Meningitis

MENINGITIS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

None

0 out of 7 registries used, show all original rules.

0

4. Check minimum number of events

None

0

5. Include endpoints

2005

6. Filter based on genotype QC (FinnGen only)

1944

Control definitions (FinnGen only)

Control exclude
AB1_VIRAL_CNS

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No data for upset plot.

No data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 18175 8439 9598
Only index persons 14933 7258 7675
Unadjusted period prevalence (%)
Whole population 0.25 0.24 0.27
Only index persons 0.28 0.27 0.29
Median age at first event (years)
Whole population 29.98 32.14 27.70
Only index persons 26.99 29.97 24.16

-FinnGen-

Key figures

All Female Male
Number of individuals 1944 1100 844
Unadjusted period prevalence (%) 0.39 0.39 0.39
Median age at first event (years) 34.80 33.69 36.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2005
Matched controls
20045
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
32099
ICD-8 Finland
Meningitis, With no organism specified as cause
+∞
307.7
370
*
G03.9
ICD-10 Finland
Meningitis, unspecified
2665.4
307.7
446
*
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
3113.9
298.4
281
*
TAB00
NOMESCO Finland
Lumbar puncture
9.7
267.1
339
410
32088
ICD-8 Finland
Meningitis, Alia definita
+∞
212.3
200
*
A87.9
ICD-10 Finland
Viral meningitis, unspecified
+∞
205.8
194
*
32000
ICD-8 Finland
Meningitis, H. influenzae
+∞
118.9
113
*
G01*A69.2
ICD-10 Finland
Meningitis (in) Lyme disease
+∞
112.6
107
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.1
99.5
304
830
G00.1
ICD-10 Finland
Pneumococcal meningitis
+∞
98.8
94
*
AA1AD
NOMESCO Finland
CT of head and brain
2.8
94.7
685
3153
G02.0*B00.3
ICD-10 Finland
Herpesviral meningitis
+∞
93.5
89
*
R51.80
ICD-10 Finland
Headache
3.0
89.9
492
1943
3229X
ICD-9 Finland
Meningitis of unspecified cause, Meningitis, unspecified
+∞
89.2
85
*
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
40.2
83.6
51
13
AAF00
NOMESCO Finland
Ventriculostomy
19.0
74.5
59
32
A86
ICD-10 Finland
Unspecified viral encephalitis
+∞
66.0
63
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.4
62.0
126
245
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
14.4
52.8
48
34
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
9.2
48.2
59
66
G01*A39.0
ICD-10 Finland
Meningococcal meningitis
+∞
43.9
42
*
R50.9
ICD-10 Finland
Fever, unspecified
2.4
43.4
369
1754
G03.8
ICD-10 Finland
Meningitis due to other specified causes
+∞
42.9
41
*
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
15.7
42.6
37
24
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
42.2
365
1746
G03.0
ICD-10 Finland
Nonpyogenic meningitis
+∞
41.8
40
*
N03AX14
ATC
levetiracetam; systemic
4.7
40.6
97
216
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.3
37.0
145
460
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.6
36.2
235
983
G00.8
ICD-10 Finland
Other bacterial meningitis
+∞
35.5
34
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
33.8
330
1649
G91.0
ICD-10 Finland
Communicating hydrocephalus
10.2
33.6
38
38
G00.3
ICD-10 Finland
Staphylococcal meningitis
+∞
33.4
32
*
G00.2
ICD-10 Finland
Streptococcal meningitis
+∞
32.4
31
*
G02.0*B02.1
ICD-10 Finland
Zoster meningitis
+∞
31.3
30
*
R51
ICD-10 Finland
Headache
2.9
31.1
154
559
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
7.5
30.6
44
60
XA800
NOMESCO Finland
Neuropsychological investigation
3.3
30.5
120
381
G03.1
ICD-10 Finland
Chronic meningitis
+∞
29.2
28
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
28.8
868
6198
G02.0*B01.0
ICD-10 Finland
Varicella meningitis
+∞
28.2
27
*
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
6.3
27.9
47
76
G51.0
ICD-10 Finland
Bell palsy
4.0
27.0
79
206
J05AB11
ATC
valaciclovir; oral
2.0
26.9
311
1648
N71
ICPC
Meningitis/encephalitis
274.6
26.8
27
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
28.2
26.7
36
13
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
26.0
444
2680
A69.2
ICD-10 Finland
Lyme disease
2.8
25.9
139
526
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.4
25.4
92
277
0499X
ICD-9 Finland
Other non-arthropod-borne viral diseases of central nervous system, Unspecified non-arthropod-borne viral diseases of central nervous system
+∞
25.0
24
*
3209X
ICD-9 Finland
Bacterial meningitis, Meningitis due to unspecified bacterium
+∞
25.0
24
*
G01*A32.1
ICD-10 Finland
Listerial meningitis
+∞
25.0
24
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
23.5
187
853
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.1
23.3
64
159
N03AX12
ATC
[U] gabapentin; oral
1.9
22.9
338
1941
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.4
22.8
57
132
N03AX16
ATC
[U] pregabalin
1.8
22.7
458
2893
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.3
22.2
184
854
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
6.0
22.2
39
66
G02.0
ICD-10 Finland
Meningitis in viral diseases classified elsewhere
+∞
21.9
21
*
N02AX02
ATC
tramadol; systemic, rectal
1.6
21.5
815
6034
H02AB06
ATC
prednisolone; systemic
1.6
21.4
900
6827
N03AX18
ATC
lacosamide; systemic
7.6
21.2
30
40
32010
ICD-8 Finland
Meningitis, Pneumococcus
+∞
20.9
20
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
20.0
298
1713
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
36.1
19.8
25
7
A87.8
ICD-10 Finland
Other viral meningitis
+∞
19.8
19
*
G02.0*A87.0
ICD-10 Finland
Enteroviral meningitis
+∞
19.8
19
*
G01
ICD-10 Finland
Meningitis in bacterial diseases classified elsewhere
+∞
19.8
19
*
R42
ICD-10 Finland
Dizziness and giddiness
1.7
19.5
409
2598
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
4.3
19.5
50
118
5AB01, ,
NOMESCO Finland
40.5
19.5
24
6
WX882
NOMESCO Finland
High dependency care
3.4
19.2
71
217
N03AF02
ATC
oxcarbazepine; oral
3.1
19.2
82
274
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
5.6
19.2
36
65
G03.2
ICD-10 Finland
Benign recurrent meningitis [Mollaret]
+∞
18.8
18
*
G00.0
ICD-10 Finland
Haemophilus meningitis
+∞
18.8
18
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.9
18.6
54
140
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
18.5
305
1805
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
4.7
18.5
42
90
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
18.5
95
352
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
16.3
18.3
29
18
04599
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Aseptic meningitis, unspecified
+∞
17.7
17
*
G05.1*B00.4
ICD-10 Finland
Herpesviral meningoencephalitis
95.9
17.6
19
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
17.3
434
2882
G44.2
ICD-10 Finland
Tension-type headache
1.8
17.2
278
1633
N03AB02
ATC
phenytoin; systemic
5.1
17.2
36
72
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
17.1
686
5076
SPAT1255
SPAT
Intravenous administration of medicine
2.3
17.1
136
619
G91.1
ICD-10 Finland
Obstructive hydrocephalus
13.4
17.0
29
22
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.3
16.5
42
99
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
16.3
195
1038
PA2AD
NOMESCO Finland
CT angiography of brain
5.9
16.2
29
50
J05AB01
ATC
aciclovir; systemic
1.6
16.2
417
2782
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
16.0
423
2839
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
15.9
369
2398
3200A
ICD-9 Finland
Bacterial meningitis, Haemophilus meningitis
+∞
15.6
15
*
B00.3
ICD-10 Finland
Herpesviral meningitis
+∞
15.6
15
*
3201A
ICD-9 Finland
Bacterial meningitis, Pneumococcal meningitis
+∞
15.6
15
*
ZXD05
NOMESCO Finland
Urgent procedure
1.5
15.5
573
4150
A02BC02
ATC
