No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
1936 |
6. Filter based on genotype QC (FinnGen only) |
1936 |
Control definitions (FinnGen only)
- Control exclude
- AB1_VIRAL_CNS
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Meningitis
based on the number of shared cases.
Similar with more cases:
- Inflammatory diseases of the central nervous system
- Neurological diseases
- Neurological diseases, wide definition
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 18175 | 8439 | 9598 |
| Only index persons | 14933 | 7258 | 7675 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.25 | 0.24 | 0.27 |
| Only index persons | 0.28 | 0.27 | 0.29 |
| Median age at first event (years) | |||
| Whole population | 29.98 | 32.14 | 27.70 |
| Only index persons | 26.99 | 29.97 | 24.16 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1936 | 1088 | 848 |
| Unadjusted period prevalence (%) | 0.37 | 0.37 | 0.37 |
| Median age at first event (years) | 33.45 | 32.38 | 34.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1744
- Matched controls
- 17441
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
32099
ICD-8 Finland
Meningitis, With no organism specified as cause
+∞
323.0
335
*
G03.9
ICD-10 Finland
Meningitis, unspecified
+∞
323.0
362
*
G00.9
ICD-10 Finland
Bacterial meningitis, unspecified
+∞
275.5
257
*
32088
ICD-8 Finland
Meningitis, Alia definita
+∞
191.2
180
*
A87.9
ICD-10 Finland
Viral meningitis, unspecified
2042.1
183.6
175
*
TAB00
NOMESCO Finland
Lumbar puncture
10.1
135.7
286
331
32000
ICD-8 Finland
Meningitis, H. influenzae
+∞
106.3
101
*
G01*A69.2
ICD-10 Finland
Meningitis (in) Lyme disease
958.1
93.8
91
*
3229X
ICD-9 Finland
Meningitis of unspecified cause, Meningitis, unspecified
+∞
83.0
79
*
G00.1
ICD-10 Finland
Pneumococcal meningitis
+∞
81.9
78
*
G02.0*B00.3
ICD-10 Finland
Herpesviral meningitis
+∞
78.7
75
*
AA1AD
NOMESCO Finland
CT of head and brain
2.8
62.1
501
2205
R51.80
ICD-10 Finland
Headache
3.1
59.6
392
1507
A86
ICD-10 Finland
Unspecified viral encephalitis
+∞
54.5
52
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.9
52.0
234
666
G01*A39.0
ICD-10 Finland
Meningococcal meningitis
+∞
40.8
39
*
G03.0
ICD-10 Finland
Nonpyogenic meningitis
+∞
39.7
38
*
G03.8
ICD-10 Finland
Meningitis due to other specified causes
+∞
36.6
35
*
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
48.5
31.6
38
8
AAF00
NOMESCO Finland
Ventriculostomy
15.7
30.0
49
32
G03.1
ICD-10 Finland
Chronic meningitis
+∞
29.2
28
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
29.2
279
1285
G00.2
ICD-10 Finland
Streptococcal meningitis
+∞
28.2
27
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
48.0
27.5
33
7
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
10.5
26.6
52
51
G02.0*B02.1
ICD-10 Finland
Zoster meningitis
+∞
26.1
25
*
R50.9
ICD-10 Finland
Fever, unspecified
2.3
26.0
273
1314
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.7
25.6
90
201
G00.8
ICD-10 Finland
Other bacterial meningitis
+∞
25.1
24
*
0499X
ICD-9 Finland
Other non-arthropod-borne viral diseases of central nervous system, Unspecified non-arthropod-borne viral diseases of central nervous system
+∞
25.1
24
*
G02.0
ICD-10 Finland
Meningitis in viral diseases classified elsewhere
+∞
25.1
24
*
G00.3
ICD-10 Finland
Staphylococcal meningitis
+∞
25.1
24
*
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
14.4
24.4
41
29
N71
ICPC
Meningitis/encephalitis
+∞
24.0
23
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
23.8
244
1156
3209X
ICD-9 Finland
Bacterial meningitis, Meningitis due to unspecified bacterium
+∞
23.0
22
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
21.9
683
4839
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
18.7
21.7
33
18
G02.0*B01.0
ICD-10 Finland
Varicella meningitis
+∞
20.9
20
*
A69.2
ICD-10 Finland
Lyme disease
3.2
20.8
112
364
5AB01
NOMESCO Finland
NA
77.8
20.7
23
*
G01*A32.1
ICD-10 Finland
Listerial meningitis
+∞
19.8
19
*
G01
ICD-10 Finland
Meningitis in bacterial diseases classified elsewhere
+∞
19.8
19
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.9
19.3
120
429
G91.0
ICD-10 Finland
Communicating hydrocephalus
13.4
19.2
33
25
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
19.2
168
734
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
18.8
344
2047
G02.0*A87.0
ICD-10 Finland
Enteroviral meningitis
+∞
18.8
18
*
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
70.7
18.7
21
*
R51
ICD-10 Finland
Headache
2.8
18.1
120
448
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
8.5
18.0
39
47
J05AB11
ATC
valaciclovir; oral
2.0
17.9
234
1228
A87.8
ICD-10 Finland
Other viral meningitis
