articular cartilage
+∞
12.8
12
*
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
12.8
12
*
XX3DW
NOMESCO Finland
Time consuming IT work
12.7
11.4
20
19
WX402
NOMESCO Finland
General anaesthesia
4.7
11.3
34
98
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
11.1
11.2
21
23
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
67.0
10.9
12
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
12.6
10.8
19
18
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
+∞
10.6
10
*
9220/3-C41.4
ICD-O-3
Chondrosarcoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
10.6
10
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.9
10.4
67
328
ZXE30
NOMESCO Finland
More than five and less than seven hours
19.2
10.2
15
9
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
60.8
9.8
11
*
H02AB02
ATC
dexamethasone; systemic
33.5
9.6
12
*
C32.3
ICD-10 Finland
Malignant neoplasm: Laryngeal cartilage
+∞
9.5
9
*
C41.42
ICD-10 Finland
Chondrosarcoma of the pelvic bones, sacrum and coccyx
+∞
9.5
9
*
9220/3-C40.0
ICD-O-3
Chondrosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
9.5
9
*
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
+∞
9.5
9
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
17.7
9.3
14
9
B01AB05
ATC
enoxaparin; parenteral
3.5
9.0
47
197
WF002
NOMESCO Finland
Radical radiotherapy
97.6
8.5
9
*
9220/3-C41.0
ICD-O-3
Chondrosarcoma, NOS, of bones of skull and face and associated joints
+∞
8.4
8
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
8.4
8
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
8.4
8
*
C41.3
ICD-10 Finland
Malignant neoplasm: Ribs, sternum and clavicle
+∞
8.4
8
*
JN4BD
NOMESCO Finland
Extensive body CT
7.8
8.4
19
29
A03FA01
ATC
metoclopramide; systemic, rectal
4.4
8.3
24
66
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.9
8.2
30
98
R4110
NOMESCO Finland
Physiotherapy
3.4
8.2
44
186
GBB00
NOMESCO Finland
Tracheostomy
27.3
7.7
10
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
27.3
7.7
10
*
ZXE10
NOMESCO Finland
More than one and less than three hours
3.2
7.7
49
227
ZXE20
NOMESCO Finland
More than three and less than five hours
4.1
7.7
25
75
B01AB10
ATC
tinzaparin; parenteral
6.8
7.7
19
33
TPH07
NOMESCO Finland
Cathetrisation of artery
4.3
7.7
23
65
L03AA13
ATC
pegfilgrastim; parenteral
85.9
7.5
8
*
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
85.9
7.5
8
*
A04AA02
ATC
granisetron; systemic, transdermal
85.9
7.5
8
*
NER30
NOMESCO Finland
Extended excision of soft tissue tumour of pelvis
+∞
7.4
7
*
9220/3-C32.3
ICD-O-3
Chondrosarcoma, NOS, of laryngeal cartilage
+∞
7.4
7
*
C41.22
ICD-10 Finland
Chondrosarcoma of the spine
+∞
7.4
7
*
C41.06
ICD-10 Finland
Chondrosarcoma of the skull or facial bones except maxilla
+∞
7.4
7
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
7.4
7
*
DQB20
NOMESCO Finland
Partial excision of larynx
+∞
7.4
7
*
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
7.4
7
*
GAE23
NOMESCO Finland
Resection of chest wall and prosthetic repair
+∞
7.4
7
*
WZC30
NOMESCO Finland
Teaching
4.0
7.0
23
69
NF3AA
NOMESCO Finland
Femur X-ray examination
10.4
7.0
13
14
JN4AD
NOMESCO Finland
Body CT examination
7.8
6.8
15
22
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
74.2
6.5
7
*
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
74.2
6.5
7
*
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
