Benign neoplasm: Female genital organ, unspecified

CD2_BENIGN_FEMALE_GEN_NOS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D28.9&
  • Hospital discharge: ICD-9 221[8-9]
  • Hospital discharge: ICD-8 2219
  • Cause of death: ICD-10 D28.9&
  • Cause of death: ICD-9 221[8-9]
  • Cause of death: ICD-8 2219

2 out of 7 registries used, show all original rules.

108

4. Check minimum number of events

None

108

5. Include endpoints

None

108

6. Filter based on genotype QC (FinnGen only)

108

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D28
Name in latin
Neoplasma benignum organi genitalis feminini non specificati

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 995 995 -
Only index persons 837 837 -
Unadjusted period prevalence (%)
Whole population 0.03 0.03 -
Only index persons 0.03 0.03 -
Median age at first event (years)
Whole population - 44.49 -
Only index persons - 42.31 -

-FinnGen-

Key figures

All Female Male
Number of individuals 108 108 -
Unadjusted period prevalence (%) 0.04 0.04 -
Median age at first event (years) 39.04 39.04 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
95
Matched controls
950
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D28.9
ICD-10 Finland
Benign neoplasm: Female genital organ, unspecified
+∞
65.3
55
*
22199
ICD-8 Finland
Benign neoplasm of other female genital organs, Unspecified site
+∞
30.9
28
*
2218X
ICD-9 Finland
Benign neoplasm of other female genital organs, Other specified sites of female genital organs
+∞
9.5
9
*
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
20.5
7.8
11
6

