Benign neoplasm of other and unspecified female genital organs

CD2_BENIGN_FEMALE_GEN_OTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D28
  • Cause of death: ICD-10 D28

2 out of 7 registries used, show all original rules.

986

4. Check minimum number of events

None

986

5. Include endpoints

1601

6. Filter based on genotype QC (FinnGen only)

1601

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Neoplasmata benigna organorum genitalium femininorum aliorum et non specificatorum

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11216 11216 -
Only index persons 10243 10243 -
Unadjusted period prevalence (%)
Whole population 0.32 0.32 -
Only index persons 0.38 0.38 -
Median age at first event (years)
Whole population - 41.94 -
Only index persons - 40.87 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1601 1601 -
Unadjusted period prevalence (%) 0.55 0.55 -
Median age at first event (years) 41.01 41.01 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1436
Matched controls
14359
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D28.0
ICD-10 Finland
Benign neoplasm: Vulva
+∞
323.0
459
*
D28.1
ICD-10 Finland
Benign neoplasm: Vagina
3157.8
290.6
271
*
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
37.9
153.5
197
60
22120
ICD-8 Finland
Benign neoplasm of other female genital organs, Vulva
+∞
129.1
122
*
22101
ICD-8 Finland
Benign neoplasm of other female genital organs, Fallopian tube and broad ligament
+∞
107.7
102
*
22110
ICD-8 Finland
Benign neoplasm of other female genital organs, Vagina
+∞
97.0
92
*
D28.2
ICD-10 Finland
Benign neoplasm: Uterine tubes and ligaments
+∞
76.8
73
*
LEB10
NOMESCO Finland
Excision of lesion of vagina
36.2
75.9
98
29
2210A
ICD-9 Finland
Benign neoplasm of other female genital organs, Fallopian tube and uterine ligaments
+∞
57.7
55
*
D28.9
ICD-10 Finland
Benign neoplasm: Female genital organ, unspecified
569.4
56.0
55
*
22121
ICD-8 Finland
NA
+∞
51.4
49
*
22122
ICD-8 Finland
NA
+∞
50.3
48
*
D28.7
ICD-10 Finland
Benign neoplasm: Other specified female genital organs
+∞
37.7
36
*
22199
ICD-8 Finland
Benign neoplasm of other female genital organs, Unspecified site
+∞
29.3
28
*
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.7
28.6
217
890
2211A
ICD-9 Finland
Benign neoplasm of other female genital organs, Vagina
+∞
28.2
27
*
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
10.5
25.1
49
48
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
4.2
24.2
95
238
22111
ICD-8 Finland
NA
+∞
16.7
16
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.9
12.7
196
1097
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
12.6
518
3843
N75.0
ICD-10 Finland
Cyst of Bartholin gland
6.2
12.6
33
54
8412
FHL
Vaginal tumor removal
37.9
12.2
15
*
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.9
12.1
201
1155
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.5
11.7
938
8008
LEB00
NOMESCO Finland
Biopsy of vagina
3.7
11.6
49
134
LEB20
NOMESCO Finland
Marsupialisation of vaginal cyst
21.6
10.7
15
7
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
10.7
495
3742
N90.7
ICD-10 Finland
Vulvar cyst
10.1
10.5
20
20
2218X
ICD-9 Finland
Benign neoplasm of other female genital organs, Other specified sites of female genital organs
+∞
9.4
9
*
UKC02
NOMESCO Finland
Cystoscopy
1.8
9.0
156
906
8206
FHL
Removal of the parovarial cyst
50.3
8.7
10
*
8473
FHL
Guinea pig or gland excision
9.0
8.5
17
19
J01DA01
ATC
[U] cefalexin; systemic
1.4
8.4
870
7535
R01AD09
ATC
mometasone; nasal
1.4
8.2
636
5229
J02AC01
ATC
fluconazole; systemic
1.4
8.1
688
5749
62212
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Bartholinitis acuta
9.0
8.0
16
18
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
4.8
7.9
25
53
M25.5
ICD-10 Finland
Pain in joint
1.4
7.9
406
3096
D82
ICPC
Teeth/gum disease
1.4
7.6
456
3576
X01
ICPC
Genital pain female
5.8
7.5
20
35
M54.5
ICD-10 Finland
Low back pain
1.4
7.5
448
3503
ULA02
NOMESCO Finland
Kolposcopy
1.7
7.4
161
1006
N39.3
ICD-10 Finland
Stress incontinence
1.7
7.1
149
917
121
Kela drug reimbursment
Severe hypofunction of sexual glands
2.9
7.1
41
144
J01DB01
ATC
cefalexin; oral
1.4
7.1
1122
10283
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
7.0
312
2305
J01AA02
ATC
doxycycline; systemic
1.4
7.0
1106
10117
M01AE02
ATC
naproxen; oral, rectal
1.3
6.9
780
6747
N36.1
ICD-10 Finland
Urethral diverticulum
13.8
6.9
11
8
N02AX02
ATC
tramadol; systemic, rectal
1.4
6.9
536
4374
2200A
ICD-9 Finland
Benign neoplasm of ovary[NEOPLASMA BENIGNUM OVARII]
3.4
6.7
30
89
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.6
412
3235
8204
FHL
Salpingo-oophorectomy
3.0
6.6
36
124
N02BE01
ATC
paracetamol; systemic, rectal
1.5
6.6
1228
11492
21899
ICD-8 Finland
Uterine fibroma
1.9
6.6
92
501
LCD00
NOMESCO Finland
Hysterectomy
1.8
6.4
98
549
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
6.4
282
2079
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
6.4
693
5929
A02BC02
ATC
pantoprazole; systemic
1.3
6.3
897
7981
S18
ICPC
Laceration/cut
1.3
6.3
534
4399
R03AC02
ATC
salbutamol; inhalant
1.3
6.3
727
6274
N89.9
ICD-10 Finland
Noninflammatory disorder of vagina, unspecified
7.1
6.2
14
20
E000001
ATC
NA
1.5
6.2
261
1906
LAC31
NOMESCO Finland
Laparoscopic excision of paraovarian cyst
12.6
6.1
10
8
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
5.2
6.0
17
33
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.0
523
4320

