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Malignant neoplasm of heart, mediastinum and pleura, including Hilmo

C3_HEART_MEDIASTINUM_PLEURA_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C38
  • Hospital discharge: ICD-9 16[3-4]
  • Hospital discharge: ICD-8 163[0-1]
  • Cause of death: ICD-10 C38
  • Cause of death: ICD-9 16[3-4]
  • Cause of death: ICD-8 163[0-1]
  • Cause of death: excluded ICD-9 1640
  • Cancer registry: Topography ICD-O-3 C38
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

698

4. Check minimum number of events

None

698

5. Include endpoints

None

698

6. Filter based on genotype QC (FinnGen only)

680

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 680 185 495
Unadjusted period prevalence (%) 0.18 0.07 0.23
Median age at first event (years) 68.89 61.16 71.78

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
698
Matched controls
6980
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
307.7
339
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
48.0
307.7
285
99
H02AB02
ATC
dexamethasone; systemic
159.3
307.7
290
31
C45.0
ICD-10 Finland
Mesothelioma of pleura
+∞
307.7
297
*
A03FA01
ATC
metoclopramide; systemic, rectal
19.6
307.7
365
370
A04AA01
ATC
ondansetron; systemic, rectal
61.9
307.7
200
45
Z51.5
ICD-10 Finland
Palliative care
23.3
243.3
192
112
N02AA05
ATC
oxycodone; systemic
11.3
230.8
351
574
JN4BD
NOMESCO Finland
Extensive body CT
17.2
200.8
184
142
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
21.4
192.3
154
91
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
35.7
184.2
119
40
J94.8
ICD-10 Finland
Other specified pleural conditions
28.5
167.9
117
49
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
9.7
158.0
227
332
9050/3-C38.4
ICD-O-3
Mesothelioma, malignant of pleura, NOS
+∞
152.9
141
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
26.1
149.3
107
48
TGA30
NOMESCO Finland
Thoracocentesis
69.4
145.9
80
13
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
33.8
144.2
94
32
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
1503.3
131.7
124
*
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
35.6
128.3
82
26
UGC12
NOMESCO Finland
Flexible bronchoscopy
9.1
124.1
176
249
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
20.9
118.7
93
51
9052/3-C38.4
ICD-O-3
Epithelioid mesothelioma, malignant of pleura, NOS
+∞
117.0
109
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
11.6
115.6
130
135
GAC01
NOMESCO Finland
Endoscopic biopsy of pleura
655.3
115.5
111
*
C38.4
ICD-10 Finland
Malignant neoplasm: Pleura
+∞
106.0
99
*
A04AA02
ATC
granisetron; systemic, transdermal
1082.5
98.6
94
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
17.6
94.6
80
51
JN4AD
NOMESCO Finland
Body CT examination
8.7
94.4
133
184
C38.1
ICD-10 Finland
Malignant neoplasm: Anterior mediastinum
+∞
88.4
83
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
951.3
87.6
84
*
L03AA02
ATC
filgrastim; parenteral
323.1
85.7
85
*
L03AA13
ATC
pegfilgrastim; parenteral
305.2
81.4
81
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
219.1
76.9
78
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
12.1
74.2
78
72
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
35.9
74.2
47
14
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
271.2
72.8
73
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
72.2
68
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
203.4
71.6
73
*
ZX120
NOMESCO Finland
Intravenous
6.7
71.0
126
222
GD1AD
NOMESCO Finland
Thorax CT examination
7.8
68.8
103
151
J94.9
ICD-10 Finland
Pleural condition, unspecified
33.5
68.0
44
14
C38.3
ICD-10 Finland
Malignant neoplasm: Mediastinum, part unspecified
+∞
67.8
64
*
XX3DW
NOMESCO Finland
Time consuming IT work
7.8
61.6
91
131
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
61.4
58
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
323.7
59.3
59
*
WW500
NOMESCO Finland
Blood transfusion
12.1
58.7
61
55
A04AA55
ATC
palonosetron, combinations; systemic
+∞
58.1
55
*
GAC00
NOMESCO Finland
Biopsy of pleura
98.8
57.9
63
7
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
605.5
57.5
56
*
L01CA04
ATC
vinorelbine; systemic
+∞
56.0
53
*
N02AA01
ATC
morphine; systemic, rectal
15.0
49.7
45
32
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
20.0
48.7
38
20
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
47.4
45
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
46.4
44
*
WF002
NOMESCO Finland
Radical radiotherapy
76.6
44.6
50
7
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
44.2
42
*
WZC30
NOMESCO Finland
Teaching
4.2
44.2
137
384
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
44.0
406
2211
WZC00
NOMESCO Finland
Treatment plan or consultation
3.2
42.8
236
963
