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Malignant neoplasm of kidney, except renal pelvis

C3_KIDNEY_NOTRENALPELVIS

kidney neoplasm: A benign or malignant neoplasm affecting the kidney. Representative examples of benign renal neoplasms include fibroma, lipoma, oncocytoma, and juxtaglomerular cell tumor. Representative examples of malignant renal neoplasms include renal cell carcinoma, renal pelvis carcinoma, Wilms tumor, rhabdoid tumor, sarcoma, and lymphoma.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C64
  • Cause of death: ICD-9 1890
  • Cause of death: ICD-8 1890
  • Cancer registry: Topography ICD-O-3 C64
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

3414

4. Check minimum number of events

None

3414

5. Include endpoints

3414

6. Filter based on genotype QC (FinnGen only)

3414

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Similar endpoints

List of similar endpoints to Malignant neoplasm of kidney, except renal pelvis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 3414 1230 2184
Unadjusted period prevalence (%) 0.77 0.42 0.96
Median age at first event (years) 66.29 65.45 66.76

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3137
Matched controls
31366
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
KAC10
NOMESCO Finland
Total nephrectomy with capsule
740.8
323.0
826
15
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
323.0
1413
*
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
2953.5
323.0
729
*
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
323.0
1013
*
KAD00
NOMESCO Finland
Partial nephrectomy
388.2
323.0
402
12
KAD01
NOMESCO Finland
Percutaneous endoscopic partial nephrectomy
306.0
323.0
377
14
JN4AD
NOMESCO Finland
Body CT examination
8.0
323.0
825
1345
197
Kela drug reimbursment
Sunitinib
537.6
323.0
338
7
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
261.3
323.0
1990
207
8260/3-C64.9
ICD-O-3
Papillary adenocarcinoma, NOS, of kidney, NOS
+∞
323.0
325
*
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
449.0
323.0
621
17
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
4715.2
323.0
2811
53
B01AB10
ATC
tinzaparin; parenteral
8.4
301.3
733
1104
L01XE04
ATC
[U] sunitinib; oral
1010.3
286.9
277
*
130
Kela drug reimbursment
Malignant tumour
6.2
263.3
806
1654
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
33.1
262.4
349
118
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.0
241.9
921
2411
WX302
NOMESCO Finland
Thoracal epidural anesthesy
8.4
226.3
536
748
JN4CD
NOMESCO Finland
Very extensive body CT
9.2
220.6
493
623
JN4BD
NOMESCO Finland
Extensive body CT
4.7
210.0
829
2210
1502
Kela drug reimbursment
Cabozantinib
1020.4
198.1
192
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
6.7
197.4
549
960
3012
Kela drug reimbursment
Cabozantinib
975.1
189.6
184
*
KAC00
NOMESCO Finland
Nephrectomy
113.5
186.6
202
19
C64.80
ICD-10 Finland
Wilms tumour
385.1
183.6
183
5
TPH07
NOMESCO Finland
Cathetrisation of artery
4.5
183.2
748
2030
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
30.9
176.2
238
83
159
Kela drug reimbursment
Pazopanib
863.0
168.4
164
*
U75
ICPC
Malignant neoplasm of kidney
177.3
161.3
168
10
8317/3-C64.9
ICD-O-3
Renal cell carcinoma, chromophobe type of kidney, NOS
+∞
159.7
152
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
14.7
153.1
265
195
7125
FHL
Nephrectomy (extrrafascial)
1559.3
151.2
146
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
144.9
1205
5569
322
Kela drug reimbursment
Sunitinib
670.3
131.5
129
*
L01XE26
ATC
[U] cabozantinib; oral
+∞
129.0
123
*
B01AB05
ATC
enoxaparin; parenteral
2.6
122.4
1310
6852
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
7.1
119.2
310
478
L01XE11
ATC
[U] pazopanib; oral
599.9
117.9
116
*
8000/3-C64.9
ICD-O-3
Neoplasm, malignant of kidney, NOS
+∞
113.2
108
*
1890B
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,ADENOCARCINOMA]
+∞
111.1
