No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
828 |
4. Check minimum number of eventsNone |
828 |
5. Include endpointsNone |
828 |
6. Filter based on genotype QC (FinnGen only) |
828 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Drug-induced cataract
based on the number of shared cases.
Similar with more cases:
- Other cataract
- Disorders of lens
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4232 | 2397 | 1803 |
| Only index persons | 3685 | 2140 | 1545 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.07 | 0.05 |
| Only index persons | 0.07 | 0.08 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 56.28 | 56.55 | 55.83 |
| Only index persons | 55.90 | 56.26 | 55.39 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 828 | 490 | 338 |
| Unadjusted period prevalence (%) | 0.16 | 0.17 | 0.15 |
| Median age at first event (years) | 55.09 | 54.31 | 56.21 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 742
- Matched controls
- 7420
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H26.3
ICD-10 Finland
Drug-induced cataract
+∞
323.0
741
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
23.4
297.9
604
1170
Z96.1
ICD-10 Finland
Presence of intraocular lens
15.6
196.2
365
433
H02AB04
ATC
methylprednisolone; systemic
9.0
137.6
354
685
L04AX01
ATC
azathioprine; systemic
18.7
134.0
216
159
127
Kela drug reimbursment
Transplant complication
44.4
132.6
164
47
L04AA06
ATC
mycophenolic acid; systemic
36.0
118.0
153
53
L04AA01
ATC
[U] ciclosporin; systemic
42.0
116.7
146
43
L04AD01
ATC
ciclosporin; systemic
39.1
112.5
143
45
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
5.9
108.4
456
1587
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
8.6
108.1
268
456
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.5
102.0
459
1685
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
17.3
92.8
152
109
H20.1
ICD-10 Finland
Chronic iridocyclitis
60.0
92.6
108
21
Z94.0
ICD-10 Finland
Kidney transplant status
40.6
88.2
111
32
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
9.8
87.9
193
257
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.7
83.4
507
2345
H26.4
ICD-10 Finland
After-cataract
8.4
81.1
196
303
C03CA01
ATC
furosemide; systemic
4.7
75.8
343
1150
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
21.9
74.6
111
59
H02AB06
ATC
prednisolone; systemic
4.2
73.2
513
2567
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
6.8
70.9
201
386
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
12.2
70.1
133
130
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
21.6
69.0
103
55
M05BA04
ATC
alendronic acid; oral
7.7
66.3
167
268
H26.2
ICD-10 Finland
Complicated cataract
28.7
65.2
89
35
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
8.8
64.9
149
206
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.3
63.0
222
550
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
35.1
58.7
76
24
CJB10
NOMESCO Finland
Laser discission of secondary cataract
7.0
58.0
156
272
A12AA04
ATC
calcium carbonate; oral
25.1
57.2
81
36
H26.02
ICD-10 Finland
Presenil cataract
12.4
54.8
102
94
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
26.3
54.5
76
32
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
6.8
53.3
146
259
A11CC03
ATC
alfacalcidol; systemic
15.5
51.8
87
63
TK800
NOMESCO Finland
Hemodialysis
14.9
49.8
85
64
P01BA02
ATC
hydroxychloroquine; oral
5.6
47.7
154
334
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
3.1
47.5
408
2075
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
31.5
46.1
61
21
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
7.8
45.8
111
163
137
Kela drug reimbursment
Uraemia requiring dialysis
21.2
44.4
66
34
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.6
42.8
165
430
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
6.0
42.8
127
246
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
6.0
42.3
125
241
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.7
42.0
218
744
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
6.6
41.8
115
202
H02AB07
ATC
prednisone; oral
3.9
41.7
199
633
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.4
41.7
249
951
H02AB09
ATC
hydrocortisone; systemic
11.2
41.3
80
79
B03XA02
ATC
darbepoetin alfa; parenteral
15.1
41.0
69
50
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.1
41.0
119
224
Z49.1
ICD-10 Finland
Extracorporeal dialysis
19.0
40.9
63
36
B03XA01
ATC
erythropoietin; parenteral
37.2
40.9
52
15
J01MA12
ATC
levofloxacin; systemic
3.5
40.8
229
831
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.7
40.8
155
397
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
21.7
40.8
60
30
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.6
37.8
145
373
J01FF01
ATC
clindamycin; systemic
3.0
37.6
296
1354
R50.9
ICD-10 Finland
Fever, unspecified
3.8
37.5
183
588
S01ED51
ATC
timolol, combinations; ophthalmic
5.6
37.1
116
238
N18.0
ICD-10 Finland
End-stage renal disease
22.7
36.7
53
25
ZX120
NOMESCO Finland
Intravenous
4.6
35.9
138
354
B05DA
ATC
Isotonic solutions
22.3
35.8
52
25
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
35.6
238
967
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
24.3
35.3
50
22
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
35.2
297
1409
V03AE01
ATC
polystyrene sulfonate; oral
19.6
34.9
53
29
A07AA02
ATC
nystatin; oral
5.9
34.7
103
198
ZXA00
NOMESCO Finland
Right side
2.9
34.6
279
1283
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
7.8
34.1
81
114
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
24.3
34.0
48
21
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
29.8
33.7
45
16