pantoprazole; systemic
1.5
15.1
1246
10562
A41.9
ICD-10 Finland
Sepsis, unspecified
2.8
15.1
74
267
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
23.6
15.1
21
9
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
15.0
202
1119
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.2
14.8
57
179
ZXC95
NOMESCO Finland
Use of surgical navigator
4.3
14.8
38
90
J01DB01
ATC
cefalexin; oral
1.6
14.8
1598
14292
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
25.2
14.7
20
8
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
4.2
14.6
38
91
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
6.6
14.5
23
35
N05CF01
ATC
zopiclone; oral
1.5
14.4
568
4158
N03AG01
ATC
valproic acid; systemic, rectal
2.2
14.4
129
617
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.3
14.4
53
162
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
14.4
96
405
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.4
14.3
99
425
J01FF01
ATC
clindamycin; systemic
1.5
14.1
499
3570
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.7
14.1
78
301
H47.1
ICD-10 Finland
Papilloedema, unspecified
6.1
13.9
24
40
H02AB07
ATC
prednisone; oral
1.7
13.8
252
1531
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
13.7
119
562
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
13.7
348
2306
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.5
13.6
87
360
ZX120
NOMESCO Finland
Intravenous
1.9
13.6
176
963
A39.0
ICD-10 Finland
Meningococcal meningitis
140.9
13.5
14
*
WX730
NOMESCO Finland
Conventional respirator
4.2
13.4
35
84
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
4.6
13.3
31
68
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
13.2
219
1294
N06AA09
ATC
amitriptyline; systemic
1.9
13.1
174
960
N01
ICPC
Headache
1.8
12.9
216
1279
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
12.9
204
1188
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
12.9
467
3348
J01AA02
ATC
doxycycline; systemic
1.5
12.7
1446
12798
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
12.6
782
6215
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
32.2
12.6
16
5
A87.0
ICD-10 Finland
Enteroviral meningitis
+∞
12.5
12
*
L04AX01
ATC
azathioprine; systemic
2.4
12.5
89
387
XCK00
NOMESCO Finland
Perimetry
2.2
12.4
107
504
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
12.3
232
1422
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.5
12.3
41
118
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
4.3
12.2
31
73
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
12.2
132
679
N03AF01
ATC
carbamazepine; oral, rectal
2.2
12.0
101
471
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.9
11.9
151
820
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
11.9
978
8133
N03AE01
ATC
clonazepam; systemic
2.1
11.6
107
518
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
11.6
148
805
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
11.4
108
528
TKC20
NOMESCO Finland
Catheterisation of bladder
2.0
11.3
115
578
N73
ICPC
Neurological infection other
35.2
11.3
14
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
11.2
625
4846
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
11.1
411
2947
G40.10
ICD-10 Finland
Simple partial seizures
5.3
11.1
22
42
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
11.0
126
661
J01EA01
ATC
trimethoprim; systemic
1.5
11.0
433
3146
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.3
10.9
80
353
WX872
NOMESCO Finland
Intensive care
2.2
10.9
95
451
S06.0
ICD-10 Finland
Concussion
1.7
10.7
197
1199
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
3.1
10.6
44
145
A32.7
ICD-10 Finland
Listerial sepsis
60.3
10.6
12
*
G09
ICD-10 Finland
Sequelae of inflammatory diseases of central nervous system
60.3
10.6
12
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.6
10.5
58
224
AAA10
NOMESCO Finland
Biopsy through craniotomy
110.6
10.4
11
*
B34.9
ICD-10 Finland
Viral infection, unspecified
2.6
10.4
61
243
N05BA04
ATC
oxazepam; oral
1.5
10.4
450
3326
AAF15
NOMESCO Finland
Ventriculoatrial shunt
16.1
10.3
16
10
H53.2
ICD-10 Finland
Diplopia
2.4
10.3
69
293
J01MA02
ATC
ciprofloxacin; systemic
1.4
10.2
659
5224
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
10.2
196
1206
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
10.1
443
3280
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
2.8
10.1
49
177
N30.0
ICD-10 Finland
Acute cystitis
1.6
9.8
263
1756
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.1
9.8
92
449
WX704
NOMESCO Finland
Intubation
1.8
9.8
145
828
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.7
9.7
175
1057
B00.4
ICD-10 Finland
Herpesviral encephalitis
55.3
9.6
11
*
N02BE01
ATC
paracetamol; systemic, rectal
1.5
9.6
1676
15517
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
9.6
800
6593
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
9.6
240
1579
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
4.0
9.5
26
65
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.2
9.4
75
343
ZZC00
NOMESCO Finland
Graft of fascia
30.2
9.4
12
*
G01*A17.0
ICD-10 Finland
Tuberculous meningitis
+∞
9.4
9
*
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
5.2
9.4
19
37
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
10.7
9.3
17
16
J01DA01
ATC
[U] cefalexin
1.3
9.2
1123
9767
Z3231
NOMESCO Finland
Registered nurse
1.4
9.2
460
3479
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
9.2
479
3652
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
9.2
520
4022
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
9.1
212
1368
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
4.6
9.1
21
46
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.2
9.1
75
349
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
3.8
9.1
27
72
R11
ICD-10 Finland
Nausea and vomiting
1.7
9.0
152
902
AAK00
NOMESCO Finland
Cranioplasty
18.7
8.9
13
7
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
24.1
8.9
12
5
79199
ICD-8 Finland
Headache
3.6
8.8
28
78
J01FA10
ATC
azithromycin; systemic
1.3
8.8
1059
9166
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
2.2
8.8
74
347
A06AD11
ATC
lactulose; oral
1.6
8.7
224
1481
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
2.4
8.7
56
234
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
8.6
506
3928
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
8.6
170
1052
UKC02
NOMESCO Finland
Cystoscopy
1.6
8.6
233
1558
N03AX09
ATC
lamotrigine; oral
2.0
8.6
95
493
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
16.3
8.5
13
8
6BA02, ,
NOMESCO Finland
10.1
8.5
16
16
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
8.5
110
602
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.3
8.5
65
293
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
3.9
8.4
24
62
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
90.4
8.4
9
*
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
3.4
8.4
29
86
G05.1
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
+∞
8.3
8
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
8.2
315
2265
Z2445
NOMESCO Finland
Psychologist
2.1
8.2
75
363
L04AA06
ATC
mycophenolic acid; systemic
2.9
8.2
38
134
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
8.2
619
4993
ZZF00
NOMESCO Finland
Graft of adipose tissue
4.2
8.2
21
50
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
4.4
8.1
20
46
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.9
8.1
102
554
J02AC01
ATC
fluconazole; systemic
1.3
8.1
672
5498
ABE50
NOMESCO Finland
Occipitocervical decompression
17.2
8.1
12
7
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.0
8.1
81
407
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.0
