dermatomyositis: Dermatomyositis (DM) is a type of idiopathic inflammatory myopathy characterized by evocative skin lesions and symmetrical proximal muscle weakness.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
181 |
4. Check minimum number of eventsNone |
181 |
5. Include endpointsNone |
181 |
6. Filter based on genotype QC (FinnGen only) |
181 |
Control definitions (FinnGen only)
- Control exclude
- M13_SYSTCONNECT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M33
- Name in latin
- Dermato[poly]myositis non specificata
Similar endpoints
↥List of similar endpoints to
Dermatopolymyositis, unspecified
based on the number of shared cases.
Similar with more cases:
- Dermatopolymyositis (FG)
- Dermatopolymyositis
- Systemic connective tissue disorders
- Autoimmune diseases related-to ILD
- Finngen Rheumatological endpoints
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 919 | 568 | 346 |
| Only index persons | 811 | 503 | 308 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.02 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 59.15 | 58.28 | 60.73 |
| Only index persons | 57.73 | 56.78 | 59.29 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 181 | 105 | 76 |
| Unadjusted period prevalence (%) | 0.03 | 0.04 | 0.03 |
| Median age at first event (years) | 56.65 | 52.96 | 61.74 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 170
- Matched controls
- 1697
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
+∞
239.7
168
*
M33.1
ICD-10 Finland
Other dermatomyositis
+∞
74.6
66
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
22.4
60.3
97
95
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
11.1
44.6
121
309
M33.2
ICD-10 Finland
Polymyositis
+∞
43.6
40
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
14.3
41.0
77
93
H02AB06
ATC
prednisolone; systemic
11.5
40.2
144
551
L04AX01
ATC
azathioprine; systemic
36.7
39.2
50
19
P01BA02
ATC
hydroxychloroquine; oral
16.0
37.6
65
63
M60.9
ICD-10 Finland
Myositis, unspecified
378.8
32.0
31
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
29.0
27
*
M05BA04
ATC
alendronic acid; oral
14.1
27.1
48
46
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
13.1
25.7
47
48
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
+∞
25.7
24
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
12.4
25.5
48
52
G72.9
ICD-10 Finland
Myopathy, unspecified
97.2
23.4
25
*
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
251.0
22.1
22
*
NXL00
NOMESCO Finland
Biopsy of muscle
+∞
21.3
20
*
L04AA06
ATC
mycophenolic acid; systemic
48.5
21.1
25
6
J99.1*M33.9
ICD-10 Finland
Respiratory disorders in dermatopolymyositis
+∞
20.2
19
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
13.1
19.6
35
33
M60.8
ICD-10 Finland
Other myositis
+∞
17.0
16
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.3
14.6
41
81