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.7
32.9
79
113
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
10.7
32.5
64
65
S01BC05
ATC
ketorolac; ophthalmic
8.1
32.3
75
102
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.3
31.7
183
662
N18.8
ICD-10 Finland
Other chronic renal failure
10.3
31.5
63
66
A07EC01
ATC
sulfasalazine; oral, rectal
4.3
30.5
124
333
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
8.3
30.2
69
91
A02BC02
ATC
pantoprazole; systemic
2.6
29.5
545
3856
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.6
29.5
90
178
ZXD05
NOMESCO Finland
Urgent procedure
2.6
29.0
288
1463
XCK10
NOMESCO Finland
Photography of fundus of eye
3.9
29.0
129
376
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
18.9
28.2
43
24
H25.1
ICD-10 Finland
Senile nuclear cataract
2.8
27.8
216
945
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
8.0
27.5
64
87
H25.8
ICD-10 Finland
Other senile cataract
4.0
27.5
120
343
M04AA01
ATC
allopurinol; systemic
3.5
27.1
143
478
L88
ICPC
Rheumatoid/seropositive arthritis
6.3
26.9
74
128
Z2446
NOMESCO Finland
Social worker
4.5
26.9
101
250
Z49.2
ICD-10 Finland
Other dialysis
18.8
26.9
41
23
H30.2
ICD-10 Finland
Posterior cyclitis
145.3
26.8
28
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.6
26.7
135
436
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
11.3
26.4
50
47
J01MA02
ATC
ciprofloxacin; systemic
2.3
26.2
350
2047
ZXA05
NOMESCO Finland
Left side
2.6
26.2
249
1218
B07.9
ICD-10 Finland
Verruca simplex
7.1
25.9
65
99
N02AX02
ATC
tramadol; systemic, rectal
2.3
25.9
377
2293
L04AB04
ATC
adalimumab; parenteral
11.1
25.7
49
47
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.3
25.4
62
91
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.7
25.2
118
357
R03AC12
ATC
salmeterol; inhalant
6.2
25.1
70
123
L04AA13
ATC
leflunomide; oral
7.0
24.9
63
97
Z49.0
ICD-10 Finland
Preparatory care for dialysis
16.2
24.9
40
26
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
134.5
24.8
26
*
B05DB
ATC
Hypertonic solutions
17.1
24.7
39
24
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
6.4
24.7
67
114
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.5
24.7
126
409
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.7
24.4
115
350
L01AA01
ATC
cyclophosphamide; systemic
39.0
24.1
30
8
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.9
23.9
167
676
E0000UV
ATC
NA
2.3
23.8
343
2051
S01EC01
ATC
acetazolamide; systemic
8.9
23.7
51
61
S01ED01
ATC
timolol; ophthalmic
6.7
23.4
61
98
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.3
23.3
74
153
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.8
23.2
104
302
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
7.2
22.8
56
83
A41.9
ICD-10 Finland
Sepsis, unspecified
7.0
22.4
56
85
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.2
22.2
128
452
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
36.3
22.2
28
8
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.5
21.9
204
969
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
21.8
149
590
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
21.8
165
698
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
21.8
183
823
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
15.9
21.7
35
23
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.7
21.6
100
298
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.5
21.6
107
338
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
21.5
351
2186
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
18.1
21.5
33
19
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.6
21.4
190
880
TPX10
NOMESCO Finland
Implantation of vascular injection port
6.8
21.1
54
85
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.1
21.0
86
230
V03AE02
ATC
sevelamer; oral
25.1
21.0
29
12
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.0
20.8
134
510
H04.10
ICD-10 Finland
Dry eye syndrome
3.3
20.8
112
376
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
6.4
20.7
55
91
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
5.2
20.5
65
134
ZXA10
NOMESCO Finland
Bilateral
2.5
20.2
181
841
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.7
20.1
92
271
J01MA14
ATC
moxifloxacin; systemic
3.3
20.1
110
371
S01BC03
ATC
diclofenac; ophthalmic
8.4
20.0
44
55
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
5.9
19.9
57
104
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
75.6
19.8
22
*
7151
FHL
Kidney transplantation
107.9
19.7
21
*
Z94.4
ICD-10 Finland
Liver transplant status
41.3
19.6
24
6
A05AA02
ATC
ursodeoxycholic acid; oral
10.5
19.6
38
38
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
7.3
19.5
47
68
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.4
19.4
100
324
UJF32
NOMESCO Finland
Coloscopy
2.3
19.4
234
1256
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.3
19.4
103
342
WX002
NOMESCO Finland
Sedation and analgesia
2.4
19.3
199
988
TK810
NOMESCO Finland
Hemofiltration
23.3
19.2
27
12
J05AB11
ATC
valaciclovir; oral
2.8
19.1
135
543
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.2
19.1
52
89
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
19.0
245
1355
NF1AA
NOMESCO Finland
Hip X-ray examination
3.3
18.9
102
342
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.7
18.9
66
151
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
7.6
18.8
44
61
R03DA04
ATC
theophylline; systemic, rectal
4.9
18.5
62
136
A46
ICD-10 Finland
Erysipelas
2.7
18.5
143
607
UKC02
NOMESCO Finland
Cystoscopy
2.6
18.4
148
642
C08CA01
ATC
amlodipine; oral
2.1
18.2
287
1724
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.5
18.2
66
157
TGC00
NOMESCO Finland