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
18
83
2.40
2.58
5.0
3.7
—
—
—
0
0
6
11
5.70
2.58
1.5
2.7
90.7
89.2
%
—
6
11
21
110
2.13
2.25
1.8
1.9
—
—
—
0
0
80
663
1.80
1.90
3.7
4.6
—
—
—
0
0
29
181
1.82
1.89
2.1
1.8
440.5
492.9
pmol/l
0.53
22
149
6
17
3.67
1.86
1.5
3.8
8.7
9.2
kpa
—
6
17
6
17
3.67
1.86
1.5
3.8
4.8
5.0
kpa
—
6
17
9
43
2.19
1.34
2.7
3.3
—
—
—
0
0
35
257
1.54
1.21
4.3
4.2
0.0
0.0
estimate
0.00
15
95
0
35
0.00
1.17
0.0
1.5
—
0.2
—
0
35
0
36
0.00
1.16
0.0
1.5
—
1.2
—
0
36
5
22
2.33
1.04
1.8
1.5
—
—
—
0
0
57
478
1.41
0.96
4.5
4.0
0.0
0.0
estimate
0.00
15
91
17
111
1.63
0.95
1.2
1.8
141.8
118.0
ug/g
0.15
12
87
17
114
1.58
0.86
1.2
1.2
—
—
—
0
0
30
229
1.43
0.84
1.6
1.5
27.2
23.2
nmol/l
0.50
24
184
21
150
1.50
0.81
1.5
1.6
—
—
—
0
0
10
59
1.77
0.79
5.2
2.9
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
55
473
1.33
0.73
6.0
5.5
0.0
0.0
estimate
0.00
15
92
37
300
1.35
0.72
2.2
2.2
55.4
54.0
u/l
0.10
32
270
18
128
1.49
0.71
1.2
1.2
—
—
—
0
0
55
475
1.32
0.70
3.9
3.9
0.0
0.0
estimate
0.00
15
95
35
283
1.35
0.69
4.8
3.5
—
—
—
0
0
34
275
1.34
0.67
5.6
3.7
—
—
—
0
0
5
28
1.82
0.67
1.0
1.5
337.6
153.0
ug/l
—
5
23
15
104
1.51
0.67
1.7
1.6
—
—
—
0
0
14
97
1.51
0.62
1.4
1.4
—
—
—
0
0
41
345
1.30
0.61
3.0
3.2
2.4
2.4
mmol/l
0.05
34
305
14
98
1.49
0.60
1.1
1.3
—
—
—
0
0
48
414
1.29
0.59
10.7
9.3
0.0
0.0
e9/l
0.50
43
340
9
61
1.52
0.55
1.1
1.3
—
—
—
0
0
6
38
1.61
0.55
1.8
1.5
—
—
—
0
0
12
83
1.50
0.54
2.7
4.2
1.2
1.2
mmol/l
0.31
12
73
39
332
1.27
0.52
2.5
3.1
—
—
—
0
0
48
420
1.26
0.51
3.2
2.7
88.0
78.1
ug/l
0.14
41
389
7
45
1.59
0.50
1.3
2.1
—
—
—
0
0
7
45
1.59
0.50
1.4
4.2
24.5
25.5
mmol/l
—
7
45
34
288
1.26
0.47
4.5
5.3
—
—
—
0
0
25
204
1.29
0.46
1.5
1.5
2.0
2.5
g/l
1.11
16
113
25
206
1.28
0.43
2.9
3.9
—
—
—
0
0
12
88
1.41
0.42
3.9
3.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
71
659
1.23
0.41
4.8
4.8
—
341.8
—
0
12
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
2.1
—
—
—
0
0
23
190
1.27
0.39
1.4
1.3
37.5
35.1
iu/ml
—
6
64
76
713
1.22
0.38
4.1
4.3
11.1
12.3
mm/h
0.54
68
637
13
100
1.34
0.35
1.6
1.4
—
—
—
0
0
6
86
0.68
0.34
1.0
1.1
—
—
—
0
0
14
110
1.31
0.34
1.3
1.3
—
—
—
0
0
7
98
0.69
0.32
10.9
4.8
4.8
1.6
mmol/l
—
7
83
7
51
1.40
0.32
6.0
1.8
—
—
—
0
0
48
437
1.18
0.32
4.4
5.5
53.3
57.6
%
1.25
41
404
80
760
1.20
0.31
4.7
4.4
14.7
14.7
pmol/l
0.04
74
686
11
140
0.76
0.30
1.4
1.3
—
565.7
titre
—
0
35
28
245
1.19
0.28
3.1
3.3
0.6
0.4
e6/l
0.26
23
170
22
188
1.21
0.28
1.2
1.3
1.3
9.1
u/ml
—
5
68
50
540
0.86
0.28
4.7
4.0
6.5
6.5
mmol/l
0.00
44
494
47
431
1.16
0.28
4.4
5.6
3.3
2.6
%
0.99
40
393
25
217
1.20
0.27
2.7
2.7
328.1
6515.2
umol/l
1.30
16
185
50
461
1.16
0.27
5.2
5.5
0.6
0.5
e9/l
0.42
41
397
50
462
1.15
0.26
5.2
5.6
0.0
0.0
e9/l
0.23
41
400
21
180
1.21
0.26
2.6
1.7
1191.0
1193.8
nmol/l
0.00
13
135
9
76
1.20
0.25
1.3
1.4
—
—
—
0
0
48
444
1.15
0.24
4.5
5.7
31.3
28.2
%
0.76
40
406
43
395
1.15
0.24
2.2
1.9
99.8
99.3
pmol/l
0.03
21
175
10
79
1.29
0.23
2.1
3.1
—
—
—
0
0
5
41
1.23
0.22
1.6
2.3
26.5
24.7
mmol/l
—
5
41
38
348
1.14
0.22
7.9
6.7
1.0
1.2
inr
2.59
13
104
5
42
1.20
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
20.0
—
0
10
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
3.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
2.5
—
—
—