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
251
1472
1.84
15.91
4.6
4.1
—
—
—
0
0
532
4022
1.48
11.70
3.8
3.7
—
—
—
0
0
754
6154
1.43
10.79
2.3
2.1
—
—
—
0
0
1177
10645
1.40
7.87
4.5
4.2
12.0
12.7
mm/h
1.42
1078
9832
607
4990
1.35
7.42
3.5
3.5
25.9
148.8
ng/l
0.69
367
3264
534
4339
1.35
6.94
2.4
2.4
58.3
58.9
u/l
0.05
489
3972
88
485
1.86
6.77
3.3
3.4
—
—
—
0
0
78
418
1.91
6.55
3.9
3.5
25.4
25.0
mmol/l
0.59
70
386
18
46
3.95
6.44
1.1
2.3
1.7
2.5
ug/l
0.66
13
24
83
468
1.82
5.97
2.1
2.0
10878.0
4664.6
u/l
0.43
37
201
109
667
1.68
5.90
3.6
3.3
7.4
7.4
ph
—
8
85
110
675
1.68
5.90
3.6
3.4
5.2
5.2
kpa
0.02
104
623
1066
11578
0.76
5.87
17.0
16.4
13.7
13.7
%
0.07
1042
11306
748
6488
1.29
5.75
5.4
5.1
1.2
1.2
mmol/l
0.60
644
5855
1488
14259
1.62
5.73
15.6
15.0
139.8
139.7
mmol/l
0.68
1453
13877
1491
14298
1.62
5.68
15.7
15.2
3.9
3.9
mmol/l
0.24
1453
13889
1183
10908
1.32
5.60
7.2
7.2
76.1
77.6
u/l
0.63
1103
10218
1070
11587
0.77
5.52
18.4
17.6
330.3
330.6
g/l
0.38
1060
11497
825
7295
1.27
5.25
5.0
5.7
9.9
10.3
umol/l
0.53
775
6884
757
6637
1.27
5.12
3.8
3.9
—
—
—
0
0
247
1858
1.39
5.08
1.2
1.2
—
—
—
0
0
45
220
2.08
4.95
1.4
1.4
28.6
31.0
u/l
0.17
35
186
1043
9534
1.27
4.83
5.5
4.9
4779.1
2747.9
e6/l
0.21
15
132
411
3370
1.30
4.69
2.2
2.1
—
—
—
0
0
72
420
1.75
4.69
2.8
2.9
0.3
0.3
g/l
0.01
26
134
322
2561
1.32
4.59
1.8
1.7
1223.8
1208.0
nmol/l
0.09
236
1880
1059
9784
1.24
4.06
5.2
4.6
—
—
—
0
0
16
55
2.93
3.74
2.9
3.1
—
—
—
0
0
1440
13869
1.38
3.69
14.2
13.4
19.0
21.0
mg/l
1.62
1164
10873
137
985
1.43
3.67
3.2
2.8
3.8
4.0
e9/l
0.51
109
766
34
169
2.03
3.66
1.6
1.5
2.3
4.7
ug/l
0.90
26
146
337
2779
1.27
3.59
1.3
1.3
20.7
34.9
iu/ml
3.56
96
926
515
4466
1.23
3.48
2.2
2.2
—
—
—
0
0
177
1345
1.36
3.43
2.0
2.0
379.5
372.2
nmol/l
0.19
152
1227
534
4656
1.22
3.41
6.5
5.5
—
—
—
0
0
655
5834
1.21
3.35
2.0
2.0
102.6
97.7
pmol/l
1.33
310
2730
857
7834
1.20
3.30
4.1
4.1
6.6
6.6
mmol/l
0.08
796
7269
46
263
1.77
3.29
1.3
1.4
68.0
60.1
mmol/l
0.60
34
206
582
5134
1.21
3.27
7.5
8.2
1.2
1.2
inr
0.08
144
1501
206
1617
1.31
3.21
1.3
1.3
—
—
—
0
0
787
7170
1.19
3.05
6.5
5.9
1.2
1.2
mmol/l
0.24
642
6039
99
697
1.45
3.01
1.7
2.0
—
—
—
0
0
1328
12719
1.26
3.01
6.0
5.6
39.5
39.4
mmol/mol
0.18
1216
11719
203
1607
1.30
2.98
17.9
22.5
1.3
1.3
inr
0.01
27
218
246
2012
1.26
2.79
1.4
1.3
520.0
613.5
titre
0.25
47
455
25
124
2.03
2.76
2.5
3.5
—
—
—
0
0
1355
13044
1.25
2.70
4.3
3.9
1.2
1.3
mmol/l
0.17
1227
11866
175
1381
1.30
2.64
1.5
1.4
—
—
—
0
0
1505
14703
1.39
2.58
11.0
10.5
23.6
23.4
u/l
0.10
1449
14159
20
94
2.14
2.55
1.1
1.1
14.3
13.1
iu/ml
—
5
24
5
7
7.16
2.55
1.0
1.1
—
—
—
0
0
27
143
1.90
2.51
1.9
2.7
—
—
—
0
0
1230
11763
1.20
2.40
5.0
4.6
14.7
14.8
pmol/l
0.39
1107
10739
9
27
3.35
2.39
2.9
1.3
100.5
74.8
ng/l
—
9
27
428
3764
1.19
2.37
2.6
2.9
926.9
1135.9
ng/l
0.63
352
3163
28
155
1.82
2.30
1.9
1.7