74.2
6.5
7
*
ZXB10
NOMESCO Finland
Medial
74.2
6.5
7
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
74.2
6.5
7
*
NG4AA
NOMESCO Finland
Lower leg X-ray examination
12.1
6.5
11
10
ZXE40
NOMESCO Finland
More than seven and less than nine hours
28.6
6.3
8
*
UDQ22
NOMESCO Finland
Microlaryngoscopy
28.6
6.3
8
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
6.3
6
*
C40.00
ICD-10 Finland
Malignant tumor of the scapula and the long bones of the upper extremity without histology
+∞
6.3
6
*
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
6.3
6
*
DQD50
NOMESCO Finland
Endoscopic insertion of stent in larynx
+∞
6.3
6
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
6.3
6
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
60
246
4.36
12.70
2.7
1.5
—
—
—
0
0
18
20
10.61
9.49
1.2
1.4
—
—
—
0
0
54
241
3.55
9.42
2.7
2.1
—
—
—
0
0
18
39
5.36
8.23
2.1
1.9
1.88
3.14
ug/l
1.62
13
27
20
54
4.34
7.03
1.4
1.1
—
—
—
0
0
25
87
3.46
6.13
6.2
7.4
0.46
1.48
mmol/l
0.99
20
72
15
47
3.56
4.24
8.1
9.9
1.20
1.49
%
0.79
15
47
15
47
3.56
4.24
8.5
9.9
0.89
0.76
%
0.47
15
47
66
447
2.28
3.99
7.1
6.4
4.85
4.34
e9/l
0.19
57
392
62
414
2.22
3.82
4.1
5.4
1.81
1.83
e9/l
0.07
50
373
55
352
2.18
3.75
4.9
5.5
1.20
1.21
mmol/l
1.04
48
319
62
417
2.19
3.72
3.8
5.5
0.23
0.20
e9/l
0.32
49
372
55
356
2.14
3.60
4.5
5.4
0.63
0.68
%
0.30
49
331
60
402
2.15
3.59
3.9
5.4
0.56
0.58
e9/l
0.24
48
358
60
403
2.14
3.56
3.9
5.4
0.04
0.04
e9/l
0.28
48
356
34
184
2.25
3.46
5.9
4.5
—
—
—
0
0
56
371
2.09
3.39
4.5
5.4
2.78
3.08
%
0.45
50
349
21
92
2.60
3.37
1.8
1.8
—
—
—
0
0
57
381
2.09
3.36
4.7
5.5
24.49
27.30
%
1.04
51
359
56
373
2.07
3.32
4.7
5.7
8.58
8.47
%
0.09
50
350
8
15
5.67
3.26
1.0
1.1
—
—
—
0
0
56
387
1.96
2.87
5.6
6.2
1.20
1.21
mmol/l
0.63
48
345
55
380
1.94
2.80
4.7
5.3
59.92
58.06
%
0.48
49
358
67
495
1.98
2.80
5.1
4.3
6.49
6.79
mmol/l
0.64
60
459
7
14
5.27
2.78
1.3
1.4
—
—
—
0
0
12
41
3.17
2.73
4.0
8.7
—
—
—
0
0
49
332
1.89
2.59
7.8
8.5
0.00
0.00
e9/l
0.40
34
274
11
39
3.03
2.43
8.1
9.0
24.05
24.83
mmol/l
0.42
11
39
14
59
2.58
2.41
9.2
9.2
—
—
—
0
0
5
9
5.77
2.24
2.8
5.3
71.20
59.67
%
—
5
9
55
401
1.78
2.20
13.2
14.1
1.29
1.33
inr
0.10
13
105
34
214
1.87
2.20
4.9
4.1
—
—
—
0
0
50
367
1.69
1.87
5.1
5.9
—
—
—
0
0
17
91
2.04
1.73
1.5
1.9
4.29
5.94
umol/l
1.44
17
80
18
99
1.99
1.70
2.2
6.4
0.98
1.05
mmol/l
0.52
18
93
30
196
1.74
1.68
1.5
1.3
—
—
—
0
0
11
53
2.20
1.44
6.5
3.0
—
—
—
0
0
11
53
2.20
1.44
2.7
5.1
—
—
—
0
0
64
525
1.56
1.38
4.3
4.4
—
920.60
—
0
10
14
76
1.97
1.37
1.9
1.3
—
—
—
0
0
0
38
0.00
1.37
0.0
1.1
—
—
—
0
0
5
17
3.03
1.37
1.2
1.1
—
—
—
0
0
92
827
1.91
1.36
17.7
12.7
31.11
23.90
mg/l
1.28
80
624
19
119
1.73
1.22
2.2
2.4
0.82
0.83
mmol/l
0.23
19
113
17
103
1.78
1.22
4.8
6.3
103.59
104.20
mmol/l
0.19
17
103
0
36
0.00
1.16
0.0
2.9
—
0.20
—
0
12
8
40
2.08
1.15
2.3
4.7
—
—
—
0
0
70
603
1.48
1.07
3.4
3.9
—
—
—
0
0
71
794
0.67
1.04
6.0
6.4
39.05
40.94
mmol/mol
0.84
61
739
18
118
1.63
0.99
2.1
1.7
—
—
—
0
0
30
223
1.48
0.97
1.8
3.3
7.41
7.40
ph
—
5
27
95
886
1.76
0.89
22.0
14.8
74.38
82.54
umol/l
2.39
95
886
94
875
1.71
0.88
20.6
15.4
3.93
4.00
mmol/l
1.69
89
846
94
876
1.70
0.86
17.5
11.9
—
—
—
0
0
79
857
0.68
0.84
4.4
5.3
2.46
2.66
mmol/l
1.37
66
793
10
161
0.58
0.84
1.3
1.4
1.92
2.64
g/l
—
5
93
77
838
0.70
0.82
4.0
4.8
4.37
4.53
mmol/l
0.68
66
780
77
834
0.71
0.74
4.2
4.8
1.47
1.45
mmol/l
0.20
65
772
9
