vulvar carcinoma: A carcinoma that arises from epithelial cells of the mammalian vulva
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleonly females |
293218 |
2. Check conditionsNone |
293218 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
765 |
4. Check minimum number of eventsNone |
765 |
5. Include endpointsNone |
765 |
6. Filter based on genotype QC (FinnGen only) |
743 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D28
- Name in latin
- Neoplasma benignum vulvae
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Vulva
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of other and unspecified female genital organs
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5127 | 5127 | - |
| Only index persons | 4729 | 4729 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.15 | - |
| Only index persons | 0.17 | 0.17 | - |
| Median age at first event (years) | |||
| Whole population | - | 42.27 | - |
| Only index persons | - | 41.49 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 743 | 743 | - |
| Unadjusted period prevalence (%) | 0.26 | 0.26 | - |
| Median age at first event (years) | 41.54 | 41.54 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 765
- Matched controls
- 7650
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
84.8
307.7
201
32
D28.0
ICD-10 Finland
Benign neoplasm: Vulva
5472.7
307.7
524
*
22120
ICD-8 Finland
Benign neoplasm of other female genital organs, Vulva
+∞
141.1
131
*
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
29.7
74.5
50
18
22121, ,
ICD-8 Finland
+∞
57.0
54
*
22122, ,
ICD-8 Finland
+∞
54.9
52
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
6.4
48.1
85
147
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.5
15.0
108
480
N75.0
ICD-10 Finland
Cyst of Bartholin gland
5.9
12.3
22
38
LFW96
NOMESCO Finland
Other operation on vulva or perineum
60.9
10.6
12
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
10.5
123
663
N90.7
ICD-10 Finland
Vulvar cyst
14.5
10.5
17
12
ULA02
NOMESCO Finland
Kolposcopy
2.1
10.5
112
584
R01AD09
ATC
mometasone; nasal
1.6
8.4
383
2990
LFC00
NOMESCO Finland
Partial excision of vulva
13.2
7.9
13
10
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.6
7.6
532
4520
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
7.6
297
2222
62212
ICD-8 Finland
Infective diseases of uterus (except cervix), vagina and vulva, Bartholinitis acuta