106
*
N02AX02
ATC
tramadol; systemic, rectal
2.3
106.6
1631
10024
L01EX07
ATC
cabozantinib; oral
535.3
105.3
104
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
102.4
1714
10906
158
Kela drug reimbursment
Everolimus
513.9
101.1
100
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.0
100.3
702
2784
180
Kela drug reimbursment
Interferon alfa
40.3
98.1
124
32
KA1AE
NOMESCO Finland
Kidney ultrasound examination
7.2
91.8
235
351
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.6
82.2
406
1233
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
5.2
80.9
268
555
WX402
NOMESCO Finland
General anaesthesia
2.7
79.4
645
2760
WF049
NOMESCO Finland
Radiotherapy of metastasis
5.3
76.0
246
495
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
5.0
75.0
258
556
168
Kela drug reimbursment
Axitinib
+∞
74.2
71
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.3
73.2
402
1321
KA3LT
NOMESCO Finland
Njurlesion coagulation
90.0
71.2
79
9
WZC30
NOMESCO Finland
Teaching
2.6
69.2
569
2431
D30.0
ICD-10 Finland
Benign neoplasm: Kidney
16.2
67.5
111
71
A03FA01
ATC
metoclopramide; systemic, rectal
2.3
66.3
755
3819
L01XE10
ATC
[U] everolimus; oral
318.1
62.6
63
*
N02AA05
ATC
oxycodone; systemic
2.4
61.9
645
3108
KAC01
NOMESCO Finland
Percutaneous endoscopic nephrectomy
128.5
59.0
63
5
R31
ICD-10 Finland
Unspecified haematuria
2.5
58.1
527
2355
1890X
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,EI HIST VAHV]
578.3
57.8
57
*
343
Kela drug reimbursment
Pazopanib
+∞
57.5
55
*
U14
ICPC
Kidney symptom/complaint
8.6
57.4
128
154
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.9
56.5
1071
6627
C648
ICD-10 Finland
NA
+∞
56.4
54
*
N02BE01
ATC
paracetamol; systemic, rectal
2.2
56.1
2672
22816
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
6.2
55.9
157
265
L01XE17
ATC
[U] axitinib; oral
+∞
55.4
53
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
54.8
1239
8139
N18.8
ICD-10 Finland
Other chronic renal failure
4.4
51.7
197
469
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
9.8
48.5
100
105
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.0
47.9
298
1054
UKC02
NOMESCO Finland
Cystoscopy
2.0
47.5
716
4007
C08CA01
ATC
amlodipine; oral
1.8
46.6
1339
9358
L01EX01
ATC
sunitinib; oral
238.4
46.1
47
*
R4110
NOMESCO Finland
Physiotherapy
1.9
45.9
902
5561
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.9
45.6
155
328
8960/3-C64.9
ICD-O-3
Nephroblastoma, NOS, of kidney, NOS
+∞
44.9
43
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
44.4
754
4400
A11CC03
ATC
alfacalcidol; systemic
5.0
44.2
147
304
D41.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Renal pelvis
21.4
44.0
65
31
TK800
NOMESCO Finland
Hemodialysis
5.2
44.0
142
284
340
Kela drug reimbursment
Everolimus
433.3
43.3
43
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
42.2
425
1979
Z51.5
ICD-10 Finland
Palliative care
2.8
42.1
299
1150
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.9
41.3
139
291
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
40.0
333
1404
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
39.9
632
3575
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
4.8
39.9
138
298
XX3DW
NOMESCO Finland
Time consuming IT work
2.3
39.8
393
1810
361
Kela drug reimbursment
Axitinib
+∞
38.6
37
*
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
9.5
37.9
79
85
C65
ICD-10 Finland
Malignant neoplasm of renal pelvis
19.0
36.6
56
30
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
19.6
35.7
54
28
PHE70
NOMESCO Finland
Thrombectomy of inferior vena cava
+∞
35.5
34
*
M04AA01
ATC
allopurinol; systemic
1.9
34.5
557
3150
205
Kela drug reimbursment
Chronic hypertension
1.6
33.7
1103
7787
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
33.7
259
1039
1890A
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,NEPHROBLASTOMA]
+∞
33.4
32
*
V03AE01
ATC
polystyrene sulfonate; oral
6.0
32.6
92
157
198
Kela drug reimbursment