+∞
17.7
17
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
17.5
152
661
04599
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Aseptic meningitis, unspecified
+∞
16.7
16
*
32010
ICD-8 Finland
Meningitis, Pneumococcus
+∞
16.7
16
*
G03.2
ICD-10 Finland
Benign recurrent meningitis [Mollaret]
+∞
16.7
16
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
16.5
261
1473
N03AX14
ATC
levetiracetam; systemic
3.9
16.0
66
174
N03AX16
ATC
pregabalin; oral
1.7
16.0
384
2479
G51.0
ICD-10 Finland
Bell palsy
3.9
15.9
65
170
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
6.7
15.9
40
61
N02AX02
ATC
tramadol; systemic, rectal
1.5
14.7
654
4925
N03AX12
ATC
gabapentin; oral
1.9
14.7
251
1450
3200A
ICD-9 Finland
Bacterial meningitis, Haemophilus meningitis
+∞
14.6
14
*
A39.0
ICD-10 Finland
Meningococcal meningitis
+∞
14.6
14
*
H02AB06
ATC
prednisolone; systemic
1.5
14.5
740
5740
J05AB01
ATC
aciclovir; systemic
1.7
14.4
335
2134
R42
ICD-10 Finland
Dizziness and giddiness
1.7
14.1
324
2057
SPAT1255
SPAT
Intravenous administration of medicine
2.5
13.8
113
477
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
12.1
13.6
24
20
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
6.6
13.6
34
52
G05.1*B00.4
ICD-10 Finland
Herpesviral meningoencephalitis
141.1
13.5
14
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.0
13.3
76
259
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
22.7
12.9
18
8
XA800
NOMESCO Finland
Neuropsychological investigation
2.7
12.8
88
337
G00.0
ICD-10 Finland
Haemophilus meningitis
130.9
12.4
13
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.6
12.4
89
350
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
4.5
12.1
42
95
N02BE01
ATC
paracetamol; systemic, rectal
1.5
12.0
1382
12449
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
11.9
326
2165
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.8
11.9
49
131
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
11.8
553
4158
WX882
NOMESCO Finland
High dependency care
3.3
11.8
58
179
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
4.8
11.7
38
81
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.7
11.6
78
297
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
6.2
11.5
30
49
3201A
ICD-9 Finland
Bacterial meningitis, Pneumococcal meningitis
+∞
11.5
11
*
B00.3
ICD-10 Finland
Herpesviral meningitis
+∞
11.5
11
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.9
11.4
46
121
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
11.3
812
6627
H02AB07
ATC
prednisone; oral
1.8
11.3
218
1307
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
15.1
11.3
18
12
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
11.3
273
1749
N03AF02
ATC
oxcarbazepine; oral
2.9
11.2
66
232
A41.9
ICD-10 Finland
Sepsis, unspecified
3.1
11.1
61
204
G44.2
ICD-10 Finland
Tension-type headache
1.7
10.9
219
1331
N03AB02
ATC
phenytoin; systemic
5.6
10.7
30
54
J01DB01
ATC
cefalexin; oral
1.5
10.7
1345
12128
G91.1
ICD-10 Finland
Obstructive hydrocephalus
8.0
10.6
23
29
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.2
10.6
39
95
N05CF01
ATC
zopiclone; oral
1.5
10.5
465
3444
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
10.4
406
2920
A87.0
ICD-10 Finland
Enteroviral meningitis
+∞
10.4
10
*
B00.4
ICD-10 Finland
Herpesviral encephalitis
+∞
10.4
10
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
10.4
244
1550
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
10.2
148
804
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
10.2
336
2330
N06AA09
ATC
amitriptyline; systemic
1.9
9.9
154
860
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
9.9
155
867
A02BC02
ATC
pantoprazole; systemic
1.4
9.9
982
8413
J01AA02
ATC
doxycycline; systemic
1.4
9.7
1229
10963
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
5.6
9.7
27
49
TKC20
NOMESCO Finland
Catheterisation of bladder
2.2
9.6
100
478
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
8.4
9.6
20
24
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
15.1
9.5
15
10
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
9.4
548
4262
ABE50
NOMESCO Finland
Occipitocervical decompression
100.6
9.4
10
*
G09
ICD-10 Finland
Sequelae of inflammatory diseases of central nervous system
100.6
9.4
10
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
9.4
564
4414
G63.0*A69.2
ICD-10 Finland
Polyneuropathy (in) Lyme disease
21.8
9.3
13
6
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
9.3
95
450
H53.2
ICD-10 Finland
Diplopia
3.0
9.3
53
182
WX730
NOMESCO Finland
Conventional respirator
4.7
9.2
30
65
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
9.2
288
1970
