juvenile dermatomyositis: Juvenile dermatomyositis (JDM) is the early-onset form of dermatomyositis (DM, see this term), a systemic, autoimmune inflammatory muscle disorder, characterized by proximal muscle weakness, evocative skin lesion, and systemic manifestations.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
532 |
6. Filter based on genotype QC (FinnGen only) |
516 |
Control definitions (FinnGen only)
- Control exclude
- RHEUMA_ENDPOINTS
Extra metadata
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Dermatopolymyositis (FG)
based on the number of shared cases.
Similar with more cases:
- Dermatopolymyositis
- Systemic connective tissue disorders
- Autoimmune diseases related-to ILD
- Finngen Rheumatological endpoints
- Autoimmune diseases
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3476 | 2143 | 1288 |
| Only index persons | 2514 | 1586 | 928 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.06 | 0.04 |
| Only index persons | 0.05 | 0.06 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 59.02 | 59.14 | 58.69 |
| Only index persons | 55.63 | 55.68 | 55.54 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 516 | 321 | 195 |
| Unadjusted period prevalence (%) | 0.10 | 0.11 | 0.09 |
| Median age at first event (years) | 55.93 | 54.39 | 58.46 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 532
- Matched controls
- 5320
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P01BA02
ATC
hydroxychloroquine; oral
62.2
310.0
179
43
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
129.3
307.7
279
45
L04AX03
ATC
methotrexate; systemic
66.5
307.7
218
55
M33.2
ICD-10 Finland
Polymyositis
+∞
305.7
263
*
L04AX01
ATC
azathioprine; systemic
41.5
252.3
161
55
M33.9
ICD-10 Finland
Dermatopolymyositis, unspecified
+∞
214.5
191
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
63.5
190.4
107
21
M33.1
ICD-10 Finland
Other dermatomyositis
+∞
189.2
170
*
G72.9
ICD-10 Finland
Myopathy, unspecified
90.5
159.1
84
11
L04AA06
ATC
mycophenolic acid; systemic
58.9
134.0
76
15
H02AB06
ATC
prednisolone; systemic
9.9
122.5
428
1567
M60.9
ICD-10 Finland
Myositis, unspecified
218.2
118.9
119
7
M05BA04
ATC
alendronic acid; oral
10.0
111.6
150
201
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
7.1
109.8
354
1165
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
24.2
107.0
79
38
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
10.5
105.2
133
164
L04AD01
ATC
ciclosporin; systemic
35.9
81.7
52
16
H02AB07
ATC
prednisone; oral
6.3
76.3
159
335
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
424.3
75.8
74
*
NXL00
NOMESCO Finland
Biopsy of muscle
410.9
73.6
72
*
L01BA01
ATC
methotrexate; systemic
410.9
73.6
72
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.4
67.6
132
259
M17.1
ICD-10 Finland
Other primary gonarthrosis
9.4
65.0
84
104
NJ3BG
NOMESCO Finland
MRI examination of extremities with high intensity magnet
241.9
63.6
64
*
NJ3CG
NOMESCO Finland
Extensive MRI examination of extremities with median high magnet
684.9
63.2
61
*
L88
ICPC
Rheumatoid/seropositive arthritis
326.3
58.5
58
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
8.2
55.8
80
112
M13.9
ICD-10 Finland
Arthritis, unspecified
13.2
55.7
55
46
M60.8
ICD-10 Finland
Other myositis
199.8
53.0
54
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
46.6
326
1610
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
251.2
45.7
46
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
89.9
44.7
49
6
J99.1*M33.2
ICD-10 Finland
Respiratory disorders in polymyositis
+∞
42.3
40
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
15.1
42.0
38
27
M05BA07
ATC
risedronic acid; oral
8.9
41.3
54
67
L99
ICPC
Musculoskeletal disease other
13.6
38.7
37
29
M35.3
ICD-10 Finland
Polymyalgia rheumatica
12.4
36.4
37
32
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
10.7
34.9
39
39
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
33.9
213
942
A07EC01
ATC
sulfasalazine; oral, rectal
10.2
32.8
38
40
L04AA01
ATC
[U] ciclosporin
58.3
32.7
38
7
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
6.1
32.4
60
109