Bronchial lavation
6.4
18.2
48
79
S97
ICPC
Chronic ulcer skin
4.4
18.2
68
167
S01FA04
ATC
cyclopentolate; ophthalmic
15.8
18.1
29
19
M81.9
ICD-10 Finland
Osteoporosis, unspecified
5.6
18.0
53
100
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
8.2
18.0
40
51
M01CB01
ATC
sodium aurothiomalate; parenteral
8.2
18.0
40
51
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
23.5
17.8
25
11
WX140
NOMESCO Finland
Parabulbar anesthesy
4.8
17.8
61
137
R06.0
ICD-10 Finland
Dyspnoea
2.2
17.8
218
1171
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.7
17.8
81
238
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
11.1
17.6
33
31
C07AB02
ATC
metoprolol; systemic
2.4
17.6
174
842
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
19.2
17.4
26
14
XCK00
NOMESCO Finland
Perimetry
3.7
17.3
78
227
WW200
NOMESCO Finland
Immunization
6.7
17.3
44
69
XG410
NOMESCO Finland
Flow-volume spirometry
4.5
17.3
63
151
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
15.3
17.3
28
19
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
6.0
17.2
48
85
H05BX01
ATC
cinacalcet; oral
19.8
17.0
25
13
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.7
16.9
128
535
GD1AD
NOMESCO Finland
Thorax CT examination
4.3
16.8
63
155
J45.0
ICD-10 Finland
Predominantly allergic asthma
3.2
16.8
94
323
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.6
16.8
136
591
318
Kela drug reimbursment
Teriparatide
18.4
16.6
25
14
N02AA05
ATC
oxycodone; systemic
2.6
16.5
134
580
196
Kela drug reimbursment
Paricalcitol and cinacalcet
14.7
16.4
27
19
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
16.4
91
310
C08CA05
ATC
nifedipine; systemic
3.7
16.3
73
211
KA1AE
NOMESCO Finland
Kidney ultrasound examination
6.2
16.3
44
75
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.7
16.2
41
64
H05AA02
ATC
teriparatide; parenteral
19.0
16.1
24
13
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
14.0
16.1
27
20
205
Kela drug reimbursment
Chronic hypertension
2.1
16.0
224
1265
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
6.4
16.0
42
69
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
7.6
15.9
37
51
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
16.1
15.8
25
16
M05BA01
ATC
etidronic acid; systemic
34.2
15.8
20
6
R03BB04
ATC
tiotropium bromide; inhalant
2.9
15.6
98
364
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
5.3
15.6
48
96
C08CA02
ATC
felodipine; oral
3.0
15.6
97
358
M05BX04
ATC
denosumab; parenteral
4.0
15.6
63
167
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
15.5
86
291
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.1
15.4
49
102
ZX112
NOMESCO Finland
Subcutaneous
7.2
15.3
37
54
TK820
NOMESCO Finland
Peritoneal dialysis
16.5
15.3
24
15
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.3
15.3
81
268
M81.4
ICD-10 Finland
Drug-induced osteoporosis
29.3
15.2
20
7
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
24.0
15.2
21
9
J05AB01
ATC
aciclovir; systemic
2.2
15.2
177
920
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
15.2
132
595
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
4.2
15.2
58
146
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
4.2
14.9
58
148
K06.18
ICD-10 Finland
Another gingival hyperplasia
25.6
14.7
20
8
WW500
NOMESCO Finland
Blood transfusion
4.6
14.6
51
117
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
14.6
194
1066
JJC00
NOMESCO Finland
Allogenic transplantation of liver
81.8
14.6
16
*
J01DB01
ATC
cefalexin; oral
2.1
14.6
620
5226
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
8.1
14.5
32
41
SPAT1263
SPAT
Sampling
1.9
14.4
334
2264
M05BB03
ATC
alendronic acid and colecalciferol; oral
6.3
14.4
38
63
CS494
NOMESCO Finland
Other visual field testing
5.9
14.4
40
71
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
11.7
14.4
26
23
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
27.8
14.3
19
7
ZX108
NOMESCO Finland
Inhalation
13.7
14.3
24
18
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
7.2
14.3
34
49
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
6.2
13.9
37
62
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.4
13.9
69
217
R03AC13
ATC
formoterol; inhalant
3.7
13.9
62
179
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.3
13.8
72
235
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
13.8
399
2901
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
9.3
13.8
28
31
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
10.0
13.8
27
28
XF400
NOMESCO Finland
ECG with 12 standard connections
2.3
13.8
146
724
114
Kela drug reimbursment
Glaucoma
3.0
13.7
80
283
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.2
13.7
76
258
A12BA01
ATC
potassium chloride; oral
4.4
13.6
50
121
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
76.6
13.6
15
*
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
13.6
324
2203
E000001
ATC
NA
2.1
13.5
174
942
J46
ICD-10 Finland
Status asthmaticus
5.6
13.5
39
73
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.9
13.5
37
65
M05BA07
ATC
risedronic acid; oral
4.6
13.4
46
104
SPAT1229
SPAT
Assessment of need for aid
3.0
13.4
80
285
A02BC01
ATC
omeprazole; systemic
2.0
13.4
220
1312
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
7.5
13.4
31
43
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
8.8
13.3
28
33
Z94.2
ICD-10 Finland
Lung transplant status
40.9
13.2
16
*
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
15.4
13.2
21
14
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.7
13.1
94
377
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
17.1
13.0
20
12
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
28.9
13.0
17
6