57
1.63
0.73
1.3
2.2
0.19
0.22
g/l
—
9
51
98
930
1.81
0.72
26.8
18.5
38.94
40.72
%
1.99
90
865
98
930
1.81
0.72
26.6
18.5
7.51
6.65
e9/l
0.46
93
902
98
930
1.81
0.72
26.6
18.5
4.37
4.54
e12/l
1.96
93
900
22
287
0.70
0.71
2.6
3.2
6.74
7.46
mmol/l
0.54
15
241
30
238
1.36
0.67
3.3
3.3
—
—
—
0
0
23
295
0.72
0.67
3.3
4.0
1.61
10.96
mg/mmol
—
10
181
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
77
826
0.75
0.59
4.1
4.7
5.79
6.04
mmol/l
1.18
63
747
26
207
1.34
0.57
5.8
4.0
0.00
0.00
estimate
-0.00
12
58
22
277
0.74
0.56
2.7
3.3
10.50
78.09
mg/l
—
10
178
14
103
1.41
0.48
1.5
1.4
—
—
—
0
0
8
55
1.49
0.44
1.0
1.4
—
—
—
0
0
5
32
1.59
0.43
4.0
5.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.3
—
71.96
—
0
16
8
60
1.36
0.41
1.4
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.8
—
4.04
—
0
18
0
18
0.00
0.40
0.0
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.8
—
105.17
—
0
18
76
804
0.80
0.40
3.6
4.3
1.13
1.28
mmol/l
1.79
65
742
0
19
0.00
0.39
0.0
2.2
—
—
—
0
0
0
19
0.00
0.39
0.0
3.3
—
—
—
0
0
9
125
0.69
0.37
1.1
1.1
—
—
—
0
0
60
552
1.20
0.37
4.5
4.3
—
—
—
0
0
80
761
1.22
0.32
4.7
4.3
1.98
1.92
mu/l
0.16
68
687
8
106
0.73
0.31
1.1
1.4
—
382.50
—
0
32
8
65
1.25
0.28
1.3
1.2
—
—
—
0
0
24
208
1.20
0.27
2.5
2.9
0.37
0.40
e6/l
0.07
18
147
23
199
1.20
0.26
2.5
2.7
—
—
—
0
0
11
87
1.30
0.25
2.3
4.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
372.73
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
3.8
—
1.18
—
0
12
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
15
174
0.84
0.19
1.1
1.3
1.48
1.28
u/ml
—
5
52
8
69
1.17
0.17
3.1
3.7
—
—
—
0
0
26
237
1.13
0.16
2.4
3.0
36.67
301.17
e6/l
0.47
19
179
9
80
1.14
0.15
1.6
1.5
—
—
—
0
0
39
369
1.09
0.12
1.9
2.0
89.55
93.32
pmol/l
0.18
21
178
29
271
1.10
0.11
2.6
3.8
11.79
78.01
e6/l
1.09
20
189
5
47
1.07
0.09
2.4
2.2
—
—
—
0
0
5
48
1.04
0.09
1.2
1.6
—
—
—
0
0
21
197
1.08
0.07
2.6
2.6
1.16
0.75
ug/l
0.91
16
120
19
179
1.08
0.05
4.4
3.8
—
—
—
0
0
12
112
1.08
0.03
2.0
1.6
—
—
—
0
0
40
392
1.03
0.02
4.9
3.9
0.00
0.00
estimate
-0.00
12
66
17
177
0.95
0.01
1.5
1.7
1439.20
1201.61
nmol/l
—
10
131
34
347
0.97
0.01
4.2
3.9
27.92
47.87
ng/l
0.83
26
247
23
224
1.03
0.00
4.8
3.6
—
—
—
0
0
29
296
0.97
0.00
2.2
3.0
—
—
—
0
0
26
262
0.99
0.00
4.5
4.1
—
—
—
0
0
40
403
0.99
0.00
4.9
3.9
0.00
0.00
estimate
-0.00
11
55
40
397
1.01
0.00
5.8
5.4
0.00
0.00
estimate
-0.00
11
58
60
604
0.98
0.00
4.3
3.6
14.25
14.95
pmol/l
1.27
52
543
0
8
0.00
0.00
0.0
2.0
—
13.08
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
28.11
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
153.80
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
0.31
—
0
7
7
72
0.97
-0.00
1.4
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
85.47
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
6.21
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
82.20
—
0
5
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
1.95
—
0
7
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
738.80
—
0
5
7
79
0.88
-0.00
1.6
4.1
433.29
205.74
ng/l
—
7
70
8
85
0.94
-0.00
1.3
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
8
81
0.99
-0.00
2.6
1.6
318.38
371.89
nmol/l
—
8
73
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
213.83
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_CHONDROSARCOMA – Chondrosarcoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).