Benign neoplasm: Uterine tubes and ligaments

CD2_BENIGN_UTERINE_TUBES_LIGAMENTS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D28.7&
  • Hospital discharge: ICD-9 2210
  • Hospital discharge: ICD-8 2210
  • Cause of death: ICD-10 D28.7&
  • Cause of death: ICD-9 2210
  • Cause of death: ICD-8 2210

2 out of 7 registries used, show all original rules.

223

4. Check minimum number of events

None

223

5. Include endpoints

None

223

6. Filter based on genotype QC (FinnGen only)

220

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D28
Name in latin
Neoplasma benignum alterius organi genitalis feminini specificati

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1728 1728 -
Only index persons 1555 1555 -
Unadjusted period prevalence (%)
Whole population 0.05 0.05 -
Only index persons 0.06 0.06 -
Median age at first event (years)
Whole population - 39.39 -
Only index persons - 37.97 -

-FinnGen-

Key figures

All Female Male
Number of individuals 220 220 -
Unadjusted period prevalence (%) 0.08 0.08 -
Median age at first event (years) 36.36 36.36 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
223
Matched controls
2230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
22101
ICD-8 Finland
Benign neoplasm of other female genital organs, Fallopian tube and broad ligament
+∞
127.7
110
*
2210A
ICD-9 Finland
Benign neoplasm of other female genital organs, Fallopian tube and uterine ligaments
+∞
71.8
65
*
D28.7
ICD-10 Finland
Benign neoplasm: Other specified female genital organs
+∞
43.1
40
*
8204
FHL
Salpingo-oophorectomy
10.8
9.7
18
18
8201
FHL
Ovarian preservation exploration and related procedures, eg resection, enucleation or ovariolysis
6.6
6.3
15
24