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.0
9.1
35
89
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
6.7
9.1
22
33
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.6
9.1
65
256
AAK40
NOMESCO Finland
Closure of cerebrospinal fluid fistula
36.9
9.0
11
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
9.0
78
344
N73
ICPC
Neurological infection other
24.1
8.9
12
5
N01
ICPC
Headache
1.8
8.9
169
1007
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.2
8.8
84
385
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.9
8.8
120
641
J01FF01
ATC
clindamycin; systemic
1.4
8.8
408
3034
B34.9
ICD-10 Finland
Viral infection, unspecified
2.9
8.8
51
178
AA1AA
NOMESCO Finland
Head X-ray examination
6.4
8.8
22
35
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
8.7
395
2922
J01DA01
ATC
[U] cefalexin; systemic
1.4
8.7
981
8498
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
7.7
8.6
19
25
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
8.6
337
2421
AAF15
NOMESCO Finland
Ventriculoatrial shunt
11.6
8.6
15
13
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
3.9
8.4
33
86
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
8.4
119
644
J01EA01
ATC
trimethoprim; systemic
1.5
8.4
349
2534
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.2
8.4
42
134
B02.1
ICD-10 Finland
Zoster meningitis
+∞
8.3
8
*
N03AG01
ATC
valproic acid; systemic, rectal
2.0
8.3
102
524
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
8.2
696
5744
N03AF01
ATC
carbamazepine; oral, rectal
2.1
8.1
85
409
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.1
8.1
93
464
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
8.1
260
1786
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.6
7.9
191
1220
R03AC02
ATC
salbutamol; inhalant
1.3
7.9
806
6828
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.8
425
3244
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
7.8
159
969
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
4.5
7.8
26
59
P01BA02
ATC
hydroxychloroquine; oral
1.8
7.7
120
671
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
7.6
108
583
ZXC95
NOMESCO Finland
Use of surgical navigator
4.0
7.6
28
70
A32.7
ICD-10 Finland
Listerial sepsis
25.1
7.6
10
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.8
7.6
48
177
ZX120
NOMESCO Finland
Intravenous
1.8
7.5
137
809
J01CA04
ATC
amoxicillin; systemic
1.4
7.5
1301
11902
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
7.5
227
1537
L04AX01
ATC
azathioprine; systemic
2.2
7.5
75
354
G05.1
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
80.4
7.4
8
*
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
13.4
7.4
12
9
SPAT1153
SPAT
Removal of sutures
1.4
7.3
434
3362
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
3.5
7.3
32
93
AAE05
NOMESCO Finland
Nasoendoscopic closure of cerebrospinal fluid fistula
+∞
7.3
7
*
B94.80
ICD-10 Finland
Late effects of bacterial meningitis
+∞
7.3
7
*
R40.2
ICD-10 Finland
Coma, unspecified
6.3
7.2
18
29
101
Kela drug reimbursment
Anterior pituitary hypofunction
5.8
7.2
19
33
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
7.2
105
576
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.6
7.2
50
197
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.2
7.1
72
341
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.8
7.1
42
151
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.8
7.1
108
603
N05BA04
ATC
oxazepam; oral
1.4
7.0
352
2641
R53
ICD-10 Finland
Malaise and fatigue
1.5
7.0
279
2006
G43.9
ICD-10 Finland
Migraine, unspecified
1.9
7.0
91
479
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
6.9
193
1281
M01AE02
ATC
naproxen; oral, rectal
1.3
6.9
865
7493
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.9
550
4464
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
5.5
6.9
19
35
N03AX18
ATC
lacosamide; systemic
5.9
6.9
18
31
ZZC00
NOMESCO Finland
Graft of fascia
13.8
6.9
11
8
AAK00
NOMESCO Finland
Cranioplasty
13.8
6.9
11
8
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
4.1
6.9
25
62
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.1
6.9
25
62
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
6.9
104
576
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
6.9
69
328
N30.0
ICD-10 Finland
Acute cystitis
1.6
6.9
192
1273
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
2.3
6.8
61
275
J01FA10
ATC
azithromycin; systemic
1.3
6.8
915
8002
6BA02
NOMESCO Finland
NA
9.3
6.8
13
14
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
6.8
140
859
H47.1
ICD-10 Finland
Papilloedema, unspecified
5.7
6.8
18
32
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.8
6.8
40
144
Q07.0
ICD-10 Finland