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
14.2
104
519
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
+∞
12.7
12
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
6.6
12.5
33
60
L04AD01
ATC
ciclosporin; systemic
19.9
12.3
18
10
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
+∞
11.6
11
*
M05BA07
ATC
risedronic acid; oral
18.7
11.5
17
10
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.2
11.0
73
320
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
12.4
10.9
19
17
XA402
NOMESCO Finland
ENMG
17.5
10.6
16
10
M33.0
ICD-10 Finland
Juvenile dermatomyositis
+∞
10.5
10
*
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
10.5
10
*
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
+∞
10.5
10
*
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
10.5
10
*
H02AB07
ATC
prednisone; oral
4.1
10.2
43
130
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
15.9
10.2
16
11
L04AA01
ATC
[U] ciclosporin; systemic
21.6
10.0
14
7
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
7.7
9.7
22
32
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.2
9.1
55
218
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
9.1
38
114
A02BC02
ATC
pantoprazole; systemic
2.9
9.0
125
838
ZX120
NOMESCO Finland
Intravenous
4.5
8.8
32
84
M33
ICD-10 Finland
Dermatopolymyositis
+∞
8.4
8
*
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
+∞
8.4
8
*
JN4BD
NOMESCO Finland
Extensive body CT
4.1
8.3
33
94
XG410
NOMESCO Finland
Flow-volume spirometry
6.3
8.1
21
37
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
6.5
8.0
20
34
R50.9
ICD-10 Finland
Fever, unspecified
3.6
7.7
36
118
R13
ICD-10 Finland
Dysphagia
5.8
7.7
21
40
1XC02
NOMESCO Finland
NA
83.6
7.5
8
*
D07AB08
ATC
desonide; topical
3.6
7.2
33
107
M05BB03
ATC
alendronic acid and colecalciferol; oral
17.6
6.8
10
6
D07AC01
ATC
betamethasone; topical
2.5
6.8
71
384
M79.0
ICD-10 Finland
Rheumatism, unspecified
9.3
6.7
13
15
L99
ICPC
Musculoskeletal disease other
13.0
6.7
11
9
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
13.0
6.7
11
9
R06.0
ICD-10 Finland
Dyspnoea
2.6
6.6
55
263
N03AX16
ATC
pregabalin; oral
2.7
6.5
48
213
E0000UV
ATC
NA
2.3
6.5
76
435
L88
ICPC
Rheumatoid/seropositive arthritis
6.4
6.5
16
27
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.6
6.4
29
93
NJ3DG
NOMESCO Finland
Very extensive MRI examination of extremities with high intensity magnet
+∞
6.3
6
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
6.1
44
193
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
7.7
6.0
13
18
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
64
6
163.27
63.78
4.0
1.3
6.6
5.5
u/l
—
59
6
58
5
169.02
57.80
1.4
1.0
—
—
—
0
0
145
434
12.77
55.30
13.5
1.9
196.8
183.7
u/l
0.16
145
406
50
38
17.80
55.10
2.6
1.4
—
—
—
0
0
45
40
14.64
44.92
1.9
1.1
0.2
0.3
g/l
1.86
45
40
45
43
13.60
42.86
1.9