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
443.4
42.6
42
*
1BA04, ,
NOMESCO Finland
+∞
42.1
40
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
42.1
40
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
96.1
41.3
45
5
D38.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pleura
409.5
39.5
39
*
JN4CD
NOMESCO Finland
Very extensive body CT
11.7
39.2
41
37
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
37.9
36
*
C45.9
ICD-10 Finland
Mesothelioma, unspecified
+∞
37.9
36
*
9051/3-C38.4
ICD-O-3
Fibrous mesothelioma, malignant of pleura, NOS
+∞
37.9
36
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
9.7
37.8
45
49
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.7
37.7
137
427
C38.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of heart, mediastinum and pleura
+∞
36.8
35
*
A04AD12
ATC
aprepitant; systemic
+∞
34.7
33
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.0
33.8
195
803
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.2
33.8
74
156
116
Kela drug reimbursment
Prostate cancer
+∞
33.6
32
*
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
12.8
33.5
33
27
J01MA14
ATC
moxifloxacin; systemic
3.9
32.8
108
313
J01MA12
ATC
levofloxacin; systemic
3.0
32.6
189
778
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
32.6
31
*
GAA31
NOMESCO Finland
Thoracoscopy
331.5
32.1
32
*
A06AH03
ATC
naloxegol; oral
50.1
31.9
38
8
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
73.4
31.2
35
5
AA1BD
NOMESCO Finland
Extensive CT of head and brain
9.3
30.9
38
43
R84
ICPC
Malignant neoplasm bronchus/lung
315.4
30.0
30
*
C83.33
ICD-10 Finland
Primary medical lymphoma with large B cells
+∞
29.4
28
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
29.4
28
*
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
+∞
29.4
28
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
83.8
29.0
32
*
8000/3-C34.9
ICD-O-3
Neoplasm, malignant of lung, NOS
+∞
28.3
27
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
28.2
193
860
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
292.7
28.0
28
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
151.1
27.8
29
*
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
11.6
27.7
29
26
TK800
NOMESCO Finland
Hemodialysis
7.8
27.0
38
51
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
26.2
25
*
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
26.2
25
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
270.1
25.9
26
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
25.2
24
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.5
24.8
36
50
H02AB06
ATC
prednisolone; systemic
2.3
24.4
362
2255
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
+∞
24.1
23
*
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
+∞
24.1
23
*
A79
ICPC
Malignancy NOS
+∞
24.1
23
*
L01CB01
ATC
etoposide; systemic
+∞
24.1
23
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
24.1
187
879
D70.82
ICD-10 Finland
Drug-induced neutropenia
90.0
23.8
26
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
23.1
279
1588
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
23.0
22
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
23.0
22
*
9679/3-C38.3
ICD-O-3
Mediastinal large B-cell lymphoma of mediastinum, NOS
+∞
23.0
22
*
L02AE02
ATC
leuprorelin; implant, parenteral
41.6
22.8
28
7
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
124.1
22.7
24
*
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
+∞
22.0
21
*
R85
ICPC
Malignant neopl respiratory other
+∞
22.0
21
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
22.0
21
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
22.0
21
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
44.9
21.5
26
6
B01AB05
ATC
enoxaparin; parenteral
2.3
21.0
223
1194
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
20.9
20
*
C34.00
ICD-10 Finland
Malignant tumor of the main bronchus without histology
+∞
20.9
20
*
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
5.1
20.9
45
93
Z2446
NOMESCO Finland
Social worker
3.8
20.8
67
190
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
8.2
20.1
27
34
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
19.9
19
*
GA2AT
NOMESCO Finland
Pleural biopsy with ultrasound guidance
+∞
19.9
19
*
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
+∞
19.9
19
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
19.9
19
*
115
Kela drug reimbursment
Breast cancer
+∞
19.9
19
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
205.6
19.7
20
*
GEA00
NOMESCO Finland
Mediastinoscopy
47.4
19.3
23
5
WX600
NOMESCO Finland
Single shot through catheter
20.8
19.2
28
14
L02BB03
ATC
bicalutamide; oral
+∞
18.8
18
*
9053/3-C38.4
ICD-O-3
Mesothelioma, biphasic, malignant of pleura, NOS
+∞
18.8
18