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
31.6
30
*
L28
ICPC
Limited function/disability (L)
3.5
31.2
129
441
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
+∞
30.5
29
*
ZX120
NOMESCO Finland
Intravenous
4.3
30.2
89
240
XA402
NOMESCO Finland
ENMG
9.4
27.1
33
37
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
284.7
27.0
27
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
26.2
180
817
L19
ICPC
Muscle symptom/complaint NOS
8.1
25.3
35
46
C03CA01
ATC
furosemide; systemic
2.7
24.7
200
983
TGC00
NOMESCO Finland
Bronchial lavation
7.5
24.5
36
51
N03AX16
ATC
[U] pregabalin
2.9
24.4
150
639
J99.1*M33.9
ICD-10 Finland
Respiratory disorders in dermatopolymyositis
+∞
24.1
23
*
A02BC02
ATC
pantoprazole; systemic
2.8
24.0
391
2665
TPH04
NOMESCO Finland
Cathetrisation of vein
2.8
23.8
153
666
R50.9
ICD-10 Finland
Fever, unspecified
3.2
23.8
110
398
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
23.8
102
353
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.3
23.5
65
166
G72.8
ICD-10 Finland
Other specified myopathies
8.8
23.3
30
36
XG410
NOMESCO Finland
Flow-volume spirometry
5.7
23.2
45
85
XX9XE
NOMESCO Finland
Other ultrasound examination
68.2
23.0
26
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
5.8
22.8
43
79
L04AA13
ATC
[U] leflunomide
239.9
22.8
23
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.0
22.7
70
194
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
34.0
22.6
29
9
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.8
22.6
138
583
R4110
NOMESCO Finland
Physiotherapy
2.6
22.3
181
882
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
8.0
22.3
31
41
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
65.4
22.0
25
*
NGA20
NOMESCO Finland
Exploration of soft tissue knee or lower leg, open
65.4
22.0
25
*
7104A
ICD-9 Finland
Diffuse diseases of connective tissue, Polymyositis
+∞
22.0
21
*
M33.0
ICD-10 Finland
Juvenile dermatomyositis
+∞
22.0
21
*
71610
ICD-8 Finland
Polymyositis and dermatomyositis, Polymyositis
+∞
22.0
21
*
Z3226
NOMESCO Finland
Physiotherapist
2.8
21.5
128
533
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.4
21.2
87
292
M79.0
ICD-10 Finland
Rheumatism, unspecified
7.2
21.0
32
47
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
4.4
20.9
55
135
R4120
NOMESCO Finland
Occupational therapy
4.3
20.5
57
146
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
50.1
20.3
24
5
C08CA05
ATC
nifedipine; systemic
4.3
20.0
54
135
R13
ICD-10 Finland
Dysphagia
3.9
19.8
62
173
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
19.7
85
293
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.4
19.1
39
77
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
+∞
18.9
18
*
R06.0
ICD-10 Finland
Dyspnoea
2.4
18.5
167
844
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.5
18.0
46
110
J99.1
ICD-10 Finland
Respiratory disorders in other diffuse connective tissue disorders
+∞
17.8
17
*
M33
ICD-10 Finland
Dermatopolymyositis
+∞
17.8
17
*
XPX04
NOMESCO Finland
Angioscopy
185.9
17.6
18
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.2
17.6
78
273
E0000UV, ,
ATC
2.2
17.5
244
1476
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
21.8
17.4
25
12
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.6
17.4
125
567
D07AC01
ATC
betamethasone; topical
2.2
17.3
215
1239
N02AX02
ATC
tramadol; systemic, rectal
2.2
17.2
233
1389
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.1
16.5
77
277
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.0
16.3
48
128
M16.1
ICD-10 Finland
Other primary coxarthrosis
7.0
16.3
25
37
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.7
16.2
54
157
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.3
16.2
65
214
A28
ICPC
Limited function/disability NOS
2.6
15.1
104
460
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
15.0
140
710
SPAT1229
SPAT
Assessment of need for aid
3.7
14.8
49
142
JN4BD
NOMESCO Finland
Extensive body CT
2.8
14.7
82
325
71600
ICD-8 Finland
Polymyositis and dermatomyositis, Dermatomyositis
+∞
14.6
14
*
NG4AA
NOMESCO Finland
Lower leg X-ray examination
5.6
