obesity: A disorder involving an excessive amount of body fat.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
340 |
4. Check minimum number of eventsNone |
340 |
5. Include endpointsNone |
340 |
6. Filter based on genotype QC (FinnGen only) |
326 |
Control definitions (FinnGen only)
- Control exclude
- E4_OBESITY
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E66
- Name in latin
- Obesitas medicamento provocata
Similar endpoints
↥List of similar endpoints to
Drug-induced obesity
based on the number of shared cases.
Similar with more cases:
- Obesity
- Obesity and other hyperalimentation
- Other nutritional deficiencies
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1947 | 1310 | 630 |
| Only index persons | 1879 | 1276 | 603 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.04 | 0.02 |
| Only index persons | 0.04 | 0.05 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 43.29 | 41.92 | 45.89 |
| Only index persons | 42.39 | 41.22 | 44.86 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 326 | 248 | 78 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.04 |
| Median age at first event (years) | 46.55 | 44.03 | 54.56 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 340
- Matched controls
- 3400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E66.1
ICD-10 Finland
Drug-induced obesity
+∞
307.7
340
*
E66.01
ICD-10 Finland
Obesity due to excess calories
125.6
307.7
238
62
E66.8
ICD-10 Finland
Other obesity
207.9
281.5
137
11
E66.00
ICD-10 Finland
Metabolic syndrome
55.3
163.4
96
24
E66.9
ICD-10 Finland
Obesity, unspecified
234.9
101.6
100
6
T82
ICPC
Obesity
21.2
92.0
74
44
A10BA02
ATC
metformin; oral
7.6
78.0
171
399
E66
ICD-10 Finland
Obesity
14.3
73.1
73
64
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
+∞
63.6
59
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
12.6
58.5
62
59
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
6.1
53.7
126
300
G47.3
ICD-10 Finland
Sleep apnoea
5.7
52.8
142
381
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
12.3
48.2
51
48
E11
ICD-10 Finland
Type 2 diabetes mellitus
6.3
45.2
93
193
103
Kela drug reimbursment
Diabetes, insulin-treated
5.1
45.0
131
370
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
7.5
44.1
72
118
T90
ICPC
Diabetes non-insulin dependent
5.3
43.9
119
316
N05AX12
ATC
aripiprazole; systemic
9.1
42.6
57
74
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
12.2
41.7
44
41
215
Kela drug reimbursment
Diabetes, non-insulin-treated
4.9
41.3
124
356
A10BJ06
ATC
semaglutide; parenteral
12.5
36.9
38
34
QBJ30
NOMESCO Finland
Correction of abdominal apron
372.5
34.6
34
*
C03CA01
ATC
furosemide; systemic
4.4
33.6
114
353
B01AB05
ATC
enoxaparin; parenteral
3.8
32.3
154
604
N05AH03
ATC
olanzapine; systemic
5.9
30.0
60
119
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
4.6
29.6
84
225
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.7
28.8
138
536
SPAT1262
SPAT
Handing over of treatment supplies
4.4
28.2
86
243
E66.0
ICD-10 Finland
Obesity due to excess calories
305.3
28.2
28
*
A46
ICD-10 Finland
Erysipelas
4.8
28.1
75
191
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
+∞
27.5
26
*
310
Kela drug reimbursment
Orlistat, sibutramine and other major and expensive medicines used to treat obesity
105.4
27.1
29
*
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
3.7
25.8
107
374
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.0
25.6
91
286
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.7
25.2
67
169
N06AB04
ATC
citalopram; systemic
3.5
25.1
117
441
N05AH04
ATC
quetiapine; oral
3.5
24.9
114
424
N05AA02
ATC
levomepromazine; systemic
7.4
24.3
37
55
N06AX16
ATC
venlafaxine; oral
3.6
22.6
95
332
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
5.5
22.5
47
96
205
Kela drug reimbursment
Chronic hypertension
3.6
22.5
92
316
N02AX02
ATC
tramadol; systemic, rectal
3.0
22.0
178
912
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
21.8
176
899
RD210, ,
NOMESCO Finland