*
C37
ICD-10 Finland
Malignant neoplasm of thymus
+∞
18.8
18
*
GEB30
NOMESCO Finland
Mediastinotomy and excision of lesion
195.0
18.6
19
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.7
18.5
112
462
8000/3-C38.4
ICD-O-3
Neoplasm, malignant of pleura, NOS
+∞
17.8
17
*
9663/3-C38.3
ICD-O-3
Hodgkin lymphoma, nodular sclerosis, NOS, of mediastinum, NOS
+∞
17.8
17
*
C34.82
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary adenocarcinoma
+∞
17.8
17
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
17.8
17
*
Z51.0
ICD-10 Finland
Radiotherapy session
184.5
17.6
18
*
PJA12
NOMESCO Finland
Sentinel node biopsy
184.5
17.6
18
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
24.8
17.4
24
10
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
43.2
17.4
21
5
B01AB10
ATC
tinzaparin; parenteral
3.3
17.2
68
220
JN6AD
NOMESCO Finland
CT of torso and neck
22.5
17.0
24
11
C38.2
ICD-10 Finland
Malignant neoplasm: Posterior mediastinum
+∞
16.7
16
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
16.7
272
1688
QBC00
NOMESCO Finland
Removal of foreign body from skin of trunk or subcutaneous tissue
92.3
16.6
18
*
D38.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Thymus
174.0
16.6
17
*
N03AX16
ATC
[U] pregabalin
2.2
16.5
164
844
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
16.5
252
1528
R50.9
ICD-10 Finland
Fever, unspecified
2.5
16.2
118
530
N02AX02
ATC
tramadol; systemic, rectal
1.9
15.7
304
1990
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
15.7
15
*
9680/3-C38.3
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of mediastinum, NOS
+∞
15.7
15
*
C38.0
ICD-10 Finland
Malignant neoplasm: Heart
+∞
15.7
15
*
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
+∞
15.7
15
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
15.7
15
*
GDD20
NOMESCO Finland
Extended pneumonectomy
+∞
15.7
15
*
C45.1
ICD-10 Finland
Mesothelioma of peritoneum
+∞
15.7
15
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
15.7
15
*
C34.80
ICD-10 Finland
Malignant overall tumor of bronchus and lung without histology
+∞
15.7
15
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.6
15.7
54
160
GAC43
NOMESCO Finland
Total decortication of pleura
163.5
15.5
16
*
R06.0
ICD-10 Finland
Dyspnoea
2.0
15.3
225
1338
R4110
NOMESCO Finland
Physiotherapy
2.1
15.3
190
1064
B03BA03
ATC
hydroxocobalamin; parenteral
3.0
15.1
70
249
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.7
14.9
28
51
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
58.0
14.8
17
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
14.8
157
827
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
14.7
116
539
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
14.6
14
*
L01BC06
ATC
capecitabine; oral
+∞
14.6
14
*
R82
ICPC
Pleurisy/pleural effusion
81.9
14.6
16
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.0
14.6
69
248
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.0
14.6
26
45
XW000
NOMESCO Finland
Bone marrow biopsy
4.2
14.4
39
97
ZX112
NOMESCO Finland
Subcutaneous
17.4
14.4
22
13
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
22.8
14.3
20
9
ZXE00
NOMESCO Finland
One hour or less
1.9
14.1
259
1654
N05BA06
ATC
lorazepam; systemic, sublingual
3.2
13.8
57
189
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
4.3
13.8
36
87
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.5
13.8
92
396
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
15.1
13.6
22
15
C45
ICD-10 Finland
Mesothelioma
+∞
13.6
13
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
13.6
13
*
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
13.6
13
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
13.6
13
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
13.6
13
*
WX402
NOMESCO Finland
General anaesthesia
2.3
13.3
110
521
HA1AA
NOMESCO Finland
X-ray mammography
5.9
13.3
24
42
1XC02, ,
NOMESCO Finland
40.9
13.2
16
*
SPAT1109
SPAT
Analgesia with portable analgesic pump
29.0
13.0
17
6
WW200
NOMESCO Finland
Immunization
4.9
12.7
28
59
L02BG04
ATC
letrozole; oral
15.8
12.7
20
13
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
32.7
12.6
16
5
J86.9
ICD-10 Finland
Pyothorax without fistula
11.3
12.6
23
21
GAC30
NOMESCO Finland
Artificial pneumothorax
+∞
12.5
12
*
8041/3-C34.9
ICD-O-3
Small cell carcinoma, NOS, of lung, NOS
+∞
12.5
12
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
12.5
12
*
GEC23
NOMESCO Finland
Transsternal thymectomy
+∞
12.5
12
*
GDC00
NOMESCO Finland
Lobectomy of lung
132.3
12.5
13
*
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
132.3
12.5
13
*
I31.3
ICD-10 Finland
Pericardial effusion (noninflammatory)
132.3
12.5
13
*
WW200, ,
SPAT
0.3
12.4
29
971
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
18.4
12.1
18
10
