viral meningitis: Viral infections of the leptomeninges and subarachnoid space. TOGAVIRIDAE INFECTIONS; FLAVIVIRIDAE INFECTIONS; RUBELLA; BUNYAVIRIDAE INFECTIONS; ORBIVIRUS infections; PICORNAVIRIDAE INFECTIONS; ORTHOMYXOVIRIDAE INFECTIONS; RHABDOVIRIDAE INFECTIONS; ARENAVIRIDAE INFECTIONS; HERPESVIRIDAE INFECTIONS; ADENOVIRIDAE INFECTIONS; JC VIRUS infections; and RETROVIRIDAE INFECTIONS may cause this form of meningitis. Clinical manifestations include fever, headache, neck pain, vomiting, PHOTOPHOBIA, and signs of meningeal irritation. (From Joynt, Clinical Neurology, 1996, Ch26, pp1-3)
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
170 |
4. Check minimum number of eventsNone |
170 |
5. Include endpointsNone |
170 |
6. Filter based on genotype QC (FinnGen only) |
164 |
Control definitions (FinnGen only)
- Control exclude
- G6_NEUINFL
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF12
Similar endpoints
↥List of similar endpoints to
Meningitis, viral
based on the number of shared cases.
Similar with more cases:
- Meningitis
- Inflammatory diseases of the central nervous system
- Certain infectious and parasitic diseases
- Neurological diseases
- Neurological diseases, wide definition
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1037 | 609 | 424 |
| Only index persons | 980 | 583 | 397 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 36.25 | 39.74 | 31.18 |
| Only index persons | 36.97 | 39.99 | 32.53 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 164 | 119 | 45 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.02 |
| Median age at first event (years) | 45.78 | 43.26 | 52.43 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 170
- Matched controls
- 1700
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G02.0*B00.3
ICD-10 Finland
Herpesviral meningitis
+∞
104.2
89
*
A87.9
ICD-10 Finland
Viral meningitis, unspecified
205.6
73.8
72
6
J05AB11
ATC
valaciclovir; oral
9.7
49.7
87
166
TAB00
NOMESCO Finland
Lumbar puncture
14.0
44.0
46
44
G02.0*B02.1
ICD-10 Finland
Zoster meningitis
+∞
32.3
30
*
R51.80
ICD-10 Finland
Headache
6.0
29.2
78
212
G02.0*B01.0
ICD-10 Finland
Varicella meningitis
+∞
29.0
27
*
G02.0
ICD-10 Finland
Meningitis in viral diseases classified elsewhere
+∞
22.4
21
*
G03.9
ICD-10 Finland
Meningitis, unspecified
+∞
20.2
19
*
G02.0*A87.0
ICD-10 Finland
Enteroviral meningitis
+∞
20.2
19
*
AA1AD
NOMESCO Finland
CT of head and brain
4.4
