Benign neoplasm: Female genital organ, unspecified

CD2_BENIGN_FEMALE_GEN_NOS

muscle cancer: A musculoskeletal system cancer that is located_in muscle.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule only females	293218
2. Check conditions None	293218
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D28.9& Hospital discharge: ICD-9 — 221[8-9] Hospital discharge: ICD-8 — 2219 Cause of death: ICD-10 — D28.9& Cause of death: ICD-9 — 221[8-9] Cause of death: ICD-8 — 2219 2 out of 7 registries used, show all original rules.	109
4. Check minimum number of events None	109
5. Include endpoints None	109
6. Filter based on genotype QC (FinnGen only)	107

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D28
Name in latin: Neoplasma benignum organi genitalis feminini non specificati

NAME	CD2_BENIGN_FEMALE_GEN_NOS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D289
HD_ICD_9	221[8-9]
HD_ICD_8	2219
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D289
COD_ICD_9	221[8-9]
COD_ICD_8	2219
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Female genital organ, unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	995	995	-
Only index persons	837	837	-
Unadjusted period prevalence (%)
Whole population	0.03	0.03	-
Only index persons	0.03	0.03	-
Median age at first event (years)
Whole population	-	44.49	-
Only index persons	-	42.31	-

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	107	107	-
Unadjusted period prevalence (%)	0.04	0.04	-
Median age at first event (years)	39.11	39.11	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
109: Matched controls
1090

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D28.9

ICD-10 Finland

Benign neoplasm: Female genital organ, unspecified

+∞

77.6

22199

ICD-8 Finland

Benign neoplasm of other female genital organs, Unspecified site

+∞

33.0

LFB10

NOMESCO Finland

Excision of lesion of vulva or perineum

29.2

10.1

2218X

ICD-9 Finland

Benign neoplasm of other female genital organs, Other specified sites of female genital organs

+∞

9.5

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40761536) Microorganisms panel - Urine sediment