18.1
21.4
33
20
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.0
21.0
140
642
SPAT1229
SPAT
Assessment of need for aid
5.6
20.8
42
83
F20.9
ICD-10 Finland
Schizophrenia, unspecified
9.0
20.4
26
31
B03BA03
ATC
hydroxocobalamin; parenteral
6.4
20.1
35
60
N03AX16
ATC
[U] pregabalin
3.1
19.6
110
455
R5140
NOMESCO Finland
Monitoring the use of the aid
4.3
19.3
56
150
N03AX09
ATC
lamotrigine; oral
5.1
19.3
44
97
I10
ICD-10 Finland
Essential (primary) hypertension
2.8
19.2
197
1121
JDF01
NOMESCO Finland
Laparoscopic gastroplasty
+∞
18.9
18
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
3.8
18.8
66
203
A10BB12
ATC
glimepiride; oral
6.2
18.4
33
58
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
6.8
18.3
30
48
Z3229
NOMESCO Finland
Other healthcare associate professional
4.4
17.8
49
126
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
3.9
17.2
56
163
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.7
17.0
61
190
WX722
NOMESCO Finland
PEEP
7.7
16.7
24
33
A10AE04
ATC
insulin glargine; parenteral
4.1
16.7
50
137
F31.8
ICD-10 Finland
Other bipolar affective disorders
7.2
16.4
25
37
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
6.6
16.2
27
44
N05BA01
ATC
diazepam; systemic, rectal
3.3
16.1
70
246
N06AB03
ATC
fluoxetine; oral
3.3
16.0
69
241
N05AB03
ATC
perphenazine; systemic, rectal
6.3
16.0
28
48
A10BK03
ATC
empagliflozin; oral
4.1
15.9
48
132
N05CD07
ATC
temazepam; oral
3.9
15.8
51
147
Z3226
NOMESCO Finland
Physiotherapist
2.9
15.8
92
383
A08AB01
ATC
orlistat; oral
+∞
15.7
15
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
3.5
15.7
60
194
N05BA06
ATC
lorazepam; systemic, sublingual
4.8
15.6
37
84
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.5
15.6
40
97
Z3231
NOMESCO Finland
Registered nurse
2.6
15.5
125
615
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.9
15.4
50
145
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.7
15.2
37
86
N05AX08
ATC
risperidone; systemic
4.1
15.2
45
122
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.7
15.1
103
465
TLC00
NOMESCO Finland
Insertion of intrauterine device
3.8
14.6
48
140
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.2
14.6
31
64
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
11.6
14.3
26
24
Z2446
NOMESCO Finland
Social worker
3.9
14.0
44
124
J01FF01
ATC
clindamycin; systemic
2.6
14.0
115
566
A10BH01
ATC
sitagliptin; oral
4.2
13.9
39
101
B81
ICPC
Anaemia vit B12/folate deficiency
6.6
13.9
23
37
R4190
NOMESCO Finland
Nutritional therapy
5.5
13.9
28
55
B01AA03
ATC
warfarin; systemic
3.4
13.8
55
182
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.1
13.8
41
111
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
6.8
13.8
22
34
N06AX05
ATC
trazodone; oral
5.9
13.6
25
45
SPAT1301
SPAT
No procedures
2.5
13.5
127
664
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.4
13.5
53
174
H03AA01
ATC
levothyroxine sodium; systemic
2.5
13.4
111
548
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.0
12.9
39
107
M79.6
ICD-10 Finland
Pain in limb
2.3
12.8
172
1045
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
12.8
179
1107
N02BF02
ATC
pregabalin; oral
4.2
12.7
36
94
S97
ICPC
Chronic ulcer skin
4.6
12.5
31
73
N03AG01
ATC
valproic acid; systemic, rectal
3.9
12.1
38
107
N05AN01
ATC
lithium; oral
6.0
12.1
22
39
A02BC02
ATC
pantoprazole; systemic
2.4
12.1
241
1714
I50.9
ICD-10 Finland
Heart failure, unspecified
3.8
11.9
39
113
ZXE20
NOMESCO Finland
More than three and less than five hours
3.0
11.9
60
228
A10AC01
ATC
insulin (human); parenteral
3.7
11.9
40
118
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.1
11.8
55
200
N02BE01
ATC
paracetamol; systemic, rectal
4.9
11.8
322
2667
L28
ICPC
Limited function/disability (L)
2.9
11.8
65
260
XG466
NOMESCO Finland
Sleep oxymetry
10.6
11.7
22
22
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
10.6
11.7
22
22
EBA05
NOMESCO Finland
Complicated extraction of tooth
2.5
11.7
95
461
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.4
