Acne

L12_ACNE

acne: An inflammatory process of the sebaceous glands which is characterized by comedones, nodules, papules and/or pustules on the skin.

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L70
  • Cause of death: ICD-10 L70

2 out of 7 registries used, show all original rules.

4744

4. Check minimum number of events

None

4744

5. Include endpoints

5052

6. Filter based on genotype QC (FinnGen only)

4812

Control definitions (FinnGen only)

Control exclude
L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L60-L75
Name in latin
Acne

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 52364 25973 26178
Only index persons 51216 25574 25642
Unadjusted period prevalence (%)
Whole population 0.74 0.74 0.73
Only index persons 0.96 0.94 0.98
Median age at first event (years)
Whole population 20.29 21.46 19.05
Only index persons 20.23 21.46 19.00

-FinnGen-

Key figures

All Female Male
Number of individuals 4812 3153 1659
Unadjusted period prevalence (%) 0.99 1.12 0.76
Median age at first event (years) 24.57 26.72 20.49

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
5052
Matched controls
50440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E0000UV, ,
ATC
3.0
312.4
2913
15772
L70.1
ICD-10 Finland
Acne conglobata
71.3
307.7
315
47
L70.8
ICD-10 Finland
Other acne
40.4
307.7
272
71
L70
ICD-10 Finland
Acne
12.1
307.7
1189
1256
J01AA04
ATC
lymecycline; systemic
7.7
307.7
2274
4845
G03HB01
ATC
cyproterone and estrogen; oral
4.2
307.7
1308
3900
D10BA01
ATC
isotretinoin; oral
19.0
307.7
2870
3270
L73.2
ICD-10 Finland
Hidradenitis suppurativa
26.2
307.7
236
94
J01AA07
ATC
tetracycline; systemic
7.5
307.7
2232
4815
L70.0
ICD-10 Finland
Acne vulgaris
105.7
307.7
3790
1394
L70.9
ICD-10 Finland
Acne, unspecified
20.9
307.7
495
261
D10AX03
ATC
azelaic acid; topical
6.0
307.7
1582
3560
S96
ICPC
Acne
6.3
302.1
542
941
D10AF01
ATC
clindamycin; topical
5.3
252.3
543
1113
70610
ICD-8 Finland
Diseases of sebaceous glands, Acne vulgaris
+∞
208.7
199
*
E0001A1, ,
ATC
5.5
193.6
394
764
E000001, ,
ATC
2.5
177.9
1493
7193
L73.8
ICD-10 Finland
Other specified follicular disorders
15.1
158.8
141
96
L71.9
ICD-10 Finland
Rosacea, unspecified
9.2
151.5
187
211
L71.8
ICD-10 Finland
Other rosacea
13.6
138.2
130
98
XQ848
NOMESCO Finland
Dermatological photography
6.8
133.1
211
319
L70.2
ICD-10 Finland
Acne varioliformis
18.0
125.0
101
57
D06BX01
ATC
metronidazole; topical
3.1
118.2
550
1924
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.0
93.9
1419
8318
C03DA01
ATC
spironolactone; oral
3.4
91.4
348
1074
L72.1
ICD-10 Finland
Trichilemmal cyst
3.6
90.2
306
876
7061A
ICD-9 Finland
Diseases of sebaceous glands, Other acne[ACNE VULGARIS]
+∞
83.5
80
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.0
71.2
339
1192
TQW80
NOMESCO Finland
Local dermatologic skincare
4.7
65.6
153
331
D10AD01
ATC
tretinoin; topical
4.3
62.7
165
393
N06AX11
ATC
mirtazapine; oral
1.7
55.2
1470
9933
J01FF01
ATC
clindamycin; systemic
1.8
54.7
1092
6816
S10
ICPC
Boil/carbuncle
2.6
51.1
317
1277
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
50.7
1004
6237
Z94.0
ICD-10 Finland
Kidney transplant status
6.0
49.9
88
148
H02AB06
ATC
prednisolone; systemic
1.6
47.7
1788
13030
L71.0
ICD-10 Finland
Perioral dermatitis
3.6
47.7
159
449
L04AA06
ATC
mycophenolic acid; systemic
4.2
45.5
122
295
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.2
45.5
93
180
J04BA02
ATC
dapsone; oral
10.5
45.4
50
48
L70.5
ICD-10 Finland
Acné excoriée
73.6
45.0
51
7
L73.9
ICD-10 Finland
Follicular disorder, unspecified
8.3
44.8
59
72
D07AC01
ATC
betamethasone; topical
1.6
44.2
1405
9816
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
43.7
867
5364
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.0
43.7
95
194
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.8
43.4
677
3901
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
6.8
42.3
66
98
J02AC01
ATC
fluconazole; systemic
1.5
42.2
1705
12549
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
2.7
41.9
235
899
N05BA04
ATC
oxazepam; oral
1.6
41.5
1099
7328
J01DB01
ATC
cefalexin; oral
1.6
41.4
4050
35882
L68.0
ICD-10 Finland
Hirsutism
8.2
41.0
54
66
L71
ICD-10 Finland
Rosacea
3.6
40.8
136
384
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
39.7
920
5923
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.5
39.6
251
1020
127
Kela drug reimbursment
Transplant complication
4.3
39.2
102
241
N03AX16
ATC
[U] pregabalin
1.8
39.2
687
4093
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
7.3
38.9
57
79
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
38.7
1348
9565
N05AH04
ATC
quetiapine; oral
1.6
38.3
1033
6904
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
38.2
1293
9112
TK800
NOMESCO Finland
Hemodialysis
4.5
38.1
92
205
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
6.7
37.7
60
91
137
Kela drug reimbursment
Uraemia requiring dialysis
6.7
37.7
60
91
N06AX16
ATC
venlafaxine; oral
1.7
37.7
773
4811
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
37.6
719
4389
A02BC02
ATC
pantoprazole; systemic
1.5
37.5
2366
18940
UJF32
NOMESCO Finland
Coloscopy
1.8
37.4
691
4176
L04AX01
ATC
azathioprine; systemic
2.5
37.3
242
995
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
2.7
36.2
204
783
380
Kela drug reimbursment
Adalimumab (hidradenitis suppurativa)
+∞
35.4
34
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
35.2
820
5271
N02AX02
ATC
tramadol; systemic, rectal
1.5
34.0
1298
9352
D07XC01
ATC
betamethasone; topical
2.0
34.0
400
2094
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
33.6
865
5693
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
33.4
507
2884
L04AD01
ATC
ciclosporin; systemic
3.7
33.4
108
299
N05CF01
ATC
zopiclone; oral
1.6
33.0
902
6022
L04AA01
ATC
[U] ciclosporin
5.2
33.0
67
129
L02.0
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of face
3.6
32.9
109
307
S29
ICPC
Skin symptom/complaint other
1.6
32.5
824
5400
J01AA02
ATC
doxycycline; systemic
1.4
31.9
2748
23016
B03XA02
ATC
darbepoetin alfa; parenteral
5.1
31.9
67
133
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
2.4
31.5
226
973
D05BB02
ATC
acitretin; oral
4.3
31.1
81
192
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
4.7
30.9
71
152
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
6.3
30.3
51
82
TQW99
NOMESCO Finland
Other minor procedure on skin
2.9
30.1
141
491
N03AX09
ATC
lamotrigine; oral
2.0
30.0
346
1796
196
Kela drug reimbursment
Paricalcitol and cinacalcet
9.5
29.7
35
37
70612
ICD-8 Finland
Diseases of sebaceous glands, Acne alia sive NUD
+∞
29.2
28
*
N05CD07
ATC
temazepam; oral
2.5
29.1
193
801
V03AE02
ATC
sevelamer; oral
9.3
29.1
35
38
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
28.9
766
5062
L21.0
ICD-10 Finland
Seborrhoea capitis
4.7
28.8
67
145
XQ800
NOMESCO Finland
Prick test
1.8
28.6
463
2682
A12AA04
ATC
calcium carbonate; oral
4.9
28.5
62
127
J01FA01
ATC
erythromycin; systemic
1.6
28.2
816
5502
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
5.1
27.9
58
114
D07AD01
ATC
clobetasol; topical
1.7
27.9
518
3120
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
27.7
672
4344
R06AE07
ATC
cetirizine; oral
1.4
27.4
2203
18046
N06AB04
ATC
citalopram; systemic
1.6
27.3
720
4747
B03XA01
ATC
erythropoietin; parenteral
8.8
27.1
34
39
L04AB04
ATC
adalimumab; parenteral
2.7
27.1
143
531
Z49.2
ICD-10 Finland
Other dialysis
6.3
26.9
45
72
B05DA
ATC
Isotonic solutions
6.0
26.7
47
79
N06AX21
ATC
duloxetine; oral
1.8
26.7
468
2773
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.1
26.5
55
108
J01MA02
ATC
ciprofloxacin; systemic
1.5
26.5
1153
8464
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
26.4
635
4093
L04AD02
ATC
tacrolimus; systemic
4.0
25.8
72
180
XQ802
NOMESCO Finland
Epicutan test
2.2
25.7
211
962
D07AB08
ATC
desonide; topical
1.7
25.5
516
3179
C03CA01
ATC
furosemide; systemic
1.9
25.4
361
2007
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
25.3
481
2913
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.4
25.1
176
750
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.8
25.0
431
2540
N02BE01
ATC
paracetamol; systemic, rectal
1.4
25.0
3854
34894
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
6.1
24.9
43
71
N18.8
ICD-10 Finland
Other chronic renal failure
4.4
24.9
62
142
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
24.9
389
2228
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.7
24.8
79
217
S97
ICPC
Chronic ulcer skin
2.7
24.7
130
482
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.1
24.5
244
1200
A02BC03
ATC
lansoprazole; oral
1.6
24.4
696
4666
B05DB
ATC
Hypertonic solutions
5.9
24.2
43
73
Z3231
NOMESCO Finland
Registered nurse
1.5
24.2
1051
7693
N03AX12
ATC
[U] gabapentin; oral
1.7
24.1
475
2906
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.9
24.0
111
384
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.5
24.0
899
6389
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.8
24.0
54
114
A11CC03
ATC
alfacalcidol; systemic
3.4
24.0
84
246
L91.0
ICD-10 Finland
Hypertrophic scar
3.0
23.8
105
354
V03AE01
ATC
polystyrene sulfonate; oral
5.8
23.6
43
75
N06AB03
ATC
fluoxetine; oral
1.6
23.6
533
3379
J04AB02
ATC
rifampicin; systemic
5.1
23.4
49
97
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.4
23.4
1114
8286
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
7.0
23.3
35
50
N06AX12
ATC
bupropion; oral
1.7
23.2
502
3147
P01AB01
ATC
metronidazole; oral, rectal
1.4
23.1
1502
11793
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
1.9
23.0
287
1530
C07AA05
ATC
propranolol; systemic
1.5
22.9
984
7175
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.4
22.8
1748
14087
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
22.8
1043
7698
L20.0
ICD-10 Finland
Besnier prurigo
1.6
22.8
604
3978
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
4.2
22.5
60
145
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.8
22.5
352
2015
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
3.2
22.5
91
292
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.3
22.4
177
795
A02BC05
ATC
esomeprazole; systemic
1.4
22.4
1243
9495
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
22.3
2178
18197
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
22.2
686
4677
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
22.1
173
773
D07AC13
ATC
mometasone; topical
1.4
22.0
1041
7723
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
21.9
214
1045
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
2.3
21.7
170
760
H3603, E103,
ICD-10 Finland
3.7
21.6
69
190
S21
ICPC
Skin texture symptom/complaint