Sorafenib
18.4
31.8
49
27
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
7.5
31.6
76
104
GD1AD
NOMESCO Finland
Thorax CT examination
2.9
31.3
202
731
ZXA05
NOMESCO Finland
Left side
1.7
30.2
856
5768
KA4AT
NOMESCO Finland
Cytology of kidney with ultrasound guidance
58.9
30.1
35
6
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
9.4
29.8
62
67
KH1CD
NOMESCO Finland
Very extensive urinary tract ultrasound examination
5.6
29.7
88
160
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
9.8
29.6
60
62
A12AA04
ATC
calcium carbonate; oral
5.0
29.4
97
200
BCA30
NOMESCO Finland
Unilateral adrenalectomy
27.0
29.3
40
15
S18
ICPC
Laceration/cut
1.5
28.9
1318
9999
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.5
28.1
232
970
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
27.9
1965
16406
18900
ICD-8 Finland
Malignant neoplasm of other and unspecified urinary organs, Kidney, except pelvis
146.2
27.7
29
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
4.1
27.6
111
279
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
27.3
1158
8604
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
8.5
27.2
60
72
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.7
27.0
188
711
Z49.0
ICD-10 Finland
Preparatory care for dialysis
6.5
27.0
71
111
SPAT1153
SPAT
Removal of sutures
1.6
26.7
1013
7319
C03CA01
ATC
furosemide; systemic
1.5
26.5
1084
7971
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
5.9
26.3
74
127
N28.1
ICD-10 Finland
Cyst of kidney
4.8
26.2
89
190
8010/3-C64.9
ICD-O-3
Carcinoma, NOS, of kidney, NOS
+∞
26.1
25
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.5
25.8
212
884
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
25.6
401
2228
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
25.4
530
3242
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
6.0
25.2
70
118
L03AA04
ATC
NA
16.2
24.9
40
25
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
4.5
24.9
90
205
WX704
NOMESCO Finland
Intubation
2.3
24.8
245
1121
N18.0
ICD-10 Finland
End-stage renal disease
5.3
24.5
76
147
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
8.8
24.2
52
60
WW500
NOMESCO Finland
Blood transfusion
2.7
24.1
167
630
Z85.5
ICD-10 Finland
Personal history of malignant neoplasm of urinary tract
56.4
24.0
28
5
L01EX03
ATC
pazopanib; oral
+∞
24.0
23
*
L01XE05
ATC
[U] sorafenib; oral
17.8
23.9
37
21
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
4.9
23.8
79
165
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.6
23.6
185
748
ZXA00
NOMESCO Finland
Right side
1.5
23.0
872
6248
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.8
23.0
78
167
Z90.5
ICD-10 Finland
Acquired absence of kidney
65.4
22.8
26
*
PC5DT
NOMESCO Finland
Embolisation of tumor of kidney
120.9
22.6
24
*
R50.9
ICD-10 Finland
Fever, unspecified
1.8
22.2
430
2560
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
10.4
22.0
43
42
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.5
22.0
173
705
KA3CT
NOMESCO Finland
Biopsy of kidney under CT guidance
+∞
21.9
21
*
KB1CG
NOMESCO Finland
Extensive MRI examination of urinary tract with high intensity magnet
62.9
21.9
25
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.4
21.8
197
861
2395A
ICD-9 Finland
Neoplasm of unspecified nature, Other genito-urinary organs
18.5
21.7
33
18
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.3
21.4
198
876
B03XA02
ATC
darbepoetin alfa; parenteral
3.7
21.1
93
255
J01MA02
ATC
ciprofloxacin; systemic
1.5
21.0
1194
9295
L03AB04
ATC
interferon alfa-2a; parenteral
16.7
20.9
33
20
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
20.7
913
6737
C79.7
ICD-10 Finland
Secondary malignant neoplasm of adrenal gland
22.5
20.4
29
13
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
20.1
537
3507
PHN71
NOMESCO Finland
Excision of tumor mass from inferior vena cava
+∞
19.8
19
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.4
19.8
177
772
