Benign neoplasm: Vulva

CD2_BENIGN_VAGINA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D28.0&
  • Hospital discharge: ICD-8 2212
  • Cause of death: ICD-10 D28.0&
  • Cause of death: ICD-8 2212

2 out of 7 registries used, show all original rules.

754

4. Check minimum number of events

None

754

5. Include endpoints

None

754

6. Filter based on genotype QC (FinnGen only)

754

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D28
Name in latin
Neoplasma benignum vulvae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5127 5127 -
Only index persons 4729 4729 -
Unadjusted period prevalence (%)
Whole population 0.15 0.15 -
Only index persons 0.17 0.17 -
Median age at first event (years)
Whole population - 42.27 -
Only index persons - 41.49 -

-FinnGen-

Key figures

All Female Male
Number of individuals 754 754 -
Unadjusted period prevalence (%) 0.26 0.26 -
Median age at first event (years) 41.68 41.68 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
678
Matched controls
6780
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D28.0
ICD-10 Finland
Benign neoplasm: Vulva
+∞
323.0
457
*
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
82.1
160.0
177
29
22120
ICD-8 Finland
Benign neoplasm of other female genital organs, Vulva
+∞
131.6
122
*
22121
ICD-8 Finland
NA
+∞
51.7
49
*
22122
ICD-8 Finland
NA
+∞
50.7
48
*
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
27.9
31.0
42
16
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
6.2
25.2
70
123
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.6
12.7
101
434
8473
FHL
Guinea pig or gland excision
25.5
11.2
15
6
N75.0
ICD-10 Finland
Cyst of Bartholin gland
8.5
9.6
20
24
J01DA01
ATC
[U] cefalexin; systemic
1.7
9.1
438
3546
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.1
8.5
102
533
R01AD09
ATC
mometasone; nasal
1.6
8.0
325
2483
N90.7
ICD-10 Finland
Vulvar cyst
15.2
7.7
12
8
LFW96
NOMESCO Finland
Other operation on vulva or perineum
80.9
7.4
8
*
A02BC05
ATC
esomeprazole; systemic
1.6
7.1
289
2188
ULA02
NOMESCO Finland
Kolposcopy
2.0
7.0
91
489
62212
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Bartholinitis acuta
13.9
6.9
11
8
LFC00
NOMESCO Finland
Partial excision of vulva
13.9
6.9
11
8
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.9
250
1835
X01
ICPC
Genital pain female
6.9
6.5
15
22
R03AC02
ATC
salbutamol; inhalant
1.5
6.4
368
2988