1.6
21.6
563
3691
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
6.9
21.6
33
48
R4110
NOMESCO Finland
Physiotherapy
1.5
21.6
875
6305
WZC00
NOMESCO Finland
Treatment plan or consultation
1.4
21.5
1747
14170
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.1
21.5
91
300
L04AX03
ATC
methotrexate; systemic
1.8
21.3
345
1995
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
5.3
21.3
42
79
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.4
21.3
1564
12489
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
21.2
2295
19413
R06.0
ICD-10 Finland
Dyspnoea
1.5
21.2
800
5683
ZX120
NOMESCO Finland
Intravenous
1.9
21.1
287
1573
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
21.1
598
3995
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
21.1
1510
12004
M25.5
ICD-10 Finland
Pain in joint
1.4
21.0
1282
9929
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.9
21.0
62
162
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
20.9
1763
14365
Z71.8
ICD-10 Finland
Other specified counselling
1.4
20.9
1605
12894
B07.9
ICD-10 Finland
Verruca simplex
2.0
20.9
222
1120
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
1.9
20.7
254
1346
J01MA12
ATC
levofloxacin; systemic
1.7
20.7
440
2743
R53
ICD-10 Finland
Malaise and fatigue
1.4
20.7
1065
8013
E000008, ,
ATC
5.7
20.6
38
67
N06AB10
ATC
escitalopram; oral
1.4
20.6
1185
9087
N06AB06
ATC
sertraline; oral
1.5
20.6
648
4431
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.7
20.4
361
2141
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
1.9
20.2
246
1300
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
8.0
20.0
27
34
N05CF02
ATC
zolpidem; oral
1.5
19.9
579
3889
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.1
19.8
82
267
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.0
19.7
86
289
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
2.5
19.6
122
493
A02BC01
ATC
omeprazole; systemic
1.4
19.4
853
6228
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.1
19.4
179
856
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
19.4
304
1742
C07AB07
ATC
bisoprolol; oral
1.4
19.3
919
6810
N05AX08
ATC
risperidone; systemic
1.8
19.2
308
1777
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
1.8
19.2
288
1629
R03AC02
ATC
salbutamol; inhalant
1.3
19.1
2481
21405
V03AE03
ATC
lanthanum carbonate; oral
7.9
19.1
26
33
N18.0
ICD-10 Finland
End-stage renal disease
5.6
19.1
36
65
M79.6
ICD-10 Finland
Pain in limb
1.3
19.0
1596
12950
N05BA01
ATC
diazepam; systemic, rectal
1.7
19.0
407
2542
N06AB05
ATC
paroxetine; oral
1.9
18.9
240
1286
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
4.1
18.9
52
129
N06AX22
ATC
agomelatine; oral
2.2
18.9
158
727
A06AD11
ATC
lactulose; oral
1.8
18.9
312
1815
S18
ICPC
Laceration/cut
1.3
18.9
1533
12380
J01DA01
ATC
[U] cefalexin
1.3
18.8
2485
21469
N76.0
ICD-10 Finland
Acute vaginitis
1.6
18.8
510
3370
L72.0
ICD-10 Finland
Epidermal cyst
4.3
18.7
48
113
SPAT1301
SPAT
No procedures
1.4
18.6
1355
10756
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
7.7
18.6
26
34
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
18.6
245
1330
L01BA01
ATC
methotrexate; systemic
2.5
18.5
120
495
N05AX12
ATC
aripiprazole; systemic
1.7
18.4
317
1866
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
3.3
18.3
69
212
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
18.3
3900
35950
L30.3
ICD-10 Finland
Infective dermatitis
2.3
18.2
141
628
A10AB04
ATC
insulin lispro; parenteral
2.2
18.1
158
740
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
18.1
3803
34939
A10AB05
ATC
insulin aspart; parenteral
1.8
17.9
272
1544
ZYC06
NOMESCO Finland
Real-time text-based remote transaction
7.6
17.8
25
33
WZC30
NOMESCO Finland
Teaching
1.6
17.8
436
2814
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
17.7
667
4723
L02.8
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of other sites
2.6
17.7
100
386
Z3226
NOMESCO Finland
Physiotherapist
1.5
17.7
603
4186
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.7
17.5
32
56
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
6.3
17.5
29
46
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
17.5
327
1969
E000002, ,
ATC
1.5
17.4
611
4268
N06AX26
ATC
vortioxetine; oral
1.6
17.3
454
2975
A10AB01
ATC
insulin (human); parenteral
2.0
17.3
177
881
F45.8
ICD-10 Finland
Other somatoform disorders
1.6
17.2
444
2899
N05AH03
ATC
olanzapine; systemic
1.7
17.2
344
2110
L05.9
ICD-10 Finland
Pilonidal cyst without abscess
2.7
17.2
94
357
R50.9
ICD-10 Finland
Fever, unspecified
1.5
17.2
658
4674
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.4
17.0
784
5761
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.0
17.0
181
914
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
2.3
16.9
131
584
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
4.0
16.9
48
122
D06AX01
ATC
fusidic acid; topical
1.6
16.7
447
2942
M54.5
ICD-10 Finland
Low back pain
1.3
16.7
1488
12132
S04
ICPC
Lump/swelling localized
1.5
16.7
507
3434
R06AX27
ATC
desloratadine; oral
1.3
16.6
1552
12732
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
5.0
16.6
35
70
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
7.3
16.5
24
33
XCK10
NOMESCO Finland
Photography of fundus of eye
1.8
16.5
228
1258
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
16.4
3629
33268
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.1
16.4
163
803
N05BE01
ATC
buspirone; oral
2.3
16.4
119
517
D02AX
ATC
Other emollients and protectives
2.0
16.1
177
904
QBA10
NOMESCO Finland
Incision of skin of trunk
3.6
16.1
52
145
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
16.1
1667
13857
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
16.0
587
4131
H02AB09
ATC
hydrocortisone; systemic
2.3
16.0
118
516
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.7
15.9
268
1569
M79.1
ICD-10 Finland
Myalgia
1.4
15.8
648
4657
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.1
15.7
42
102
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
15.7
3102
27923
K65.0
ICD-10 Finland
Acute peritonitis
4.5
15.6
37
82
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
15.5
836
6305
Z49.0
ICD-10 Finland
Preparatory care for dialysis
4.8
15.4
34
71
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.3
15.2
116
515
KBV00
NOMESCO Finland
Insertion of stent into ureter
4.9
15.1
33
68
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
15.1
344
2180
D02AE01
ATC
carbamide; topical
1.7
15.0
251
1467
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
3.1
14.9
62
203
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
5.8
14.9
27
47
H02AB04
ATC
methylprednisolone; systemic
1.6
14.8
379
2468
WX002
NOMESCO Finland
Sedation and analgesia
1.5
14.8
486
3342
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
14.8
515
3586
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.4
14.7
623
4501
WW200
NOMESCO Finland
Immunization
2.2
14.7
119
541
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
14.7
660
4823
T36
ICD-10 Finland
Poisoning by systemic antibiotics
1.7
14.6
245
1431
D07CC01
ATC
betamethasone and antibiotics; topical
1.5
14.6
431
2897
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
1.9
14.6
181
964
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
14.6
176
930
H05BX01
ATC
cinacalcet; oral
6.3
14.5
24
38
K59.1
ICD-10 Finland
Functional diarrhoea
1.8
14.4
200
1104
N02BF02
ATC
pregabalin; oral
1.8
14.4
201
1112
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
2.2
14.4
125
585
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.8
14.4
208
1164
M03BX02
ATC
tizanidine; oral
1.3
14.4
2330
20386
N06AA09
ATC
amitriptyline; systemic
1.9
14.3
181
970
SFA10
NOMESCO Finland
One-surface restoration
1.3
14.3
2852
25553
K07.60
ICD-10 Finland
Snapping jaw
1.7
14.3
294
1815
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.5
14.3
550
3903
A07EC02
ATC
mesalazine; oral, rectal
1.8
14.3
229
1321
A07AA02
ATC
nystatin; oral
2.1
14.3
133
640
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
14.2
892
6884
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
14.2
314
1975
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.0
14.2
154
784
SPAT1260
SPAT
Consultation of another employee
1.4
14.1
711
5296
T89
ICPC
Diabetes insulin dependent
1.8
14.1
204
1142
SPAT1240
SPAT
Therapeutic discussion
1.4
14.1
763
5753
N03AG01
ATC
valproic acid; systemic, rectal
1.7
14.1
246
1455
NHQ40
NOMESCO Finland
Amputation of toe
5.1
14.1
29
57
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
14.0
365
2387
G44.2
ICD-10 Finland
Tension-type headache
1.4
14.0
620
4516
CKC15
NOMESCO Finland
Panretinal photocoagulation
4.7
13.9
32
69
N06AX03
ATC
mianserin; oral
2.2
13.8
118
549
A10AE05
ATC
insulin detemir; parenteral
1.8
13.8
197
1098
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
1.8
13.8
225
1305
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
13.7
3176
28887
ZXC50
NOMESCO Finland
Cryotherapy
3.3
13.7
51
156
A10AA02, ,
ATC
2.2
13.7
116
538
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
13.7
304
1914
A10AE04
ATC
insulin glargine; parenteral
1.7
13.6
259
1567
AA1AD
NOMESCO Finland
CT of head and brain
1.4
13.5
583
4225
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
13.4
1552
13012
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
2.8
13.4
66
238
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
13.4
1210
9830
UKC02
NOMESCO Finland
Cystoscopy
1.6
13.3
278
1724
E000007, ,
ATC
1.6
13.3
276
1709
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
13.3
1064
8501
SDA03
NOMESCO Finland
Periodontal treatment
1.3
13.2
1815
15523
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
13.2
599
4377
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
13.2
1239
10110
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.9
13.2
60
207
L23.0
ICD-10 Finland
Allergic contact dermatitis due to metals
3.2
13.2
50
155
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.6
13.2
274
1698
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
13.2
905
7074
A63.0
ICD-10 Finland
Anogenital (venereal) warts
1.6
13.1
285
1785
L65.9
ICD-10 Finland
Nonscarring hair loss, unspecified
5.1
13.1
27
53
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
13.1
161
856
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.8
13.1
66
241
F51.0
ICD-10 Finland
Nonorganic insomnia
1.4
13.1
825
6365
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
13.1
223
1311
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.9
13.0
61
214
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.0
13.0
140
711
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
5.9
13.0