—
—
—
0
0
1409
13674
1.25
2.28
4.8
4.4
4.8
4.9
mmol/l
2.38
1294
12622
87
633
1.40
2.27
1.2
1.2
—
—
—
0
0
216
1784
1.24
2.27
2.2
2.1
107.8
116.6
ug/g
0.23
167
1383
184
1493
1.26
2.25
1.7
1.7
—
—
—
0
0
1399
13570
1.25
2.25
4.8
4.4
1.6
1.6
mmol/l
0.35
1277
12453
1383
13399
1.24
2.24
6.0
5.5
3.5
2.1
mu/l
0.38
1276
12310
470
4188
1.17
2.21
2.1
2.1
134.1
176.0
u/l
1.11
435
3919
552
4983
1.16
2.20
3.4
3.3
—
—
—
0
0
312
2690
1.20
2.15
1.3
1.3
6.9
12.4
u/ml
0.98
120
1048
381
3344
1.18
2.14
2.3
2.4
5177.2
5168.3
umol/l
0.00
322
2865
126
986
1.30
2.07
1.3
1.4
—
—
—
0
0
33
199
1.67
2.06
1.1
1.1
1.3
1.3
u/ml
0.03
11
82
39
246
1.60
2.05
1.3
1.7
—
—
—
0
0
34
208
1.65
2.02
1.1
1.1
8.3
2.8
u/ml
1.06
16
101
751
6972
1.15
1.98
6.4
5.6
0.0
0.0
e9/l
0.16
660
5995
62
437
1.44
1.97
2.1
1.9
4.0
2.3
ug/l
0.37
49
387
777
7234
1.14
1.95
6.4
5.8
0.2
0.2
e9/l
0.19
681
6294
418
3724
1.17
1.94
4.4
4.4
0.0
0.0
estimate
0.28
149
1287
37
234
1.59
1.94
1.8
1.4
0.4
0.3
nmol/l
0.44
29
177
245
2089
1.20
1.90
1.2
1.2
—
—
—
0
0
25
143
1.76
1.89
2.4
2.5
—
—
—
0
0
141
1136
1.26
1.87
3.8
3.6
—
—
—
0
0
745
6939
1.14
1.82
6.2
5.6
0.5
0.6
e9/l
0.18
648
5973
23
130
1.78
1.82
1.4
1.4
—
—
—
0
0
48
328
1.48
1.80
2.1
2.3
—
—
—
0
0
7
23
3.05
1.80
1.0
1.1
—
—
—
0
0
927
9769
0.88
1.79
3.7
3.6
—
—
—
0
0
8
29
2.77
1.79
1.4
1.5
—
—
—
0
0
113
891
1.29
1.78
1.5
1.3
—
—
—
0
0
149
1219
1.25
1.74
2.1
3.6
26.3
61.3
u/ml
3.33
144
1180
432
3893
1.15
1.71
3.2
3.1
604.8
383.3
mg/l
0.31
228
2203
14
68
2.07
1.70
2.9
1.8
947.2
752.3
e6/l
—
9
27
223
1908
1.20
1.68
1.6
1.6
—
—
—
0
0
680
6320
1.13
1.68
6.5
5.8
0.7
0.7
%
0.04
627
5843
23
134
1.73
1.66
1.3
1.2
—
—
—
0
0
6
19
3.17
1.66
5.2
8.2
—
—
—
0
0
721
6732
1.13
1.64
6.6
5.8
29.0
28.8
%
0.24
667
6216
1427
13948
1.21
1.63
5.2
5.0
2.8
2.8
mmol/l
1.72
1306
12808
452
4099
1.14
1.62
3.3
3.0
6.6
6.4
mmol/l
0.29
374
3435
155
1286
1.23
1.61
1.9
2.1
0.2
0.2
g/l
0.34
142
1218
16
84
1.91
1.60
1.3
1.2
—
—
—
0
0
13
63
2.07
1.60
1.2
1.2
—
—
—
0
0
697
6511
1.12
1.55
6.4
5.7
2.9
2.8
%
0.99
646
6019
700
6541
1.12
1.55
6.7
6.0
8.3
8.3
%
0.13
649
6076
353
3158
1.15
1.54
1.6
1.8
0.9
1.1
mg/l
0.64
264
2409
1390
13567
1.19
1.54
5.0
4.6
5.8
5.8
mmol/l
0.06
1266
12338
8
33
2.43
1.54
1.4
1.5
—
—
—
0
0
5
15
3.34
1.52
5.8
6.1
—
—
—
0
0
56
756
0.73
1.52
1.4
1.4
—
—
—
0
0
56
409
1.38
1.51
2.8
3.2
—
—
—
0
0
189
1610
1.20
1.51
1.5
1.4
—
—
—
0
0
1546
15268
1.37
1.49
21.4
20.1
91.0
91.1
fl
0.24
1523
15045
1546
15271
1.36
1.45
21.5
20.2
4.4
4.4
e12/l
0.29
1505
14837
1546
15271
1.36
1.45
21.4
20.1
30.1
30.2
pg
0.36
1523
15047
708
6644
1.12
1.43
6.4
5.6
56.6
56.8
%
0.14
656
6166
1545
15263
1.35
1.42
21.5
20.2
263.7
263.0
e9/l
0.18
1507
14877
758
7143
1.12
1.41
6.3
5.6
1.9
1.9
e9/l
0.52
669
6267
77
598
1.30
1.41
1.2
1.3
0.2
1.1
u/ml
—
5
52
671
6282
1.12
1.40
3.0
2.8
87.2
95.5
ug/l
0.95
604
5803
1546
15276
1.35
1.40
21.6
20.3
131.8