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
11.0
19.6
37
34
L03AB05
ATC
interferon alfa-2b; parenteral
10.1
19.3
38
38
WX110
NOMESCO Finland
Local anesthesy
1.4
19.2
1800
15309
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.8
18.9
354
2080
H02AB02
ATC
dexamethasone; systemic
1.9
18.9
315
1779
L01EK01
ATC
axitinib; oral
+∞
18.8
18
*
C02AC05
ATC
moxonidine; oral
2.3
18.6
182
828
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.5
18.5
48
75
M05BX04
ATC
denosumab; parenteral
2.3
17.8
174
790
WX725
NOMESCO Finland
Noninvasive ventilation
2.4
17.7
155
668
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.1
17.7
195
938
137
Kela drug reimbursment
Uraemia requiring dialysis
5.5
17.3
51
94
KH1AD
NOMESCO Finland
CT of urinary organs
2.7
17.1
119
454
D41.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Urinary organ, unspecified
25.7
16.9
23
9
H05BX01
ATC
cinacalcet; oral
7.6
16.9
39
52
PJD43
NOMESCO Finland
Excision of aortic lymph nodes
22.0
16.8
24
11
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.1
16.8
66
165
M907, C6488
ICD-10 Finland
NA
+∞
16.7
16
*
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
10.4
16.6
32
31
RJ128
NOMESCO Finland
NA
15.1
16.6
27
18
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.4
16.5
80
239
A02BC02
ATC
pantoprazole; systemic
1.4
16.4
1855
16079
C08CA02
ATC
felodipine; oral
1.7
16.3
338
2045
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
2.1
16.2
185
905
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
5.3
15.9
48
92
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
2.9
15.8
98
349
U79
ICPC
Neoplasm urinary tract unspecified
60.3
15.8
18
*
ZXC96
NOMESCO Finland
Robot assisted procedure
2.7
15.7
111
427
Z94.0
ICD-10 Finland
Kidney transplant status
4.7
15.6
52
111
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
7.8
15.5
35
45
ZX120
NOMESCO Finland
Intravenous
1.8
15.5
292
1717
V03AE02
ATC
sevelamer; oral
8.0
15.3
34
43
KAC20
NOMESCO Finland
Nephroureterectomy
17.8
15.1
23
13
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.2
15.0
150
691
Z31.5
ICD-10 Finland
Genetic counselling
2.7
15.0
101
378
196
Kela drug reimbursment
Paricalcitol and cinacalcet
8.5
14.9
32
38
A10BH05
ATC
linagliptin; oral
2.1
14.9
176
873
J01MA12
ATC
levofloxacin; systemic
1.5
14.8
576
4095
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
14.3
402
2645
ZXD05
NOMESCO Finland
Urgent procedure
1.4
14.1
839
6472
Z3226
NOMESCO Finland
Physiotherapist
1.5
14.0
523
3677
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.5
13.9
485
3362
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
2.5
13.8
109
449
R4190
NOMESCO Finland
Nutritional therapy
2.7
13.7
94
356
E87.5
ICD-10 Finland
Hyperkalaemia
3.1
13.6
73
237
B05DA
ATC
Isotonic solutions
5.4
13.6
40
75
C08CA13
ATC
lercanidipine; oral
1.6
13.6
415
2787
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
8.3
13.5
29
35
7124
FHL
Nephrectomy (simple
140.5
13.5
14
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
3.5
13.0
60
174
321
Kela drug reimbursment
Paricalcitol and cinacalcet
6.3
12.7
33
53
WX290
NOMESCO Finland
Other blockade of nerve
1.4
12.7
912
7239
XKD00
NOMESCO Finland
Uroflowmetry
1.4
12.7
599
4413
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.6
12.5
91
359
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
10.1
12.5
24
24
L01EG02
ATC
everolimus; oral (mammalian target of rapamycin kinase inhibitors (mtor))
130.5
12.4
13
*
C68.9
ICD-10 Finland
Malignant neoplasm: Urinary organ, unspecified
130.5
12.4
13
*
B01AB04
ATC
dalteparin; parenteral
2.0
12.4
155
789
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.9
12.3
184
999
127
Kela drug reimbursment
Transplant complication
3.5
12.2
55
157
A06AD11
ATC
lactulose; oral
1.5
12.1
463
3265
C07AB02
ATC
metoprolol; systemic
1.4
12.1
674
5120
J01DB01
ATC
cefalexin; oral
1.3
12.1
2262
20649
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
12.0
