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Drug-induced hypoglycaemia without coma

EFO MESH Endpoint Browser PheWeb

E4_HYPODRUG

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E16.0#
  • Hospital discharge: ICD-9 — 2510A
  • Cause of death: ICD-10 — E16.0#
  • Cause of death: ICD-9 — 2510A

2 out of 7 registries used, show all original rules.

622

4. Check minimum number of events

None

622

5. Include endpoints

None

622

6. Filter based on genotype QC (FinnGen only)

603

Control definitions (FinnGen only)

Control exclude
E4_GLUCOPANCREAS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E16
Name in latin
Hypoglychaemia ex medicamento sine comate

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4342 1947 2352
Only index persons 3451 1539 1912
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.07
Only index persons 0.07 0.06 0.07
Median age at first event (years)
Whole population 67.85 72.85 63.76
Only index persons 67.13 71.38 63.71

-FinnGen-

Key figures

All Female Male
Number of individuals 603 251 352
Unadjusted period prevalence (%) 0.13 0.09 0.16
Median age at first event (years) 60.70 55.48 64.42

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
622
Matched controls
6220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H04AA01
ATC
glucagon; nasal, parenteral
51.2
323.3
195
55
A10AA01, ,
ATC
42.0
322.4
207
73
A10AE05
ATC
insulin detemir; parenteral
28.5
307.7
274
167
T89
ICPC
Diabetes insulin dependent
34.6
307.7
248
117
A10AC01
ATC
insulin (human); parenteral
36.0
307.7
407
311
A10AB05
ATC
insulin aspart; parenteral
40.8
307.7
405
272
A10AB01
ATC
insulin (human); parenteral
39.6
307.7
263
113
A10AE04
ATC
insulin glargine; parenteral
38.1
307.7
435
358
A10AA02, ,
ATC
32.8
307.7
240
117
E16.0
ICD-10 Finland
Drug-induced hypoglycaemia without coma
4503599627370496.0
307.7
568
*
103
Kela drug reimbursment
Diabetes, insulin-treated
77.1
307.7
588
1139
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
41.9
307.7
277
117
215
Kela drug reimbursment
Diabetes, non-insulin-treated
20.9
304.7
488
922
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
53.5
303.8
180
47
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
41.0
293.5
188
65
A10AB04
ATC
insulin lispro; parenteral
30.0
276.0
199
96
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
39.1
253.6
163
56
A10AE06
ATC
insulin degludec; parenteral
27.4
243.7
180
91
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
81.9
212.6
114
17
E10
ICD-10 Finland
Type 1 diabetes mellitus
36.9
197.0
127
43
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
13.7
178.1
194
199
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
53.9
166.1
96
21
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
24.4
161.8
121
61
H3603, E103,
ICD-10 Finland
69.2
152.9
84
14
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
36.9
152.2
97
31
XCK10
NOMESCO Finland
Photography of fundus of eye
9.7
151.5
225
345
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
856.4
142.9
135
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
7.4
139.4
365
1006
SPAT1262
SPAT
Handing over of treatment supplies
7.5
135.8
287
639
A10AD01
ATC
insulin (human); parenteral
20.6
130.3
104
60
H3600, E103,
ICD-10 Finland
44.4
129.5
78
20
177
Kela drug reimbursment
Insulin glargine 300 U / ml
21.0
120.7
95
53
H36.00
ICD-10 Finland
Diabetic background retinopathy
25.1
117.2
85
39
A10BB12
ATC
glimepiride; oral
8.6
111.3
168
256
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
13.1
109.1
113
104
CKC12
NOMESCO Finland
Photocoagulation of retina
12.7
108.0
114
108
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
50.0
107.7
63
14
T90
ICPC
Diabetes non-insulin dependent
5.7
102.2
298
861
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
53.2
100.6
58
12
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
61.4
99.9
56
10
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
39.7
98.6
61
17
A10BB01
ATC
glibenclamide; oral
9.6
95.0
124
157
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
15.7
93.8
85
62
H3601, E103,
ICD-10 Finland
36.1
92.9
59
18
H36.01
ICD-10 Finland
Diabetic maculopathy
21.5
92.4
71
37
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
54.3
87.1
50
10
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
6.2
83.5
177
377
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
22.8
80.4
60
29
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
14.9
79.8
74
56
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
12.0
77.7
83
79
A10BA02
ATC
metformin; oral
4.4
74.4
320
1200
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
39.4
71.1
44
12
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
9.8
69.7
86
100
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
19.9
67.1
53
29
H43.1
ICD-10 Finland
Vitreous haemorrhage
12.4
66.8
69
62
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
12.9
61.9
62
53
2510A
ICD-9 Finland
Other disorders of pancreatic internal secretion, Hypoglycaemic coma[HYPERINSULINAEMIA IATROGENEA SEU FACTITIA]
+∞
61.5
58
*
A10AD05
ATC
insulin aspart; parenteral
11.6
60.4
65
62
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
3.9
60.1
270
1014
H3601, E113,
ICD-10 Finland
14.2
59.5
56
43
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
6.4
59.2
109
199
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
8.4
56.8
79
106
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.2
55.9
200
636
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
11.5
54.0
58
55
H3600, E113,
ICD-10 Finland
17.2
53.4
45
28
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
11.3
52.5
57
55
E16.19
ICD-10 Finland
Other specified hypoglycaemia
283.3
51.9
52
*
A10AB06
ATC
insulin glulisine; parenteral
17.9
50.9
42
25
A10AA03, ,
ATC
15.1
49.8
45
32
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
9.9
48.5
58
64
C03CA01
ATC
furosemide; systemic
3.3
47.2
310
1436
T36
ICD-10 Finland
Poisoning by systemic antibiotics
7.5
46.8
71
105
2500A
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE,TYYPPI II]
8.0
46.2
66
91
SPAT1008
SPAT
Photography of fundus of the eye or interpretation of photograph
7.6
45.4
68
99
A11CC03
ATC
alfacalcidol; systemic
10.4
45.4
52
54
S97
ICPC
Chronic ulcer skin
5.4
45.1
98
207
NHQ40
NOMESCO Finland
Amputation of toe
11.7
44.7
47
43
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
6.3
44.5
81
145
SPAT1148
SPAT
Treatment of chronic ulcer or burn
4.0
44.2
155
478
CKC10
NOMESCO Finland
Local photocoagulation of retina
11.5
43.1
46
43
V03AE01
ATC
polystyrene sulfonate; oral
14.8
42.8
39
28
A10BH01
ATC
sitagliptin; oral
4.5
42.5
119
310
E11
ICD-10 Finland
Type 2 diabetes mellitus
3.7
41.5
168
570
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
4.3
41.1
124
342
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.8
40.5
153
495
C09AA02
ATC
enalapril; systemic
3.3
39.9
199
768
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
8.4
39.7
54
70
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
8.6
39.4
52
65
OAB50, ,
SPAT
5.9
38.2
74
140
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
53.7
38.1
45
9
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
13.1
37.8
37
30
TK800
NOMESCO Finland
Hemodialysis
9.4
36.7
45
51
Z49.1
ICD-10 Finland
Extracorporeal dialysis
13.8
36.0
34
26
XCW99
NOMESCO Finland
Other investigative procedure of eye
3.9
35.2
118
349
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
9.0
34.8
44
52
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
9.9
33.9
40
43
205
Kela drug reimbursment
Chronic hypertension
2.8
33.6
247
1170
A46
ICD-10 Finland
Erysipelas
3.4
33.5
150
536
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.2
33.5
174
680
A12AA04
ATC
calcium carbonate; oral
10.9
32.7
36
35
C02AC05
ATC
moxonidine; oral
5.6
32.6
65
126
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.0
31.2
71
155
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.8
30.8
59
110
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
30.7
159
617
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.0
30.5
172
700
N18.8
ICD-10 Finland
Other chronic renal failure
7.5
30.5
45
64
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
4.3
29.4
82
211
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
10.5
28.5
32
32
I50.9
ICD-10 Finland
Heart failure, unspecified
3.0
28.2
159
644
E87.5
ICD-10 Finland
Hyperkalaemia
8.0
27.5
38
50
C10AA01
ATC
simvastatin; oral
2.5
27.3
316
1823
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
4.1
27.1
81
219
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
78.8
27.0
30
*
A10BH05
ATC
linagliptin; oral
4.7
27.0
67
157
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.4
26.7
113
386
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
48.0
26.7
32
7
TPH07
NOMESCO Finland
Cathetrisation of artery
3.4
26.6
109
365
F10.09
ICD-10 Finland
Alcohol intoxication UNS
7.5
26.6
39
55
CL2S4, ,
SPAT
10.8
26.4
29
28
A10BX01
ATC
guar gum; oral
5.1
26.0
58
124
A10BB07
ATC
glipizide; oral
8.9
26.0
33
39
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
7.7
25.7
37
51
L04AA06
ATC
mycophenolic acid; systemic