690
5672
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
8.0
240
1644
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
8.0
361
2679
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
7.9
99
536
P01BA02
ATC
hydroxychloroquine; oral
1.7
7.9
136
811
R40.2
ICD-10 Finland
Coma, unspecified
4.3
7.9
20
47
G43.9
ICD-10 Finland
Migraine, unspecified
1.8
7.9
108
602
J01MA14
ATC
moxifloxacin; systemic
1.7
7.9
149
912
R03AC02
ATC
salbutamol; inhalant
1.3
7.9
991
8578
M50.9
ICD-10 Finland
Cervical disc disorder, unspecified
4.5
7.9
19
43
T78.4
ICD-10 Finland
Allergy, unspecified
2.0
7.9
84
431
G63.0*A69.2
ICD-10 Finland
Polyneuropathy (in) Lyme disease
13.1
7.9
13
10
G06.0
ICD-10 Finland
Intracranial abscess and granuloma
13.1
7.9
13
10
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.2
7.9
61
277
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
3.6
7.9
25
70
N06AX11
ATC
mirtazapine; oral
1.3
7.8
584
4697
S18
ICPC
Laceration/cut
1.3
7.8
761
6358
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
10.8
7.8
14
13
R53
ICD-10 Finland
Malaise and fatigue
1.4
7.7
400
3035
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
2.1
7.7
75
372
B02.1
ICD-10 Finland
Zoster meningitis
45.1
7.7
9
*
R4150
NOMESCO Finland
Neuropsychological rehabilitation
3.9
7.7
22
57
AA1AA
NOMESCO Finland
Head X-ray examination
3.9
7.7
22
57
M01AE02
ATC
naproxen; oral, rectal
1.3
7.7
1019
8874
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
3.5
7.7
26
76
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.9
7.7
91
485
Q07.0
ICD-10 Finland
Arnold-Chiari syndrome
10.1
7.5
14
14
J01CA04
ATC
amoxicillin; systemic
1.4
7.5
1533
14142
A40.8
ICD-10 Finland
Other streptococcal sepsis
4.3
7.5
19
45
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
7.5
618
5042
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
7.4
183
1198
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
4.4
7.4
18
41
B94.1
ICD-10 Finland
Sequelae of viral encephalitis
80.4
7.4
8
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
7.4
314
2300
A02BC01
ATC
omeprazole; systemic
1.4
7.4
433
3351
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
13.4
7.4
12
9
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
4.0
7.3
20
50
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
2.8
7.3
35
126
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
7.3
153
963
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.5
7.3
246
1724
B94.80
ICD-10 Finland
Late effects of bacterial meningitis
+∞
7.3
7
*
3202A
ICD-9 Finland
Bacterial meningitis, Streptococcal meningitis
+∞
7.3
7
*
A32.1
ICD-10 Finland
Listerial meningitis and meningoencephalitis
+∞
7.3
7
*
A84.8
ICD-10 Finland
Other tick-borne viral encephalitis
+∞
7.3
7
*
UDC00
NOMESCO Finland
Ear microscopy
1.7
7.3
124
739
183
Kela drug reimbursment
Lamotrigin and topiramate
3.8
7.3
21
55
DPA30
NOMESCO Finland
Sphenotomy
4.3
7.2
18
42
J01MA01
ATC
ofloxacin; systemic
1.7
7.2
129
779
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.9
7.2
84
446
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
2.9
7.2
32
111
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
3.2
7.1
27
85
101
Kela drug reimbursment
Anterior pituitary hypofunction
3.8
7.1
21
56
N06AX21
ATC
duloxetine; oral
1.5
7.1
204
1384
N03AX11
ATC
topiramate; oral
2.4
7.0
48
207
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
3.0
6.9
29
97
N05BA01
ATC
diazepam; systemic, rectal
1.5
6.9
215
1482
D33.30
ICD-10 Finland
Acoustic neuroma
5.5
6.9
19
35
N06AX16
ATC
venlafaxine; oral
1.5
6.9
253
1802
F05.9
ICD-10 Finland
Delirium, unspecified
2.8
6.9
33
119
3451A
ICD-9 Finland
Epilepsy, Generalised convulsive epilepsy
13.8
6.9
11
8
N07BA03
ATC
varenicline; oral
1.9
6.9
90
496
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
3.4
6.8
24
72
PA2KT
NOMESCO Finland
Endovascular closure of brain aneurysm
9.3
6.8
13
14
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
16.7
6.7
10
6
H02AB04
ATC
methylprednisolone; systemic
1.5
6.7
230
1616
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
2.4
6.7
45
192
R41.0
ICD-10 Finland
Disorientation, unspecified
2.4
6.7
45
192
B01AA03
ATC
warfarin; systemic
1.5
6.7
252
1803
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
6.7
218
1517
R52.2
ICD-10 Finland
Other chronic pain
2.0
6.6
68
345
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.0
6.6
70
359
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
3.1
6.6
26
84
G91.8
ICD-10 Finland
Other hydrocephalus
12.3
6.6
11
9
N05AH04
ATC
quetiapine; oral
1.4
6.6
307
2286
WX892
NOMESCO Finland
Monitored bed care
1.7
6.5
121
738
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.0
6.5
69
354
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
3.8
6.5
19
50
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.8
6.5
91
512
N02CA01
ATC
dihydroergotamine; nasal, systemic
6.9
6.5
15
22
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
6.5
214
1493
ZXA05
NOMESCO Finland
Left side
1.4
6.5
380
2937
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
6.4
285
2102
M03BX02
ATC
tizanidine; oral
1.3
6.4
1121
10010
N02AA05
ATC
oxycodone; systemic
1.4
6.4
255
1845
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
6.4
291
2156
ZXA00
NOMESCO Finland
Right side
1.3
6.4
413
3239
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.4
6.4
42
178
G44.8
ICD-10 Finland
Other specified headache syndromes
2.8
6.4
31
113
N28
ICPC
Limited function/disability (N)
2.9
6.4
29
102
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.6
6.4
140
893
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.3
6.4
47
210
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
2.7
6.3
32
119
J45.8
ICD-10 Finland
Mixed asthma
2.2
6.3
51
236
A03
ICPC
Fever
1.4
6.3
286
2117
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.7
6.3
116
708
G94.2
ICD-10 Finland
Hydrocephalus in other diseases classified elsewhere
+∞
6.3
6
*
A89
ICD-10 Finland
Unspecified viral infection of central nervous system
+∞
6.3
6
*
SPAT1229
SPAT
Assessment of need for aid
1.7
6.3
108
647
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
6.2
396
3097
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.9
6.2
76
410
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.2
6.2
51
238
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.4
6.2
40
168
R03BA05
ATC
fluticasone; inhalant
1.4
6.2
302
2263
R4110
NOMESCO Finland
Physiotherapy
1.3
6.2
446
3552
J01MA12
ATC
levofloxacin; systemic
1.4
6.2
288
2143
N99
ICPC
Neurological disease other
3.1
6.2
24
77
SPAT1153
SPAT
Removal of sutures
1.3
6.2
493
3986
M54.5
ICD-10 Finland
Low back pain
1.3
6.1
621
5178
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
3.4
6.1
21
62
R60.0
ICD-10 Finland
Localized oedema
1.5
6.1
176
1194
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.1
6.1
53
253
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.8
6.1
91
523
120
Kela drug reimbursment
Hypogammaglobulinaemia
12.6
6.1
10
8
I60.6
ICD-10 Finland
Subarachnoid haemorrhage from other intracranial arteries
12.6
6.1
10
8
J06BA01
ATC
immunoglobulins, normal human, for extravascular adm.; systemic
12.6
6.1
10
8
J01FA06
ATC
roxithromycin; oral
1.3
6.1
668
5628
X58
ICD-10 Finland
Exposure to other specified factors
1.4
6.1
250
1820
R01AD08
ATC
fluticasone; nasal
1.3
6.1
486
3929
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
8.6
6.1
12
14
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.6
6.0
19
53
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
2.5
6.0
35
140
N05CD07
ATC
temazepam; oral
1.5
6.0
170
1148
B00.9
ICD-10 Finland
Herpesviral infection, unspecified
5.2
6.0
17
33