2.53

2.98

5.3

3.7

—

(3022806) Fractional oxyhemoglobin in Capillary blood

5.22

2.43

1.5

2.6

90.68

89.52

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

110

2.13

2.25

1.8

1.9

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

182

1.89

2.15

2.1

1.8

435.43

496.15

pmol/l

0.67

150

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.67

2.08

1.2

1.5

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

3.24

2.06

2.1

1.5

—

(3037467) Urinalysis macro (dipstick) panel - Urine

667

1.83

2.02

3.8

4.6

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

3.49

2.00

1.9

1.5

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

3.18

1.83

1.6

1.5

—

(3013290) Carbon dioxide [Partial pressure] in Blood

3.46

1.77

1.5

3.7

4.75

5.00

kpa

—

(3027315) Oxygen [Partial pressure] in Blood

3.46

1.77

1.5

3.7

8.68

9.16

kpa

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.00

1.67

3.2

3.6

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

1.37

0.0

1.6

—

1.16

—

(3029937) Albumin [Presence] in Urine by Test strip

259

1.58

1.37

4.5

4.2

0.00

estimate

-0.00

(3000330) Specific gravity of Urine by Test strip

2.19

1.34

2.7

3.3

—

(3048689) Calprotectin [Mass/mass] in Stool

111

1.74

1.21

2.6

1.8

136.69

118.03

ug/g

0.12

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

377

1.49

1.20

4.9

3.9

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

1.16

0.0

1.6

—

0.23

—

(3022145) Colonoscopy Study observation

114

1.69

1.11

1.4

1.2

—

(3009261) Glucose [Presence] in Urine by Test strip

482

1.43

1.05

4.6

4.0

0.00

estimate

-0.00

(3021960) Folate [Moles/volume] in Serum or Plasma

231

1.48

0.98

1.5

26.94

23.20

nmol/l

0.48

185

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

734

1.47

0.94

7.6

7.0

73.00

76.68

u/l

0.63

669

(40768797) Stomach Pathology biopsy report

128

1.59

0.94

1.2

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

423

1.39

0.89

2.7

2.3

77.18

77.97

nmol/l

0.07

372

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

300

1.41

0.88

2.2

55.39

53.98

u/l

0.10

270

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

195

0.62

0.82

1.5

1.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

285

1.39

0.82

5.0

3.5

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

304

1.38

0.81

2.2

2.6

30.91

28.19

u/l

0.26

291

(3021601) Nitrite [Presence] in Urine by Test strip

477

1.36

0.81

6.1

5.5

0.00

estimate

-0.00

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

150

1.50

0.81

1.5

1.6

—

(3022621) pH of Urine by Test strip

1.77

0.79

5.2

2.9

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.78

0.0

1.1

—

(3013512) EKG study

278

1.38

0.78

5.4

3.6

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

117

1.54

0.77

4.6

4.4

35.00

34.24

0.10

(3014051) Protein [Presence] in Urine by Test strip

2.13

0.75

2.0

2.8

—

(3035350) Ketones [Presence] in Urine by Test strip

481

1.34

0.75

4.6

3.9

0.00

estimate

-0.00

102

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.60

0.73

2.8

4.1

1.24

1.23

mmol/l

0.55

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

1.97

0.71

1.0

1.5

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

594

1.33

0.71

2.9

3.0

43.65

42.06

u/l

0.08

549

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

1.82

0.67

1.0

1.5

337.60

152.97

ug/l

—

(3019832) Treponema pallidum Ab [Presence] in Serum

104

1.51

0.67

1.7

1.6

—

(3021589) Normoblasts [#/volume] in Blood

420

1.30

0.64

11.1

9.2

0.00

e9/l

0.50

345

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

884

1.46

0.63

11.8

12.8

81.36

80.94

ml/min/173m2

0.07

719

(3015377) Calcium [Moles/volume] in Serum or Plasma

345

1.30

0.61

3.0

3.2

2.37

mmol/l

0.04

308

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.61

0.0

1.2

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.61

0.0

1.2

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.61

0.0

1.9

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.60

0.0

1.4

—

(4035726) Immunohistochemistry procedure

1.49

0.60

1.4

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.52

0.59

1.0

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

425

1.28

0.57

3.1

2.7

88.34

77.74

ug/l

0.16

392

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.48

0.57

1.1

1.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.52

0.55

1.1

1.3

—

(3045414) Leukocytes [Presence] in Urine

1.57

0.54

1.8

1.5

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.53

0.52

1.5

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.59

0.50

1.3

2.1

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.56

0.49

1.4

4.1

24.49

25.57

mmol/l

—

(3031040) Bacteria [#/volume] in Urine by Automated count

662

1.26

0.49

4.8

—

341.75

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

452

1.24

0.48

2.0

2.4

—

(3026008) Bacteria identified in Urine by Culture

336

1.25

0.47

2.5

3.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

205

1.28

0.44

1.5

1.4

1.96

2.54

g/l

1.09

114

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

595

1.23

0.44

2.7

3.3

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.43

0.43

1.1

1.5

—

(3019225) pH of Specimen

1.41

0.42

3.9

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

0.41

0.0

1.0

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.41

0.0

1.1

—

112.80

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.5

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.41

0.0

1.3

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.40

0.0

1.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

208

1.26

0.40

2.9

3.9

—

(3013707) Erythrocyte sedimentation rate by Westergren method

721

1.23

0.40

4.6

4.3

11.06

12.24

mm/h

0.53

645

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.39

0.0

1.0

—

4.20

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.39

0.0

1.4

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.39

0.0

1.8

—

(3030467) Casts [#/volume] in Urine by Automated count

247

1.24

0.38

3.1

3.3