9.8
25.5
30
32
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
4.8
24.8
59
133
B03XA02
ATC
darbepoetin alfa; parenteral
7.4
24.4
36
51
CKC15
NOMESCO Finland
Panretinal photocoagulation
20.5
23.7
35
18
CKD40
NOMESCO Finland
Endophotocoagulation of retina
8.5
23.7
31
38
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
10.0
23.4
27
28
ZXD05
NOMESCO Finland
Urgent procedure
2.4
23.2
242
1310
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.3
22.9
62
155
WX892
NOMESCO Finland
Monitored bed care
3.7
22.8
78
231
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.8
22.8
136
563
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
22.6
112
418
M65.3
ICD-10 Finland
Trigger finger
5.0
22.4
50
107
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.4
22.2
89
293
L84
ICD-10 Finland
Corns and callosities
5.4
22.0
45
89
H3602, E103,
ICD-10 Finland
119.2
21.7
23
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.7
21.7
74
219
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
45.1
21.6
26
6
H3603, E113,
ICD-10 Finland
18.3
21.5
33
19
A10AD04
ATC
insulin lispro; parenteral
35.2
21.3
27
8
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
21.2
170
812
C08CA01
ATC
amlodipine; oral
2.3
21.0
271
1589
J01FF01
ATC
clindamycin; systemic
2.4
21.0
201
1039
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.3
20.8
214
1141
R11
ICD-10 Finland
Nausea and vomiting
3.3
20.8
86
288
A10BG02
ATC
rosiglitazone; oral
8.1
20.6
28
36
Z94.0
ICD-10 Finland
Kidney transplant status
20.9
20.6
30
15
A28
ICPC
Limited function/disability NOS
2.6
20.3
147
667
171
Kela drug reimbursment
Degludekinsuliini
33.8
20.3
26
8
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.5
20.1
40
77
C09AA05
ATC
ramipril; oral
2.3
20.0
203
1074
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.8
19.7
46
102
I10
ICD-10 Finland
Essential (primary) hypertension
2.2
19.6
396
2751
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
4.1
19.6
56
146
B01AC04
ATC
clopidogrel; oral
2.5
19.4
146
674
RD210, ,
NOMESCO Finland
8.2
19.3
26
33
SPAT1054
SPAT
Examination of peripheral nervous system
8.2
19.3
26
33
G63.2
ICD-10 Finland
Diabetic polyneuropathy
27.0
19.3
26
10
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
20.9
19.2
28
14
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
23.4
19.2
27
12
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.3
19.1
195
1030
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
19.1
114
469
2507B
ICD-9 Finland
Diabetes mellitus, Diabetes with peripheral circulatory disorders[DIABETES MELLITUS CUM COMPLICAT ALIA ,TYYPPI I]
72.2
18.8
21
*
A10BJ06
ATC
semaglutide; parenteral
4.4
18.7
48
115
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.7
18.6
62
180
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
18.5
199
1072
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.2
18.4
238
1380
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.8
18.4
106
428
C10AA05
ATC
atorvastatin; oral
2.1
18.1
273
1677
T87
ICPC
Hypoglycaemia
54.2
18.1
21
*
C03DA01
ATC
spironolactone; oral
2.7
18.0
107
438
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
17.9
80
280
A41.9
ICD-10 Finland
Sepsis, unspecified
4.5
17.9
45
106
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
17.8
92
350
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.1
17.7
50
129
E10.01
ICD-10 Finland
Insulin-dependent diabetes diabetic coma with hyperglycemia
97.9
17.7
19
*
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
4.5
17.6
44
103
J01DA01
ATC
[U] cefalexin
2.1
17.6
404
2893
N30.0
ICD-10 Finland
Acute cystitis
2.6
17.6
114
488
S91.3
ICD-10 Finland
Open wound of other parts of foot
5.6
17.5
34
64
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
17.4
60
178
Z49.0
ICD-10 Finland
Preparatory care for dialysis
16.5
17.2
27
17
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.8
17.1
32
58
Z3231
NOMESCO Finland
Registered nurse
2.2
17.1
202
1126
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.1
16.9
48
124
L89
ICD-10 Finland
Decubitus ulcer and pressure area
6.5
16.9
28
45
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
65.2
16.8
19
*
SPAT1139
SPAT
Nutrition survey
5.0
16.8
37
78
C01DA14
ATC
isosorbide mononitrate; oral
2.4
16.8
146
716
J01MA12
ATC
levofloxacin; systemic
2.4
16.7
144
702
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
6.9
16.7
26
39
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
28.4
16.6
22
8
Z49.2
ICD-10 Finland
Other dialysis
23.8
16.5
23
10
J01MA02
ATC
ciprofloxacin; systemic
2.0
16.5
272
1712
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.6
16.5
114
503
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.2
16.3
173
920
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
6.7
16.3
26
40
Z2446
NOMESCO Finland
Social worker
3.3
16.3
65
212
C09BA02
ATC
enalapril and diuretics; systemic
3.1
16.3
74
261
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.4
16.2
63
202
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
5.5
16.2
32
61
ZXA10
NOMESCO Finland
Bilateral
2.4
16.2
140
684
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.6
16.1
106
456
AA1AD
NOMESCO Finland
CT of head and brain
2.1
15.9
197
1113
XF600
NOMESCO Finland
Bloodpressure measurement
3.5
15.9
58
179
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.6
15.8
107
466
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.2
15.8
164
863
N06AB04
ATC
citalopram; systemic
2.3
15.8
150
761
E66.00
ICD-10 Finland
Metabolic syndrome
3.8
15.8
50
140
SPAT1254
SPAT
Administration of medicine
2.4
15.7
122
567
SPAT1229
SPAT
Assessment of need for aid
3.1
15.6
68
234
MAA00
NOMESCO Finland
Amniocentesis
6.6
15.5
25
39
F10.24
ICD-10 Finland
Alcohol depence active use
7.2
15.4
23
33
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.4
15.3
39
93
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
18.3
15.2
23
13
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
15.2
128
616
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
15.2
95
398
127
Kela drug reimbursment
Transplant complication
11.2
15.1
28
26
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
15.1
226
1364
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
12.9
15.0
26
21
ZXA00
NOMESCO Finland
Right side
2.1
15.0
185
1040
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.1
14.9
205
1200
A10BH02
ATC
vildagliptin; oral
5.5
14.8
29
55
ZXA05
NOMESCO Finland
Left side
2.1
14.6
174
964
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
153.5
14.5
15
*
E86
ICD-10 Finland
Volume depletion
4.9
14.4
32
68
I50.0
ICD-10 Finland
Congestive heart failure
2.8
14.3
79
310
XCK20, ,
NOMESCO Finland
19.7
14.3
21
11
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.9
14.3
43
116
L03.9
ICD-10 Finland
Cellulitis, unspecified
6.4
14.3
24
39
C10AX09
ATC
ezetimibe; oral
2.4
14.3
110
508
ZX120
NOMESCO Finland
Intravenous
2.8
14.2
74
282
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
14.9
14.1
23
16
TQW11
NOMESCO Finland
Vacuum treatment of wound
5.6
14.1
27
50
N03AX16
ATC
[U] pregabalin
2.2
14.1
148
779
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.7
14.0
81
326
AN1
HP
Coronary angiography
2.5
13.9
98
434
L28
ICPC
Limited function/disability (L)
2.3
13.9
127
631
6480A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Diabetes mellitus
24.4
13.9
19
8
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
20.6
13.9
20
10
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.5
13.8
98
436
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.5
13.7
49
149
160
Kela drug reimbursment
exenatide
5.6
13.6
26
48
Z3226
NOMESCO Finland
Physiotherapist
2.2
13.5
132
674
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
5.7
13.5
25
45
C02EA02, ,
ATC
3.5
13.4
48
146
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
6.5
13.4
22
35
R4180
NOMESCO Finland
Podiatric therapy
10.8
13.3
25
24
WZC30
NOMESCO Finland
Teaching
2.3
13.3
111
530
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.7
13.3
79
322
TKC20
NOMESCO Finland
Catheterisation of bladder
2.9
13.2
66
245
V03AE02
ATC
sevelamer; oral
41.0
13.2
16
*
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.1
13.2
165
926
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
3.7
13.2
42
118
S18
ICPC
Laceration/cut
1.9
13.2
280
1883
AN4
HP
Balloon angioplasty and drug eluding stent
4.1
13.2
37
95
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.4
13.1
33
78
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.8
13.0
68
259
A10BD07
ATC
metformin and sitagliptin; systemic
3.9
12.9
38
101
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
12.9
291
1991
XCD20
NOMESCO Finland
Photoangiography of eye
5.9
12.8
23
40
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
12.8
231
1471
SPAT1240
SPAT
Therapeutic discussion
2.7
12.7
74
298
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
32.8
12.6
16
5
TBW99
NOMESCO Finland
Other minor procedure in endocrine surgery
32.8
12.6
16
5
E16.10
ICD-10 Finland
Hyperinsulinism
+∞
12.5
12
*
137
Kela drug reimbursment
Uraemia requiring dialysis
13.5
12.5
21
16
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
132.6