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.8
12.0
22
39
Z3231
NOMESCO Finland
Registered nurse
1.9
12.0
183
1091
A02BC02
ATC
pantoprazole; systemic
1.8
11.9
426
3270
Z2221
NOMESCO Finland
Medical doctor
1.9
11.9
178
1052
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.1
11.9
5
427
GAC97
NOMESCO Finland
Other endoscopic operation on pleura
30.6
11.7
15
5
NK6AN
NOMESCO Finland
Total body bone isotope imaging
66.1
11.6
13
*
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
4.5
11.5
28
64
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
11.5
11
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
11.5
11
*
GDD96
NOMESCO Finland
Other pneumonectomy
+∞
11.5
11
*
C34.19
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung other or unspecified histology
+∞
11.5
11
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
11.5
11
*
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
11.5
11
*
L02BA01
ATC
tamoxifen; oral
121.9
11.5
12
*
GA3AT
NOMESCO Finland
Pleural cytology with ultrasound guidance
18.2
10.8
16
9
GAC37
NOMESCO Finland
Endoscopic chemical pleurodesis
111.6
10.4
11
*
8070/3-C32.9
ICD-O-3
Squamous cell carcinoma, NOS, of larynx, NOS
+∞
10.4
10
*
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
+∞
10.4
10
*
Z85.7
ICD-10 Finland
Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
+∞
10.4
10
*
GD2FN
NOMESCO Finland
Lung ventilation distribution isotope examination (radiospirometry)
+∞
10.4
10
*
GA2CT
NOMESCO Finland
Pleural biopsy with CT guidance
+∞
10.4
10
*
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
+∞
10.4
10
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
10.4
10
*
A04AA03
ATC
tropisetron; systemic
+∞
10.4
10
*
R4190
NOMESCO Finland
Nutritional therapy
4.8
10.3
23
49
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.7
9.9
53
204
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.6
9.6
32
93
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.4
9.6
35
108
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.2
9.6
18
18
D15.0
ICD-10 Finland
Benign neoplasm: Thymus
101.4
9.4
10
*
GAC46
NOMESCO Finland
Partial decortication of pleura
101.4
9.4
10
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
101.4
9.4
10
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
101.4
9.4
10
*
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
9.4
9
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
9.4
9
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
9.4
9
*
GAC20
NOMESCO Finland
Excision or destruction of lesion of pleura
+∞
9.4
9
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
9.4
9
*
8580/3-C37.9
ICD-O-3
Thymoma, NOS, of thymus
+∞
9.4
9
*
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
+∞
9.4
9
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
9.4
9
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
10.9
9.3
17
16
N06DA02
ATC
donepezil; oral
0.2
9.3
6
381
N05CF01
ATC
zopiclone; oral
1.7
9.3
230
1566
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
4.5
9.1
22
50
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.8
9.1
45
166
GEC24
NOMESCO Finland
Thoracoscopic thymectomy
37.2
9.0
11
*
M79.6
ICD-10 Finland
Pain in limb
0.5
8.8
101
1730
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
3.6
8.7
29
84
GEA20
NOMESCO Finland
Mediastinoscopy with excision of lesion
50.6
8.7
10
*
TGC00
NOMESCO Finland
Bronchial lavation
3.9
8.6
25
66
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
16.5
8.6
13
8
B01AB04
ATC
dalteparin; parenteral
3.0
8.5
37
127
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
27.9
8.5
11
*
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
91.1
8.4
9
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
91.1
8.4
9
*
Y77
ICPC
Malignant neoplasm prostate
91.1
8.4
9
*
A98
ICPC
Health maint/preventive medicine
0.6
8.4
458
5293
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
8.3
8
*
1638X
ICD-9 Finland
Malignant neoplasm of pleura, Other specified sites of pleura
+∞
8.3
8
*
C34.92
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary adenocarcinoma
+∞
8.3
8
*
128
Kela drug reimbursment
Cancers of female genital organs
+∞
8.3
8
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
8.3
8
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
8.3
8
*
8000/3-C38.3
ICD-O-3
Neoplasm, malignant of mediastinum, NOS
+∞
8.3
8
*
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
+∞
8.3
8
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
8.3
8
*
C34.89
ICD-10 Finland
Malignant overall tumor of the bronchus and lung other or unspecified histology
+∞
8.3
8
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.7
8.3
45
174
C10AA07
ATC
rosuvastatin; oral
0.5
8.1
74
1372
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