11.7
46
151
N05BA04
ATC
oxazepam; oral
2.3
11.7
115
608
SPAT1310
SPAT
Counselling related to known health issue
2.3
11.7
134
756
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
4.8
11.6
27
60
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.6
11.6
81
365
A06AD11
ATC
lactulose; oral
3.2
11.6
51
179
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
11.6
49
168
P06
ICPC
Sleep disturbance
2.8
11.6
64
256
L15
ICPC
Knee symptom/complaint
2.4
11.5
102
514
M79.7
ICD-10 Finland
Fibromyalgia
4.7
11.4
27
61
M54.5
ICD-10 Finland
Low back pain
2.2
11.4
146
860
IGY02
NOMESCO Finland
Psychiatric monitoring contact
5.0
11.4
25
53
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.4
11.3
29
70
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
11.3
155
937
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
4.5
11.2
28
66
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.6
11.2
77
344
M54.4
ICD-10 Finland
Lumbago with sciatica
2.6
11.2
81
371
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
11.2
81
371
F61.0
ICD-10 Finland
Mixed personality disorders
9.7
11.2
22
24
C07AB07
ATC
bisoprolol; oral
2.2
11.1
153
925
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
4.4
11.1
29
71
160
Kela drug reimbursment
exenatide
14.5
11.1
18
13
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
3.0
11.0
53
196
A28
ICPC
Limited function/disability NOS
3.0
11.0
54
202
J45
ICD-10 Finland
Asthma
3.1
11.0
51
185
R4140
NOMESCO Finland
Psychotherapy
18.6
10.8
16
9
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
3.0
10.8
53
198
A08AA10
ATC
sibutramine; oral
62.0
10.7
12
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.5
10.6
38
117
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.8
10.6
59
237
RD112, ,
NOMESCO Finland
113.4
10.5
11
*
L17
ICPC
Foot/toe symptom/complaint
2.2
10.5
115
632
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.6
10.5
36
108
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
5.4
10.4
21
41
SPAT1307
SPAT
Psychosocial counselling and guidance
3.5
10.4
38
119
A10BJ05
ATC
dulaglutide; parenteral
13.7
10.3
17
13
WX110
NOMESCO Finland
Infiltration anesthesia
2.4
10.3
269
2071
N05AF03
ATC
chlorprothixene; systemic
5.5
10.2
20
38
S89.9
ICD-10 Finland
Unspecified injury of lower leg
4.7
10.2
24
54
A10BH05
ATC
linagliptin; oral
5.3
10.2
21
42
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
2.2
10.2
112
615
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.7
10.2
34
100
TPH07
NOMESCO Finland
Cathetrisation of artery
3.3
10.2
40
131
A10BK01
ATC
dapagliflozin; oral
4.2
10.0
27
68
B01AB04
ATC
dalteparin; parenteral
4.6
10.0
24
55
J01DB01
ATC
cefalexin; oral
3.0
9.9
301
2456
SPAT1249
SPAT
Treatment-related counselling outside office
2.1
9.9
155
974
ZY010
NOMESCO Finland
Hospital outpatient
3.7
9.9
32
92
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.7
9.9
32
92
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.1
9.9
45
161
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.0
9.9
46
167
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.9
9.7
50
192
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.8
9.7
22
48
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
7.5
9.7
22
31
R03AC02
ATC
salbutamol; inhalant
2.1
9.6
219
1572
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
10.5
9.6
18
18
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
10.5
9.6
18
18
J01MA02
ATC
ciprofloxacin; systemic
2.1
9.6
131
779
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
9.6
81
396
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
9.6
134
805
N05CF01
ATC
zopiclone; oral
2.1
9.5
121
700
SPAT1305
SPAT
Counselling and guidance related to physical exercise
3.0
9.5
44
159
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
5.4
9.5
19
37
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
4.7
9.4
22
49
A10BD07
ATC
metformin and sitagliptin; systemic
5.1
9.4
20
41
2780A
ICD-9 Finland
Obesity and other hyperalimentation, Obesity
+∞