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
364
2871
1.52
7.26
2.3
2.1
—
—
—
0
0
113
699
1.73
6.18
4.6
3.8
—
—
—
0
0
129
849
1.63
5.56
1.3
1.2
—
—
—
0
0
557
5020
1.42
4.25
4.4
4.2
12.7
12.6
mm/h
0.10
514
4619
360
3039
1.35
4.06
5.2
5.2
1.2
1.2
mmol/l
0.74
318
2737
297
2442
1.36
3.94
8.5
8.1
1.2
1.2
inr
0.47
72
715
565
5137
1.40
3.84
7.2
7.1
78.7
77.1
u/l
0.35
529
4798
40
214
1.92
3.56
2.2
2.0
2877.3
2548.7
u/l
0.04
14
88
705
6730
1.73
3.47
16.1
15.0
3.9
3.9
mmol/l
0.03
688
6525
17
64
2.69
3.41
1.5
1.2
—
—
—
0
0
385
3345
1.31
3.31
6.7
5.9
1.2
1.2
mmol/l
0.32
319
2825
160
1221
1.39
3.30
1.7
1.7
1273.0
1215.4
nmol/l
0.25
117
887
254
2091
1.32
3.20
2.2
2.1
—
—
—
0
0
702
6716
1.66
3.13
16.0
14.9
139.7
139.7
mmol/l
0.16
687
6528
250
2060
1.32
3.12
2.5
2.3
55.0
56.8
u/l
0.33
232
1873
93
651
1.49
3.05
1.5
1.4
—
—
—
0
0
200
1601
1.34
3.04
2.5
2.0
—
—
—
0
0
105
757
1.45
2.97
1.3
1.3
—
—
—
0
0
133
1004
1.39
2.92
1.2
1.2
—
—
—
0
0
19
84
2.29
2.79
1.5
1.2
—
—
nmol/l
—
0
0
167
1320
1.34
2.74
1.3
1.3
15.1
33.2
iu/ml
4.61
49
433
16
66
2.46
2.72
1.8
2.8
—
—
—
0
0
6
10
6.04
2.70
3.7
1.3
97.0
88.8
ng/l
—
6
10
67
450
1.54
2.69
3.4
3.1
4.0
4.0
e9/l
0.00
49
348
87
618
1.46
2.67
2.1
2.1
367.1
372.3
nmol/l
0.08
75
570
317
2745
1.27
2.59
2.1
2.0
103.1
98.2
pmol/l
0.79
145
1279
15
62
2.45
2.55
7.7
6.2
13.0
12.5
mg/l
0.13
15
55
681
6516
1.47
2.51
14.5
13.3
18.5
20.5
mg/l
1.01
552
5094
93
678
1.42
2.49
1.8
1.6
—
—
—
0
0
231
1938
1.28
2.42
3.6
3.6
—
—
—
0
0
411
3689
1.25
2.41
3.9
4.2
6.8
6.6
mmol/l
0.95
382
3416
388
3461
1.25
2.40
5.1
5.5
10.6
10.3
umol/l
0.15
363
3266
34
199
1.74
2.36
2.9
3.0
—
—
—
0
0
192
1581
1.29
2.32
2.4
2.4
9626.0
4557.3
umol/l
0.55
168
1353
92
681
1.40
2.28
2.0
2.2
7.0
6.6
umol/l
0.07
82
574
159
1281
1.31
2.27
1.3
1.3
6.5
10.9
u/ml
0.58
59
470
714
6927
1.58
2.13
11.2
10.3
23.3
23.5
u/l
0.13
687
6667
61
425
1.47
2.10
1.7
1.3
—
—
—
0
0
39
246
1.62
2.08
2.1
3.4
—
—
—
0
0
353
3150
1.23
2.07
3.8
3.8
—
—
—
0
0
234
2002
1.24
2.03
1.8
2.1
118.9
146.3
u/l
1.34
216
1886
255
2204
1.24
2.02
7.0
5.5
—
—
—
0
0
19
97
1.98
2.01
1.4
1.2
0.6
0.6
nmol/l
0.13
19
91
77
567
1.40
1.98
3.1
3.2
109.1
78.9
ng/l
1.30
62
492
18
91
2.00
1.96
1.4
1.2
—
—
—
0
0
589
5570
1.26
1.90
5.0
4.5
14.6
14.8
pmol/l
1.72
535
5078
225
1931
1.24
1.88
3.3
2.9
6.1
6.4
mmol/l
0.44
182
1617
487
4527
1.21
1.78
5.3
4.8
1478.2
2410.4
e6/l
—
6
65
119
956
1.29
1.74
1.3
1.3
784.3
588.5
titre
0.27
23
223
33
210
1.60
1.74
2.5
3.6
24.9
25.1
mmol/l
0.15
27
200
21
118
1.80
1.71