17.4
8.1
12
7
J93.9
ICD-10 Finland
Pneumothorax, unspecified
17.4
8.1
12
7
XX1XW
NOMESCO Finland
Extensive written report from radiologist
4.2
8.0
21
51
TGD00
NOMESCO Finland
Needle biopsy of lung
22.3
8.0
11
5
P20
ICPC
Memory disturbance
0.4
7.8
33
832
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
45.5
7.7
9
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
45.5
7.7
9
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
18.6
7.6
11
6
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
6.6
7.4
18
28
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
80.9
7.4
8
*
I87.1
ICD-10 Finland
Compression of vein
80.9
7.4
8
*
GAC36
NOMESCO Finland
Chemical pleurodesis
80.9
7.4
8
*
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
13.5
7.4
12
9
1649X
ICD-9 Finland
Malignant neoplasm of thymus, heart and mediastinum, Mediastinum, part unspecified
+∞
7.3
7
*
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
+∞
7.3
7
*
C80.92
ICD-10 Finland
Malignant tumor without specified localization adenocarcinoma
+∞
7.3
7
*
Z08.9
ICD-10 Finland
Follow-up examination after unspecified treatment for malignant neoplasm
+∞
7.3
7
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
7.3
7
*
C78.1
ICD-10 Finland
Secondary malignant neoplasm of mediastinum
+∞
7.3
7
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
7.3
7
*
C83.00
ICD-10 Finland
Lymphocytic lymphoma
+∞
7.3
7
*
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
+∞
7.3
7
*
159
Kela drug reimbursment
Pazopanib
+∞
7.3
7
*
XX9CD
NOMESCO Finland
Very extensive complementary CT
+∞
7.3
7
*
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
+∞
7.3
7
*
GWE00
NOMESCO Finland
Reoperation for deep haemorrhage in thoracic surgery
+∞
7.3
7
*
C34.39
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other or unspecified histology
+∞
7.3
7
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
7.3
7
*
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
7.4
7.2
16
22
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
7.2
74
381
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
20.3
7.1
10
5
ZZR00
NOMESCO Finland
Flap of skin
20.3
7.1
10
5
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.1
7.1
*
280
N06DX01
ATC
memantine; oral
0.2
6.8
13
498
A06AD11
ATC
lactulose; oral
1.7
6.7
122
756
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
22.8
6.7
9
*
H02AB07
ATC
prednisone; oral
1.9
6.7
93
532
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.6
290
2223
I10
ICD-10 Finland
Essential (primary) hypertension
0.7
6.6
284
3559
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
6.3
6.5
16
26
SPAT1053
SPAT
Memory test
0.4
6.5
38
833
C90.0
ICD-10 Finland
Multiple myeloma
70.5
6.4
7
*
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
70.5
6.4
7
*
GDB10
NOMESCO Finland
Wedge resection of lung
70.5
6.4
7
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
0.6
6.4
137
2004
C10AA05
ATC
atorvastatin; oral
0.6
6.4
166
2321
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.2
6.3
24
76
C34.86
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary microcellular carcinoma
+∞
6.3
6
*
C34.0
ICD-10 Finland
Malignant neoplasm: Main bronchus
+∞
6.3
6
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
6.3
6
*
R92
ICPC
Neoplasm respiratory unspecified
+∞
6.3
6
*
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
+∞
6.3
6
*
8010/3-C34.9
ICD-O-3
Carcinoma, NOS, of lung, NOS
+∞
6.3
6
*
9680/3-C38.4
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of pleura, NOS
+∞
6.3
6
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
6.3
6
*
GDA21
NOMESCO Finland
Thoracoscopic excision of lesion of lung
+∞
6.3
6
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
C32.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of larynx
+∞
6.3
6
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
6.3
6
*
C45.7
ICD-10 Finland
Mesothelioma of other sites
+∞
6.3
6
*
C32.0
ICD-10 Finland
Malignant neoplasm: Glottis
+∞
6.3
6
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
6.3
6
*
GEW99
NOMESCO Finland
Other operation on mediastinum
+∞
6.3
6
*
FFA10
NOMESCO Finland
Excision of lesion of atrium
+∞
6.3
6
*
GCA32
NOMESCO Finland
Endoscopic insertion of stent into bronch
+∞
6.3
6
*
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
0.4
6.3
37
810
TGE00
NOMESCO Finland
Needle biopsy of mediastinum
26.9
6.2
8
*
J93.8
ICD-10 Finland
Other pneumothorax
12.7
6.1
10
8
KCD02
NOMESCO Finland
Transurethral resection of bladder
10.1
6.0
11
11
Z31.6
ICD-10 Finland
General counselling and advice on procreation
10.1
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
230
119
28.33
310.17
1.6
1.2
—
—
—
0
0
177
43
54.81
302.81
2.2
1.5
—
—
—
0
0
194
69
38.55
299.19
1.8
1.5
40.13
26.63
g/l
12.66
185
63
168