9.4
9
*
M04AA01
ATC
allopurinol; systemic
3.2
9.4
39
132
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.9
9.3
48
184
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.1
9.3
121
705
N06AX03
ATC
mianserin; oral
4.1
9.3
26
67
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.7
9.3
56
233
EBA00
NOMESCO Finland
Extraction of tooth
2.1
9.3
139
853
L03
ICPC
Low back symptom/complaint
2.1
9.3
114
650
P99
ICPC
Psychological disorders other
4.5
9.3
23
54
N02AJ06
ATC
codeine and paracetamol; systemic
2.0
9.3
164
1070
N03AX12
ATC
[U] gabapentin; oral
2.4
9.2
71
333
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
9.2
55
228
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.2
9.2
105
582
K02.1
ICD-10 Finland
Caries of dentine
2.1
9.2
230
1698
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.5
9.1
32
97
A10BX04
ATC
[U] exenatide
37.8
9.1
11
*
UJF32
NOMESCO Finland
Coloscopy
2.2
9.0
89
465
R60.0
ICD-10 Finland
Localized oedema
2.9
9.0
45
170
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
9.0
50
200
N03AX11
ATC
topiramate; oral
4.7
9.0
21
47
R06.5
ICD-10 Finland
Mouth breathing
3.1
8.9
38
131
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.4
8.7
67
313
J01MA12
ATC
levofloxacin; systemic
2.4
8.7
67
313
ZXD10
NOMESCO Finland
Scheduled procedure
2.0
8.7
138
861
ZXD05
NOMESCO Finland
Urgent procedure
2.0
8.6
125
755
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
8.5
41
151
WX290
NOMESCO Finland
Other blockage of nerve
2.0
8.5
191
1340
A10BJ01
ATC
exenatide; parenteral
28.3
8.5
11
*
OAB72
NOMESCO Finland
Weight control and weight loss guidance
28.3
8.5
11
*
Z50.4
ICD-10 Finland
Psychotherapy, not elsewhere classified
20.7
8.5
12
6
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
8.5
99
550
SPAT1254
SPAT
Administration of medicine
2.6
8.5
52
218
N05AH02
ATC
clozapine; systemic
7.0
8.5
20
30
N04AA02
ATC
biperiden; systemic
8.2
8.5
18
23
K07
ICPC
Swollen ankles/oedema
5.1
8.5
18
37
Z2445
NOMESCO Finland
Psychologist
3.7
8.4
27
77
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
8.4
51
213
A08
ICPC
Swelling
4.0
8.4
24
63
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
9.8
8.4
16
17
N06AX21
ATC
duloxetine; oral
2.5
8.3
56
246
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.1
8.3
23
59
A08AA02
ATC
fenfluramine; oral
15.0
8.3
13
9
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
8.2
126
773
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.4
8.1
60
275
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
17.7
8.1
12
7
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.1
8.1
36
127
K04.5
ICD-10 Finland
Chronic apical periodontitis
2.1
8.0
98
553
N06AB10
ATC
escitalopram; oral
2.1
8.0
99
561
A10BJ02
ATC
liraglutide; parenteral
6.9
8.0
19
29
C03AA03
ATC
hydrochlorothiazide; oral
3.2
8.0
32
106
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.7
8.0
44
175
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.2
7.9
21
52
F31
ICD-10 Finland
Bipolar affective disorder
8.8
7.9
16
19
C09AA05
ATC
ramipril; oral
2.3
7.9
69
341
P29
ICPC
Psychological sympt/compl other
2.8
7.9
40
152
OAB72, ,
SPAT
11.2
7.9
14
13
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.1
7.8
22
57
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.2
7.8
31
102
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
7.7
181
1275
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
7.7
60
282
SFA10
NOMESCO Finland
One-surface restoration
1.9
7.7
209
1544
R50.9
ICD-10 Finland
Fever, unspecified
2.4
7.6
60
283
K04.08
ICD-10 Finland
Other specified pulpit
2.8
7.6
41
161
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.0
7.6
35
126
M54.8
ICD-10 Finland
Other dorsalgia
3.5
7.5
26
78
C10AA01
ATC
simvastatin; oral
2.0
7.5
106
629
N06AB06
ATC
sertraline; oral
2.4
7.5
59
278
SPAT1008
SPAT
Photography of fundus of the eye or interpretation of photograph
6.2
7.5
19
32
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.5
7.4
50
220
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
