This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_RENAL_CELL_CARCINOMA_EXALLC for full statistics.
Renal cell carcinoma of kidney
C3_RENAL_CELL_CARCINOMA
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
1265 |
4. Check minimum number of eventsNone |
1265 |
5. Include endpointsNone |
1265 |
6. Filter based on genotype QC (FinnGen only) |
1265 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF8
Similar endpoints
↥List of similar endpoints to
Renal cell carcinoma of kidney
based on the number of shared cases.
Similar with more cases:
- Renal cell carcinoma of kidney, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of kidney, except renal pelvis
- Malignant neoplasm of urinary organs
- Malignant neoplasm of kidney, except renal pelvis, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of urinary organs, excluding all cancers (controls excluding all cancers)
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1265 | 474 | 791 |
| Unadjusted period prevalence (%) | 0.28 | 0.16 | 0.35 |
| Median age at first event (years) | 63.23 | 60.73 | 64.72 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1178
- Matched controls
- 11774
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
172.2
323.0
334
27
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
687.5
323.0
1021
108
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
323.0
1013
*
KAC10
NOMESCO Finland
Total nephrectomy with capsule
243.8
323.0
413
26
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
80.0
323.0
574
138
8317/3-C64.9
ICD-O-3
Renal cell carcinoma, chromophobe type of kidney, NOS
+∞
161.2
151
*
7125
FHL
Nephrectomy (extrrafascial)
1580.2
146.0
139
*
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
70.3
129.7
148
24
197
Kela drug reimbursment
Sunitinib
141.3
109.2
115
9
1890B
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,ADENOCARCINOMA]
1101.7
104.9
101
*
L01XE04
ATC
[U] sunitinib; oral
230.1
103.3
105
5
KAC00
NOMESCO Finland
Nephrectomy
80.5
98.2
110
15
130
Kela drug reimbursment
Malignant tumour
5.9
98.2
310
667
C64.80
ICD-10 Finland
Wilms tumour
126.5
97.7
104
9
KAD00
NOMESCO Finland
Partial nephrectomy
72.6
93.3
106
16
180
Kela drug reimbursment
Interferon alfa
73.6
83.8
95
14
KAD01
NOMESCO Finland
Percutaneous endoscopic partial nephrectomy
54.9
69.2
82
16
JN4AD
NOMESCO Finland
Body CT examination
4.8
57.6
212
515
U75
ICPC
Malignant neoplasm of kidney
84.6
57.6
64
8
1890X
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,EI HIST VAHV]
+∞
53.5
51
*
C648
ICD-10 Finland
NA
+∞
52.5
50
*
1502
Kela drug reimbursment
Cabozantinib
80.8
48.3
54
7
3012
Kela drug reimbursment
Cabozantinib
79.3
47.3
53
7
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
14.0
45.5
79
60
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
44.2
256
910
322
Kela drug reimbursment
Sunitinib
122.2
44.1
47
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
20.5
44.0
66
34
JN4BD
NOMESCO Finland
Extensive body CT
3.4
42.5
237
817
159
Kela drug reimbursment
Pazopanib
59.7
39.5
46
8
158
Kela drug reimbursment
Everolimus
201.4
38.0
39
*
JN4CD
NOMESCO Finland
Very extensive body CT
5.0
35.1
118
255
L01XE26
ATC
[U] cabozantinib; oral
185.4
34.9
36
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
5.8
33.8
99
182
B01AB10
ATC
tinzaparin; parenteral
3.9
32.4
144
408
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.5
32.3
166
531
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
8.8
32.1
70
84
N02AX02
ATC
tramadol; systemic, rectal
2.1
31.6
585
3778
L01XE11
ATC
[U] pazopanib; oral
52.9
30.5
36
7
L03AA04
ATC
NA
49.9
28.5
34
7
KA1AE
NOMESCO Finland
Kidney ultrasound examination
6.7
27.4
71
111
D30.0
ICD-10 Finland
Benign neoplasm: Kidney
13.1
27.3
48
38
18900
ICD-8 Finland
Malignant neoplasm of other and unspecified urinary organs, Kidney, except pelvis