131.7
g/l
0.10
1526
15057
29
433
0.66
1.39
1.9
2.1
38.2
37.9
g/l
0.06
22
373
36
247
1.47
1.38
1.2
1.8
—
—
—
0
0
28
182
1.55
1.37
1.7
1.4
277.1
297.9
pmol/l
0.14
23
137
0
37
0.00
1.34
0.0
2.4
—
—
—
0
0
14
75
1.87
1.34
2.4
3.8
—
—
—
0
0
1545
15272
1.33
1.32
21.6
20.2
6.7
6.6
e9/l
0.25
1502
14833
753
7112
1.11
1.32
4.1
4.0
0.0
0.0
estimate
1.08
150
1284
1464
14388
1.20
1.30
14.0
12.6
—
—
—
0
0
446
4096
1.12
1.29
3.9
3.8
11.0
7.5
mg/mmol
0.61
244
2340
334
3014
1.14
1.29
1.6
1.7
30741185.5
25454994.8
pmol/l
0.06
270
2475
6
25
2.41
1.24
1.0
1.0
—
—
—
0
0
737
6972
1.11
1.23
4.0
4.0
0.0
0.0
estimate
0.00
147
1278
64
496
1.30
1.22
4.3
4.0
—
—
—
0
0
136
1151
1.20
1.20
3.3
3.9
0.0
0.1
%
1.81
32
271
34
239
1.43
1.18
1.2
1.1
4.0
0.9
u/ml
0.71
14
94
312
2820
1.13
1.18
1.4
1.4
2.2
2.2
g/l
0.31
172
1649
368
3369
1.12
1.12
1.3
1.3
0.5
1.6
u/ml
4.75
96
882
29
200
1.46
1.12
1.2
1.2
—
—
—
0
0
172
1499
1.17
1.10
3.4
3.8
6.4
13.2
ug/l
1.24
132
1195
110
924
1.20
1.08
1.3
1.2
460.7
138.2
u/ml
0.45
102
847
30
211
1.43
1.06
1.3
1.2
—
—
—
0
0
29
203
1.44
1.05
1.6
1.2
—
—
nmol/l
—
0
0
7
33
2.13
1.05
1.0
1.0
—
—
—
0
0
7
33
2.13
1.05
1.0
1.0
—
—
—
0
0
7
33
2.13
1.05
1.0
1.0
—
—
—
0
0
741
7051
1.09
1.05
5.4
5.4
0.0
0.0
estimate
0.50
144
1285
8
148
0.54
1.03
1.3
1.6
—
—
—
0
0
136
1170
1.18
1.03
1.6
1.6
—
—
—
0
0
25
171
1.47
1.02
1.8
1.8
91.9
89.8
%
1.40
25
171
142
1227
1.17
1.02
3.2
3.2
95.6
78.2
ng/l
1.11
118
1033
139
1200
1.17
1.01
3.3
3.8
0.4
1.0
%
2.87
35
295
42
317
1.33
1.00
1.7
1.7
8025.6
12281.2
e6/l
0.43
28
228
128
1099
1.18
1.00
3.1
3.7
0.5
0.6
%
0.47
31
203
7
35
2.00
1.00
1.1
1.3
—
—
—
0
0
7
35
2.00
1.00
1.9
2.3
—
—
—
0
0
7
35
2.00
1.00
1.0
1.4
—
—
—
0
0
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
5
23
2.18
0.98
1.0
1.2
1.4
1.6
umol/24h
—
5
23
37
275
1.35
0.97
2.1
2.1
129.5
128.7
g/l
0.07
25
193
408
4387
0.91
0.97
3.6
3.6
7.4
7.4
ph
0.48
89
820
151
1326
1.15
0.90
1.4
1.4
—
—
—
0
0
34
253
1.35
0.90
2.6
2.3
16.6
16.2
%
0.32
15
115
6
29
2.07
0.89
1.5
3.5
—
—
—
0
0
98
832
1.19
0.89
1.2
1.2
—
—
—
0
0
115
994
1.17
0.85
2.7
2.9
10.0
10.1
g/l
0.11
106
899
400
3732
1.10
0.85
3.5
3.6
—
—
—
0
0
114
985
1.17
0.85
3.0
3.2
—
—
—
0
0
39
502
0.77
0.85
1.0
1.1
—
—
—
0
0
121
1051
1.16
0.85
1.3
1.2
—
—
—
0
0
10
57
1.76
0.83
2.2
2.8
632.7
1131.2
u/ml
—
10
57
22
154
1.43
0.83
2.0
1.7
279.7
1728.4
u/ml
0.40
22
148
27
197
1.38
0.82
1.4
1.7
0.6
0.7
g/l
0.13
17
151
124
1084
1.16
0.81
3.5
3.9
0.0
0.8
%
0.80
31
223
167
1491
1.13
0.80
2.0
2.4
5.8
6.6
umol/l
0.26
148
1269
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
6
33
1.82
0.79
1.2
1.2
69.5
75.7
mu/l
—
6
27
184
2038
0.89
0.78
2.7
2.7
5.4
4.2
e6/l
0.55
104
1012
31
234
1.33
0.78
1.5
1.2
0.6
0.7
nmol/l
0.21
31
224
29
218
1.34
0.75
1.5
1.2
—
—
—
0
0
26
192
1.36
0.75
1.4
1.2
—
—
—
0
0
11
67
1.65
0.75
2.4
4.1
—
—
—
0
0
27
201
1.35
0.74
1.0
1.0
—
—
—
0
0
17
116
1.47