14.6
28
52
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.5
14.5
36
84
A07AA02
ATC
nystatin; oral
3.6
14.5
50
149
UJF32
NOMESCO Finland
Coloscopy
2.2
14.1
153
823
Z50.1
ICD-10 Finland
Other physical therapy
3.9
14.1
42
113
M05BX04
ATC
denosumab; parenteral
3.6
14.1
48
142
L29
ICPC
Musculoskeletal sympt/complt other
3.3
14.0
57
189
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
5.8
14.0
26
47
NJ3DG
NOMESCO Finland
Very extensive MRI examination of extremities with high intensity magnet
+∞
13.6
13
*
7103B
ICD-9 Finland
Diffuse diseases of connective tissue, Dermatomyositis[DERMATOMYOSITIS ADULTORUM]
+∞
13.6
13
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.0
13.6
211
1299
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
13.5
154
843
TNG10
NOMESCO Finland
Puncture of knee
143.5
13.5
14
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
6.3
13.5
23
38
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.0
13.5
62
221
A02BC01
ATC
omeprazole; systemic
2.1
13.4
159
885
NF1AA
NOMESCO Finland
Hip X-ray examination
3.8
13.3
41
113
R4190
NOMESCO Finland
Nutritional therapy
4.6
13.3
32
73
B01AB05
ATC
enoxaparin; parenteral
2.1
13.2
155
857
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.1
13.2
58
201
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
29.2
13.0
17
6
B07.9
ICD-10 Finland
Verruca simplex
5.0
13.0
28
58
G71.9
ICD-10 Finland
Primary disorder of muscle, unspecified
51.3
12.9
15
*
H02AB04
ATC
methylprednisolone; systemic
2.5
12.7
88
388
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.5
12.6
31
72
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
6.4
12.6
21
34
R1250
NOMESCO Finland
Evaluation of functional capability
6.4
12.6
21
34
1XC02, ,
NOMESCO Finland
25.0
12.5
17
7
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
5.8
12.5
23
41
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
4.1
12.5
35
90
D07AB08
ATC
desonide; topical
2.7
12.3
74
305
XQ848
NOMESCO Finland
Dermatological photography
4.9
12.3
27
57
UJF30
NOMESCO Finland
Ileoscopy through colon
2.8
12.0
64
247
A02BC05
ATC
esomeprazole; systemic
1.9
12.0
221
1429
S18
ICPC
Laceration/cut
1.9
12.0
237
1569
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
11.9
76
322
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
11.9
100
481
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.1
11.8
138
759
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
66.5
11.7
13
*
M48.0
ICD-10 Finland
Spinal stenosis
2.6
11.6
70
288
M01AH01
ATC
celecoxib; oral
2.4
11.5
89
413
H05AA02
ATC
teriparatide; parenteral
35.9
11.3
14
*
M62.9
ICD-10 Finland
Disorder of muscle, unspecified
35.9
11.3
14
*
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.9
11.3
56
208
N03AX12
ATC
[U] gabapentin; oral
2.4
11.3
90
423
WX002
NOMESCO Finland
Sedation and analgesia
2.3
11.2
101
499
J05AB01
ATC
aciclovir; systemic
2.1
11.2
132
726
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
11.2
240
1620
EBA10
NOMESCO Finland
Operative extraction of tooth
2.6
11.1
68
282
N28
ICPC
Limited function/disability (N)
9.5
11.1
22
24
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
11.0
59
229
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.5
10.9
27
63
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
10.8
84
389
Z3229
NOMESCO Finland
Other healthcare associate professional
2.9
10.8
54
201
E000001, ,
ATC
2.1
10.8
114
600
H02AB09
ATC
hydrocortisone; systemic
5.1
10.8
23
47
M79.1
ICD-10 Finland
Myalgia
2.4
10.7
85
398
J01FF01
ATC
clindamycin; systemic
2.0
10.7
148
862
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
10.7
173
1063
H26.3
ICD-10 Finland
Drug-induced cataract
14.6
10.5
17
12
GD1AD
NOMESCO Finland
Thorax CT examination
3.2
10.5
44
148
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.2
10.5
44
148
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
10.5
154
914
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.0
10.5
47
165
212
Kela drug reimbursment
Gout
+∞
10.4
10
*
M60.0
ICD-10 Finland
Infective myositis
+∞
10.4
10
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
16.4
10.4
16
10