9.7
7.4
14
15
SPAT1312
SPAT
General health counselling
1.9
7.3
122
765
RD140, ,
NOMESCO Finland
+∞
7.3
7
*
IAB12
NOMESCO Finland
Psychiatric psychosis consultation
+∞
7.3
7
*
SGC10
NOMESCO Finland
Pulp capping
2.6
7.3
45
189
IGY99
NOMESCO Finland
Other psychiatric treatment contact
4.5
7.3
18
42
N05BA12
ATC
alprazolam; oral
2.6
7.3
44
183
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.4
7.3
27
85
SGA01
NOMESCO Finland
Emergency treatment
2.2
7.3
73
381
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.9
7.2
21
56
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.6
7.1
42
173
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
7.1
106
640
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.0
7.1
20
52
J01DA09
ATC
[U] cefadroxil
2.0
7.1
102
608
A10AB05
ATC
insulin aspart; parenteral
3.0
7.1
32
114
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.9
7.1
137
901
C03DA01
ATC
spironolactone; oral
2.7
7.1
39
155
N05AD01
ATC
haloperidol; systemic
6.1
7.0
18
31
SPAT1263
SPAT
Sampling
1.8
7.0
151
1026
N05AA01
ATC
chlorpromazine; systemic, rectal
8.5
6.9
14
17
T81.9
ICD-10 Finland
Unspecified complication of procedure
8.5
6.9
14
17
Z71.8
ICD-10 Finland
Other specified counselling
1.9
6.9
126
812
S18
ICPC
Laceration/cut
1.8
6.9
153
1049
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.6
6.9
42
176
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
11.3
6.8
12
11
R60.9
ICD-10 Finland
Oedema, unspecified
3.7
6.8
22
63
N02BF01
ATC
gabapentin; oral
2.8
6.8
34
128
A10BD20
ATC
metformin and empagliflozin; oral
17.1
6.8
10
6
H02AB06
ATC
prednisolone; systemic
1.8
6.8
158
1097
J45.1
ICD-10 Finland
Nonallergic asthma
2.9
6.8
32
117
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
2.5
6.7
44
190
C08CA01
ATC
amlodipine; oral
1.9
6.7
104
633
SPAT1234
SPAT
Support of social functional capacity
3.9
6.7
20
54
C09BA02
ATC
enalapril and diuretics; systemic
3.3
6.7
25
79
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
23.0
6.7
9
*
E28.2
ICD-10 Finland
Polycystic ovarian syndrome
6.1
6.7
17
29
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
6.7
27
90
F32
ICD-10 Finland
Depressive episode
3.0
6.7
29
101
N06AA09
ATC
amitriptyline; systemic
2.6
6.7
40
166
M48.0
ICD-10 Finland
Spinal stenosis
2.6
6.6
39
160
188
Kela drug reimbursment
Psychosis requiring demanding treatment
12.6
6.6
11
9
S80.0
ICD-10 Finland
Contusion of knee
2.8
6.6
34
130
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.8
6.6
35
136
R06.0
ICD-10 Finland
Dyspnoea
2.0
6.6
90
525
N05AE04
ATC
ziprasidone; systemic
10.3
6.6
12
12
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.8
6.6
20
55
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.3
6.6
55
266
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
6.4
6.5
16
26
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
6.4
6.5
16
26
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
6.5
149
1024
A02BC05
ATC
esomeprazole; systemic
1.8
6.5
140
945
K04.0
ICD-10 Finland
Pulpitis
2.4
6.5
47
213
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
71.1
6.4
7
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
6.4
73
398
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.4
6.4
47
214
R10.0
ICD-10 Finland
Acute abdomen
4.2
6.4
17
42
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
4.2
6.4
17
42
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
3.1
6.4
27
92
A10AE05
ATC
insulin detemir; parenteral
3.3
6.4
24
76
J20
ICD-10 Finland
Acute bronchitis
2.4
6.4
45
201
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
6.4
72
391
N06AX11
ATC
mirtazapine; oral
1.8
6.4
125
818
H02AB07
ATC
prednisone; oral
2.4
6.4
48
221
JKA20
NOMESCO Finland
Cholecystectomy
6.8
6.4
15
23
R03AC12
ATC
salmeterol; inhalant
3.6
6.4
21
61
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
11.3
6.3
11
10
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.1
6.3
27
93
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.4
6.3
47
216
R04
ICPC