0.74
1.8
2.7
7.9
26.5
mg/l
—
8
78
1229
12521
0.92
0.71
14.5
14.6
38.9
38.7
%
0.30
845
8893
14
206
0.68
0.71
1.5
1.4
—
—
—
0
0
135
1201
1.14
0.71
1.1
1.2
—
—
—
0
0
7
41
1.71
0.70
1.1
1.0
—
—
—
0
0
224
2056
1.10
0.69
2.5
2.3
12.7
12.9
umol/l
0.19
204
1888
12
77
1.56
0.68
1.2
1.8
6.4
9.1
ug/l
0.66
12
65
112
988
1.14
0.67
3.2
2.6
76.6
72.9
e9/l
0.48
93
734
28
214
1.31
0.67
1.5
1.3
—
—
—
0
0
846
8197
1.07
0.66
8.2
8.8
4.1
4.0
e9/l
0.48
747
7146
19
259
0.73
0.65
1.2
1.9
1.0
0.8
nmol/l
0.35
13
204
20
146
1.37
0.64
1.1
1.1
4.6
3.8
u/ml
—
5
55
6
105
0.57
0.61
1.7
1.6
1.2
1.0
g/l
—
6
105
42
343
1.23
0.61
3.6
3.2
7.4
7.4
ph
0.03
33
280
25
191
1.31
0.61
2.5
2.6
—
—
—
0
0
20
267
0.75
0.61
2.9
2.4
3.7
84.2
ug/min
—
7
171
149
1350
1.11
0.60
2.9
2.6
1.9
1.9
%
0.12
120
1184
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
62
530
1.18
0.58
1.7
1.8
1.6
1.6
g/l
0.10
52
459
14
196
0.71
0.57
1.1
1.3
99.0
117.2
u/ml
—
6
38
45
375
1.21
0.56
2.0
2.2
—
—
—
0
0
116
1043
1.12
0.55
2.4
2.3
4.8
5.5
ug/l
0.33
91
897
89
787
1.14
0.54
5.1
4.3
—
—
—
0
0
16
116
1.38
0.54
1.2
1.2
—
—
—
0
0
6
38
1.58
0.54
1.2
1.6
—
—
—
0
0
6
38
1.58
0.54
1.3
1.2
572.2
265.9
pmol/l
—
6
30
21
160
1.32
0.53
1.1
1.0
6.1
3.1
u/ml
—
6
57
30
241
1.25
0.52
1.5
1.6
—
—
—
0
0
16
117
1.37
0.52
1.6
2.3
2.1
2.3
u/field
—
10
50
321
3035
1.07
0.52
4.7
4.5
1.0
1.0
kg/l
0.12
50
449
9
133
0.67
0.52
1.2
1.3
34.7
32.9
g/l
—
9
118
207
2224
0.92
0.52
2.7
2.5
1.3
1.5
e6/l
0.34
128
1192
343
3251
1.07
0.52
1.5
1.5
23.0
22.1
nmol/l
0.50
264
2735
541
5203
1.06
0.51
2.9
3.3
2.4
2.4
mmol/l
0.33
441
4541
26
206
1.27
0.51
1.9
1.3
—
—
—
0
0
15
109
1.38
0.51
4.7
6.3
—
—
—
0
0
15
109
1.38
0.51
2.7
1.8
0.9
1.2
e9/l
—
5
72
450
4697
0.94
0.50
2.9
2.8
—
—
—
0
0
6
41
1.47
0.50
1.0
1.1
—
—
—
0
0
231
2161
1.08
0.50
2.9
3.0
0.8
0.8
mmol/l
0.23
205
1997
38
453
0.83
0.48
11.4
8.5
—
—
—
0
0
88
787
1.13
0.47
1.7
1.8
1.1
1.4
g/l
2.37
81
711
34
282
1.21
0.46
4.0
3.4
2.4
2.9
mmol/l
0.30
23
206
169
1567
1.09
0.46
1.7
1.8
—
—
—
0
0
29
237
1.23
0.45
2.8
2.6
8.7
8.1
kpa
0.98
29
216
7
50
1.40
0.45
1.1
1.1
114.6
192.4
iu/ml
—
7
50
35
416
0.84
0.44
1.4
1.3
162.0
229.9
miu/ml
0.80
21
202
53
608
0.87
0.44
7.9
8.5
—
—
—
0
0
79
707
1.12
0.43
1.1
1.1
—
254.7
—
0
17
6
93
0.64
0.42
1.0
1.2
5.5
6.6
mmol/l
—
6
86
12
87
1.38
0.42
2.3
1.8
45.0
48.2
%
—
5
11
8
57
1.41
0.42
1.1
13.0
—
—
—
0
0
242
2559
0.94
0.42
3.6
3.5
381.4
247.3
ng/l
0.37
172
1900
184
1722
1.08
0.41
2.3
2.4
21.5
21.8
%
0.14
148
1464
0
15
0.00
0.41
0.0
1.7
—
—
—
0
0
0
17
0.00
0.40
0.0
1.7
—
1.6
—
0
12
0
17
0.00
0.40
0.0
1.8
—
0.0
—
0
10
601
6189
0.95
0.40
9.2
9.1
0.0
0.0
e9/l
2.41
509
5047
29
347
0.83
0.40
4.4
4.4
—
—
—
0
0
11
149
0.74
0.40
2.1
2.1
32.9
31.9
pg
0.49
11
149
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
4.4
—
34.4
—
0
13
7
101
0.69
0.39
1.9
1.4
—
—
—
0
0
23
281
0.82
0.39
1.7
1.5
—
—
—
0
0
10
71
1.41
0.39