12.5
13
*
A06AD11
ATC
lactulose; oral
2.2
12.4
119
601
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
12.4
100
470
N02AA05
ATC
oxycodone; systemic
2.1
12.3
131
690
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
4.6
12.2
29
65
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
12.2
160
910
SPAT1263
SPAT
Sampling
1.8
12.2
263
1765
L04AD02
ATC
tacrolimus; systemic
16.3
12.2
19
12
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.1
12.2
34
87
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.4
12.1
31
74
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
12.1
70
281
R53
ICD-10 Finland
Malaise and fatigue
2.0
12.1
176
1039
R41.0
ICD-10 Finland
Disorientation, unspecified
3.9
11.9
35
93
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
6.0
11.9
21
36
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
11.9
110
548
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
4.4
11.9
30
71
B05DA
ATC
Isotonic solutions
15.0
11.9
19
13
K08.3
ICD-10 Finland
Retained dental root
2.8
11.8
60
225
BEF00, ,
SPAT
16.8
11.7
18
11
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
19.4
11.6
17
9
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.2
11.6
107
531
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.9
11.6
34
90
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
9.5
11.6
23
25
S91.1
ICD-10 Finland
Open wound of toe(s) without damage to nail
5.8
11.5
21
37
SPAT1301
SPAT
No procedures
1.9
11.5
201
1257
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
4.8
11.5
26
56
E16.9
ICD-10 Finland
Disorder of pancreatic internal secretion, unspecified
+∞
11.5
11
*
A10BK01
ATC
dapagliflozin; oral
2.9
11.4
55
200
C10AA07
ATC
rosuvastatin; oral
1.9
11.4
180
1088
N19
ICD-10 Finland
Unspecified kidney failure
3.6
11.4
38
110
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.6
11.4
39
115
L17
ICPC
Foot/toe symptom/complaint
1.9
11.4
175
1050
Z13.1
ICD-10 Finland
Special screening examination for diabetes mellitus
5.3
11.3
23
45
N18.0
ICD-10 Finland
End-stage renal disease
9.9
11.3
22
23
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
9.9
11.3
22
23
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
11.3
111
565
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
11.3
77
335
S20
ICPC
Corn/callosity
4.7
11.3
26
57
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.8
11.2
35
97
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
11.4
11.1
20
18
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.6
11.1
65
263
WX140
NOMESCO Finland
Parabulbar anesthesy
3.4
11.0
41
128
ZXE00
NOMESCO Finland
One hour or less
1.8
11.0
240
1606
N03AX12
ATC
[U] gabapentin; oral
2.2
10.9
108
551
WX213
NOMESCO Finland
Lower leg blockade
15.8
10.9
17
11
B05DB
ATC
Hypertonic solutions
15.8
10.9
17
11
N06AX21
ATC
duloxetine; oral
2.5
10.9
75
328
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.7
10.7
60
237
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
61.1
10.7
12
*
K85
ICD-10 Finland
Acute pancreatitis
5.4
10.7
21
40
N06AA09
ATC
amitriptyline; systemic
2.6
10.6
64
262
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.7
10.6
61
244
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.5
10.6
37
111
J01DB01
ATC
cefalexin; oral
2.0
10.5
498
4164
R33
ICD-10 Finland
Retention of urine
2.4
10.5
74
327
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
10.5
233
1562
RJ521, ,
NOMESCO Finland
111.8
10.4
11
*
H3603, E107,
ICD-10 Finland
111.8
10.4
11
*
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.5
10.4
36
107
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
16.4
10.4
16
10
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.7
10.3
24
53
N03AG01
ATC
valproic acid; systemic, rectal
2.9
10.2
49
178
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
8.1
10.2
22
28
N03AX09
ATC
lamotrigine; oral
3.3
10.2
38
119
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
10.1
163
987
N05AF03
ATC
chlorprothixene; systemic
4.6
10.1
24
54
SPAT1310
SPAT
Counselling related to known health issue
1.8
10.1
193
1234
C07AG02
ATC
carvedilol; oral
2.8
10.0
52
197
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
14.9
10.0
16
11
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
14.9
10.0
16
11
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
10.0
59
239
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
40.8
10.0
12
*
N02AX02
ATC
tramadol; systemic, rectal
1.7
10.0
263
1844
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.0
10.0
45
158
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.2
9.9
87
422
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.3
9.9
37
116
P15
ICPC
Chronic alcohol abuse
3.9
9.9
29
77
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.9
9.9
147
868
E13.7
ICD-10 Finland
Other specified diabetes mellitus, with multiple complications
26.5
9.8
13
5
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
9.8
126
707
C08CA02
ATC
felodipine; oral
2.4
9.8
71
318
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
55.9
9.7
11
*
ACC51
NOMESCO Finland
Release of median nerve
2.7
9.7
52
201
N05AH04
ATC
quetiapine; oral
2.0
9.7
121
673
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
5.1
9.6
20
40
C09AA01
ATC
captopril; oral
4.7
9.6
22
48
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
9.3
9.6
19
21
N05CD07
ATC
temazepam; oral
2.2
9.5
89
443
SPAT1216
SPAT
Assessment of functional ability
2.1
9.5
107
572
SPAT1255
SPAT
Intravenous administration of medicine
2.7
9.5
52
203
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.3
9.5
76
355
R60.0
ICD-10 Finland
Localized oedema
2.3
9.4
79
376
N05CF01
ATC
zopiclone; oral
1.8
9.4
204
1348
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.2
9.4
87
431
H25.1
ICD-10 Finland
Senile nuclear cataract
1.8
9.4
184
1180
2503B
ICD-9 Finland
Diabetes mellitus, Diabetes with other coma[SOKERITAUDIN AIHEUTTAMA MUNUAISSAIRAUS,TYYPPI I]
+∞
9.4
9
*
2510B
ICD-9 Finland
Other disorders of pancreatic internal secretion, Hypoglycaemic coma[COMA HYPOGLYCAEMICUM]
+∞
9.4
9
*
M04AA01
ATC
allopurinol; systemic
2.1
9.4
98
510
WX730
NOMESCO Finland
Conventional respirator
8.9
9.3
19
22
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
9.7
9.3
18
19
C03AA03
ATC
hydrochlorothiazide; oral
2.4
9.3
66
292
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
9.3
116
644
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
3.7
9.2
29
81
SPAT1172
SPAT
Guidance concerning hydration
4.4
9.2
23
54
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.5
9.2
32
96
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
3.9
9.1
27
72
OAB42, ,
SPAT
2.3
9.1
69
314
UJF32
NOMESCO Finland
Coloscopy
1.8
9.1
155
953
2500X
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,NUD]
15.9
9.1
14
9
E87.2
ICD-10 Finland
Acidosis
15.9
9.1
14
9
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.7
9.1
50
196
M14.6
ICD-10 Finland
Neuropathic arthropathy
37.3
9.0
11
*
SPAT1260
SPAT
Consultation of another employee
2.0
9.0
113
628
N05BA01
ATC
diazepam; systemic, rectal
2.1
9.0
86
432
K05.31
ICD-10 Finland
Periodontitis pronounced
2.3
9.0
68
310
N07BB01
ATC
disulfiram; oral
3.2
9.0
36
118
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
24.4
8.9
12
5
CK2S4, ,
SPAT
8.1
8.9
19
24
K92.0
ICD-10 Finland
Haematemesis
3.9
8.9
26
69
J01EA01
ATC
trimethoprim; systemic
1.8
8.8
156
968
A10BX02
ATC
repaglinide; oral
7.3
8.8
20
28
D01AC02
ATC
miconazole; topical
2.4
8.8
60
261
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
14.3
8.7
14
10
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
14.3
8.7
14
10
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.3
8.7
22
52
E11.01
ICD-10 Finland
Non-insulin dependent diabetes diabetic coma with hyperglycaemia
50.7
8.7
10
*
371
Kela drug reimbursment
Degludekinsuliini
50.7
8.7
10
*
SPAT1359
SPAT
Use of symptom diary
4.5
8.7
21
48
N06AX16
ATC
venlafaxine; oral
2.1
8.7
83
417
N05BA04
ATC
oxazepam; oral
1.8
8.6
163
1031
RS221, ,
NOMESCO Finland
7.1
8.6
20
29
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
8.6
205
1386
C08CA13
ATC
lercanidipine; oral
2.1
8.6
88
454
NH2AA
NOMESCO Finland
Heel X-ray examination
13.0
8.4
14
11
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
8.7
8.3
17
20
K90.0
ICD-10 Finland
Coeliac disease
3.9
8.3
24
63
S17
ICPC
Abrasion/scratch/blister
3.9
8.3
24
63
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.5
8.3
55
236
N05AA02
ATC
levomepromazine; systemic
3.1
8.3
34
113
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
4.3
8.3
21
50
A41.8
ICD-10 Finland
Other specified sepsis
4.3
8.3
21
50
4019X
ICD-9 Finland
Essential hypertension, Unspecified
3.2
8.2
33
108
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
4.0
8.2
23
59
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
11.9
8.1
14
12
3AC01, ,
NOMESCO Finland
10.2
8.1
15
15
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
7.4
8.0
18
25
J02AC01
ATC
fluconazole; systemic
1.7
8.0
192
1296
S01.0
ICD-10 Finland
Open wound of scalp
2.3
7.9
61
280
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
7.9
7.9
17
22
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
7.9
7.9
17
22