53
41.43
267.64
1.8
1.5
—
—
—
0
0
173
63
36.18
263.70
1.9
1.5
1943.39
1981.31
e6/l
0.02
136
45
166
58
37.24
256.14
1.9
1.6
53497.70
137868.53
e6/l
0.38
117
36
127
49
31.46
188.13
1.6
1.3
4.57
6.82
mmol/l
5.03
120
44
124
52
28.78
178.12
1.9
1.6
—
—
—
0
0
162
233
8.75
112.06
2.2
1.4
14.47
2.72
ug/l
0.59
129
165
75
31
26.99
107.19
1.5
1.3
—
—
—
0
0
245
712
4.76
79.18
2.3
2.1
—
—
—
0
0
228
697
4.37
67.76
5.4
2.6
0.78
0.83
mmol/l
9.42
218
645
307
1448
3.00
43.15
6.3
4.0
—
—
—
0
0
282
1340
2.85
38.12
2.7
1.6
—
—
—
0
0
373
2062
2.74
37.31
8.7
5.0
0.56
0.65
%
2.76
368
1909
376
2125
2.67
35.39
8.7
5.0
2.39
2.97
%
5.87
371
1966
376
2133
2.65
35.00
8.9
5.3
9.52
8.84
%
3.29
369
1977
379
2182
2.61
33.86
8.8
5.2
20.62
26.16
%
16.98
373
2030
422
2562
2.64
33.69
19.4
5.7
4.67
4.50
e9/l
0.49
379
2208
40
9
46.98
33.14
1.3
1.0
—
—
—
0
0
47
65
7.68
32.58
2.3
2.6
—
—
—
0
0
384
2288
2.51
30.98
8.2
4.9
0.70
0.62
e9/l
5.62
337
1960
384
2295
2.50
30.67
8.2
4.9
0.04
0.04
e9/l
1.70
339
1974
106
318
3.75
30.57
1.3
1.1
—
—
—
0
0
361
2104
2.48
30.38
9.5
5.3
—
—
—
0
0
387
2338
2.47
29.95
8.3
5.0
1.47
1.80
e9/l
11.49
344
2048
386
2366
2.41
28.40
8.9
5.1
0.17
0.21
e9/l
2.45
346
2049
31
31
10.42
27.56
2.2
1.2
—
—
—
0
0
345
2048
2.35
26.85
6.8
3.7
31.62
35.25
g/l
18.56
330
1880
383
2400
2.32
25.97
10.2
5.8
1.21
1.21
mmol/l
0.36
348
2041
80
228
3.83
24.69
1.3
1.4
—
—
—
0
0
258
1400
2.34
24.16
5.3
3.0
7.40
7.40
ph
0.39
38
237
222
1137
2.40
23.65
8.8
3.6
85.45
81.94
%
1.39
217
1101
208
1039
2.43
23.40
13.8
4.3
—
—
—
0
0
352
2198
2.21
23.20
9.8
5.6
1.21
1.20
mmol/l
0.41
343
1952
252
1392
2.27
22.27
3.3
2.1
—
—
—
0
0
127
520
2.76
21.40
1.5
1.4
—
—
—
0
0
207
1068
2.33
21.37
3.1
2.1
—
—
—
0
0
328
4554
0.47
20.73
5.0
6.4
40.54
40.92
mmol/mol
0.32
290
4154
184
915
2.37
20.58
6.1
2.1
2.50
2.44
mmol/l
11.51
170
772
375
2523
2.05
19.02
10.4
19.7
1.16
1.42
inr
7.10
77
710
260
1540
2.10
18.58
7.7
2.0
2.36
2.35
mmol/l
1.44
239
1266
368
4846
0.49
18.53
3.7
5.3
2.60
2.55
mmol/l
0.46
314
4380
350
4672
0.50
18.06
3.5
4.6
1.43
1.40
mmol/l
0.66
304
4217
359
4724
0.51
17.14
3.4
4.6
4.44
4.37
mmol/l
0.65
314
4293
16
0
+∞
16.73
8.0
0.0
0.25
—
umol/l
—
16
0
36
78
4.81
15.80
1.7
2.1
69.61
14.94
u/ml
0.45
31
57
38
88
4.51
15.40
1.8
1.4
9.08
7.96
u/l
0.26
32
75
346
4513
0.54
14.36
3.3
4.2
1.23
1.27
mmol/l
0.49
296
4036
127
634
2.23
13.58
11.3
7.5
1.50
1.33
mmol/l
0.22
115
497
21
14
15.42
13.16
5.5
1.9
3.19
4.10
nmol/l
0.29
21
14
224
1398
1.89
12.85
4.3
2.6
30.91
35.28
u/l
1.14
215
1326
118
590
2.20
12.51
1.6
1.7
—
—
—
0
0
68
264
2.75
12.49
17.5
11.8
—
—
—
0
0
303
2100
1.78
12.21
3.5
2.3
—
—
—
0
0
24
46
5.37
12.08
4.1
2.4
1.83
1.32
%
0.24
24
38
23
23
10.30
12.06
2.3
2.8
32.84
47.08
%
3.14
23
23
75
317
2.53
11.62
5.4
3.5
1.39
0.72
%
1.26
46
91
87
400
2.34
11.22
1.4
1.5
—
—
—
0
0
69
286
2.57
11.13
4.7
4.5
—
—
—
0
0
71
301
2.51
10.93
5.6
3.5
0.16
0.05
%
1.04
43
73
82
373
2.36
10.82
4.8
4.3
7.41
7.39
ph
—
7
41
18
14
13.16
10.69
2.2
3.1
0.08
0.16
e9/l
0.83
18
14
121
655
2.03
10.33
5.7
4.9
1.01
1.03
mmol/l
0.28
115
593
96
481
2.15
10.04
1.5
1.5
—
—
—
0
0
159
953
1.87
10.03
2.1
1.7
1.82
1.37
mg/l
1.08
131
732
97
1740
0.49
10.00
2.4
3.2
8.34
7.76
mmol/l
0.59
80
1452
66
283
2.47
9.91
4.6
3.5
0.86
0.53
%
0.67
40
79
15
9
17.00
9.91
3.6
1.1
73.60
68.44
nmol/l
—
15
9
393
4771
0.60
9.88
4.3
4.8
6.08
6.11
mmol/l
0.14
347
4253
93
1686
0.48
9.86
2.3
3.3
17.93
147.59
mg/l
1.71
55
1113
59
1267
0.42
9.84
1.4
1.6
1.43
1.32
mmol/l
0.57
53
1038
101
1773
0.50
9.71
2.9
3.8
2.26
9.07
mg/mmol
8.77
55
1158
202
1315
1.75
9.64
2.9
2.8
—
—
—
0
0
35
108
3.36
9.56
1.5
2.0
8.85
11.82
mg/l
1.45
35
98
223
1504
1.71
9.32
3.1
3.0
22.64
112.02
e6/l
1.34
172
1151
27
72
3.86
9.13
2.4
1.9
123.26
7748.66
u/l
—
10
20
87
435
2.14
9.13
15.4
7.5
—
—
—
0
0
446
3603
1.66
9.13
16.1
5.1
85.62
76.22
u/l
4.47
439
3301
12
5
24.36
8.93
1.2
1.0
25.07
10.28
g/l
—
12
5
171
1086
1.76
8.79
5.0
4.0
169.66
416.99
ng/l
1.73
153
914
205
1370
1.70
8.78
2.9
2.9
0.60
0.36
e6/l
0.63
154
1030
14
10
14.25
8.72
2.0
3.9
5.07
6.60
%
—
14
10
14
10
14.25
8.72
1.9
3.9
—
—
—
0
0
56
238
2.47
8.58
5.3
5.0
26.09
24.75
mmol/l
2.18
56
220
283
2067
1.62
8.52
15.8
8.0
0.00
0.00
e9/l
0.39
219
1664
79
391
2.15
8.50
2.4
2.1
32.40
30.70
u/l
0.21
68
310
111
623
1.93
8.47
12.2
6.3
103.55
104.58
mmol/l
1.30
111
623
377
2961
1.59
8.31
9.0
4.7
6.65
6.88
mmol/l
1.57
366
2771
63
287
2.31
8.28
5.5
3.6
0.09
0.03
%
0.53
33
62
20
31
6.61
8.23
1.3
1.1
—
—
—
0
0
13
11
12.02
7.60
2.2
1.0
—
—
—
0
0
72
361
2.11
7.50
1.4
1.5
—
—
—
0
0
31
105
3.04
7.32
3.2
3.2
—
—
—
0
0
30
102
3.03
7.04
1.5
2.6
—
—
—
0
0
476
5361
0.65
6.32
46.9
20.1
125.40
136.03
g/l
33.60
467
5228
476
5360
0.65
6.30
46.4
20.0
7.57
6.89
e9/l
3.13
458
5144
476
5360
0.65
6.30
47.8
20.1
38.17
40.11
%
11.26
444
4887
476
5359
0.65
6.28
46.3