0.59

0.40

e6/l

0.26

172

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

230

0.79

0.36

1.6

1.4

—

(3018010) Neutrophils/100 leukocytes in Blood

443

1.19

0.36

4.7

5.5

53.20

57.51

1.28

409

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.38

0.35

1.8

1.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

767

1.22

0.35

4.7

4.3

14.70

14.66

pmol/l

0.04

692

(3037522) Nuclear Ab [Titer] in Serum

143

0.74

0.34

1.4

1.3

—

572.63

titre

—

(36660697) Celiac disease serology panel - Serum

0.68

0.34

1.0

1.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.35

0.34

1.2

1.5

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

194

1.24

0.33

1.4

1.3

37.48

33.98

iu/ml

—

(3006504) Eosinophils/100 leukocytes in Blood

436

1.18

0.32

4.8

5.6

3.33

2.68

0.95

398

(3003396) Base excess in Arterial blood by calculation

0.69

0.32

10.9

4.8

4.83

1.62

mmol/l

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.40

0.32

6.0

1.8

—

(3000494) Fungus identified in Specimen by Culture

111

1.30

0.32

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

102

1.31

0.31

1.6

1.4

—

(3001604) Monocytes [#/volume] in Blood

467

1.17

0.31

5.6

0.58

0.54

e9/l

0.51

404

(3006315) Basophils [#/volume] in Blood

467

1.17

0.31

5.6

0.04

e9/l

0.24

404

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

140

1.25

0.29

2.0

1.8

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

400

1.17

0.29

2.2

1.9

99.72

99.39

pmol/l

0.02

177

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

139

0.77

0.29

2.2

3.0

7.37

4.98

e6/l

—

(3002030) Lymphocytes/100 leukocytes in Blood

450

1.16

0.28

4.9

5.7

30.72

28.31

0.53

415

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

113

1.27

0.28

5.4

6.1

—

(3026493) Urate [Moles/volume] in Serum or Plasma

217

1.20

0.27

2.7

328.13

6416.51

umol/l

1.30

188

(3022217) INR in Platelet poor plasma by Coagulation assay

413

1.15

0.26

11.1

1.00

1.19

inr

4.10

126

(40768804) Tissue Pathology biopsy report

433

1.15

0.25

2.4

2.0

—

(3002256) Pathology report gross observation

124

1.24

0.25

1.4

1.3

—

(4200892) Spirometry reversibility

1.20

0.25

1.3

1.4

—

(3013115) Eosinophils [#/volume] in Blood

483

1.15

0.25

5.8

5.6

0.21

0.18

e9/l

0.74

424

(3019309) Folate [Moles/volume] in Red Blood Cells

182

1.19

0.23

2.6

1.7

1191.00

1188.01

nmol/l

0.00

136

(40761535) Cells panel - Urine sediment

1.29

0.23

2.1

3.1

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

192

1.18

0.23

1.2

1.3

1.34

8.87

u/ml

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.26

0.23

1.6

1.4

—

(36304419) Bacteria [Presence] in Urine

250

1.16

0.22

3.2

3.1

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

1.23

0.22

1.6

2.3

26.54

24.68

mmol/l

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.23

0.22

2.2

1.9

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

544

0.88

0.22

4.7

4.0

6.45

6.48

mmol/l

0.06

497

(3019069) Monocytes/100 leukocytes in Blood

437

1.13

0.22

5.1

5.9

8.16

8.21

0.04

402

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.20

0.22

2.4

1.9

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.21

0.0

1.0

—

100.45

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.3

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.0

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.3

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.21

0.0

1.7

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.21

0.0

3.6

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.21

0.0

1.2

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.3

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.0

—

19.98

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.21

0.0

3.3

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

0.21

0.0

1.7

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.0

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

100

977

1.28

0.21

14.8

15.5

68.15

69.23

umol/l

0.31

100

977

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

1.3

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.20

0.0

3.5

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

1.4

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

1.3

—

(3019198) Lymphocytes [#/volume] in Blood

479

1.12

0.19

5.6

1.93

1.85

e9/l

0.28

429

(3044889) 12 lead EKG panel

650

0.89

0.19

3.5

3.7

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.20

0.18

1.3

1.6

—

(3042936) Bacteria identified in Isolate by Culture

131

0.82

0.18

1.8

2.0

—

(3026361) Erythrocytes [#/volume] in Blood

104

1024

1.34

0.17

20.2

19.9

4.35

4.39

e12/l

0.47

994

(3023368) Bacteria identified in Blood by Culture

216

1.14

0.17

3.5

3.8

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.19

0.17

2.1

1.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.22

0.17

1.6

1.4

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

477

0.90

0.16

7.0

5.3

1.23

mmol/l

0.15

398

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

857

1.14

0.16

5.8

5.6

38.38

39.44

mmol/mol

0.68

785

(40760892) CBC W Ordered Manual Differential panel - Blood

434

1.10

0.15

8.6

6.0

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

228

1.13

0.15

1.8

2.1

3.03

3.09

mg/l

0.05

194

(3022096) Basophils/100 leukocytes in Blood

425

1.10

0.15

5.0

5.6

0.75

0.66

0.46

386

(40758558) Short blood count panel - Blood

258

1.11

0.14

5.5

6.8

—

(3018095) Leukocytes [#/volume] in Urine

341

0.91

0.12

3.3

4.0

51.23

65.57

e6/l

0.12

218

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

913

1.13

0.11

4.5

4.75

4.79

mmol/l

0.15

839

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

271

1.10

0.11

2.1

2.8

1052.51

1169.93

ng/l

0.07

231

(3018418) pH of Serum or Plasma

309

0.92

0.11

5.2

3.5

7.41

7.40

0.48

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

893

1.12

0.11

5.8

5.3

1.67

1.90

mu/l

1.20

813

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

440

1.08

0.10

6.7

4.4

1.23

1.22

mmol/l

0.14

399

(3008898) HLA-B27 [Presence]