M25.5
ICD-10 Finland
Pain in joint
2.0
10.4
153
909
318
Kela drug reimbursment
Teriparatide
33.2
10.4
13
*
J01DB01
ATC
cefalexin; oral
2.1
10.4
429
3540
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
23.9
10.3
14
6
I50.9
ICD-10 Finland
Heart failure, unspecified
2.3
10.3
81
378
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.8
10.1
31
85
L90
ICPC
Osteoarthrosis of knee
4.9
10.1
22
46
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.8
10.1
23
50
M81.4
ICD-10 Finland
Drug-induced osteoporosis
40.9
10.0
12
*
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.0
10.0
28
72
N06AA09
ATC
amitriptyline; systemic
2.6
9.9
61
253
XG466
NOMESCO Finland
Sleep oxymetry
4.4
9.9
25
59
3015
Kela drug reimbursment
Alirocumab and evolocumab for the treatment of hypercholesterolaemia and dyslipidaemia
20.5
9.8
14
7
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
20.5
9.8
14
7
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
9.7
188
1216
M04AA01
ATC
allopurinol; systemic
2.5
9.5
63
271
C07AB07
ATC
bisoprolol; oral
1.8
9.5
262
1882
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
101.8
9.4
10
*
G72.4
ICD-10 Finland
Inflammatory myopathy, not elsewhere classified
+∞
9.4
9
*
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
+∞
9.4
9
*
L93.0
ICD-10 Finland
Discoid lupus erythematosus
22.2
9.4
13
6
5BA08, ,
NOMESCO Finland
22.2
9.4
13
6
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
22.2
9.4
13
6
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
9.3
201
1342
J01DA01
ATC
[U] cefalexin
1.8
9.3
324
2485
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
9.2
90
458
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.8
9.2
49
189
A02BC03
ATC
lansoprazole; oral
1.9
9.2
159
991
M05BA06
ATC
ibandronic acid; systemic
4.9
9.1
20
42
R4110, ,
SPAT
2.7
9.1
50
196
A41.9
ICD-10 Finland
Sepsis, unspecified
4.2
9.1
24
59
M13.0
ICD-10 Finland
Polyarthritis, unspecified
37.4
9.0
11
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
9.0
72
337
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.7
8.9
28
78
SPAT1231
SPAT
Assessment of adjustments needed in living environment
8.2
8.9
19
24
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.6
8.9
21
47
WZA10
NOMESCO Finland
Extensive medical or dental certificate
11.0
8.8
16
15
M79.7
ICD-10 Finland
Fibromyalgia
7.4
8.8
20
28
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
50.8
8.7
10
*
WX892
NOMESCO Finland
Monitored bed care
2.7
8.7
49
195
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.9
8.7
42
154
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
8.6
58
252
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
28.0
8.5
11
*
NG1DA
NOMESCO Finland
X-ray of knees
28.0
8.5
11
*
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
28.0
8.5
11
*
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
8.5
189
1265
294
Kela drug reimbursment
Alirocumab and evolocumab for the treatment of hypercholesterolaemia and dyslipidaemia
20.4
8.5
12
6
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
8.5
99
539
C08CA01
ATC
amlodipine; oral
1.7
8.4
203
1389
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
91.5
8.4
9
*
G71.08
ICD-10 Finland
Other muscular dystrophy
91.5
8.4
9
*
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
91.5
8.4
9
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
4.6
8.4
20
45
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
8.4
8
*
M34.1
ICD-10 Finland
CR(E)ST syndrome
+∞
8.4
8
*
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
8.4
8
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.3
8.3
65
301
RF420, ,
NOMESCO Finland
9.7
8.3
16
17
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
9.7
8.3
16
17
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
4.5
8.2
20
46
TQW80
NOMESCO Finland
Local dermatologic skincare
4.5
8.2
20
46
R52.2
ICD-10 Finland
Other chronic pain
3.8
8.1
25
69
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
33.9
8.1
10
*
ZXD05
NOMESCO Finland
Urgent procedure
1.8
8.1
160
1033
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
8.1
138
852
J05AB11