Arnold-Chiari syndrome
16.8
6.7
10
6
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
4.3
6.7
23
54
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
4.1
6.7
24
59
79199
ICD-8 Finland
Headache
3.7
6.7
27
74
9560/0-C72.4
ICD-O-3
Schwannoma, NOS, of acoustic nerve
22.6
6.7
9
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.9
6.6
91
491
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
4.2
6.6
23
55
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
7.8
6.6
14
18
N03AE01
ATC
clonazepam; systemic
1.9
6.6
86
452
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
6.6
404
3140
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.2
6.6
62
287
WX704
NOMESCO Finland
Intubation
1.8
6.5
105
596
TDM10
NOMESCO Finland
Puncture of maxillary antrum
2.2
6.5
61
282
B01AA03
ATC
warfarin; systemic
1.5
6.4
223
1554
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.2
6.4
31
98
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
6.4
166
1080
N02AA05
ATC
oxycodone; systemic
1.6
6.3
176
1164
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.0
6.3
80
417
J01MA14
ATC
moxifloxacin; systemic
1.7
6.3
122
733
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
6.2
312
2338
G06.0
ICD-10 Finland
Intracranial abscess and granuloma
26.8
6.2
8
*
N02CA01
ATC
dihydroergotamine; nasal, systemic
7.0
6.2
14
20
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
6.2
286
2110
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.0
6.2
33
112
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
2.9
6.2
36
128
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.0
6.2
79
414
UDC00
NOMESCO Finland
Ear microscopy
1.8
6.1
102
587
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.2
6.1
58
269
WX872
NOMESCO Finland
Intensive care
2.1
6.1
66
326
N06AX16
ATC
venlafaxine; oral
1.5
6.1
205
1421
N28
ICPC
Limited function/disability (N)
3.7
6.1
24
65
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
6.0
138
872
N03AX11
ATC
topiramate; oral
2.5
6.0
43
172
L28
ICPC
Limited function/disability (L)
1.5
6.0
186
1264
R60.0
ICD-10 Finland
Localized oedema
1.6
6.0
136
856
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
5.2
6.0
17
33
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
362
395
11.04
309.86
2.0
1.3
1044.9
492.3
mg/l
13.64
350
372
270
137
22.73
307.65
2.1
1.7
—
—
—
0
0
341
347
11.71
306.48
1.8
1.2
3.3
3.7
mmol/l
6.33
320
325
174
74
25.73
245.82
1.3
1.1
—
—
—
0
0
166
64
28.27
242.99
1.9
2.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
170
80
23.19
230.64
1.3
1.1
—
—
—
0
0
292
353
9.56
229.33
1.9
1.4
323.7
24.4
e6/l
3.66
239
272
292
353
9.56
229.33
2.0
1.5
827.0
697.7
e6/l
0.11
243
286
158
114
15.00
173.99
2.1
1.2
3.5
1.9
mmol/l
6.50
153
108
160
176
9.82
133.57
1.3
1.0
72.5
—
au/ml
—
9
0
106
59
18.94
132.89
1.2
1.1
539.1
37.7
ng/l
—
59
9
99
49
21.23
130.75
1.4
1.1
—
—
—
0
0
149
159
10.07
127.13
1.1
1.0
—
—
—
0
0
98
55
18.71
122.30
1.2
1.2
—
—
—
0
0
83
41
21.10
109.55
1.3
1.1
—
—
—
0
0
82
42
20.34
106.53
1.3
1.1
—
—
—
0
0
75
37
21.04
98.96
1.3
1.1
—
—
—
0
0
70
32
22.65
95.28
1.2
1.1
—
—
—
0
0
69
38
18.79
86.62
1.3
1.1
—
—
—
0
0
69
41
17.41
83.53
1.2
1.0
—
—
—
0
0
72
48
15.54
82.20
1.1
1.0
—
—
—
0
0
54
22
25.21
76.66
2.1
1.2
54.4
38.0
%
—
47
6
77
76
10.51
69.09
2.0
1.1
51.4
61.7
%
—
41
7
46
18
26.15
66.16
1.3
1.2
—
—
—
0
0
46
20
23.53
63.62
1.3
1.2
—
—
—
0
0
82
101
8.43
62.23
1.3
1.1
—
—
—
0
0
40
16
25.50
56.99
1.1
1.0
—
—
—
0
0
47
28
17.17
56.65
1.2
1.1
—
—
—
0
0
290
1105
2.91
54.61
2.9
2.4
38.1
23.6
au/ml
0.81
12
73
271
1006
2.97
53.45
1.6
1.3
53.2
41.9
au/ml
—
10
47
52
47
11.34
49.42
1.7
1.2
25.6
22.6
%
—
35
5
89
158
5.85
48.20
1.6
1.7
—
—
—
0
0
96
188
5.32
46.77
5.4
6.4
10.2
11.4
mg/l
1.52
87
169
37
21
17.94
45.54
1.2
1.0
—
—
—
0
0
37
22
17.12
44.53
1.2
1.0
—
—
—
0
0
28
12
23.65
38.69
1.4
1.2
—
—
—
0
0
28
15
18.92
35.26
1.2
1.1
—
—
—
0
0
65
139
4.80
28.60
1.3
1.1
80.5
41.3
mg/l
3.43
57
109
252
1205
2.25
28.57
3.8
2.7
10.0
10.5
g/l
1.31
241
1100
86
231
3.85
28.17
1.2
1.1
—
—
—
0
0
64
142
4.63
26.95
1.7
1.8
—
—
—
0
0
33
9
37.26
26.18
1.3
1.3
—
—
—
0
0
646
4402
1.70
24.84
2.5
2.1
148.3
245.0
u/l
2.33
622
4146
59
134
4.51
24.15
1.1
1.1
480.0
270.2
mg/l
2.13
51
112
386
2282
1.86
24.10
1.9
1.8
—
—
—
0
0
376
2231
1.85
23.11
2.1
2.2
29.2
29.7
s
0.83
366
2160
119
444
2.79
22.81
1.3
1.1
—
—
—
0
0
57
133
4.38
22.56
1.1
1.1
—
—
—
0
0
1017
7904
1.60
22.46
6.8
6.1
10.3
11.3
umol/l
2.39
966
7507
48
98
5.00
22.32
1.8
2.5
0.2
0.2
e9/l
0.01
40
84
51
111
4.69
22.00
1.2
1.1
1.2
1.1
u/l
0.99
25
61
40
70
5.81
21.98
1.2
1.2
—
—
—
0
0
48
103
4.75
21.07
1.8
2.5
548.6
574.4
e6/l
0.09
40
85
25
27
9.36
20.88
1.1
1.1
—
—
—
0
0
1098
8834