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
340
321
12.55
321.50
1.9
1.4
—
—
—
0
0
372
353
12.71
307.65
1.8
1.2
3.28
3.75
mmol/l
7.03
351
331
295
135
25.44
307.65
2.1
1.7
—
—
—
0
0
394
402
11.95
307.65
1.9
1.2
1069.91
493.47
mg/l
15.92
382
379
234
161
16.32
266.01
1.7
1.5
—
—
—
0
0
319
360
10.35
264.80
1.9
1.4
358.50
23.97
e6/l
4.22
256
279
319
360
10.35
264.80
2.0
1.5
786.78
756.42
e6/l
0.02
259
294
171
116
16.02
194.95
2.1
1.2
3.51
1.91
mmol/l
7.30
165
110
173
175
10.72
153.69
1.3
1.0
72.55
—
au/ml
—
10
0
161
159
10.92
145.34
1.1
1.0
—
—
—
0
0
111
59
19.85
142.17
1.2
1.1
524.11
37.67
ng/l
—
62
9
152
164
9.94
128.60
1.6
1.6
—
—
—
0
0
89
76
12.20
88.05
2.0
1.1
53.33
55.67
%
—
51
6
56
22
26.15
80.58
2.0
1.2
54.98
38.00
%
—
48
6
311
1131
3.07
64.05
2.9
2.4
31.79
25.23
au/ml
0.43
18
103
291
1029
3.14
62.84
1.6
1.3
58.75
44.63
au/ml
0.50
19
63
103
193
5.57
52.68
5.3
6.7
10.38
11.40
mg/l
1.21
94
174
691
4000
2.11
50.84
4.7
4.2
—
—
—
0
0
56
80
7.17
37.37
1.2
1.2
—
—
—
0
0
265
1235
2.32
32.02
3.7
2.7
10.09
10.56
g/l
1.12
254
1127
67
139
4.95
30.54
1.3
1.1
81.05
41.68
mg/l
3.62
59
109
681
4558
1.75
28.55
2.5
2.1
152.93
242.31
u/l
2.16
656
4293
61
134
4.66
25.99
1.1
1.1
485.72
275.72
mg/l
2.25
53
112
397
2316
1.89
25.91
2.1
2.1
29.23
29.76
s
0.77
387
2242
1061
8182
1.63
24.81
7.0
6.1
10.34
11.35
umol/l
2.18
1010
7780
60
141
4.35
23.52
1.9
2.3
1.35
1.29
e9/l
0.16
52
125
915
6892
1.60
22.91
14.1
13.3
1.24
1.22
inr
0.19
269
2054
1046
8137
1.60
22.82
7.5
5.8
0.58
0.57
e9/l
0.52
933
7096
49
100
5.00
22.79
1.8
2.5
0.21
0.21
e9/l
0.05
40
86
1150
9160
1.60
22.61
5.8
4.8
6.59
6.64
mmol/l
0.38
1092
8549
1046
8149
1.59
22.59
7.5
5.9
0.04
0.04
e9/l
0.56
932
7102
1073
8428
1.59
22.23
7.7
6.1
0.20
0.19
e9/l
0.58
959
7447
49
104
4.80
21.78
1.8
2.5
524.93
586.06
e6/l
0.24
40
87
1065
8389
1.57
21.50
7.5
5.9
2.07
1.97
e9/l
0.56
970
7476
33
49
6.83
21.25
1.5
1.3
—
—
—
0
0
120
475
2.62
20.48
2.8
1.5
0.22
0.24
g/l
1.33
110
448
980
7639
1.55
20.25
7.8
6.0
2.85
2.86
%
0.03
927
7181
969
7538
1.55
20.19
8.1
6.7
1.21
1.21
mmol/l
1.62
833
6440
1009
7923
1.55
20.13
7.9
6.1
28.61
28.36
%
0.28
957
7479
49
113
4.42
19.70
1.7
1.5
—
—
—
0
0
25
30
8.42
19.27
1.1
1.0
12.14
8.15
mg/g
0.91
25
30
976
7663
1.53
19.10
8.4
6.3
—
—
—
0
0
1154
9398
1.54
19.03
10.6
8.9
4.21
4.05
e9/l
1.38
1037
8245
947
7391
1.53
19.03
7.9
6.1
0.66
0.68
%
0.61
891
6937
977
7682
1.53
18.93
8.2
6.3
8.30
8.49
%
1.05
923
7233
887
6837
1.53
18.81
7.3
6.1
1.20
1.21
mmol/l
2.50
822
6254
357
2208
1.75
18.67
1.9
2.0
—
—
—
0
0
989
7818
1.52
18.55
7.5
5.8
56.43
56.87
%
0.54
936
7376
119
495
2.49
18.34
2.9
1.5
1.18
1.19
g/l
0.12
109
464
189
976
2.03
17.27
2.1
1.8
1.35
1.37
g/l
0.03
172
898
852
6598
1.51
17.18
5.7
4.9
35.48
35.99
g/l
1.71
804
6180
670
4955
1.53
16.69
2.7
2.5
57.45
74.94
u/l
0.50
624
4598
757
5753
1.51
16.53
3.5
3.4
23.12
46.61
ng/l
2.69
493
3742
53
161
3.35
14.53
1.5
1.3
—
—
—
0
0
1405
12295
1.48
13.75
9.5
7.3
77.48
77.31
u/l
0.05
1354
11612
66
238
2.83
13.54
1.3
1.4
76.36
65.40
mmol/l
0.90
50
199
269
1679
1.69
13.33
8.9
8.6
1.17
1.16
mmol/l
0.03
222
1329
1214
10391
1.43
12.95
5.9
4.2
2958.95
1943.41
e6/l
0.16
21
147
117
565
2.14
12.77
2.4
2.1
1.02
1.80
ug/l
0.70
105
499
50
160
3.18
12.65
1.6
1.3
2.53
2.97
g/l
1.41
37
112
50
160
3.18
12.65
1.6
1.3
0.31
0.37
g/l
0.94
37
112
50
160
3.18
12.65
1.6
1.3
5.91
6.79
g/l
1.15
37
114
265
1681
1.66
12.31
9.0
8.6
12.74
12.35
kpa
0.61
254
1609
265
1681
1.66
12.31
9.0
8.6
5.10
5.12
kpa
0.15
254
1607
1355
11884
1.43
12.24
5.0
4.0
11.94
11.21
mm/h
1.20
1293
11070
287
1873
1.62
11.90
2.0
1.7
—
—
—
0
0
361
2486
1.55
11.90
3.7
3.6
0.82
0.82
mmol/l
0.23
344
2348
239
1498
1.68
11.60
9.4
9.1
96.01
95.66
%
0.32
230
1445
67
265
2.58
11.54
1.9
1.7
0.68
0.85
g/l
0.61
51
204
533
4001
1.45
11.49
4.4
3.9
92.51
91.79
%
0.29
522
3895
59
220
2.73
11.42
1.2
1.2
—
—
—
0
0
300
2007
1.58
11.18
6.6
5.9
1.02
1.04
mmol/l
0.81
288
1862
215
1339
1.68
10.68
7.9
7.8
8.09
9.04
mmol/l
1.50
208
1277
94
449
2.15
10.59
2.1
2.2
10.56
11.24
mg/l
0.39
89
416
31
83
3.78
10.32
1.3
1.1
1830.84
1636.93
miu/ml
0.33
31
83
220
1397
1.65
10.13
10.3
9.5
120.02
122.75
g/l
1.15
213
1359
579
4498
1.40
10.10
3.6
2.9
—
—
—
0
0
21
42
5.04
10.04
1.4
2.0
216.36
208.18
e6/l
0.05
11
22
396
2880
1.47
9.89
3.6
3.5
189.25
468.68
ng/l
2.51
272
2123
323
2266
1.51
9.63
1.4
1.3
704.23
507.72
titre
0.83
71
469
46
166
2.81
9.51
1.6
1.5
285.11
281.31
mosm/kgh2o
0.55
37
124
1245
11002
1.35
9.16
5.6
4.1
—
—
—
0
0
235
1554
1.58
9.14
2.7
2.1
358.77
371.42
nmol/l
0.38
220
1425
14
9
15.64
9.03
1.8
1.0
—
—
—
0
0
157
944
1.72
8.88
10.6
7.8
25.08
24.51
mmol/l
1.37
148
898
137
793
1.78
8.85
11.2
12.2
—
—
—
0
0
437
3309
1.41
8.65
1.6
1.5
2.30
2.36
g/l
0.24
296
2066
405
3047
1.41
8.28
3.6
2.8