20.0
4.27
4.48
e12/l
13.59
458
5139
476
5359
0.65
6.28
46.1
19.9
29.75
30.50
pg
14.26
466
5228
476
5358
0.65
6.25
46.2
19.9
90.63
91.57
fl
4.14
466
5227
476
5356
0.65
6.21
46.3
20.0
275.87
237.22
e9/l
16.40
460
5161
151
1013
1.63
6.12
2.5
2.6
544.31
555.24
mosm/kgh2o
0.25
135
844
34
135
2.60
6.03
4.3
4.0
—
—
—
0
0
231
1717
1.52
5.96
3.5
3.4
106.63
85.51
e6/l
0.15
176
1218
375
4406
0.68
5.89
5.2
4.2
2.24
1.99
mu/l
1.17
337
3926
17
35
4.95
5.77
5.8
2.7
—
—
—
0
0
64
1113
0.53
5.55
4.0
3.9
1.02
1.02
kg/l
—
9
171
27
101
2.74
5.39
2.9
2.1
14.73
16.31
%
0.81
14
54
16
34
4.79
5.33
1.4
1.1
—
—
—
0
0
9
8
11.38
5.30
1.0
1.0
—
—
—
0
0
232
1762
1.47
5.27
3.4
3.1
1247.02
1818.71
ng/l
2.03
219
1514
82
485
1.78
5.26
2.8
2.1
6.45
9.69
umol/l
1.47
73
418
21
70
3.06
5.14
1.2
1.4
—
—
—
0
0
104
668
1.65
4.96
2.0
2.4
19.24
23.11
%
2.04
96
562
13
24
5.50
4.93
5.3
3.0
—
—
—
0
0
12
21
5.79
4.77
1.3
1.0
—
—
—
0
0
118
795
1.58
4.63
2.9
2.7
2.40
1.80
e6/l
0.29
60
430
197
1481
1.46
4.62
3.5
2.2
52.88
59.99
u/l
1.22
190
1353
7
5
14.12
4.58
2.4
3.0
—
—
—
0
0
7
5
14.12
4.58
4.9
6.0
—
—
—
0
0
21
76
2.82
4.48
4.9
2.9
63.05
58.68
%
0.68
21
76
117
794
1.57
4.45
2.0
2.3
9.80
12.70
umol/l
4.95
111
723
14
41
3.46
4.20
1.4
1.2
—
—
—
0
0
175
2265
0.70
4.11
1.6
2.1
94.82
92.15
pmol/l
0.28
102
1190
22
499
0.42
4.06
1.8
1.6
—
—
—
0
0
161
1191
1.46
4.05
1.5
1.3
—
—
—
0
0
144
1043
1.48
4.03
2.5
2.3
3.86
4.19
e6/l
0.26
134
932
11
22
5.06
4.01
2.7
2.6
38.83
47.08
%
—
6
13
451
5005
0.72
4.01
27.2
13.4
—
—
—
0
0
20
76
2.68
3.93
4.1
2.6
4.09
4.38
e9/l
0.29
20
76
210
2615
0.72
3.86
4.7
4.0
2.41
2.13
ug/l
0.67
177
2314
465
5117
0.73
3.73
19.5
8.8
25.28
25.52
u/l
0.11
456
4852
87
574
1.59
3.73
1.3
1.3
396.19
522.11
titre
0.56
21
133
14
39
3.64
3.71
5.1
2.9
—
—
—
0
0
104
716
1.53
3.70
2.0
2.3
2.10
2.24
g/l
1.68
99
651
103
1442
0.66
3.60
2.6
3.2
—
—
—
0
0
468
5130
0.73
3.51
35.0
17.2
4.01
4.01
mmol/l
0.17
457
4949
74
479
1.61
3.44
5.9
3.6
—
—
—
0
0
468
5122
0.74
3.40
34.9
17.1
138.45
139.76
mmol/l
16.00
459
4946
23
105
2.23
3.12
3.1
2.9
—
—
—
0
0
12
36
3.37
3.03
4.0
2.1
57.58
57.37
%
0.01
12
30
9
21
4.33
3.00
1.2
1.1
—
—
—
0
0
6
9
6.71
2.87
1.5
2.4
—
—
—
0
0
40
231
1.78
2.86
1.2
1.3
—
—
—
0
0
87
1207
0.68
2.86
1.5
1.7
561.71
4094582.95
pmol/l
0.50
69
977
362
3183
1.29
2.75
4.4
4.4
170.45
806.58
e6/l
0.64
11
53
56
361
1.60
2.69
1.2
1.4
—
—
—
0
0
165
1312
1.34
2.63
3.7
2.6
2066.64
8863.66
umol/l
2.22
149
1115
92
667
1.44
2.56
3.6
2.0
1.64
1.72
%
0.29
84
582
12
44
2.76
2.55
1.7
1.1
—
—
—
0
0
17
75
2.30
2.52
1.4
1.3
—
—
—
0
0
309
3504
0.79
2.50
4.6
3.4
15.06
14.96
pmol/l
0.28
286
3103
14
57
2.49
2.46
2.5
1.5
89.15
89.95
%
0.27
14
57
20
96
2.12
2.45
1.5
1.2
—
—
—
0
0
361
4015
0.79
2.44
40.4
18.3
328.06
332.60
g/l
16.21
354
3971
40
243
1.69
2.43
4.8
3.4
24.99
24.17
mmol/l
0.71
40
235
24
124
1.97
2.43
2.4
2.1
120.07
133.30
g/l
0.99
14
90
12
46
2.64
2.37
1.3
1.2
—
—
—
0
0
10
33
3.06
2.36
1.1
1.1
2.05
6.51
nmol/l
—
5
7
20
98
2.07
2.33
1.7
1.7
346.85
278.94
mu/l
0.48
20
90
7
18
3.92
2.25
1.3
1.1
—
—
—
0
0
77
554
1.44
2.25
1.8
1.8
—
—
—
0
0
197
2334
0.78
2.23
3.4
3.6
0.00
0.00
estimate
0.50
48
428
12
48
2.53
2.19
1.2
1.4
92.33
63.36
pmol/l
0.92
12
48
155
1889
0.77
2.19
3.3
3.4
6.10
5.96
ph
—
10
83
57
394
1.49
2.05
3.8
5.9
—
—
—
0
0
90
1174
0.73
2.05
1.6
1.8
1250.45
1155.11
nmol/l
0.35
61
869
5
145
0.34
2.03
1.2
1.1
—
—
—
0
0
107
1357
0.75
2.01
1.3
1.5
21.62
19.93
nmol/l
0.52
98
1131
5
11
4.57
1.94
1.8
1.5
33.00
56.46
ug/l
—
5
11
201
2345
0.80
1.94
3.4
3.6
0.00
0.00
estimate
-0.00
46
389
199
2315
0.80
1.85
4.7
4.8
0.00
0.00
estimate
-0.00
46
392
44
297
1.51
1.80
3.4
2.8
5.00
5.31
e9/l
0.14
33
221
91
1156
0.76
1.73
2.9
3.6
—
—
—
0
0
7
24
2.94
1.72
1.7
2.5
807.43
652.75
u/ml
—
7
24
11
48
2.31
1.71
2.4
1.2
—
—
—
0
0
104
1295
0.77
1.71
3.7
3.8
0.00
0.00
estimate
-0.00
43
378
8
31
2.60
1.66
1.1
1.1
—
—
—
0
0
157
1846
0.81
1.58
2.2
2.2
76.78
77.69
nmol/l
0.15
138
1576
72
548
1.35
1.56
2.4
2.6
9.50
6.82
ug/l
0.36
59
469
12
57
2.12
1.55
1.2
1.2
—
—
—
0
0
21
345
0.60
1.55
2.5
2.8
—
—
—
0
0
8
33
2.44
1.54
1.8
1.7
—
—
—
0
0
17
93
1.85
1.52
2.0
1.1
—
—
—
0
0
9
184
0.48
1.52
17.0
10.1
—
—
—
0
0
0
45
0.00
1.50
0.0
1.0
—
323.07
—
0
29
20
117
1.73
1.46
1.5
1.2
—
—
—
0
0
14
73
1.94
1.44
5.2
1.5
—
—
—
0
0
5
16
3.14
1.44
1.4
1.4
—
—
—
0
0
34
232
1.49
1.37
3.6
6.3
1.62
1.66
%
0.12
34
224
7
148
0.47
1.33
1.4
1.6
—
—
—
0
0
70
880
0.77
1.25
1.2
1.2
0.97
1.40
u/ml
0.48
12
224
63
488
1.32
1.25
3.7
2.1
57.63
67.18
e9/l
1.38
43
385
8
38
2.12
1.18
1.0
1.2
—
—
—
0
0
34
240
1.44
1.18
1.3
1.7
1.89
1.50
g/l
1.03
28
205
30
423
0.70
1.14
1.2
1.3
—
—
—
0
0
33
457
0.71
1.14
1.7
2.1
188.13
188.04
ug/g
0.00
27
345
22
144
1.54
1.10
1.0
1.2
—
—
—
0
0
32
227
1.43
1.10
5.8
6.5
0.80
0.88
%
0.61
32
219
49
374
1.33
1.09
1.8
1.5
—
—
—
0
0
15
90
1.68