+∞
26.1
25
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.8
24.3
70
126
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.7
24.0
110
319
2395A
ICD-9 Finland
Neoplasm of unspecified nature, Other genito-urinary organs
34.1
23.4
30
9
L01EX07
ATC
cabozantinib; oral
45.9
22.4
27
6
L03AB05
ATC
interferon alfa-2b; parenteral
24.4
22.2
31
13
A03FA01
ATC
metoclopramide; systemic, rectal
2.1
21.5
288
1569
KA3LT
NOMESCO Finland
Njurlesion coagulation
44.2
21.5
26
6
A11CC03
ATC
alfacalcidol; systemic
5.5
21.3
64
122
168
Kela drug reimbursment
Axitinib
112.0
20.6
22
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.0
20.1
82
215
L03AB04
ATC
interferon alfa-2a; parenteral
29.5
19.7
26
9
L01XE10
ATC
[U] everolimus; oral
106.8
19.6
21
*
198
Kela drug reimbursment
Sorafenib
34.9
18.9
24
7
A12AA04
ATC
calcium carbonate; oral
6.7
17.3
44
68
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
17.1
330
2040
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.1
16.7
53
108
340
Kela drug reimbursment
Everolimus
+∞
16.7
16
*
1890A
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Kidney, except pelvis[NEOPL MAL RENIS PELVI EXCEPTO,NEPHROBLASTOMA]
+∞
16.7
16
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
3.8
16.7
72
199
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.9
16.5
104
380
TK800
NOMESCO Finland
Hemodialysis
5.3
16.2
49
95
B01AB05
ATC
enoxaparin; parenteral
1.7
15.7
392
2619
N18.8
ICD-10 Finland
Other chronic renal failure
3.7
15.6
68
190
Z49.0
ICD-10 Finland
Preparatory care for dialysis
8.9
15.3
32
37
N02AA05
ATC
oxycodone; systemic
1.9
15.2
235
1337
M04AA01
ATC
allopurinol; systemic
2.0
15.0
226
1269
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
8.4
14.8
32
39
L01XE17
ATC
[U] axitinib; oral
81.1
14.6
16
*
R31
ICD-10 Finland
Unspecified haematuria
2.1
14.5
188
995
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
4.6
14.3
49
109
U14
ICPC
Kidney symptom/complaint
6.1
13.8
37
62
L01XE05
ATC
[U] sorafenib; oral
28.7
13.0
17
6
343
Kela drug reimbursment
Pazopanib
50.6
12.9
15
*
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
12.8
192
1074
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
4.2
12.7
47
114
205
Kela drug reimbursment
Chronic hypertension
1.6
12.5
441
3197
PHE70
NOMESCO Finland
Thrombectomy of inferior vena cava
+∞
12.5
12
*
N18.0
ICD-10 Finland
End-stage renal disease
5.9
12.4
34
59
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.2
363
2514
L02AB02
ATC
medroxyprogesterone; systemic (progestogens)
11.2
12.0
22
20
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
11.8
155
822
C08CA01
ATC
amlodipine; oral
1.6
11.7
475
3553
361
Kela drug reimbursment
Axitinib
65.6
11.6
13
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
11.6
109
497
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.7
11.5
32
57
R50.9
ICD-10 Finland
Fever, unspecified
2.0
11.3
164
901
V03AE01
ATC
polystyrene sulfonate; oral
5.0
11.2
35
72
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
11.2
535
4142
137
Kela drug reimbursment
Uraemia requiring dialysis
8.1
11.1
24
30
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.0
10.9
140
732
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.5
10.9
85
352
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.9
10.6
43
114
L01EX01
ATC
sunitinib; oral
60.5
10.6
12
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
10.4
94
421
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
10.3
420
3116
WZC30
NOMESCO Finland
Teaching
1.9
10.2
154
858
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
6.2
10.0
26
43
7124
FHL
Nephrectomy (simple
40.4
10.0
12
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
5.7
9.8
27
48
C03CA01
ATC
furosemide; systemic
1.5
9.8
458
3498
C65
ICD-10 Finland
Malignant neoplasm of renal pelvis
7.4
9.7