13.5
7.4
12
9
A02BC05
ATC
esomeprazole; systemic
1.5
7.2
332
2568
8473
FHL
Guinea pig or gland excision
8.0
7.1
15
19
J02AC01
ATC
fluconazole; systemic
1.5
7.1
382
3048
J01DA01
ATC
[U] cefalexin
1.5
7.0
486
4085
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
7.0
83
449
R03AC02
ATC
salbutamol; inhalant
1.5
6.8
444
3673
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
6.8
279
2102
J01AA02
ATC
doxycycline; systemic
1.6
6.7
611
5423
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.4
6.6
23
69
M79.1
ICD-10 Finland
Myalgia
1.7
6.5
129
815
X01
ICPC
Genital pain female
5.4
6.5
18
34
J01CA04
ATC
amoxicillin; systemic
1.6
6.5
624
5584
UKC02
NOMESCO Finland
Cystoscopy
1.9
6.1
85
484
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
136
856
1.72
7.01
5.0
4.4
32.79
34.02
%
0.66
106
545
489
4213
1.45
5.50
3.4
2.9
48.10
42.07
u/l
0.55
455
3898
562
5088
1.39
3.95
4.4
4.3
12.73
12.55
mm/h
0.12
519
4686
572
5203
1.39
3.84
7.2
7.1
78.62
77.10
u/l
0.34
539
4866
362
3081
1.33
3.74
5.2
5.1
1.23
1.22
mmol/l
0.76
321
2796
713
6818
1.67
3.24
16.0
15.0
3.93
3.93
mmol/l
0.05
696
6611
254
2094
1.32
3.15
2.5
2.3
54.75
59.10
u/l
0.80
236
1908
203
1623
1.34
3.10
2.5
2.0
—
—
—
0
0
159
1229
1.37
3.02
1.7
1.7
1268.34
1210.51
nmol/l
0.24
116
893
387
3389
1.29
3.01
6.6
5.9
1.23
1.22
mmol/l
0.43
325
2884
710
6804
1.61
2.92
15.9
14.8
139.68
139.71
mmol/l
0.12
695
6615
171
1344
1.35
2.91
1.3
1.3
15.06
32.82
iu/ml
4.84
53
457
40
230
1.78
2.89
2.2
2.0
2877.34
2476.77
u/l
0.05
14
93
204
1652
1.32
2.83
1.5
1.4
—
—
—
0
0
328
2832
1.28
2.79
13.7
13.0
1.24
1.18
inr
0.56
82
818
6
10
6.04
2.70
3.7
1.3
96.98
88.80
ng/l
—
6
10
321
2775
1.27
2.67
2.1
2.0
103.29
98.00
pmol/l
0.89
149
1298
87
622
1.45
2.58
2.1
2.1
367.15
372.31
nmol/l
0.08
75
574
394
3510
1.25
2.48
5.0
5.6
10.59
10.32
umol/l
0.15
370
3315
691
6617
1.46
2.47
14.4
13.2
18.29
20.47
mg/l
1.19
561
5171
195
1598
1.30
2.45
2.4
2.4
9409.25
4464.91
umol/l
0.54
172
1383
95
698
1.41
2.44
2.0
2.3
6.95
6.61
umol/l
0.06
85
588
663
6309
1.38
2.41
12.7
12.3
80.30
80.40
ml/min/173m2
0.04
559
5137
15
64
2.37
2.40
7.7
6.1
12.98
12.43
mg/l
0.16
15
57
162
1303
1.31
2.33
1.3
1.3
6.43
10.80
u/ml
0.58
60
477
414
3740
1.23
2.19
3.9
4.2
6.75
6.55
mmol/l
0.93
388
3463
360
3205
1.23
2.18
2.6
2.4
—
—
—
0
0
724
7026
1.57
2.11
11.1
10.3
23.20
23.47
u/l
0.18
697
6763
9
31
2.93
