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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_CHONDROSARCOMA_EXALLC for full statistics.

Chondrosarcoma

C3_CHONDROSARCOMA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C40.2|C4104|C4106|C4114|C4122|C4132|C4142|C4182|C4192
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9220|9230|9231
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

103

4. Check minimum number of events

None

103

5. Include endpoints

None

103

6. Filter based on genotype QC (FinnGen only)

103

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 103 45 58
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 55.82 54.39 56.93

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
94
Matched controls
937
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
58.8
25.4
29
7
C40.22
ICD-10 Finland
Chondrosarcoma of the long bones of the lower extremity
+∞
25.1
23
*
9220/3-C40.2
ICD-O-3
Chondrosarcoma, NOS, of long bones of lower limb and associated joints
+∞
24.0
22
*
C40.20
ICD-10 Finland
Malignant tumor of the long bones of the lower extremity without histology
+∞
16.1
15
*
9220/3-C41.3
ICD-O-3
Chondrosarcoma, NOS, of rib, sternum, clavicle and associated joints
+∞
15.0
14
*
C41.32
ICD-10 Finland
Chondrosarcoma of the ribs, sternum and clavicle
+∞
15.0
14
*
C40.02
ICD-10 Finland
Chondrosarcoma of the scapula and long bones of the upper extremity
+∞
13.9
13
*
WX408
NOMESCO Finland
General anesthesy, balanced
5.2
12.0
47
151
C41.82
ICD-10 Finland
Overall chondrosarcoma in bone and articular cartilage
+∞
11.7
11
*
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
+∞
11.7
11
*
GAE06
NOMESCO Finland
Excision of lesion of chest wall
123.2
10.7
11
*
9220/3-C40.0
ICD-O-3
Chondrosarcoma, NOS, of long bones of upper limb, scapula and associated joints
+∞
10.6
10
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.1
9.6
61
294
9220/3-C41.4
ICD-O-3
Chondrosarcoma, NOS, of pelvic bones, sacrum, coccyx and associated joints
+∞
9.5
9
*
NK6BN
NOMESCO Finland
Bone dynamic isotope examination
98.5
8.6
9
*
NF3AA
NOMESCO Finland
Femur X-ray examination
36.9
8.3
10
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
8.4
7.9
17
24
C32.3
ICD-10 Finland
Malignant neoplasm: Laryngeal cartilage
+∞
7.4
7
*
C41.42
ICD-10 Finland
Chondrosarcoma of the pelvic bones, sacrum and coccyx
+∞
7.4
7
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
+∞
7.4
7
*
GAE23
NOMESCO Finland
Resection of chest wall and prosthetic repair
+∞
7.4
7
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
6.3
6.9
18
34
GBB00
NOMESCO Finland
Tracheostomy
43.3
6.9
8
*
NFR30
NOMESCO Finland
Extended excision of soft tissue tumour of hip or thigh
43.3
6.9
8
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
24.6
6.8
9
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
5.2
6.8
21
49
B01AB05
ATC
enoxaparin; parenteral
3.2
6.6
43
194
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
74.7
6.5
7
*
NGR20
NOMESCO Finland
Intralesional or marginal excision of tumor of knee or lower leg
74.7
6.5
7
*
C41.22
ICD-10 Finland
Chondrosarcoma of the spine
+∞
6.3
6
*