23
39
H04AA01
ATC
glucagon; nasal, parenteral
1.9
13.0
169
915
A10AA01, ,
ATC
2.2
13.0
113
530
A02BA02
ATC
ranitidine; systemic
1.6
13.0
347
2283
R21
ICPC
Throat symptom/complaint
1.3
13.0
1651
13989
L60.0
ICD-10 Finland
Ingrowing nail
1.8
13.0
196
1112
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
1.7
12.9
266
1643
R42
ICD-10 Finland
Dizziness and giddiness
1.4
12.9
635
4708
K51.5
ICD-10 Finland
Left sided colitis
2.0
12.9
139
707
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
12.8
331
2160
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
1.5
12.8
410
2803
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
12.8
228
1356
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
12.7
698
5266
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
12.7
657
4908
SPAT1153
SPAT
Removal of sutures
1.3
12.7
858
6684
L01
ICPC
Neck symptom/complaint
1.4
12.7
681
5120
A46
ICD-10 Finland
Erysipelas
1.6
12.7
294
1871
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
12.6
2216
19457
N06AG02
ATC
moclobemide; oral
2.2
12.6
109
510
K50.9
ICD-10 Finland
Crohn disease, unspecified
2.5
12.6
79
322
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
12.6
677
5093
WQ031, ,
NOMESCO Finland
+∞
12.5
12
*
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.6
12.5
276
1737
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
12.5
669
5030
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.5
12.5
355
2369
N05AF03
ATC
chlorprothixene; systemic
2.2
12.4
107
500
L08.0
ICD-10 Finland
Pyoderma
3.1
12.4
51
166
SPAT1263
SPAT
Sampling
1.2
12.4
1974
17135
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
14.3
12.2
20
14
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
1.8
12.2
191
1095
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.7
12.2
228
1374
P29
ICPC
Psychological sympt/compl other
1.4
12.0
543
3967
N05AA02
ATC
levomepromazine; systemic
2.0
12.0
131
670
N30.0
ICD-10 Finland
Acute cystitis
1.4
12.0
663
5008
R51.80
ICD-10 Finland
Headache
1.3
12.0
817
6373
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.3
11.9
811
6323
N05AN01
ATC
lithium; oral
2.0
11.9
121
603
H00.00
ICD-10 Finland
Hordeolum
1.7
11.9
219
1315
J01FA06
ATC
roxithromycin; oral
1.3
11.9
1213
9986
S76
ICPC
Skin infection other
1.8
11.9
170
950
N06AA12
ATC
doxepin; systemic
2.2
11.9
100
464
F43.1
ICD-10 Finland
Post-traumatic stress disorder
1.7
11.9
212
1263
A05
ICPC
Feeling ill
1.4
11.8
580
4294
TLC02
NOMESCO Finland
Simple extraction of IUD
1.8
11.8
185
1061
A10AC01
ATC
insulin (human); parenteral
1.6
11.8
247
1533
N05AB03
ATC
perphenazine; systemic, rectal
2.0
11.8
122
612
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
1.9
11.8
140
737
H01.0
ICD-10 Finland
Blepharitis
1.6
11.7
305
1995
L05.0
ICD-10 Finland
Pilonidal cyst with abscess
2.5
11.7
74
303
ZXA00
NOMESCO Finland
Right side
1.4
11.6
574
4255
M01AE02
ATC
naproxen; oral, rectal
1.2
11.6
2698
24325
H02AB07
ATC
prednisone; oral
1.5
11.6
328
2185
CKD40
NOMESCO Finland
Endophotocoagulation of retina
3.4
11.6
40
117
Z30.0
ICD-10 Finland
General counselling and advice on contraception
1.4
11.6
536
3929
WX872
NOMESCO Finland
Intensive care
2.1
11.5
103
489
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
2.8
11.5
58
212
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
5.2
11.5
23
44
SPAT1310
SPAT
Counselling related to known health issue
1.3
11.5
1486
12576
F29
ICD-10 Finland
Unspecified nonorganic psychosis
1.7
11.5
228
1397
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
11.5
1199
9893
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.2
11.4
44
138
W78
ICPC
Pregnancy
0.8
11.4
921
11347
Z2446
NOMESCO Finland
Social worker
1.5
11.4
310
2047
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.8
11.4
55
197
ZYC01
NOMESCO Finland
Remote contact by phone
1.6
11.3
271
1741
N06AB08
ATC
fluvoxamine; oral
2.4
11.2
72
297
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
11.2
373
2572
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
1.9
11.2
148
807
G43.9
ICD-10 Finland
Migraine, unspecified
1.5
11.2
397
2772
E000006, ,
ATC
1.6
11.2
232
1438
H13
ICPC
Plugged feeling ear
1.4
11.2
511
3738
A07AA09
ATC
vancomycin; oral
3.2
11.2
42
130
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
11.2
291
1905
K02.1
ICD-10 Finland
Caries of dentine
1.2
11.1
3163
29057
K50.8
ICD-10 Finland
Other Crohn disease
2.3
11.1
82
360
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
2.7
11.1
56
205
L03
ICPC
Low back symptom/complaint
1.3
11.1
1181
9759
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
11.1
645
4906
ZXA05
NOMESCO Finland
Left side
1.4
11.1
531
3917
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
11.0
2418
21620
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.3
11.0
730
5662
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.6
11.0
263
1686
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
1.9
11.0
133
704
K03.64
ICD-10 Finland
Dental calculus supragingival
1.2
11.0
1813
15737
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
2.7
11.0
56
206
R52.9
ICD-10 Finland
Pain, unspecified
1.5
11.0
343
2333
J01DA09
ATC
[U] cefadroxil
1.3
11.0
979
7913
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
5.7
11.0
20
35
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
2.9
11.0
49
168
R11
ICD-10 Finland
Nausea and vomiting
1.5
10.9
398
2792
R55
ICD-10 Finland
Syncope and collapse
1.6
10.9
289
1897
L73.0
ICD-10 Finland
Acne keloid
43.3
10.9
13
*
J01FA10
ATC
azithromycin; systemic
1.2
10.9
3034
27784
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.7
10.8
201
1210
N05BA12
ATC
alprazolam; oral
1.6
10.8
273
1773
Z01.9
ICD-10 Finland
Special examination, unspecified
1.7
10.8
183
1074
G04BD04
ATC
oxybutynin; oral, transdermal
2.0
10.8
115
583
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.4
10.8
425
3026
P01
ICPC
Feeling anxious/nervous/tense
1.3
10.8
1117
9198
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.8
10.8
153
854
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.0
10.7
46
154
SPAT1379
SPAT
Health check-up of pregnant person
0.7
10.7
635
8173
QDH05
NOMESCO Finland
Correction of deformity of toe nail
8.8
10.7
22
25
L23.2
ICD-10 Finland
Allergic contact dermatitis due to cosmetics
2.9
10.7
50
176
L90.6
ICD-10 Finland
Striae atrophicae
4.6
10.7
25
55
J01EA01
ATC
trimethoprim; systemic
1.3
10.6
886
7094
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
1.8
10.6
143
785
ZXA10
NOMESCO Finland
Bilateral
1.4
10.6
507
3736
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.5
10.6
357
2468
R06AE09
ATC
levocetirizine; oral
1.3
10.6
684
5286
A10AD01
ATC
insulin (human); parenteral
2.4
10.6
73
312
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.5
10.5
308
2067
Z01.2
ICD-10 Finland
Dental examination
1.2
10.5
2396
21468
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.0
10.5
109
548
C08CA01
ATC
amlodipine; oral
1.4
10.5
518
3838
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
5.0
10.5
22
44
TK820
NOMESCO Finland
Peritoneal dialysis
4.8
10.4
23
48
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
10.4
1231
10287
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.3
10.4
840
6694
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.4
10.4
456
3309
205
Kela drug reimbursment
Chronic hypertension
1.6
10.4
256
1654
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
2.6
10.4
58
224
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
2.3
10.4
79
352
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.5
10.4
344
2371
D01
ICPC
Abdominal pain/cramps general
1.3
10.3
694
5392
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.5
10.3
275
1810
N03AE01
ATC
clonazepam; systemic
1.8
10.2
156
889
ZY010
NOMESCO Finland
Hospital outpatient
1.5
10.2
328
2244
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
0.7
10.2
284
4165
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
10.2
193
1169
SPAT1380
SPAT
Postpartum check-up
0.7
10.2
503
6655
R60.9
ICD-10 Finland
Oedema, unspecified
1.9
10.0
121
641
WX402
NOMESCO Finland
General anaesthesia
1.3
10.0
762
6022
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
10.0
152
866
SDA01
NOMESCO Finland
Periodontal treatment, very brief
1.2
10.0
1583
13653
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
4.6
10.0
23
50
H05BX02
ATC
paricalcitol; systemic
40.1
10.0
12
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.7
10.0
195
1192
L50.3
ICD-10 Finland
Dermatographic urticaria
2.1
9.9
89
424
R00.0
ICD-10 Finland
Tachycardia, unspecified
1.7
9.9
173
1025
L04AB06
ATC
golimumab; parenteral
2.7
9.9
50
184
C09AA02
ATC
enalapril; systemic
1.6
9.9
258
1691
N19
ICD-10 Finland
Unspecified kidney failure
2.9
9.9
46
162
L63.8
ICD-10 Finland
Other alopecia areata
12.2
9.8
17
14
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
9.8
859
6916
C09CA06
ATC
candesartan; oral
1.4
9.8
572
4350
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.5
9.8
272
1806
WX290
NOMESCO Finland
Other blockage of nerve
1.2
9.8
2711
24682
L84
ICD-10 Finland
Corns and callosities
2.1
9.8
94
460
M05BA04
ATC
alendronic acid; oral
2.2
9.8
78
355
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
1.7
9.7
167
985
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
0.8
9.7
1055
12582
X58
ICD-10 Finland
Exposure to other specified factors
1.3
9.7
636
4920
K30
ICD-10 Finland
Functional dyspepsia
1.4
9.7
384
2736
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
3.8
9.7
29
77
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
2.5
9.7
60
244
R02
ICPC
Shortness of breath/dyspnoea
1.4
9.7
423
3068
N02BF01
ATC
gabapentin; oral
1.6
9.7
218
1381
SAA04
NOMESCO Finland
Special examination of mouth
1.5
9.6
326
2255
J01MA14
ATC
moxifloxacin; systemic
1.6
9.6
204
1272
F41.1
ICD-10 Finland
Generalized anxiety disorder
1.4
9.6
408
2945
XQ845
NOMESCO Finland
Dermatoscopy
3.0
9.6
40
132
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.5
9.6
342
2390
N02AA05
ATC
oxycodone; systemic
1.5
9.6
254
1669
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
1.8
9.6
132
730
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
1.8
9.6
132
730
G43.3
ICD-10 Finland
Complicated migraine
1.9
9.6
108
560
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
9.6
3435
32032
F90.0
ICD-10 Finland
Disturbance of activity and attention
1.4
9.6
378
2694
RS221, ,
NOMESCO Finland
2.5
9.5
59
240
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.6
9.5
206
1291
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
1.9
9.5
124
674
D10AE01
ATC
benzoyl peroxide; topical
15.0
9.5
15
10
D07AA02
ATC
hydrocortisone; topical
1.3
9.5
724