2.07
1.0
1.4
—
—
—
0
0
18
89
2.05
2.07
1.3
1.3
—
—
—
0
0
349
3111
1.22
2.05
2.4
2.3
80.50
79.63
nmol/l
0.23
295
2779
18
90
2.02
2.02
1.3
1.3
—
—
—
0
0
18
90
2.02
2.02
1.3
1.3
—
—
—
0
0
19
98
1.96
1.96
1.4
1.2
0.61
0.63
nmol/l
0.13
19
92
18
92
1.98
1.91
1.3
1.3
—
—
—
0
0
18
92
1.98
1.91
1.3
1.3
—
—
—
0
0
18
92
1.98
1.91
1.3
1.3
—
—
—
0
0
77
572
1.38
1.89
3.1
3.1
109.07
78.59
ng/l
1.31
62
498
235
2025
1.23
1.89
1.8
2.1
118.81
145.84
u/l
1.32
217
1909
357
3215
1.21
1.83
6.8
5.7
27.70
28.77
%
1.19
336
2989
495
4601
1.21
1.81
5.3
4.8
1478.17
2410.35
e6/l
—
6
65
596
5652
1.25
1.77
5.0
4.5
14.54
14.80
pmol/l
1.84
542
5158
352
3182
1.20
1.69
6.5
5.5
58.10
56.76
%
1.49
330
2954
49
343
1.46
1.69
1.4
1.4
—
—
—
0
0
33
212
1.58
1.68
2.5
3.6
24.94
25.10
mmol/l
0.12
27
202
8
32
2.52
1.60
2.5
1.6
719.13
753.03
e6/l
—
8
32
717
6985
1.42
1.58
16.0
15.3
71.37
69.45
umol/l
0.74
717
6985
225
1962
1.21
1.58
3.3
2.9
6.14
6.42
mmol/l
0.49
183
1654
14
72
1.96
1.49
1.6
1.5
—
—
—
0
0
268
2386
1.19
1.49
3.3
3.4
23.07
42.61
ng/l
0.66
159
1592
668
6452
1.28
1.47
5.9
5.4
1.83
2.07
mu/l
0.68
618
5923
212
1854
1.20
1.43
3.4
3.1
411.32
421.85
mg/l
0.01
117
1043
636
6118
1.23
1.39
5.8
5.5
40.00
39.27
mmol/mol
1.17
583
5636
206
1803
1.20
1.38
2.4
2.8
1123.24
980.49
ng/l
0.19
166
1506
742
7293
1.58
1.36
21.8
19.9
39.54
39.28
%
0.68
703
6820
649
6261
1.24
1.35
4.1
3.9
1.28
1.24
mmol/l
0.61
592
5682
742
7297
1.56
1.30
22.0
20.0
263.83
261.95
e9/l
0.34
725
7117
8
34
2.37
1.29
1.0
1.1
—
—
—
0
0
19
114
1.68
1.29
1.3
1.2
—
—
—
0
0
187
1632
1.19
1.29
2.3
2.2
2.91
3.05
mg/l
0.26
163
1372
17
99
1.73
1.28
1.4
1.9
—
—
—
0
0
220
1949
1.18
1.28
3.8
3.6
15.92
6.86
mg/mmol
1.03
126
1088
742
7299
1.55
1.27
22.0
20.0
4.40
4.39
e12/l
0.17
725
7098
8
35
2.30
1.27
2.3
1.5
—
—
—
0
0
742
7300
1.55
1.26
22.1
20.1
131.66
131.69
g/l
0.02
736
7191
14
77
1.83
1.26
1.9
1.4
368.37
365.81
pmol/l
0.01
14
70
239
2138
1.17
1.23
2.8
2.9
26.36
29.32
u/l
1.76
225
2034
39
531
0.72
1.20
2.6
2.5
46.58
67.89
ml/min/173m2
2.37
12
220
6
26
2.32
1.19
1.5
1.1
—
—
—
0
0
6
26
2.32
1.19
1.5
1.1
—
—
—
0
0
186
1639
1.18
1.15
1.3
1.3
0.51
2.03
u/ml
2.83
50
401
7
30
2.35
1.12
1.7
2.1
33.89
50.53
ug/l
—
7
30
16
96
1.68
1.11
1.5
1.5
—
—
—
0
0
59
463
1.30
1.08
1.4
1.6
—
—
—
0
0
310
2851
1.15
1.08
4.9
4.1
35.62
35.80
g/l
0.24
285
2640
670
6517
1.23
1.08
4.6
4.4
1.57
1.60
mmol/l
0.64
615
5978
328
3029
1.15