9220/3-C41.0
ICD-O-3
Chondrosarcoma, NOS, of bones of skull and face and associated joints
+∞
6.3
6
*
17071
ICD-8 Finland
Malignant neoplasm of bone, Lower limb, long bones
+∞
6.3
6
*
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
+∞
6.3
6
*
C40.00
ICD-10 Finland
Malignant tumor of the scapula and the long bones of the upper extremity without histology
+∞
6.3
6
*
C40.2
ICD-10 Finland
Malignant neoplasm: Long bones of lower limb
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
52
273
2.83
6.28
2.8
2.7
—
—
—
0
0
58
342
2.59
5.31
2.7
2.1
—
—
—
0
0
24
102
2.76
4.12
6.3
6.3
0.5
1.3
mmol/l
0.61
19
81
21
96
2.49
3.09
1.8
1.7
—
—
—
0
0
60
430
1.95
2.74
3.9
6.1
1.8
1.8
e9/l
0.12
49
394
42
267
1.97
2.73
4.1
5.6
—
—
—
0
0
53
366
1.92
2.69
7.7
9.1
1.2
1.2
inr
—
10
108
12
44
2.96
2.65
4.0
7.0
—
—
—
0
0
7
15
4.92
2.64
1.3
1.5
—
—
—
0
0
60
435
1.91
2.60
4.0
6.2
0.2
0.2
e9/l
0.07
49
400
58
420
1.87
2.48
3.9
6.0
0.6
0.6
e9/l
0.26
48
380
54
384
1.85
2.43
5.5
6.1
1.2
1.2
mmol/l
0.77
48
349
58
422
1.86
2.43
3.9
6.1
0.0
0.0
e9/l
0.42
48
383
53
375
1.85
2.42
4.2
5.9
0.6
0.6
%
0.10
48
354
55
397
1.83
2.33
4.4
6.2
25.0
26.9
%
0.57
49
375
54
389
1.82
2.29
4.3
5.9
2.8
2.7
%
0.07
49
369
54
391
1.80
2.24
4.5
6.2
8.7
8.6
%
0.09
49
371
34
217
1.85
2.10
7.6
7.4
—
—
—
0
0
17
84
2.23
2.10
1.2
1.3
—
—
—
0
0
7
21
3.50
2.00
1.0
1.3
—
—
—
0
0
20
108
2.06
1.99
1.4
1.2
—
—
—
0
0
64
499
1.75
1.96
7.3
10.0
3.8
4.3
e9/l
1.25
57
451
53
395
1.70
1.89
4.5
6.0
59.4
58.4
%
0.20
47
375
18
96
2.06
1.85
2.1
4.6
1.9
124.9
ug/l
0.88
13
81
0
49
0.00
1.74
0.0
1.2
—
—
—
0
0
65
525
1.65
1.61
5.1
4.6
6.5
6.7
mmol/l
0.47
58
485
18
102
1.93
1.57
2.1
2.7
4.2
7.2
umol/l
1.55
18
87
13
65
2.14
1.56
9.6
7.8
—
—
—
0
0
47
353
1.61
1.55
7.0
11.1
0.0
0.0
e9/l
0.71
34
303
68
784
0.61
1.49
6.3
6.3
39.3
41.0
mmol/mol
0.67
58
731
10
48
2.20
1.32
8.5
6.3
24.1
24.5
mmol/l
—
10
48
19
119
1.73
1.22
2.3
5.7
1.0
1.0
mmol/l
0.38
19
111
91
827
1.86
1.20
18.0
15.5
31.3
24.6
mg/l
1.12
79
662
5
20
2.57
1.16
1.2
1.3
—
—
—
0
0
0
36
0.00
1.16
0.0
3.4
—
0.2
—
0
11
8
41
2.03
1.11
2.3
3.4
—
—
—
0
0
5
22
2.34
1.04
1.8
1.1
353.8
3.4
e6/l
—
5
17
5
22
2.34
1.04
1.8
1.3
351.8
497.4
e6/l
—
5
17
11
62
1.87
0.98
2.7
3.9
—
—
—
0
0
69
605
1.43
0.89
3.3
4.1
—
—
—
0
0
63
548
1.39
0.83
4.3
4.8
—
437.8
—
0
11
34
268
1.40
0.80
5.0
4.6
—
—
—
0
0
0
24
0.00
0.80
0.0
1.5
—
—
—
0
0
27
206
1.42
0.76
1.4
1.3
—
—
—
0
0
11
162
0.64
0.65
1.3
1.6
1.7
2.7
g/l
—
6
106
78
836
0.72
0.64
4.4
5.3
2.5
2.6
mmol/l
1.26
65
759
76
817
0.73
0.63
4.0
4.7
4.4
4.5
mmol/l
0.81
65
748
8
52
1.58
0.61
1.3
1.3
—
—
—
0
0
92
871
1.53
0.60
17.1
14.2
—
—
—
0
0
92
873
1.50
0.56
21.0
17.7
3.9
4.0
mmol/l
1.13
87
843
6
37
1.66
0.56
2.0
4.3
22.1
254.8
mg/l
—
6
29
75
804
0.75
0.56
4.3
4.9
5.8
6.0
mmol/l
0.90
62
729
76
813
0.75
0.56
4.2
4.7
1.5
1.5
mmol/l
0.07
64
739
18
136
1.39
0.54
2.1
1.8
—
—
—
0
0
96
922
1.61
0.52
26.5
22.6
4.4
4.5
e12/l
0.88
91
896
96
922
1.61
0.52
26.5
22.6
6.6
6.8
e9/l
0.30
91
896
93
889
1.48
0.49
22.2
18.3
74.8
81.1
umol/l
1.72
93
889
13
94
1.44
0.49
1.5
1.4
—
—
—
0
0
9
126
0.69
0.47
1.1
1.3
—
—
—
0
0
19
149
1.34
0.46
2.2
3.4
0.8
0.8
mmol/l
0.08
19
142
77
720
1.28
0.44
21.6