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.3
7.9
30
95
Y94.0
ICD-10 Finland
Accident at home
4.1
7.9
21
52
NGQ20
NOMESCO Finland
Amputation of lower leg
8.6
7.8
16
19
E0000UV, ,
ATC
1.6
7.8
235
1680
C07AB07
ATC
bisoprolol; oral
1.6
7.8
294
2223
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.3
7.8
29
91
ZZA00
NOMESCO Finland
Split skin graft
3.4
7.7
27
81
E13.1
ICD-10 Finland
Other specified diabetes mellitus, with ketoacidosis
45.6
7.7
9
*
M86.8
ICD-10 Finland
Other osteomyelitis
45.6
7.7
9
*
E13
ICD-10 Finland
Other specified diabetes mellitus
45.6
7.7
9
*
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.2
7.7
63
297
S19
ICPC
Skin injury other
3.1
7.7
31
102
E000001, ,
ATC
1.8
7.6
118
700
B03XA01
ATC
erythropoietin; parenteral
8.2
7.6
16
20
N17.8
ICD-10 Finland
Other acute renal failure
8.2
7.6
16
20
R50.9
ICD-10 Finland
Fever, unspecified
1.9
7.6
99
555
QDB99
NOMESCO Finland
Other procedure for wound of skin of lower limb
18.6
7.6
11
6
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
12.0
7.6
13
11
T82
ICPC
Obesity
3.4
7.6
27
82
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.7
7.6
42
165
F54
ICD-10 Finland
Psychological and behavioural factors associated with disorders or diseases classified elsewhere
25.4
7.6
10
*
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
3.9
7.6
22
58
W19
ICD-10 Finland
Unspecified fall
2.2
7.6
69
340
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.2
7.5
30
98
N30.9
ICD-10 Finland
Cystitis, unspecified
2.6
7.5
44
178
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.3
7.5
60
280
I95.9
ICD-10 Finland
Hypotension, unspecified
4.5
7.5
18
41
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.7
7.4
40
155
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
7.4
43
173
F05.9
ICD-10 Finland
Delirium, unspecified
4.1
7.4
20
50
SPAT1167
SPAT
Insertion of urinary catheter
3.2
7.4
29
94
N06AB03
ATC
fluoxetine; oral
2.1
7.3
76
393
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.3
7.3
54
243
R10.0
ICD-10 Finland
Acute abdomen
3.6
7.3
24
69
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
7.0
7.3
17
25
I50.1
ICD-10 Finland
Left ventricular failure
2.6
7.3
42
168
RJ411, ,
NOMESCO Finland
11.0
7.3
13
12
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
3.9
7.3
21
55
E932D
ICD-9 Finland
Hormones and synthetic substitutes[INSULIINI]
+∞
7.3
7
*
E13.6
ICD-10 Finland
Other specified diabetes mellitus, with other specified complications
+∞
7.3
7
*
SPAT1251
SPAT
Organisation of medication
3.0
7.3
32
111
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
7.2
209
1473
TQW80
NOMESCO Finland
Local dermatologic skincare
3.8
7.2
22
60
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.1
7.2
68
339
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
4.0
7.2
20
51
N05AH03
ATC
olanzapine; systemic
2.5
7.2
46
194
WW200
NOMESCO Finland
Immunization
3.6
7.2
23
65
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.4
7.2
48
207
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.7
7.2
39
152
RJ414, ,
NOMESCO Finland
30.4
7.2
9
*
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
20.3
7.1
10
5
I79.2*E11.5
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
20.3
7.1
10
5
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
7.1
228
1647
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
7.1
58
273
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
12.2
7.1
12
10
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
12.2
7.1
12
10
WX002
NOMESCO Finland
Sedation and analgesia
1.8
7.1
113
676
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
7.1
185
1270
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
7.1
117
708
C10AA04
ATC
fluvastatin; oral
2.2
7.1
61
294
H26.2
ICD-10 Finland
Complicated cataract
7.1
7.0
16
23
H26.02
ICD-10 Finland
Presenil cataract
3.9
7.0
20
52
A07AA02
ATC
nystatin; oral
2.6
7.0
39
154
I25.2
ICD-10 Finland
Old myocardial infarction
2.2
7.0
58
275
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
7.0
103
602
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
6.9
294
2264
R4180, ,
SPAT
7.7
6.9
15
20
TK820
NOMESCO Finland
Peritoneal dialysis
14.0
6.9
11
8
W84
ICPC
Pregnancy high risk
3.5
6.9
23
67
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.7
6.9
146
948
SPAT1211
SPAT
Application of soft bandage
2.2
6.9
57
270
C07AB02
ATC
metoprolol; systemic
1.7
6.9
132
834
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.8
6.8
16
24
A07AA09
ATC
vancomycin; oral
6.8
6.8
16
24
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
6.8
6.8
16
24
C09CA01
ATC
losartan; oral
1.7
6.8
149
976
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
5.8
6.8
18
32
K86.0
ICD-10 Finland
Alcohol-induced chronic pancreatitis
40.5
6.8
8
*
2505B
ICD-9 Finland
Diabetes mellitus, Diabetes with ophthalmic manifestations[NEUROPATHIA DIABETICA,TYYPPI I]
40.5
6.8
8
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
40.5
6.8
8
*
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
16.9
6.8
10
6
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.5
6.8
23
68
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
7.3
6.7
15
21
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
6.7
162
1089
N02AC04
ATC
dextropropoxyphene; oral
2.8
6.6
33
123
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
6.6
395
3272
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
8.8
6.6
13
15
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.3
6.5
18
558
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
6.5
216
1566
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
5.4
6.5
18
34
EBA00
NOMESCO Finland
Extraction of tooth
1.6
6.5
204
1461
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.6
6.5
21
60
H16.0
ICD-10 Finland
Corneal ulcer
2.5
6.5
39
160
SPAT1234
SPAT
Support of social functional capacity
2.5
6.5
39
160
P03
ICPC
Feeling depressed
2.2
6.5
56
270
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.1
6.4
61
305
RJ511, ,
NOMESCO Finland
70.5
6.4
7
*
S92.3
ICD-10 Finland
Fracture of metatarsal bone
3.1
6.4
26
86
2507A
ICD-9 Finland
Diabetes mellitus, Diabetes with peripheral circulatory disorders[DIABETES MELLITUS CUM COMPLICAT ALIA ,TYYPPI II]
14.5
6.4
10
7
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.3
6.4
48
218
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
6.4
115
712
NB6AA
NOMESCO Finland
Humerus X-ray examination
3.8
6.4
19
51
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.7
6.4
148
982
R60.9
ICD-10 Finland
Oedema, unspecified
2.6
6.4
35
137
D06AX01
ATC
fusidic acid; topical
2.1
6.4
63
320
H26.4
ICD-10 Finland
After-cataract
2.1
6.4
63
320
SPAT1281
SPAT
Other administrative function
2.3
6.4
50
232
N03AF01
ATC
carbamazepine; oral, rectal
2.5
6.3
38
156
N07BA03
ATC
varenicline; oral
2.8
6.3
30
109
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.9
6.3
18
47
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
3.9
6.3
18
47
FNC30
NOMESCO Finland
Aorto-coronary venous bypass with three distal anastomoses
3.9
6.3
18
47
M10.9
ICD-10 Finland
Gout, unspecified
2.2
6.3
50
233
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.4
6.3
44
194
25009
ICD-8 Finland
Diabetes mellitus, Unspecified
18.2
6.3
9
5
T89, ,
ICD-10 Finland
+∞
6.3
6
*
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
+∞
6.3
6
*
E14.1
ICD-10 Finland
Unspecified diabetes mellitus, with ketoacidosis
27.0
6.2
8
*
25008
ICD-8 Finland
Diabetes mellitus, Complicatio alia definita
27.0
6.2
8
*
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
27.0
6.2
8
*
H3602, E113,
ICD-10 Finland
27.0
6.2
8
*
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.7
6.2
19
52
40199
ICD-8 Finland
Essential benign hypertension
3.7
6.2
19
52
JN4AD
NOMESCO Finland
Body CT examination
2.1
6.2
60
302
SPAT1360
SPAT
Extensive global examination
2.4
6.2
42
182
Z72.0
ICD-10 Finland
Tobacco use
3.6
6.2
20
57
U14
ICPC
Kidney symptom/complaint
5.4
6.2
17
32
C10AB02
ATC
bezafibrate; oral
5.4
6.2
17
32
A01
ICPC
Pain general/multiple sites
2.1
6.1
57
283
A10BK03
ATC
empagliflozin; oral
2.0
6.1
63
325
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
6.1
69
368
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.8
6.1
18
48
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.2
6.1
24
78
NH3CG
NOMESCO Finland
Extensive MRI of foot
12.7
6.1
10
8
WX872
NOMESCO Finland
Intensive care
2.5
6.1
37
153
Z51.4
ICD-10 Finland
Preparatory care for subsequent treatment, not elsewhere classified
6.8
6.1
14
21
B01AB04
ATC
dalteparin; parenteral
2.6
6.1
35
141
F10.25
ICD-10 Finland
Alcohol dependence continuous use
5.3
6.0
17
33
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.0
6.0
70
377
K59.0
ICD-10 Finland
Constipation
2.3
6.0
43
191
H25.8
ICD-10 Finland
Other senile cataract
1.9
6.0
72
392
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
6.1
6.0
15
25
SPAT1151
SPAT
Treatment of major wounds
6.1
6.0
15
25
NFJ54
NOMESCO Finland
Internal fixation of fracture of upper femur with intramedullary nail
3.9
6.0
17
44
N06AX11
ATC
mirtazapine; oral
1.6
6.0
191
1367
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.9
6.0
27
95