0
0
51
478
1.13
0.20
5.4
5.6
0.2
0.2
e9/l
0.62
43
420
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
6
52
1.16
0.19
1.8
3.2
4.8
5.2
kpa
—
6
46
46
430
1.12
0.19
2.4
2.0
—
—
—
0
0
31
338
0.88
0.18
3.3
4.1
53.2
66.2
e6/l
0.10
24
216
5
66
0.75
0.17
1.6
1.3
—
—
—
0
0
103
1015
1.32
0.17
19.8
19.9
4.3
4.4
e12/l
0.41
98
985
46
432
1.11
0.17
4.7
5.9
8.1
8.2
%
0.06
39
398
28
306
0.89
0.17
5.2
3.4
7.4
7.4
ph
—
10
63
50
472
1.11
0.17
5.3
5.6
1.9
1.8
e9/l
0.18
41
420
25
226
1.14
0.17
1.8
2.1
3.0
3.1
mg/l
0.05
18
193
11
129
0.84
0.15
1.8
2.0
—
—
—
0
0
24
218
1.13
0.15
7.7
4.9
—
—
—
0
0
87
848
1.13
0.15
5.8
5.6
38.5
39.4
mmol/mol
0.60
79
776
14
122
1.17
0.14
1.4
1.3
—
—
—
0
0
27
248
1.12
0.14
3.2
3.2
—
—
—
0
0
62
644
0.91
0.14
3.5
3.7
—
—
—
0
0
32
340
0.92
0.11
5.1
3.7
15.2
35.6
ng/l
1.07
17
235
44
421
1.08
0.10
4.6
5.7
0.7
0.7
%
0.40
37
383
5
47
1.07
0.09
1.8
5.3
91.6
95.2
%
—
5
47
36
378
0.93
0.09
3.3
3.8
—
—
—
0
0
92
905
1.11
0.09
4.5
4.5
4.7
4.8
mmol/l
0.13
84
831
90
885
1.10
0.09
5.8
5.3
1.7
1.9
mu/l
1.13
85
806
23
215
1.09
0.08
3.6
3.8
—
—
—
0
0
28
296
0.93
0.08
1.7
2.0
—
—
—
0
0
91
896
1.10
0.08
4.6
4.5
1.6
1.6
mmol/l
0.01
83
814
7
67
1.05
0.08
1.6
4.9
—
—
—
0
0
27
255
1.08
0.08
5.7
6.8
—
—
—
0
0
25
265
0.93
0.08
3.0
2.7
5.6
7.0
mmol/l
1.78
18
211
56
545
1.06
0.06
7.9
9.1
3.7
4.1
e9/l
0.75
47
476
87
857
1.08
0.06
4.0
4.0
1.2
1.2
mmol/l
0.19
77
769
25
263
0.94
0.06
1.8
1.5
—
—
—
0
0
45
436
1.06
0.06
6.7
4.4
1.2
1.2
mmol/l
0.06
40
392
10
90
1.12
0.05
1.7
1.5
—
—
—
0
0
26
269
0.96
0.03
4.2
3.6
7.8
7.1
mg/mmol
0.04
14
150
32
311
1.04
0.03
3.5
2.9
—
—
—
0
0
98
973
1.08
0.02
12.9
12.1
—
—
—
0
0
18
173
1.05
0.01
1.7
1.7
—
—
—
0
0
23
223
1.04
0.01
1.6
1.6
0.8
1.1
mg/l
0.77
17
181
27
277
0.97
0.01
1.6
1.6
1.5
1.3
mmol/l
0.42
19
225
21
212
0.99
0.00
3.6
4.2
1.0
1.0
kg/l
—
6
29
25
252
0.99
0.00
2.9
2.8
81.6
29.7
mg/l
0.37
13
150
89
895
0.97
0.00
5.1
4.6
5.9
5.8
mmol/l
0.11
82
819
24
239
1.01
0.00
1.1
1.2
0.4
1.7
u/ml
—
5
58
84
836
1.02
0.00
12.7
13.6
36.3
39.3
%
1.12
53
599
92
921
0.99
0.00
5.0
5.1
2.7
2.8
mmol/l
0.22
84
837
93
931
0.99
0.00
12.2
13.4
22.1
20.8
mg/l
0.11
75
715
5
56
0.89
0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
30.3
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
2.0
—
0
7
0
7
0.00
0.00
0.0
1.3
—
34.9
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1194.8
—
0
5
5
49
1.02
0.00
1.8
5.1
1.7
1.3
%
—
5
49
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
70
1.00
0.00
1.6
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
52.4
—
0
5
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.8
5.1
1.0
0.7
%
—
5
49
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
7.3
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
4.0
—
0.8
—
0
8
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
7.7
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
12.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
10.7
—
0
5
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_FEMALE_GEN_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_FEMALE_GEN_NOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_FEMALE_GEN_NOS – Benign neoplasm: Female genital organ, unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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