1.08
3.1
2.8
80.46
89.53
ug/l
0.86
300
2782
44
332
1.35
1.06
2.9
3.3
1.26
2.14
mmol/l
0.74
34
262
437
4118
1.14
1.05
3.2
3.0
—
—
—
0
0
22
146
1.52
1.04
1.6
1.7
4759.33
16582.01
e6/l
1.48
12
104
416
3911
1.14
1.03
8.1
8.8
4.19
3.95
e9/l
1.14
364
3425
11
60
1.85
1.03
1.4
1.2
—
—
—
0
0
10
53
1.90
1.01
2.2
1.4
—
—
—
0
0
92
769
1.22
1.01
6.4
4.2
1.07
1.04
mmol/l
0.42
83
700
51
397
1.30
1.01
1.4
1.7
—
—
—
0
0
16
99
1.63
1.00
1.4
1.3
—
—
—
0
0
673
6559
1.22
1.00
4.6
4.4
4.76
4.85
mmol/l
1.61
620
6051
14
85
1.66
0.94
1.6
1.4
—
—
—
0
0
22
152
1.46
0.89
1.4
1.4
—
—
—
0
0
12
72
1.68
0.85
1.6
1.4
—
—
—
0
0
11
179
0.61
0.85
2.1
1.8
—
—
—
0
0
683
6684
1.20
0.85
5.1
5.0
2.77
2.83
mmol/l
1.04
631
6141
6
31
1.94
0.84
1.5
1.1
—
—
—
0
0
6
31
1.94
0.84
1.5
1.1
—
—
—
0
0
18
261
0.68
0.84
2.3
2.2
—
—
—
0
0
39
302
1.31
0.83
1.4
1.6
—
—
—
0
0
47
374
1.27
0.82
1.0
1.1
—
—
—
0
0
30
224
1.35
0.81
1.7
1.7
—
—
—
0
0
8
47
1.71
0.81
1.4
1.3
1.07
1.63
nmol/l
—
8
41
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
8
48
1.67
0.79
2.5
1.3
—
—
—
0
0
8
48
1.67
0.79
2.5
1.3
—
—
—
0
0
8
48
1.67
0.79
2.5
1.3
—
—
—
0
0
32
244
1.33
0.76
1.9
1.8
—
—
—
0
0
16
107
1.51
0.76
1.0
1.0
—
14.13
—
0
9
0
28
0.00
0.76
0.0
1.2
—
—
—
0
0
158
1423
1.14
0.74
1.6
1.7
63846610.98
15013391.21
pmol/l
0.35
130
1159
29
219
1.34
0.74
1.8
1.9
6.89
2.37
ug/l
0.50
24
194
9
55
1.64
0.73
1.0
1.0
—
—
—
0
0
15
100
1.51
0.73
1.3
1.1
6.16
2.20
u/ml
—
8
50
71
601
1.20
0.73
2.3
2.0
0.22
0.21
g/l
0.35
65
577
132
1475
0.87
0.72
4.1
4.3
1.01
1.02
kg/l
0.38
17
222
665
6512
1.16
0.71
4.7
4.5
5.88
5.83
mmol/l
0.49
608
5901
5
26
1.93
0.70
1.2
1.0
—
—
—
0
0
7
41
1.71
0.70
2.0
1.4
75.57
76.66
umol/l
—
7
41
9
58
1.56
0.70
2.2
1.5
—
—
—
0
0
9
58
1.56
0.70
2.2
1.5
—
—
—
0
0
9
58
1.56
0.70
2.0
2.0
—
—
—
0
0
109
961
1.16
0.70
2.8
2.2
12.75
12.76
umol/l
0.00
104
892
10
61
1.65
0.68
1.3
1.1
—
—
—
0
0
10
61
1.65
0.68
1.3
1.1
—
—
—
0
0
170
1552
1.12
0.65
1.7
1.7
0.95
0.98
mg/l
0.11
125
1167
10
62
1.62
0.65
2.2
1.3
—
—
—
0
0
10
62
1.62
0.65
1.3
1.1
—
—
—
0
0
10
62
1.62
0.65
1.3
1.1
—
—
—
0
0
10
62
1.62
0.65
1.3
1.1
—
—
—
0
0
5
30
1.67
0.61
1.8
3.6
862.00
662.77
u/ml
—
5
30
99
877
1.15
0.61
2.7
2.2
2.38
2.40
g/l
0.17
93
811
114
1021
1.14
0.60
3.3
2.8
0.82
0.81
mmol/l
0.34
95
956
12
80
1.51
0.60
2.7
1.7
38.50
53.53
u/ml
0.10
12
80
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
15
106
1.42
0.58