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
28.9
13.0
17
6
B01AA03
ATC
warfarin; systemic
2.2
13.0
143
719
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
19.5
13.0
19
10
J45.8
ICD-10 Finland
Mixed asthma
5.3
12.9
39
77
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
14.4
12.8
21
15
J01FA06
ATC
roxithromycin; oral
1.8
12.8
320
2202
J01DA01
ATC
[U] cefalexin; systemic
1.8
12.7
471
3665
J01EA01
ATC
trimethoprim; systemic
2.0
12.7
192
1102
P01AB01
ATC
metronidazole; oral, rectal
1.8
12.7
304
2060
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
12.6
153
804
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
12.6
272
1778
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
12.6
137
686
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
12.6
81
305
H02AB08
ATC
triamcinolone; systemic
17.7
12.6
19
11
L04AA17
ATC
[U] adalimumab; parenteral
17.7
12.6
19
11
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
9.5
12.6
25
27
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
24.8
12.5
17
7
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
5.1
12.5
39
80
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
7.1
12.5
30
44
C09AA02
ATC
enalapril; systemic
2.1
12.5
157
835
H40.6
ICD-10 Finland
Glaucoma secondary to drugs
132.2
12.5
13
*
N03AX16
ATC
pregabalin; oral
2.0
12.4
192
1111
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.9
12.4
40
85
C02CA01
ATC
prazosin; oral
8.2
12.4
27
34
ZZA00
NOMESCO Finland
Split skin graft
5.0
12.4
39
81
U14
ICPC
Kidney symptom/complaint
7.6
12.3
28
38
SPAT1254
SPAT
Administration of medicine
2.3
12.3
121
576
WX199
NOMESCO Finland
Other local analgesia
5.4
12.3
36
69
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.2
12.2
64
210
L01BB01
ATC
NA
38.2
12.2
15
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
38.2
12.2
15
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.3
12.2
61
194
C07AB07
ATC
bisoprolol; oral
1.8
12.0
342
2433
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.9
12.0
49
132
R60.0
ICD-10 Finland
Localized oedema
2.5
12.0
100
439
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.9
12.0
73
266
J01CF02
ATC
cloxacillin; systemic
6.0
11.9
32
55
S01EC04
ATC
brinzolamide; ophthalmic
4.3
11.9
44
108
K65.0
ICD-10 Finland
Acute peritonitis
8.6
11.9
25
30
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
5.2
11.8
36
72
B99
ICD-10 Finland
Other and unspecified infectious diseases
6.8
11.8
29
44
S01EA03
ATC
apraclonidine; ophthalmic
10.8
11.8
22
21
C08CA03
ATC
isradipine; systemic
9.1
11.8
24
27
B02.9
ICD-10 Finland
Zoster without complication
3.3
11.8
60
193
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.8
11.7
262
1723
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.5
11.7
54
161
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
16.7
11.7
18
11
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
16.7
11.7
18
11
A02BA02
ATC
ranitidine; systemic
2.0
11.7
161
888
R03BA02
ATC
budesonide; inhalant
2.1
11.7
150
804
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
30.6
11.7
15
5
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
19.3
11.6
17
9
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.3
11.6
110
514
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.3
11.6
42
101
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
23.3
11.6
16
7
J02AC01
ATC
fluconazole; systemic
1.8
11.6
295
2021
XCH00
NOMESCO Finland
Eye pressure measurement
4.0
11.6
46
121
S18
ICPC
Laceration/cut
1.7
11.5
325
2297
AA1AD
NOMESCO Finland
CT of head and brain
1.9
11.4
183
1071
RS220
NOMESCO Finland
NA
7.1
11.4
27
39
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
12.1
11.4
20
17
TNG10
NOMESCO Finland
Puncture of knee
8.5
11.4
24
29
H43.1
ICD-10 Finland
Vitreous haemorrhage
5.3
11.3
34
67
R11
ICD-10 Finland
Nausea and vomiting
2.8
11.3
74
282
C07AG02
ATC
carvedilol; oral
3.2
11.3
61
205
I50.9
ICD-10 Finland
Heart failure, unspecified
2.5
11.3
93
406
C03DA01
ATC
spironolactone; oral
2.5
11.2
95
419
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
25.5
11.2
15
6
L04AA11
ATC
[U] etanercept; parenteral
20.4
11.2
16
8
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.5
11.1
32
60
J01CA04
ATC
amoxicillin; systemic
1.9
11.1
599
5121
D86.0
ICD-10 Finland
Sarcoidosis of lung
7.2
11.1
26
37
TQW99
NOMESCO Finland
Other minor procedure on skin
3.5
11.1
51
152
A07EA06
ATC
budesonide; oral, local oral
4.1
11.1
42
106
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
11.1
111
533
WZA10
NOMESCO Finland
Long statement of health and health related matters
7.6
11.0
25
34
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
11.0
143
770
H40.0
ICD-10 Finland
Glaucoma suspect
2.8
11.0
73
282
602
Kela drug reimbursment
Children's severe malnutrition
44.0
10.9
13
*
R03AC02
ATC
salbutamol; inhalant
1.7
10.9
390
2937
M45
ICD-10 Finland
Ankylosing spondylitis
5.5
10.8
31
58
J45.1
ICD-10 Finland
Nonallergic asthma
2.8
10.8
71
271
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
10.8
10.8
20
19
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
10.8
218
1378
N03AX12
ATC
gabapentin; oral
2.1
10.8
129
671
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
2.2
10.8
120
602
EBA15
NOMESCO Finland
Extraction of large number of teeth
4.1
10.8
41
104
L04AA05
ATC
[U] tacrolimus; systemic
28.5
10.8
14
5
A02BC05
ATC
esomeprazole; systemic
1.7
10.7
309
2182
EBA10
NOMESCO Finland
Surgical removal of tooth
2.4
10.7
95
430
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
21.8
10.7
15
7
XW000
NOMESCO Finland
Bone marrow biopsy
3.8
10.7
45
125
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
60.9
10.6
12
