This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Hypothyroidism, levothyroxine purchases
DOID EFO MESH SNOMED Endpoint Browser
HYPOTHY_LEVOTHY
hypothyroidism: Abnormally low levels of thyroid hormone.
Endpoint definition
↥
FinnGen phenotype data
429209 individuals
Apply sex-specific rule None
429209
Check conditions None
429209
Check pre-conditions, main-only, mode, registry filters
Medicine purchases: ATC
H03AA01
1 out of 7 registries used, show all original rules.
54077
Check minimum number of events
Min. number of events
3
54077
Include endpoints None
54077
Remove individuals based on genotype QC
52222
HYPOTHY_LEVOTHY
Control definitions
Control exclude
E4_MALNUTRITION, E4_DIABETES, I9_CVD, C3_CANCER, MENINGITIS, ENCEPHALITIS, HYPOTHYROIDISM, D3_ANAEMIA, F5_ALLANXIOUS, F5_MOOD, F5_SCHIZO, F5_BEHEMOCHILD, F5_UNSMENDIS, ANOSMIA, ANTIDEPRESSANTS
Extra metadata
First used in FinnGen datafreeze
DF3
Not enough data for upset plot.
Or the full data table
Similar endpoints
↥List of similar endpoints to
Hypothyroidism, levothyroxine purchases
based on the number of shared cases.
Broader endpoints:
- Hypothyroidism and >3 levothyroxin purchases
- Hypothyroidism, other/unspecified
- Hypothyroidism (congenital or acquired)
- Disorders of the thyroid gland
- Used for control exclusion in common control thyroid runs
Narrower endpoints:
Summary Statistics
↥Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 52222 | 41726 | 10496 |
| Unadjusted prevalence (%) | 12.68 | 18.12 | 5.78 |
| Mean age at first event (years) | 51.58 | 49.87 | 58.38 |
Mortality
Not a core endpoint, no data to show.
Age distribution of first events
Year distribution of first events
Cumulative Incidence
Not a core endpoint, no data to show.
Correlations
↥
Index endpoint: HYPOTHY_LEVOTHY – Hypothyroidism, levothyroxine purchases
GWS hits:
Survival analyses between endpoints
↥Not a core endpoint, no data to show.
Drugs most likely to be purchased after Hypothyroidism, levothyroxine purchases
↥Endpoint not on priority list, no data to show.