1.04
1.7
1.4
81.10
63.58
mmol/l
—
10
72
67
542
1.26
0.99
2.3
3.2
180.37
270.91
ng/l
1.92
57
502
9
49
1.85
0.99
1.1
1.1
—
—
—
0
0
383
4058
0.88
0.98
40.0
15.8
15.19
15.08
%
0.17
376
3964
17
259
0.65
0.98
2.2
2.4
—
—
—
0
0
7
36
1.95
0.97
1.3
1.2
—
—
—
0
0
11
185
0.59
0.95
1.9
1.4
—
—
—
0
0
7
37
1.90
0.94
1.7
1.6
—
—
—
0
0
7
37
1.90
0.94
2.6
2.9
—
—
—
0
0
19
277
0.68
0.90
1.0
1.3
—
—
—
0
0
5
102
0.49
0.90
1.2
1.9
220.60
222.38
pmol/l
—
5
97
36
469
0.75
0.88
2.1
3.1
—
—
—
0
0
16
240
0.66
0.87
1.3
1.4
—
—
—
0
0
92
787
1.19
0.83
1.8
1.3
2.03
2.70
g/l
2.29
63
447
6
32
1.88
0.82
2.5
2.4
—
—
—
0
0
30
224
1.35
0.81
1.1
1.2
62.11
102.71
iu/ml
—
7
89
8
47
1.71
0.81
1.0
1.2
—
—
—
0
0
18
122
1.49
0.80
8.6
2.7
1.13
1.65
mg/l
3.13
18
106
0
25
0.00
0.79
0.0
3.2
—
30.59
—
0
17
5
99
0.50
0.78
1.0
1.6
—
—
—
0
0
5
100
0.50
0.77
1.0
1.7
—
—
—
0
0
5
100
0.50
0.77
1.0
1.6
—
—
—
0
0
5
100
0.50
0.77
1.0
1.6
—
—
—
0
0
128
1439
0.86
0.77
3.0
2.8
0.86
0.76
ug/l
0.52
88
1002
17
115
1.49
0.77
2.0
1.3
24.80
1170.58
e6/l
—
10
100
17
115
1.49
0.77
2.1
1.3
34.00
70.74
e6/l
—
10
98
0
28
0.00
0.76
0.0
1.0
—
—
—
0
0
9
53
1.71
0.75
1.3
1.2
—
—
—
0
0
5
24
2.09
0.74
1.8
1.4
8.80
10.67
mmol/l
—
5
24
8
132
0.60
0.74
4.0
2.4
—
—
—
0
0
8
133
0.60
0.74
1.3
1.8
40.25
42.32
nmol/l
—
8
125
5
95
0.52
0.66
1.0
1.7
—
—
—
0
0
16
111
1.45
0.66
2.0
1.3
4.17
4.00
mmol/l
0.14
16
102
12
78
1.55
0.66
1.0
1.2
—
—
—
0
0
5
30
1.67
0.61
1.4
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
10.5
—
0.63
—
0
20
0
22
0.00
0.59
0.0
11.5
—
805.41
—
0
22
0
22
0.00
0.59
0.0
15.6
—
1383.86
—
0
22
13
90
1.45
0.55
1.2
1.7
—
—
—
0
0
6
38
1.58
0.54
1.2
1.6
—
—
—
0
0
349
3338
1.09
0.54
4.2
4.1
—
—
—
0
0
9
61
1.48
0.54
1.1
1.0
—
—
—
0
0
469
4830
0.91
0.53
36.5
13.9
43.44
26.49
mg/l
14.77
443
3748
20
153
1.32
0.50
3.5
3.8
—
—
—
0
0
46
390
1.19
0.50
3.5
3.5
—
—
—
0
0
68
598
1.15
0.49
1.2
1.2
—
—
—
0
0
25
311
0.80
0.48
1.1
1.2
—
—
—
0
0
12
85
1.42
0.47
1.1
1.4
184.00
241.87
miu/ml
—
5
37
7
48
1.46
0.47
1.1
1.4
—
—
—
0
0
43
366
1.19
0.46
2.2
1.9
0.18
0.20
g/l
0.98
43
320
5
84
0.59
0.45
1.2
1.4
—
—
—
0
0
369
3556
1.08
0.45
4.7
3.9
23.84
12.40
mm/h
11.86
354
3214
225
2128
1.08
0.44
4.6
4.1
37.51
82.25
ng/l
1.10
185
1604
14
185
0.75
0.43
2.8
1.8
—
—
—
0
0
16
122
1.32
0.42
4.5
3.6
33.92
28.13
mg/l
0.31
11
87
6
91
0.66
0.42
1.0
1.1
35.42
20.06
u/l
—
6
81
5
33
1.52
0.41
3.8
3.6
8.60
7.25
mmol/l
—
5
19
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
20.50
—
0
10
7
101
0.69
0.39
1.1
1.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
38.39
—
0
10
16
125
1.29
0.37
1.4
1.2
—
—
—
0
0
112
1203
0.92
0.34
3.6
3.2
—
—
—
0
0
31
265
1.18
0.34
1.5
1.3
—
—
—
0
0
20
242
0.82
0.33
4.8
4.8
—
—
—
0
0
20
164
1.23
0.33
1.3
1.2
—
—
—
0
0
15
187
0.80
0.32
1.5
2.5
0.28
0.23
g/l
—
7
61
7
52
1.35
0.31
2.4
1.3
—
—
—
0
0
49
440
1.12
0.29
6.4
3.0
4.81
4.45
kpa
0.39
49
421
15
121
1.24
0.28
4.1
1.5
—
—
—
0
0
145
1377
1.07
0.27
1.9
2.1
3.43
2.96
mg/l
1.41
125
1147
76
704
1.09
0.26
1.2
1.3
24.46
42.36
iu/ml
1.09
16
203
9
73
1.24
0.25
1.1
1.0
—
—
—
0
0
10
78
1.29
0.24
2.9
2.4
—
—
—
0
0
190
1974
0.95
0.23
2.7
2.6
387.99
141.91
ug/l
4.14
177
1782
5
40
1.25
0.22
1.4
1.1
—
285.71
—
0
7
5
41
1.22
0.22
1.2
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
0.69
—
0
5
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
7.5
—
—
—
0
0
0
13
0.00
0.21
0.0
8.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
94.08
—
0
8
14
117
1.20
0.20
1.3
1.1
—
—
—
0
0
6
53
1.13
0.18
1.2
1.4
—
—
—
0
0
6
53
1.13
0.18
1.2
1.4
—
—
—
0
0
14
119
1.18
0.18
8.4
10.2
102.71
105.79
mmol/l
1.73
14
112
14
119
1.18
0.18
8.4
10.2
10.57
11.48
mmol/l
0.47
14
112
22
195
1.13
0.17
1.9
1.9
—
—
—
0
0
70
664
1.06
0.15
1.2
1.3
27.16
12.12
u/ml
0.44
17
237
9
82
1.10
0.15
7.1
2.3
65.67
63.43
%
—
9
82
11
127
0.86
0.12
1.0
1.1
—
—
—
0
0
11
126
0.87
0.11
2.0
1.6
—
—
—
0
0
26
278
0.93
0.09
1.3
1.6
—
—
—
0
0
6
56
1.07
0.08
1.2
1.5
—
—
—
0
0
151
1541
0.97
0.08
5.1
4.1
—
—
—
0
0
5
63
0.79
0.08
2.4
2.7
—
—
—
0
0
282
2854
0.98
0.08
4.4
2.9
59.53
49.86
u/l
0.95
269
2594
27
285
0.95
0.06
3.8
3.3
—
—
—
0
0
145
1462
0.99
0.02
2.8
3.1
—
—
—
0
0
29
282
1.03
0.02
3.4
2.5
0.17
0.20
e6/l
0.15
29
275
37
374
0.99
0.00
2.2
3.7
79.95
95.10
ng/l
0.45
30
327
11
111
0.99
0.00
6.0
2.9
—
—
—
0
0
348
3482
1.00
0.00
4.1
4.1
—
—
—
0
0
0
9
0.00
0.00
0.0
2.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
5.39
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
15.56
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
52
0.96
-0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
170.33
—
0
6
0
8
0.00
-0.00
0.0
5.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_HEART_MEDIASTINUM_PLEURA_WIDE – Malignant neoplasm of heart, mediastinum and pleura, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).