535.01
543.20
mosm/kgh2o
0.31
366
2622
96
508
1.93
8.24
2.3
2.4
636.85
450.48
ug/l
0.23
87
478
22
55
4.03
8.07
1.7
1.7
—
—
—
0
0
350
2577
1.43
8.06
3.1
2.7
1.19
1.25
e6/l
0.07
188
1443
780
6523
1.32
8.04
2.6
2.3
76.78
75.96
nmol/l
0.36
707
5902
11
5
22.10
8.01
1.1
1.0
—
—
—
0
0
91
478
1.95
7.99
9.5
8.0
1.29
1.29
mmol/l
0.01
79
420
516
4064
1.36
7.97
7.1
6.6
—
—
—
0
0
87
451
1.97
7.93
1.5
1.2
42.30
28.25
u/ml
—
9
25
474
3689
1.37
7.88
1.7
1.8
1.11
1.07
mg/l
0.13
360
2772
1267
11351
1.31
7.77
3.7
3.1
52.37
47.51
u/l
1.03
1212
10682
462
3599
1.37
7.60
4.2
3.4
—
—
—
0
0
612
4976
1.33
7.59
2.6
2.3
—
—
—
0
0
576
4646
1.34
7.53
4.2
3.1
26.16
73.33
e6/l
2.42
455
3549
155
974
1.64
7.44
8.2
5.7
—
—
—
0
0
81
420
1.97
7.40
1.5
1.2
5.28
9.71
u/ml
0.49
17
68
663
5479
1.31
7.26
4.9
3.6
47.85
97.38
e6/l
1.95
478
3827
530
4244
1.34
7.24
4.0
3.0
0.24
0.43
e6/l
2.24
409
3192
726
6091
1.30
7.06
2.0
1.9
98.93
95.66
pmol/l
0.83
376
3240
658
5450
1.31
7.04
3.7
3.3
32.83
32.60
u/l
0.05
626
5190
79
415
1.94
6.97
1.5
1.2
8.28
2.56
u/ml
0.69
11
41
201
1367
1.52
6.89
3.9
3.7
1.67
1.95
mmol/l
0.56
181
1128
14
17
8.28
6.82
1.1
2.5
—
—
—
0
0
110
648
1.74
6.74
1.4
1.2
0.26
1.06
u/ml
—
9
54
68
344
2.01
6.69
11.1
9.6
10.82
11.31
mmol/l
0.58
61
310
413
3219
1.36
6.69
3.5
2.5
5.66
5.93
e6/l
0.14
383
2893
68
345
2.00
6.64
11.1
9.5
104.87
105.48
mmol/l
0.46
61
311
111
659
1.72
6.62
1.7
1.4
18.76
9.38
u/ml
—
5
20
752
6386
1.28
6.53
4.2
3.2
5.95
5.87
ph
0.33
63
560
909
7907
1.27
6.49
4.5
3.5
0.00
0.00
estimate
0.80
164
1584
322
2424
1.39
6.45
3.4
2.9
2.52
2.57
e6/l
0.04
161
1292
518
6283
0.76
6.39
2.6
2.7
—
—
—
0
0
435
3439
1.34
6.38
4.7
3.7
1.02
1.02
kg/l
1.15
76
484
866
7504
1.27
6.33
2.8
2.5
—
—
—
0
0
210
1467
1.48
6.33
4.4
4.0
—
—
—
0
0
1735
16440
1.41
6.33
19.9
13.0
22.57
22.95
mg/l
0.18
1475
12853
103
607
1.73
6.32
8.6
6.6
0.94
0.90
%
0.54
96
567
103
609
1.73
6.25
8.4
6.6
1.79
1.63
%
0.76
96
570
183
1251
1.51
6.13
8.1
9.2
—
—
—
0
0
911
7984
1.26
5.92
4.5
3.5
0.00
0.01
estimate
1.32
159
1436
182
1254
1.50
5.87
4.3
3.3
—
—
—
0
0
903
7915
1.26
5.83
6.0
4.7
0.00
0.00
estimate
0.50
164
1503
138
904
1.57
5.63
1.3
1.2
—
—
—
0
0
509
4178
1.29
5.61
3.9
3.0
—
—
—
0
0
417
3343
1.31
5.47
2.0
1.9
—
—
—
0
0
169
1165
1.49
5.45
2.4
2.8
68.89
71.54
e9/l
0.30
129
885
165
1133
1.50
5.43
3.2
3.0
6.95
5.55
e9/l
0.24
123
952
171
1185
1.48
5.38
2.6
2.7
66.67
66.88
g/l
0.13
158
1096
219
1597
1.42
5.27
2.6
2.7
1.77
1.78
%
0.03
198
1437
37
163
2.29
5.22
3.7
4.0
—
—
—
0
0
742
6418
1.25
5.22
2.1
2.0
—
—
—
0
0
207
1504
1.42
5.08
2.5
2.4
31.61
71.48
u/l
0.68
181
1283
101
631
1.63
5.04
1.5
2.0
1.63
1.54
g/l
0.37
89
552
54
280
1.95
5.04
1.2
1.1
—
10.10
—
0
18
157
1085
1.48
5.02
1.4
1.3
152.35
226.73
u/ml
0.71
149
1000
31
129
2.42
4.97
1.1
1.2
—
—
—
0
0
337
2656
1.32
4.97
1.9
1.7
1179.13
1190.85
nmol/l
0.09
266
2027
63
349
1.83
4.83
1.5
1.2
21.21
43.19
u/ml
1.11
13
34
109
702
1.58
4.82
2.7
2.5
1.19
1.27
%
0.38
109
697
249
1884
1.37
4.81
1.7
1.5
—
—
—
0
0
183
1314
1.43
4.80
4.6
4.2
0.78
0.99
%
0.64
82
445
461
3805
1.27
4.78
2.6
2.2
—
—
—
0
0
195
1436
1.40
4.45
2.4
2.3
0.22
0.22
g/l
0.25
185
1350
36
169
2.15
4.41
2.3
6.8
7.73
7.00
mmol/l
0.21
24
142
526
4446
1.25
4.41
4.7
3.9
7.39
7.40
ph
1.25
104
857
605
5193
1.24
4.41
3.7
3.4
2.35
2.35
mmol/l
0.71
538
4625
131
898
1.49
4.39
2.9
3.1
125.55
130.62
g/l
1.90
131
877
75
451
1.69
4.37
1.4
1.5
262.28
287.41
ug/g
0.53
43
251
77
467
1.67
4.35
1.1
1.1
—
—
—
0
0
1351
12598
1.22
4.18
4.3
3.9
14.68
14.69
pmol/l
0.06
1241
11573
165
1201
1.41
4.04
4.4
4.1
0.55
0.66
%
0.44
75
382
475
4007
1.24
4.01
2.9
3.0
1235.07
1215.47
ng/l
0.02
405
3373
139
983
1.44
4.00
4.9
3.6
5.15
5.16
kpa
0.02
133
949
107
718
1.52
3.99
5.0
3.7
—
—
—
0
0
236
1824
1.33
3.98
2.7
2.7
6.71
7.84
umol/l
0.55
198
1585
25
106
2.38
3.90
1.1
1.1
—
—
—
0
0
95
628
1.54
3.81
4.7
3.9
24.71
24.85
mmol/l
0.20
88
589
36
180
2.02
3.79
1.4
1.2
—
—
—
0
0
408
3405
1.25
3.78
1.6
1.5
21.78
20.74
nmol/l
0.64
349
2924
169
1251
1.38
3.77
4.7
4.3
0.13
0.12
%
0.05
70
381
484
4119
1.23
3.74
2.8
2.6
1392.97
4951.94
umol/l
2.34
434
3660
494
4214
1.23
3.73
5.1
3.8
0.00
0.00
estimate
1.28
151
1463
39
202
1.95
3.73
1.2
1.6
—
—
—
0
0
257
2030
1.30
3.72
1.7
1.6
—
—
—
0
0
803
7182
1.20
3.71
11.3
9.2
0.00
0.00
e9/l
0.40
658
5902
11
25
4.42
3.62
1.0
1.1
—
—
—
0
0
57
338
1.71
3.56
5.1
3.9
55.21
57.46
%
0.60
57
338
382
3186
1.25
3.55
1.6
1.7
63265747.37
36384437.63
pmol/l
0.24
343
2677
159
1182
1.37
3.47
4.6
4.4
0.07
0.64
%
0.89
61
313
55
326
1.71
3.45
4.7
3.7
3.77
4.17
e9/l
0.61
55
326
1729
16657
1.27
3.44
20.8
14.7
139.47
139.65
mmol/l
2.33
1704
16237
134
973
1.40
3.37
5.1
3.6
7.41
7.41
ph
0.17
16
123
797
7179
1.18
3.29
3.0
2.8
113.29
119.32
ug/l
0.38
743
6682
22
96
2.31
3.26
1.1
1.0
734.14
732.46