1.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
2.8
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
6.2
—
0
19
231
2187
1.07
0.38
1.7
1.7
—
—
—
0
0
27
323
0.83
0.38
1.1
1.3
3.7
3.8
mmol/l
0.35
27
304
193
1817
1.07
0.38
1.9
1.9
—
—
—
0
0
271
2581
1.06
0.37
2.5
2.6
465.4
508.9
mosm/kgh2o
3.01
222
2188
11
147
0.75
0.37
1.5
1.3
—
—
—
0
0
42
365
1.15
0.36
2.0
2.1
15.8
11.9
mg/l
0.32
36
336
130
1208
1.08
0.36
1.3
1.3
—
—
—
0
0
23
189
1.22
0.36
1.2
1.1
—
—
—
0
0
266
2788
0.94
0.36
2.8
2.8
2.5
2.5
mmol/l
0.27
232
2460
21
171
1.23
0.35
3.8
4.5
392.0
80.6
u/ml
—
8
49
5
77
0.65
0.35
1.0
1.5
—
—
—
0
0
33
384
0.86
0.35
3.8
3.4
2.4
1.9
ratio
—
5
30
363
3494
1.05
0.34
2.4
2.2
3.0
3.0
mg/l
0.04
306
2969
127
1182
1.08
0.34
3.7
4.3
—
—
—
0
0
12
156
0.77
0.34
1.6
2.0
—
—
—
0
0
197
1864
1.06
0.34
2.4
2.3
2.4
2.4
g/l
0.08
178
1716
292
2796
1.05
0.34
2.5
2.5
5.9
7.9
e6/l
2.09
252
2437
19
232
0.82
0.33
1.2
1.3
—
—
—
0
0
13
100
1.30
0.33
1.8
1.9
—
1.2
—
0
5
15
118
1.27
0.33
1.5
1.4
4443.5
132189.8
e6/l
—
8
82
12
155
0.77
0.33
2.2
2.8
—
—
—
0
0
29
247
1.18
0.33
4.2
2.1
—
—
—
0
0
24
285
0.84
0.32
2.4
2.5
1.4
1.5
mmol/l
0.32
24
275
23
274
0.84
0.32
1.6
1.4
—
—
—
0
0
623
6081
1.04
0.32
4.4
4.3
35.7
35.6
g/l
0.22
572
5635
114
1062
1.08
0.31
1.4
1.3
—
—
—
0
0
97
1047
0.92
0.31
5.8
3.2
4.6
4.5
pmol/l
0.47
84
915
23
272
0.84
0.30
1.6
1.4
—
—
—
0
0
123
1313
0.93
0.30
2.0
2.2
30.9
37.8
u/l
1.31
105
1112
7
55
1.27
0.30
3.0
2.2
—
—
—
0
0
20
166
1.21
0.30
1.8
1.6
45.5
59.6
%
—
10
98
20
166
1.21
0.30
1.3
1.5
—
23.0
—
0
10
44
493
0.89
0.29
1.7
1.8
22.7
21.0
s
0.30
38
430
359
3711
0.96
0.29
6.1
6.4
—
—
—
0
0
160
1517
1.06
0.28
5.0
5.8
104.6
104.2
mmol/l
0.41
155
1482
9
116
0.77
0.27
1.1
1.1
—
—
—
0
0
349
3604
0.96
0.27
3.1
2.9
—
—
—
0
0
9
120
0.75
0.27
1.0
1.1
—
—
—
0
0
69
750
0.92
0.27
2.9
3.4
—
—
—
0
0
56
509
1.10
0.27
1.1
1.1
—
—
—
0
0
37
328
1.13
0.27
1.2
1.2
—
—
—
0
0
128
1207
1.07
0.26
1.6
1.5
—
—
—
0
0
8
66
1.21
0.26
2.9
2.1
—
—
—
0
0
14
113
1.24
0.26
1.5
1.1
429.4
397.0
nmol/l
0.20
14
103
13
104
1.25
0.26
1.2
1.2
—
—
—
0
0
32
362
0.88
0.25
1.1
1.1
—
—
—
0
0
175
1669
1.05
0.25
5.1
4.5
1.1
1.0
mmol/l
0.56
158
1526
16
132
1.21
0.25
1.1
1.1
—
75.9
—
0
7
15
123
1.22
0.25
1.5
1.7
6.8
6.5
g/l
—
8
88
15
123
1.22
0.25
1.5
1.7
0.3
0.3
g/l
—
8
89
15
123
1.22
0.25
1.5
1.7
2.7
2.9
g/l
—
8
87
9
74
1.22
0.25
1.0
1.1
—
—
—
0
0
77
829
0.93
0.25
1.7
1.8
—
—
—
0
0
14
114
1.23
0.25
1.1
1.1
—
—
—
0
0
53
484
1.10
0.24
5.5
4.6
1.6
1.5
%
0.24
53
456
10
126
0.79
0.24
2.3
2.5
—
—
—
0
0
18
152
1.19
0.23
1.2
1.1
—
—
—
0
0
11
136
0.81
0.23
1.5
1.1
—
—
—
0
0
5
39
1.28
0.23
1.2
1.1
—
—
—
0
0
49
448
1.10
0.22
1.3
1.4
329.0
302.7
ug/g
0.36
28
254
7
91
0.77
0.22
1.3
1.6
10.1
10.8
%
—
7
91
15
125
1.20
0.22
1.5
1.6
—
—
—
0
0
18
153
1.18
0.22
1.3
1.5
—
—
—
0
0
23
263
0.87
0.22
1.3
1.3
—
—
—
0
0
34
305
1.12
0.22
2.9
4.0
31.5
24.0