5725
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.4
9.5
433
3167
F60.9
ICD-10 Finland
Personality disorder, unspecified
2.2
9.4
79
367
UJH02
NOMESCO Finland
Anoscopy
2.0
9.4
95
474
F34.1
ICD-10 Finland
Dysthymia
1.7
9.4
179
1087
EMB10
NOMESCO Finland
Tonsillectomy
1.4
9.4
432
3164
KMAK, ,
NOMESCO Finland
1.2
9.4
2298
20651
MA3AE
NOMESCO Finland
Combined first trimester screening
0.7
9.4
282
4069
L17
ICPC
Foot/toe symptom/complaint
1.3
9.3
1081
8998
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
21.7
9.3
13
6
QBE05
NOMESCO Finland
Excision of sweat glands or sweat gland bearing skin from trunk
21.7
9.3
13
6
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
9.3
1377
11774
H29
ICPC
Ear symptom/complaint other
1.4
9.3
355
2514
A07EA06
ATC
budesonide; oral, local oral
1.8
9.3
147
848
W90
ICPC
Uncompl labour/delivery livebirth
0.6
9.3
206
3168
D19
ICPC
Teeth/gum symptom/complaint
1.2
9.3
1399
11984
R01AD58
ATC
fluticasone, combinations; nasal
1.2
9.3
1241
10497
WZC00, ,
SPAT
1.4
9.3
530
4019
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
10.6
9.3
17
16
TPH07
NOMESCO Finland
Cathetrisation of artery
1.6
9.2
212
1349
SPAT1307
SPAT
Psychosocial counselling and guidance
1.3
9.2
590
4550
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.7
9.2
155
911
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.4
9.2
399
2893
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.1
9.2
85
411
R05
ICPC
Cough
1.3
9.1
1038
8619
SPAT1146
SPAT
Puncture of abscess or incision of skin
2.5
9.1
57
233
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.0
9.1
97
493
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.5
9.1
267
1794
N06BA04
ATC
methylphenidate; oral
1.5
9.1
331
2322
H10
ICD-10 Finland
Conjunctivitis
1.4
9.1
387
2794
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
9.1
322
2248
XKD00
NOMESCO Finland
Uroflowmetry
1.6
9.1
221
1425
SFA20
NOMESCO Finland
Two-surface restoration
1.2
9.1
2742
25085
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
9.1
262
1755
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
9.1
178
1090
J45.1
ICD-10 Finland
Nonallergic asthma
1.5
9.1
259
1732
R04.0
ICD-10 Finland
Epistaxis
1.7
9.0
160
953
C10AA05
ATC
atorvastatin; oral
1.3
9.0
558
4280
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
9.0
198
1246
QXA70, ,
SPAT
1.7
9.0
143
826
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.8
9.0
119
651
A07EC01
ATC
sulfasalazine; oral, rectal
1.5
9.0
239
1573
A29
ICPC
General symptom/complaint other
1.4
9.0
383
2767
K03.00
ICD-10 Finland
Approximal wear
1.5
9.0
295
2030
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.8
9.0
944
11314
T78.4
ICD-10 Finland
Allergy, unspecified
1.5
9.0
242
1598
EBA10
NOMESCO Finland
Operative extraction of tooth
1.3
8.9
1018
8455
ZXE00
NOMESCO Finland
One hour or less
1.2
8.9
1429
12308
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
1.9
8.9
106
560
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
8.9
1832
16167
XF404
NOMESCO Finland
Ambulatory ECG
1.6
8.9
198
1250
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
1.7
8.9
166
1003
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.5
8.9
273
1853
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.4
8.9
438
3244
JAL21
NOMESCO Finland
Laparoscopic excision or destruction of lesion of peritoneum
2.1
8.9
77
363
A28
ICPC
Limited function/disability NOS
1.6
8.8
201
1277
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
8.7
202
1288
P76
ICPC
Depressive disorder
1.4
8.7
410
3012
ZXE30
NOMESCO Finland
More than five and less than seven hours
1.8
8.7
123
687
R01AD09
ATC
mometasone; nasal
1.2
8.7
2004
17862
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
2.1
8.7
80
386
A06AC51
ATC
ispaghula, combinations; oral
1.8
8.7
122
680
Z50.1
ICD-10 Finland
Other physical therapy
1.8
8.7
118
651
N03AX11
ATC
topiramate; oral
1.8
8.7
122
681
Z00.0
ICD-10 Finland
General medical examination
1.3
8.6
823
6689
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
8.6
937
7734
-1, ,
NOMESCO Finland
1.2
8.6
1963
17474
R03BA02
ATC
budesonide; inhalant
1.3
8.6
678
5379
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
2.6
8.6
48
186
R61.0
ICD-10 Finland
Localized hyperhidrosis
3.0
8.6
37
125
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
3.9
8.6
24
61
ZXD10
NOMESCO Finland
Scheduled procedure
1.2
8.6
1137
9598
Z3229
NOMESCO Finland
Other healthcare associate professional
1.5
8.6
230
1518
CKC12
NOMESCO Finland
Photocoagulation of retina
1.9
8.5
95
491
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.3
8.5
59
253
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
8.5
203
1303
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
1.6
8.5
174
1076
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
8.5
474
3578
L82
ICD-10 Finland
Seborrhoeic keratosis
1.4
8.5
322
2277
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.7
8.5
146
863
A07EA02
ATC
hydrocortisone; rectal
2.1
8.5
73
343
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
8.5
550
4247
XKC03
NOMESCO Finland
Water cystometry
2.3
8.5
60
260
ZYC01, ,
SPAT
1.3
8.5
632
4979
L04AC05
ATC
ustekinumab; parenteral
3.2
8.4
32
100
F31.8
ICD-10 Finland
Other bipolar affective disorders
1.8
8.4
117
650
A04AA01
ATC
ondansetron; systemic, rectal
1.6
8.4
203
1307
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
8.4
472
3567
Z94.4
ICD-10 Finland
Liver transplant status
4.2
8.4
22
53
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
8.4
331
2358
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
2.6
8.4
45
171
K50.1
ICD-10 Finland
Crohn disease of large intestine
2.4
8.3
55
231
A10AA03, ,
ATC
2.9
8.3
37
127
7061X
ICD-9 Finland
Diseases of sebaceous glands, Other acne[ACNE ALIA DEFINITA]
+∞
8.3
8
*
WYA10
NOMESCO Finland
Emergency care or similar visit
1.4
8.3
362
2625
R06AX22
ATC
ebastine; oral
1.3
8.3
618
4865
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
3.7
8.3
25
67
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.4
8.3
335
2398
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
2.0
8.3
87
441
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.4
8.3
55
232
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
0.8
8.3
782
9501
M79.7
ICD-10 Finland
Fibromyalgia
1.8
8.3
122
691
CKC10
NOMESCO Finland
Local photocoagulation of retina
3.0
8.2
34
112
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.7
8.2
151
909
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.3
8.2
651
5167
3007
Kela drug reimbursment
Erenumab and fremanezumab
2.1
8.2
78
381
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
0.8
8.2
635
7903
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.4
8.2
355
2574
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.7
8.2
154
934
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
8.2
660
5254
N04BC05
ATC
pramipexole; oral
1.7
8.2
132
768
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.4
8.1
302
2128
D06BB04
ATC
podophyllotoxin; topical
1.5
8.1
290
2028
N06BA12
ATC
lisdexamfetamine; oral
1.9
8.1
99
528
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
0.8
8.1
606
7582
C07AB02
ATC
metoprolol; systemic
1.5
8.1
284
1979
F41.09
ICD-10 Finland
UNS Panic Syndrome
1.6
8.1
195
1256
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
4.5
8.1
19
42
EBA00
NOMESCO Finland
Extraction of tooth
1.2
8.1
1841
16362
I70.0
ICD-10 Finland
Atherosclerosis of aorta
33.3
8.1
10
*
A10AE06
ATC
insulin degludec; parenteral
1.7
8.0
131
764
B01AC04
ATC
clopidogrel; oral
1.7
8.0
148
893
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.4
8.0
328
2354
D20
ICPC
Mouth/tongue/lip symptom/complaint
1.6
8.0
189
1212
R00.2
ICD-10 Finland
Palpitations
1.4
8.0
314
2237
XCK00
NOMESCO Finland
Perimetry
1.8
8.0
118
669
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
1.9
8.0
102
553
H00.1
ICD-10 Finland
Chalazion
1.7
8.0
142
849
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.2
7.9
1229
10528
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
3.8
7.9
23
60
SFA30
NOMESCO Finland
Three-surface restoration
1.2
7.9
1380
11961
XCD20
NOMESCO Finland
Photoangiography of eye
3.3
7.9
28
84
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.5
7.9
225
1505
D07BC01
ATC
betamethasone and antiseptics; topical
1.4
7.9
306
2175
E87.5
ICD-10 Finland
Hyperkalaemia
3.7
7.9
24
65
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
13.0
7.9
13
10
W85
ICPC
Gestational diabetes
0.6
7.9
150
2385
TAB00
NOMESCO Finland
Lumbar puncture
1.6
7.8
167
1045
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
1.7
7.8
126
732
R60.0
ICD-10 Finland
Localized oedema
1.5
7.8
242
1647
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.2
7.8
60
270
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
7.8
148
900
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
2.7
7.8
40
149
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.3
7.8
56
245
B01AA03
ATC
warfarin; systemic
1.6
7.8
186
1197
R4120
NOMESCO Finland
Occupational therapy
1.6
7.8
187
1205
P01BA02
ATC
hydroxychloroquine; oral
1.5
7.8
207
1365
OAA12, ,
SPAT
0.6
7.8
187
2822
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
1.9
7.7
89
466
G47.3
ICD-10 Finland
Sleep apnoea
1.3
7.7
531
4134
L21
ICD-10 Finland
Seborrhoeic dermatitis
2.0
7.7
75
370
N06AX05
ATC
trazodone; oral
1.9
7.7
95
509
ZZA00
NOMESCO Finland
Split skin graft
2.4
7.7
51
215
H36.01
ICD-10 Finland
Diabetic maculopathy
2.6
7.7
44
173
JL9AE
NOMESCO Finland
Ultrasound examination of pancreas transplant
15.0
7.7
12
8
K59.0
ICD-10 Finland
Constipation
1.6
7.7
169
1066
H3601, E103,
ICD-10 Finland
2.5
7.7
47
191
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
7.7
369
2722
R35
ICD-10 Finland
Polyuria
1.7
7.7
139
835
H3600, E103,
ICD-10 Finland
2.2
7.7
62
285
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
3.5
7.7
25
71
L28.1
ICD-10 Finland
Prurigo nodularis
4.3
7.7
19
44
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
5.9
7.7
20
34
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.4
7.7
354
2595
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
7.4
7.6
17
23
M54.4
ICD-10 Finland
Lumbago with sciatica
1.3
7.6
554
4345
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.1
7.6
73
358
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.7
7.6
129
760
H26.2
ICD-10 Finland
Complicated cataract
3.1
7.6
30
96
H03AA01
ATC
levothyroxine sodium; systemic
1.3
7.6
646
5170
OAA11, ,
SPAT
0.7
7.6
311
4253
N94.5
ICD-10 Finland
Secondary dysmenorrhoea
1.8
7.6
117
671
J35.0
ICD-10 Finland
Chronic tonsillitis
1.4
7.6
360
2648
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.0
7.6
33
112