ng/l
0.01
14
57
22
96
2.31
3.26
1.1
1.0
229.00
278.48
ng/l
0.38
13
58
68
434
1.59
3.22
3.0
3.3
—
—
—
0
0
136
999
1.39
3.21
3.1
3.3
4.47
4.54
pmol/l
0.31
115
881
45
260
1.75
3.11
4.4
5.5
358.00
373.47
umol/l
0.33
38
227
266
2162
1.27
3.09
2.8
2.4
2.32
2.35
g/l
0.29
255
2010
53
323
1.66
3.03
2.1
2.3
131.53
130.17
g/l
0.11
34
244
55
339
1.64
3.02
1.6
1.4
—
—
—
0
0
85
580
1.49
3.00
7.2
4.7
—
—
—
0
0
1729
16710
1.25
2.99
20.8
14.8
3.96
3.96
mmol/l
0.28
1700
16261
136
1013
1.37
2.97
2.8
2.7
—
—
—
0
0
52
318
1.65
2.95
5.9
3.3
—
—
—
0
0
255
2077
1.26
2.91
2.6
2.4
138.35
126.84
ug/g
0.26
206
1664
447
3862
1.20
2.91
2.3
2.1
2.96
2.93
mg/l
0.10
391
3291
49
297
1.67
2.88
1.7
2.0
4.36
5.24
mmol/24h
0.83
40
262
81
555
1.48
2.82
1.3
1.3
—
—
—
0
0
51
315
1.63
2.80
1.6
1.4
99.86
116.73
u/ml
—
7
64
5
6
8.35
2.75
3.2
2.5
8.46
22.22
mmol/l
—
5
6
5
6
8.35
2.75
1.6
1.0
—
—
—
0
0
17
72
2.37
2.72
1.2
1.2
—
—
—
0
0
266
2201
1.24
2.65
1.2
1.2
—
—
—
0
0
170
1336
1.30
2.60
1.4
1.4
—
—
—
0
0
283
2363
1.23
2.60
2.8
2.4
12.97
13.59
umol/l
0.64
273
2208
38
222
1.73
2.58
3.3
3.3
—
—
—
0
0
51
323
1.59
2.56
2.1
2.9
—
—
—
0
0
12
44
2.74
2.54
1.2
1.1
—
—
—
0
0
215
1746
1.26
2.54
1.6
1.7
—
—
—
0
0
52
332
1.58
2.53
8.3
4.0
2.69
2.55
mmol/l
0.10
27
220
10
31
3.24
2.51
2.4
2.0
—
—
—
0
0
490
4321
1.18
2.50
3.9
3.6
—
—
—
0
0
11
37
2.98
2.48
2.4
3.2
—
—
—
0
0
321
2728
1.21
2.48
1.3
1.3
6.86
11.34
u/ml
1.03
123
1097
244
2016
1.24
2.48
3.0
2.5
22.48
23.43
%
0.40
210
1733
159
1253
1.29
2.40
2.3
2.3
5.91
7.22
ug/l
0.53
134
1122
9
27
3.34
2.39
1.3
1.0
—
—
—
0
0
9
27
3.34
2.39
1.3
1.0
—
—
—
0
0
9
27
3.34
2.39
1.3
1.0
—
—
—
0
0
89
645
1.40
2.35
1.3
1.2
—
—
—
0
0
145
1136
1.30
2.30
4.2
3.9
78.85
83.36
ng/l
0.35
127
1005
29
163
1.79
2.27
1.1
1.1
—
—
—
0
0
95
705
1.36
2.19
1.8
1.8
—
—
—
0
0
52
345
1.52
2.18
1.2
1.2
—
—
—
0
0
70
494
1.43
2.16
2.5
2.4
9.90
10.28
g/l
0.26
62
452
332
2867
1.19
2.16
1.4
1.3
23.95
29.91
iu/ml
0.53
111
935
59
403
1.48
2.15
7.8
3.8
7.41
7.42
ph
0.64
50
357
76
546
1.41
2.13
4.6
3.3
0.23
0.23
g/l
0.07
34
236
24
130
1.86
2.12
1.2
1.5
0.71
1.26
promille
1.40
19
105
58
397
1.47
2.10
2.6
2.3
—
—
—
0
0
34
206
1.66
2.08
2.4
2.5
—
—
—
0
0
32
192
1.68
2.03
1.2
1.2
—
—
—
0
0
8
26
3.08
2.01
2.4
1.7
—
—
—
0
0
87
647
1.36
2.00
1.1
1.1
—
—
—
0
0
223
1869
1.22
2.00
4.6
4.3
32.08
31.71
%
0.17
149
1315
25
141
1.78
1.97
3.4
3.3
—
—
—
0
0
42
273
1.55
1.95
1.5
1.4
—
—
—
0
0
142
1136
1.27
1.95
2.8
2.9
164.36
189.08
ng/l
0.34
122
1031
27
157
1.73
1.92
2.9
2.6
1.98
1.72
g/24h
0.12
13
81
1793
17532
1.21
1.92
13.1
9.8
27.92
27.14
u/l
0.72
1753
16992
85
635
1.35
1.92
2.1
2.2
20.49
21.15
s
0.87
70
557
23
128
1.81
1.89
1.4
1.4
—
—
—
0
0
311
2704
1.18
1.88
1.7
1.6
—
—
—
0
0
12
52
2.31
1.87
2.3
2.1
95.52
60.56
ug/l
0.47
12
52
15
73
2.06
1.80
32.1
27.6
96.04
126.87
ug/l
1.76
15
57
52
361
1.45
1.80
1.7
1.7
11948.80
11987.86
e6/l
0.00
45
270
1529
14787
1.14
1.78
5.6
5.3
39.48
39.33
mmol/mol
0.24
1430
13792
23
131
1.76
1.77
1.2
1.3
60477.00
162433.65
e6/l
0.74
16
74
314
2746
1.17
1.77
3.4
3.0
2.44
2.44
mmol/l
0.08
279
2420
69
506
1.38
1.77
7.3
9.1
—
—
—
0
0
1552
15028
1.14
1.76
5.2
4.6
1.84
2.03
mu/l
0.98
1442
13895
176
1462
1.22
1.75
4.0
4.2
10.85
19.05
ug/l
0.42
132
1190
42
281
1.50
1.74
3.0
3.8
123.33
1358.74
u/ml
0.79
37
270
160
1318
1.23
1.73
1.4
1.5
—
—
—
0
0
424
3799
1.15
1.73
1.3
1.3
2.22
1.63
u/ml
0.26
111
1038
26
155
1.69
1.72
3.0
2.7
—
—
—
0
0
73
543
1.36
1.72
1.8
1.4
11.44
9.02
u/l
0.65
63
441
13
61
2.14
1.71
2.3
1.5
—
—
—
0
0
123
985
1.26
1.71
2.8
2.4
—
—
—
0
0
212
1799
1.20
1.70
1.6
1.3
—
—
—
0
0
20
111
1.81
1.68
2.6
2.9
42.80
43.08
%
0.02
13
55
22
126
1.75
1.68
1.1
1.1
—
—
—
0
0
159
1315
1.23
1.66
2.4
2.3
12.56
13.03
nmol/l
0.31
140
1192
45
309
1.47
1.66
1.1
1.1
—
—
—
0
0
45
309
1.47
1.66
1.1
1.1
—
—
—
0
0
6
19
3.16
1.66
1.5
1.2
—
—
—
0
0
39
260
1.51
1.66
1.2
1.2
—
—
—
0
0
60
437
1.38
1.62
2.8
3.4
30.57
39.49
mg/l
0.57
48
342
20
113
1.78
1.60
1.4
1.1
1.09
1.04
ratio
—
10
46
71
534
1.34
1.58
4.2
3.5
467.67
2707.37
u/ml
0.62
61
455
142
1168
1.23
1.58
1.2
1.2
92.77
146.71
iu/ml
1.08
51
453
30
192
1.57
1.54
2.3
3.0
—
—
—
0
0
219
1885
1.18
1.52
1.4
1.4
—
—
—
0
0
45
316
1.43
1.51
3.2
2.8
1.48
1.58
mmol/l
0.34
45
305
16
86
1.87
1.50
4.1
4.0
—
—
—
0
0
485
4424
1.13
1.50
4.1
3.2
—
—
—
0
0
59
437
1.36
1.46
2.8
3.4
43.19
65.16
mg/l
0.73
47
341
57
420
1.37
1.46
2.0
2.4
37.07
38.12
g/l
0.56
49
379
22
132
1.67
1.46
2.4
2.9
97.78
13.04
mg/l
0.95
17
97
16
87
1.85
1.45
1.3
1.3
121.25
143.84
nmol/l
1.35
16
87
86
674
1.29
1.45
1.9
1.6
296.65
297.38
mu/l
0.01
79
613
93
738
1.27
1.43
4.2
3.4
—
—
—
0
0
75
579
1.31
1.42
1.3
1.3
163.06
222.96
miu/ml
1.04
36
275
7
29
2.42
1.39
1.4
1.4
—
—
—
0
0
521
4795
1.12
1.38
3.4
3.2
7.87
7.82
mmol/l
0.08
441
4105
64
486
1.33
1.37