19.4
70
232
A86
ICD-10 Finland
Unspecified viral encephalitis
+∞
15.9
15
*
J05AB01
ATC
aciclovir; systemic
3.8
15.7
73
283
B00.3
ICD-10 Finland
Herpesviral meningitis
+∞
14.8
14
*
G04.9
ICD-10 Finland
Encephalitis, myelitis and encephalomyelitis, unspecified
+∞
12.7
12
*
A87.8
ICD-10 Finland
Other viral meningitis
+∞
11.6
11
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.4
11.2
53
202
5AB01, ,
NOMESCO Finland
+∞
10.5
10
*
G05.1*B00.4
ICD-10 Finland
Herpesviral meningoencephalitis
+∞
10.5
10
*
N71
ICPC
Meningitis/encephalitis
+∞
9.5
9
*
H02AB06
ATC
prednisolone; systemic
2.7
9.1
96
554
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
8.5
81
442
XF400
NOMESCO Finland
ECG with 12 standard connections
3.4
8.4
34
116
B02.9
ICD-10 Finland
Zoster without complication
4.7
8.2
20
47
N01
ICPC
Headache
3.0
7.6
38
147
R51
ICD-10 Finland
Headache
4.4
7.6
20
50
ZX120
NOMESCO Finland
Intravenous
3.5
7.4
27
86
B02.1
ICD-10 Finland
Zoster meningitis
+∞
7.3
7
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.5
7.2
27
87
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
9.4
7.2
14
16
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
23.6
6.7
9
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.4
6.6
25
81
N03AX16
ATC
[U] pregabalin
2.6
6.6
49
232
A87.0
ICD-10 Finland
Enteroviral meningitis
72.5
6.5
7
*
J45.9
ICD-10 Finland
Asthma, unspecified
2.7
6.4
42
187
B00.4
ICD-10 Finland
Herpesviral encephalitis
+∞
6.3
6
*
G03.2
ICD-10 Finland
Benign recurrent meningitis [Mollaret]
+∞
6.3
6
*
R4110
NOMESCO Finland
Physiotherapy
2.4
6.0
53
271
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
55
36
22.11
66.19
1.5
1.3
166.93
2.96
e6/l
4.50
42
26
55
36
22.11
66.19
1.5
1.4
26.28
259.17
e6/l
0.77
43
29
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
47
5
128.64
45.48
1.4
1.2
—
—
—
0
0
46
8
78.01
41.80
1.4
1.3
—
—
—
0
0
24
5
55.46
20.77
1.3
1.0
—
—
—
0
0
27
15
21.13
18.50
1.4
1.1
—
—
—
0
0
22
7
35.77
17.52
1.5
1.1
2.52
1.65
mmol/l
—
22
7
24
15
18.39
15.78
1.4
1.1
—
—
—
0
0
21
9
26.38
15.54
1.3
1.2
—
—
—
0
0
21
14
16.91
13.50
1.4
1.0
—
—
—
0
0
22
19
13.11
12.74
1.3
1.2
—
—
—
0
0
15
7
23.32
10.89
1.3
1.0
90.44
—
%
—
9
0
16
12
14.57
9.89
1.6
1.7
—
—
—
0
0
21
45
5.18
9.59
1.3
1.1
—
—
—
0
0
13
9
15.50
8.35
1.1
1.2
—
—
—
0
0
31
100
3.57
8.33
1.5
1.2
—
43.96
—
0
5
13
10
13.95
8.02
1.6
1.6
—
—
—
0
0
12
8
16.01
7.84
3.3
2.6
324.25
764.38
u/ml
—
12
8
13
14
9.95
6.92
1.3
1.3
918.46
715.86
e6/l