Breathing problem other
3.8
6.3
19
52
ACC51
NOMESCO Finland
Release of median nerve
2.8
6.3
32
122
IEY08
NOMESCO Finland
Psychiatric coaching, domestic and community skills
27.2
6.3
8
*
A10BX01
ATC
guar gum; oral
5.5
6.2
17
32
N91.1
ICD-10 Finland
Secondary amenorrhoea
6.5
6.2
15
24
SPAT1240
SPAT
Therapeutic discussion
2.2
6.2
53
258
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
6.2
81
464
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
6.2
75
419
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.9
6.2
18
48
M54
ICD-10 Finland
Dorsalgia
2.3
6.2
52
252
S10
ICPC
Boil/carbuncle
3.1
6.1
26
89
M15
ICD-10 Finland
Polyarthrosis
3.6
6.1
20
58
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
6.9
6.1
14
21
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
6.1
196
1480
Z02.7
ICD-10 Finland
Issue of medical certificate
2.7
6.1
32
124
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.2
6.1
15
25
R03DA04
ATC
theophylline; systemic, rectal
4.0
6.1
17
44
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
4.0
6.1
17
44
S06
ICPC
Rash localized
3.2
6.0
24
79
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
6.0
91
548
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
3.8
6.0
18
49
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
112
370
4.02
29.83
2.4
1.6
1239.58
1279.10
nmol/l
0.17
93
275
201
1003
3.46
27.82
5.8
4.9
34.87
36.50
g/l
4.08
190
950
88
263
4.17
26.67
6.4
7.2
1.03
1.06
mmol/l
0.52
81
240
183
929
3.10
23.39
2.7
1.7
90.70
96.26
pmol/l
1.00
122
456
140
612
3.19
23.24
3.9
3.7
10.16
11.30
mg/mmol
0.08
86
373
136
609
3.06
21.32
2.8
2.0
3.23
2.98
mg/l
0.48
119
524
148
698
2.98
21.09
3.3
3.2
8.30
7.45
mmol/l
1.02
113
603
207
1187
2.90
20.20
9.2
6.6
1.22
1.22
mmol/l
0.07
186
1030
122
528
3.04
20.13
1.7
1.4
19.74
21.38
nmol/l
0.64
105
454
200
1136
2.85
19.71
3.4
2.2
67.44
76.79
nmol/l
5.23
189
1026
192
1080
2.79
19.08
8.2
5.8
1.21
1.22
mmol/l
1.22
180
993
231
1482
2.74
16.86
6.8
4.5
6.63
6.39
mmol/l
1.00
219
1344
151
806
2.57
15.90
2.7
2.4
119.06
58.40
u/l
0.39
141
751
176
1023
2.49
15.28
16.9
9.7
1.20
1.14
inr
0.40
43
313
84
342
2.93
14.96
3.2
2.4
2.57
2.37
g/l
1.95
73
323
102
475
2.64
13.94
2.5
1.5
414.82
12165903.34
pmol/l
0.50
89
411
313
2487
4.26
13.53
9.2
4.5
40.98
38.26
mmol/mol
5.38
302
2349
276
2060
2.81
12.92
8.3
6.9
83.45
75.29
u/l
2.18
259
1937
84
374
2.65
12.42
3.3
2.4
11.93
14.36
umol/l
2.45
78
350
57
217
2.95
11.27
2.3
2.4
0.20
0.23
g/l
1.59
52
202
291
2289
2.88
11.22
5.8
4.2
14.38
14.50
pmol/l
0.38
274
2103
73
318
2.65
11.19
3.5
2.5
20.31
24.01
%
1.10
61
277
149
890
2.20
11.17
3.2
3.0
30.33
29.98
u/l
0.05
139
852
204
1380
2.20
11.13
4.3
2.8
94.70
85.27
ug/l
0.25
188
1293
143
850
2.18
10.76
3.1
3.4
2.33
2.36
mmol/l
1.42
125
760
117
649
2.22
10.40
2.2
2.6
353.11
7830.61
umol/l
3.27
88
578
198
1352
2.11
10.19
5.2
5.9
10.18
10.11
umol/l
0.04
188
1276
101
534
2.27
10.04
3.2
3.1
1219.45
853.12
ng/l
0.66
79
436
317
2683
3.68
9.39
6.1
3.8
6.31
5.68
mmol/l
8.98
297
2482
220
1626
2.00
8.39
13.7
9.1
4.30
3.92
e9/l
1.67
192
1412
15
15
10.40
8.11
2.8
3.3
45.86
11.29
mu/l
1.16
15
15
55
245
2.49
7.93
11.5
6.8
104.36
104.09
mmol/l
0.14
55
245
17
23
7.72
7.77
18.8
19.8
1672.47
1499.57
nmol/l
0.21
17
23
311
2667
2.95
7.71
4.6
3.5
1.55
1.20
mmol/l
10.78
288
2485
20
50
4.19
7.45
1.3
1.2
—
—
—
0
0
50
220
2.49
7.38
10.9
9.2
1.64
1.07
mmol/l
0.44
42
176
311
2695
2.81
7.01
7.1
4.8
1.79
1.80
mu/l
0.05
295
2498
78
432
2.05
6.61
3.1
2.6
2.44
2.43
mmol/l
0.33
67
374
247
1992
1.88
6.21
4.2
2.8
56.12
38.02
u/l
1.43
236
1880
317
2809
2.90
6.16
5.8
4.2
2.71
2.85
mmol/l
2.23
298
2634
180
1326
1.76
6.11
3.0
2.5
—
—
—
0
0
313
2760
2.69
6.07
5.1
3.8
1.30
1.54
mmol/l
23.75
291
2590
314
2776
2.71
6.00
5.2
3.9
4.42
4.79
mmol/l
9.77
296
2614
69
378
2.04
5.99
2.2
1.7
1.39
1.40
%
0.06
59
341
132
894
1.78
5.96
3.7
3.2
478.54
28.59
ng/l
0.48
89
526
14
23
6.30
5.75
16.4
9.3
0.52
0.65
mmol/l
1.93
14
23
36
154
2.50
5.63
1.9
1.5
—
—
—
0
0
64
349
2.03
5.61
2.3
1.8
—
—
—
0
0
40
181
2.37
5.55
4.8