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
424
1300
8.10
146.51
5.4
3.3
197.27
198.58
mg/l
0.00
327
882
435
1387
8.11
143.59
6.8
3.8
22.17
11.07
mg/mmol
2.46
333
902
426
1444
7.19
127.70
5.3
3.1
6.78
7.84
mmol/l
4.89
361
1221
200
617
4.30
58.58
12.6
5.6
1.14
1.03
mmol/l
4.95
188
562
89
140
7.25
55.68
2.8
2.3
144.59
100.29
ug/min
0.40
55
84
164
469
4.39
52.64
8.3
3.8
1.30
1.96
mmol/l
1.39
143
374
163
469
4.35
51.83
8.1
3.8
6.02
5.78
kpa
2.64
157
456
174
563
3.90
46.58
2.4
1.6
—
—
—
0
0
146
418
4.26
46.34
14.5
7.0
13.68
10.14
mmol/l
5.18
140
392
135
390
4.14
42.05
6.3
3.2
5.00
4.54
kpa
1.19
129
377
118
323
4.27
39.38
7.5
3.9
123.33
82.75
ng/l
3.55
106
285
182
674
3.40
38.94
4.8
2.4
2.07
2.31
g/l
7.01
171
624
131
391
3.98
38.80
14.6
7.9
—
—
—
0
0
191
739
3.29
37.92
4.7
2.4
10.44
13.00
umol/l
6.69
178
685
448
2795
3.16
37.12
11.7
4.8
10.03
6.76
mmol/l
37.02
425
2612
56
85
7.14
35.86
6.8
3.9
—
—
—
0
0
171
639
3.31
35.72
5.2
2.4
20.26
22.81
%
1.88
143
552
184
739
3.12
33.83
3.8
3.1
0.80
0.82
mmol/l
1.15
168
693
57
98
6.30
32.37
6.2
1.3
0.52
0.87
nmol/l
2.89
41
87
271
1385
2.70
31.29
7.5
4.2
—
—
—
0
0
250
1229
2.73
31.17
2.6
2.1
3.04
3.05
mg/l
0.02
212
1048
345
2000
2.63
30.56
8.6
4.9
32.22
35.41
g/l
15.78
320
1853
218
1009
2.79
30.46
1.8
1.2
2.48
1.24
u/ml
0.48
69
269
169
695
2.97
29.32
3.7
2.1
—
—
—
0
0
144
560
3.04
27.44
2.2
2.6
1.81
1.80
%
0.03
122
507
52
97
5.76
27.11
6.9
3.9
—
—
—
0
0
103
330
3.54
26.96
5.4
3.6
5.07
5.16
kpa
0.41
96
317
102
326
3.55
26.79
5.4
3.6
7.40
7.40
ph
0.14
25
25
311
1809
2.44
26.04
3.2
2.2
69.92
75.84
nmol/l
2.84
270
1608
34
43
8.31
25.36
3.9
2.7
—
—
—
0
0
139
559
2.91
24.73
9.3
7.8
0.60
1.18
mmol/l
0.59
116
437
191
913
2.58
24.17
2.0
1.7
1202.31
1193.60
nmol/l
0.04
142
688
112
409
3.12
23.56
1.6
2.0
417.61
378.17
nmol/l
1.07
103
373
45
86
5.56
22.82
4.3
2.7
—
—
—
0
0
43
79
5.77
22.73
5.3
2.5
15.63
15.94
%
0.18
30
36
356
2288
2.30
22.57
17.0
6.6
1.20
1.21
mmol/l
2.71
304
1944
335
2102
2.29
22.47
15.4
5.8
1.20
1.21
mmol/l
2.23
307
1905
253
1420
2.32
22.05
3.8
3.1
—
—
—
0
0
134
560
2.78
21.98
9.6
7.7
5.34
5.07
kpa
1.66
125
528
134
560
2.78
21.98
9.6
7.7
11.65
11.98
kpa
0.35
125
531
124
511
2.78
20.81
9.9
8.2
94.22
95.58
%
1.12
118
488
322
2035
2.21
20.63
4.8
2.7
135.11
135.18
ug/l
0.00
291
1870
47
106
4.71
19.73
3.0
4.0
29.02
35.81
umol/l
1.52
41
93
251
1467
2.19
19.23
6.0
2.5
71.26
115.08
u/l
0.35
227
1370
208
1137
2.25
18.72
2.0
1.7
1.34
1.37
mmol/l
0.22
172
947
71
227
3.40
18.43
7.3
3.1
0.60
0.66
%
0.67
71
227
69
221
3.39
17.85
1.7
1.9
1.60
1.48
g/l
0.46
62
195
334
2222
2.09
17.83
19.8
16.3
1.22
1.31
inr
1.00
102
626
37
74
5.25
17.83
1.1
1.1
79.72
17.11
iu/ml
—
6
18
191
1027
2.24
17.75
4.3
2.7
5.67
4.45
e6/l
0.92
180
912
187
1002
2.24
17.49
5.0
3.0
465.19
574.83
mosm/kgh2o
8.30
167
852
238
1407
2.12
17.31
2.6
2.1
256.73
288.61
u/l
0.15
223
1323
40
88
4.79
17.28
4.1
2.2
123.38
127.08
g/l
0.38
34
61
232
1367
2.11
16.95
10.1
3.8
7.39
7.40
ph
0.71
54
240
73
254
3.12
16.47
11.8
10.9
—
—
—
0
0
26
41
6.57
15.94
2.5
2.5
633.76
545.16
ml
0.42
17
25
170
906
2.21
15.91
1.5
1.4
2.63
2.49
g/l
0.31
91
550
350
2433
2.00
15.84
7.1
6.2
10.07
11.93
umol/l
2.24
332
2304
40
96
4.38
15.53
8.7
4.4
3.30
2.44
mmol/l
1.07
33
62
40
98
4.29
15.13
1.7
1.3
—
—
—
0
0
518
4210
2.38
14.83
15.6
5.7
61.75
40.11
mmol/mol
115.48
487
3904
95
403
2.60
14.80
2.0
2.6
69.24
69.48
e9/l
0.02
69
314
83
334
2.71
14.34
1.3
1.2
—
—
—
0
0
37
89
4.36
14.32
1.8
1.3
89.67
105.17
u/ml
—
6
18
120
577
2.34
14.22
2.3
1.6
—
—
—
0
0
6
503
0.11
14.02
1.2
1.7
—
—
—
0
0
19
9
21.72
13.40
2.2
1.2
—
—
—
0
0
25
46
5.62
13.16
2.4
2.7
1.48
1.85
g/24h
0.22
11
22
225
1410
1.93
13.13
4.0
3.0
4213.83
1687.02
ng/l
2.58
192
1197
279
1881
1.88
12.97
2.6
2.0
96.83
93.46
pmol/l
0.50
139
1009
81
340
2.59
12.83
4.8
5.7
—
—
—
0
0
233
1489
1.90
12.74
5.5
3.3
76.23
103.00
e6/l
0.18
209
1153
436
3423
1.92
12.16
4.7
3.6
14.83
14.79
pmol/l
0.13
403
3082
171
998
1.98
12.14
2.0
1.7
480.01
6859627.83
pmol/l
0.50
140
831
404
3107
1.86
11.89
6.7
4.4
2910.49
2957.20
e6/l
0.01
16
56
40
117
3.59
11.86
1.9
1.3
197.44
312.04
ug/g
2.05
20
62
271
1865
1.80
11.36
6.7
3.7
72.48
40.64
ng/l
1.38
216
1311
449
3597
1.89
11.29
11.3
7.4
97.82
78.45
u/l
3.94
429
3361