0.57
13
14
11
9
12.96
6.68
1.8
1.9
—
—
—
0
0
33
129
2.93
6.43
1.5
1.7
—
—
—
0
0
36
151
2.76
6.15
2.2
1.9
28.66
29.70
s
0.68
36
146
115
809
2.30
6.03
9.5
9.1
4.04
4.04
e9/l
0.01
107
717
44
207
2.52
5.97
4.0
3.0
28.23
71.85
ng/l
0.70
26
126
12
16
7.98
5.74
1.1
1.3
—
—
—
0
0
16
42
4.10
5.68
1.4
1.4
—
—
—
0
0
9
7
13.48
5.65
1.1
1.0
—
—
—
0
0
31
128
2.74
5.43
1.6
1.6
—
—
—
0
0
5
0
+∞
5.23
1.4
0.0
—
—
—
0
0
39
186
2.42
5.09
2.6
2.5
3.94
3.28
e6/l
0.09
14
97
23
84
3.01
5.01
2.0
1.6
—
—
—
0
0
39
193
2.32
4.67
1.7
1.8
—
—
—
0
0
69
430
2.02
4.59
2.9
3.2
21.55
19.97
ng/l
0.11
33
247
18
60
3.24
4.55
1.4
1.6
—
—
—
0
0
69
436
1.98
4.37
3.6
2.9
—
—
—
0
0
52
302
2.04
4.14
1.5
1.7
0.59
0.68
mg/l
0.32
41
222
38
197
2.20
4.05
2.4
2.4
0.65
0.80
e6/l
0.18
13
108
12
29
4.37
3.78
1.2
1.3
—
—
—
0
0
12
29
4.37
3.78
1.2
1.3
—
—
—
0
0
21
87
2.61
3.64
1.6
1.2
99.70
139.60
u/ml
0.28
21
76
90
658
1.78
3.38
3.3
2.8
92.78
82.45
ug/l
0.33
85
618
8
14
5.94
3.38
1.0
1.1
—
—
—
0
0
132
1085
1.97
3.37
4.2
4.2
14.39
14.53
pmol/l
0.25
122
1005
6
7
8.83
3.29
1.7
1.0
2352.83
1531.71
miu/ml
—
6
7
15
55
2.89
3.25
1.9
1.5
—
—
—
0
0
54
344
1.84
3.18
3.2
2.6
0.11
0.43
e6/l
1.80
37
260
65
439
1.78
3.15
4.1
3.1
28.42
29.00
u/l
0.10
60
417
11
31
3.72
3.05
1.5
1.4
—
—
—
0
0
76
546
1.71
2.92
2.4
2.4
77.02
75.27
nmol/l
0.20
70
496
5
6
8.54
2.76
1.4
1.2
11.20
14.83
u/l
—
5
6
5
6
8.54
2.76
1.2
1.2
—
—
—
0
0
156
1395
2.44
2.71
19.1
11.9
14.53
20.32
mg/l
2.74
132
1084
12
41
3.07
2.68
4.3
14.8
1.53
1.47
%
0.08
12
36
10
30
3.48
2.65
1.3
1.7
45.70
41.82
nmol/l
—
10
30
69
502
1.63
2.42
9.4
10.9
1.16
1.16
inr
0.03
22
163
40
251
1.78
2.42
3.0
2.0
—
—
—
0
0
5
8
6.40
2.39
1.6
1.0
—
—
—
0
0
43
277
1.74
2.38
3.3
2.2
—
—
—
0
0
144
1283
1.80
2.04
5.2
4.8
1.81
1.83
mu/l
0.05
136
1192
5
11
4.65
1.95
1.0
1.1
—
—
—
0
0
5
11
4.65
1.95
1.0
1.1
—
—
—
0
0
58
423
1.56
1.95
3.0
3.2
2.32
2.34
mmol/l
0.79
52
379
12
52
2.41
1.92
4.6
3.4
25.31
24.71
mmol/l
0.21
12
52
9
34
2.74
1.89
1.1
2.5
—
—
—
0
0
23
134
1.83
1.77
3.6
1.8
—
—
—
0
0
19
105
1.91
1.71
4.1
10.7
4.94
5.08
kpa
0.30
19
98
19
105
1.91
1.71
4.1
10.7
13.11
12.22
kpa
0.40
19
98
8
31
2.66
1.68
1.0
1.2
—
—
—
0
0
49
356
1.53
1.65
1.7
1.7
—
—
—
0
0
14
70
2.09
1.64
1.1
1.3
—
—
—
0
0
124
1091
1.50
1.56
3.9
3.7
—
—
—
0
0
10
46
2.25
1.43
2.9
2.0
—
—
—
0
0
72
580
1.42
1.41
8.3
7.1
1.20
1.22
mmol/l
1.76
64
487
7
29
2.47
1.41
1.3
2.7
189.29
193.90
%
—
7
29
66
524
1.42
1.40
7.2
6.4
1.20
1.22
mmol/l
1.89
61
484
85
706