C01CA24
ATC
epinephrine; parenteral
1.4
7.6
310
2224
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.2
7.6
63
293
JN3AD
NOMESCO Finland
Abdominal CT examination
1.4
7.6
271
1898
XPX08
NOMESCO Finland
Intraoperative flow measurement
6.7
7.6
18
27
L71.1
ICD-10 Finland
Rhinophyma
25.0
7.6
10
*
P06
ICPC
Sleep disturbance
1.3
7.6
542
4245
XF402
NOMESCO Finland
ECG with work load test
1.6
7.5
166
1048
D11AH01
ATC
tacrolimus; topical
2.1
7.5
67
320
SPAT1262
SPAT
Handing over of treatment supplies
1.4
7.5
385
2869
SPAT1312
SPAT
General health counselling
1.2
7.5
1716
15230
L04AB05
ATC
certolizumab pegol; parenteral
2.9
7.5
33
113
X23
ICPC
Fear sexually transm dis female
1.3
7.5
535
4187
K08.80
ICD-10 Finland
Toothache NOS
1.4
7.5
390
2915
H81
ICPC
Excessive ear wax
1.4
7.5
357
2631
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.3
7.5
54
237
A01
ICPC
Pain general/multiple sites
1.4
7.5
283
2004
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
7.4
469
3607
E000003, ,
ATC
1.6
7.4
167
1059
L13.0
ICD-10 Finland
Dermatitis herpetiformis
4.2
7.4
19
45
R06.5
ICD-10 Finland
Mouth breathing
1.4
7.4
275
1938
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.6
7.4
154
958
F33.1
ICD-10 Finland
Recurrent depressive disorder, current episode moderate
1.5
7.4
193
1266
D07AB01
ATC
clobetasone; topical
1.8
7.4
97
530
P74
ICPC
Anxiety disorder/anxiety state
1.4
7.4
318
2301
C02AC05
ATC
moxonidine; oral
2.2
7.4
57
257
D09AB01
ATC
zinc bandage without supplements; topical
2.4
7.4
50
213
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
3.1
7.4
30
98
XA402
NOMESCO Finland
ENMG
2.2
7.4
59
270
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.9
7.4
90
481
M01CB01
ATC
sodium aurothiomalate; parenteral
3.5
7.4
24
68
L92.1
ICD-10 Finland
Necrobiosis lipoidica, not elsewhere classified
6.4
7.4
18
28
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
1.5
7.4
222
1504
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
7.3
455
3493
L70.3
ICD-10 Finland
Acne tropica
+∞
7.3
7
*
J01CA08
ATC
pivmecillinam; oral
1.2
7.3
1622
14356
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
2.2
7.3
59
272
TKC20
NOMESCO Finland
Catheterisation of bladder
1.7
7.3
121
711
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.4
7.3
365
2713
J05AB11
ATC
valaciclovir; oral
1.3
7.2
440
3366
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.3
7.2
427
3253
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
3.2
7.2
28
89
R01AD08
ATC
fluticasone; nasal
1.2
7.2
1114
9530
A01AB04
ATC
amphotericin B; local oral
2.1
7.2
61
286
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
2.0
7.2
72
360
WZC30, ,
SPAT
1.7
7.2
134
812
S01
ICPC
Pain/tenderness of skin
1.6
7.2
158
998
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.8
7.2
106
602
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
2.3
7.2
49
210
N02CD01
ATC
erenumab; parenteral
2.2
7.2
55
248
J34.3
ICD-10 Finland
Hypertrophy of nasal turbinates
1.9
7.1
85
451
R52.2
ICD-10 Finland
Other chronic pain
1.8
7.1
109
626
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
7.1
201
1344
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
2.8
7.1
33
117
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.4
7.1
312
2270
UJF92
NOMESCO Finland
Capsular endoscopy
1.9
7.1
87
467
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
6.0
7.0
18
30
K50.0
ICD-10 Finland
Crohn disease of small intestine
2.0
7.0
71
356
H57.1
ICD-10 Finland
Ocular pain
1.6
7.0
161
1027
N05AA01
ATC
chlorpromazine; systemic, rectal
2.8
7.0
34
123
R33
ICD-10 Finland
Retention of urine
1.8
7.0
106
606
D05AX02
ATC
calcipotriol; topical
2.0
7.0
74
377
A03FA02
ATC
cisapride; oral, rectal
1.6
7.0
158
1004
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.0
7.0
76
391
SPAT1229
SPAT
Assessment of need for aid
1.7
7.0
114
666
Z91.5
ICD-10 Finland
Personal history of self-harm
3.1
7.0
28
91
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.6
7.0
148
927
A02BA03
ATC
famotidine; systemic
2.5
7.0
42
170
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.4
7.0
380
2862
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
3.9
7.0
20
52
331
Kela drug reimbursment
Atomoxetine, dexamphetamine, guanfacine and lisdexamphetamine
1.8
7.0
104
593
E10
ICD-10 Finland
Type 1 diabetes mellitus
1.8
6.9
101
571
K80
ICPC
Cardiac arrhythmia NOS
1.5
6.9
183
1205
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.6
6.9
175
1141
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
3.4
6.9
24
71
TQX05
NOMESCO Finland
Skin puncture, unspecified location
4.4
6.9
17
39
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
6.9
87
470
K10.3
ICD-10 Finland
Alveolitis of jaws
1.5
6.9
231
1597
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.9
2496
22951
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
2.2
6.9
58
271
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
6.9
79
414
SCA01
NOMESCO Finland
Preventive oral health care, short
1.2
6.9
1959
17675
ZQX00
NOMESCO Finland
0-4% of the skin
7.5
6.9
15
20
H70
ICPC
Otitis externa
1.9
6.9
85
457
R20.2
ICD-10 Finland
Paraesthesia of skin
1.4
6.9
262
1858
C08CA02
ATC
felodipine; oral
1.8
6.9
94
522
R4180
NOMESCO Finland
Podiatric therapy
2.9
6.9
31
108
D11AH02
ATC
pimecrolimus; topical
2.7
6.9
36
136
WZB00, ,
SPAT
1.2
6.8
742
6114
N05AD01
ATC
haloperidol; systemic
2.0
6.8
69
346
WX892
NOMESCO Finland
Monitored bed care
1.5
6.8
177
1162
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.8
6.8
96
538
G04CA02
ATC
tamsulosin; oral
1.4
6.8
254
1795
TK810
NOMESCO Finland
Hemofiltration
4.1
6.8
18
44
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.4
6.8
298
2167
S92
ICPC
Sweat gland disease
10.9
6.8
12
11
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.3
6.8
391
2971
I79.2*E11.5
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
39.9
6.7
8
*
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
6.7
566
4524
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
0.7
6.7
374
4876
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
6.7
352
2633
D05AX52
ATC
calcipotriol, combinations; topical
1.6
6.7
132
811
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
4.3
6.7
17
40
ZX112
NOMESCO Finland
Subcutaneous
2.2
6.7
51
229
H10.5
ICD-10 Finland
Blepharoconjunctivitis
1.9
6.7
75
390
KH1AD
NOMESCO Finland
CT of urinary organs
1.8
6.7
91
504
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
1.7
6.7
128
781
S06
ICPC
Rash localized
1.5
6.7
201
1361
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.6
6.7
144
905
R83
ICPC
Respiratory infection other
1.2
6.7
1628
14493
WX730
NOMESCO Finland
Conventional respirator
2.6
6.7
36
138
F41.8
ICD-10 Finland
Other specified anxiety disorders
1.5
6.7
219
1510
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.6
6.7
135
836
R03DC03
ATC
montelukast; oral
1.3
6.7
620
5018
N94.1
ICD-10 Finland
Dyspareunia
1.7
6.7
111
653
RJ425, ,
NOMESCO Finland
22.5
6.7
9
*
SPAT1197
SPAT
Extensive health check-up of expecting family
0.8
6.7
761
9076
IGY02, ,
SPAT
2.0
6.6
68
343
B34.9
ICD-10 Finland
Viral infection, unspecified
1.5
6.6
177
1169
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
1.8
6.6
98
557
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
1.9
6.6
81
434
K02.0
ICD-10 Finland
Caries limited to enamel
1.2
6.6
1232
10713
J05AB01
ATC
aciclovir; systemic
1.2
6.6
706
5805
K11.5
ICD-10 Finland
Sialolithiasis
2.3
6.6
46
199
K03.0
ICD-10 Finland
Excessive attrition of teeth
1.7
6.6
108
632
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
1.6
6.6
142
893
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.4
6.6
335
2495
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
2.9
6.6
30
105
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.6
6.6
161
1043
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
7.8
6.6
14
18
X15
ICPC
Vaginal symptom/complaint other
1.4
6.6
259
1848
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.3
6.6
433
3352
JLE70
NOMESCO Finland
Inspection and preparation of pancreas, pre-transplantation
12.2
6.6
11
9
A12AA12
ATC
[U] calcium acetate
12.2
6.6
11
9
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.3
6.6
483
3796
C10AX09
ATC
ezetimibe; oral
1.5
6.6
203
1384
ZZR00
NOMESCO Finland
Flap of skin
2.8
6.5
31
111
G93.3
ICD-10 Finland
Postviral fatigue syndrome
2.7
6.5
34
128
J30.3
ICD-10 Finland
Other allergic rhinitis
1.5
6.5
178
1182
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
3.2
6.5
24
74
L40.8
ICD-10 Finland
Other psoriasis
3.3
6.5
23
69
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
10.0
6.5
12
12
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
2.6
6.5
35
134
Z02.7
ICD-10 Finland
Issue of medical certificate
1.4
6.5
259
1852
K51.8
ICD-10 Finland
Other ulcerative colitis
2.1
6.5
59
285
R51
ICD-10 Finland
Headache
1.4
6.5
281
2041
SPAT1255
SPAT
Intravenous administration of medicine
1.6
6.4
154
993
F43.29
ICD-10 Finland
Adaptation disorder UNS
1.7
6.4
117
705
Z99.2
ICD-10 Finland
Dependence on renal dialysis
6.2
6.4
16
26
E66.8
ICD-10 Finland
Other obesity
1.5
6.4
195
1324
S01GX08
ATC
ketotifen; ophthalmic
1.5
6.4
199
1357
F43.21
ICD-10 Finland
Adaptation disorder with prolonged depression
2.4
6.4
42
177
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.4
6.4
274
1984
Z71.9
ICD-10 Finland
Counselling, unspecified
1.4
6.4
258
1849
F40.9
ICD-10 Finland
Phobic anxiety disorder, unspecified
2.5
6.4
39
159
K61.0
ICD-10 Finland
Anal abscess
1.9
6.4
71
369
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
14.3
6.4
10
7
ZXC07
NOMESCO Finland
Carbon dioxide laser
14.3
6.4
10
7
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
2.7
6.4
33
124
D11
ICPC
Diarrhoea
1.3
6.4
622
5063
B35.3
ICD-10 Finland
Tinea pedis
1.6
6.4
158
1028
D06BB10
ATC
imiquimod; topical
1.5
6.4
179
1197
H53.1
ICD-10 Finland
Subjective visual disturbances
1.5
6.3
210
1451
188
Kela drug reimbursment
Psychosis requiring demanding treatment
2.7
6.3
31
113
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.0
6.3
62
308
L05
ICPC
Flank/axilla symptom/complaint
1.5
6.3
188
1271
N76.4
ICD-10 Finland
Abscess of vulva
2.6
6.3
35
136
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
6.3
94
536
H40.0
ICD-10 Finland
Glaucoma suspect
1.7
6.3
117
709
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
2.2
6.3
48
216
Z37.0
ICD-10 Finland
Single live birth
0.7
6.3
323
4260
L50.9
ICD-10 Finland
Urticaria, unspecified
1.5
6.3
183
1232
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
1.9
6.3
69
357
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
1.9
6.3
72
378
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
1.5