138
772
2.01
10.93
2.3
1.6
—
—
—
0
0
82
373
2.38
10.90
2.0
2.6
64.91
66.25
g/l
0.46
71
337
251
1708
1.79
10.79
5.9
3.7
103.01
121.57
e6/l
0.12
216
1217
90
430
2.28
10.68
2.4
2.4
0.18
0.21
g/l
2.63
80
399
22
44
5.15
10.59
1.1
1.3
—
—
—
0
0
15
8
19.17
10.30
10.3
12.6
3.88
6.85
mmol/l
—
15
8
33
94
3.65
10.18
1.5
1.1
277.81
261.89
u/ml
0.10
21
55
186
1175
1.83
10.12
7.6
3.8
88.45
87.94
%
0.09
181
1151
192
1225
1.82
10.11
3.5
2.6
4230.47
7936.19
umol/l
0.61
164
1069
205
1339
1.79
9.96
5.2
3.1
0.54
0.54
e6/l
0.02
181
1013
14
7
20.42
9.84
6.8
4.1
—
—
—
0
0
500
4225
1.94
9.71
6.6
4.4
2.43
1.91
mu/l
0.58
463
3838
27
69
4.05
9.68
1.6
1.4
27.45
29.84
g/l
0.40
22
58
197
1284
1.78
9.57
5.0
3.1
—
—
—
0
0
411
3284
1.74
9.51
6.5
4.2
—
—
—
0
0
225
1529
1.74
9.43
4.0
3.3
2.32
2.35
mmol/l
2.08
194
1346
228
1570
1.71
9.03
4.2
3.4
36.78
33.26
u/l
0.45
217
1500
177
1142
1.77
8.79
1.7
1.5
19.70
19.90
nmol/l
0.06
149
977
155
963
1.81
8.74
2.3
1.9
—
—
—
0
0
23
57
4.15
8.59
1.5
1.2
5617.06
2134.66
e6/l
0.40
17
38
48
191
2.64
8.45
7.2
4.4
—
—
—
0
0
65
299
2.31
8.40
1.4
2.4
—
—
—
0
0
22
55
4.11
8.13
3.7
1.8
89.77
89.87
%
0.04
22
55
14
12
11.90
8.10
2.1
1.6
—
—
—
0
0
213
1475
1.68
8.07
3.4
2.4
—
—
—
0
0
100
554
1.96
7.99
3.7
2.8
9.62
9.55
umol/l
0.01
86
481
27
81
3.44
7.74
8.0
2.7
—
—
—
0
0
38
141
2.81
7.65
1.4
3.7
125.88
105.03
mg/l
0.12
31
115
38
141
2.81
7.65
1.4
3.7
61.58
32.05
mg/l
1.87
31
117
345
2719
1.60
7.61
8.4
8.7
4.91
4.20
e9/l
4.58
310
2378
149
949
1.75
7.61
4.5
3.6
269.27
352.00
ng/l
0.28
129
729
49
209
2.46
7.49
2.3
1.9
4.92
2.95
ug/l
0.33
44
181
82
433
2.03
7.49
5.0
2.3
28.25
33.47
u/l
0.71
63
360
19
32
6.09
7.43
2.4
2.6
545.92
488.81
min
0.89
13
21
293
2232
1.59
7.39
7.8
6.0
8.83
8.69
%
0.32
274
2091
37
139
2.77
7.29
1.4
3.7
83.25
2.40
ratio
—
6
14
314
2445
1.57
7.11
6.9
5.8
0.21
0.19
e9/l
0.75
277
2157
304
2354
1.57
7.03
6.8
5.5
0.05
0.04
e9/l
1.93
270
2051
288
2205
1.57
6.98
7.3
6.1
—
—
—
0
0
283
2163
1.57
6.88
7.2
5.7
0.66
0.64
%
0.31
264
2018
54
251
2.26
6.82
6.1
3.7
—
—
—
0
0
289
2224
1.56
6.79
7.4
5.6
2.86
2.84
%
0.05
270
2078
29
99
3.02
6.78
1.4
4.0
—
—
—
0
0
69
355
2.06
6.76
8.4
3.8
1.20
1.23
mmol/l
3.12
59
307
302
2350
1.55
6.73
6.8
5.5
0.64
0.60
e9/l
2.26
269
2040
283
2172
1.56
6.70
3.5
2.6
—
—
—
0
0
39
158
2.57
6.65
5.9
8.9
1.46
1.34
mmol/l
0.41
34
139
290
2247
1.54
6.53
7.5
5.6
60.72
57.75
%
4.29
274
2114
294
2288
1.54
6.47
7.5
5.8
24.21
27.26
%
5.22
275
2149
5
279
0.17
6.37
2.6
1.3
—
—
—
0
0
19
52
3.74
6.24
1.5
1.3
73188.45
34433.75
e6/l
0.29
11
28
25
83
3.10
6.14
2.0
1.2
49.35
64.14
mmol/l
1.86
20
70
305
2411
1.52
6.13
6.9
5.6
1.76
1.89
e9/l
1.24
275
2146
18
48
3.83
6.12
1.3
1.1
—
—
—
0
0
38
161
2.45
5.92
1.4
1.2
—
—
—
0
0
177
1249
1.58
5.91
6.6
3.8
0.00
0.01
estimate
0.69
65
405
77
435
1.88
5.77
2.1
2.5
7.73
7.71
ug/l
0.00
64
385
169
1186
1.58
5.76
6.8
6.2
—
—
—
0
0
17
46
3.77
5.68
1.5
1.3
—
—
—
0
0
17
46
3.77
5.68
1.1
1.2
—
—
—
0
0
531
4792
1.74
5.62
42.3
16.8
138.14
139.59
mmol/l
28.15
521
4650
9
7
13.02
5.59
1.6
1.6
—
—
—
0
0
69
381
1.91
5.54
7.7
3.6
—
—
—
0
0
531
4806
1.72
5.38
42.9
16.9
4.08
3.98
mmol/l
12.56
519
4660
290
2318
1.47
5.25
5.6
3.6
0.00
0.00
estimate
0.50
75
452
17
49
3.54
5.20
2.2
2.5
—
—
—
0
0
117
773
1.63
5.06
4.2
2.9
3.70
1.96
e6/l
1.08
75
440
18
55
3.34
5.06
1.6
1.4
—
—
—
0
0
91
566
1.71
4.95
1.3
1.3
668.57
462.14
titre
0.24
14
112
16
46
3.54
4.92
1.3
1.2
—
—
—
0
0
179
1316
1.51
4.84
6.3
4.0
—
—
—
0
0
128
874
1.58
4.83
3.2
3.1
2.48
2.45
mmol/l
1.79
107
758
23
84
2.80
4.82
1.3
1.5
—
—
—
0
0
285
2297
1.44
4.80
7.0
4.9
0.00
0.00
estimate
-0.00
75
422
9
10
9.11
4.79
1.0
1.1
—
—
—
0
0
87
544
1.70
4.64
1.9
1.5
—
—
—
0
0
17
454
0.36
4.58
1.1
1.3
—
—
—
0
0
9
11
8.28
4.57
1.0
1.0
—
—
—
0
0
154
1110
1.51
4.54
3.4
2.3
—
—
—
0
0
65
376
1.81
4.54
1.9
1.5
—
—
—
0
0
397
3424
1.44
4.50
4.7
3.8
19.99
12.09
mm/h
10.65
354
3147
38
183
2.15
4.46
4.8
3.8
1.68
1.28
mmol/l
1.28
38
178
11
19
5.87
4.46
5.8
2.3
64.00
81.18
umol/l
—
5
11
37
177
2.16
4.42
2.9
3.4
0.74
0.23
g/l
1.84
17
71
7
6
11.78
4.28
1.1
1.0
—
—
—
0
0
284
2323
1.41
4.25
5.8
3.6
0.04
0.00
estimate
0.49
55
400
10
17
5.96
4.14
3.3
2.5
—
—
—
0
0
259
2093
1.41
4.12
17.5
9.0
0.00
0.00
e9/l
0.06
213
1707
234
1873
1.40
3.88
4.5
3.4
5.90
5.84