1.3
1.7
—
—
—
0
0
374
3403
1.20
1.68
6.7
5.8
0.2
0.2
e9/l
0.09
324
2979
349
3156
1.20
1.68
6.8
5.8
27.8
28.7
%
1.03
327
2914
496
4632
1.21
1.67
5.3
4.6
—
—
—
0
0
212
1829
1.22
1.67
3.4
3.1
411.3
431.2
mg/l
0.02
117
1019
659
6345
1.31
1.66
6.0
5.4
1.8
2.1
mu/l
0.70
609
5818
368
3349
1.19
1.64
6.4
5.5
1.9
1.9
e9/l
0.28
321
2941
5
14
3.59
1.62
1.0
1.4
—
—
—
0
0
93
731
1.31
1.61
20.1
22.5
1.2
1.2
inr
0.05
13
91
7
26
2.71
1.58
1.0
1.2
—
—
—
0
0
707
6888
1.42
1.56
16.1
15.4
71.4
69.5
umol/l
0.71
707
6888
13
64
2.05
1.55
1.6
1.5
—
—
—
0
0
360
3282
1.19
1.54
6.7
5.5
0.0
0.0
e9/l
0.10
312
2818
344
3124
1.19
1.54
6.6
5.5
58.2
56.8
%
1.45
321
2897
220
1923
1.20
1.50
4.0
3.7
15.9
6.9
mg/mmol
1.02
126
1071
697
6780
1.37
1.50
14.2
12.5
—
—
—
0
0
328
2972
1.18
1.50
6.8
5.7
0.7
0.7
%
1.13
307
2736
266
2371
1.19
1.46
3.3
3.4
24.7
43.1
ng/l
0.60
156
1582
5
16
3.14
1.44
1.0
1.0
—
—
—
0
0
357
3268
1.18
1.42
6.4
5.5
0.6
0.5
e9/l
0.28
307
2807
641
6176
1.25
1.42
4.1
3.9
1.3
1.2
mmol/l
0.61
584
5601
628
6041
1.24
1.39
5.9
5.6
40.1
39.3
mmol/mol
1.34
575
5567
16
89
1.82
1.38
1.1
1.1
10.8
1.9
u/ml
—
8
41
337
3087
1.17
1.30
7.1
5.9
8.4
8.3
%
0.22
316
2859
204
1794
1.19
1.29
2.4
2.8
1129.5
982.5
ng/l
0.19
165
1500
731
7188
1.56
1.29
22.2
20.0
263.5
261.9
e9/l
0.28
714
7011
15
84
1.80
1.28
1.1
1.1
1.3
0.7
u/ml
—
6
32
731
7189
1.55
1.27
22.1
19.9
91.0
91.0
fl
0.05
725
7082
335
3072
1.16
1.26
6.7
5.6
2.8
2.7
%
0.25
312
2828
731
7190
1.55
1.26
22.2
20.0
4.4
4.4
e12/l
0.19
714
6992
731
7190
1.55
1.26
22.1
19.9
30.1
30.2
pg
0.30
725
7082
184
1608
1.19
1.25
2.3
2.2
2.9
3.1
mg/l
0.26
160
1350
731
7191
1.54
1.24
22.3
20.1
131.7
131.7
g/l
0.01
725
7085
731
7191
1.54
1.24
22.2
20.0
6.6
6.5
e9/l
0.51
711
6990
8
36
2.23
1.24
2.6
3.3
—
—
—
0
0
43
314
1.39
1.23
1.4
2.0
—
—
—
0
0
262
2363
1.17
1.22
3.4
3.1
—
—
—
0
0
309
2824
1.16
1.21
4.9
4.1
35.6
35.8
g/l
0.24
284
2607
109
909
1.23
1.20
1.6
1.5
—
—
—
0
0
662
6428
1.24
1.18
4.6
4.4
1.6
1.6
mmol/l
0.52
607
5891
70
556
1.29
1.16
1.5
1.5
—
—
—
0
0
8
39
2.06
1.15
3.0
6.5
—
—
—
0
0
30
208
1.46
1.14
2.4
3.0
0.4
0.3
g/l
0.33
13
64
182
1604
1.18
1.12
1.3
1.3
0.5
1.5
u/ml
3.47
49
396
7
30
2.35
1.12
2.6
2.5
—
—
—
0
0
10
51
1.97
1.11
1.1
1.2
—
—
—
0
0
22
144
1.54
1.09
1.6
1.7
4759.3
16663.1
e6/l
1.46
12
102
41
304
1.37
1.09
1.1
1.2
—
—
—
0
0
665
6470
1.24
1.09
4.6
4.4
4.8
4.8
mmol/l
1.53
612
5962
9
163
0.55
1.09
6.1
4.7
—
—
—
0
0
92
762
1.24
1.09
6.4
4.1
1.1
1.0
mmol/l
0.45
83
693
15
89
1.70
1.08
1.3
1.2
—
—
—
0
0
411
3857