22
30
Z90.5
ICD-10 Finland
Acquired absence of kidney
55.4
9.7
11
*
UKC02
NOMESCO Finland
Cystoscopy
1.6
9.4
252
1683
KAC01
NOMESCO Finland
Percutaneous endoscopic nephrectomy
21.9
9.4
13
6
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
5.8
9.2
25
44
V03AE02
ATC
sevelamer; oral
11.6
9.1
16
14
B02AA02
ATC
tranexamic acid; systemic
1.9
9.0
130
714
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
8.8
324
2329
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
5.7
8.8
24
43
KA4AT
NOMESCO Finland
Cytology of kidney with ultrasound guidance
50.3
8.7
10
*
B05DA
ATC
Isotonic solutions
8.3
8.6
18
22
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
7.0
8.6
20
29
BCA30
NOMESCO Finland
Unilateral adrenalectomy
27.7
8.5
11
*
SPAT1153
SPAT
Removal of sutures
1.5
8.4
362
2696
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
5.9
8.3
22
38
B03XA02
ATC
darbepoetin alfa; parenteral
3.6
8.3
35
98
RD211
NOMESCO Finland
NA
2.7
8.1
53
202
AA049
NOMESCO Finland
Radiotherapy of metasthasis in the brain
33.6
8.1
10
*
NA049
NOMESCO Finland
Radiotherapy of methastasis in spine
33.6
8.1
10
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
10.1
8.0
15
15
GD1AD
NOMESCO Finland
Thorax CT examination
2.5
8.0
59
240
N02AA01
ATC
morphine; systemic, rectal
3.6
7.7
33
94
J01MA02
ATC
ciprofloxacin; systemic
1.4
7.7
457
3616
H02AB02
ATC
dexamethasone; systemic
1.9
7.6
115
644
KAC20
NOMESCO Finland
Nephroureterectomy
11.9
7.6
13
11
M907, C6488
ICD-10 Finland
NA
80.5
7.4
8
*
C02AC05
ATC
moxonidine; oral
2.2
7.4
71
329
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.3
7.3
63
277
D41.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Renal pelvis
6.9
7.3
17
25
Z51.5
ICD-10 Finland
Palliative care
2.0
7.3
91
475
Z31.5
ICD-10 Finland
Genetic counselling
3.1
7.1
37
123
TK820
NOMESCO Finland
Peritoneal dialysis
12.1
7.1
12
10
Z49.2
ICD-10 Finland
Other dialysis
6.7
6.8
16
24
GDA20
NOMESCO Finland
Excision of lesion of lung
40.3
6.8
8
*
JLC10
NOMESCO Finland
Distal pancreatectomy
16.8
6.7
10
6
Z85.5
ICD-10 Finland
Personal history of malignant neoplasm of urinary tract
16.8
6.7
10
6
KWD00
NOMESCO Finland
Reoperation for superficial haemorrhage in urological surgery
16.8
6.7
10
6
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.5
6.7
50
205
B05DB
ATC
Hypertonic solutions
7.9
6.6
14
18
M05BA02
ATC
clodronic acid; systemic
5.9
6.6
17
29
E83.50
ICD-10 Finland
Hypercalcemia
4.4
6.5
22
51
2230A
ICD-9 Finland
Benign neoplasm of kidney and other urinary organs, Kidney, except pelvis
70.2
6.4
7
*
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
6.0
6.3
16
27
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
11.1
6.3
11
10
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
9.3
6.3
12
13
8318/3-C64.9
ICD-O-3
Renal cell carcinoma, sarcomatoid of kidney, NOS
+∞
6.3
6
*
8316/3-C64.9
ICD-O-3
Cyst-associated renal cell carcinoma of kidney, NOS
+∞
6.3
6
*
1891X
ICD-9 Finland
Malignant neoplasm of kidney and other and unspecified urinary organs, Renal pelvis[NEOPLASMA MALIGNUM PELVIS RENIS,EI HIST VAHV]
+∞
6.3
6
*
7121
FHL
Removal of local change or renal resection (eg cyst)
+∞
6.3
6
*
C08CA13
ATC
lercanidipine; oral
1.6
6.2
161
1054
C68.9
ICD-10 Finland
Malignant neoplasm: Urinary organ, unspecified
26.8
6.2
8
*
B03XA01
ATC
erythropoietin; parenteral
4.5
6.2
20
45
C79.7
ICD-10 Finland
Secondary malignant neoplasm of adrenal gland
12.6
6.1
10
8
C07AB02
ATC
metoprolol; systemic
1.4
6.1
288
2166
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
3.2
6.0
29
92
M05BX04
ATC
denosumab; parenteral
2.1
6.0
67
335
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
5.2
6.0
17
33
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_RENAL_CELL_CARCINOMA – Renal cell carcinoma of kidney
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).