*
GDG10
NOMESCO Finland
Bilateral transplantation of lung
60.9
10.6
12
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
10.6
224
1437
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.3
10.6
52
164
TQW11
NOMESCO Finland
Vacuum treatment of wound
6.0
10.5
28
48
B01AB05
ATC
enoxaparin; parenteral
1.8
10.5
231
1499
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.1
10.5
59
203
SPAT1262
SPAT
Handing over of treatment supplies
2.0
10.4
152
855
JJ5AT
NOMESCO Finland
NA
111.5
10.4
11
*
M13.9
ICD-10 Finland
Arthritis, unspecified
2.8
10.4
69
265
Z3226
NOMESCO Finland
Physiotherapist
2.0
10.4
155
880
NH3EA
NOMESCO Finland
Feet X-ray examination with load
5.7
10.4
29
53
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
33.0
10.4
13
*
6BA02
NOMESCO Finland
NA
33.0
10.4
13
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.2
10.3
107
522
K83.0
ICD-10 Finland
Cholangitis
9.0
10.3
21
24
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.5
10.3
81
343
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
10.8
10.3
19
18
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
5.0
10.3
32
66
C08CA13
ATC
lercanidipine; oral
2.2
10.3
111
552
XG466
NOMESCO Finland
Sleep oxymetry
3.8
10.3
42
114
C02EA02
ATC
NA
4.1
10.3
39
99
R03BB01
ATC
ipratropium bromide; inhalant
4.1
10.3
39
99
A07AA09
ATC
vancomycin; oral
7.6
10.2
23
31
SPAT1325
SPAT
Vaccination
1.7
10.2
253
1701
JN4BD
NOMESCO Finland
Extensive body CT
2.3
10.2
98
460
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.1
10.2
55
186
A06AD11
ATC
lactulose; oral
2.2
10.2
107
523
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
10.1
277
1920
R31
ICD-10 Finland
Unspecified haematuria
2.6
10.1
77
322
RD210
NOMESCO Finland
NA
5.4
10.1
29
55
N19
ICD-10 Finland
Unspecified kidney failure
4.1
10.1
38
96
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.9
10.0
27
47
R03DC03
ATC
montelukast; oral
2.0
10.0
140
773
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
10.0
117
601
R4110
NOMESCO Finland
Physiotherapy
1.8
10.0
210
1341
5AB14
NOMESCO Finland
NA
40.6
10.0
12
*
C02AC05
ATC
moxonidine; oral
3.5
10.0
46
138
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4.0
9.9
39
102
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
17.0
9.9
15
9
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
9.7
9.8
19
20
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.6
9.8
73
302
R03AC03
ATC
terbutaline; inhalant
2.1
9.8
117
606
UJF30
NOMESCO Finland
Ileoscopy through colon
2.3
9.7
91
424
SPAT1211
SPAT
Application of soft bandage
2.5
9.7
77
328
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
6.9
9.7
23
34
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
55.7
9.7
11
*
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
55.7
9.7
11
*
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
3.2
9.7
50
164
R03BA08
ATC
ciclesonide; inhalant
2.5
9.7
77
329
H33.0
ICD-10 Finland
Retinal detachment with retinal break
4.3
9.6
34
81
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.7
9.6
41
116
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.9
9.6
59
216
H15.1
ICD-10 Finland
Episcleritis
7.3
9.6
22
31
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
10.2
9.6
18
18
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.0
9.5
37
96
V03AE03
ATC
lanthanum carbonate; oral
15.3
9.5
15
10
WX202
NOMESCO Finland
Supraclavicular plexus blockade
6.7
9.5
23
35
A02BC03
ATC
lansoprazole; oral
1.7
9.4
218
1430
73410
ICD-8 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
101.3
9.4
10
*
5602
FHL
Internal fistula (eg Cimino)
101.3
9.4
10
*
NDB60
NOMESCO Finland
Prosthetic replacement of MCP joint of finger
101.3
9.4
10
*
M33.2
ICD-10 Finland
Polymyositis
101.3
9.4
10
*
Z94.1
ICD-10 Finland
Heart transplant status
17.8
9.4
14
8
Z3231
NOMESCO Finland
Registered nurse
1.8
9.4
205
1322
NDG30
NOMESCO Finland
Fusion of wrist, total
12.5
9.4
16
13
R4180
NOMESCO Finland
Podiatric therapy
8.2
9.4
20
25
M10.9
ICD-10 Finland
Gout, unspecified
2.8
9.4
60
227
M31.3
ICD-10 Finland
Wegener granulomatosis
22.0
9.4
13
6
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.0
9.3
54
191
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.5
9.3
42
124
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
3.1
9.3
49
163
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.0
9.2
36
94
L28
ICPC
Limited function/disability (L)
2.1
9.2
117
619
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
6.8
9.2
22
33
NHQ40
NOMESCO Finland
Amputation of toe
6.4
9.1
23
37
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
9.1
165
998
S01EE03
ATC
bimatoprost; ophthalmic
4.8
9.1
29
62
L04AB01
ATC
etanercept; parenteral
6.0
9.1
24
41
XPX08
NOMESCO Finland
Intraoperative flow measurement
11.7
9.1
16
14
N05CF01
ATC
zopiclone; oral
1.7
9.1
223
1485
X58
ICD-10 Finland
Exposure to other specified factors
2.1
9.1
110
571
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
15.8
9.1
14
9
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
37.2
9.0
11
*
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
37.2
9.0
11
*
Z99.2
ICD-10 Finland
Dependence on renal dialysis
37.2
9.0
11
*
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
37.2
9.0
11
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.3
9.0
88
416
R03DC01
ATC
zafirlukast; oral
5.4
9.0
26
50
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
8.9
165
1005
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
24.3
8.9
12
5
NK6PA
NOMESCO Finland
Measurement of bone density from one location with X-ray
24.3
8.9
12
5
N06AA09
ATC
amitriptyline; systemic
2.2
8.9
90
432
ZXE00
NOMESCO Finland
One hour or less