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
38
183
2.30
4.71
2.6
3.7
—
—
—
0
0
84
607
1.62
2.91
3.8
3.7
—
—
—
0
0
15
63
2.48
2.52
3.5
3.4
—
—
—
0
0
106
856
1.45
2.03
2.1
2.1
—
—
—
0
0
124
1435
0.69
1.92
3.9
3.9
—
—
—
0
0
50
684
0.65
1.89
3.3
3.6
7.41
7.40
ph
—
10
128
40
539
0.69
1.35
3.9
3.0
—
—
—
0
0
0
39
0.00
1.35
0.0
2.0
—
—
—
0
0
42
556
0.70
1.28
3.7
3.1
0.18
0.51
e6/l
1.93
35
412
213
2048
1.89
1.16
11.1
10.7
24.62
23.33
u/l
0.60
204
1964
5
21
2.41
1.09
1.4
2.8
—
—
—
0
0
194
1831
1.46
1.09
6.2
5.8
39.47
39.85
mmol/mol
0.30
179
1691
163
1498
1.33
1.08
4.6
4.3
11.97
13.45
mm/h
0.99
149
1364
72
598
1.30
1.02
2.0
2.3
—
—
—
0
0
202
1927
1.51
1.00
5.1
4.6
4.80
4.83
mmol/l
0.16
187
1771
16
100
1.65
1.00
1.3
1.3
—
—
—
0
0
88
753
1.28
0.99
3.9
3.8
27.00
27.24
ng/l
0.01
62
553
5
23
2.20
0.98
1.0
1.5
1218.20
164.16
u/ml
—
5
23
7
36
1.97
0.98
2.4
2.3
7.67
7.68
kpa
—
7
36
6
28
2.17
0.92
1.3
1.7
—
—
—
0
0
205
1970
1.50
0.87
5.6
5.3
2.83
2.80
mmol/l
0.24
187
1802
49
591
0.78
0.78
3.3
3.2
16.42
53.32
e6/l
1.91
42
447
23
309
0.71
0.77
3.6
2.9
6.93
4.93
e6/l
0.23
15
158
5
26
1.94
0.71
2.6
2.9
—
—
—
0
0
31
392
0.76
0.71
3.5
4.1
119.52
96.71
ng/l
0.12
23
312
32
251
1.32
0.69
1.2
1.2
—
—
—
0
0
5
27
1.87
0.69
1.6
2.0
—
—
—
0
0
100
898
1.21
0.68
6.5
5.8
—
—
—
0
0
148
1380
1.22
0.67
5.1
4.7
—
—
—
0
0
12
78
1.57
0.67
2.8
4.2
—
—
—
0
0
62
715
0.82
0.66
4.1
3.8
404.41
90.19
e6/l
0.40
44
492
106
963
1.19
0.62
4.0
5.0
1.22
1.22
mmol/l
0.51
90
877
59
508
1.22
0.61
1.5
1.5
24.41
23.20
nmol/l
0.19
43
423
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
16
116
1.41
0.56
3.1
2.4
—
—
—
0
0
73
648
1.19
0.55
2.5
2.2
84.26
55.05
u/l
0.67
68
592
206
2005
1.36
0.54
15.6
16.4
140.05
139.79
mmol/l
0.80
200
1946
121
1122
1.17
0.53
4.2
4.4
6.60
6.64
mmol/l
0.11
111
1038
214
2097
1.51
0.53
22.1
21.1
4.42
4.38
e12/l
0.80
205
2034
214
2097
1.51
0.53
21.9
21.0
29.94
30.17
pg
1.21
207
2061
214
2097
1.51
0.53
22.2
21.2
131.93
131.35
g/l
0.31
209
2061
214
2096
1.52
0.53
21.8
21.1
39.94
39.36
%
1.55
200
1949
214
2096
1.52
0.53
21.9
21.0
90.74
91.29
fl
1.11
207
2060
16
118
1.38
0.52
1.2
1.3
—
47.79
—
0
7
189
1823
1.24
0.51
4.7
4.1
1.27
1.25
mmol/l
0.21
171
1650
55
479
1.20
0.51
2.7
2.2
3.03
3.30
mg/l
0.43
49
411
52
452
1.20
0.49
4.7
4.7
1.01
1.02
kg/l
0.47
11
60
33
274
1.24
0.48
1.4
1.3
146.67
636.67
titre
—
6
72
206
2010
1.33
0.47
15.7
16.5
3.94
3.95
mmol/l
0.12
201
1946
25
201
1.27
0.47
1.8
1.5
—
—
—
0
0
13
94
1.41
0.47
2.2
1.9
—
—
—
0
0
109
1011
1.15
0.46
3.9
4.3
0.00
0.00
estimate
-0.00
14
201
197
1914
1.25
0.45
5.3
4.5
1.55
1.62
mmol/l
1.69
181
1752
197
1915
1.25
0.44
14.8
14.1
16.51
20.71
mg/l
1.60
156
1487
42
483
0.84
0.43
1.3
1.3
—
—
—
0
0
194
1989
0.81
0.43
13.7
13.1
—
—
—
0
0
198
1928
1.24
0.42
5.4
4.8
5.78
5.91
mmol/l
0.98
182
1748
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
2.9
—
597.09
—
0
11
0
16
0.00
0.41
0.0
2.4
—
461.45
—
0
11
8
60
1.35
0.40
1.4
1.7
87.12
187.14
ug/l
—
8
54
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
109
1019
1.14
0.40
4.9
5.6
0.00
0.00
estimate
-0.00
12
184