1.56
19.80
5.6
4.9
6.6
6.6
mmol/l
0.39
1041
8243
114
459
2.58
18.82
2.8
1.6
0.2
0.2
g/l
1.17
104
435
25
31
8.15
18.77
1.1
1.0
12.1
8.1
mg/g
0.94
25
31
929
7302
1.52
17.92
7.8
6.8
1.2
1.2
mmol/l
1.49
793
6189
23
8
29.06
17.42
1.0
1.0
—
—
—
0
0
1106
9064
1.51
17.19
10.5
8.9
4.2
4.1
e9/l
1.31
993
7951
851
6616
1.51
16.98
7.1
6.1
1.2
1.2
mmol/l
2.20
785
6017
23
9
25.83
16.91
1.2
1.0
—
—
—
0
0
113
478
2.45
16.82
2.9
1.5
1.2
1.2
g/l
0.00
103
450
21
7
30.30
16.11
1.0
1.0
—
—
—
0
0
644
4777
1.52
15.76
2.7
2.5
57.9
56.8
u/l
0.06
600
4432
43
108
4.05
15.52
1.6
2.0
10.5
12.8
%
0.71
22
52
815
6370
1.48
15.35
5.6
4.9
35.5
36.0
g/l
1.34
766
5966
727
5568
1.49
15.08
3.4
3.4
23.6
47.0
ng/l
2.53
469
3611
45
120
3.81
14.97
2.0
2.5
651.3
762.2
e6/l
0.50
25
45
188
1022
1.93
14.82
1.9
1.6
—
—
—
0
0
261
1575
1.76
14.71
1.8
1.7
—
—
—
0
0
115
525
2.27
14.42
2.1
1.7
—
—
—
0
0
261
1586
1.75
14.34
1.8
1.8
—
—
—
0
0
40
102
3.98
14.16
1.8
2.1
—
—
—
0
0
21
31
6.84
13.58
1.4
1.3
—
—
—
0
0
73
285
2.62
12.88
1.7
1.5
—
—
—
0
0
25
47
5.37
12.77
2.0
2.9
—
—
—
0
0
17
21
8.16
12.76
1.4
1.2
—
—
—
0
0
99
447
2.28
12.76
1.9
1.7
—
—
—
0
0
1351
11871
1.46
12.48
9.5
7.3
77.5
77.4
u/l
0.01
1302
11193
1167
10004
1.42
12.20
5.9
4.2
2959.0
2025.2
e6/l
0.15
21
140
257
1624
1.67
12.15
8.2
8.7
1.0
1.2
mmol/l
0.27
208
1263
17
23
7.45
11.84
1.2
2.5
—
—
—
0
0
111
550
2.08
11.36
2.4
2.1
1.0
1.8
ug/l
0.71
100
487
253
1628
1.64
11.11
8.2
8.7
5.1
5.1
kpa
0.14
242
1557
253
1628
1.64
11.11
8.2
8.7
12.8
12.3
kpa
0.77
242
1559
97
461
2.16
11.06
1.4
1.3
—
—
—
0
0
1300
11456
1.41
10.95
5.1
4.0
11.7
11.2
mm/h
0.73
1239
10669
112
578
1.99
10.28
2.1
1.9
—
—
—
0
0
341
2392
1.52
10.26
3.8
3.7
0.8
0.8
mmol/l
0.29
323
2250
142
796
1.85
10.18
1.6
1.6
—
—
—
0
0
206
1286
1.67
10.15
7.9
7.9
8.1
9.1
mmol/l
1.59
200
1226
286
1946
1.55
9.87
6.6
6.0
1.0
1.0
mmol/l
1.04
274
1805
91
442
2.11
9.85
2.8
3.0
—
—
—
0
0
72
318
2.31
9.83
2.0
3.2
30.8
34.4
umol/l
1.03
63
275
72
323
2.28
9.49
5.8
6.1
477.4
403.8
iu/ml
0.14
12
44
382
2785
1.46
9.43
3.6
3.5
195.1
481.0
ng/l
2.46
262
2048
89
438
2.08
9.32
2.0
2.2
10.4
11.3
mg/l
0.55
84
405
228
1504
1.58
8.99
2.7
2.1
351.9
371.2
nmol/l
0.75
214
1382
209
1351
1.61
8.97
9.4
9.6
120.6
122.5
g/l
0.71
200
1302
76
358
2.17
8.92
1.6
1.8
—
—
—
0
0
152
911
1.72
8.71
10.6
7.9
25.1
24.5
mmol/l
1.33
141
848
252
1725
1.53
8.42
20.0
22.3
1.3
1.3
inr
0.05
34
243
234
1576
1.55
8.41
3.5
4.4
227.4
246.5
u/l
1.56
220
1497
59
257
2.34
8.35
1.4
1.6
—
—
—
0
0
91
474
1.96
8.18
3.0
1.9
—
—
—
0
0
72
347
2.12
8.00
1.7
1.8
—
—
—
0
0
130
766
1.75
7.93
10.9
12.4
—
—
—
0
0
92
492
1.91
7.68
2.4
2.4
664.1
460.0
ug/l
0.25
83
463
336
2486
1.42
7.53
3.1
2.7
1.2
1.3
e6/l
0.07
186
1389
27
82
3.32
7.52
1.3
1.1
1785.8
1587.2
miu/ml
0.31
27
82
75
380
2.01
7.32
1.3
1.3
—
—
—
0
0
12
19
6.35
7.24
1.2
2.8
—
—
—
0
0
747
6292
1.30
7.16
2.6
2.3
76.9
75.9
nmol/l
0.48
676
5702
453
3565
1.35
6.96
1.7
1.8
1.1
1.1
mg/l
0.05
341
2682
1218
10968
1.30
6.87
3.8
3.1
52.7
47.5
u/l
1.09
1164
10326
107
623
1.76
6.83
1.4
1.2
0.3
1.1
u/ml
—
9
50
139
873
1.64
6.72
1.5
1.5
—
—
—
0
0
80
428
1.91
6.71
1.5
1.2
43.7
30.6
u/ml
—
8
23
698
5869
1.30
6.65
2.0
1.9
98.9
95.8
pmol/l
0.76
362
3109
633
5267
1.30
6.50
3.7
3.3
33.0
32.4
u/l
0.14
601
5016
421
3320
1.34
6.31
4.7
3.7
1.0
1.0
kg/l
1.00
74
467
74
398
1.89
6.13
1.5
1.2
5.3
10.2
u/ml
0.53
17
63
504
4101
1.31
6.04
4.0
3.0
0.3
0.4
e6/l
2.00
383
3070
395
3108
1.34
5.98
3.5
2.5
5.7
5.9
e6/l
0.09
360
2741
115
711
1.66
5.94
1.9
2.0
37.9
39.7
u/l
0.51
102
637
308
2340
1.38
5.84
3.4
2.9
2.5
2.6
e6/l
0.05
159
1245
58
292
2.02
5.83
1.3
1.3
—
—
—
0
0
58
292
2.02
5.83
1.3
1.3
—
—
—
0
0
191
1334
1.48
5.78
3.8
3.7
1.7
2.0
mmol/l
0.59
166
1069
831
7235
1.26
5.73
4.1
3.9
—
—
—
0
0
72
393
1.86
5.72
1.5
1.2
5.9
2.6
u/ml
—
10
38
1671
15864
1.39
5.70
19.7
13.1
22.5
22.9
mg/l
0.22
1418
12417
52
254
2.08
5.67
1.3
1.1
—
—
—
0
0
866
7622
1.25
5.29
4.5
3.4
0.0
0.0
estimate
0.50
145
1432
112
711
1.61
5.24
5.2
4.0
24.0
24.2
mmol/l
0.27
97
649
114
728
1.60
5.20
7.5
11.5
24.2
24.5
mmol/l
0.63
108
688
60
319
1.91
5.20
1.4
1.4
—
—
—
0
0
329
2570
1.34
5.19
1.9
1.7
1185.0
1188.6
nmol/l
0.02
262
1961
57
298
1.94
5.19
1.4
1.2
1.0
5.3
u/ml
—
5
24
153
1048
1.50
5.11
1.4
1.3
155.3
208.7
u/ml
0.45
146
963
96
594
1.65
4.98
8.2
6.6
1.7
1.6
%
0.51
89
556
243
1825
1.38
4.93
7.2
7.3
103.7
104.3
mmol/l
1.08
234
1783
871
7719
1.23
4.85
4.5
3.5
0.0
0.0
estimate
1.32
148
1392
50
257
1.97
4.80
1.9
1.9
—
—
—
0
0
45
223
2.04
4.78
1.4
1.5
—
—
—
0
0
863
7652
1.23
4.75
6.0
4.7
0.0
0.0
estimate
0.50
152
1460
444
3658
1.28
4.69
2.6
2.3
—
—
—
0
0
26
103
2.54
4.63
1.7
2.1
—
—
—
0
0
198
1460
1.40
4.49
2.5
2.4
31.8
71.7
u/l
0.65
173
1244
207
1539