2.3
1.5
—
—
—
0
0
23
176
1.32
0.57
1.3
1.3
—
—
—
0
0
6
36
1.67
0.56
1.0
1.1
7.83
25.91
u/l
—
6
31
176
1625
1.11
0.56
3.7
3.4
96.47
95.14
%
0.29
169
1576
6
37
1.63
0.55
2.5
1.3
1.38
1.67
g/l
—
6
37
22
169
1.31
0.53
1.4
1.3
—
—
—
0
0
49
575
0.84
0.53
3.1
3.5
1.22
1.24
mmol/l
0.56
42
492
13
91
1.44
0.53
2.1
1.4
—
—
—
0
0
13
91
1.44
0.53
2.1
1.4
—
—
—
0
0
6
39
1.54
0.53
1.8
1.5
5.50
7.98
u/l
—
6
33
6
40
1.50
0.51
1.0
1.1
—
—
—
0
0
259
2450
1.09
0.49
3.3
3.3
2.37
2.37
mmol/l
0.10
212
2150
11
155
0.71
0.48
1.0
1.2
3.79
3.84
mmol/l
0.07
11
145
91
817
1.13
0.48
2.5
2.3
21.01
21.51
%
0.14
73
690
18
137
1.32
0.47
2.2
1.5
—
—
—
0
0
135
1242
1.11
0.47
1.6
1.5
—
—
—
0
0
10
142
0.70
0.46
1.3
1.6
—
—
—
0
0
30
246
1.23
0.46
1.2
1.8
—
—
—
0
0
22
174
1.27
0.45
1.0
1.1
—
—
—
0
0
71
631
1.14
0.44
1.9
1.5
1.48
1.34
%
1.31
59
552
11
78
1.42
0.43
1.1
1.2
—
—
—
0
0
77
690
1.13
0.43
3.7
3.8
2.98
10.33
ug/l
3.56
65
555
5
31
1.62
0.43
1.4
1.4
14.88
14.51
pmol/l
—
5
24
5
32
1.57
0.42
1.0
1.0
—
—
—
0
0
5
33
1.52
0.41
1.2
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.9
—
6.07
—
0
10
18
142
1.27
0.39
2.2
1.5
—
—
—
0
0
41
356
1.16
0.37
1.5
1.6
—
—
—
0
0
13
99
1.32
0.35
1.2
1.1
—
—
—
0
0
6
42
1.43
0.35
1.2
1.1
—
—
—
0
0
6
42
1.43
0.35
2.7
1.7
—
—
—
0
0
71
643
1.11
0.35
3.4
4.2
244.63
249.14
u/l
0.10
63
606
74
672
1.11
0.35
2.1
2.0
—
—
—
0
0
246
2567
0.94
0.34
4.1
4.1
—
—
—
0
0
21
253
0.83
0.33
1.3
1.7
—
—
—
0
0
62
563
1.11
0.30
1.2
1.2
174.24
164.47
iu/ml
0.07
22
232
63
690
0.91
0.29
2.0
1.7
—
—
—
0
0
17
206
0.82
0.29
1.5
1.3
157.36
231.52
miu/ml
—
10
98
8
107
0.75
0.29
1.3
1.4
—
—
—
0
0
21
176
1.20
0.29
1.3
1.5
—
—
—
0
0
128
1206
1.07
0.29
3.7
3.6
242.13
364.74
ng/l
0.25
86
893
14
112
1.25
0.28
1.4
1.5
—
—
—
0
0
68
625
1.10
0.27
2.1
2.1
33.87
36.12
u/l
0.17
55
521
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
20
168
1.20
0.27
2.3
2.6
0.41
0.39
u/ml
0.07
12
104
66
606
1.10
0.27
2.1
1.8
—
—
—
0
0
197
1889
1.06
0.26
2.9
3.1
90.06
54.40
e6/l
0.26
146
1420
5
72
0.69
0.26
2.4
1.1
—
—
—
0
0
182
1742
1.06
0.26
2.8
3.0
0.30
0.43
e6/l
0.59
134
1299
9
77
1.17
0.24
1.0
1.0
—
—
—
0
0
5
39
1.28
0.23
1.6
1.4
—
—
—
0
0
5
39
1.28
0.23
1.6
1.4
—
—
—
0
0
5
39
1.28
0.23
1.0
1.0
526.20
353.08
ng/l
—
5
25
5
40
1.25
0.22
1.0
1.0
795.00
690.96
ng/l
—
5
26
5
40
1.25
0.22
1.0
1.0
76.80
55.15
ng/l
—
5
26
5
41
1.22
0.22
1.6
1.2
—
—
—
0
0
17
199
0.85
0.22