1.2
1.2
—
—
—
0
0
61
461
1.33
1.35
1.1
1.3
90.00
93.00
titre
—
5
40
28
183
1.54
1.34
1.5
1.8
53.05
58.16
%
0.24
21
125
20
120
1.67
1.34
1.3
1.3
—
—
—
0
0
40
282
1.43
1.34
1.3
1.2
8.65
5.04
u/ml
0.53
17
114
156
1320
1.20
1.34
1.2
1.2
—
—
—
0
0
43
308
1.40
1.32
3.0
2.4
16.52
16.28
%
0.10
23
156
45
325
1.39
1.32
2.7
3.6
—
—
—
0
0
5
18
2.78
1.28
1.4
1.3
—
—
—
0
0
38
268
1.43
1.28
1.2
1.3
—
—
—
0
0
38
269
1.42
1.26
4.4
2.7
—
—
—
0
0
47
346
1.37
1.25
1.4
1.3
243.12
251.78
u/ml
0.08
32
214
5
19
2.63
1.21
1.4
1.2
—
—
—
0
0
23
148
1.56
1.20
1.2
1.3
3322.89
1968.96
e6/l
0.34
18
104
41
298
1.38
1.18
1.8
1.6
—
—
—
0
0
33
231
1.44
1.17
2.2
1.8
—
—
—
0
0
14
79
1.78
1.17
2.2
2.2
1.84
1.97
ug/l
—
9
69
164
1894
0.85
1.17
1.4
1.3
—
—
—
0
0
5
20
2.50
1.15
1.0
1.4
—
—
—
0
0
33
234
1.42
1.11
1.6
1.5
—
—
—
0
0
19
120
1.59
1.08
1.8
1.9
10.97
11.12
%
0.06
19
120
29
202
1.44
1.07
2.6
2.2
8.53
5.92
umol/l
0.54
20
141
26
178
1.47
1.05
2.4
2.3
—
—
—
0
0
224
1996
1.14
1.04
1.3
1.3
—
—
—
0
0
36
263
1.38
1.03
1.4
1.4
20.89
24.57
u/l
0.40
30
212
142
1224
1.17
1.03
5.5
3.7
1.21
1.23
mmol/l
2.63
131
1059
7
34
2.06
1.03
1.0
1.1
—
—
—
0
0
7
34
2.06
1.03
1.0
1.1
—
—
—
0
0
7
34
2.06
1.03
1.0
1.1
—
—
—
0
0
1754
17265
1.13
1.00
17.3
12.2
—
—
—
0
0
14
84
1.67
0.97
1.9
1.8
—
—
—
0
0
0
30
0.00
0.97
0.0
2.1
—
—
—
0
0
39
296
1.32
0.91
3.4
2.9
7.93
7.36
mmol/l
0.45
39
288
11
63
1.75
0.90
1.2
1.2
—
—
—
0
0
32
236
1.36
0.89
1.2
1.5
—
—
—
0
0
9
154
0.58
0.88
1.0
1.1
—
—
—
0
0
192
1715
1.13
0.88
1.5
1.4
—
—
—
0
0
10
56
1.79
0.87
1.1
1.4
—
—
—
0
0
6
30
2.00
0.87
33.7
6.9
—
—
—
0
0
20
136
1.47
0.86
1.5
1.6
27.93
32.35
%
0.21
15
90
81
678
1.20
0.85
2.2
2.2
1286.66
4186.73
u/l
1.89
29
262
36
273
1.32
0.85
1.4
1.7
—
—
—
0
0
101
1175
0.85
0.84
1.3
1.4
—
—
—
0
0
10
57
1.76
0.83
1.0
1.1
—
—
—
0
0
19
129
1.48
0.83
1.2
1.3
—
—
—
0
0
17
113
1.51
0.82
2.1
2.0
—
—
—
0
0
15
97
1.55
0.81
1.1
1.2
—
—
—
0
0
13
81
1.61
0.81
1.0
1.1
—
—
—
0
0
11
66
1.67
0.78
5.6
2.5
0.87
1.41
ug/l
0.74
11
60
204
1847
1.12
0.77
1.6
1.7
—
—
—
0
0
37
287
1.29
0.77
1.1
1.1
—
—
—
0
0
20
140
1.43
0.76
1.6
1.5
—
—
—
0
0
460
4332
1.08
0.75
3.6
3.3
772.39
357.88
mg/l
0.73
300
2796
73
615
1.19
0.74
1.5
2.1
—
—
—
0
0
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
7
38
1.84
0.73
1.9
2.0
20.64
17.24
umol/l
—
7
38
9
56
1.61
0.72
1.0
1.0
—
—
—
0
0
125
1104
1.14
0.71
1.4
1.4
—
—
—
0
0
17
117
1.46
0.71
1.1
1.1
—
—
—
0
0
36
283
1.28
0.69
1.1
1.1
118.38
121.69
iu/ml
—
8
70
5
27
1.85
0.68
1.6
1.6
—
—
—
0
0
10
61
1.64
0.68
3.7
2.8
—
—
—
0
0
36
284
1.27
0.68
1.1
1.1
—
—
—
0
0
10
156
0.64
0.67
1.2
1.1
—
—
—
0
0
1148
11182
1.06
0.67
3.7
3.5
—
—
—
0
0
98
856
1.15
0.67
1.6
1.4
26.58
26.73
iu/l
0.01
87
728
7
43
1.63
0.66
1.6
1.8
—
—
—
0
0
54
451
1.20
0.63
1.1
1.1
—
—
—
0
0
74
636
1.17
0.63
1.7
1.7
—
—
—
0
0
88
767
1.15
0.63
2.6
2.3
—
—
—
0
0
8
50
1.60
0.61
7.0
12.5
—
—
—
0
0
478
4548
1.07
0.60
4.2
3.9
17.24
8.90
mg/mmol
1.49
311
2902
43
354
1.22
0.59
2.0
2.2
0.86
0.86
nmol/l
0.01
36
302
14
97
1.45
0.59
2.6
2.9
43521.43
41080.46
ug/l
0.43
14
97
6
35
1.72
0.57
2.2
1.9
—
—
—
0
0
8
55
1.46
0.56
1.0
1.6
293.63
97.28
nmol/24h
—
8
55
44
368
1.20
0.53
5.0
4.4
—
—
—
0
0
14
100
1.40
0.51
1.1
1.5
5.17
6.63
u/l
—
9
80
15
109
1.38
0.51
1.0
1.1
8.62
10.56
iu/ml
—
5
27
43
362
1.19
0.49
1.3
1.2
—
—
—
0
0
60
522
1.15
0.47
2.4
2.6
—
—
—
0
0
19
147
1.29
0.45
2.6
2.0
—
—
—
0
0
18
139
1.30
0.43
1.3
1.4
1.16
1.49
nmol/l
1.00
18
124
33
275
1.20
0.43
1.5
1.4
0.33
0.33
nmol/l
0.03
24
221
29
350
0.83
0.43
1.9
1.6
—
—
—
0
0
11
78
1.41
0.43
1.1
1.3
—
—
—
0
0
11
78
1.41
0.43
38.6
34.9
6.53
7.52
ug/l
1.37
11
69
5
32
1.56
0.42
1.4
1.7
—
—
—
0
0
5
32
1.56
0.42
3.0
3.8
118.40
77.28
ng/l
—
5
19
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
32
268
1.20
0.41
1.2
1.0
2.22
2.35
u/ml
—
10
126
8
60
1.33
0.40
6.4
4.8
—
—
—
0
0
9
67
1.34
0.38
1.9
3.3
11.15
8.21
mg/l
—
9
60
5
78
0.64
0.35
1.0
1.1
110.20
201.69
iu/ml
—
5
78
33
282
1.17
0.35
6.8
2.8
—
—
—
0
0
29
245
1.19
0.35
1.5
1.5
—
—
—
0
0
9
125
0.72
0.35
1.2
1.4
—
—
—
0
0
11
82
1.34
0.34
1.6
1.4
—
—
—
0
0
6
45
1.33
0.33
1.2
1.2
331.83
285.31
pmol/l
—
6
29
14
109
1.29
0.33
1.0
1.0
—
—
—
0
0
1450
14340
1.04
0.32
20.9
15.5
14.97
14.68
%
1.09
1437
14079
6
47
1.28
0.32
1.0
1.0
—
—
—
0
0
7
55
1.27
0.30
1.1
1.1
—
—
—
0
0
39
344
1.14
0.29
2.0
2.8
—
—
—
0
0
46
412
1.12
0.28
1.6
2.0
2.77
4.87
iu/l
2.22
16
146
10
76
1.32
0.28
1.1
1.2
—
—
—
0
0
78
721
1.08
0.26
1.5
2.2
—
—
—
0
0
19
159
1.20
0.26
1.2
1.2
—
—
—
0
0
73
676
1.08
0.24
1.1
1.1
—
0.91
—
0
10
9
77
1.17
0.24
1.8
1.4
138.82
170.50
mmol/24h
—
9
77
6
83
0.72
0.24
1.3
1.4
—
—
—
0
0
1424
14358
0.97
0.23
22.5
16.4
332.85
332.96
g/l
0.17
1415
14252
23
199
1.16
0.23
1.2
1.3
—
—
nmol/l
—
0
0
12
97
1.24
0.22
1.2
1.2
—
—
—
0
0
5
41
1.22
0.22
1.0
1.0