ph
—
5
149
12
28
4.35
3.83
3.8
1.5
—
—
—
0
0
17
60
2.88
3.82
1.6
1.5
—
—
—
0
0
25
108
2.37
3.80
1.1
1.4
450.36
461.83
mg/l
0.06
25
103
369
3203
1.37
3.64
5.0
3.8
—
—
—
0
0
71
453
1.64
3.52
2.5
4.3
8.21
41.00
ug/l
1.07
62
379
6
6
10.08
3.50
1.3
1.3
—
—
—
0
0
29
139
2.14
3.49
3.9
3.4
—
—
—
0
0
57
344
1.72
3.48
4.1
4.3
0.00
0.12
%
2.83
24
113
515
4751
1.49
3.45
34.4
14.4
26.19
24.77
mg/l
0.44
454
3750
60
369
1.69
3.42
3.9
4.2
0.59
0.99
%
1.11
27
139
13
42
3.14
3.38
1.0
2.2
—
—
—
0
0
31
155
2.05
3.36
1.3
2.6
10.53
10.56
g/l
0.02
21
138
29
142
2.09
3.32
1.1
2.5
35.19
37.99
g/l
1.07
19
126
503
4631
1.45
3.29
7.5
4.6
2.14
2.69
mmol/l
41.59
468
4249
83
566
1.54
3.13
1.4
1.3
—
—
—
0
0
46
270
1.76
3.11
5.6
3.2
0.31
0.27
e6/l
0.11
46
263
11
30
3.71
3.10
2.2
1.5
90.73
77.87
umol/l
0.38
11
30
13
45
2.93
3.04
1.5
1.7
—
—
—
0
0
5
5
10.07
2.98
1.8
1.4
—
—
—
0
0
16
63
2.58
2.98
1.8
2.0
—
—
—
0
0
134
1015
1.41
2.96
1.8
1.7
1.28
1.20
mg/l
0.09
102
768
53
329
1.67
2.95
4.2
4.4
0.00
0.17
%
1.26
19
101
55
346
1.65
2.91
1.4
2.4
13.27
10.64
g/l
0.87
48
312
9
22
4.14
2.89
1.9
1.2
—
—
—
0
0
11
33
3.37
2.82
3.1
5.8
9.84
12.15
%
1.51
11
33
8
18
4.49
2.80
2.1
2.8
65125.00
35022.50
ug/l
—
8
18
42
249
1.74
2.77
3.0
3.5
4.04
4.64
pmol/l
2.69
35
221
165
1308
1.36
2.76
5.9
3.2
—
—
—
0
0
29
153
1.94
2.75
11.5
10.7
—
—
—
0
0
52
328
1.64
2.73
4.0
4.3
0.41
0.59
%
0.47
22
116
6
10
6.05
2.70
1.0
2.9
—
—
—
0
0
6
10
6.05
2.70
1.8
1.8
—
—
—
0
0
11
35
3.18
2.65
1.3
1.0
—
—
—
0
0
59
388
1.58
2.63
4.1
3.3
—
—
—
0
0
30
163
1.88
2.62
1.2
2.2
21.54
21.33
s
0.09
24
147
472
4353
1.35
2.61
5.8
3.8
1.32
1.28
mmol/l
0.37
420
3976
20
96
2.12
2.45
1.4
1.6
—
—
—
0
0
7
193
0.36
2.43
1.4
1.6
—
—
—
0
0
16
70
2.32
2.43
3.3
1.3
—
—
—
0
0
9
27
3.37
2.40
4.4
2.4
—
—
—
0
0
44
276
1.64
2.39
1.2
1.7
1.20
1.64
g/l
0.79
38
254
5
8
6.29
2.37
28.2
9.3
—
—
—
0
0
26
143
1.85
2.22
3.9
5.1
—
—
—
0
0
13
54
2.44
2.21
1.5
1.8
30.23
33.11
pg
1.15
13
54
13
54
2.44
2.21
1.8
4.5
—
—
—
0
0
486
4542
1.32
2.17
6.5
4.2
4.01
4.53
mmol/l
24.56
445
4202
60
415
1.49
2.16
8.7
4.0
—
—
—
0
0
7
19
3.71
2.15
6.4
12.5
—
—
—
0
0
9
30
3.03
2.15
1.6
1.5
—
—
—
0
0
10
36
2.81
2.14
1.6
1.6
—
—
—
0
0
8
25
3.23
2.10
1.1
1.2
1.95
1.87
mmol/l
—
8
25
14
62
2.29
2.09
1.5
3.2
—
—
—
0
0
482
4508
1.31
2.08
6.7
4.2
1.38
1.41
mmol/l
0.48
439
4140
5
10
5.03
2.07
1.2
1.1
—
—
—
0
0
16
76
2.13
2.04
3.2
2.7
4.26
4.06
mmol/l
0.83
16
76
16
76
2.13
2.04
3.2
2.7
105.31
105.66
mmol/l
0.10
16
76
9
32
2.84
2.00
1.3
1.3
—
—
—
0
0
38
244
1.59
1.92
4.8
4.1
—
—
—
0
0
7
22
3.21
1.88
3.9
3.3
28.43
35.93
umol/l
—
7
14
131
1061
1.30
1.85
5.7
3.9
1.02
1.02
kg/l
0.53
26
154
25
145
1.75
1.84
1.2
1.4
56.17
246.46
miu/ml
—
6
75
5
12
4.19
1.82
2.2
5.4
59.50
47.33
%
—
5
12
15
73
2.08
1.82
3.3
2.7
—
—
—
0
0
8
29
2.78
1.79
2.6
1.7
11.38
9.33
mmol/l
—
8
29
346
3140
1.23
1.79
5.0
3.1
65.91
48.92
u/l
1.86
316
2941
524
4989
1.32
1.75
16.7
9.9
25.52
27.15
u/l
0.71
508
4821
30
187
1.63
1.72
3.4
1.8
—
—
—
0
0
35
230
1.55
1.63
2.2
2.5
—
—
—
0
0
518
4942
1.29
1.57
33.1
13.6
—
—
—
0
0
17
93
1.85
1.53
2.0
1.3
—
—
—
0
0
5
15
3.35
1.52
2.6
2.6
—
—
—
0
0
6
21
2.87
1.51
1.2
1.0
134.67
181.13
mmol/24h
—
6
21
127
1052
1.26
1.50
4.5
3.6
—
—
—
0
0
19
109
1.77
1.48
3.4
2.4
—
—
—
0
0
7
28
2.52
1.45
1.7
3.9
—
—
—
0
0
91
1124
0.78
1.43
2.8
2.9
0.65
0.78
ug/l
1.02
66
715
39
272
1.46
1.41
1.3
1.2
129.57
172.92
iu/ml
0.36
21
101
5
17
2.96
1.36
1.4
1.4
8.00
21.24
umol/l
—
5
17
27
176
1.56
1.34
2.6
2.0
—
—
—
0
0
422
4459
0.83
1.32
6.2
4.3
8.95
5.98
mmol/l
38.68
375
4044
9
43
2.11
1.30
1.3
1.2
—
—
—
0
0
25
162
1.57
1.28
2.3
2.3
62.39
4668.56
u/l
—
9
63
32
221
1.47
1.24
2.6
1.9
—
—
—
0
0
9
45
2.01
1.23
1.0
1.3
—
—
—
0
0
10
187
0.53
1.20
1.1
1.1
—
—
—
0
0
32
223
1.46
1.19
2.6
1.8
—
—
—
0
0
32
223
1.46
1.19
2.6
1.9
—
—
—
0
0
5
20
2.51
1.15
1.2
1.6
—
—
—
0
0
30
209
1.46
1.12
2.6
1.9
—
—
—
0
0
8
40
2.01
1.12
1.3
1.3
—
—
—
0
0
433
4108
1.18
1.10
38.3
17.1
14.63
14.85
%
0.44
428
4042
18
112
1.63
1.10
4.3
4.1
25.78
27.17
mg/l
0.07
13
74
8
41
1.96
1.09
1.0
1.1
—
—
—
0
0
7
32
2.20
1.08
1.1
1.2
—
—
—
0
0
66
527
1.28
1.08
1.7
1.7
—
—
—
0
0
14
82
1.72
1.06
1.1
1.5
—
—
—
0
0
35
472
0.73
1.05
1.4
1.5
—
—
—
0
0
23
154
1.51
1.05
3.3
2.7
—
—
—
0
0
40
299
1.36
1.03
4.4
2.7
—
—
—
0
0
7
35