4.7
2.51
1.73
mmol/l
0.56
35
149
101
645
1.81
5.48
2.8
2.2
—
—
—
0
0
32
131
2.59
5.47
13.9
8.1
0.74
0.69
%
0.16
32
131
98
625
1.80
5.33
1.7
1.7
1.22
0.89
mg/l
0.97
74
454
20
66
3.16
5.03
4.8
1.6
—
—
—
0
0
29
119
2.57
4.94
8.4
5.5
25.64
24.92
mmol/l
0.42
29
119
26
101
2.70
4.93
1.7
1.5
—
—
—
0
0
31
132
2.48
4.90
14.4
8.1
1.23
1.39
%
0.49
31
132
10
13
7.89
4.88
1.1
2.1
—
—
—
0
0
10
13
7.89
4.88
1.1
2.1
—
—
—
0
0
8
7
11.66
4.81
1.6
1.9
17.29
21.57
umol/l
—
8
7
30
128
2.47
4.73
14.8
8.3
93.52
94.45
%
0.67
30
128
37
174
2.26
4.71
4.3
4.4
86.85
79.67
ng/l
0.15
31
158
127
906
1.64
4.47
3.1
3.0
—
—
—
0
0
175
1354
1.60
4.40
6.2
6.0
28.60
29.07
%
0.24
159
1280
38
190
2.13
4.18
3.6
3.9
4.43
4.56
pmol/l
0.32
33
167
173
1347
1.58
4.15
6.1
5.8
57.36
56.70
%
0.33
158
1271
249
2116
1.66
4.11
4.7
3.7
15.06
9.64
mm/h
6.28
231
1968
8
10
8.16
4.08
1.0
2.3
—
—
—
0
0
8
10
8.16
4.08
1.0
2.3
—
—
—
0
0
327
3037
3.01
4.04
13.4
9.2
30.67
24.75
u/l
4.66
321
2939
44
236
1.99
4.02
3.7
2.0
29.68
33.00
u/l
0.24
34
201
18
65
2.87
3.92
1.7
1.4
—
—
—
0
0
50
289
1.86
3.67
5.2
3.7
28.51
33.18
%
3.84
37
191
297
2676
1.87
3.66
18.3
10.0
91.22
88.19
ml/min/173m2
1.40
244
2136
21
86
2.54
3.62
2.0
1.7
—
—
—
0
0
7
9
7.91
3.57
1.0
1.6
—
—
—
0
0
7
9
7.91
3.57
1.0
1.6
—
—
—
0
0
33
168
2.07
3.48
2.1
2.6
3.87
5.31
ug/l
0.63
26
150
314
2892
2.12
3.47
22.2
11.4
21.70
20.91
mg/l
0.18
289
2169
9
18
5.10
3.39
1.0
1.2
—
—
—
0
0
21
89
2.45
3.39
2.2
2.0
—
—
—
0
0
7
10
7.12
3.38
1.0
2.3
—
—
—
0
0
10
23
4.45
3.33
1.1
2.0
—
—
—
0
0
10
23
4.45
3.33
1.1
2.0
—
—
—
0
0
10
23
4.45
3.33
1.1
2.0
—
—
—
0
0
61
387
1.70
3.27
2.7
2.8
5.55
2.96
e6/l
0.74
34
194
105
769
1.53
3.12
1.4
1.3
0.73
1.16
u/ml
0.85
36
212
41
237
1.83
3.02
2.2
1.7
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
9
22
4.17
2.90
1.0
1.2
—
—
—
0
0
27
137
2.05
2.89
2.4
1.4
—
—
—
0
0
6
9
6.76
2.88
1.0
1.6
—
—
—
0
0
6
9
6.76
2.88
1.0
1.6
—
—
—
0
0
62
409
1.63
2.87
3.0
3.3
57.81
175.53
ng/l
1.39
42
276
13
47
2.84
2.85
1.1
1.8
—
—
—
0
0
13
47
2.84
2.85
1.1
1.8
—
—
—
0
0
17
73
2.40
2.69
7.9
3.8
3.82
3.88
mmol/l
0.20
17
73
39
231
1.78
2.66
2.3
1.6
—
—
—
0
0
49
310
1.68
2.66
7.6
6.4
—
—
—
0
0
169
1394
1.42
2.63
4.1
3.4
0.00
0.00
estimate
0.50
26
296
94
695
1.49
2.62
1.6
1.6
1.71
1.35
mmol/l
1.99
80
603
96
715
1.48
2.58
3.2
2.8
0.27
0.35
e6/l
0.28
76
521
6
11
5.53
2.55
1.0
1.3
—
—
—
0
0
6
11
5.53
2.55
1.0
1.4
—
—
—
0
0
13
51
2.61
2.47
2.5
2.1
—
—
—
0
0
34
198
1.80
2.46
3.2
2.2
6165.54
5200.30
u/l
0.06
11
89
10
33
3.09
2.37
1.1
1.8
—
—
—
0
0
38
232
1.72
2.36
5.2
2.6
—
—
—
0
0
98
746
1.44
2.33
4.5
3.7
0.00
0.00
estimate
0.50
26
278
46
299
1.62
2.26
2.8
2.7
6.01
5.93
umol/l
0.02
35
252
9
29
3.16
2.24
1.1
1.8
—
—
—
0
0
166
1395
1.37
2.19
5.5
4.6
0.00
0.00
estimate
0.50
27
283
60
423
1.51
2.09
2.6
2.6
0.58
0.86
e6/l
0.91
33
228
5
10
5.06
2.08
1.0
1.2
—
—
—
0
0
5
10
5.06
2.08
1.0
1.2
—
—
—
0
0
17
83
2.10
2.05
1.1
1.7
503.18
415.41
mg/l
0.37
17
78
166
1413
1.34
1.94
4.1
3.4
0.00
0.01
estimate
0.50
26
279
5
12
4.21
1.83
1.0
1.0
—
—
—
0
0
9
35
2.61
1.81
1.8
1.4
—
—
—
0
0
19
325
0.56
1.69
1.1
1.6
—
—
—
0
0
5
14
3.61
1.62
1.0
1.7
—
—
—
0
0
10
43
2.36
1.60
1.2
1.4
—
—
—
0
0
6
20
3.03
1.59
1.2
1.1
—
—
—
0
0
5
15
3.37
1.53
3.0
4.1
—
—
—
0
0
5
15
3.37
1.53
1.2
1.3
—
—
—
0
0
12
59
2.07
1.45
2.3
1.7
—
—
—
0
0
0
38
0.00
1.35
0.0
1.7
—
13.12
—
0
38
18
292
0.59
1.34
1.3
1.5
—
—
—
0
0
14
76
1.88
1.32
1.1
1.3
272.00
339.50
ug/g
—
7
43
8
34
2.38
1.30
1.9
1.4
—
—
—
0
0
8
34
2.38
1.30
1.9
1.4
—
—
—
0
0
22
138
1.64
1.30
1.9
1.6
—
—
—
0
0
11
55
2.03
1.28
1.3
6.9
—
262.83
iu/ml
—
0
12
8
35
2.32
1.27
1.0
1.1
—
—
—
0
0
8
35
2.32
1.27
1.9
1.4
—
—
—
0
0
8
35
2.32
1.27
1.9
1.4
—
—
—
0
0
8
35
2.32
1.27
1.9
1.4
—
—
—
0
0
8
39
2.08
1.16
3.0
1.8
—
—
—
0
0
14
80
1.78
1.14
1.1
1.4
—
—
—
0
0
13
73
1.81
1.12
1.1
1.9
11.71
10.18
mg/l
0.39
13
67
7
138
0.50
1.12
1.3
1.5
—
—
—
0
0
89
744
1.27
1.09
1.5
1.6
—
—
—
0
0
126
1097
1.24
1.08
4.7
3.4
—
—
—
0
0
7
33
2.14
1.06
1.0
1.2
—
—
—
0
0
9
47
1.94
1.03
1.3
1.3
—
—
—
0
0
9
47
1.94
1.03
1.2