2.1
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
349
3412
1.04
0.21
3.8
3.9
0.00
0.01
estimate
0.80
74
604
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
103.00
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
17
145
1.18
0.20
2.7
2.0
130.00
128.15
g/l
—
10
108
0
14
0.00
0.20
0.0
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
90
851
1.07
0.20
7.3
6.3
—
—
—
0
0
10
122
0.82
0.19
1.9
1.6
—
—
—
0
0
33
362
0.91
0.18
1.6
1.5
—
—
—
0
0
14
119
1.18
0.17
4.4
2.3
16.68
15.96
%
—
6
63
345
3385
1.03
0.17
5.1
5.3
0.00
0.00
estimate
0.50
74
613
5
67
0.74
0.17
1.0
1.1
—
—
—
0
0
50
535
0.93
0.16
4.6
7.0
115.92
118.48
g/l
0.38
50
521
16
139
1.15
0.16
3.2
3.7
25.69
18.59
mg/l
—
9
84
8
71
1.13
0.16
1.1
1.1
—
36.33
—
0
6
8
71
1.13
0.16
1.1
1.1
—
55.22
—
0
9
48
514
0.93
0.16
2.8
2.8
65.33
67.09
g/l
0.63
42
467
8
73
1.10
0.15
3.0
2.6
12.82
13.26
%
—
8
73
25
226
1.11
0.15
4.4
4.9
2.02
1.55
%
0.79
25
211
46
492
0.93
0.15
5.7
3.0
4.36
4.47
pmol/l
0.43
41
430
17
150
1.14
0.14
1.4
1.5
—
—
—
0
0
46
490
0.93
0.14
2.0
2.2
4.39
6.17
ug/l
0.87
37
421
66
694
0.95
0.14
2.0
1.7
—
—
—
0
0
14
122
1.15
0.14
6.4
7.1
104.14
105.43
mmol/l
0.46
14
109
184
1793
1.03
0.13
3.9
4.2
0.00
0.00
estimate
1.08
73
608
22
199
1.11
0.13
1.5
1.5
0.57
0.09
iu/ml
—
5
30
20
221
0.90
0.13
1.2
1.4
340.22
302.85
ug/g
—
9
128
21
190
1.11
0.13
1.1
1.2
—
—
—
0
0
15
168
0.89
0.11
1.0
1.3
439.07
485.65
mg/l
0.40
15
158
10
86
1.16
0.11
2.6
1.5
—
—
—
0
0
100
969
1.04
0.10
2.4
2.7
4.37
4.35
e6/l
0.00
56
482
52
545
0.95
0.10
1.5
1.6
—
—
—
0
0
17
154
1.11
0.10
2.2
2.4
—
—
—
0
0
5
44
1.14
0.10
1.6
1.3
—
—
—
0
0
5
47
1.06
0.09
1.0
1.3
—
—
—
0
0
23
213
1.08
0.09
2.7
1.8
8.99
4.68
iu/l
—
7
70
5
48
1.04
0.09
1.8
1.4
1.19
1.00
g/l
—
5
48
5
48
1.04
0.09
1.2
1.2
—
—
—
0
0
6
58
1.03
0.08
1.0
1.3
—
—
—
0
0
5
64
0.78
0.08
1.0
1.1
—
—
—
0
0
7
64
1.09
0.08
3.0
3.5
—
—
—
0
0
6
70
0.86
0.07
1.0
1.1
—
—
—
0
0
51
491
1.04
0.07
2.2
2.4
57.80
25.46
au/ml
—
6
32
23
244
0.94
0.06
1.0
1.1
—
—
—
0
0
159
1567
1.02
0.05
1.6
1.5
22.92
22.12
nmol/l
0.25
125
1314
34
326
1.04
0.05
1.4
1.4
—
—
—
0
0
18
169
1.07
0.05
1.3
1.4
—
—
—
0
0
103
1046
0.98
0.04
2.4
2.6
1.64
1.29
e6/l
0.30
61
560
11
101
1.09
0.04
1.1
1.2
—
—
—
0
0
38
392
0.97
0.04
1.4
1.3
—
—
—
0
0
12
129
0.93
0.03
1.6
1.4
—
—
—
0
0
12
129
0.93
0.03
1.6
1.4
—
—
—
0
0
100
986
1.02
0.03
2.1
1.8
—
—
—
0
0
18
189
0.95
0.03
1.5
1.4