1.14
1.07
8.2
8.8
4.2
3.9
e9/l
1.19
360
3374
104
875
1.22
1.07
2.1
2.0
85.1
121.9
ug/g
1.11
83
670
14
82
1.72
1.05
2.0
1.4
26.0
42.3
mu/l
0.47
14
75
61
483
1.29
1.05
1.2
1.4
—
—
—
0
0
7
34
2.07
1.03
4.3
1.9
—
—
—
0
0
321
2971
1.14
1.01
3.2
2.8
81.5
90.4
ug/l
0.81
293
2726
11
61
1.82
0.99
2.9
2.6
—
—
—
0
0
71
580
1.25
0.97
1.2
1.1
—
—
—
0
0
8
43
1.87
0.87
1.1
1.4
—
2351.2
—
0
8
17
112
1.53
0.85
1.1
1.6
—
—
—
0
0
77
645
1.22
0.85
3.5
2.6
1.9
1.9
%
0.06
62
562
674
6595
1.21
0.85
5.2
5.0
2.8
2.8
mmol/l
1.12
622
6050
6
31
1.94
0.84
3.0
3.7
—
—
—
0
0
71
591
1.22
0.84
2.3
2.0
0.2
0.2
g/l
0.34
65
567
8
46
1.75
0.82
1.4
1.2
1.1
1.7
nmol/l
—
8
37
16
105
1.54
0.82
1.0
1.0
—
14.4
—
0
8
109
947
1.18
0.82
2.8
2.2
12.7
12.7
umol/l
0.02
104
866
15
97
1.56
0.82
1.3
1.1
5.3
2.0
u/ml
—
7
34
10
58
1.73
0.80
1.3
1.1
—
—
—
0
0
157
1409
1.14
0.78
1.6
1.7
64341544.3
15157244.4
pmol/l
0.35
129
1148
29
218
1.34
0.76
1.8
1.9
6.9
2.3
ug/l
0.50
24
193
527
5450
0.89
0.75
18.1
16.4
13.8
13.7
%
1.00
515
5330
36
457
0.78
0.75
2.5
2.5
—
—
—
0
0
657
6430
1.17
0.73
4.7
4.5
5.9
5.8
mmol/l
0.53
600
5823
151
1360
1.14
0.71
1.4
1.5
2.2
2.2
g/l
0.10
77
771
9
57
1.59
0.71
2.2
1.5
—
—
—
0
0
9
57
1.59
0.71
2.2
1.5
—
—
—
0
0
9
57
1.59
0.71
2.2
1.5
—
—
—
0
0
9
57
1.59
0.71
2.2
1.5
—
—
—
0
0
15
101
1.49
0.70
1.1
1.0
—
—
—
0
0
99
866
1.16
0.70
2.7
2.2
2.4
2.4
g/l
0.18
93
800
118
1048
1.15
0.69
1.8
1.7
—
—
—
0
0
5
27
1.86
0.68
2.0
1.8
—
—
—
0
0
18
127
1.43
0.68
3.2
2.2
—
—
—
0
0
7
43
1.63
0.67
1.6
1.2
—
—
—
0
0
12
78
1.55
0.66
2.8
1.6
38.5
56.7
u/ml
0.12
12
73
5
29
1.73
0.64
1.0
1.0
—
—
—
0
0
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
113
1008
1.14
0.63
3.3
2.7
0.8
0.8
mmol/l
0.49
94
937
167
1528
1.12
0.62
1.8
1.7
0.9
1.0
mg/l
0.10
124
1147
10
63
1.60
0.62
1.3
1.6
—
—
—
0
0
5
30
1.67
0.61
4.0
1.6
—
—
—
0
0
131
1447
0.89
0.61
4.2
4.3
1.0
1.0
kg/l
0.34
17
218
0
20
0.00
0.60
0.0
1.4
—
—
—
0
0
0
20
0.00
0.60
0.0
2.3
—
—
—
0
0
174
1600
1.11
0.59
3.7
3.3
96.7
95.2
%
0.36
168
1551
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
22
167
1.33
0.57
1.7
2.3
—
—
—
0
0
28
221
1.28
0.56
3.7
4.3
—
—
—
0
0
8
126
0.63
0.54
5.5
2.8
8.7
8.0
kpa
—
8
119
6
38
1.58
0.54
1.5
1.8
8.1
9.6
ug/l
—
6
31
6
38
1.58
0.54
3.2
2.8
—
—
—
0
0
14
99
1.42
0.54
1.4
1.2
—
—
—
0
0
55
470
1.18
0.54
3.9
2.7
74.6
73.3
e9/l
0.10
48
352
88
781
1.14
0.54
1.7
1.3
—
—
—
0
0
257
2424
1.09
0.53
3.3
3.3
2.4
2.4
mmol/l
0.13
205
2105
9
135
0.66
0.52
1.2
1.3
—
—
—
0
0
90
804
1.14
0.51
2.5
2.3
20.9
21.5
%
0.17