188
1040
L02AB02
ATC
medroxyprogesterone; systemic (progestogens)
6.2
12.0
31
50
Z49.2
ICD-10 Finland
Other dialysis
5.0
11.7
36
72
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
5.5
11.6
33
60
U06
ICPC
Haematuria
2.5
11.6
89
363
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
3.9
11.5
46
119
JN6AD
NOMESCO Finland
CT of torso and neck
3.7
11.5
49
134
C09AA02
ATC
enalapril; systemic
1.4
11.5
647
4919
KWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in urological surgery
9.6
11.2
22
23
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
9.6
11.2
22
23
G04CA02
ATC
tamsulosin; oral
1.3
11.2
869
6957
N99.0
ICD-10 Finland
Postprocedural renal failure
17.1
11.2
17
10
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
11.1
508
3713
E83.50
ICD-10 Finland
Hypercalcemia
3.5
11.1
51
149
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
6.4
11.1
28
44
JMA10
NOMESCO Finland
Transabdominal total splenectomy
6.1
11.0
29
48
D41
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of urinary organs
43.4
10.9
13
*
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
3.8
10.8
44
116
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.5
10.8
37
83
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
10.8
279
1792
WX892
NOMESCO Finland
Monitored bed care
1.7
10.8
228
1389
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
2.5
10.7
82
331
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
10.7
804
6396
KKB10
NOMESCO Finland
Excision of retroperitoneal tumour
17.9
10.7
16
9
L04AA06
ATC
mycophenolic acid; systemic
3.1
10.6
57
188
B03XA01
ATC
erythropoietin; parenteral
3.8
10.5
43
114
M49.5*C79.5
ICD-10 Finland
Metastatic fracture of vertebra
9.2
10.5
21
23
M10.9
ICD-10 Finland
Gout, unspecified
1.7
10.4
221
1347
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
2.6
10.3
74
292
WW200
SPAT
NA
0.5
10.2
74
1481
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
3.6
10.2
45
128
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
7.5
10.2
23
31
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
10.1
283
1857
NK6AN
NOMESCO Finland
Total body bone isotope imaging
2.2
10.1
98
448
JLC10
NOMESCO Finland
Distal pancreatectomy
8.4
10.0
21
25
B05DB
ATC
Hypertonic solutions
5.0
10.0
31
63
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
3.0
10.0
57
193
E89.6
ICD-10 Finland
Postprocedural adrenocortical(-medullary) hypofunction
40.2
10.0
12
*
JAH00
NOMESCO Finland
Laparotomy
2.4
9.9
84
361
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.0
9.9
118
589
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
7.6
9.9
22
29
C79.0
ICD-10 Finland
Secondary malignant neoplasm of kidney and renal pelvis
20.1
9.8
14
7
A04AA01
ATC
ondansetron; systemic, rectal
1.8
9.7
174
1008
B02AA02
ATC
tranexamic acid; systemic
1.6
9.7
269
1759
Z3231
NOMESCO Finland
Registered nurse
1.3
9.6
753
6018
C09BA02
ATC
enalapril and diuretics; systemic
1.6
9.6
277
1830
WX882
NOMESCO Finland
High dependency care
2.2
9.5
93
429
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.4
9.5
457
3367
KB1DG
NOMESCO Finland
Very extensive MRI of urinary tract
100.3
9.4
10
*
C68.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of urinary organs
30.1
9.4
12
*
PHN70
NOMESCO Finland
Plastic repair of inferior vena cava
+∞
9.4
9
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
9.3
899
7399
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
2.7
9.2
60
224
PG1PT
NOMESCO Finland
Extensive endovascular embolisation for bleeding with radiological guidance not elsewhere classified
5.0
9.2
28
56
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.9
9.2
140
770
TK820
NOMESCO Finland
Peritoneal dialysis
5.5
9.2
26
48
WF004
NOMESCO Finland
Palliative radiotherapy
2.4
9.2
73
305
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
5.9
9.0
24
41
N02AA01
ATC
morphine; systemic, rectal
2.9
9.0
52
179
N18
ICD-10 Finland
Chronic kidney disease
3.1
8.9
46