1.41
1.39
4.5
3.5
0.00
0.01
estimate
0.50
12
159
5
17
3.00
1.37
1.2
1.7
—
—
—
0
0
5
17
3.00
1.37
1.2
1.7
—
—
—
0
0
84
702
1.39
1.30
6.5
4.8
0.00
0.00
estimate
-0.00
13
151
46
346
1.45
1.29
1.2
1.3
0.54
1.05
u/ml
—
10
108
9
44
2.10
1.29
4.2
2.6
—
—
—
0
0
8
36
2.28
1.26
1.5
1.2
—
—
—
0
0
6
25
2.45
1.25
1.2
1.8
—
—
—
0
0
5
19
2.68
1.22
1.2
1.6
—
—
—
0
0
5
19
2.68
1.22
1.0
1.6
—
—
—
0
0
5
19
2.68
1.22
1.0
1.6
—
—
—
0
0
61
488
1.39
1.21
2.2
1.8
93.35
96.12
pmol/l
0.19
33
237
156
1469
1.75
1.19
13.9
9.2
25.62
25.07
u/l
0.22
156
1426
5
20
2.54
1.16
1.2
1.6
—
—
—
0
0
5
20
2.54
1.16
1.2
1.6
—
—
—
0
0
5
20
2.54
1.16
1.0
1.5
—
—
—
0
0
84
712
1.36
1.15
4.6
3.5
0.00
0.00
estimate
-0.00
12
146
141
1301
1.49
1.15
3.9
3.8
5.67
5.73
mmol/l
0.34
133
1211
75
627
1.35
1.12
2.6
2.5
—
—
—
0
0
147
1370
1.54
1.11
20.1
12.5
3.93
3.95
mmol/l
0.38
147
1327
7
32
2.24
1.09
1.1
1.5
—
—
—
0
0
9
48
1.92
1.02
1.2
1.1
—
—
—
0
0
9
48
1.92
1.02
1.2
1.1
—
—
—
0
0
24
166
1.52
1.01
3.9
2.3
2.25
2.47
g/l
1.20
24
151
139
1295
1.40
0.91
15.4
10.4
88.30
88.41
ml/min/173m2
0.02
127
1048
6
29
2.11
0.90
2.0
1.6
—
—
—
0
0
6
29
2.11
0.90
1.0
1.1
—
—
—
0
0
14
88
1.64
0.87
4.3
3.1
1.69
1.92
mmol/l
0.12
14
63
13
80
1.68
0.87
1.5
1.7
—
—
—
0
0
13
80
1.68
0.87
1.0
1.0
—
—
—
0
0
6
31
1.97
0.85
1.2
1.5
—
—
—
0
0
6
34
1.79
0.77
1.3
1.3
—
—
—
0
0
6
34
1.79
0.77
3.0
3.3
56.83
54.94
%
—
6
34
27
203
1.39
0.77
3.5
2.5
2.40
2.43
mmol/l
0.58
22
180
24
177
1.41
0.76
4.7
1.9
—
—
—
0
0
5
24
2.12
0.75
1.2
1.5
—
—
—
0
0
138
1299
1.33
0.72
3.3
3.4
1.19
1.24
mmol/l
0.36
128
1206
42
346
1.28
0.66
1.5
1.5
—
—
—
0
0
15
104
1.49
0.65
5.4
3.9
2.23
70.72
ug/l
—
10
87
19
139
1.41
0.64
10.9
6.8
1.07
1.06
mmol/l
0.03
19
127
17
123
1.42
0.60
4.4
5.5
106.35
103.95
mmol/l
2.40
17
123
0
21
0.00
0.60
0.0
1.9
—
13.65
—
0
21
36
298
1.26
0.55
1.4
1.4
24.13
22.18
nmol/l
0.53
28
249
128
1208
1.24
0.55
4.9
4.8
37.46
38.58
mmol/mol
1.05
122
1141
161
1568
1.51
0.54
26.0
17.4
40.46
40.33
%
0.15
152
1498
16
118
1.39
0.52
3.8
3.3
—
—
—
0
0
37
311
1.24
0.50
4.2
3.6
19.70
12.15
mg/mmol
0.29
20
192
161
1573
1.44
0.45
26.7
17.5
134.32
135.08
g/l
0.30
161
1551
35
297
1.22
0.44
1.8
2.0
—
—
—
0
0
61
548
1.18
0.42
5.2
3.5
—
—
—
0
0
18
141
1.31
0.42
1.2
1.3
25.60
126.04
iu/ml
—
5
56
0
15
0.00
0.41
0.0
1.2
—
91.20
—
0
5
0
15
0.00
0.41
0.0
2.2
—
—
—
0
0
141
1359
1.22
0.39
3.8
3.8
4.68
4.75
mmol/l
0.36
136
1279
11
147
0.73
0.39
3.1
4.0
26.20
31.33
%
—
5
96
0
19
0.00
0.39
0.0
2.2
—
7.22
—
0
19