4.2
—
877.00
—
0
5
9
47
1.94
1.03
1.3
1.3
—
—
—
0
0
28
198
1.45
1.01
2.1
2.2
71.45
74.68
ml/min/173m2
0.14
11
79
26
363
0.69
1.01
5.7
4.2
17.83
21.34
%
—
10
173
68
558
1.27
0.97
1.4
1.3
18.96
29.54
iu/ml
1.03
19
183
8
43
1.88
0.88
1.1
1.3
—
—
—
0
0
19
272
0.68
0.85
2.7
2.8
0.59
0.74
ug/l
0.59
14
170
10
58
1.75
0.80
2.6
1.7
—
—
—
0
0
13
82
1.61
0.79
1.2
1.1
—
—
—
0
0
5
27
1.86
0.68
3.2
2.4
105.60
106.15
mmol/l
—
5
27
5
27
1.86
0.68
1.6
1.3
—
—
—
0
0
5
27
1.86
0.68
1.0
1.2
—
—
—
0
0
65
554
1.21
0.68
1.3
1.2
2.11
9.56
u/ml
3.00
25
225
22
162
1.38
0.68
1.4
1.4
—
—
—
0
0
5
28
1.80
0.66
1.2
1.4
—
—
—
0
0
330
3247
1.55
0.64
35.3
17.0
263.81
257.57
e9/l
0.97
324
3180
13
87
1.51
0.64
1.5
2.0
2.01
5.95
iu/l
—
8
29
330
3248
1.54
0.62
35.6
17.0
40.34
40.17
%
0.25
318
3103
21
277
0.74
0.62
1.7
1.6
—
—
—
0
0
14
97
1.46
0.60
1.0
1.1
—
—
—
0
0
14
97
1.46
0.60
1.0
1.1
—
—
—
0
0
330
3250
1.52
0.59
35.2
17.0
4.53
4.49
e12/l
1.02
323
3177
12
172
0.69
0.57
1.3
1.5
—
—
—
0
0
28
350
0.78
0.57
1.9
1.7
—
—
—
0
0
11
160
0.68
0.57
1.2
1.4
—
—
—
0
0
11
160
0.68
0.57
1.2
1.4
—
—
—
0
0
6
36
1.68
0.57
2.0
2.0
—
—
—
0
0
6
37
1.63
0.56
1.0
1.1
—
—
—
0
0
11
159
0.68
0.55
1.2
1.4
—
—
—
0
0
11
159
0.68
0.55
1.2
1.4
—
—
—
0
0
23
179
1.31
0.53
1.0
1.0
—
—
—
0
0
15
109
1.39
0.52
1.5
2.0
—
—
—
0
0
33
271
1.24
0.51
1.2
1.2
221.20
159.21
iu/ml
—
10
120
65
574
1.16
0.48
2.4
2.1
—
—
—
0
0
12
85
1.43
0.47
1.5
1.6
—
256.00
—
0
5
7
51
1.38
0.44
1.7
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
178.52
—
0
15
11
79
1.41
0.41
1.4
1.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
14
180
0.77
0.38
1.4
1.5
—
—
—
0
0
8
115
0.69
0.37
1.9
1.6
—
—
—
0
0
58
519
1.14
0.37
2.3
2.0
—
—
—
0
0
7
52
1.35
0.31
1.4
2.3
—
—
—
0
0
7
53
1.33
0.31
4.0
2.4
—
—
—
0
0
7
55
1.28
0.30
1.3
1.2
—
—
—
0
0
224
2178
1.08
0.27
3.7
3.6
—
—
—
0
0
41
455
0.89
0.26
4.0
4.5
1.49
2.65
ug/l
0.88
33
399
5
72
0.69
0.26
1.2
1.4
—
—
—
0
0
27
236
1.16
0.25
4.4
3.9
3.70
27.15
ug/l
0.71
21
195
6
81
0.74
0.24
1.5
1.2
—
—
—
0
0
5
39
1.29
0.23
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
4.0
—
—
—
0
0
0
11
0.00
0.21
0.0
4.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
24.95
—
0
12
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
5
43
1.17
0.21
3.6
3.4
58.80
56.98
%
—
5
43
5
43
1.17
0.21
1.2
1.1
—
—
—
0
0
6
49
1.23
0.20
1.2
1.0
—
—
—
0
0
10
121
0.82
0.18
2.0
1.7
—
—
—
0
0
13
148
0.87
0.12
1.5
1.5
—
—
—
0
0
13
115
1.14
0.10
3.0
1.9
—
—
—
0
0
5
45
1.11
0.10
4.0
1.5
—
—
—
0
0
6
55
1.09
0.09
1.3
4.1
—
3.15
—
0
8
13
143
0.91
0.07
1.8
1.3
236.75
256.84
miu/ml
—
7
70
7
81
0.86
0.07
1.1
1.4
—
—
—
0
0
13
118
1.11
0.07
1.2
1.4
1.41
1.16
g/l
2.01
13
112
9
103
0.87
0.06
1.7
1.3
—
—
—
0
0
70
717
0.97
0.05
1.6
1.5
—
—
—
0
0
21
198
1.06
0.05
1.3
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
8.43
—
0
7
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
41.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
23.66
—
0
9
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
65.67
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint E4_OBESITYDRUG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_OBESITYDRUG | 2.566 [2.01, 3.27] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.542 |
During the follow-up period (1.1.1998 — 31.12.2019), 125 out of 1189 females with E4_OBESITYDRUG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_OBESITYDRUG | 3.083 [2.32, 4.1] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.065 |
During the follow-up period (1.1.1998 — 31.12.2019), 123 out of 581 males with E4_OBESITYDRUG died.
Mortality risk
Mortality risk for people of age
years, who have E4_OBESITYDRUG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.326% | 0.507% |
| 5 | 1.67% | 3.295% |
| 10 | 4.356% | 8.667% |
| 15 | 8.38% | 15.952% |
| 20 | 13.586% | 26.563% |
Relationships between endpoints
↥Index endpoint: E4_OBESITYDRUG – Drug-induced obesity
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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