mg/l
0.28
17
183
0
11
0.00
0.21
0.0
1.2
—
140.6
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.0
—
0
5
57
616
0.92
0.21
5.8
7.7
25.4
24.4
mmol/l
1.06
49
573
8
102
0.78
0.21
1.5
1.3
—
—
—
0
0
8
103
0.78
0.21
1.1
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
143
1369
1.05
0.20
5.7
6.1
2.1
1.3
mmol/l
1.64
113
1079
6
50
1.20
0.19
1.7
1.2
—
—
—
0
0
22
193
1.14
0.19
1.0
1.1
—
—
—
0
0
116
1217
0.95
0.19
2.9
3.5
1.2
1.2
mmol/l
0.30
102
1051
6
51
1.18
0.19
1.2
1.1
—
—
—
0
0
60
559
1.08
0.19
1.3
1.3
—
—
—
0
0
26
291
0.89
0.19
2.9
2.3
—
—
—
0
0
25
222
1.13
0.19
1.4
1.5
—
—
—
0
0
32
289
1.11
0.19
3.1
3.4
0.9
0.8
nmol/l
0.41
26
225
40
436
0.92
0.18
2.5
1.9
6.7
4.6
iu/l
0.43
13
147
358
3662
0.97
0.18
3.0
3.0
0.3
0.4
e6/l
2.09
267
2715
115
1099
1.05
0.17
4.3
3.0
5.9
5.8
kpa
0.13
110
1069
36
329
1.10
0.17
1.3
1.4
—
29.7
—
0
6
11
91
1.21
0.17
1.3
1.6
8.4
6.8
mmol/l
—
6
61
52
558
0.93
0.17
4.6
3.2
24.6
24.3
mmol/l
0.20
46
496
7
62
1.13
0.17
1.1
1.3
143.9
133.6
nmol/l
—
7
62
25
278
0.90
0.17
2.4
1.7
—
—
—
0
0
120
1150
1.05
0.17
1.2
1.2
179.3
153.3
iu/ml
0.32
44
451
5
69
0.72
0.17
1.0
1.2
97.0
387.7
u/l
—
5
62
8
68
1.18
0.16
3.9
1.8
—
—
—
0
0
8
69
1.16
0.16
1.0
1.1
—
—
—
0
0
24
266
0.90
0.15
2.4
2.6
7.8
7.4
mmol/l
0.19
24
258
8
73
1.10
0.15
2.0
1.8
25.4
7.1
nmol/l
—
8
57
11
129
0.85
0.14
1.1
1.1
—
—
—
0
0
100
959
1.05
0.14
5.7
6.8
—
—
—
0
0
366
3726
0.98
0.13
1.5
1.5
—
—
—
0
0
91
949
0.96
0.13
2.7
2.3
—
—
—
0
0
142
1376
1.04
0.13
5.7
6.1
5.2
5.1
kpa
0.53
135
1321
142
1376
1.04
0.13
5.8
6.1
12.5
12.7
kpa
0.10
134
1317
343
3371
1.02
0.12
4.2
3.9
—
—
—
0
0
102
983
1.04
0.12
7.2
6.5
8.8
8.9
mmol/l
0.04
93
935
12
104
1.16
0.12
1.1
1.1
—
—
—
0
0
112
1083
1.04
0.12
4.4
3.0
2.3
2.1
mmol/l
0.17
94
892
56
589
0.95
0.12
1.8
1.6
—
—
—
0
0
388
3939
0.98
0.12
3.0
3.1
52.0
53.6
e6/l
0.02
303
2947
27
291
0.93
0.11
4.1
3.6
—
—
—
0
0
10
115
0.87
0.10
1.1
1.3
—
—
—
0
0
17
187
0.91
0.10
1.0
1.1
—
—
—
0
0
486
4806
1.02
0.10
3.4
3.6
114.0
102.2
e6/l
0.09
329
3246
12
135
0.89
0.10
2.6
2.2
—
—
—
0
0
32
340
0.94
0.09
3.8
1.5
—
—
—
0
0
6
57
1.05
0.08
1.8
1.6
—
—
—
0
0
6
57
1.05
0.08
1.7
1.2
—
—
—
0
0
191
1876
1.02
0.08
1.7
2.0
28.7
29.3
s
0.94
183
1819
32
338
0.95
0.08
3.8
1.4
—
—
—
0
0
11
123
0.89
0.08
1.6
1.6
47.0
37.0
%
—
6
69
24
256
0.94
0.07
9.8
6.6
105.7
105.1
mmol/l
0.20
24
233
24
256
0.94
0.07
9.7
6.6
10.8
11.0
mmol/l
0.08
24
233
27
254
1.06
0.07
4.2
3.2
—
—
—
0
0
333
3291
1.01
0.07
4.0
3.9
—
—
—
0
0
6
75
0.80
0.07
15.2
12.8
0.7
0.6
mmol/l
—
6
70
32
337
0.95
0.07
3.8
1.4
—
—
—
0
0
8
76
1.05
0.07
1.4
1.2
—
—
—
0
0
27
286
0.94
0.07
2.7
3.6
59.6
57.5
%
0.50
27
286
8
77
1.04
0.07
2.1
2.1
1.7
2.3
ug/l
—
8
67
340
3437
0.99
0.07
3.4
3.5
96.5
94.7
%
0.70
326
3334
9
88
1.02
0.07
1.3
1.8
74.7
73.6
%
—
9
82
108
1057
1.02
0.06
2.8
2.9
275.3
182.2
ng/l
0.52
102
958
9
104
0.86
0.06
1.1
1.4
—
—
—
0
0
34
355
0.96
0.06