2.01
1.00
1.9
3.5
—
—
—
0
0
14
84
1.68
0.98
1.0
1.0
—
—
—
0
0
7
36
1.95
0.97
3.9
3.1
—
—
—
0
0
9
50
1.81
0.97
3.8
3.2
—
—
—
0
0
38
288
1.34
0.92
2.2
2.4
—
18.34
—
0
19
15
94
1.61
0.91
1.0
1.1
—
—
—
0
0
17
111
1.55
0.88
2.4
1.8
8.63
7.11
iu/l
—
7
34
22
153
1.45
0.87
1.5
1.6
—
—
—
0
0
30
222
1.37
0.85
2.7
1.7
—
—
—
0
0
0
26
0.00
0.78
0.0
1.3
—
—
—
0
0
27
200
1.37
0.77
1.2
1.3
—
—
—
0
0
178
1949
0.88
0.75
4.4
4.8
2.38
3.02
ug/l
0.37
144
1727
5
24
2.09
0.74
1.6
1.4
—
—
—
0
0
36
456
0.78
0.74
1.6
2.2
10.31
13.31
nmol/l
1.83
30
404
5
25
2.01
0.73
1.0
1.0
—
—
—
0
0
9
58
1.56
0.70
1.2
1.2
—
—
—
0
0
147
1621
0.88
0.69
5.2
2.8
—
—
—
0
0
5
28
1.79
0.66
1.0
1.0
—
—
—
0
0
6
102
0.58
0.62
2.8
1.7
4958.00
17260.68
e6/l
—
6
76
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
19
140
1.37
0.59
1.0
1.2
—
—
—
0
0
38
311
1.24
0.57
4.9
3.2
13.91
5.56
e9/l
0.42
28
257
16
115
1.40
0.57
1.4
1.3
—
—
—
0
0
6
36
1.67
0.57
1.0
1.2
—
—
—
0
0
13
180
0.72
0.52
1.1
1.1
—
—
—
0
0
7
48
1.46
0.47
1.0
1.3
—
—
nmol/l
—
0
0
13
176
0.73
0.46
1.5
1.8
34.92
40.45
nmol/l
0.68
13
168
537
5278
1.13
0.45
46.8
21.0
37.74
40.32
%
14.73
490
4926
537
5278
1.13
0.45
45.6
20.9
253.97
243.91
e9/l
2.98
528
5138
537
5280
1.12
0.44
45.6
20.8
90.59
90.86
fl
0.68
531
5193
31
257
1.22
0.44
1.3
1.3
—
55.24
—
0
18
537
5281
1.12
0.43
45.6
20.8
30.02
30.31
pg
3.23
531
5193
537
5282
1.12
0.42
45.8
20.8
4.27
4.52
e12/l
18.52
526
5124
537
5284
1.12
0.41
46.3
21.0
126.95
136.14
g/l
27.13
529
5191
537
5284
1.12
0.41
45.9
20.9
7.46
6.82
e9/l
10.43
526
5125
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
14
106
1.33
0.39
4.9
2.3
—
—
—
0
0
79
718
1.11
0.37
1.3
1.3
26.00
34.65
iu/ml
0.50
26
223
9
71
1.27
0.36
1.6
3.0
—
—
—
0
0
45
511
0.87
0.36
1.3
1.3
—
—
—
0
0
7
54
1.30
0.30
1.0
1.3
—
—
—
0
0
60
547
1.11
0.28
1.8
2.4
117.33
127.26
ug/g
0.12
44
434
8
62
1.29
0.28
1.0
1.1
—
—
—
0
0
9
117
0.77
0.27
1.3
1.4
—
—
—
0
0
9
118
0.76
0.27
1.3
1.4
—
—
—
0
0
9
121
0.74
0.27
1.3
1.5
—
—
—
0
0
30
262
1.15
0.27
1.4
1.2
—
—
—
0
0
24
208
1.16
0.24
2.5
2.8
—
—
—
0
0
50
458
1.10
0.23
1.3
1.4
—
—
—
0
0
182
1754
1.05
0.22
2.2
2.1
—
—
—
0
0
5
42
1.19
0.21
1.4
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.7
—
1.05
—
0
13
6
48
1.25
0.20
1.0
3.3
33.35
6.98
nmol/l
—
6
48
40
365
1.10
0.20
1.5
1.4
—
—
—
0
0
6
53
1.13
0.18
1.2
1.1
—
—
—
0
0
7
61
1.15
0.17
2.3
1.5
—
—
—
0
0
18
157
1.15
0.17
1.5
1.1
—
—
—
0
0
72
691
1.05
0.11
1.4
1.3
25.86
10.17
u/ml
0.60
22
261
5
44
1.14
0.10
1.0
2.0
0.77
1.26
e9/l
—
5
38
129
1322
0.97
0.09
1.5
1.5
—
—
—
0
0
32
302
1.06
0.08
1.4
1.4
—
—
—
0
0
7
66
1.06
0.08
1.6
2.5
3.76
5.96
umol/l
—
7
50
6
71
0.84
0.07
2.2
1.6
—
—
—
0
0
28
265
1.06
0.07
1.2
1.2
—
—
—
0
0
10
111
0.90
0.06
1.0
1.1
—
—
—
0
0
54
556
0.97
0.05
1.2
1.3
—
—
—
0
0
18
170
1.06
0.04
1.9
2.6
36.54
50.50
u/ml
0.34
18
164
7
76
0.92
0.00
1.6
1.3
—
—
—
0
0
9
98
0.92
-0.00
1.8
1.3
—
—
—
0
0
5
58
0.86
-0.00
1.2
2.2
—
—
—
0
0
8
85
0.94
-0.00
1.5
1.7
—
—
—
0
0
8
80
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
39.50
—
0
8
8
81
0.99
-0.00
1.0
1.1
—
—
—
0
0
5
55
0.91
-0.00
1.4
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
1.92
—
0
8
0
5
0.00
-0.00
0.0
8.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
5.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
5
52
0.96
-0.00
1.2
2.9
43.60
32.82
u/ml
—
5
52
5
53
0.94
-0.00
3.4
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint E4_HYPODRUG and mortality.

Females

Parameter HR [95% CI] p-value
E4_HYPODRUG 3.179 [2.59, 3.9] < 0.001
Birth year 0.997 [0.99, 1.01] 0.425

During the follow-up period (1.1.1998 — 31.12.2019), 810 out of 1499 females with E4_HYPODRUG died.

Males

Parameter HR [95% CI] p-value
E4_HYPODRUG 4.327 [3.31, 5.66] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 853 out of 1762 males with E4_HYPODRUG died.

Mortality risk

Mortality risk for people of age

years, who have E4_HYPODRUG.

N-year risk Females Males
1 0.291% 0.724%
5 1.778% 4.777%
10 4.592% 11.687%
15 9.211% 21.543%
20 16.109% 34.332%

Relationships between endpoints

↥

Index endpoint: E4_HYPODRUG – Drug-induced hypoglycaemia without coma

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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