15.7
37.7
40.2
%
1.68
54
514
8
56
1.46
0.44
1.0
1.3
—
—
—
0
0
10
70
1.47
0.43
6.4
3.8
—
—
—
0
0
22
267
0.78
0.43
2.6
3.1
6.7
7.7
mmol/l
0.78
15
224
16
202
0.75
0.42
2.9
6.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.5
—
30.3
—
0
12
0
17
0.00
0.41
0.0
1.8
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
30
257
1.24
0.38
2.8
4.5
7.4
7.4
ph
—
5
49
23
271
0.81
0.35
3.4
4.2
1.6
8.9
mg/mmol
—
10
161
30
261
1.21
0.33
3.2
3.1
—
—
—
0
0
22
257
0.82
0.31
2.7
3.3
10.5
61.0
mg/l
—
10
158
14
112
1.29
0.30
1.5
1.4
—
—
—
0
0
75
786
0.83
0.30
3.6
4.2
1.1
1.3
mmol/l
1.72
64
714
60
561
1.17
0.28
4.4
4.3
—
—
—
0
0
8
65
1.25
0.28
3.1
4.2
—
—
—
0
0
5
70
0.70
0.27
2.2
4.9
1.2
1.2
mmol/l
—
5
64
11
87
1.30
0.25
2.3
5.0
—
—
—
0
0
5
37
1.37
0.24
2.2
4.4
17.6
30.0
mg/l
—
5
29
5
38
1.33
0.23
2.4
2.4
—
—
—
0
0
5
40
1.26
0.23
4.0
4.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
61.2
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
3.2
—
4.0
—
0
12
0
12
0.00
0.21
0.0
3.3
—
—
—
0
0
0
12
0.00
0.21
0.0
3.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
3.3
—
107.3
—
0
12
0
13
0.00
0.21
0.0
2.6
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
87.8
—
0
14
39
360
1.13
0.20
1.8
2.0
88.4
92.9
pmol/l
0.21
20
178
27
296
0.88
0.17
2.2
3.0
—
—
—
0
0
16
182
0.86
0.17
1.4
1.7
1257.9
1256.1
nmol/l
—
9
137
28
305
0.89
0.16
2.5
4.0
8.0
78.7
e6/l
1.45
19
225
8
72
1.12
0.16
2.3
2.8
—
—
—
0
0
6
75
0.79
0.16
3.2
3.5
—
—
—
0
0
30
325
0.89
0.16
4.6
3.8
—
—
—
0
0
9
80
1.14
0.15
2.2
2.9
64.4
66.1
g/l
—
9
69
25
273
0.89
0.15
2.3
3.3
35.1
259.5
e6/l
0.48
18
216
25
228
1.13
0.15
5.8
4.4
0.0
0.0
estimate
0.00
11
80
20
180
1.14
0.14
4.3
4.1
—
—
—
0
0
8
97
0.81
0.14
1.1
1.5
—
425.6
—
0
25
78
758
1.12
0.14
4.7
4.5
2.0
2.0
mu/l
0.14
66
674
15
169
0.87
0.14
1.1
1.3
1.5
1.1
u/ml
—
5
49
22
240
0.89
0.13
4.7
3.4
—
—
—
0
0
33
348
0.92
0.09
4.0
4.2
27.5
50.9
ng/l
0.77
25
257
7
64
1.10
0.08
1.6
2.0
433.3
144.7
ng/l
—
7
54
22
234
0.92
0.07
2.4
3.1
—
—
—
0
0
9
101
0.88
0.06
1.2
1.5
—
—
—
0
0
25
263
0.93
0.06
4.4
4.6
—
—
—
0
0
40
413
0.95
0.05
4.8
3.9
0.0
0.0
estimate
—
10
80
40
411
0.96
0.04
5.7
5.2
0.0
0.0
estimate
—
10
82
23
240
0.95
0.04
2.3
3.1
0.3
0.5
e6/l
0.53
17
183
13
122
1.08
0.03
1.9
1.6
—
—
—
0
0
21
218
0.95
0.02
2.6
2.9
1.2
0.8
ug/l
0.91
16
147
10
93
1.08
0.02
1.5
1.5
—
—
—
0
0
40
407
0.97
0.01
4.8
3.9
0.0
0.0
estimate
0.00
11
87
59
592
0.99
0.00
4.4
3.9
14.2
14.9
pmol/l
1.17
51
527
0
7
0.00
0.00
0.0
1.3
—
7.3
—
0
7
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
25.1
—
0
5
0
9
0.00
0.00
0.0
2.0
—
0.5
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
8
87
0.91
0.00
2.6
2.2
318.4
379.0
nmol/l
—
8
79
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
240.7
—
0
6
0
9
0.00
0.00
0.0
1.9
—
2.4
—
0
9
7
70
1.00
0.00
1.4
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
2.1
—
0
5
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
64
0.93
0.00
1.2
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
8
87
0.91
0.00
1.4
2.5
0.2
0.2
g/l
—
8
80
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_CHONDROSARCOMA – Chondrosarcoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).