148
N03AX16
ATC
pregabalin; oral
1.3
8.9
598
4658
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
7.4
8.9
20
27
Q60.0
ICD-10 Finland
Renal agenesis, unilateral
24.1
8.9
12
5
105
Kela drug reimbursment
Adrenal cortical hypofunction
10.7
8.8
16
15
N19
ICD-10 Finland
Unspecified kidney failure
2.0
8.8
116
605
JN1AD
NOMESCO Finland
CT examination of upper part of abdomen
5.9
8.7
23
39
H03AA01
ATC
levothyroxine sodium; systemic
1.4
8.6
523
4007
A79
ICPC
Malignancy NOS
3.0
8.6
47
158
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.5
1164
9989
Z80.8
ICD-10 Finland
Family history of malignant neoplasm of other organs or systems
10.0
8.5
16
16
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
2.3
8.5
74
324
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
2.5
8.4
62
249
Z80.5
ICD-10 Finland
Family history of malignant neoplasm of urinary tract
90.3
8.4
9
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
4.7
8.4
27
58
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
1.9
8.4
125
682
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
8.4
140
793
XX9XW
NOMESCO Finland
NA
4.2
8.4
30
72
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
12.8
8.4
14
11
1891X
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Renal pelvis[NEOPLASMA MALIGNUM PELVIS RENIS,EI HIST VAHV]
+∞
8.3
8
*
Q85.82
ICD-10 Finland
of Hipple-Lindau syndrome
+∞
8.3
8
*
9680/3-C64.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of kidney, NOS
+∞
8.3
8
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.5
8.3
267
1811
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
8.2
852
7051
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
3.1
8.2
43
141
OAB42
NOMESCO Finland
Guidance related to known health problem
5.4
8.1
23
43
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
4.7
8.1
26
56
A10AE04
ATC
insulin glargine; parenteral
1.5
8.1
263
1788
GDA20
NOMESCO Finland
Excision of lesion of lung
10.0
8.0
15
15
N05CF01
ATC
zopiclone; oral
1.3
8.0
887
7405
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
2.3
8.0
68
295
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
8.0
197
1255
Y83.6
ICD-10 Finland
Removal of other organ (partial) (total) as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
7.2
7.9
18
25
H02AB06
ATC
prednisolone; systemic
1.2
7.9
1253
10913
C07AB07
ATC
bisoprolol; oral
1.2
7.9
1452
12857
ZXE00
NOMESCO Finland
One hour or less
1.3
7.9
1003
8512
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.1
7.9
85
409
R33
ICD-10 Finland
Retention of urine
1.5
7.9
272
1874
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
7.8
7.9
17
22
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
3.0
7.7
42
142
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
1.8
7.7
118
654
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
3.8
7.6
30
79
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.9
7.6
113
618
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
7.6
76
355
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
18.4
7.6
11
6
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
4.9
7.6
23
47
KAB00
NOMESCO Finland
Biopsy of kidney or pelvis of kidney
25.0
7.6
10
*
A04AA02
ATC
granisetron; systemic, transdermal
1.7
7.5
152
918
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
7.5
290
2048
J01CA04
ATC
amoxicillin; systemic
1.2
7.4
2086
19288
7121
FHL
Removal of local change or renal resection (eg cyst)
80.2
7.4
8
*
PC5NT
NOMESCO Finland
Endovascular embolisation for kidney bleeding with radiological guidance
80.2
7.4
8
*
UJF32
NOMESCO Finland
Coloscopy
1.3
7.4
707
5777
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.5
7.4
245
1673
NA049
NOMESCO Finland
Radiotherapy of methastasis in spine
13.4
7.4
12
9
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.0
7.3
94
487
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
2.6
7.3
49
190
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