72
680
11
75
1.47
0.51
1.4
1.1
—
—
—
0
0
12
84
1.44
0.49
1.2
1.1
—
—
—
0
0
70
616
1.15
0.49
1.4
1.4
—
—
—
0
0
77
683
1.14
0.49
3.7
3.8
3.0
10.3
ug/l
3.52
64
549
11
155
0.71
0.48
1.0
1.2
3.8
3.8
mmol/l
0.09
11
145
40
337
1.20
0.47
1.1
1.1
—
105.6
—
0
8
67
758
0.87
0.47
1.9
1.8
—
—
—
0
0
49
567
0.85
0.46
3.1
3.5
1.2
1.2
mmol/l
0.57
42
486
53
459
1.17
0.46
2.7
3.2
—
—
—
0
0
14
103
1.37
0.45
1.2
1.6
—
—
—
0
0
57
498
1.16
0.45
1.4
1.2
—
—
—
0
0
7
51
1.38
0.44
1.1
1.2
—
—
—
0
0
13
95
1.37
0.44
1.0
1.0
—
—
—
0
0
51
443
1.16
0.44
6.1
6.4
—
—
—
0
0
5
31
1.62
0.43
1.8
3.5
862.0
1047.7
u/ml
—
5
31
66
587
1.14
0.42
1.5
1.5
—
—
—
0
0
13
96
1.36
0.41
1.5
1.2
—
—
—
0
0
45
391
1.16
0.39
1.9
1.8
—
—
—
0
0
7
105
0.66
0.39
1.1
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
2.5
—
—
—
0
0
62
553
1.13
0.38
1.2
1.2
174.2
165.4
iu/ml
0.07
22
226
5
37
1.35
0.37
2.4
2.3
1.4
2.3
ug/l
—
5
30
5
37
1.35
0.37
1.0
1.2
—
—
—
0
0
10
72
1.39
0.37
2.7
2.1
93.3
89.8
%
—
10
72
5
78
0.64
0.35
1.4
1.8
—
—
—
0
0
5
79
0.63
0.35
1.4
2.0
—
—
—
0
0
6
43
1.40
0.35
1.0
1.5
—
—
—
0
0
127
1186
1.09
0.34
3.7
3.7
242.1
365.1
ng/l
0.25
86
883
56
502
1.12
0.33
1.4
1.3
—
—
—
0
0
196
1864
1.07
0.33
2.9
3.1
90.7
54.9
e6/l
0.26
145
1401
6
87
0.69
0.33
2.2
2.8
—
—
—
0
0
6
47
1.28
0.32
1.2
1.1
—
—
—
0
0
181
1720
1.07
0.31
2.9
3.0
0.3
0.4
e6/l
0.54
129
1279
57
515
1.12
0.30
3.2
3.8
0.0
0.1
%
2.51
13
122
237
2275
1.06
0.30
3.2
3.6
85.2
92.2
e6/l
0.08
153
1536
10
75
1.34
0.30
2.1
1.4
280.9
274.6
mosm/kgh2o
—
10
53
12
93
1.30
0.30
1.0
1.0
—
—
—
0
0
138
1461
0.93
0.30
4.4
4.4
—
—
—
0
0
18
148
1.22
0.29
1.2
1.2
—
—
—
0
0
41
364
1.13
0.29
3.9
4.7
—
—
—
0
0
8
106
0.75
0.29
1.3
1.3
—
—
—
0
0
54
489
1.11
0.28
3.4
3.9
0.0
0.9
%
0.50
13
101
8
62
1.29
0.28
1.6
1.2
—
—
—
0
0
30
341
0.87
0.26
2.6
3.5
—
—
—
0
0
5
73
0.68
0.26
1.4
2.1
31.2
31.5
pg
—
5
73
17
203
0.83
0.26
1.5
1.3
157.4
233.8
miu/ml
—
10
97
9
72
1.25
0.25
1.1
1.1
—
88.8
—
0
5
61
560
1.10
0.25
1.3
1.4
—
—
—
0
0
15
123
1.22
0.25
1.2
1.7
—
—
—
0
0
9
73
1.24
0.25
1.6
2.9
—
—
—
0
0
32
361
0.88
0.25
1.3
1.4
—
—
—
0
0
94
882
1.08
0.24
2.0
1.9
—
—
—
0
0
9
77
1.17
0.24
1.2
1.0
—
—
—
0
0
5
40
1.25
0.22
1.0
1.0
526.2
362.6
ng/l
—
5
26
47
513
0.91
0.22
3.3
3.5
—
—
—
0
0
17
144
1.18
0.22
2.7
2.0
130.0
128.1
g/l
—
10
107
5
41
1.22
0.22
1.0
1.0
795.0
680.1
ng/l
—
5
27
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
212
2050
1.05
0.21
3.6
3.6
7.4
7.4
ph
0.13
41
379
0
12
0.00
0.21
0.0
4.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