1.1
1.3
459.2
503.8
mg/l
0.36
34
338
15
139
1.08
0.05
1.1
1.5
—
—
—
0
0
392
3891
1.01
0.05
1.7
1.6
1.3
1.4
mmol/l
0.38
339
3284
32
333
0.96
0.05
3.5
1.4
—
—
—
0
0
110
1118
0.98
0.04
2.8
2.6
66.2
66.8
g/l
0.33
98
1008
30
310
0.97
0.03
4.0
1.5
—
—
—
0
0
313
3113
1.01
0.02
4.2
4.4
—
—
—
0
0
92
911
1.01
0.01
3.2
2.6
4.4
4.5
kpa
0.40
87
882
71
718
0.99
0.01
1.4
1.3
28.5
32.1
iu/l
0.41
65
617
47
477
0.98
0.01
3.3
3.1
160.5
587.7
u/ml
0.76
40
412
49
483
1.01
0.01
5.8
4.6
0.9
0.9
%
0.18
49
455
16
154
1.04
0.00
2.6
2.8
—
—
—
0
0
35
356
0.98
0.00
1.1
1.2
—
—
—
0
0
21
206
1.02
0.00
1.4
1.2
3.3
4.3
u/ml
0.31
11
78
15
148
1.01
0.00
1.2
1.2
—
—
—
0
0
16
158
1.01
0.00
4.9
1.6
—
—
—
0
0
19
192
0.99
0.00
1.1
1.2
317.2
254.8
u/ml
—
10
118
77
774
0.99
0.00
2.8
2.5
—
—
—
0
0
10
99
1.01
0.00
1.1
1.3
—
2161.5
—
0
16
14
141
0.99
0.00
2.7
3.1
—
—
—
0
0
20
201
0.99
0.00
1.0
1.1
—
—
—
0
0
22
221
1.00
0.00
7.6
2.0
—
—
—
0
0
26
259
1.00
0.00
3.9
1.5
—
—
—
0
0
47
471
1.00
0.00
1.2
1.2
—
—
—
0
0
10
97
1.03
0.00
1.6
2.3
—
—
—
0
0
14
143
0.98
0.00
1.8
1.3
—
—
—
0
0
14
143
0.98
0.00
1.8
1.3
—
—
—
0
0
14
143
0.98
0.00
1.8
1.3
—
—
—
0
0
14
143
0.98
0.00
1.8
1.3
—
—
—
0
0
22
223
0.99
0.00
1.1
1.3
—
—
—
0
0
57
567
1.01
0.00
2.9
2.2
1.2
1.1
%
0.28
57
562
28
285
0.98
0.00
1.1
1.5
—
—
—
0
0
12
115
1.04
0.00
1.8
1.2
1.5
0.8
u/ml
—
5
42
22
225
0.98
0.00
1.1
1.1
—
—
—
0
0
8
79
1.01
0.00
2.1
2.1
2.3
3.1
ug/l
—
8
71
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.0
1.1
1762.0
1766.6
miu/ml
—
5
58
0
5
0.00
0.00
0.0
2.0
—
4.5
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
6.1
—
0
7
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
0.00
2.9
3.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.90
0.00
1.7
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1263.8
—
0
5
5
51
0.98
0.00
1.6
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
13
130
1.00
0.00
2.2
1.7
—
—
—
0
0
20
200
1.00
0.00
1.0
1.1
—
—
—
0
0
5
57
0.88
0.00
1.8
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
1.2
2.5
2594.2
1847.1
ml
—
6
59
7
72
0.97
0.00
1.1
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
8.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_FEMALE_GEN_OTH and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_FEMALE_GEN_OTH 1.037 [0.92, 1.17] 0.546
Birth year 0.991 [0.98, 1.0] 0.056

During the follow-up period (1.1.1998 — 31.12.2019), 555 out of 5027 females with CD2_BENIGN_FEMALE_GEN_OTH died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_FEMALE_GEN_OTH.

N-year risk Females Males
1 0.103% No data
5 0.612% No data
10 1.446% No data
15 2.636% No data
20 4.381% No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_FEMALE_GEN_OTH – Benign neoplasm of other and unspecified female genital organs

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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