1.6
8.9
291
2099
WZC30
NOMESCO Finland
Teaching
2.0
8.9
115
615
S01EE01
ATC
latanoprost; ophthalmic
2.9
8.9
53
192
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
12.7
8.9
15
12
CKC12
NOMESCO Finland
Photocoagulation of retina
3.2
8.8
46
152
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
5.2
8.8
26
51
I15.0
ICD-10 Finland
Renovascular hypertension
10.9
8.8
16
15
A02BA03
ATC
famotidine; systemic
3.6
8.8
39
114
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
4.3
8.8
31
74
J96.1
ICD-10 Finland
Chronic respiratory failure
5.0
8.8
27
56
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.2
8.8
87
416
L95
ICPC
Osteoporosis
4.1
8.7
33
84
R03AK07
ATC
formoterol and budesonide; inhalant
1.8
8.7
155
931
PBM09
NOMESCO Finland
Closure of arteriovenous fistula of brachial artery
50.6
8.7
10
*
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
7.8
8.7
19
25
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
7.8
8.7
19
25
NG4AA
NOMESCO Finland
Lower leg X-ray examination
4.0
8.6
33
85
XF600
NOMESCO Finland
Bloodpressure measurement
2.7
8.6
59
233
Z3229
NOMESCO Finland
Other healthcare associate professional
2.4
8.6
76
343
M81.8
ICD-10 Finland
Other osteoporosis
11.7
8.6
15
13
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
16.5
8.6
13
8
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
16.5
8.6
13
8
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
9.1
8.6
17
19
S01FA02
ATC
scopolamine; ophthalmic
9.1
8.6
17
19
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.3
8.5
78
357
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
27.9
8.5
11
*
RS221
NOMESCO Finland
NA
5.8
8.5
23
41
J01MA01
ATC
ofloxacin; systemic
2.5
8.5
67
285
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
7.5
8.5
19
26
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.6
8.5
60
239
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
3.7
8.4
35
97
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
4.0
8.4
32
82
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
4.6
8.4
28
63
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
91.1
8.4
9
*
6112
FHL
Installation of a peritoneal dialysis or lavage catheter in an operating room
91.1
8.4
9
*
KAC00
NOMESCO Finland
Nephrectomy
12.9
8.4
14
11
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.8
8.4
53
199
JN4AD
NOMESCO Finland
Body CT examination
2.4
8.3
69
301
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
+∞
8.3
8
*
187
Kela drug reimbursment
MPA
+∞
8.3
8
*
PC6DE
NOMESCO Finland
NA
+∞
8.3
8
*
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
3.2
8.3
42
136
SPAT1216
SPAT
Assessment of functional ability
2.0
8.3
111
602
A07EC02
ATC
mesalazine; oral, rectal
2.7
8.3
54
207
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
8.3
134
779
R01AD08
ATC
fluticasone; nasal
1.7
8.3
212
1424
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.5
8.3
66
283
H26.9
ICD-10 Finland
Cataract, unspecified
5.2
8.2
24
47
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
14.7
8.2
13
9
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.8
8.2
52
196
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
4.3
8.2
29
70
D06BB04
ATC
podophyllotoxin; topical
3.1
8.2
43
144
SAA04
NOMESCO Finland
Special inverstigation of mouth
2.8
8.2
51
189
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.9
8.1
48
173
M05BA06
ATC
ibandronic acid; systemic
4.9
8.1
25
52
L73.8
ICD-10 Finland
Other specified follicular disorders
8.3
8.1
17
21
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
33.7
8.1
10
*
NDG74
NOMESCO Finland
Fusion of first IP joint
17.4
8.1
12
7
ZXX03
NOMESCO Finland
Extent of procedure, 3 units
9.1
8.1
16
18
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
8.0
140
836
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
8.0
77
362
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
7.4
8.0
18
25
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.7
7.9
51
194
JAF10
NOMESCO Finland
Repair of umbilical hernia
4.6
7.9
26
58
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.5
7.9
60
249
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
13.2
7.9
13
10
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
13.2
7.9
13
10
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.2
7.9
39
125
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
5.5
7.9
22
41
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.2
7.9
40
131
H11.3
ICD-10 Finland
Conjunctival haemorrhage
3.1
7.8
41
137
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.5
7.8
60
252
A28
ICPC
Limited function/disability NOS
2.0
7.8
101
538
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.9
7.8
46
166
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
7.1
7.8
18
26
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
9.5
7.8
15
16
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.6
7.8
33
94
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.2
7.8
28
69
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
6.5
7.7
19
30
58209
ICD-8 Finland
Chronic nephritis, Unspecified
45.5
7.7
9
*
H40.8
ICD-10 Finland
Other glaucoma
45.5
7.7
9
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
7.7
296
2202
WX882
NOMESCO Finland
High dependency care
3.6
7.7
33
95
N02AC04
ATC
dextropropoxyphene; oral
3.4
7.6
35
106
H16.9
ICD-10 Finland
Keratitis, unspecified
5.0
7.6
23
47
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
7.6
163
1034
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
7.6
48
179
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
18.6
7.6
11
6
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
7.6
277
2031
TQW40
NOMESCO Finland