1.0
1.1
1.3
g/l
2.33
45
43
35
38
11.18
30.17
1.7
1.4
366.8
0.1
iu/ml
—
9
8
152
870
5.66
19.20
19.5
9.6
4.2
4.0
e9/l
0.66
147
763
16
10
17.45
18.73
1.6
1.1
—
—
—
0
0
16
10
17.45
18.73
1.6
1.1
—
—
—
0
0
16
11
15.86
17.84
1.6
1.1
—
—
—
0
0
16
11
15.86
17.84
1.6
1.1
—
—
—
0
0
16
11
15.86
17.84
1.6
1.1
—
—
—
0
0
18
21
9.41
14.38
4.6
2.7
61.6
64.0
%
0.25
18
21
17
20
9.28
13.47
4.3
1.8
4.4
6.0
e9/l
1.07
17
20
122
714
3.17
12.18
5.2
3.4
0.0
0.0
estimate
0.00
34
137
13
12
11.59
12.09
1.5
1.2
—
—
—
0
0
123
733
3.12
11.70
5.3
3.3
0.0
0.0
estimate
0.00
34
134
121
725
3.02
11.21
6.5
4.4
0.0
0.0
estimate
0.00
34
140
106
601
2.84
10.73
3.5
2.2
73.0
77.0
nmol/l
0.81
101
537
120
727
2.93
10.69
10.2
6.4
1.2
1.2
mmol/l
0.48
103
621
49
185
3.26
10.36
3.0
2.1
24.8
23.6
%
0.20
44
165
22
46
5.31
10.31
4.3
2.8
—
—
—
0
0
39
128
3.61
10.26
1.8
1.9
406.8
362.4
nmol/l
0.18
39
117
49
201
2.97
8.88
3.1
2.0
2.3
2.3
g/l
0.41
49
182
10
10
10.53
8.72
1.6
1.1
—
—
—
0
0
20
45
4.87
8.60
6.2
2.8
36.9
38.3
g/l
0.36
20
40
19
41
5.06
8.57
6.5
3.0
0.0
0.0
g/l
0.00
19
41
11
13
8.94
8.55
1.4
1.2
8.8
64.8
%
—
5
8
50
213
2.86
8.42
2.3
1.8
—
—
—
0
0
69
347
2.60
8.40
3.1
1.8
3.3
3.0
mg/l
0.55
63
300
18
39
5.01
8.07
6.8
3.1
0.0
0.0
g/l
0.00
18
39
18
39
5.01
8.07
6.8
3.1
0.0
0.0
g/l
0.00
18
39
55
252
2.70
8.02
1.5
1.2
70.5
35.8
iu/ml
0.60
14
82
20
51
4.28
7.38
6.3
2.6
3.1
2.9
g/l
0.27
20
44
15
31
5.19
7.07
1.3
1.6
—
—
—
0
0
15
31
5.19
7.07
1.7
1.2
—
—
—
0
0
75
419
2.35
7.03
5.8
3.0
866.9
1052.0
ng/l
0.44
70
353
26
84
3.45
6.91
3.2
3.3
4.9
5.1
kpa
0.89
26
77
71
393
2.33
6.75
6.3
3.8
0.0
0.0
estimate
0.00
34
135
20
55
3.96
6.68
6.3
2.5
—
—
—
0
0
20
55
3.96
6.68
6.3
2.5
3.5
3.6
g/l
0.21
20
43
20
55
3.96
6.68
6.3
2.5
7.1
7.3
g/l
0.20
20
45
9
5
18.83
6.33
1.8
1.6
—
—
—
0
0
11
21
5.51
5.60
1.2
1.1
—
—
—
0
0
34
145
2.66
5.57
1.9
1.7
—
—
—
0
0
12
26
4.87
5.34
1.7
1.7
—
—
—
0
0
12
26
4.87
5.34
1.2
1.3
—
—
—
0
0
14
35
4.25
5.27
1.6
1.7
—
—
—
0
0
10
19
5.51
5.10
1.5
1.6
—
—
—
0
0
18
56
3.46
5.04
1.6
1.6
1.2
1.6
g/l
1.94
18
48
47
244
2.25
5.01
1.2
1.2
37.7
9.0
u/ml
0.62
14
90
8
7
11.88
4.83
1.6
5.9
—
—
—
0
0
82
536
1.97
4.70
4.5
2.8
—
—
—
0
0
85
563
1.96
4.69
5.8
3.5
—
—
—
0
0
58
337
2.06
4.61
1.4
1.2
0.8
1.6
u/ml
0.68
13
92
14
40
3.71
4.43
1.2
1.1
—
—
—
0
0
32
148
2.41
4.41
2.1
1.7
—
—
—
0
0
10
22
4.75
4.36
1.5
1.6
—
—
—
0
0
13
36
3.81
4.29
1.7
1.7
—
—
—
0
0
20
74
2.91
4.25
1.7
1.7
—
—
—
0
0
48
269
2.07
4.16
1.9
1.6
1174.5
1190.0
nmol/l
0.04
40
205
10
23
4.54
4.14
1.1
1.3
3.4
15.4
u/ml
—
5
5
9
14
6.70
4.03
2.0
1.4
2.6
4.1
mg/l
—
9
14
10
24
4.35
3.94
1.2
1.3
—
—
—
0
0
11
29
3.97
3.86
1.5
1.6
—
—
—
0
0
61
383
1.89
3.79
4.2
2.8
6763.7
9651.0
umol/l
0.16
55
332
6
5
12.34
3.79
1.8
2.8
870.8
1242.0
u/ml
—
6
5
9
17
5.51
3.56
1.8
1.4
—
—
—
0
0
24
109
2.39
3.43
4.1
4.4
1.2
1.2
mmol/l
0.10
24
97
56
352
1.86
3.42
1.8
1.4
17.8
21.8
nmol/l
1.74