6.3
211
1462
R01AD12
ATC
fluticasone furoate; nasal
1.2
6.3
1544
13741
N07BB01
ATC
disulfiram; oral
1.6
6.3
134
842
J01CA04
ATC
amoxicillin; systemic
1.2
6.3
4242
40894
F13.29
ICD-10 Finland
Addiction caused by sedative and hypnotic UNS
3.4
6.3
21
61
QAE50
NOMESCO Finland
Dermabrasion of superficial lesion of skin of head or neck
18.0
6.3
9
5
R19.5
ICD-10 Finland
Other faecal abnormalities
2.2
6.2
48
217
319
Kela drug reimbursment
Adalimumab, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, sekukinumab and ustekinumab (skin psoriasis)
3.2
6.2
23
71
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.3
6.2
498
3955
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.3
6.2
428
3332
70600
ICD-8 Finland
Diseases of sebaceous glands, Acne necrotica
+∞
6.2
6
*
7062A
ICD-9 Finland
Diseases of sebaceous glands, Sebaceous cyst[CYSTA SEBACEA (ATHEROMA)]
+∞
6.2
6
*
7061E
ICD-9 Finland
Diseases of sebaceous glands, Other acne[ACNE CONGLOBATA]
+∞
6.2
6
*
C05AA08
ATC
fluocortolone; rectal, topical
1.4
6.2
261
1883
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
1.4
6.2
244
1740
L03.3
ICD-10 Finland
Cellulitis of trunk
2.8
6.2
29
103
SPAT1254
SPAT
Administration of medicine
1.2
6.2
674
5552
C10AA01
ATC
simvastatin; oral
1.3
6.2
397
3061
M03AX01
ATC
botulinum toxin; parenteral
1.9
6.2
72
380
Z2221
NOMESCO Finland
Medical doctor
1.2
6.2
975
8343
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
2.3
6.2
45
199
L01.1
ICD-10 Finland
Impetiginization of other dermatoses
2.6
6.2
34
132
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.1
6.2
53
251
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
1.7
6.1
95
548
F48.0
ICD-10 Finland
Neurasthenia
6.3
6.1
15
24
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
6.3
6.1
15
24
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
2.1
6.1
57
278
WX307
NOMESCO Finland
Obstetric epidural analgesia
0.8
6.1
446
5607
F50.9
ICD-10 Finland
Eating disorder, unspecified
1.7
6.1
102
601
F32
ICD-10 Finland
Depressive episode
1.4
6.1
297
2197
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
2.7
6.1
32
121
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.3
6.1
473
3742
PE1AT
NOMESCO Finland
Femoral artery PTA
7.7
6.1
13
17
R74
ICPC
Upper respiratory infection acute
1.2
6.1
2024
18432
CBB00
NOMESCO Finland
Excision of chalazion
2.3
6.1
44
194
R4190
NOMESCO Finland
Nutritional therapy
1.5
6.1
154
1007
J96.1
ICD-10 Finland
Chronic respiratory failure
3.0
6.1
26
88
N94.4
ICD-10 Finland
Primary dysmenorrhoea
1.5
6.1
191
1307
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
0.7
6.1
217
3033
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.3
6.1
339
2563
L04AB02
ATC
infliximab; parenteral
2.5
6.1
37
151
H3603, E113,
ICD-10 Finland
4.1
6.1
16
39
MAX99
NOMESCO Finland
Assistance to normal delivery
0.8
6.0
420
5312
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
1.3
6.0
431
3374
QDH01
NOMESCO Finland
Excision of nail bed in toe
8.6
6.0
12
14
N05AE04
ATC
ziprasidone; systemic
2.3
6.0
41
176
N02CC06
ATC
eletriptan; oral
1.5
6.0
170
1138
F33
ICD-10 Finland
Recurrent depressive disorder
1.6
6.0
138
882
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
6.0
412
3207
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
10.0
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
3149
24890
1.70
68.50
8.4
6.1
72.67
73.29
u/l
0.41
2992
23427
3959
33382
1.85
68.47
3.9
2.7
1.21
1.21
mmol/l
0.07
3806
31748
4651
41640
2.45
66.38
11.2
7.4
25.41
26.79
u/l
4.69
4562
40306
2604
19681
1.66
66.32
8.6
6.2
0.18
0.18
e9/l
0.23
2389
17594
2526
18961
1.66
65.93
8.0
5.9
0.54
0.54
e9/l
0.21
2298
16717
2527
18985
1.66
65.61
8.1
5.9
0.04
0.04
e9/l
1.42
2301
16712
2410
17959
1.65
64.05
8.6
6.3
—
—
—
0
0
751
4036
2.01
60.73
2.2
1.6
—
—
—
0
0
2604
19959
1.62
60.47
8.1
5.8
1.98
2.03
e9/l
1.56
2415
18050
938
5461
1.88
59.71
3.5
2.4
5880.33
6820.91
u/l
0.32
241
2248
4070
35095
1.81
59.14
4.2
3.0
4.56
4.65
mmol/l
8.33
3925
33519
2766
21712
1.60
56.62
10.9
8.2
4.00
3.96
e9/l
0.36
2500
19035
3225
26368
1.61
54.73
4.5
3.4
8.73
8.09
mm/h
2.54
3045
24565
1833
13283
1.59
50.96
8.7
5.8
1.22
1.21
mmol/l
1.31
1574
11350
1942
14279
1.58
50.65
2.7
2.2
71.60
69.73
nmol/l
2.01
1836
13371
1660
11785
1.61
50.12
6.3
4.7
37.43
37.48
g/l
0.15
1548
10984
1169
7635
1.69
48.98
5.8
3.5
7.39
7.39
ph
1.58
224
1473
1663
11904
1.59
48.02
8.1
5.4
1.22
1.22
mmol/l
1.44
1535
10970
2249
17255
1.54
47.65
8.1
6.0
0.66
0.65
%
0.54
2138
16198
2323
17975
1.54
47.17
8.0
5.9
2.68
2.76
%
1.07
2216
16952
2336
18105
1.54
47.03
8.3
6.1
8.07
8.04
%
0.21
2235
17097
2401
18852
1.52
44.64
7.7
5.7
55.86
55.56
%
0.71
2297
17886
2424
19142
1.51
43.38
8.0
5.8
29.90
30.49
%
2.18
2320
18167
2017
15341
1.52
43.10
5.7
5.1
9.94
10.36
umol/l
1.17
1891
14315
858
5325
1.73
42.69
1.4
1.4
494.17
545.70
titre
0.43
144
962
1122
7493
1.64
42.23
2.0
1.5
1.34
1.36
mmol/l
0.23
1023
6630
1014
6676
1.65
40.13
3.1
2.7
123.17
112.73
ug/g
0.43
798
5220
1382
9816
1.56
39.70
3.7
2.4
57.85
56.34
u/l
0.34
1273
9082
3973
35265
1.58
37.79
3.9
3.1
2.75
2.82
mmol/l
5.41
3780
33488
596
3448
1.82
37.38
10.6
6.3
1.09
1.08
mmol/l
0.25
569
3253
4126
37001
1.62
37.04
13.5
8.9
3.90
3.89
mmol/l
0.77
4013
35650
1225
8590
1.56
36.78
2.5
2.1
2.67
2.62
mg/l
0.34
1076
7386
3631
31707
1.51
36.13
4.3
3.8
14.49
14.38
pmol/l
2.10
3379
29062
1621
12128
1.49
35.71
1.5
1.4
1.71
1.74
u/ml
0.04
471
3283
4110
36914
1.60
35.64
13.4
8.8
139.47
139.50
mmol/l
0.39
4015
35673
731
4549
1.71
35.47
3.2
2.2
14.65
14.89
umol/l
0.39
687
4253
3920
34890
1.54
34.75
3.7
2.9
1.43
1.44
mmol/l
0.69
3746
33254
1449
10677
1.50
34.06
1.8
1.6
97.56
98.07
pmol/l
0.16
785
6020
661
4047
1.73
33.94
2.5
1.8
—
—
—
0
0
1401
10289
1.50
33.34
1.5
1.4
2.12
2.07
g/l
0.68
908
6543
533
3100
1.80
32.64
2.4
2.1
10.42
11.71
nmol/l
2.60
481
2855
1610
12235
1.46
31.95
3.5
3.0
31.30
29.70
u/l
0.57
1512
11653
1272
9257
1.50
31.29
3.0
2.7
2.35
2.35
mmol/l
0.29
1144
8420
658
4113
1.69
31.13
3.3
2.2
2.41
2.51
g/l
4.14
610
3810
1047
7343
1.53
30.61
2.3
2.1
212.46
255.43
u/l
0.42
987
6967
604
3718
1.71
30.21
3.6
2.3
24.22
24.33
%
0.07
530
3230
4039
36548
1.52
29.55
5.1
4.3
1.74
1.82
mu/l
1.02
3854
34559
600
3742
1.68
28.49
1.6
1.5
—
—
—
0
0
2141
17391
1.40
28.36
10.3
7.8
0.00
0.00
e9/l
0.71
1806
14259
4408
40777
1.62
28.15
13.8
9.2
18.93
20.28
mg/l
2.11
3372
30344
642
4113
1.64
27.41
5.0
4.1
0.82
0.83
mmol/l
2.03
608
3901
1410
10756
1.43
26.31
9.3
6.6
1.11
1.09
inr
0.63
499
3781
565
3559
1.66
25.70
2.1
1.9
393.31
385.86
nmol/l
0.36
527
3287
426
2489
1.77
25.49
4.8
4.0
0.52
0.53
%
0.05
137
658
379
2143
1.83
25.29
15.3
8.0
8.27
6.70
mmol/l
5.63
373
2055
829
5784
1.52
24.22
1.4
1.4
20.17
19.87
nmol/l
0.19
761
5194
431
2575
1.73
23.81
5.2
4.4
0.08
0.12
%
0.42
133
640
445
2689
1.72
23.60
5.1
4.3
0.82
0.79
%
0.07
148
752
285
1506
1.94
23.44
1.3
1.2
0.27
1.07
u/ml
1.59
20
110
2533
21550
1.35
23.36
3.5
2.8
74.04
70.36
ug/l
0.69
2402
20357
415
2482
1.73
22.82
5.3
4.4
0.14
0.38
%
0.52
116
543
2271
19061
1.34
22.66
5.6
4.2
6.33
6.19
mmol/l
1.73
2081
16866
1167
8819
1.42
22.32
8.2
6.6
—
—
—
0
0
1632
13052
1.37
22.20
2.0
1.8
—
—
—
0
0
595
3937
1.58
21.96
1.7
1.6
1235.60
1146.00
nmol/l
1.39
450
3055
1182
9061
1.39
20.55
2.9
2.5
39.91
61.15
ng/l
0.31
485
3711
59
154
3.86
19.99
2.2
1.7
—
—
—
0
0
65
185
3.54
19.44
27.2
25.9
106.53
132.50
ug/l
1.40
51
156
1117
8551
1.39
19.42
1.9
1.7
—
—
—
0
0
287
1629
1.80
18.88
7.0
4.2
110.92
70.19
ng/l
5.18
266
1487
852
6252
1.43
18.82
1.3
1.3
59.15
23.31
iu/ml
0.41
237
1771
449
2881
1.61
18.77
2.6
2.5
10.83
10.50
g/l
1.08
408
2653
1911
15946
1.32
18.63
3.5
2.7
5.93
6.01
ph
0.67
167
1610
896
6650
1.42
18.55
4.8
3.8
—
—
—
0
0
880
6519
1.42
18.40
3.6
2.3
6.16
8.44
e6/l
3.94
800
5780
2405
20750
1.30
18.14
3.1
2.6
—
—
—
0
0
353
2153
1.68
18.01
3.8
3.0
—
—
—
0
0
1304
10337
1.35
17.99
4.4
3.1
0.01
0.00
estimate
0.33
480
3990
1036
7926
1.38
17.89
4.5
3.8
94.35
94.65
%
0.16
1005
7707
532
3589
1.54
17.86
2.7
3.0
5.79
6.54
umol/l
0.62
450
3021
403
2550
1.63
17.81
3.7
3.5
1.67
1.64
%
0.21
361
2290
3683
33719
1.33
17.61
3.5
2.9
5.59
5.54
mmol/l
1.19
3453
31517
3266
29412
1.31
17.53
4.8
3.6
37.18
36.84
mmol/mol
1.14
3098
27876
4557
43253
1.53
17.52
12.2
8.4
—
—
—
0
0
598
4162
1.49
17.29
2.9
2.4
2.41
2.40
mmol/l
0.30
517
3614
2255
19370
1.29
17.28
4.0
3.0
0.01
0.00
estimate
0.30
478
3993
455
2993
1.57
17.08
1.8
1.4
—
—
—
0
0
2243
19281
1.29
16.98
4.0
2.9
0.00
0.00
estimate
1.54
498
4128
223
1212
1.88
16.87
2.1
1.9
0.21
0.22
g/l
0.64
207
1156
394
2513
1.61
16.85
2.4
2.8
0.23
0.23
g/l
0.65
366
2350
486
3255
1.54
16.83
1.5
1.4
—
—
—
0
0
2239
19273
1.29
16.66
5.2
4.1
0.00
0.00
estimate
0.80
495
4104
2992
26731
1.29
16.53
4.8
3.6
—
—
—
0
0
1497
12237
1.31
16.41
4.6
3.2
78.56
64.60
e6/l
0.27
1044
7762
1109
8679
1.35
16.41
3.9
2.7
0.30
0.26
e6/l
0.26
857
6327
3968
36852
1.35
16.38
16.5
11.3
13.93
14.43
%
1.15
3903
36108
3162
28490
1.29
16.14
3.3
2.7
33.72
33.79
u/l
0.02
3034
27269
589
4141
1.48
16.14
3.5
3.0
1368.17
622.86
ng/l
2.40
463
3227
1208
9599
1.34
16.10
4.1
2.7
119.78
97.87
e6/l
0.16
956
7103
1129
8894
1.34
15.93
4.2
3.4
8.42
8.82
mmol/l
1.56
1026
7973
224
1242
1.84
15.93
2.1
1.9
1.11
1.16
g/l
1.92
208
1189
474
3212
1.52
15.52
1.3
1.3
282.85
255.39
u/ml
0.21
444
2971
1076
8444
1.35
15.52
4.0
2.9
—
—
—
0
0
41
100
4.12
15.29
2.7
2.8
—
—
—
0
0
532
3704
1.49
15.28
1.2
1.2
—
—
—
0
0
1105
8738
1.34
15.08
3.9
3.0
1.02
1.02
kg/l
0.08
141
1271
2854
25497
1.27
15.05
4.6
3.7
217.10
1439.83
e6/l
2.81
41
299
571
4044
1.46
15.03
3.0
2.6
29.71
29.49
s
0.47
555
3910
180
954
1.92
14.74
1.2
1.3
15.35
27.20
u/ml
0.55
13
56
113
503
2.27
14.72
1.1
1.2
6.59
6.27
umol/l
0.37
102
469
153
767
2.02
14.71
4.4
3.8
56.38
55.34
%
0.53
153
767
753
5627
1.39
14.70
4.6
3.6
851.74
349.72
mg/l
1.33
545
3964
730
5430
1.40
14.64
1.6
1.5
102992554.87
39377671.66
pmol/l
1.01
635
4721
774
5837
1.38
14.27
1.3
1.2
7.05
9.03
u/ml
0.56
315
2403
381
2511
1.56
14.15
6.1
4.5
7.38
7.37
ph
—
6
21
376
2474
1.56
14.06
6.1
4.5
6.00
5.90
kpa
1.21
367
2389
280
1719
1.66
13.94
3.2
3.1
73.55
71.30
e9/l
0.44
207
1219
353
2295
1.58
13.91
11.8
8.8
—
—
—
0
0
372
2455
1.55
13.73
6.2
4.6
1.56
1.67
mmol/l
0.27
311
2035
809
6190
1.36
13.58
3.7
2.4
530.87
567.90
mosm/kgh2o
4.38
713
5310
1099
8808
1.31
13.44
3.8
2.6
—
—
—
0
0
336
2188
1.57
13.15
1.6
1.7
1.24
1.29
g/l
0.33
307
2036
766
5844
1.36
13.06
5.6
4.2
14.88
12.03
mg/mmol
0.52
545
4125
207
1193
1.76
12.99
1.2
1.1
—
—
—
0
0
310
1987
1.59
12.99
5.9
3.1
1.22
1.23
mmol/l
0.17
268
1707
92
399
2.33
12.78
3.2
2.2
—
—
—
0
0
45
134
3.37
12.67
5.5
4.4
—
—
—
0
0
161
868
1.88
12.57
1.2
1.3
24.12
16.22
u/ml
0.26
23
131
191
1092
1.78
12.34
7.6
6.4
1.50
1.19
mg/l
5.08
185