Remowal of suture of skin
2.4
7.6
65
290
N30.9
ICD-10 Finland
Cystitis, unspecified
3.0
7.6
43
149
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.8
7.6
48
180
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
7.6
88
451
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
7.6
61
262
L04AB06
ATC
golimumab; parenteral
9.0
7.6
15
17
132
Kela drug reimbursment
Sarcoidosis
9.0
7.6
15
17
A04AA01
ATC
ondansetron; systemic, rectal
2.4
7.5
61
263
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.7
7.5
31
86
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.9
7.5
29
76
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.8
7.5
47
174
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
80.9
7.4
8
*
M31.7
ICD-10 Finland
Microscopic polyangiitis
80.9
7.4
8
*
ZX197
NOMESCO Finland
NA
80.9
7.4
8
*
212
Kela drug reimbursment
Gout
5.4
7.4
21
40
C90.0
ICD-10 Finland
Multiple myeloma
6.1
7.4
19
32
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
7.4
88
453
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.8
7.4
45
167
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
7.4
336
2596
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.9
7.3
28
73
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.9
7.3
28
73
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
6.9
7.3
17
25
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
11.0
7.3
13
12
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.3
7.3
35
110
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
9.5
7.3
14
15
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
7.3
7
*
M33.1
ICD-10 Finland
Other dermatomyositis
+∞
7.3
7
*
KAS40
NOMESCO Finland
Excision of transplanted kidney
+∞
7.3
7
*
ZY010
NOMESCO Finland
Hospital outpatient
2.9
7.3
43
156
WX204
NOMESCO Finland
Axillary plexus blockaced
3.2
7.3
36
116
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
5.9
7.3
19
33
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
7.2
83
422
I15.9
ICD-10 Finland
Secondary hypertension, unspecified
7.4
7.2
16
22
7531A
ICD-9 Finland
Congenital anomalies of urinary system, Cystic kidney disease
30.3
7.2
9
*
NDB78
NOMESCO Finland
Prosthetic replacement of several of finger or metacarpal
30.3
7.2
9
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
30.3
7.2
9
*
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
30.3
7.2
9
*
L01AA02
ATC
chlorambucil; oral
30.3
7.2
9
*
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
5.1
7.1
21
42
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
20.2
7.1
10
5
XX4BW
NOMESCO Finland
NA
20.2
7.1
10
5
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
8.0
7.1
15
19
R06AE07
ATC
cetirizine; oral
1.5
7.1
308
2348
RJ411
NOMESCO Finland
NA
8.9
7.1
14
16
1XC02
NOMESCO Finland
NA
8.9
7.1
14
16
N06AB04
ATC
citalopram; systemic
1.7
7.1
155
989
A01AB09
ATC
miconazole; local oral
2.2
7.1
71
342
N30.0
ICD-10 Finland
Acute cystitis
1.9
7.1
101
559
H10.4
ICD-10 Finland
Chronic conjunctivitis
10.2
7.1
13
13
L03AA02
ATC
filgrastim; parenteral
3.9
7.0
27
71
SPAT1234
SPAT
Support of social functional capacity
3.0
7.0
38
131
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
7.0
205
1419
SPAT1301
SPAT
No procedures
1.6
7.0
219
1542
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
6.9
123
736
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.7
6.9
45
173
R03BA05
ATC
fluticasone; inhalant
1.8
6.9
134
824
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.0
6.9
26
67
L82
ICD-10 Finland
Seborrhoeic keratosis
1.8
6.9
118
698
SPAT1255
SPAT
Intravenous administration of medicine
2.4
6.9
55
237
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
13.9
6.9
11
8
H01AC01
ATC
somatropin; parenteral
13.9
6.9
11
8
S01AX11
ATC
[U] ofloxacin; ophthalmic
3.3
6.9
33
104
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
6.8
88
467
R4190
NOMESCO Finland
Nutritional therapy
3.0
6.8
36
122
WX892
NOMESCO Finland
Monitored bed care
2.3
6.8
62
285
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
11.1
6.8
12
11
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
11.1
6.8
12
11
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.7
6.8
169
1120
H3603, E103
ICD-10 Finland
NA
6.2
6.8
17
28
N03.1
ICD-10 Finland
Chronic nephritic syndrome, focal and segmental glomerular lesions
40.4
6.8
8
*
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
40.4
6.8
8
*
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
16.9
6.8
10
6
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
16.9
6.8
10
6
S01KA02
ATC
hypromellose; ophthalmic
4.8
6.8
21
45
L57.0
ICD-10 Finland
Actinic keratosis
2.2
6.7
69
336
K03.66
ICD-10 Finland
Tooth plaque
2.4
6.7
56
246
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
7.3
6.7
15
21
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
4.5
6.7
22
50
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
22.7
6.7
9
*
V03AG01
ATC
sodium cellulose phosphate; systemic
22.7
6.7
9
*
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
6.5
6.7
16
25
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
4.3
6.7
23
55
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
6.0
6.6
17
29
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
6.6
64
304
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.8
6.6
39
142
J01CA08
ATC
pivmecillinam; oral
1.5
6.6
264
1965
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.0
6.6
36
125
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.7
6.6
43
166
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
12.4
6.6
11
9
NDG77
NOMESCO Finland
Other excision, reconstruction or fusion of joint of first finger
12.4
6.6
11
9
5BA08
NOMESCO Finland
NA
8.8
6.6
13
15
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
10.1
6.5
12
12
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
10.1
6.5
12
12
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
10.1
6.5
12
12
321
Kela drug reimbursment
Paricalcitol and cinacalcet
10.1
6.5
12
12
SPAT1153
SPAT
Removal of sutures
1.6
6.5
234
1698
R03AK08
ATC
formoterol and beclometasone; inhalant
2.9
6.5
37
130
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
2.9
6.5
37
130
J20
ICD-10 Finland
Acute bronchitis
2.0
6.5
78
406
R51.80
ICD-10 Finland
Headache
1.8
6.5
104
602
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.2
6.5
32
104
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
4.8
6.4
20
43
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.6
6.4
45
180
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.7
6.4
26
72
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.7
6.4
26
72
NDC40
NOMESCO Finland
Secondary prosthetic replacement in of joint of finger or metacarpal
70.4
6.4
7
*
A14AB01
ATC
nandrolone; parenteral
70.4
6.4
7
*
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
7.5
6.4
14
19
M01AE01
ATC
ibuprofen; systemic, rectal
0.6
6.4
535
5958
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.4
6.4
29
88
R06.2
ICD-10 Finland
Wheezing
2.7
6.4
41
155
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
14.5
6.4
10
7
E000003
ATC
NA
2.8
6.4
38
139
D01AE16
ATC
amorolfine; topical
1.9
6.4
87
475
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
5.0
6.4
19
39
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
8.2
6.3
13
16
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.1
6.3
68
336
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
3.7
6.3
26
73
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
11.1
6.3
11
10
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
6.3
114
684
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
9.4
6.3
12
13
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.5
6.3
48
203
TFJ02
NOMESCO Finland
Muscle biopsy of heart
18.2
6.3
9
5
9531
FHL
Arthrodesis of the hand joint
18.2
6.3
9
5
5828B
ICD-9 Finland
Chronic glomerulonephritis, With other specified pathological lesion in kidney[GLOMERULONEPHRITIS CHRONICA ALIA DEF,NEFR SDR]
+∞
6.3
6
*
9968A
ICD-9 Finland
Complications peculiar to certain specified procedures, Complications of transplanted organ
+∞
6.3
6
*
M79.6
ICD-10 Finland
Pain in limb
1.5
6.2
248
1838
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
6.2
109
650
NDL52
NOMESCO Finland
Tenosynovectomy of hand
7.1
6.2
14
20
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
26.9
6.2
8
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
26.9
6.2
8
*
H25.0
ICD-10 Finland
Senile incipient cataract
2.4
6.2
50
216
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
3.0
6.2
33
113
J01FA10
ATC
azithromycin; systemic
1.5
6.2
414
3425
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.4
6.2
51
225
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
4.5
6.2
20
45
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
6.2
69
346
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
5.8
6.2
16
28
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.3
6.2
21
50
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.3
6.2
55
251
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
7.8
6.1
13
17
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
7.8
6.1
13
17
K50.8
ICD-10 Finland
Other Crohn disease
4.7
6.1
19
41
K51.5
ICD-10 Finland
Left sided colitis
3.3
6.1
28
86
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.0
6.1
73
378
TKC20
NOMESCO Finland
Catheterisation of bladder
2.3
6.1
55
252
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.9
6.1
35
124
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.1
6.1
31
103
RJ420
NOMESCO Finland
NA
12.6
6.1
10
8
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.6
6.1
43
174
D07AB08
ATC
desonide; topical
2.0
6.1
77
410
FM1LE
NOMESCO Finland
Combined ultrasound and EKG examination of heart with tolerance test
8.7
6.1
12
14
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
6.1
181
1254
D11AH01
ATC
tacrolimus; topical
6.8
6.1
14
21
7140B
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SERONEGATIVA]
10.1
6.0
11
11
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
10.1
6.0
11
11
P01BA01
ATC
chloroquine; systemic
10.1
6.0
11
11
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
5.2
6.0
17
33
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
6.1
6.0
15
25
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
6.0
164
1111
CKD40
NOMESCO Finland
Endophotocoagulation of retina
4.6
6.0
19
42
Mortality – FinRegistry
↥Association
Association between endpoint DRUGADVERS_CATAR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DRUGADVERS_CATAR | 3.266 [2.86, 3.73] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.061 |
During the follow-up period (1.1.1998 — 31.12.2019), 634 out of 2151 females with DRUGADVERS_CATAR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DRUGADVERS_CATAR | 3.542 [3.09, 4.06] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 578 out of 1606 males with DRUGADVERS_CATAR died.
Mortality risk
Mortality risk for people of age
years, who have DRUGADVERS_CATAR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.22% | 0.562% |
| 5 | 2.003% | 3.4% |
| 10 | 4.599% | 9.293% |
| 15 | 8.461% | 17.053% |
| 20 | 13.692% | 27.482% |
Relationships between endpoints
↥Index endpoint: DRUGADVERS_CATAR – Drug-induced cataract
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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