8
112
0.70
0.38
20.8
3.0
5.83
4.51
pmol/l
—
8
93
53
591
0.86
0.38
1.7
1.6
1.22
1.31
mmol/l
0.49
44
491
102
1088
0.88
0.37
4.8
5.5
9.37
9.93
umol/l
0.41
95
1018
5
37
1.36
0.37
1.0
1.1
—
—
—
0
0
109
1024
1.13
0.36
3.9
4.2
0.00
0.00
estimate
-0.00
14
182
213
2096
1.36
0.36
22.2
21.1
257.61
258.48
e9/l
0.08
205
2041
213
2096
1.36
0.36
22.2
21.1
6.45
6.55
e9/l
0.35
203
2032
16
127
1.28
0.34
2.8
2.5
3.16
4.21
e9/l
2.35
16
102
57
627
0.88
0.33
3.4
3.2
—
—
—
0
0
71
769
0.89
0.33
2.6
3.0
2.36
2.37
mmol/l
0.05
56
672
27
230
1.20
0.33
3.7
3.9
6.08
8.23
ug/l
0.25
22
190
34
387
0.86
0.32
2.0
3.0
480.50
497.12
mosm/kgh2o
0.18
28
332
70
645
1.12
0.31
3.0
2.0
106.78
140.74
u/l
1.34
65
602
17
139
1.24
0.30
1.1
1.2
80.68
161.45
iu/ml
—
5
64
17
205
0.82
0.29
1.4
1.5
—
—
—
0
0
97
914
1.11
0.29
7.4
5.6
30.56
28.36
%
1.36
90
851
7
57
1.24
0.29
4.6
3.3
—
—
—
0
0
7
57
1.24
0.29
1.0
1.1
—
—
—
0
0
8
62
1.30
0.28
4.0
2.1
—
—
—
0
0
190
1858
1.15
0.28
6.5
5.4
14.79
1.90
mu/l
0.49
173
1693
19
159
1.21
0.28
1.3
1.5
—
—
—
0
0
17
141
1.22
0.27
3.6
2.7
—
—
—
0
0
10
77
1.31
0.26
1.1
1.3
—
1.51
—
0
7
87
819
1.10
0.26
3.2
2.8
100.48
92.56
ug/l
0.27
80
742
18
151
1.21
0.26
3.8
4.2
0.13
0.17
%
—
8
47
9
76
1.19
0.25
1.6
1.8
—
—
—
0
0
6
83
0.72
0.24
1.2
1.5
—
—
—
0
0
39
429
0.89
0.23
2.3
2.7
2.45
2.46
mmol/l
0.15
33
374
18
210
0.84
0.23
2.1
2.2
4.11
7.37
umol/l
2.07
18
184
10
79
1.28
0.22
1.6
1.3
—
—
—
0
0
14
167
0.83
0.22
2.9
4.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
146.36
—
0
11
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
1.63
—
0
10
0
10
0.00
0.21
0.0
4.3
—
43.75
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
101
966
1.08
0.21
7.2
5.2
0.04
0.04
e9/l
0.32
89
837
0
13
0.00
0.21
0.0
1.6
—
67.15
—
0
13
0
13
0.00
0.21
0.0
2.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
1.08
—
0
13
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
142.97
—
0
13
91
867
1.08
0.21
7.5
5.5
0.82
0.73
%
0.99
83
796
48
444
1.10
0.20
1.8
1.7
378.98
21098749.77
pmol/l
0.50
40
346
9
115
0.77
0.20
3.3
3.7
—
—
—
0
0
104
997
1.08
0.20
7.3
5.5
0.20
0.18
e9/l
0.81
91
878
0
14
0.00
0.20
0.0
1.1
—
1.98
—
0
14
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
50
1.21
0.20
1.2
1.2
386.33
474.07
mg/l
—
6
45
103
988
1.08
0.19
7.3
5.2
2.15
1.97
e9/l
0.30
91
878
12
143
0.83
0.19
1.2
1.1
—
—
—
0
0
7
58
1.21
0.18
2.1
2.5
—
—
—
0
0
100
961
1.07
0.18
7.3
5.2
0.54
0.56
e9/l
0.43
87
835
7
62
1.13
0.17
6.9
9.1
—
—
—
0
0
57
604
0.92
0.17
3.1
2.9
6.24
6.39
mmol/l
0.14
52
497
58
547
1.08
0.17
4.2
4.7
0.07
0.00
estimate
0.47
14
192
44
410
1.09
0.16
1.6
1.7
1257.13
1273.20
nmol/l
0.03
32
301
94
904
1.07
0.16
7.7
5.7
8.31
8.36
%
0.08
87
839
6
77
0.77
0.16
1.7
1.5
—
—
—
0
0
6
79
0.75
0.16
1.5
1.2
—
—
—
0
0
94
905
1.07
0.15
7.6
5.3
55.77
56.88
%
0.49
87
844
12
102
1.19
0.15
3.8
5.4
27.03
25.40
mmol/l
0.40
12
102
42
449
0.92
0.15
1.5
1.7
1.04
1.05
mg/l
0.02
27
355
52
491
1.08
0.14
4.6
4.1
—
—
—
0
0
23
253
0.90
0.14
1.5
1.3
—
—
—
0
0
16
141
1.15
0.14
3.4
4.1
0.29
0.82
%
—
7
44
89
858
1.06
0.14
2.0
2.0
105.91
100.69
pmol/l
0.33
40