1.39
4.47
2.3
2.7
1.7
1.8
%
0.39
186
1388
189
1390
1.40
4.36
2.4
2.3
0.2
0.2
g/l
0.34
179
1308
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
75
452
1.69
4.34
3.1
3.2
0.3
0.4
u/ml
0.19
43
249
15
45
3.35
4.32
1.3
1.1
—
—
—
0
0
10
22
4.56
4.30
1.1
1.0
—
—
—
0
0
59
335
1.78
4.22
1.4
1.2
21.0
44.4
u/ml
1.08
12
31
581
4998
1.23
4.14
3.6
3.4
2.3
2.4
mmol/l
0.82
508
4420
29
128
2.28
4.13
1.6
1.6
—
—
—
0
0
29
128
2.28
4.13
1.6
1.6
—
—
—
0
0
29
128
2.28
4.13
1.6
1.6
—
—
—
0
0
94
608
1.57
4.13
4.8
4.0
24.7
24.9
mmol/l
0.27
87
570
136
952
1.46
4.12
4.9
3.6
5.2
5.2
kpa
0.02
128
896
27
117
2.33
4.01
1.3
1.2
—
—
—
0
0
20
75
2.68
3.99
1.7
1.9
—
—
—
0
0
20
75
2.68
3.99
1.7
1.9
—
—
—
0
0
20
75
2.68
3.99
1.6
1.9
—
—
—
0
0
20
75
2.68
3.99
1.7
1.9
—
—
—
0
0
1300
12129
1.22
3.97
4.4
3.9
14.7
14.7
pmol/l
0.03
1196
11150
36
177
2.05
3.95
1.5
1.5
—
—
—
0
0
27
118
2.31
3.94
1.3
1.2
—
—
—
0
0
34
164
2.09
3.92
2.4
6.8
7.8
7.0
mmol/l
0.21
22
137
103
689
1.52
3.91
2.8
2.5
1.1
1.3
%
0.74
103
684
677
5950
1.21
3.85
4.7
3.6
—
—
—
0
0
129
907
1.45
3.84
4.9
3.7
1.3
1.7
mmol/l
0.66
99
668
71
437
1.65
3.83
1.4
1.5
266.0
289.4
ug/g
0.48
41
244
38
194
1.98
3.78
1.5
1.5
—
—
—
0
0
35
174
2.03
3.75
1.5
1.5
—
—
—
0
0
35
174
2.03
3.75
1.5
1.5
—
—
—
0
0
35
174
2.03
3.75
1.5
1.5
—
—
—
0
0
35
175
2.02
3.69
1.5
1.5
—
—
—
0
0
227
1768
1.32
3.65
2.7
2.7
6.7
7.9
umol/l
0.58
191
1537
49
276
1.80
3.64
1.2
1.1
—
10.1
—
0
18
134
960
1.42
3.62
3.2
3.3
4.4
4.6
pmol/l
0.57
114
844
33
163
2.04
3.60
1.2
1.2
—
—
—
0
0
35
177
1.99
3.59
1.5
1.5
—
—
—
0
0
14
46
3.06
3.53
3.4
2.7
—
—
—
0
0
14
46
3.06
3.53
3.4
2.7
—
—
—
0
0
155
1145
1.38
3.52
2.7
2.7
66.6
66.9
g/l
0.12
143
1057
370
3080
1.25
3.51
1.6
1.7
65361890.3
33372384.5
pmol/l
0.28
332
2589
82
535
1.56
3.51
1.8
1.8
—
—
—
0
0
23
99
2.34
3.50
1.3
1.1
—
—
—
0
0
56
333
1.70
3.47
5.1
4.0
55.7
57.3
%
0.36
56
333
273
2195
1.28
3.46
1.7
1.8
1.5
1.4
%
0.17
241
1951
90
603
1.52
3.43
1.5
2.0
1.6
1.5
g/l
0.15
80
529
454
3881
1.22
3.35
2.9
3.0
1254.3
1226.6
ng/l
0.03
385
3278
49
284
1.74
3.33
1.7
1.5
—
—
—
0
0
54
322
1.70
3.32
4.7
3.7
3.8
4.2
e9/l
0.55
54
322
390
3291
1.23
3.26
1.5
1.5
21.9
20.8
nmol/l
0.72
332
2832
123
886
1.41
3.25
2.9
3.1
125.9
130.4
g/l
1.57
123
866
13
43
3.04
3.25
2.1
1.9
—
—
—
0
0
21
90
2.35
3.24
1.1
1.0
229.6
291.7
ng/l
0.46
12
55
16
60
2.68
3.22
1.8
2.0
—
—
—
0
0
16
60
2.68
3.22
1.8
2.0
—
—
—
0
0
11
33
3.35
3.19
1.1
1.0
—
—
—
0
0
21
91
2.32
3.17
1.1
1.0
697.4
739.9
ng/l
0.16
13
55
21
91
2.32
3.17
1.1
1.0
33.9
42.9
ng/l
—
10
53
16
61
2.64
3.13
1.8
2.0
—
—
—
0
0
470
4066
1.21
3.05
5.1
3.8
0.0
0.0
estimate
1.28
139
1421
7
12
5.85
3.02
1.3
1.2
—
—
—
0
0
9
21
4.30
2.99
1.1
1.0
—
—
—
0
0
1664
16067
1.25
2.97
20.5
14.7
139.5
139.6
mmol/l
2.11
1639
15664
1170
10946
1.17
2.96
3.3
3.1
—
—
—
0
0
460
3983
1.20
2.95
2.8
2.6
1449.8
5154.6
umol/l
2.31
412
3506
432
3723
1.21
2.91
2.3
2.1
3.0
2.9
mg/l
0.06
377
3179
248
2015
1.26
2.90
2.6
2.5
132.4
120.6
ug/g
0.29
202
1612
256
2089
1.26
2.89
2.8
2.4
2.3
2.3
g/l
0.10
245
1940
9
22
4.10
2.88
2.3
2.4
—
—
—
0
0
9
22
4.10
2.88
1.2
1.0
—
—
—
0
0
67
439
1.54
2.87
6.1
4.0
3.9
3.9
mmol/l
0.12
62
409
6
9
6.68
2.87
1.8
5.2
—
—
—
0
0
18
77
2.35
2.82
1.3
1.4
—
—
—
0
0
18
77
2.35
2.82
1.3
1.4
—
—
—
0
0
51
316
1.63
2.77
2.1
2.3
131.2
130.1
g/l
0.08
32
239
43
255
1.70
2.75
4.5
5.5
358.1
373.3
umol/l
0.31
36
224
39
227
1.73
2.67
3.9
3.5
0.7
1.5
%
1.39
33
187
762
6935
1.16
2.65
3.0
2.8
112.3
119.4
ug/l
0.45
709
6454
33
184
1.81
2.61
1.2
1.3
—
—
—
0
0
5
7
7.15
2.55
1.0
1.0
—
—
—
0
0
1664
16121
1.23
2.53
20.5
14.8
4.0
4.0
mmol/l
0.23
1635
15688
218
1775
1.26
2.52
7.8
6.6
—
—
—
0
0
143
1104
1.32
2.50
4.1
3.9
78.9
83.4
ng/l
0.35
125
975
68
463
1.49
2.48
2.1
1.7
—
—
—
0
0
36
211
1.72
2.43
1.6
1.8
—
—
—
0
0
30
168
1.80
2.37
1.8
2.0
—
—
—
0
0
154
1212
1.29
2.36
2.3
2.3
6.0
7.2
ug/l
0.49
132
1084
1539
14834
1.18
2.31
15.3
11.8
85.8
84.6
ml/min/173m2
1.32
1332
12197
48
309
1.57
2.28
1.6
1.4
99.9
116.7
u/ml
—
7
64
13
53
2.46
2.27
1.5
1.2
—
—
—
0
0
24
127
1.90
2.26
1.2
1.5
0.7
1.3
promille
1.52
19
102
270
2279
1.21
2.25
2.8
2.5
12.9
13.6
umol/l
0.66
259
2112
87
635
1.39
2.22
3.6
3.6
50.2
49.3
%
0.12
87
626
233
1945
1.22
2.17
2.9
2.5
22.5
23.4
%
0.37
202
1673
307
2633
1.20
2.17
1.3
1.3
6.8
11.4
u/ml
1.01
116
1055
75
536
1.41
2.16
1.3
1.3
—
—
—
0
0
33
197
1.69
2.12
1.5
1.7
—
—
—
0
0
139
1098
1.29
2.10
2.8
2.9
166.3
192.4
ng/l
0.36
120
999
320
2766
1.19
2.07
1.4
1.3
24.8
29.2
iu/ml
0.33
104
873
50
333
1.51
2.07
1.3
1.6
—
—
—
0
0
5
10
5.01
2.07
1.8
1.2
—
—
—
0
0
141
1120
1.28
2.04
1.2
1.2
92.8
145.8
iu/ml
1.05
51
436
58
401
1.46
2.01
1.3
1.4
—
—
—
0
0
14
63
2.23
2.01
1.1
1.3
—
—
—
0
0
72
519
1.40
2.00
1.5
1.6
0.1