1034
331
2183
1.55
12.26
9.7
7.5
1.22
1.37
mmol/l
2.51
324
2130
856
6701
1.33
12.24
2.9
2.3
1730.07
3281.04
umol/l
1.24
785
6122
223
1349
1.68
11.78
3.4
3.2
3.52
3.55
g/l
0.10
211
1279
317
2090
1.55
11.76
5.0
4.2
4.88
4.82
kpa
0.17
308
2018
227
1383
1.67
11.68
2.3
2.0
67.48
67.72
g/l
0.18
215
1302
156
855
1.85
11.60
1.3
1.3
5.56
3.62
u/ml
0.22
17
84
1204
9934
1.28
11.53
2.7
2.2
—
—
—
0
0
658
5001
1.36
11.40
3.1
2.4
0.99
1.10
e6/l
0.32
373
2586
71
290
2.46
11.31
3.0
3.0
83.46
141.23
au/ml
0.76
11
46
229
1412
1.65
11.26
2.2
2.2
7.41
6.80
ug/l
0.17
204
1226
982
7917
1.30
11.25
2.3
1.9
0.82
0.98
mg/l
1.72
685
5505
435
3090
1.44
11.20
1.4
1.3
—
—
—
0
0
579
4332
1.38
11.06
1.2
1.2
—
—
—
0
0
75
318
2.38
11.02
4.2
3.5
8.79
8.51
mg/l
0.14
61
264
278
1810
1.56
10.92
1.7
1.7
—
—
—
0
0
221
1371
1.64
10.62
1.4
1.3
236.39
226.98
u/ml
0.20
144
832
179
1050
1.73
10.62
4.7
3.3
1.51
1.44
%
0.29
179
1045
198
1194
1.68
10.62
1.8
1.4
19.92
20.99
u/ml
—
5
25
379
2650
1.46
10.60
1.4
1.2
—
—
—
0
0
144
793
1.84
10.58
1.2
1.3
24.48
42.92
u/ml
0.59
14
57
93
442
2.12
10.43
7.7
3.1
—
—
—
0
0
826
6578
1.30
10.30
2.8
2.5
—
—
—
0
0
131
707
1.87
10.27
1.4
1.3
270.15
323.02
ug/g
1.64
69
340
170
996
1.73
10.15
2.0
1.6
—
—
—
0
0
4834
47067
1.59
10.11
20.5
13.5
40.66
40.85
%
0.63
4636
44867
239
1541
1.58
9.82
2.5
2.6
21.26
20.97
s
0.44
191
1291
194
1191
1.65
9.74
1.8
1.4
—
—
—
0
0
487
3617
1.38
9.71
1.7
1.6
338.29
319.11
mu/l
0.51
435
3235
4835
47113
1.57
9.66
20.4
13.5
263.09
260.99
e9/l
1.58
4752
45937
4842
47198
1.58
9.64
20.3
13.5
6.72
6.78
e9/l
1.00
4748
45945
81
377
2.16
9.61
3.1
3.0
1.27
1.32
%
0.06
73
344
185
1127
1.66
9.58
1.8
1.4
108.16
107.64
u/ml
0.03
39
195
246
1608
1.55
9.52
1.1
1.1
4.90
4.28
u/ml
0.14
35
249
4839
47175
1.57
9.47
20.2
13.4
89.36
89.09
fl
4.54
4794
46584
4840
47190
1.57
9.43
20.3
13.4
4.59
4.60
e12/l
0.91
4749
45966
4839
47180
1.57
9.40
20.2
13.4
29.92
29.86
pg
1.70
4793
46589
4842
47216
1.57
9.40
20.4
13.5
136.83
136.93
g/l
0.21
4798
46622
139
787
1.79
9.37
5.7
4.3
—
—
—
0
0
2112
18849
1.20
9.21
2.4
2.1
—
—
—
0
0
288
1965
1.49
9.14
10.6
9.2
96.02
96.60
%
0.63
280
1886
324
2266
1.46
9.07
9.9
8.5
0.13
0.57
mmol/l
1.02
249
1694
295
2028
1.48
9.02
1.3
1.3
—
—
—
0
0
52
205
2.55
9.00
2.0
2.5
10.13
9.87
mg/l
0.11
41
173
359
2564
1.43
8.98
1.4
1.6
7.68
7.62
u/l
0.04
289
2130
677
5354
1.30
8.82
1.5
1.5
—
—
—
0
0
146
854
1.73
8.82
2.4
2.6
—
—
—
0
0
161
969
1.68
8.76
2.2
1.9
163.42
192.96
pmol/l
1.95
155
925
354
2540
1.42
8.64
2.0
2.0
5.10
4.90
e9/l
0.08
304
2200
196
1245
1.59
8.62
2.1
1.6
10.83
12.37
u/ml
—
9
56
321
2264
1.44
8.61
9.9
8.5
13.68
14.04
kpa
0.52
306
2159
99
518
1.93
8.59
2.8
2.6
330.63
128.97
ug/min
1.19
73
344
321
2265
1.44
8.59
9.9
8.5
5.03
5.02
kpa
0.05
305
2158
1673
14682
1.21
8.55
2.4
2.0
—
—
—
0
0
142
835
1.72
8.43
2.9
2.5
445.22
387.40
ug/l
0.10
127
741
118
658
1.81
8.41
2.0
2.1
2.08
1.99
ug/l
0.03
107
590
271
1861
1.48
8.35
11.1
9.3
122.67
125.13
g/l
1.06
266
1807
525
4059
1.33
8.04
1.3
1.2
93.81
145.64
iu/ml
3.50
199
1495
324
2320
1.42
8.01
1.2
1.2
—
—
—
0
0
42
159
2.65
7.92
1.9
2.0
94.60
146.68
au/ml
—
5
21
579
4556
1.30
7.80
3.4
2.8
367.17
514.41
ng/l
0.48
298
2276
417
3131
1.36
7.77
1.4
1.5
15.69
16.07
iu/l
0.11
338
2636
301
2150
1.42
7.56
1.1
1.1
—
—
—
0
0
143
869
1.66
7.56
1.9
2.1
10.14
9.79
mg/l
0.22
136
824
376
2790
1.37
7.55
1.2
1.1
72.50
196.62
titre
1.79
14
77
232
1580
1.49
7.48
1.6
1.7
—
—
—
0
0
609
4855
1.29
7.42
3.3
2.5
2.70
4.02
e6/l
3.13
324
2435
126
2055
0.60
7.35
1.2
1.2
—
—
—
0
0
251
1745
1.46
7.30
4.2
3.5
5.03
5.14
kpa
1.51
239
1671
368
2741
1.37
7.22
3.3
3.4
4.62
4.70
pmol/l
0.94
327
2480
249
1734
1.46
7.18
4.2
3.5
7.40
7.41
ph
0.39
41
203
133
805
1.67
7.16
1.1
1.1
—
—
—
0
0
289
3953
0.71
7.10
1.3
1.4
—
—
—
0
0
402
3052
1.34
6.98
3.5
2.5
33.64
51.59
u/l
0.59
354
2620
405
5230
0.75
6.82
1.4
1.4
—
—
—
0
0
153
973
1.59
6.78
1.4
1.4
10.08
14.64
u/l
2.38
135
846
484
3790
1.30
6.76
1.2
1.2
—
—
—
0
0
155
994
1.57
6.63
2.3
2.1
1.27
1.25
g/l
0.12
141
865
174
1146
1.53
6.62
1.6
1.6
—
—
—
0
0
81
437
1.86
6.51
11.5
11.1
0.60
0.59
mmol/l
0.21
73
397
15
22
6.82
6.49
4.3
9.7
215.71
82.08
e6/l
—
7
12
522
4162
1.28
6.35
2.2
2.2
—
—
—
0
0
162
1062
1.54
6.31
1.3
1.4
74.78
81.97
titre
0.19
23
117
22
66
3.34
6.25
3.0
3.1
74.55
13.21
mg/l
—
6
18
106
628
1.70
6.23
7.2
2.8
—
—
—
0
0
186
1260
1.49
6.22
13.5
10.7
94.38
94.46
%
0.06
186
1252
75
403
1.87
6.12
1.3
1.3
0.42
0.40
g/l
0.24
53
277
225
3129
0.70
6.12
1.3
1.5
—
—
—
0
0
180
1217
1.49
6.08
1.2
1.1
—
—
—
0
0
75
404
1.87
6.08
1.3
1.3
6.45
6.58
g/l
0.13
53
282
75
404
1.87
6.08
1.3
1.3
3.24
2.83
g/l
1.32
53
280
35
139
2.52
6.07
1.1
1.1
—
—
—
0
0
191
1308
1.48
6.06
3.4
2.8
116.25
106.58
ng/l
0.16
162
1112
225
3122
0.71
6.04
1.3
1.5
—
—
—
0
0
80
441
1.82
6.03
2.2
1.7
33.40
32.95
iu/ml
—
5
20
65
335
1.95
6.02
1.3
1.3
—
—
—
0
0
109
658
1.67
5.99
1.5
1.7
0.63
0.72
g/l
0.55
85
502
35
140
2.51
5.99
1.0
1.0
—
—
—
0
0
167
1118
1.51
5.93
4.4
3.6
0.34
0.37
g/l
0.12
99
562
162
1080
1.51
5.87
14.3
11.3
23.59
24.03
mmol/l
1.00
156
1050
74
402
1.85
5.86
1.3
1.3
—
—
—
0
0
234
3207
0.72
5.84
1.3
1.5
—
—
—
0
0
16
30
5.34
5.82
10.3
5.3
5.66
6.13
mmol/l
0.22
16
30
345
2639
1.33
5.72
2.4
2.3
17.41
19.65
au/ml
0.27
28
271
70
379
1.86
5.62
1.2
1.4
193.14
188.25
pmol/l
0.10
70
379
120
759
1.59
5.51
1.4
1.3
5.84
4.18
u/ml
0.40
58
349
461
3690
1.27
5.44
2.7
2.9
—
—
—
0
0
76
428
1.78
5.39
1.0
1.0
—
—
—
0
0
170
1168
1.47
5.35
5.0
5.5
—
—
—
0
0
389
3060
1.29
5.28
1.3
1.3
231.62
231.78
miu/ml
0.00
192
1518
59
309
1.92
5.26
1.1
1.1
1849.77
1404.92
miu/ml
1.79
59
309
199
1415
1.42
5.22
3.7
2.4
0.11
0.21
e6/l
3.17
193
1359
119
765
1.57
5.13
1.1
1.1
—
—
—
0
0
148
998
1.50
5.13
1.1
1.2
—
—
—
0
0
1307
11638
1.16
5.10
3.3
2.5
—
—
—
0
0
298
2272
1.33
5.09
2.9
2.8
—
—
—
0
0
171
1190
1.45
5.06
7.1
7.2
23.93
23.90
mmol/l
0.04
165
1120
306
2349
1.32
4.99
4.6
3.2
—
—
—
0
0
76
439
1.74
4.97
1.6
1.4
—
—
—
0
0
162
1120
1.46
4.96
14.3
11.5
—
—
—
0
0
3990
38443
1.17
4.96
16.8
11.2
333.78
334.16
g/l
1.90
3949
38066
82
485
1.70
4.93
1.7
1.7
16145.97
11715.13
e6/l
0.36
62
372
53
274
1.94
4.93
1.3
1.4
—
—
—
0
0
590
4913
1.23
4.91
2.1
2.2
—
—
—
0
0
1244
11070
1.16
4.86
2.4
2.1
—
—
—
0
0
112
720
1.57
4.85
1.1
1.1
113.69
115.25
%
0.22
98
645
48
242
1.99
4.80
1.2
1.2
—
—
—
0
0
78
459
1.71
4.79
1.6
1.5
—
—
—
0
0
259
1956
1.34
4.74
1.5
1.4
—
—
—
0
0
46
230
2.01
4.72
1.6
1.5
1.17
1.42
nmol/l
0.90
40
215
34
151
2.26
4.70
1.8
1.7
3.44
3.00
mg/l
0.17
34
144
39
184
2.12
4.66
1.0
1.2
—
—
—
0
0
33
147
2.25
4.54
12.3
5.3
5349.36
76.74
mg/l
0.48
25
110
132
894
1.49
4.52
1.1
1.1
2.81
2.65
u/ml
0.09
61
463
34
155
2.20
4.43
1.1
1.1
3.67
4.00
iu/ml
—
6
20
315
2469
1.29
4.43
1.3
1.2
33.12
42.23
au/ml
—
6
108
52
278
1.88
4.42
1.3
1.3
5.08
5.60
ug/l
0.32
47
245
45
229
1.97
4.42
1.1
1.1
—
—
—
0
0
951
8349
1.17
4.39
2.4
2.0
—
—
—
0
0
113
746
1.52
4.38
1.2
1.3
—
—
—
0
0
112
748
1.51
4.14
7.3
3.2
7.41
7.41
ph
0.22
103
678
84
527
1.60
4.09
2.4
3.0
29.86
31.82
umol/l
0.53
78
490
625
5332
1.19
4.05
2.1
2.1
—
—
—
0
0
614
5236
1.19
4.00
2.1
2.1
—
—
—
0
0
69
415
1.67
3.98
1.2
1.3
—
0.38
nmol/l
—
0
10
619
5285
1.19
3.97
2.1
2.1
—
—
—
0
0
37
183
2.03
3.96
1.5
1.3
77576.79
43439.19
e6/l
0.23
29
124
16
53
3.02
3.95
1.5
1.9
—
—
—
0
0
99
653
1.52
3.90
7.7
3.2
2.09
1.93
mmol/l
0.26
62
371
622
5324
1.19
3.88
2.1
2.0
—
—
—
0
0
28
125
2.24
3.87
1.2
1.1
—
—
—
0
0
84
535
1.58
3.86
3.4
2.2
17.42
17.45
%
0.02
53
252
51
284
1.80
3.86
3.6
3.0
—
—
—
0
0
72
443
1.63
3.82
12.5
15.3
818.67
793.57
nmol/l
0.18
66
430
62
367
1.70
3.81
1.1
1.3
—
—
—
0
0
97
642
1.52
3.77
2.8
2.1
136.35
133.64
g/l
0.60
78
503
6
5
11.99
3.76
6.8
3.4
1.07
0.36
g/l
—
6
5
73
453
1.62
3.75
19.1
22.1
1397.82
1386.47
nmol/l
0.04
68
438
523
4426
1.20
3.71
3.4
3.3
1.70
1.65
ug/l
0.05
482
4055
127
893
1.43
3.66
1.2
1.1
10.97
11.88
au/ml
—
9
64
450
3762
1.21
3.63
4.6
3.1
—
—
—
0
0
118
822
1.44
3.58
2.6
2.7
—
—
—
0
0
94
626
1.51
3.57
5.0
5.5
374.97
375.45
umol/l
0.01
76
550
11
26
4.23
3.49
1.0
1.1
—
—
—
0
0
57
342
1.67
3.37
3.4
2.5
53.48
27.95
mg/l
2.24
46
274
57
342
1.67
3.37
3.4
2.5
67.76
55.87
mg/l
0.25
46
275
24
107
2.25
3.36
1.1
1.2
—
—
—
0
0
130
937
1.40
3.30
1.4
1.4
3.56
3.55
mmol/l
0.06
125
872
109
762
1.44
3.28
5.2
6.1
0.97
0.94
%
0.28
101
705
38
204
1.87
3.27
1.1
1.1
—
—
—
0
0
84
559
1.51
3.24
5.4
3.9
—
—
—
0
0
491
4187
1.19
3.22
1.4
1.3
—
—
—
0
0
41
227
1.81
3.21
3.2
3.6
203.50
181.28
umol/l
0.19
16
127
173
1311
1.33
3.20
1.2
1.1
—
—
—
0
0
45
257
1.75
3.19
2.1
3.4
—
—
—
0
0
26
123
2.12
3.18
1.1
1.0
0.21
0.15
u/ml
0.12
19
75
144
1063
1.36
3.17
1.5
1.5
435.13
431.44
mg/l
0.04
137
1004
26
124
2.10
3.12
1.7
1.7
—
—
—
0
0
58
358
1.62
3.10
1.2
1.1
1.12
1.05
ratio
0.43
18
139
43
245
1.76
3.08
1.4
1.5
—
—
—
0
0
49
291
1.69
3.04
1.6
1.8
76.20
72.42
mmol/l
0.18
40
249
33
174
1.90
3.02
1.0
1.1
—
—
—
0
0
197
1537
1.29
2.98
1.1
1.1
3.05
2.73
u/ml
0.14
129
860
50
302
1.66
2.93
1.0
1.0
20.85
15.35
u/ml
0.55
34
178
92
638
1.45
2.93
11.0
2.6
0.93
0.80
nmol/l
0.58
75
553
128
943
1.36
2.89
1.5
1.5
1761.18
4745.41
e6/l
0.34
107
761
128
943
1.36
2.89
1.5
1.5
11.57
20.84
e6/l
1.11
104
727
221
1758
1.27
2.88
1.2
1.1
2.01
2.82
u/ml
0.72
135
954
18
76
2.37
2.88
2.6
1.8
—
—
—
0
0
71
470
1.52
2.85
2.1
2.2
—
—
—
0
0
34
187
1.82
2.76
2.0
1.4
4.95
6.54
u/l
1.20
24
153
44
263
1.68
2.70
3.4
2.5
—
—
—
0
0
84
583
1.45
2.69
3.1
2.9
—
—
—
0
0
106
772
1.38
2.60
5.2
6.0
1.73
1.76
%
0.10
99
713
7
15
4.66
2.59
1.1
1.2
—
—
—
0
0
21
100
2.10
2.57
2.9
2.8
7.41
7.42
ph
—
6
24
54
345
1.57
2.57
3.1
5.3
6.79
6.64
mmol/l
0.08
44
272
34
192
1.77
2.56
1.8
3.2
—
—
—
0
0
105
767
1.37
2.54
1.2
1.2
—
—
—
0
0
164
1279
1.29
2.54
4.3
3.9
—
—
—
0
0
23
115
2.00
2.49
1.9
1.7
—
—
—
0
0
197
1577
1.26
2.48
1.1
1.1
7.30
8.10
u/ml
0.23
113
928
7
16
4.37
2.47
1.1
1.2
—
—
—
0
0
22
109
2.02
2.44
1.4
1.6
—
—
—
0
0
126
954
1.33
2.43
11.2
6.5
—
—
—
0
0
58
383
1.52
2.41
1.4
1.5
366.23
677.99
pmol/l
0.61
53
339
139
1070
1.31
2.39
2.0
2.1
—
—
—
0
0
66
450
1.47
2.36
1.8
2.0
4.84
5.09
mmol/24h
0.30
60
414
1899
17952
1.09
2.30
2.7
2.5
—
—
—
0
0
29
162
1.79
2.29
1.6
1.2
86.00
86.36
nmol/24h
0.01
29
162
360
3088
1.18
2.27
3.1
2.8
32.55
31.80
%
0.66
274
2365
6
13
4.61
2.27
1.2
1.5
466.33
1970.92
nmol/l
—
6
13
155
1223
1.27
2.23
1.4
1.3
—
—
—
0
0
66
456
1.45
2.22
1.7
1.5
—
—
—
0
0
209
1708
1.23
2.22
2.1
2.2
43.91
33.37
u/ml
0.24
202
1645
23
121
1.90
2.19
1.2
1.2
—
—
—
0
0
199
1621
1.23
2.18
1.3
1.3
—
—
—
0
0
8
24
3.33
2.17
1.1
1.1
—
—
—
0
0
32
189
1.69
2.12
1.2
1.2
—
—
—
0
0
36
220
1.64
2.10
3.0
2.8
1.94
1.71
g/24h
0.19
24
136
15
68
2.21
2.10
1.1
1.5
—
—
—
0
0
9
31
2.90
2.06
1.4
1.5
94.62
101.13
ng/l
—
9
31
17
82
2.07
2.05
1.6
1.4
—
—
—
0
0
7
20
3.50
2.05
1.1
1.2
—
—
—
0
0
43
277
1.55
2.04