369
205
2029
1.13
0.14
17.2
16.9
70.94
70.79
umol/l
0.04
205
2029
37
396
0.92
0.14
1.3
1.3
39.93
38.08
iu/ml
0.04
12
148
43
457
0.93
0.13
1.4
1.3
0.48
2.34
u/ml
—
8
126
9
109
0.82
0.13
1.6
1.3
—
—
—
0
0
17
152
1.13
0.12
1.1
1.3
—
—
—
0
0
18
162
1.12
0.12
3.8
4.1
0.88
0.92
%
—
8
58
15
168
0.89
0.12
1.5
1.3
—
—
—
0
0
50
525
0.94
0.11
7.7
6.8
—
—
—
0
0
23
249
0.91
0.11
1.5
1.2
—
—
—
0
0
19
173
1.11
0.11
1.2
3.2
16.68
58.20
u/ml
1.11
19
167
17
154
1.11
0.10
3.0
6.3
—
—
—
0
0
18
197
0.91
0.10
1.5
1.4
—
—
—
0
0
5
44
1.14
0.10
1.2
2.0
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
3.38
4.08
mmol/l
—
5
38
5
46
1.09
0.09
1.0
2.1
—
—
—
0
0
77
747
1.05
0.09
3.9
3.2
—
—
—
0
0
6
57
1.05
0.08
1.0
1.2
—
—
—
0
0
16
146
1.10
0.08
4.1
4.2
0.17
0.18
%
—
6
39
85
870
0.96
0.07
8.9
9.2
0.00
0.00
e9/l
1.06
71
717
92
900
1.04
0.07
7.6
5.4
2.85
2.74
%
0.22
85
834
52
538
0.96
0.07
2.8
3.8
—
—
—
0
0
29
305
0.94
0.07
1.5
1.2
—
—
—
0
0
48
496
0.96
0.06
2.0
2.5
331.54
9351.77
umol/l
3.44
39
423
19
202
0.94
0.05
1.4
1.4
—
—
—
0
0
38
394
0.96
0.05
1.9
1.5
2.51
2.46
g/l
0.05
24
227
107
1054
1.03
0.05
4.3
5.7
1.22
1.23
mmol/l
0.60
90
902
116
1146
1.03
0.04
8.8
8.5
3.93
3.95
e9/l
0.04
100
1013
20
190
1.06
0.04
1.3
1.7
—
—
—
0
0
15
142
1.06
0.02
1.3
2.6
—
—
—
0
0
61
620
0.98
0.02
3.5
3.6
2.20
5.76
mg/mmol
1.46
31
347
93
920
1.02
0.02
12.3
12.0
1.27
1.19
inr
0.31
24
273
118
1189
0.98
0.02
3.0
2.9
63.00
47.99
u/l
0.45
108
1097
41
418
0.98
0.01
2.5
2.5
5.50
6.16
e6/l
0.15
36
379
58
588
0.98
0.01
3.0
3.1
14.34
254.22
mg/l
0.87
33
342
26
267
0.97
0.01
1.8
2.0
—
—
—
0
0
154
1547
0.99
0.01
7.1
7.0
76.40
79.79
u/l
0.45
142
1436
13
124
1.05
0.00
4.5
4.7
—
—
—
0
0
12
126
0.95
0.00
1.2
1.3
—
—
—
0
0
19
191
0.99
0.00
1.6
2.8
—
—
—
0
0
38
384
0.99
0.00
1.3
1.3
17.18
12.36
u/ml
0.11
19
141
162
1618
1.00
0.00
5.7
4.5
14.79
14.94
pmol/l
0.31
145
1465
11
107
1.03
0.00
1.5
2.0
1.14
1.08
%
0.16
11
107
12
123
0.97
0.00
1.1
1.3
—
—
—
0
0
23
233
0.99
0.00
2.1
1.9
173.29
128.56
ug/g
0.37
17
184
18
177
1.02
0.00
4.6
3.4
—
—
—
0
0
16
156
1.03
0.00
1.7
1.5
—
—
—
0
0
11
105
1.05
0.00
1.2
1.3
—
—
—
0
0
22
218
1.01
0.00
4.7
6.4
2.39
1.66
mmol/l
0.21
16
181
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
226.12
—
0
5
0
5
0.00
0.00
0.0
1.0
—
4.86
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
3.74
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
125.80
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
8.4
—
0.66
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
30.9
—
92.86
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
52
0.96
-0.00
1.0
5.5
—
—
—
0
0
5
58
0.86
-0.00
2.0
5.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
30.22
—
0
9
49
490
1.00
-0.00
3.9
3.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_UTERINE_TUBES_LIGAMENTS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_UTERINE_TUBES_LIGAMENTS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: CD2_BENIGN_UTERINE_TUBES_LIGAMENTS – Benign neoplasm: Uterine tubes and ligaments

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data