0.1
iu/ml
0.10
19
86
215
1799
1.22
1.97
4.7
4.2
32.0
31.6
%
0.15
141
1251
71
512
1.40
1.97
2.9
2.4
3.5
3.7
g/l
0.80
44
380
158
1279
1.26
1.97
2.4
2.3
12.6
13.1
nmol/l
0.32
140
1143
65
462
1.42
1.96
1.2
1.2
—
—
—
0
0
71
513
1.40
1.95
2.9
2.4
7.1
7.3
g/l
0.38
48
398
71
513
1.40
1.95
2.9
2.4
—
—
—
0
0
12
51
2.36
1.95
2.3
1.9
95.5
61.4
ug/l
0.45
12
51
72
522
1.39
1.94
1.8
1.4
10.2
8.8
u/l
0.40
62
427
51
348
1.48
1.91
1.7
1.6
12218.3
12127.0
e6/l
0.01
44
261
42
275
1.54
1.90
1.3
1.2
2.5
3.0
u/ml
0.16
17
85
62
440
1.42
1.89
3.2
2.6
1.2
0.9
g/l
0.21
54
396
41
269
1.54
1.85
2.9
3.9
126.3
1421.1
u/ml
0.79
36
258
24
137
1.76
1.83
3.3
3.5
55.8
54.9
%
0.08
17
97
75
555
1.37
1.81
1.3
1.3
163.1
222.0
miu/ml
1.01
36
267
1474
14240
1.15
1.81
5.6
5.3
39.5
39.4
mmol/mol
0.22
1377
13282
9
35
2.58
1.80
1.6
1.3
—
—
—
0
0
51
353
1.46
1.79
1.3
1.3
—
—
—
0
0
64
464
1.39
1.75
1.2
1.2
—
—
—
0
0
356
3149
1.16
1.74
1.7
1.5
—
—
—
0
0
21
117
1.80
1.74
1.9
1.8
—
—
—
0
0
408
3647
1.15
1.73
1.3
1.3
2.3
1.7
u/ml
0.27
107
992
1491
14429
1.14
1.73
5.2
4.6
1.8
2.0
mu/l
1.13
1385
13332
26
155
1.69
1.72
1.2
1.2
60.4
55.0
u/l
0.22
20
111
65
476
1.38
1.69
2.6
2.4
10.1
10.4
g/l
0.14
52
412
20
111
1.81
1.68
1.1
1.5
—
—
—
0
0
10
42
2.39
1.67
1.0
1.2
—
—
—
0
0
12
55
2.19
1.67
1.2
1.3
—
—
—
0
0
85
651
1.32
1.66
1.9
1.6
272.8
298.5
mu/l
0.57
78
593
23
134
1.72
1.66
2.7
2.5
—
—
—
0
0
13
62
2.10
1.65
1.3
1.4
—
—
—
0
0
13
62
2.10
1.65
1.3
1.4
—
—
—
0
0
7
25
2.81
1.65
1.3
1.2
—
—
—
0
0
28
173
1.63
1.64
1.9
2.3
19.9
25.6
mg/l
—
8
50
40
270
1.49
1.61
1.3
1.2
8.6
5.2
u/ml
0.50
17
109
168
1408
1.21
1.56
3.9
4.2
10.8
19.7
ug/l
0.44
125
1144
1725
16905
1.18
1.55
13.0
9.9
28.0
27.2
u/l
0.74
1685
16382
65
484
1.35
1.55
2.8
2.4
2.9
3.1
g/l
0.55
46
387
38
257
1.49
1.53
1.1
1.1
—
—
—
0
0
298
2634
1.15
1.49
3.4
3.0
2.4
2.4
mmol/l
0.11
266
2321
57
419
1.37
1.48
2.9
3.5
31.3
39.3
mg/l
0.46
45
327
68
516
1.33
1.45
4.0
3.6
490.7
2804.4
u/ml
0.62
58
438
12
60
2.01
1.38
2.1
2.5
—
—
—
0
0
69
531
1.31
1.35
2.1
2.4
92.7
93.0
%
0.03
64
495
56
419
1.35
1.33
2.9
3.5
44.1
65.5
mg/l
0.66
44
326
53
395
1.35
1.29
2.5
2.5
0.0
0.0
g/l
0.29
48
368
13
69
1.89
1.28
2.2
1.5
430361.7
1290600.0
iu/ml
—
6
5
34
236
1.45
1.25
1.2
1.2
—
—
—
0
0
36
253
1.43
1.24
1.4
1.4
20.9
23.6
u/l
0.27
30
206
28
187
1.50
1.24
2.6
2.2
9.0
6.0
umol/l
0.63
20
133
145
1230
1.19
1.23
3.2
2.5
64.1
69.8
ml/min/173m2
0.97
55
482
27
180
1.51
1.21
1.5
1.7
53.0
57.9
%
0.23
21
122
17
101
1.69
1.19
2.0
1.5
8.3
8.3
u/l
0.00
12
50
499
4620
1.11
1.18
3.5
3.2
7.8
7.8
mmol/l
0.04
424
3929
6
26
2.31
1.18
1.0
1.5
—
—
—
0
0
41
299
1.38
1.16
3.1
2.5
16.6
16.3
%
0.15
21
150
174
1509
1.17
1.15
3.6
3.2
—
—
—
0
0
18
110
1.64
1.15
1.4
1.1
1.1
1.0
ratio
—
9
45
19
118
1.62
1.14
1.4
1.2
—
—
—
0
0
53
404
1.32
1.14
2.1
2.4
36.9
38.0
g/l
0.52
44
358
45
337
1.34
1.10
1.4
1.3
253.9
254.0
u/ml
0.00
31
210
19
289
0.65
1.05
1.7
1.5
—
—
—
0
0
99
828
1.21
1.01
1.6
1.4
25.3
26.7
iu/l
0.16
88
704
19
124
1.54
0.96
1.2
1.3
68052.3
130677.3
e6/l
0.41
14
71
237
2133
1.13
0.95
2.3
2.1
—
—
—
0
0
79
653
1.22
0.93
2.2
2.2
1286.7
4285.2
u/l
1.91
29
252
19
127
1.50
0.88
1.4
1.4
—
—
—
0
0
24
335
0.71
0.88
1.9
1.7
—
—
—
0
0
11
64
1.72
0.86
5.6
2.1
0.9
1.4
ug/l
0.74
11
58
12
73
1.65
0.81
2.8
3.1
—
—
—
0
0
214
1936
1.12
0.81
2.2
2.0
—
—
—
0
0
106
914
1.17
0.81
2.4
1.8
—
—
—
0
0
135
1188
1.15
0.79
5.6
3.7
1.2
1.2
mmol/l
2.51
125
1030
40
313
1.28
0.78
3.0
2.8
1.5
1.6
mmol/l
0.21
40
303
13
82
1.59
0.78
1.8
1.8
—
—
—
0
0
13
82
1.59
0.78
1.8
1.8
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
9
53
1.70
0.75
1.1
1.9
—
—
—
0
0
5
24
2.09
0.74
9.2
5.5
—
—
—
0
0
19
133
1.43
0.73
2.4
2.3
—
—
—
0
0
35
272
1.29
0.73
1.1
1.1
—
—
—
0
0
9
57
1.58
0.71
1.0
1.1
—
—
—
0
0
35
274
1.28
0.69
1.1
1.1
118.4
123.4
iu/ml
—
8
69
9
58
1.55
0.69
2.7
4.8
—
—
—
0
0
46
373
1.24
0.69
6.0
2.9
24.8
24.9
mmol/l
0.04
40
331
149
1656
0.89
0.68
1.7
1.7
—
—
—
0
0
5
28
1.79
0.66
2.0
1.6
—
—
—
0
0
14
200
0.70
0.63
1.0
1.1
—
—
—
0
0
8
52
1.54
0.59
1.0
1.0
—
—
—
0
0
8
52
1.54
0.59
2.3
1.4
10.6
8.8
ug/l
—
8
52
58
681
0.85
0.59
1.9
1.7
6.4
4.7
mg/l
0.24
43
478
14
97
1.45
0.59
1.1
1.5
5.2
6.6
u/l
—
9
77
15
106
1.42
0.57
1.0
1.1
8.6
10.7
iu/ml
—
5
26
62
531
1.17
0.56
1.5
1.4
—
—
—
0
0
16
115
1.39
0.56
1.1
1.1
—
—
—
0
0
16
115
1.39
0.56
1.1
1.1
—
—
—
0
0
11
73
1.51
0.56
1.1
1.1
—
—
—
0
0
16
116
1.38
0.54
1.1
1.1
—
—
—
0
0
16
116
1.38
0.54
1.1
1.1
—
—
—
0
0
16
116
1.38
0.54
1.1
1.1
—
—
—
0
0
6
38
1.58
0.54
2.0
2.1
23.0
17.3
umol/l
—
6
38
14
99
1.42
0.54
1.1
1.2
—
—
—
0
0
98
874
1.13
0.53
1.3
1.4
—
—
—
0
0
44
370
1.19
0.51
2.2
2.5
0.0
0.0
g/l
0.00
39
344
20
154
1.30
0.48
1.1
1.0
—
—
—
0
0
55
475
1.16
0.48
2.7
2.8
3.9
3.6
g/l
0.64