9
67
1.36
0.39
5.8
12.9
25.02
24.20
mmol/l
—
9
62
13
99
1.34
0.36
3.2
2.4
19.77
61.13
u/ml
0.96
13
93
6
41
1.48
0.36
1.2
1.1
—
0.91
—
0
7
6
45
1.35
0.34
1.0
1.4
—
8.58
—
0
12
140
1356
1.18
0.32
3.8
3.8
1.48
1.50
mmol/l
0.15
133
1270
11
141
0.76
0.31
9.6
6.3
—
—
—
0
0
7
56
1.26
0.30
3.4
8.5
0.70
0.78
%
—
7
56
7
57
1.24
0.29
3.4
7.9
1.17
1.61
%
—
7
57
31
273
1.17
0.27
1.3
1.3
9.67
25.57
iu/ml
—
10
97
8
66
1.22
0.27
4.8
3.5
0.03
0.21
e6/l
—
8
61
8
67
1.20
0.26
1.3
1.5
—
—
—
0
0
9
74
1.23
0.25
1.4
1.5
—
—
—
0
0
5
37
1.36
0.23
1.0
1.3
—
—
—
0
0
141
1376
1.14
0.23
4.3
4.1
2.72
2.85
mmol/l
0.99
136
1288
0
10
0.00
0.21
0.0
1.3
—
105.84
—
0
10
0
12
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
30
270
1.13
0.20
1.2
1.3
4.66
11.01
u/ml
0.70
11
106
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
6
49
1.23
0.20
3.5
3.1
53.15
48.39
%
—
6
49
20
175
1.16
0.19
3.3
3.9
28.94
22.71
%
—
9
81
35
380
0.90
0.18
5.7
3.8
0.00
0.00
estimate
-0.00
13
145
5
65
0.76
0.17
2.0
1.9
—
—
—
0
0
12
141
0.84
0.17
1.4
1.5
—
—
—
0
0
5
70
0.71
0.17
1.6
1.4
—
—
—
0
0
6
77
0.77
0.16
1.7
1.9
5.67
2.90
ug/l
—
6
66
15
134
1.13
0.11
2.0
2.8
0.83
0.73
ug/l
—
9
87
7
81
0.86
0.07
1.6
1.6
—
—
—
0
0
17
162
1.05
0.02
1.9
1.6
—
—
—
0
0
10
93
1.08
0.02
4.2
2.9
55.00
69.79
ml/min/173m2
—
5
39
10
95
1.06
0.00
2.2
2.6
221.28
4511.25
u/l
—
5
39
10
95
1.06
0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
21.10
—
0
6
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
54.00
—
0
6
0
8
0.00
0.00
0.0
2.4
—
—
—
0
0
5
52
0.96
-0.00
1.8
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
7
74
0.94
-0.00
1.3
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
74
0.94
-0.00
1.3
1.5
—
—
—
0
0
7
74
0.94
-0.00
1.3
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
65.86
—
0
7
0
5
0.00
-0.00
0.0
3.2
—
131.20
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
10.20
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
0.31
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
217.00
—
0
5
5
50
1.00
-0.00
2.6
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
7
74
0.94
-0.00
1.3
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
11.43
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint G6_MENINGVIR and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have G6_MENINGVIR.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: G6_MENINGVIR – Meningitis, viral
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data