48
298
65
429
1.80
3.39
4.0
2.8
0.2
0.4
e6/l
1.57
53
313
73
505
1.75
3.21
2.4
3.4
2.3
2.4
mmol/l
1.58
67
440
43
253
1.92
3.20
3.5
2.6
0.8
1.0
e6/l
0.37
28
137
7
12
6.02
3.05
1.1
1.0
—
—
—
0
0
7
13
5.55
2.89
2.0
1.6
—
—
—
0
0
9
23
4.06
2.81
1.9
1.7
—
—
—
0
0
29
156
2.02
2.77
6.5
7.3
0.5
1.5
mmol/l
1.09
23
122
67
469
1.68
2.75
2.9
2.2
55.1
55.8
u/l
0.07
62
433
6
10
6.16
2.72
1.0
1.1
—
—
—
0
0
5
7
7.30
2.56
1.4
1.0
—
—
—
0
0
5
7
7.30
2.56
1.4
1.0
—
—
—
0
0
24
125
2.06
2.50
7.4
6.7
1.3
1.4
mmol/l
0.16
24
120
78
579
1.61
2.49
5.9
3.5
81.7
38.7
ng/l
0.70
72
389
38
235
1.78
2.39
3.8
2.8
5.6
2.0
e6/l
1.06
23
121
5
8
6.39
2.38
1.0
1.3
—
—
—
0
0
6
13
4.73
2.29
1.0
1.1
—
—
—
0
0
6
14
4.39
2.17
1.2
1.3
—
—
—
0
0
5
10
5.11
2.08
1.8
1.5
—
—
—
0
0
7
20
3.60
2.07
1.6
1.2
—
—
—
0
0
6
15
4.10
2.05
2.2
1.5
—
—
—
0
0
133
1480
0.62
2.04
5.2
4.4
5.7
6.0
mmol/l
2.00
126
1356
18
92
2.06
1.98
1.6
1.5
—
—
—
0
0
5
11
4.64
1.95
1.0
1.2
—
—
—
0
0
125
1401
0.65
1.83
28.7
14.0
38.9
40.1
%
0.78
87
1045
11
47
2.43
1.81
1.2
1.4
—
—
—
0
0
6
146
0.39
1.74
1.2
1.8
—
—
—
0
0
5
13
3.92
1.72
1.2
1.2
—
—
—
0
0
12
55
2.27
1.71
3.1
2.1
—
—
—
0
0
5
14
3.64
1.62
1.4
1.4
—
—
—
0
0
8
32
2.57
1.61
2.5
2.2
25.7
26.3
mmol/l
—
8
25
6
20
3.07
1.59
1.3
1.8
—
—
—
0
0
14
72
2.02
1.53
1.6
1.3
—
—
—
0
0
5
15
3.40
1.53
1.4
2.0
—
—
—
0
0
5
15
3.40
1.53
1.4
2.0
—
—
—
0
0
5
15
3.40
1.53
1.4
2.0
—
—
—
0
0
7
27
2.65
1.53
2.6
1.3
—
—
—
0
0
6
21
2.92
1.52
1.3
1.7
—
—
—
0
0
26
166
1.66
1.47
2.6
4.8
2.9
33.6
ug/l
0.66
21
141
6
23
2.66
1.38
1.3
1.3
—
—
—
0
0
6
23
2.66
1.38
1.3
1.3
—
—
—
0
0
5
17
2.99
1.37
1.0
1.1
—
3.9
—
0
6
23
147
1.65
1.31
3.4
3.5
—
—
—
0
0
10
48
2.15
1.30
2.9
1.9
—
—
—
0
0
38
278
1.46
1.21
5.8
3.5
335.7
292.9
ng/l
0.08
29
217
141
1514
0.69
1.21
5.0
4.5
4.9
4.7
mmol/l
1.16
134
1399
140
1505
0.69
1.20
5.0
4.4
1.4
1.5
mmol/l
1.20
132
1386
135
1458
0.71
1.16
4.7
4.0
1.6
1.3
mmol/l
2.81
127
1340
33
237
1.48
1.15
2.7
1.9
29.5
29.1
s
0.10
33
231
7
30
2.39
1.13
1.9
1.3
—
—
—
0
0
33
240
1.46
1.09
1.3
1.4
—
—
—
0
0
128
1158
1.36
1.07
5.2
3.9
15.0
14.7
pmol/l
0.59
122
1041
72
604
1.32
1.01
2.8
1.9
95.3
95.0
pmol/l
0.02
43
306
7
37
1.93
0.95
1.1
1.2
—
—
—
0
0
161
1524
1.51
0.94
33.2
13.0
17.7
22.9
mg/l
1.93
148
1184
6
27
2.26
0.94
1.2
1.1
—
—
—
0
0
146
1545
0.72
0.94
5.3
5.0
2.9
2.8
mmol/l
1.09
138
1426
37
284
1.38
0.92
2.1
3.0
2.5
2.5
mmol/l
0.71
32
249
14
87
1.66
0.90
15.6
5.9
25.9
24.9
mmol/l
0.54
14
87
8
44
1.86
0.87
1.1
1.2
—
—
—
0
0
8
45
1.81
0.85
1.1
1.2
—
—
—
0
0
42
337
1.32
0.79
2.1
1.7
1.4
1.2
mg/l
0.22
29
266
14
91
1.58
0.78
1.4
1.2
113.7
124.5
iu/ml
—
5
41
7
38
1.88
0.74
1.0
1.5
—
—
—
0
0
81
717
1.23
0.69
5.4
4.0
—
—
—
0
0
8
49
1.66
0.63
2.4
1.6
—
—
—
0
0
137
1443
0.79
0.62
7.1
5.5
40.6
39.9
mmol/mol
0.43
132
1345
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
6
35
1.74
0.58
3.2
1.5
—
—
—
0
0
12
83
1.48
0.53
11.4