55
451
18
140
1.29
0.42
4.2
3.8
—
—
—
0
0
5
33
1.52
0.41
5.6
1.6
1.2
1.2
mmol/l
—
5
33
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
13
97
1.34
0.39
1.8
1.7
—
—
—
0
0
455
4385
1.05
0.38
4.3
4.0
17.7
8.8
mg/mmol
1.52
295
2791
126
1165
1.09
0.38
2.5
1.9
—
—
—
0
0
31
261
1.19
0.38
1.2
1.0
2.2
2.4
u/ml
—
10
123
272
2589
1.06
0.37
1.5
1.4
—
—
—
0
0
17
134
1.27
0.37
1.3
1.4
1.2
1.5
nmol/l
0.74
17
120
40
347
1.16
0.35
1.9
2.2
0.8
0.9
nmol/l
0.06
33
298
6
43
1.40
0.35
1.0
1.1
—
—
—
0
0
45
395
1.14
0.35
1.6
2.0
2.8
5.0
iu/l
2.34
16
139
6
44
1.36
0.34
1.2
1.2
331.8
292.1
pmol/l
—
6
28
34
293
1.16
0.33
3.1
2.9
8.0
7.3
mmol/l
0.48
34
286
31
265
1.17
0.33
1.5
1.5
0.3
0.3
nmol/l
0.01
22
213
72
791
0.91
0.33
1.6
1.5
—
—
—
0
0
34
392
0.86
0.33
1.6
1.5
—
—
—
0
0
46
407
1.13
0.32
2.0
1.9
196.6
202.7
pmol/l
0.15
46
383
13
101
1.29
0.31
1.4
1.3
—
—
—
0
0
19
229
0.83
0.30
1.5
1.6
—
—
—
0
0
10
75
1.33
0.30
1.1
1.9
—
—
—
0
0
10
75
1.33
0.30
1.1
1.9
—
—
—
0
0
13
102
1.28
0.30
1.2
1.9
—
—
—
0
0
94
872
1.08
0.29
1.0
1.0
—
—
—
0
0
5
74
0.67
0.26
1.0
1.1
110.2
207.7
iu/ml
—
5
74
70
646
1.09
0.25
1.1
1.1
—
0.9
—
0
10
15
123
1.22
0.25
1.1
1.3
0.2
0.6
u/ml
—
10
55
40
361
1.11
0.23
2.3
2.4
48.0
115.9
ug/min
1.77
20
227
12
97
1.24
0.22
1.0
1.0
—
—
—
0
0
7
93
0.75
0.22
2.6
1.9
—
—
—
0
0
19
220
0.86
0.21
1.1
1.0
0.1
0.5
u/ml
—
5
54
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
14
117
1.20
0.20
1.7
1.9
—
—
—
0
0
1484
14934
0.97
0.20
18.6
13.8
39.7
40.3
%
1.58
1119
11256
358
3670
0.97
0.20
3.9
3.9
20.9
21.2
%
0.13
156
1580
1526
15162
1.03
0.19
4.4
4.2
5.9
5.9
mmol/l
0.36
1405
13929
17
146
1.17
0.19
3.1
4.5
14.9
90.9
u/ml
—
7
42
7
61
1.15
0.17
1.4
1.1
0.3
0.3
g/l
—
7
50
27
243
1.11
0.17
3.1
3.1
0.7
0.9
nmol/l
0.58
19
195
23
257
0.89
0.17
1.0
1.0
5.7
3.0
u/ml
0.39
11
94
24
215
1.12
0.16
1.3
1.3
0.5
0.6
nmol/l
0.58
24
205
27
298
0.90
0.16
1.6
1.7
—
—
—
0
0
22
197
1.12
0.15
1.0
1.2
—
—
—
0
0
9
81
1.11
0.15
1.4
2.0
—
—
—
0
0
8
96
0.83
0.13
1.4
1.5
—
—
—
0
0
44
412
1.07
0.13
1.3
1.4
—
—
—
0
0
44
412
1.07
0.13
1.3
1.4
—
—
—
0
0
44
413
1.07
0.13
1.3
1.4
—
—
—
0
0
44
414
1.06
0.12
1.3
1.4
—
—
—
0
0
263
2683
0.98
0.12
2.9
2.8
0.6
0.7
ug/l
1.22
169
1628
12
136
0.88
0.11
1.4
1.4
10.6
12.7
mmol/l
—
5
33
12
135
0.89
0.10
1.2
1.4
—
—
—
0
0
1504
14985
1.02
0.09
3.9
3.8
1.4
1.3
mmol/l
1.90
1409
13873
6
56
1.07
0.08
1.3
1.6
—
—
—
0
0
33
349
0.94
0.08
1.2
1.1
0.2
1.9
u/ml
2.92
17
147
41
390
1.05
0.08
1.3
1.2
—
—
—
0
0
11
123
0.89
0.08
8.2
15.1
521.6
809.6
nmol/l
1.28
11
118
14
127
1.10
0.07
1.1
1.1
—
—
—
0
0
12
108
1.11
0.07
1.2
1.2
—
—
—
0
0
10
111
0.90
0.06
1.7
1.7
—
—
—
0
0
19
178
1.07
0.05
2.1
2.3
34.2
32.1
pg
1.75
19
178
1567
15639
1.01
0.04
4.3
4.2
4.7
4.7
mmol/l
0.33
1467
14630
16
170
0.94
0.04
1.2
1.1
—
—
—
0
0
1585
15870
0.99
0.04
4.7
4.6
2.8
2.8
mmol/l
0.00
1470
14747
1553
15549
0.99
0.03
4.3
4.2
1.4
1.5
mmol/l
0.21
1444
14459
46
449
1.02
0.03
1.4
1.5
—
—
—
0
0
1784
17821
1.01
0.03
26.6
19.1
253.8
253.0
e9/l
0.18
1757
17416
33
321
1.03
0.02
5.3
3.6
23.6
24.0
mg/l
0.02
19
211
1339
13401
1.00
0.01
21.0
15.8
13.7
13.6
%
1.16
1322
13107
66
651
1.01
0.01
1.7
1.8
—
—
—
0
0
460
4586
1.00
0.01
4.9
4.4
2.6
2.3
ug/l
0.18
420
4134
1785
17836
1.01
0.01
26.5
19.1
4.5
4.5
e12/l
1.68
1752
17388
52
513
1.01
0.01
1.3
1.4
—
—
—
0
0
12
126
0.95
0.01
1.2
1.5
0.9
1.0
g/l
0.76
12
126
22
221
1.00
0.00
2.2
2.9
3.3
77.7
u/ml
0.70
22
209
18
185
0.97
0.00
1.1
1.1
—
—
—
0
0
55
548
1.00
0.00
1.5
1.4
—
—
—
0
0
410
4096
1.00
0.00
1.6
1.6
1.5
1.4
mmol/l
0.80
357
3487
1785
17842
1.00
0.00
26.6
19.1
6.9
6.7
e9/l
2.49
1756
17396
1785
17842
1.00
0.00
26.7
19.2
135.4
136.6
g/l
3.23
1771
17613
22
215
1.02
0.00
1.3
1.4
6.8
7.3
mmol/l
0.26
15
156
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
5.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
2.0
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint MENINGITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| MENINGITIS | 2.303 [1.99, 2.66] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.211 |
During the follow-up period (1.1.1998 — 31.12.2019), 686 out of 3805 females with MENINGITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| MENINGITIS | 2.327 [2.0, 2.71] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 823 out of 3963 males with MENINGITIS died.
Mortality risk
Mortality risk for people of age
years, who have MENINGITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.233% | 0.438% |
| 5 | 1.237% | 2.553% |
| 10 | 3.441% | 6.493% |
| 15 | 6.682% | 11.706% |
| 20 | 10.829% | 19.098% |
Relationships between endpoints
↥Index endpoint: MENINGITIS – Meningitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data