—
—
—
0
0
577
5784
0.99
0.02
17.0
16.0
15.85
14.90
%
2.47
567
5677
132
1332
0.99
0.02
3.1
2.7
2.46
2.46
mmol/l
0.06
111
1176
18
188
0.96
0.02
1.5
1.4
—
—
—
0
0
10
93
1.08
0.02
1.2
1.1
—
—
—
0
0
11
103
1.07
0.02
1.4
1.1
2.80
2.74
u/ml
—
5
42
64
649
0.98
0.02
4.8
6.5
12.16
12.51
kpa
0.19
59
623
135
1340
1.01
0.01
2.5
2.5
5.28
8.08
e6/l
2.46
117
1208
18
187
0.96
0.01
1.5
1.4
—
—
—
0
0
18
187
0.96
0.01
1.5
1.4
—
—
—
0
0
14
134
1.05
0.00
3.4
3.2
4.60
4.37
e9/l
0.12
14
134
19
196
0.97
0.00
1.5
1.5
—
—
—
0
0
22
214
1.03
0.00
1.3
1.2
—
—
—
0
0
28
286
0.98
0.00
2.5
2.1
37.38
39.55
u/l
0.22
21
250
11
105
1.05
0.00
2.0
1.3
—
—
—
0
0
35
355
0.99
0.00
6.0
6.9
25.51
24.91
mmol/l
0.49
35
338
22
217
1.01
0.00
1.5
1.4
—
—
—
0
0
13
128
1.02
0.00
2.2
1.6
—
—
—
0
0
35
353
0.99
0.00
4.3
2.5
121.57
127.02
g/l
0.79
35
345
184
1845
1.00
0.00
1.6
1.6
1.28
1.33
mmol/l
0.56
164
1545
53
527
1.01
0.00
6.7
2.8
2.27
2.09
mmol/l
0.15
46
441
65
653
0.99
0.00
4.6
6.4
1.66
1.32
mmol/l
0.38
54
527
32
318
1.01
0.00
1.4
1.5
—
—
—
0
0
14
139
1.01
0.00
3.4
3.5
61.43
59.02
%
0.33
14
139
67
672
1.00
0.00
3.5
3.2
—
—
—
0
0
21
209
1.00
0.00
1.5
1.6
—
155.56
—
0
9
336
3357
1.00
0.00
3.8
3.9
0.00
0.00
estimate
0.50
78
652
24
241
1.00
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
585.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
54
0.93
-0.00
2.4
1.6
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
2.60
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
2.1
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
97
0.93
-0.00
4.6
5.3
360.11
374.96
umol/l
—
9
83
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
59.90
—
0
5
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_VAGINA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_VAGINA | 0.981 [0.85, 1.14] | 0.799 |
| Birth year | 0.997 [0.99, 1.01] | 0.46 |
During the follow-up period (1.1.1998 — 31.12.2019), 326 out of 2726 females with CD2_BENIGN_VAGINA died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_VAGINA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.083% | No data |
| 5 | 0.496% | No data |
| 10 | 1.422% | No data |
| 15 | 2.908% | No data |
| 20 | 5.287% | No data |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_VAGINA – Benign neoplasm: Vulva
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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