1.14

0.10

1.0

1.1

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

904

1.11

0.10

4.5

1.59

mmol/l

0.04

822

(3013650) Neutrophils [#/volume] in Blood by Automated count

551

1.07

0.09

8.1

9.1

3.70

4.06

e9/l

0.71

482

(3014007) Fractional oxyhemoglobin in Arterial blood

1.07

0.09

1.8

5.3

91.60

95.20

—

(3044640) Blood type and Crossmatch panel - Blood

296

0.93

0.08

1.7

2.0

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

865

1.09

0.08

4.0

1.24

1.22

mmol/l

0.14

776

(3000991) Gas panel - Venous blood

1.05

0.08

1.6

4.9

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

108

1.12

0.07

1.8

2.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

345

0.94

0.07

5.0

3.7

14.78

35.32

ng/l

1.10

238

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.05

0.07

1.4

1.8

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.04

0.07

1.4

1.8

—

(3003694) ABO and Rh group [Type] in Blood

264

0.93

0.07

1.8

1.5

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

149

1.09

0.05

2.0

2.8

1.04

1.09

e6/l

0.05

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

219

1.06

0.05

1.4

2.0

—

(40761511) CBC panel - Blood by Automated count

981

1.10

0.04

13.0

12.0

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

279

0.96

0.03

1.6

1.50

1.31

mmol/l

0.42

227

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

321

1.04

0.02

3.3

3.1

—

(3009508) Creatinine [Moles/volume] in Urine

268

0.96

0.02

3.0

2.7

6.21

7.04

mmol/l

0.50

217

(46235355) HIV 1 and 2 tests - Meaningful Use set

174

1.04

0.00

1.7

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

224

1.03

0.00

1.6

0.76

1.08

mg/l

0.77

181

(3012516) Albumin [Mass/volume] in Urine

254

1.03

0.00

2.8

76.10

29.49

mg/l

0.35

153

(1761868) Lipid panel - Serum or Plasma

314

1.03

0.00

3.5

2.9

—

(3019150) Specific gravity of Urine by Refractometry

212

0.99

0.00

3.6

4.2

1.02

kg/l

—

(3020682) Albumin/Creatinine [Ratio] in Urine

271

1.00

0.00

3.6

3.4

7.26

6.99

mg/mmol

0.01

152

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

903

0.98

0.00

5.0

4.6

5.85

5.82

mmol/l

0.10

826

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.06

0.00

1.8

2.1

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

929

1.01

0.00

5.0

5.1

2.73

2.79

mmol/l

0.26

846

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

939

1.01

0.00

12.7

13.4

21.82

20.79

mg/l

0.08

719

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

7.68

—

(3025941) Bacteria identified in Stool by Culture

0.89

-0.00

1.2

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

29.50

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.3

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.2

—

43.60

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.02

-0.00

1.8

5.1

1.04

0.74

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.0

—

(40763324) Parainfluenza virus 1 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3009542) Hematocrit [Volume Fraction] of Blood

103

1024

1.11

-0.00

20.0

19.8

37.68

39.32

1.04

960

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

2.5

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.0

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.5

—

(3000492) Spirometry study

1.00

-0.00

1.6

1.7

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

0.94

-0.00

7.9

3.7

229.88

247.49

u/l

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.6

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

91.78

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.6

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

3.0

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(44813793) Dust mix specific IgE antibody measurement

0.00

-0.00

0.0

1.0

—

(3013727) Leukocytes other/100 leukocytes in Blood

0.00

-0.00

0.0

4.0

—

52.40

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.1

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.86

-0.00

2.4

1.3

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.02

-0.00

1.8

5.1

1.70

1.31

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.97

-0.00

2.3

1.7

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

3.7

—

(3027456) Digoxin [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

4.0

—

0.76

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3035062) Alkaline phosphatase.liver 1 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

52.00

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

-0.00

0.0

1.3

—

366.57

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.2

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

2.6

—

10.74

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

-0.00

0.0

1.6

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3036185) Alkaline phosphatase.liver 2 [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

25.00

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

107.20

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

-0.00

0.0

12.3

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

-0.00

0.0

9.8

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3023199) Leukocytes [#/volume] in Pleural fluid

0.00

-0.00

0.0

1.0

—

1194.80

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3003171) Aldosterone [Moles/volume] in Serum or Plasma --upright

0.00

-0.00

0.0

1.2

—

383.00

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.1

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

1.6

—

(3005082) Progesterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

34.93

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3024263) Appearance of Synovial fluid

0.00

-0.00

0.0

1.0

—

(3030558) Cytomegalovirus DNA [Units/volume] (viral load) in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(40763470) Parainfluenza virus 4 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3020013) Alkaline phosphatase.intestinal [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

10.50

—

(21494755) Public health laboratory ask at order entry panel

0.89

-0.00

1.5

1.3

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

1.6

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.6

—

2.01

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

7.34

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

3.0

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.4

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3012441) Differential panel - Pleural fluid

0.00

-0.00

0.0

1.0

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

1.1

—

30.31

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

240

1.00

-0.00

1.1

1.2

0.42

1.74

u/ml

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

96.00

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.1

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

-0.00

0.0

1.0

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.2

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

0.90

-0.00

2.1

4.6

100.89

103.83

mmol/l

—

(3027953) Aldolase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

4.89

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

-0.00

0.0

1.8

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(3028772) Osteocalcin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

27861.00

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_FEMALE_GEN_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_FEMALE_GEN_NOS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_FEMALE_GEN_NOS – Benign neoplasm: Female genital organ, unspecified

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Female genital organ, unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints