male infertility: The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly males |
226837 |
2. Check conditionsNone |
226837 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1996 |
4. Check minimum number of eventsNone |
1996 |
5. Include endpointsNone |
1996 |
6. Filter based on genotype QC (FinnGen only) |
1996 |
Control definitions (FinnGen only)
- Control exclude
- N14_MALEGEN
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N40-N51
- Name in latin
- Infertilitas masculina
Male infertility
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 18987 | - | 18987 |
| Only index persons | 18715 | - | 18715 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.53 | - | 0.53 |
| Only index persons | 0.71 | - | 0.71 |
| Median age at first event (years) | |||
| Whole population | - | - | 33.28 |
| Only index persons | - | - | 33.23 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1996 | - | 1996 |
| Unadjusted period prevalence (%) | 0.88 | - | 0.88 |
| Median age at first event (years) | 33.82 | - | 33.82 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1775
- Matched controls
- 17750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N46
ICD-10 Finland
Male infertility
7393.6
323.0
1599
17
Z31.4
ICD-10 Finland
Procreative investigation and testing
9.3
192.6
438
604
60699
ICD-8 Finland
Sterility, male
+∞
109.5
104
*
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
11.9
85.1
162
149
KFB00
NOMESCO Finland
Biopsy of testis
113.3
70.4
76
7
L02BG04
ATC
letrozole; oral
47.5
60.0
73
16
G03GA01
ATC
chorionic gonadotrophin; parenteral
27.7
43.1
59
22
KGH10
NOMESCO Finland
Operation for phimosis
60.3
40.4
47
8
N47
ICD-10 Finland
Redundant prepuce, phimosis and paraphimosis
24.5
40.3
57
24
Z31.6
ICD-10 Finland
General counselling and advice on procreation
7.3
37.3
92
132
6060A
ICD-9 Finland
Infertility, male, Azoospermia
+∞
35.5
34
*
TKF00
NOMESCO Finland
Needle biopsy of testis
+∞
33.4
32
*
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
3.2
32.6
186
630
60500
ICD-8 Finland
Redundant prepuce and phimosis, Phimosis
+∞
32.4
31
*
KFB01
NOMESCO Finland
Microscope-assisted testicular biopsy for assisted reproduction treatments
+∞
31.3
30
*
W15
ICPC
Infertility/subfertility female
24.4
30.6
43
18
121
Kela drug reimbursment
Severe hypofunction of sexual glands
9.4
28.8
60
66
N40
ICD-10 Finland
Hyperplasia of prostate
3.3
25.7
134
424
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.9
25.7
476
2887
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
10.7
25.3
49
47
XKD00
NOMESCO Finland
Uroflowmetry
3.2
24.1
136
455
N43.3
ICD-10 Finland
Hydrocele, unspecified
19.1
21.3
32
17
6050A
ICD-9 Finland
Redundant prepuce and phimosis[PHIMOSIS]
+∞
20.9
20
*
N97.4
ICD-10 Finland
Female infertility associated with male factors
111.3
20.6
22
*
KFH30
NOMESCO Finland
Vasovasostomy
58.2
19.9
23
*
7501
FHL
Testicular exploration (includes removal of biopsy, detorsion or appendix test)
40.6
19.5
24
6
KFC00
NOMESCO Finland
Unilateral orchiectomy
7.4
18.5
44
61
E29.1
ICD-10 Finland
Testicular hypofunction
4.0
18.0
72
184
N43.4
ICD-10 Finland
Spermatocele
13.2
17.4
30
23
G03GA05
ATC
follitropin alfa; parenteral
171.5
16.5
17
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.8
15.9
103
380
7542
FHL
Circumcisio
60.6
15.8
18
*
KFD20
NOMESCO Finland
Excision of hydrocele of testis
+∞
15.6
15
*
N02BE01
ATC
paracetamol; systemic, rectal
1.5
15.5
1223
10479
Z31.5
ICD-10 Finland
Genetic counselling
3.1
15.1
82
270
SPAT1312
SPAT
General health counselling
1.6
14.4
387
2570
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.3
14.2
34
1039
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
14.1
456
3172
Z00.0
ICD-10 Finland
General medical examination
1.8
13.9
248
1452
Q98.0
ICD-10 Finland
Klinefelter syndrome karyotype 47,XXY
24.0
13.8
19
8
UKC02
NOMESCO Finland
Cystoscopy
2.4
13.7
121
529
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
5.6
13.6
39
71
7527
FHL
Vasoepididymostomy
+∞
13.6
13
*
6068A
ICD-9 Finland
Infertility, male, Infertility due to extratesticular causes
+∞
13.6
13
*
6069X
ICD-9 Finland
Infertility, male, Male infertility, unspecified
+∞
13.6
13
*
127
Kela drug reimbursment
Transplant complication
4.3
13.5
50
120
KED22
NOMESCO Finland
Transurethral resection of prostate
21.3
13.3
19
9
L04AA06
ATC
mycophenolic acid; systemic
4.2
13.2
50
123
SPAT1153
SPAT
Removal of sutures
1.6
12.8
335
2197
101
Kela drug reimbursment
Anterior pituitary hypofunction
5.6
12.7
36
65
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.2
12.5
125
584
E23.04
ICD-10 Finland
Hypogonadotropic hypogonadism
3.7
12.4
54
151
Q98.4
ICD-10 Finland
Klinefelter syndrome, unspecified
37.8
12.2
15
*
F29
ICD-10 Finland
Unspecified nonorganic psychosis
0.2
12.0
16
658
J01MA02
ATC
ciprofloxacin; systemic
1.5
11.9
440
3141
N50.8
ICD-10 Finland
Other specified disorders of male genital organs
11.8
11.8
21
18
6061A
ICD-9 Finland
Infertility, male, Oligospermia
+∞
11.5
11
*
L02BA01
ATC
tamoxifen; oral
11.9
11.3
20
17
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.0
11.3
44
112
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
3.3
11.2
55
170
F20.9
ICD-10 Finland
Schizophrenia, unspecified
0.0
11.1
*
307
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
0.1
11.0
*
337
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
10.9
489
3630
N44
ICD-10 Finland
Torsion of testis
28.2
10.7
14
5
N97.9
ICD-10 Finland
Female infertility, unspecified
17.9
10.7
16
9
A98
ICPC
Health maint/preventive medicine
1.9
10.5
1664
15779
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
9.2
10.5
21
23
SPAT1308
SPAT
Sexual health counselling
3.1
10.5
57
190
-
ICD-10 Finland
NA
4.2
10.5
38
91
7525
FHL
Detection of vas deferens for exploration (possibly vasotomy or vasography)
+∞
10.4
10
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
7.8
10.4
23
30
Z94.0
ICD-10 Finland
Kidney transplant status
4.5
10.1
34
76
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.4
10.1
84
360
XJH00
NOMESCO Finland
Transanal ultrasonography
4.1
10.0
38
95
9061/3-C62.9
ICD-O-3
Seminoma, NOS, of testis, NOS
9.2
10.0
20
22
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
10.0
186
1100
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
0.0
9.9
*
243
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
7.7
9.9
22
29
SPAT1195
SPAT
Antenatal classes
2.5
9.9
74
300
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
5.2
9.8
29
56
N02AX02
ATC
tramadol; systemic, rectal
1.4
9.7
512
3908
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
7.4
9.7
22
30
N05AH03
ATC
olanzapine; systemic
0.4
9.6
34
876
N05AH02
ATC
clozapine; systemic
0.1
9.6
5
369
7526
FHL
Vasovasostomy
+∞
9.4
9
*
6030A
ICD-9 Finland
Hydrocele, Encysted hydrocele
+∞
9.4
9
*
N48.1
ICD-10 Finland
Balanoposthitis
3.6
9.3
41
117
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.7
9.3
60
224
J01AA02
ATC
doxycycline; systemic
1.4
9.2
1054
9172
SPAT1197
SPAT
Extensive health check-up of expecting family
2.4
9.1
73
308
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
5.2
9.1
27
53
D19
ICPC
Teeth/gum symptom/complaint
1.5
9.1
369
2669
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
8.9
649
5234
M01AC06
ATC
meloxicam; systemic, rectal
1.5
8.9
403
2984
JN4BD
NOMESCO Finland
Extensive body CT
2.0
8.9
110
566
KFD96
NOMESCO Finland
Other excision or ligature of scrotal organs
50.2
8.7
10
*
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
6.6
8.7
21
32
7503
FHL
Hydrosel or funicular surgery
27.6
8.5
11
*
Z31.2
ICD-10 Finland
In vitrofertilization
20.1
8.5
12
6
A55
ICPC
General and Unspecified, Local injection/infiltration
4.2
8.4
30
72
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
4.2
8.4
30
72
N43.0
ICD-10 Finland
Encysted hydrocele
+∞
8.3
8
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
8.3
134
758
N18.8
ICD-10 Finland
Other chronic renal failure
3.8
8.2
33
88
M03BX02
ATC
tizanidine; oral
1.3
8.2
944
8155
A02BC02
ATC
pantoprazole; systemic
1.3
8.1
768
6436
N05AX12
ATC
aripiprazole; systemic
0.3
8.1
19
583
L04AA01
ATC
[U] ciclosporin; systemic
4.6
8.0
26
57
N48.8
ICD-10 Finland
Other specified disorders of penis
10.8
7.8
14
13
WZC30
NOMESCO Finland
Teaching
1.7
7.8
144
853
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.7
319
2308
Y10
ICPC
Infertility/subfertility male
15.1
7.7
12
8
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.1
7.7
28
69
H02AB04
ATC
methylprednisolone; systemic
1.7
7.6
146
872
SPAT1263
SPAT
Sampling
1.4
7.6
499
3935
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
4.0
7.6
28
70
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
10.1
7.5
14
14
J01EA01
ATC
trimethoprim; systemic
2.3
7.5
65
287
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
4.4
7.4
25
57
G04CA01
ATC
alfuzosin; oral
1.8
7.4
136
802
G03GA06
ATC
follitropin beta; parenteral
80.4
7.4
8
*
RD211
NOMESCO Finland
NA
2.5
7.4
55
224
N48.4
ICD-10 Finland
Impotence of organic origin
3.3
7.3
34
103
WZA90
NOMESCO Finland
Other doctors statement
1.5
7.3
315
2297
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
7.3
153
939
G03GA02
ATC
human menopausal gonadotrophin; parenteral
+∞
7.3
7
*
KED76
NOMESCO Finland
TUVP
+∞
7.3
7
*
M01AH05
ATC
etoricoxib; oral
1.3
7.1
843
7245
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
8.8
7.0
14
16
SPAT1301
SPAT
No procedures
1.4
7.0
311
2283
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.0
7.0
38
130
H02AB06
ATC
prednisolone; systemic
1.3
6.9
528
4251
Z49.0
ICD-10 Finland
Preparatory care for dialysis
5.2
6.9
20
39
XKD06
NOMESCO Finland
Physiologic investigation of micturition
4.1
6.9
25
62
P72
ICPC
Schizophrenia
0.1
6.9
*
253
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
6.8
223
1536
J02AC01
ATC
fluconazole; systemic
1.5
6.7
224
1547
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.1
6.7
74
364
KFD30
NOMESCO Finland
Operation for spermatocele
22.6
6.7
9
*
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
22.6
6.7
9
*
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
6.4
6.6
16
25
L03AA13
ATC
pegfilgrastim; parenteral
4.2
6.6
23
55
N41.1
ICD-10 Finland
Chronic prostatitis
3.1
6.6
33
107
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.8
6.6
26
70
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.5
1121
10094
JONO
NOMESCO Finland
NA
3.5
6.5
28
81
R33
ICD-10 Finland
Retention of urine
2.7
6.5
42
159
V03AE02
ATC
sevelamer; oral
5.7
6.4
17
30
75210
ICD-8 Finland
Congenital anomalies of genital organs, Undescended testicle
2.8
6.4
38
137
B03XA01
ATC
erythropoietin; parenteral
7.4
6.4
14
19
45610
ICD-8 Finland
Varicose veins of other sites, Of scrotum
7.4
6.4
14
19
G04CA02
ATC
tamsulosin; oral
1.5
6.4
190
1277
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.4
557
4564
KFA00
NOMESCO Finland
Exploration of testis
11.1
6.3
11
10
G95.8
ICD-10 Finland
Other specified diseases of spinal cord
9.3
6.3
12
13
KED52
NOMESCO Finland
Visual laser resection of prostate
+∞
6.3
6
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.6
6.2
44
174
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.8
6.2
36
128
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.5
6.2
45
184
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.4
6.2
258
1870
J01MA12
ATC
levofloxacin; systemic
1.6
6.2
177
1182
M01AX17
ATC
nimesulide; oral
1.5
6.1
208
1446
R50.9
ICD-10 Finland
Fever, unspecified
1.5
6.1
176
1179
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
2.3
6.0
52
230
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.0
6.0
74
384
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
261
257
11.53
238.21
1.6
1.6
11.5
7.7
iu/l
3.47
185
210
377
666
6.75
211.44
1.8
1.6
6.4
4.4
u/l
7.17
293
560
253
283
10.09
210.23
8.5
6.2
—
—
—
0
0
652
2780
3.00
106.03
3.2
2.2
15.0
14.8
nmol/l
0.41
609
2587
306
852
4.06
97.45
1.9
1.4
—
—
—
0
0
82
67
12.72
83.38
1.5
1.3
10.5
9.7
u/l
0.17
69
52
198
524
4.08
66.77
1.7
1.8
256.9
266.8
mu/l
0.20
193
492
299
1314
2.50
41.78
6.5
5.5
—
—
—
0
0
247
1022
2.62
39.01
2.5
1.9
216.6
220.8
pmol/l
0.22
237
980
300
1422
2.31
35.03
2.5
1.8
31.2
34.9
nmol/l
3.43
295
1400
58
133
4.46
23.46
4.9
6.3
6.3
30.0
u/l
0.99
13
21
436
2795
1.72
20.24
4.4
2.8
0.0
0.0
estimate
1.23
133
917
1419
12161
1.58
18.21
3.3
3.3
3.0
2.3
mu/l
0.23
1338
11404
624
4640
1.50
14.80
3.6
2.5
—
—
—
0
0
824
6490
1.46
14.55
3.4
2.7
1.5
1.4
ug/l
0.34
772
5947
1125
9403
1.45
14.44
2.9
2.8
15.0
14.8
pmol/l
2.33
1051
8739
729
5682
1.45
13.27
3.7
2.5
0.0
0.0
estimate
0.50
138
942
366
2492
1.57
12.78
3.5
2.7
1.0
1.0
kg/l
0.13
43
290
728
5728
1.43
12.36
3.7
2.5
0.0
0.0
estimate
0.69
131
916
648
4999
1.44
12.23
3.0
2.4
22.1
21.8
%
0.12
209
1275
721
5685
1.42
12.01
4.6
3.6
0.0
0.0
estimate
0.00
142
999
170
971
1.82
11.46
2.5
2.4
65.6
76.9
ml/min/173m2
2.07
63
326
163
923
1.83
11.30
2.2
2.1
8.0
9.8
ug/l
0.39
146
836
194
1166
1.74
10.99
2.5
2.2
350.6
360.1
nmol/l
0.35
178
1079
35
98
3.62
10.92
1.6
1.4
0.1
0.1
nmol/l
0.01
26
84
194
1201
1.68
9.86
5.5
5.0
215.2
232.3
u/l
2.60
186
1157
306
2132
1.51
9.43
4.0
2.3
1.7
2.5
e6/l
3.15
282
1905
1103
9587
1.34
9.08
3.8
3.4
7.5
7.8
mm/h
0.30
1038
9089
330
2358
1.48
8.97
3.3
3.0
1482.6
1029.5
ng/l
0.42
279
1859
19
42
4.56
8.12
1.6
1.5
—
—
—
0
0
21
51
4.15
8.00
7.2
5.1
—
—
—
0
0
750
6250
1.32
7.92
4.2
2.6
51.6
932.0
e6/l
—
9
84
473
3687
1.37
7.79
2.3
1.9
0.6
0.6
ug/l
0.29
217
1570
386
2938
1.39
7.31
4.0
2.8
0.2
0.4
e6/l
3.02
317
2188
106
607
1.79
7.15
7.3
5.6
145.9
100.6
ng/l
1.59
96
573
347
2615
1.40
6.95
1.8
2.2
—
—
—
0
0
1423
13046
1.32
6.95
3.3
3.1
—
—
—
0
0
1636
15336
1.37
6.67
13.3
10.6
23.7
23.6
mg/l
0.04
1259
11615
451
3570
1.34
6.60
2.5
2.4
2198.2
3416.5
umol/l
0.39
423
3275
589
4869
1.30
6.27
4.0
3.5
—
—
—
0
0
1128
10104
1.27
6.24
8.2
7.3
72.8
75.7
u/l
2.18
1088
9667
1898
18388
1.66
5.63
17.9
15.0
6.5
6.6
e9/l
1.34
1859
17969
316
2424
1.36
5.62
1.7
2.1
—
—
—
0
0
1709
16238
1.36
5.53
4.2
3.8
2.9
3.0
mmol/l
2.30
1628
15537
1897
18387
1.64
5.47
17.9
15.0
146.4
147.4
g/l
2.70
1882
18193
1896
18375
1.64
5.47
17.9
14.9
4.9
4.9
e12/l
2.25
1861
17955
1892
18329
1.62
5.44
17.9
14.9
243.2
244.4
e9/l
0.41
1861
17947
72
401
1.83
5.39
9.5
5.6
1450.8
792.0
iu/ml
0.42
12
55
71
394
1.83
5.38
3.9
4.4
1.1
1.4
mmol/l
3.00
71
386
896
7903
1.24
5.33
8.9
10.8
3.9
4.0
e9/l
1.22
810
6975
1789
17164
1.41
5.12
9.7
8.4
34.0
35.8
u/l
2.87
1758
16803
540
4515
1.27
5.08
2.5
2.2
72.0
69.1
nmol/l
1.76
508
4234
1692
16100
1.33
5.03
4.0
3.6
1.3
1.3
mmol/l
2.07
1626
15458
549
4607
1.26
5.00
3.1
2.5
171.9
182.0
ug/l
0.44
526
4376
354
2815
1.31
4.90
2.4
1.9
1.4
0.9
mg/l
0.71
246
1964
163
1141
1.47
4.90
16.4
9.6
9.8
8.3
mmol/l
2.08
157
1096
1697
16173
1.33
4.85
4.0
3.6
4.7
4.8
mmol/l
2.12
1627
15549
36
164
2.22
4.73
2.1
1.6
—
—
—
0
0
1566
14780
1.28
4.73
14.4
11.7
139.7
139.8
mmol/l
1.31
1533
14433
55
295
1.89
4.67
4.7
2.8
340.0
1927.0
u/ml
—
5
14
276
2133
1.34
4.66
2.4
2.1
3.1
2.8
mg/l
1.19
248
1855
239
1813
1.36
4.55
2.8
2.5
0.5
0.8
e6/l
1.75
155
982
213
1587
1.38
4.54
13.1
7.8
1.0
1.0
mmol/l
0.73
205
1511
1643
15622
1.29
4.53
3.8
3.4
1.4
1.5
mmol/l
2.42
1572
14979
545
4620
1.25
4.48
3.3
2.8
56.9
79.1
ng/l
0.19
335
2610
1574
14906
1.26
4.36
14.5
11.7
4.0
4.0
mmol/l
2.45
1538
14524
114
765
1.52
4.24
6.1
4.1
1.2
1.2
mmol/l
0.68
109
707
25
104
2.42
4.06
1.6
1.3
—
—
—
0
0
36
176
2.06
4.01
2.3
1.6
—
—
—
0
0
1496
14130
1.23
3.99
3.7
3.4
5.9
5.9
mmol/l
0.69
1421
13347
41
212
1.95
3.93
2.0
1.6
—
—
—
0
0
216
1652
1.34
3.92
4.1
2.7
15.3
14.9
umol/l
0.32
206
1573
6
5
12.03
3.76
1.2
1.0
—
—
—
0
0
62
372
1.69
3.70
1.7
1.6
106.0
102.9
u/ml
0.14
17
72
51
290
1.78
3.67
2.7
1.9
—
—
—
0
0
110
757
1.48
3.66
1.9
1.7
—
—
—
0
0
192
1461
1.35
3.61
4.3
2.8
27.1
25.8
%
0.58
175
1309
35
177
1.99
3.59
2.1
1.5
—
—
—
0
0
541
4677
1.21
3.58
9.2
7.2
1.2
1.2
mmol/l
0.22
504
4342
40
213
1.90
3.55
3.0
2.0
—
—
—
0
0
412
3466
1.24
3.55
1.5
1.5
—
—
—
0
0
32
158
2.04
3.51
2.1
1.5
—
—
—
0
0
113
790
1.46
3.49
9.0
12.2
0.8
0.7
%
2.71
113
784
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
57
341
1.69
3.46
4.1
3.5
0.3
0.3
u/ml
0.77
29
178
200
1542
1.33
3.45
4.2
2.7
2.3
2.3
g/l
0.33
189
1454
75
482
1.58
3.44
3.7
4.3
58.0
52.4
%
1.01
75
476
1523
14483
1.22
3.43
11.4
9.4
92.3
94.1
ml/min/173m2
2.44
1292
11972
17
64
2.67
3.39
2.8
1.6
—
—
—
0
0
25
115
2.19
3.29
1.4
1.6
—
—
—
0
0
89
604
1.50
3.21
1.1
1.2
148.0
138.9
iu/ml
0.07
38
213
25
117
2.15
3.16
1.4
1.6
—
—
—
0
0
716
6411
1.18
3.15
6.6
6.3
11.0
12.4
umol/l
3.64
698
6138
25
118
2.13
3.10
1.4
1.6
—
—
—
0
0
15
56
2.69
3.06
1.0
1.0
4.6
5.3
iu/ml
—
5
16
248
2004
1.27
3.03
1.6
1.6
23318804.3
29103639.7
pmol/l
0.08
223
1773
589
5206
1.19
2.99
10.9
7.6
1.2
1.2
mmol/l
0.48
498
4443
5
5
10.02
2.98
1.0
1.0
—
—
—
0
0
35
191
1.85
2.93
1.3
1.6
—
—
—
0
0
16
64
2.51
2.87
2.1
1.9
5.4
1.6
u/field
—
10
31
16
64
2.51
2.87
2.9
1.6
—
—
—
0
0
12
41
2.94
2.86
2.8
2.0
—
—
—
0
0
24
116
2.08
2.83
1.3
1.6
—
—
—
0
0
21
97
2.18
2.77
2.5
1.5
—
—
—
0
0
17
72
2.37
2.72
2.8
1.5
—
—
—
0
0
24
118
2.05
2.72
1.3
1.6
—
—
—
0
0
24
118
2.05
2.72
1.3
1.6
—
—
—
0
0
354
3012
1.21
2.71
1.3
1.3
1.5
1.9
u/ml
0.50
135
893
157
1214
1.32
2.70
4.3
3.5
28.5
27.5
%
0.70
121
917
5
168
0.30
2.69
2.0
2.3
182.6
142.8
nmol/l
—
5
136
43
257
1.69
2.68
1.0
1.2
—
42.9
—
0
7
68
456
1.51
2.65
1.3
1.2
—
—
—
0
0
47
289
1.64
2.64
2.8
1.9
—
—
—
0
0
1443
13784
1.17
2.52
5.0
4.3
38.9
38.8
mmol/mol
0.18
1377
13204
7
16
4.39
2.47
2.3
2.3
172.1
111.0
ng/l
—
7
16
47
297
1.60
2.40
4.1
3.9
3.8
4.1
e9/l
0.70
47
297
48
305
1.59
2.40
4.4
4.2
56.2
56.3
%
0.03
48
305
13
52
2.51
2.36
1.9
1.8
—
—
—
0
0
238
1976
1.23
2.32
4.4
4.0
0.8
0.8
mmol/l
0.07
230
1875
98
725
1.37
2.30
1.3
1.3
—
—
—
0
0
59
398
1.50
2.28
1.1
1.1
—
—
—
0
0
59
398
1.50
2.28
1.1
1.2
—
—
—
0
0
19
92
2.08
2.27
2.7
2.2
—
—
—
0
0
19
92
2.08
2.27
2.8
2.2
—
—
—
0
0
19
92
2.08
2.27
2.7
2.2
—
—
—
0
0
380
3309
1.18
2.25
3.7
3.3
2.3
2.4
mmol/l
0.29
354
3011
393
3432
1.18
2.25
5.1
4.3
11.5
9.2
mg/mmol
0.30
292
2424
37
224
1.66
2.25
1.1
1.1
—
—
—
0
0
325
3756
0.84
2.22
1.8
2.0
1.4
1.4
%
1.33
291
3418
75
535
1.42
2.19
1.3
1.3
240.3
186.1
miu/ml
0.55
27
224
476
5325
0.86
2.17
3.1
3.5
35.8
39.0
u/l
0.40
452
5071
412
3631
1.17
2.11
2.2
2.2
220.4
376.6
u/l
2.80
400
3447
44
284
1.56
2.09
1.2
1.3
3.6
3.6
u/ml
0.00
17
106
9
31
2.91
2.07
1.2
1.4
—
—
—
0
0
229
1922
1.22
2.03
1.3
1.2
24.2
26.1
iu/ml
0.12
65
572
287
2464
1.19
2.01
2.8
2.4
—
—
—
0
0
18
90
2.01
2.00
1.8
2.3
22.6
24.4
mg/l
—
5
23
27
155
1.75
2.00
2.8
1.7
—
—
—
0
0
115
892
1.31
2.00
1.3
1.3
424.4
324.4
u/ml
0.22
110
835
88
658
1.35
1.97
4.3
2.8
1.3
1.4
mmol/l
0.13
65
494
20
105
1.91
1.95
7.1
4.0
—
—
—
0
0
64
454
1.42
1.95
1.3
1.3
—
—
—
0
0
179
1471
1.24
1.95
1.7
1.6
1275.5
1120.7
nmol/l
1.61
140
1168
12
51
2.36
1.95
3.5
2.9
—
—
—
0
0
12
51
2.36
1.95
3.6
2.9
—
—
—
0
0
12
51
2.36
1.95
3.6
2.9
—
—
—
0
0
12
51
2.36
1.95
3.7
2.9
—
—
—
0
0
5
11
4.55
1.94
15.2
2.1
—
—
—
0
0
36
226
1.60
1.94
1.3
1.3
19.6
24.2
u/l
0.17
30
198
80
593
1.36
1.90
3.7
3.4
1.6
1.6
%
0.11
80
588
78
578
1.36
1.86
3.6
3.3
0.6
0.7
%
0.38
72
557
60
425
1.42
1.86
1.1
1.1
—
—
—
0
0
205
1720
1.21
1.84
1.3
1.2
14.2
8.2
u/ml
0.58
106
781
191
1594
1.22
1.81
3.2
3.2
2.4
2.4
mmol/l
0.11
176
1406
61
436
1.41
1.81
1.4
1.3
283.6
236.2
u/ml
0.62
43
283
7
23
3.05
1.80
15.4
5.5
5.2
6.6
mmol/l
—
7
23
62
445
1.41
1.80
3.7
2.8
190.9
177.4
%
0.45
62
428
29
176
1.66
1.79
1.4
1.4
—
0.3
nmol/l
—
0
13
49
699
0.69
1.78
2.6
2.9
—
—
—
0
0
20
109
1.84
1.77
2.9
2.1
—
—
—
0
0
64
466
1.39
1.72
1.5
1.3
62.2
160.0
pmol/l
0.65
21
117
36
235
1.54
1.68
1.4
1.4
—
—
—
0
0
160
1324
1.23
1.67
8.4
10.0
0.9
0.9
mmol/l
0.02
126
1053
40
270
1.49
1.61
3.8
2.2
16.0
18.2
%
2.18
23
120
26
161
1.62
1.52
1.6
1.5
262.2
288.5
pmol/l
0.19
18
127
5
15
3.34
1.52
1.2
1.0
—
—
—
0
0
7
27
2.60
1.51
1.0
1.0
—
—
—
0
0
38
260
1.47
1.46
1.6
1.3
—
—
—
0
0
22
132
1.67
1.46
2.8
2.0
—
—
—
0
0
5
16
3.13
1.44
1.0
1.0
—
—
—
0
0
39
270
1.45
1.42
1.2
1.3
3.7
3.8
u/ml
0.06
23
133
437
3976
1.13
1.41
4.5
2.8
62.3
57.4
u/l
0.35
415
3753
20
118
1.70
1.41
3.0
2.2
—
—
—
0
0
146
1221
1.21
1.41
1.9
1.7
—
—
—
0
0
59
441
1.35
1.40
1.7
1.8
1.3
1.5
g/l
0.88
52
381
29
190
1.53
1.37
1.1
1.1
—
—
—
0
0
6
23
2.61
1.36
1.8
2.6
—
—
—
0
0
0
37
0.00
1.34
0.0
1.2
—
—
—
0
0
771
7255
1.10
1.33
6.4
5.2
6.7
6.8
mmol/l
0.49
739
6840
9
42
2.15
1.33
4.1
3.3
—
—
—
0
0
9
42
2.15
1.33
4.1
3.3
—
—
—
0
0
9
42
2.15
1.33
4.1
3.3
—
—
—
0
0
63
816
0.76
1.31
2.5
2.8
—
—
—
0
0
139
1174
1.20
1.24
17.3
15.4
1.2
1.2
inr
0.23
16
184
140
1184
1.20
1.23
1.9
1.7
—
—
—
0
0
43
313
1.38
1.23
1.6
1.5
—
—
—
0
0
12
63
1.91
1.22
7.4
6.5
—
—
—
0
0
539
5003
1.11
1.22
7.3
5.6
37.5
37.5
g/l
0.00
519
4707
18
109
1.66
1.19
1.7
1.3
60999.0
108220.1
e6/l
0.33
13
85
1358
13167
1.10
1.18
14.1
13.3
13.4
13.3
%
0.86
1336
12899
94
768
1.24
1.17
1.0
1.1
—
—
—
0
0
30
207
1.46
1.15
2.3
1.9
1.4
1.8
mmol/l
2.32
30
201
85
1042
0.81
1.15
1.4
1.8
—
—
—
0
0
75
603
1.25
1.09
1.3
1.4
—
—
—
0
0
9
166
0.54
1.07
2.0
3.3
—
—
—
0
0
22
145
1.52
1.06
1.0
1.1
—
—
—
0
0
19
121
1.58
1.05
3.1
2.1
16.5
16.2
%
—
8
60
195
1720
1.15
1.05
3.1
2.5
0.5
0.5
e6/l
0.24
114
885
10
179
0.56
1.05
6.0
12.0
0.5
0.6
mmol/l
—
10
164
26
179
1.46
1.03
5.0
4.8
209.3
176.5
u/ml
0.06
26
167
220
1970
1.13
0.96
3.1
3.1
148.4
160.0
ug/g
0.24
187
1717
1334
12978
1.08
0.96
2.8
3.1
47.2
51.6
u/l
1.40
1279
12522
49
381
1.29
0.95
2.8
1.7
—
—
—
0
0
14
85
1.65
0.94
1.3
2.0
—
—
—
0
0
108
919
1.19
0.94
1.3
1.2
13.3
48.2
au/ml
—
5
35
17
109
1.56
0.93
1.6
2.4
33.6
33.2
pg
0.21
17
109
6
27
2.23
0.93
2.2
2.0
78.2
93.6
ug/l
—
6
27
36
270
1.34
0.91
1.9
1.7
20948.2
15759.6
e6/l
0.38
27
204
191
1703
1.13
0.90
2.2
1.7
—
—
—
0
0
414
3863
1.09
0.84
1.7
1.7
96.3
97.0
pmol/l
0.10
253
2174
85
716
1.20
0.84
1.6
2.7
67.5
67.5
g/l
0.02
78
682
6
112
0.53
0.83
2.3
2.1
—
—
—
0
0
295
2714
1.10
0.82
1.6
1.6
—
—
—
0
0
6
32
1.88
0.81
1.5
1.2
—
—
—
0
0
11
177
0.62
0.81
1.0
1.1
264.6
268.7
mg/l
0.08
11
165
15
97
1.55
0.81
1.1
1.2
1546.2
1517.5
miu/ml
0.04
15
97
38
294
1.30
0.80
1.1
1.1
114.8
113.3
%
0.10
38
273
112
975
1.16
0.77
2.3
2.3
37.4
16.0
au/ml
1.23
14
91
45
359
1.26
0.76
2.6
2.6
—
—
—
0
0
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
10
160
0.62
0.73
1.6
1.6
12.5
12.7
umol/l
—
10
155
7
38
1.84
0.73
1.1
1.3
—
—
—
0
0
21
150
1.40
0.73
3.5
2.7
558.2
681.2
e6/l
—
6
48
5
25
2.00
0.72
1.2
1.1
—
—
—
0
0
5
25
2.00
0.72
1.2
1.1
122.6
96.1
%
—
5
25
6
106
0.56
0.72
2.2
2.9
34.0
50.7
umol/l
—
6
101
7
39
1.80
0.72
1.4
2.1
—
—
—
0
0
126
1113
1.14
0.72
7.8
4.5
1.7
1.8
mmol/l
0.24
95
920
10
60
1.67
0.72
1.1
1.1
—
—
—
0
0
13
84
1.55
0.72
2.5
2.1
—
—
—
0
0
216
2360
0.90
0.71
3.4
3.3
683.3
639.5
ng/l
0.06
141
1641
19
262
0.72
0.68
4.7
2.5
21.8
27.9
mg/l
0.29
14
173
33
257
1.29
0.68
1.1
1.1
14.2
12.1
au/ml
—
5
22
7
42
1.67
0.68
1.6
1.1
—
—
—
0
0
38
302
1.26
0.68
1.1
1.1
—
—
—
0
0
18
127
1.42
0.68
1.6
1.6
67.0
56.7
%
0.50
12
88
13
191
0.68
0.66
1.4
1.9
—
—
—
0
0
5
28
1.79
0.66
2.2
1.9
—
—
—
0
0
5
28
1.79
0.66
1.0
1.0
—
—
—
0
0
18
129
1.40
0.63
3.9
3.3
7.1
8.8
mg/l
0.82
13
109
5
30
1.67
0.61
2.2
1.9
19.9
18.4
mg/l
—
5
24
8
50
1.60
0.61
1.0
1.1
—
—
—
0
0
70
601
1.17
0.61
1.7
1.7
0.0
0.3
iu/ml
—
8
124
38
308
1.24
0.59
1.2
1.1
26.6
96.5
iu/ml
—
10
84
14
197
0.71
0.59
1.3
1.6
—
—
—
0
0
10
64
1.57
0.58
1.0
1.2
—
—
—
0
0
146
1324
1.11
0.58
3.9
3.0
33.5
82.3
u/l
0.80
135
1190
5
87
0.57
0.56
1.4
1.4
—
71.6
—
0
11
210
1943
1.09
0.56
1.5
1.4
17.8
18.5
nmol/l
0.36
186
1748
41
339
1.21
0.55
2.7
2.4
324.4
162.5
ug/min
0.49
34
228
36
438
0.82
0.54
1.3
1.5
—
—
—
0
0
6
39
1.54
0.53
8.7
3.2
—
—
—
0
0
435
4146
1.06
0.53
4.2
3.5
9.4
9.7
mmol/l
0.70
397
3628
35
286
1.23
0.53
1.1
1.1
—
—
—
0
0
39
323
1.21
0.52
1.4
1.6
—
—
—
0
0
18
237
0.76
0.52
1.6
3.5
34.2
48.7
mg/l
0.85
13
190
6
40
1.50
0.51
1.0
1.4
—
64.0
—
0
5
53
453
1.17
0.51
1.2
1.1
2.6
2.0
u/ml
0.09
18
212
15
109
1.38
0.51
1.2
1.1
—
—
—
0
0
18
236
0.76
0.50
1.6
3.5
36.1
37.7
mg/l
0.05
12
189
30
243
1.24
0.49
2.0
1.6
—
—
—
0
0
16
120
1.34
0.46
3.9
2.6
—
91.1
—
0
17
128
1172
1.10
0.45
2.4
2.5
0.2
0.2
g/l
0.02
120
1082
27
219
1.24
0.45
1.1
1.1
98.4
103.3
%
0.33
27
210
5
31
1.61
0.43
1.0
1.1
—
—
—
0
0
81
728
1.12
0.41
5.8
5.3
50.6
14.5
ug/l
0.35
70
599
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.40
0.0
2.2
—
6.8
—
0
7
64
568
1.13
0.40
2.6
4.0
4.6
4.8
pmol/l
1.19
58
523
5
34
1.47
0.40
1.4
1.4
2.5
1.9
mg/l
—
5
26
17
132
1.29
0.40
1.1
1.1
—
—
—
0
0
337
3522
0.95
0.39
1.6
1.6
1.5
1.6
mmol/l
2.06
304
3101
39
335
1.17
0.38
1.2
1.3
3.8
3.7
mmol/l
0.12
39
316
18
225
0.80
0.38
1.2
1.1
—
—
—
0
0
14
107
1.31
0.37
3.3
3.0
—
—
—
0
0
5
37
1.35
0.37
1.4
1.8
7.1
8.8
ug/l
—
5
37
5
80
0.62
0.35
1.4
1.1
—
—
—
0
0
18
144
1.25
0.35
1.8
1.7
—
—
—
0
0
72
651
1.11
0.35
1.6
1.8
4.5
3.5
mg/l
0.22
48
436
147
1569
0.93
0.34
3.6
2.9
7.1
8.5
umol/l
0.59
138
1376
28
237
1.18
0.33
1.5
1.2
—
—
—
0
0
28
237
1.18
0.33
1.5
1.2
—
—
—
0
0
44
387
1.14
0.33
1.3
1.4
1322.7
533.4
mg/l
0.48
44
369
59
656
0.90
0.33
9.2
4.6
23.9
24.2
mmol/l
0.37
51
596
17
208
0.82
0.31
1.2
1.2
—
—
—
0
0
7
52
1.35
0.31
1.6
1.1
—
—
—
0
0
35
305
1.15
0.31
1.7
1.5
295.4
271.9
ug/g
0.25
21
180
12
151
0.79
0.28
1.2
1.3
—
—
—
0
0
9
116
0.77
0.27
2.7
2.9
—
—
—
0
0
9
120
0.75
0.27
2.3
1.7
—
—
—
0
0
124
1167
1.07
0.27
3.8
3.1
—
—
—
0
0
11
86
1.28
0.26
1.2
1.1
—
—
—
0
0
9
72
1.25
0.25
1.4
1.2
—
—
—
0
0
25
288
0.87
0.25
1.6
2.2
2.7
3.0
g/l
0.85
18
233
10
78
1.28
0.24
1.7
1.8
—
—