214
2209
0.96
0.20
2.6
2.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
54
500
1.09
0.20
3.3
3.7
0.7
0.7
%
0.01
12
96
129
1234
1.05
0.20
2.7
2.6
464.0
511.0
mosm/kgh2o
1.85
105
1045
184
1777
1.05
0.19
3.7
3.6
—
—
—
0
0
15
127
1.18
0.19
5.6
2.2
—
—
—
0
0
6
51
1.18
0.19
1.2
1.2
—
—
—
0
0
177
1709
1.05
0.19
2.8
2.9
—
—
—
0
0
25
222
1.13
0.19
4.4
5.0
2.0
1.5
%
0.81
25
208
14
118
1.19
0.19
4.4
2.3
16.7
15.9
%
—
6
62
14
118
1.19
0.19
6.3
7.3
10.7
11.0
mmol/l
0.15
14
106
14
118
1.19
0.19
6.4
7.3
104.1
105.4
mmol/l
0.46
14
106
252
2588
0.96
0.19
3.5
3.6
—
—
—
0
0
6
52
1.16
0.19
1.3
1.2
506.0
372.8
nmol/l
—
6
47
342
3350
1.04
0.19
3.8
3.9
0.0
0.0
estimate
0.80
73
594
15
174
0.86
0.18
1.1
1.1
—
—
—
0
0
7
61
1.15
0.17
2.9
2.0
—
—
—
0
0
25
278
0.90
0.17
5.9
8.5
—
—
—
0
0
13
152
0.85
0.17
1.5
1.5
—
—
—
0
0
8
69
1.16
0.16
1.1
1.1
—
—
—
0
0
8
70
1.14
0.16
1.3
1.5
—
—
—
0
0
16
139
1.15
0.16
3.2
3.7
25.7
18.6
mg/l
—
9
84
13
151
0.86
0.16
1.5
1.4
—
—
—
0
0
48
513
0.93
0.15
2.8
2.8
65.3
67.1
g/l
0.62
42
467
10
83
1.21
0.15
1.0
1.5
—
22.4
—
0
5
22
244
0.90
0.15
1.0
1.2
—
—
—
0
0
338
3324
1.03
0.14
5.2
5.3
0.0
0.0
estimate
0.50
73
603
21
233
0.90
0.14
1.0
1.1
—
—
—
0
0
13
149
0.87
0.13
1.5
1.4
—
—
—
0
0
8
100
0.80
0.13
4.6
2.5
—
—
—
0
0
13
113
1.15
0.13
7.1
3.4
—
—
—
0
0
23
209
1.10
0.13
2.7
1.8
9.0
4.8
iu/l
—
7
69
181
1766
1.03
0.12
4.0
4.2
0.0
0.0
estimate
1.08
72
598
15
168
0.89
0.11
1.0
1.3
439.1
487.3
mg/l
0.42
15
158
38
404
0.94
0.11
1.1
1.3
—
—
—
0
0
57
544
1.05
0.11
3.2
3.8
0.4
1.0
%
1.34
13
136
25
270
0.92
0.10
1.3
1.3
—
—
—
0
0
46
484
0.95
0.10
2.0
2.3
4.4
6.1
ug/l
0.85
37
416
11
96
1.15
0.10
1.3
1.1
—
—
—
0
0
5
44
1.14
0.10
1.6
1.2
—
—
—
0
0
5
47
1.06
0.09
1.8
1.3
1.2
1.0
g/l
—
5
47
34
360
0.94
0.09
2.8
2.4
—
—
—
0
0
46
481
0.95
0.08
5.7
3.0
4.4
4.5
pmol/l
0.42
41
420
12
107
1.12
0.08
8.2
1.7
—
—
—
0
0
294
2904
1.02
0.08
9.4
9.0
0.0
0.0
e9/l
2.96
240
2369
5
61
0.82
0.08
1.0
1.2
—
—
—
0
0
6
73
0.82
0.07
1.8
2.8
—
—
—
0
0
8
74
1.08
0.07
1.1
1.7
—
—
—
0
0
135
1325
1.02
0.07
2.5
2.5
5.7
8.1
e6/l
1.57
115
1170
14
128
1.10
0.06
3.4
1.4
—
—
—
0
0
11
99
1.11
0.06
1.2
1.3
—
—
—
0
0
9
105
0.86
0.06
1.0
1.1
—
—
—
0
0
17
158
1.08
0.06
2.4
1.4
—
—
—
0
0
14
130
1.08
0.04
3.4
3.3
4.6
4.4
e9/l
0.12
14
130
172
1740
0.99
0.04
1.4
1.4
—
—
—
0
0
13
140
0.93
0.04
4.3
4.6
—
—
—
0
0
17
160
1.06
0.04
2.9
1.4
—
—
—
0
0
17
160
1.06
0.04
2.9
1.4
—
—
—
0
0
17
160
1.06
0.04
2.9
1.4
—
—
—
0
0
590
5882
1.01
0.04
16.0
14.6
39.0
38.8
%
0.13
438
4140
175