9.7
92.0
94.2
%
0.61
12
83
33
395
0.80
0.52
3.7
4.6
22.2
21.3
%
0.16
17
206
151
1457
1.22
0.41
25.3
12.5
84.3
81.7
ml/min/173m2
0.60
134
1189
43
376
1.19
0.40
2.7
2.3
—
—
—
0
0
22
179
1.26
0.39
1.5
1.9
1.8
1.4
%
1.96
15
158
24
201
1.22
0.34
5.9
4.4
31.8
30.9
%
0.17
19
125
6
45
1.34
0.34
1.3
1.5
—
—
—
0
0
6
45
1.34
0.34
1.0
1.3
—
344.8
—
0
25
90
957
0.88
0.33
2.9
2.9
—
—
—
0
0
16
128
1.27
0.33
4.5
3.7
6.0
5.8
kpa
0.48
16
122
10
76
1.33
0.28
1.2
1.3
—
—
—
0
0
26
299
0.85
0.28
2.8
3.0
0.7
0.8
ug/l
0.37
17
205
8
65
1.24
0.27
6.1
3.6
56.5
46.8
%
—
8
65
9
73
1.24
0.26
3.7
2.3
1.8
1.2
%
—
9
73
145
1410
1.14
0.26
6.0
4.6
2.0
1.9
mu/l
0.62
137
1279
12
146
0.81
0.23
3.6
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
3.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
3.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.3
—
13.5
—
0
11
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
15
127
1.20
0.20
3.3
2.1
60.7
65.1
ml/min/173m2
—
6
54
0
14
0.00
0.20
0.0
1.0
—
444.6
—
0
9
0
14
0.00
0.20
0.0
1.1
—
42.5
—
0
8
165
1625
1.17
0.19
34.6
15.6
75.3
76.9
umol/l
0.17
165
1625
7
58
1.22
0.18
3.0
1.8
—
—
—
0
0
108
1044
1.09
0.18
4.5
2.8
73.6
46.5
u/l
1.53
103
982
8
70
1.15
0.16
3.1
2.0
—
—
—
0
0
24
265
0.89
0.16
1.7
1.5
—
—
—
0
0
156
1580
0.91
0.12
28.4
15.1
3.9
4.0
mmol/l
0.96
151
1534
156
1574
0.94
0.07
27.7
15.0
139.4
139.8
mmol/l
1.16
151
1529
12
113
1.07
0.02
4.4
2.7
4.5
4.4
kpa
0.11
12
106
17
163
1.05
0.01
3.1
1.9
—
—
—
0
0
49
489
1.00
0.00
4.8
5.0
3.3
2.9
ug/l
0.09
44
438
42
425
0.98
0.00
1.6
1.6
1.8
1.3
mmol/l
1.82
35
358
20
195
1.03
0.00
8.0
6.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.0
—
115.6
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
6
0.00
0.00
0.0
1.0
—
125.2
—
0
6
7
75
0.93
0.00
1.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
112.0
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint M13_DERMATOPOLYNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_DERMATOPOLYNAS | 2.848 [2.14, 3.79] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.207 |
During the follow-up period (1.1.1998 — 31.12.2019), 130 out of 495 females with M13_DERMATOPOLYNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_DERMATOPOLYNAS | 2.483 [1.74, 3.55] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.017 |
During the follow-up period (1.1.1998 — 31.12.2019), 87 out of 295 males with M13_DERMATOPOLYNAS died.
Mortality risk
Mortality risk for people of age
years, who have M13_DERMATOPOLYNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.296% | 0.595% |
| 5 | 1.603% | 3.498% |
| 10 | 4.077% | 7.608% |
| 15 | 7.333% | 14.038% |
| 20 | 12.719% | 22.408% |
Relationships between endpoints
↥Index endpoint: M13_DERMATOPOLYNAS – Dermatopolymyositis, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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