—
0
0
6
85
0.71
0.24
1.2
1.1
—
—
—
0
0
6
85
0.71
0.24
1.2
1.1
—
—
—
0
0
39
351
1.11
0.23
1.4
1.6
5799.8
1313.3
e6/l
0.39
34
285
39
351
1.11
0.23
1.3
1.6
32.5
26.8
e6/l
0.08
33
271
7
93
0.75
0.22
2.1
3.0
424.1
1252.2
u/ml
—
7
93
41
451
0.91
0.22
1.1
1.0
2.8
3.5
u/ml
—
7
74
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
1.9
—
0
8
62
576
1.08
0.20
1.5
1.5
—
—
—
0
0
27
303
0.89
0.20
1.6
2.1
6.4
6.9
g/l
0.77
18
236
27
303
0.89
0.20
1.6
2.1
4.0
4.0
g/l
0.06
18
222
27
303
0.89
0.20
1.6
2.1
—
—
—
0
0
6
48
1.25
0.20
1.3
1.1
—
—
—
0
0
67
717
0.93
0.20
4.1
2.8
141.5
146.9
ng/l
0.04
57
609
52
481
1.08
0.19
2.9
2.6
582.4
458.3
ug/l
0.25
52
460
38
346
1.10
0.19
1.1
1.1
1.0
4.9
u/ml
3.60
13
164
6
51
1.18
0.19
6.0
3.9
—
—
—
0
0
14
164
0.85
0.18
1.0
1.1
—
—
—
0
0
14
119
1.18
0.17
1.0
1.1
—
—
—
0
0
19
216
0.88
0.17
1.4
1.8
4.7
4.1
iu/l
—
6
70
56
523
1.07
0.17
1.5
1.8
—
—
—
0
0
13
110
1.18
0.17
4.5
2.9
0.2
0.2
e9/l
0.05
13
92
23
205
1.12
0.17
1.0
1.1
—
—
—
0
0
5
69
0.72
0.17
1.2
1.4
560.4
433.3
u/l
—
5
63
32
292
1.10
0.16
1.1
1.0
0.2
1.3
u/ml
—
6
72
32
296
1.08
0.13
1.2
1.2
—
—
—
0
0
125
1209
1.04
0.12
3.0
2.3
9.9
10.7
g/l
1.70
117
1114
1614
16077
1.02
0.12
11.2
11.1
43.1
43.2
%
0.17
1364
13776
17
189
0.90
0.12
1.1
1.2
—
—
—
0
0
13
114
1.14
0.11
4.6
2.9
574.2
610.6
e6/l
0.11
13
94
10
86
1.16
0.11
1.2
1.2
—
—
—
0
0
24
260
0.92
0.11
1.8
1.6
—
—
—
0
0
11
96
1.15
0.10
1.2
1.1
223.6
228.0
iu/ml
0.03
11
96
33
351
0.94
0.10
9.9
2.9
1.0
0.8
nmol/l
0.55
28
312
5
46
1.09
0.09
1.0
1.1
—
—
—
0
0
27
289
0.93
0.09
1.1
1.0
3.6
2.6
u/ml
0.28
16
166
5
48
1.04
0.09
1.0
1.0
—
—
—
0
0
6
54
1.11
0.09
4.3
4.0
—
—
—
0
0
67
694
0.96
0.08
1.3
2.2
40.8
39.5
u/l
0.20
61
632
17
156
1.09
0.08
1.4
1.2
—
—
—
0
0
33
347
0.95
0.07
2.4
1.7
—
—
—
0
0
8
78
1.03
0.07
1.5
2.0
172.0
186.2
u/l
—
8
78
9
100
0.90
0.06
1.6
1.1
—
—
—
0
0
9
100
0.90
0.06
1.6
1.1
—
—
—
0
0
9
100
0.90
0.06
1.8
2.3
—
—
—
0
0
9
104
0.86
0.06
2.1
2.3
913.7
704.4
ml
—
9
73
17
158
1.08
0.06
1.0
1.1
—
—
—
0
0
34
326
1.04
0.05
1.1
1.1
3.1
4.3
u/ml
0.34
14
152
16
165
0.97
0.00
1.4
1.2
—
—
—
0
0
38
385
0.99
0.00
3.1
1.9
—
—
—
0
0
41
412
1.00
0.00
1.1
1.1
0.7
2.8
u/ml
—
10
117
19
187
1.02
0.00
1.1
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.6
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
7.6
—
0.4
—
0
8
5
50
1.00
0.00
1.4
1.5
—
—
—
0
0
5
50
1.00
0.00
1.4
1.5
—
—
—
0
0
9
98
0.92
0.00
1.1
1.3
—
—
—
0
0
5
57
0.88
0.00
1.4
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
0.00
1.1
1.1
—
—
—
0
0
6
64
0.94
0.00
2.5
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
92
0.98
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
11184.2
—
0
6
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
26
260
1.00
0.00
1.2
1.2
—
12.2
—
0
11
5
49
1.02
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
8
86
0.93
0.00
1.0
1.1
—
—
—
0
0
8
87
0.92
0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
87
0.92
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_MALEINFERT and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_MALEINFERT | 0.764 [0.66, 0.88] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 310 out of 16070 males with N14_MALEINFERT died.
Mortality risk
Mortality risk for people of age
years, who have N14_MALEINFERT.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.133% |
| 5 | No data | 0.87% |
| 10 | No data | 2.112% |
| 15 | No data | 4.228% |
| 20 | No data | 7.232% |
Relationships between endpoints
↥Index endpoint: N14_MALEINFERT – Male infertility
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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