1.2
1.1
6.77
37.42
u/ml
0.50
26
180
24
132
1.82
2.02
1.0
1.1
—
—
—
0
0
184
1501
1.23
2.02
1.1
1.1
0.98
1.43
u/ml
0.71
100
732
69
491
1.41
2.01
2.9
2.7
—
—
—
0
0
47
310
1.52
2.01
1.8
1.9
290.17
288.05
mosm/kgh2o
0.22
35
240
149
1188
1.26
2.00
4.3
3.9
24.16
24.44
mmol/l
0.77
142
1146
17
83
2.05
2.00
4.5
3.4
55.28
46.48
%
0.84
17
78
144
1144
1.26
1.99
1.8
2.1
2.54
4.12
iu/l
4.77
47
480
513
5732
0.88
1.99
1.9
2.1
—
—
—
0
0
9
32
2.81
1.99
2.8
1.7
13.22
19.22
nmol/l
—
9
32
25
140
1.79
1.99
1.2
1.0
—
—
—
0
0
25
140
1.79
1.99
1.2
1.0
—
—
—
0
0
25
140
1.79
1.99
1.2
1.0
—
—
—
0
0
15
70
2.14
1.97
1.3
1.0
4.49
12.06
u/ml
—
10
50
167
1354
1.24
1.95
1.6
1.6
0.38
0.46
nmol/l
0.77
142
1136
11
45
2.44
1.92
1.4
1.2
38.22
37.73
g/l
—
6
30
295
2532
1.17
1.90
2.5
2.3
0.56
0.64
ug/l
1.25
154
1289
16
78
2.05
1.90
3.5
4.5
28.00
22.33
mg/l
0.85
16
73
33
204
1.62
1.87
1.9
3.8
—
—
—
0
0
52
357
1.46
1.86
2.1
1.8
92.02
91.71
%
0.22
52
352
202
1682
1.21
1.84
1.1
1.1
—
—
—
0
0
600
6607
0.89
1.84
1.2
1.3
—
—
—
0
0
31
190
1.63
1.82
1.1
1.1
—
—
—
0
0
5
12
4.16
1.82
1.0
1.2
—
—
—
0
0
5
12
4.16
1.82
1.0
1.1
—
—
—
0
0
49
335
1.46
1.80
1.1
1.1
—
—
—
0
0
31
191
1.62
1.79
1.5
1.5
41.02
39.80
%
0.06
20
124
45
303
1.49
1.78
1.0
1.1
—
—
—
0
0
48
328
1.47
1.77
1.1
1.1
—
—
—
0
0
37
239
1.55
1.77
3.7
4.3
—
—
—
0
0
23
131
1.76
1.76
1.0
1.2
—
—
—
0
0
14
67
2.09
1.75
1.5
1.3
—
—
—
0
0
156
1277
1.23
1.70
1.1
1.1
7.65
4.53
u/ml
0.39
91
696
11
48
2.29
1.69
2.8
1.7
—
—
—
0
0
54
382
1.42
1.68
1.3
1.2
—
—
—
0
0
53
374
1.42
1.67
2.8
3.1
37073.04
39922.10
ug/l
1.15
53
374
32
203
1.58
1.66
1.2
1.1
13.45
7.67
u/ml
0.25
24
153
6
19
3.16
1.66
1.0
1.0
—
—
—
0
0
57
409
1.40
1.64
1.7
1.6
—
—
—
0
0
20
112
1.79
1.63
1.2
1.0
23.88
4.17
u/ml
0.40
12
61
47
327
1.44
1.61
1.1
1.1
—
—
—
0
0
43
294
1.46
1.61
1.1
1.2
—
—
—
0
0
35
229
1.53
1.61
5.1
4.9
10.87
11.68
%
1.13
35
229
20
113
1.77
1.59
1.2
1.0
0.32
0.76
u/ml
0.37
12
63
6
20
3.00
1.58
1.3
1.5
350.77
595.84
nmol/l
—
6
20
107
851
1.26
1.54
1.8
1.8
—
—
—
0
0
18
100
1.80
1.52
1.2
1.5
12.22
12.66
u/l
0.08
18
100
7
27
2.59
1.51
1.1
1.0
—
—
—
0
0
112
899
1.25
1.50
1.7
1.5
—
—
—
0
0
45
316
1.43
1.49
1.1
1.1
9.61
6.30
iu/ml
—
8
81
65
486
1.34
1.48
2.4
3.5
21.25
30.27
mu/l
1.69
57
449
15
79
1.90
1.48
6.5
9.4
—
—
—
0
0
136
1117
1.22
1.48
1.1
1.1
—
—
—
0
0
32
211
1.52
1.44
1.3
1.5
—
—
—
0
0
39
270
1.45
1.40
1.5
2.2
—
—
—
0
0
37
255
1.45
1.37
1.1
1.1
—
—
—
0
0
19
112
1.70
1.34
2.7
2.6
0.94
0.95
nmol/l
0.01
14
80
62
469
1.32
1.34
1.5
1.8
—
—
—
0
0
82
645
1.27
1.33
1.3
1.2
—
—
—
0
0
51
375
1.36
1.32
2.9
2.5
1.42
1.39
mmol/l
0.07
51
364
48
350
1.37
1.31
1.4
1.5
—
—
—
0
0
134
1117
1.20
1.29
1.1
1.1
—
—
—
0
0
12
62
1.93
1.27
2.7
3.2
3.74
3.42
mg/l
0.21
12
62
15
84
1.79
1.26
1.1
1.0
4.13
1.78
u/ml
—
8
49
1544
14773
1.06
1.22
1.8
1.8
—
—
—
0
0
24
155
1.55
1.22
1.4
1.5
151.88
131.87
nmol/l
1.26
24
155
37
262
1.41
1.21
1.4
1.1
—
—
—
0
0
52
391
1.33
1.19
1.0
1.0
—
—
—
0
0
60
463
1.30
1.16
7.3
8.2
12.15
11.50
mmol/l
0.73
54
411
45
333
1.35
1.15
3.0
2.6
7.72
7.02
mmol/l
0.25
45
328
965
9110
1.07
1.15
1.6
1.5
—
—
—
0
0
17
102
1.67
1.15
1.2
1.0
0.24
0.79
u/ml
0.78
11
62
5
20
2.50
1.15
3.0
1.8
—
—
—
0
0
60
464
1.29
1.14
7.3
8.2
106.09
105.69
mmol/l
0.27
54
412
95
777
1.22
1.14
5.7
5.8
1.26
1.18
mmol/l
0.50
86
677
20
126
1.59
1.13
1.8
1.7
—
—
—
0
0
72
572
1.26
1.12
1.5
1.4
—
—
—
0
0
25
167
1.50
1.11
1.4
1.2
—
—
—
0
0
19
119
1.60
1.10
1.6
1.8
85.80
149.12
ug/min
—
5
26
13
73
1.78
1.10
1.2
1.9
112.37
28.57
ng/l
—
7
38
48
363
1.32
1.08
1.2
1.3
—
—
—
0
0
8
41
1.95
1.08
1.1
1.0
—
—
—
0
0
166
1445
1.15
1.01
4.2
4.1
6.06
41.78
ug/l
0.77
130
1025
10
53
1.89
1.00
1.0
3.1
—
—
—
0
0
61
484
1.26
0.99
1.2
1.1
277.76
214.92
mg/l
0.60
55
413
0
29
0.00
0.97
0.0
1.1
—
—
—
0
0
63
503
1.25
0.97
1.4
1.1
58.31
37.63
mg/l
0.84
54
410
20
132
1.51
0.96
2.5
2.6
—
—
—
0
0
10
54
1.85
0.96
2.8
2.0
—
—
—
0
0
29
207
1.40
0.95
2.8
2.8
0.11
0.16
e9/l
0.85
29
201
1519
15716
0.95
0.94
1.7
1.8
—
—
—
0
0
85
706
1.21
0.92
1.2
1.1
98.46
2314.70
iu/ml
0.93
26
211
53
418
1.27
0.91
2.6
2.7
1.35
1.28
e9/l
0.19
43
356
21
302
0.69
0.90
5.0
3.6
18.90
22.59
u/ml
0.31
21
294
47
367
1.28
0.88
2.5
3.1
—
—
—
0
0
135
1173
1.15
0.87
1.1
1.1
4.58
7.51
u/ml
1.26
69
553
32
237
1.35
0.87
1.4
1.5
—
—
—
0
0
44
342
1.29
0.86
2.3
2.7
697.76
498.48
e6/l
1.13
34
275
20
136
1.47
0.85
1.1
1.1
31.74
274.73
ng/l
—
8
26
12
72
1.67
0.84
2.3
1.7
—
—
—
0
0
95
807
1.18
0.83
1.2
1.1
—
—
—
0
0
52
416
1.25
0.82
1.2
1.3
—
—
—
0
0
43
338
1.27
0.79
2.3
2.8
0.19
0.20
e9/l
0.12
33
278
0
25
0.00
0.79
0.0
1.1
—
35.64
—
0
25
11
66
1.67
0.78
1.4
1.1
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
70.87
—
0
27
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
0
28
0.00
0.76
0.0
1.1
—
0.56
—
0
5
30
227
1.32
0.73
2.1
2.0
—
—
—
0
0
42
333
1.26
0.73
1.6
1.3
1.95
1.76
mmol/l
0.76
42
307
9
55
1.63
0.73
1.0
1.2
—
—
—
0
0
50
406
1.23
0.72
1.4
1.6
—
—
—
0
0
9
57
1.58
0.71
1.2
1.3
—
—
—
0
0
5
26
1.92
0.70
3.0
1.6
—
—
—
0
0
25
186
1.34
0.69
2.2
2.1
—
—
—
0
0
14
93
1.50
0.69
1.8
2.2
—
—
—
0
0
61
510
1.20
0.67
1.1
1.1
—
—
—
0
0
31
241
1.29
0.65
1.1
1.1
8.11
15.50
u/ml
—
5
53
7
44
1.59
0.65
2.0
2.1
5.06
2.50
ug/l
—
7
38
11
70
1.57
0.64
1.1
1.3
—
—
—
0
0
11
70
1.57
0.64
1.0
1.1
—
—
—
0
0
11
70
1.57
0.64
1.0
1.1
—
—
—
0
0
11
70
1.57
0.64
1.0
1.1
—
—
—
0
0
26
198
1.31
0.63
2.1
2.6
113.85
187.68
e6/l
0.92
13
112
24
181
1.33
0.62
1.3
1.4
129.00
167.85
mmol/24h
2.27
24
181
55
460
1.20
0.62
1.3
1.5
1.17
1.33
promille
0.39
41
348
22
164
1.34
0.61
1.1
1.1
0.87
6.48
u/ml
0.79
17
144
58
488
1.19
0.61
1.0
1.1
9.13
3.10
u/ml
0.78
21
146
12
175
0.68
0.60
3.5
2.2
—
—
—
0
0
18
130
1.38
0.60
2.8
2.2
—
—
—
0
0
16
113
1.42
0.60
1.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
0.02
—
0
16
22
166
1.32
0.58
1.0
1.2
6.66
0.68
u/ml
0.43
22
166
25
320
0.78
0.57
5.4
6.1
—
—
—
0
0
25
320
0.78
0.57
2.7
3.1
—
—
—
0
0
57
484
1.18
0.56
1.1
1.1
9.31
2.27
u/ml
0.38
25
198
11
73
1.51
0.55
2.2
2.5
—
—
—
0
0
1366
13278
1.04
0.55
1.9
1.8
—
—
—
0
0
21
159
1.32
0.54
1.3
1.3
—
—
—
0
0
6
40
1.50
0.51
3.0
6.8
—
—
—
0
0
9
64
1.40
0.51
3.3
2.6
1.18
1.19
mmol/l
—
9
56
300
3184
0.94
0.51
1.5
1.5
—
—
—
0
0
39
325
1.20
0.49
2.3
2.9
783.36
715.52
e6/l
0.40
39
318
7
45
1.55
0.48
1.3
1.3
—
—
—
0
0
33
271
1.22
0.48
1.6
1.6
53.21
49.39
%
0.22
22
184
164
1514
1.08
0.45
2.2
1.6
—
—
—
0
0
67
757
0.88
0.44
1.6
1.5
—
—
—
0
0
7
51
1.37
0.44
21.1
6.3
—
—
—
0
0
10
69
1.45
0.44
1.0
1.0
—
—
—
0
0
47
404
1.16
0.43
3.1
4.1
39.36
101.28
u/ml
1.37
19
128
76
849
0.89
0.43
3.4
2.1
—
—
—
0
0
170
1824
0.93
0.42
1.3
1.3
3.45
3.92
ug/l
0.74
162
1744
24
194
1.24
0.41
4.8
3.1
173.60
53.68
mg/l
0.69
18
144
0
15
0.00
0.41
0.0
1.1
—
129.70
—
0
10
5
33
1.51
0.41
1.4
1.1
—
—
—
0
0
27
222
1.22
0.40
3.4
2.9
42.47
44.25
%
0.20
12
110
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
10
71
1.41
0.39
1.3
1.2
—
—
—
0
0
15
192
0.78
0.38
1.3
1.6
—
—
—
0
0
12
89
1.35
0.37
1.0
1.3
—
—
—
0
0
47
411
1.14
0.36
1.8
1.5
—
—
—
0
0
65
581
1.12
0.36
5.0
3.9
22.52
2451.15
u/ml
0.80
52
497
6
45
1.33
0.33
1.0
1.2
—
—
—
0
0
14
109
1.28
0.33
1.6
1.5
—
—
—
0
0
6
46
1.30
0.33
1.2
1.1
—
—
—
0
0
381
3663
1.04
0.32
1.2
1.3
—
—
—
0
0
11
83
1.32
0.31
1.1
1.1
—
—
—
0
0
134
1252
1.07
0.31
3.5
2.4
—
—
—
0
0
7
53
1.32
0.30
1.1
1.2
—
—
—
0
0
109
1012
1.08
0.30
1.1
1.1
0.14
0.40
u/ml
1.68
39
285
10
75
1.33
0.30
1.4
1.2
—
—
—
0
0
8
106
0.75
0.29
1.0
1.1
—
—
—
0
0
10
76
1.31
0.28
1.0
1.1
—
—
—
0
0
35
309
1.13
0.26
1.3
1.2
—
—
—
0
0
12
95
1.26
0.26
1.2
1.1
—
—
—
0
0
15
123
1.22
0.25
3.2
1.3
—
—
—
0
0
12
96
1.25
0.24
1.5
1.5
—
—
—
0
0
14
115
1.22
0.23
2.7
1.8
—
—
—
0
0
26
294
0.88
0.22
3.6
2.1
—
—
—
0
0
80
747
1.07
0.22
3.3
2.8
26.31
24.33
mg/l
0.21
48
462
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
—
—
0
0
13
107
1.21
0.21
1.4
1.5
53375.40
20709.22
e6/l
—
5
63
0
12
0.00
0.21
0.0
2.3
—
25.50
—
0
6
0
12
0.00
0.21
0.0
1.5
—
2.50
—
0
12
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
6
50
1.20
0.19
1.2
1.0
880.33
797.60
ng/l
—
6
35
6
51
1.17
0.19
1.2
1.2
—
—
—
0
0
6
52
1.15
0.19
1.2
1.0
201.67
206.12
ng/l
—
6
38
67
714
0.94
0.19
1.4
1.4
28.71
32.36
nmol/l
0.70
61
655
14
119
1.18
0.17
1.4
1.5
2014.33
3570.74
e6/l
—
9
78
13
110
1.18
0.17
1.4
1.5
—
—
—
0
0
174
1678
1.04
0.16
2.0
2.4
5.72
5.50
umol/l
0.07
129
1253
12
101
1.19
0.16
1.0
1.0
—
—
—
0
0
37
340
1.09
0.16
1.0
1.3
4.86
3.29
u/ml
0.24
16
172
14
121
1.16
0.14
2.0
2.5
2.44
2.50
mmol/l
0.03
14
113
14
122
1.15
0.13
1.1
1.2
5.27
6.01
mmol/l
1.13
14
113
46
431
1.07
0.13
1.0
1.0
—
—
—
0
0
22
242
0.91
0.13
1.5
1.2
63.73
72.67
umol/l
2.83
22
242
44
466
0.94
0.12
1.1
1.0
1.12
1.23
u/ml
0.06
18
142
20
182
1.10
0.10
1.4
2.0
1.46
2.09
u/field
0.55
13
100
14
156
0.90
0.10
1.0
1.1
—
—
—
0
0
21
227
0.92
0.09
1.0
1.1
—
—
—
0
0
6
55
1.09
0.08
2.3
1.5
—
—
—
0
0
6
58
1.03
0.08
6.0
4.9
—
—
—
0
0
5
64
0.78
0.08
1.0
1.1
—
—
—
0
0
24
224
1.07
0.08
1.8
1.3
75.00
72.59
%
—
5
22
8
77
1.04
0.07
1.1
1.1
—
—
—
0
0
16
148
1.08
0.06
2.1
2.2
0.67
1.37
nmol/l
3.30
11
119
25
238
1.05
0.04
1.1
1.2
1.44
1.54
g/l
1.49
25
238
225
2223
1.01
0.04
3.1
2.4
—
—
—
0
0
17
177
0.96
0.01
2.5
2.9
—
—
—
0
0
14
142
0.98
0.00
1.4
1.3
—
—
—
0
0
19
190
1.00
0.00
1.1
1.2
—
—
—
0
0
26
258
1.01
0.00
1.2
1.2
—
—
—
0
0
18
185
0.97
0.00
5.7
7.5
—
—
—
0
0
33
332
0.99
0.00
1.6
1.6
5.79
5.71
mmol/l
0.10
28
274
18
181
0.99
0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.6
1.6
120.98
196.11
mu/l
—
5
46
8
85
0.94
-0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
77
0.91
-0.00
2.0
1.5
—
—
—
0
0
6
66
0.91
-0.00
1.0
4.7
—
4.40
—
0
17
0
5
0.00
-0.00
0.0
1.0
—
1.43
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
13.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
277.50
—
0
6
0
6
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1258.00
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
11.67
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint L12_ACNE and mortality.

Females

Parameter HR [95% CI] p-value
L12_ACNE 2.128 [1.75, 2.59] < 0.001
Birth year 0.996 [0.99, 1.0] 0.347

During the follow-up period (1.1.1998 — 31.12.2019), 306 out of 13469 females with L12_ACNE died.

Males

Parameter HR [95% CI] p-value
L12_ACNE 1.88 [1.62, 2.18] < 0.001
Birth year 0.991 [0.98, 1.0] 0.055

During the follow-up period (1.1.1998 — 31.12.2019), 599 out of 16909 males with L12_ACNE died.

Mortality risk

Mortality risk for people of age

years, who have L12_ACNE.

N-year risk Females Males
1 0.146% 0.335%
5 1.172% 2.19%
10 3.024% 5.676%
15 6.046% 10.808%
20 10.594% 18.722%

Relationships between endpoints

Index endpoint: L12_ACNE – Acne

GWS hits: 11

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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