6.2
7.2
18
29
E03.2
ICD-10 Finland
Hypothyroidism due to medicaments and other exogenous substances
7.3
7.2
16
22
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.7
7.1
29
79
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
7.1
1175
10242
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
7.1
381
2853
Z2446
NOMESCO Finland
Social worker
1.7
7.1
146
887
J01EA01
ATC
trimethoprim; systemic
1.3
7.1
582
4658
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
3.0
7.0
37
123
SPAT1254
SPAT
Administration of medicine
1.4
7.0
389
2931
A06AH03
ATC
naloxegol; oral
3.0
7.0
38
129
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.0
7.0
81
403
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.3
7.0
485
3791
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
2.8
7.0
41
146
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
5.2
6.9
20
39
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
1.8
6.9
111
626
P01AB01
ATC
metronidazole; oral, rectal
1.2
6.9
906
7695
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.8
6.9
105
581
GDA21
NOMESCO Finland
Thoracoscopic excision of lesion of lung
13.8
6.9
11
8
C09CA01
ATC
losartan; oral
1.3
6.9
680
5580
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
3.8
6.8
27
72
N05BA04
ATC
oxazepam; oral
1.3
6.8
572
4590
XF600
NOMESCO Finland
Bloodpressure measurement
1.6
6.8
174
1118
PC5SC
NOMESCO Finland
Selective angiography of kidney artery with X-ray
6.7
6.8
16
24
N28.9
ICD-10 Finland
Disorder of kidney and ureter, unspecified
6.7
6.8
16
24
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
3.4
6.7
30
89
A41.9
ICD-10 Finland
Sepsis, unspecified
1.8
6.7
107
601
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
2.9
6.6
38
132
212
Kela drug reimbursment
Gout
2.0
6.6
74
366
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
7.8
6.6
14
18
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
4.2
6.6
23
55
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
3.4
6.6
29
85
AA049
NOMESCO Finland
Radiotherapy of metasthasis in the brain
12.3
6.6
11
9
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.5
6.6
200
1340
JAH01
NOMESCO Finland
Laparoscopy
2.0
6.5
82
425
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
6.5
342
2556
E66.8
ICD-10 Finland
Other obesity
1.9
6.5
92
498
GDB10
NOMESCO Finland
Wedge resection of lung
6.2
6.5
16
26
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
6.4
130
788
2230A
ICD-9 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
70.0
6.4
7
*
1XC17
NOMESCO Finland
NA
70.0
6.4
7
*
D30.1
ICD-10 Finland
Benign neoplasm: Renal pelvis
70.0
6.4
7
*
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
8.1
6.3
13
16
C03AA03
ATC
hydrochlorothiazide; oral
1.4
6.3
273
1973
TK810
NOMESCO Finland
Hemofiltration
3.7
6.3
25
68
C68
ICD-10 Finland
Malignant neoplasm of other and unspecified urinary organs
+∞
6.2
6
*
1899X
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Urinary organ, site unspecified[NEOPLASMA MAL ORG URIN NUD,EI HIST VAHV]
+∞
6.2
6
*
8316/3-C64.9
ICD-O-3
Cyst-associated renal cell carcinoma of kidney, NOS
+∞
6.2
6
*
8318/3-C64.9
ICD-O-3
Renal cell carcinoma, sarcomatoid of kidney, NOS
+∞
6.2
6
*
8890/3-C64.9
ICD-O-3
Leiomyosarcoma, NOS, of kidney, NOS
+∞
6.2
6
*
KAD10
NOMESCO Finland
Heminephrectomy
+∞
6.2
6
*
KAC96
NOMESCO Finland
Other nephrectomy
+∞
6.2
6
*
1890C
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,MUU/TARK MÄÄR SYÖPÄ]
+∞
6.2
6
*
H02AB09
ATC
hydrocortisone; systemic
2.2
6.2
60
280
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.3
6.2
690
5736
TKC20
NOMESCO Finland
Catheterisation of bladder
1.5
6.2
216
1494
R04.2
ICD-10 Finland
Haemoptysis
1.8
6.2
99
560
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
4.0
6.1
22
55

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_KIDNEY_NOTRENALPELVIS – Malignant neoplasm of kidney, except renal pelvis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).