—
—
—
0
0
46
420
1.10
0.21
2.0
1.9
196.63
201.83
pmol/l
0.13
46
396
41
372
1.10
0.21
2.3
2.3
45.93
115.36
ug/min
1.93
21
234
5
42
1.19
0.21
1.4
1.3
91.98
65.84
mu/l
—
5
33
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
35.71
—
0
10
0
10
0.00
0.21
0.0
1.1
—
0.17
—
0
5
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
11.83
—
0
11
1584
15734
1.03
0.21
4.5
4.2
5.92
5.88
mmol/l
0.46
1461
14452
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
0.21
—
0
5
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
5
43
1.16
0.21
1.2
1.1
37.46
30.97
%
—
5
37
0
13
0.00
0.21
0.0
1.0
—
0.25
—
0
6
19
164
1.16
0.20
1.2
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
29.00
—
0
5
9
113
0.80
0.20
1.2
1.3
1.45
1.56
g/l
—
9
113
456
4657
0.97
0.19
1.4
1.5
—
—
—
0
0
7
58
1.21
0.18
1.1
1.7
—
—
—
0
0
29
321
0.90
0.18
1.1
1.1
16.18
5.31
u/ml
1.05
18
169
81
765
1.06
0.18
1.5
2.1
—
—
—
0
0
7
61
1.15
0.17
1.0
1.3
—
—
—
0
0
7
61
1.15
0.17
1.0
1.0
—
—
—
0
0
16
138
1.16
0.17
1.2
1.1
—
—
—
0
0
8
69
1.16
0.16
6.1
2.5
—
—
—
0
0
22
196
1.12
0.16
3.1
2.3
—
—
—
0
0
39
360
1.08
0.16
1.2
1.3
—
—
—
0
0
1853
18471
1.04
0.16
26.9
19.1
40.14
40.49
%
1.62
1768
17404
33
359
0.92
0.15
1.2
1.1
1.08
2.82
u/ml
1.30
19
186
20
224
0.89
0.15
1.1
1.0
0.05
0.38
u/ml
—
5
70
56
527
1.06
0.14
2.4
2.9
—
—
—
0
0
1563
15550
1.02
0.14
3.9
3.8
1.39
1.32
mmol/l
2.08
1467
14393
24
264
0.91
0.14
1.0
1.0
5.28
2.91
u/ml
0.36
12
126
27
247
1.09
0.13
3.1
3.1
0.74
0.85
nmol/l
0.58
19
197
24
261
0.92
0.11
1.2
1.2
—
—
—
0
0
17
153
1.11
0.11
1.2
1.3
168.65
218.31
pmol/l
0.34
17
153
272
2769
0.98
0.11
2.9
2.8
0.64
0.71
ug/l
1.21
174
1687
109
1056
1.03
0.10
1.2
1.2
—
—
—
0
0
1628
16222
1.02
0.10
4.3
4.2
4.73
4.71
mmol/l
0.36
1532
15193
20
183
1.09
0.10
2.3
2.3
33.95
32.14
pg
1.51
20
183
12
106
1.13
0.09
1.1
1.0
—
—
—
0
0
1852
18480
1.03
0.09
26.9
19.0
254.41
253.00
e9/l
0.40
1825
18064
81
783
1.04
0.09
1.5
2.1
—
—
—
0
0
24
223
1.08
0.09
1.3
1.3
0.54
0.62
nmol/l
0.57
24
212
6
55
1.09
0.09
2.2
2.5
—
—
—
0
0
6
55
1.09
0.09
2.5
2.5
—
—
—
0
0
35
331
1.06
0.08
5.1
3.6
22.68
23.80
mg/l
0.07
20
218
1853
18492
1.02
0.08
26.7
19.0
90.60
90.71
fl
0.50
1836
18260
430
4252
1.01
0.08
1.6
1.7
1.54
1.40
mmol/l
0.83
371
3614
5
61
0.82
0.08
1.2
1.1
—
—
—
0
0
7
65
1.08
0.08
1.0
1.6
—
—
—
0
0
1853
18494
1.02
0.08
26.7
18.9
30.21
30.27
pg
0.74
1836
18260
7
67
1.04
0.08
1.9
1.7
—
—
—
0
0
80
776
1.03
0.08
1.5
2.1
—
—
—
0
0
81
786
1.03
0.08
1.5
2.1
—
—
—
0
0
1853
18495
1.02
0.07
26.8
19.0
4.50
4.54
e12/l
2.46
1820
18032
12
133
0.90
0.07
1.2
1.5
0.91
0.98
g/l
0.72
12
133
105
1025
1.03
0.07
1.6
1.6
—
—
—
0
0
29
306
0.95
0.07
1.1
1.1
0.79
2.02
u/ml
1.23
14
157
136
1387
0.98
0.07
5.4
3.8
—
—
—
0
0
1853
18497
1.02
0.07
26.9
19.0
6.96
6.71
e9/l
3.03
1824
18035
9
87
1.03
0.07
1.6
2.6
—
—
—
0
0
27
285
0.95
0.06
1.2
1.2
—
—
—
0
0
37
354
1.05
0.06
1.4
1.4
—
—
—
0
0
479
4751
1.01
0.06
4.9
4.4
2.56
2.29
ug/l
0.19
437
4280
17
158
1.08
0.06
3.1
4.4
14.94
84.26
u/ml
—
7
46
1853
18502
1.02
0.05
27.0
19.1
135.15
136.61
g/l
4.29
1839
18266
37
356
1.04
0.05
1.4
1.4
—
—
—
0
0
11
100
1.10
0.05
1.0
1.0
—
—
—
0
0
38
366
1.04
0.05
1.5
1.5
—
—
—
0
0
30
311
0.96
0.03
1.1
1.1
1.89
1.64
u/ml
0.08
17
136
76
773
0.98
0.03
1.0
1.1
—
—
—
0
0
23
237
0.97
0.01
1.0
1.1
4.19
5.61
u/ml
—
9
95
1646
16464
1.00
0.01
4.7
4.6
2.82
2.81
mmol/l
0.07
1535
15325
13
124
1.05
0.00
1.2
1.3
84.00
76.60
umol/l
0.41
13
124
37
370
1.00
0.00
1.1
1.3
—
—
—
0
0
11
108
1.02
0.00
1.0
1.0
—
—
—
0
0
12
122
0.98
0.00
8.8
15.1
563.17
817.53
nmol/l
1.14
12
117
21
206
1.02
0.00
1.3
1.3
—
—
—
0
0
1614
16131
1.00
0.00
4.3
4.2
1.45
1.45
mmol/l
0.20
1509
15020
10
95
1.05
0.00
5.1
6.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
2.60
—
0
6
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1184.40
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
2.7
2.8
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
-0.00
2.0
1.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint MENINGITIS and mortality.

Females

Parameter HR [95% CI] p-value
MENINGITIS 2.303 [1.99, 2.66] < 0.001
Birth year 0.995 [0.99, 1.0] 0.211

During the follow-up period (1.1.1998 — 31.12.2019), 686 out of 3805 females with MENINGITIS died.

Males

Parameter HR [95% CI] p-value
MENINGITIS 2.327 [2.0, 2.71] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 823 out of 3963 males with MENINGITIS died.

Mortality risk

Mortality risk for people of age

years, who have MENINGITIS.

N-year risk Females Males
1 0.233% 0.438%
5 1.237% 2.553%
10 3.441% 6.493%
15 6.682% 11.706%
20 10.829% 19.098%

Relationships between endpoints

Index endpoint: MENINGITIS – Meningitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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