1733
1.01
0.03
6.2
6.6
—
—
—
0
0
13
139
0.93
0.03
3.3
1.8
—
—
—
0
0
55
538
1.02
0.03
6.5
2.8
—
—
—
0
0
184
1825
1.01
0.03
1.6
1.6
1.3
1.3
mmol/l
0.55
164
1530
21
219
0.96
0.03
1.2
1.4
324.6
300.8
ug/g
—
10
126
26
269
0.97
0.02
2.0
1.6
—
—
—
0
0
18
172
1.05
0.02
2.6
2.4
—
—
—
0
0
53
521
1.02
0.02
6.7
2.8
2.3
2.1
mmol/l
0.11
45
421
25
258
0.97
0.02
1.0
1.1
—
—
—
0
0
459
4579
1.01
0.01
3.8
3.6
—
—
—
0
0
156
1551
1.01
0.01
1.6
1.5
23.0
22.2
nmol/l
0.23
122
1300
65
643
1.01
0.01
4.6
6.3
1.7
1.3
mmol/l
0.37
53
517
13
136
0.96
0.00
1.1
1.6
—
—
—
0
0
10
95
1.05
0.00
6.9
1.7
56.1
60.0
%
—
10
95
14
135
1.04
0.00
3.4
3.5
61.4
59.1
%
0.32
14
135
16
164
0.98
0.00
1.1
1.2
—
—
—
0
0
19
193
0.98
0.00
16.7
8.1
—
—
—
0
0
15
148
1.01
0.00
3.2
1.4
—
—
—
0
0
22
222
0.99
0.00
4.8
5.0
1.0
0.9
%
0.90
22
208
328
3284
1.00
0.00
3.8
3.9
0.0
0.0
estimate
0.00
73
601
57
568
1.00
0.00
3.8
4.0
—
—
—
0
0
64
639
1.00
0.00
4.8
6.4
12.2
12.5
kpa
0.20
59
614
152
1521
1.00
0.00
4.2
3.8
—
—
—
0
0
156
1561
1.00
0.00
3.5
3.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
10.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
1.4
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
132
1320
1.00
0.00
3.1
2.7
2.5
2.5
mmol/l
0.06
111
1165
8
84
0.95
0.00
3.6
1.5
—
—
—
0
0
5
59
0.85
0.00
2.6
2.5
—
—
—
0
0
7
69
1.01
0.00
3.4
2.6
—
—
—
0
0
5
56
0.89
0.00
1.0
1.1
—
—
—
0
0
9
94
0.96
0.00
4.6
4.9
360.1
374.1
umol/l
—
9
80
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
0.00
1.0
1.1
—
—
—
0
0
9
94
0.96
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
6
59
1.02
0.00
1.3
1.2
32.4
33.5
g/l
—
6
52
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
6.2
—
0
9
0
8
0.00
0.00
0.0
5.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
16.2
—
0
7
35
350
1.00
0.00
4.3
2.5
121.6
127.0
g/l
0.77
35
342
5
52
0.96
0.00
1.2
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_VAGINA and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_VAGINA 0.981 [0.85, 1.14] 0.799
Birth year 0.997 [0.99, 1.01] 0.46

During the follow-up period (1.1.1998 — 31.12.2019), 326 out of 2726 females with CD2_BENIGN_VAGINA died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_VAGINA.

N-year risk Females Males
1 0.083% No data
5 0.496% No data
10 1.422% No data
15 2.908% No data
20 5.287% No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_VAGINA – Benign neoplasm: Vulva

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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