ATC
valaciclovir; oral
2.1
8.1
86
452
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.3
8.1
30
94
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
8.0
54
234
JN4AD
NOMESCO Finland
Body CT examination
2.4
8.0
58
260
J01MA12
ATC
levofloxacin; systemic
2.0
8.0
102
572
A08
ICPC
Swelling
3.1
8.0
34
116
N99
ICPC
Neurological disease other
7.9
7.9
17
22
N02AA05
ATC
oxycodone; systemic
2.0
7.9
89
477
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
7.9
176
1174
SBA10
NOMESCO Finland
Measurement of salivary flow rate
13.3
7.9
13
10
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.2
7.9
73
363
S29
ICPC
Skin symptom/complaint other
2.0
7.9
97
537
Z3231
NOMESCO Finland
Registered nurse
1.8
7.9
145
915
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.1
7.9
32
106
JDB10
NOMESCO Finland
Percutaneous gastrostomy
8.6
7.9
16
19
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.8
7.8
24
66
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.9
7.8
115
678
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.0
7.7
35
124
HA1AA
NOMESCO Finland
X-ray mammography
2.4
7.7
54
239
D07AC13
ATC
mometasone; topical
1.8
7.7
158
1030
R5110, ,
SPAT
3.0
7.6
34
119
-50
ICPC
Medication/prescr/renewal
3.5
7.6
26
77
D07AB02
ATC
hydrocortisone butyrate; topical
1.8
7.6
154
998
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
7.6
61
286
R06AE07
ATC
cetirizine; oral
1.7
7.6
218
1556
NH3EA
NOMESCO Finland
Feet X-ray examination with load
10.2
7.6
14
14
WX320
NOMESCO Finland
Spinalanesthesy
1.9
7.5
97
546
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
7.5
151
978
M01AH02
ATC
rofecoxib; oral
2.2
7.4
66
323
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.8
7.4
37
138
RF120, ,
NOMESCO Finland
13.6
7.4
12
9
SPAT1153
SPAT
Removal of sutures
1.8
7.4
151
981
XW000
NOMESCO Finland
Bone marrow biopsy
3.3
7.4
28
89
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
11.1
7.3
13
12
RF410, ,
NOMESCO Finland
11.1
7.3
13
12
G73.7*M35.0
ICD-10 Finland
Myopathy in sicca syndrome [Sjögren]
+∞
7.3
7
*
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
+∞
7.3
7
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
7.3
7
*
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
+∞
7.3
7
*
WX111
NOMESCO Finland
Local infiltration anesthesia
+∞
7.3
7
*
M60.1
ICD-10 Finland
Interstitial myositis
+∞
7.3
7
*
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
+∞
7.3
7
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.7
7.3
39
151
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
16.0
7.3
11
7
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
7.5
7.2
16
22
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.2
7.2
63
306
B01AC24
ATC
ticagrelor; oral
3.5
7.2
24
70
S92.3
ICD-10 Finland
Fracture of metatarsal bone
3.5
7.2
24
70
M01AX01
ATC
nabumetone; oral
3.4
7.2
26
80
Z2221
NOMESCO Finland
Medical doctor
1.8
7.2
144
929
ZXE00
NOMESCO Finland
One hour or less
1.7
7.2
196
1376
TQW40
NOMESCO Finland
Remowal of suture of skin
2.6
7.1
43
177
M01AB55
ATC
diclofenac, combinations; oral
2.8
7.1
35
130
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
4.0
7.0
20
52
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.9
7.0
33
119
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.9
7.0
33
119
ZXA00
NOMESCO Finland
Right side
1.8
7.0
128
803
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.8
6.9
34
126
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
6.9
92
523
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
8.4
6.9
14
17
R53
ICD-10 Finland
Malaise and fatigue
1.8
6.9
124
775
J01FA10
ATC
azithromycin; systemic
1.6
6.8
285
2216
A01AB09
ATC
miconazole; local oral
2.3
6.8
54
252
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.3
6.8
25
78
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
40.6
6.8
8
*
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
40.6
6.8
8
*
K90.0
ICD-10 Finland
Coeliac disease
3.5
6.8
23
68
M05BA01
ATC
etidronic acid; systemic
17.0
6.8
10
6
B01AA03
ATC
warfarin; systemic
1.9
6.8
95
549
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.0
6.7
80
437
TKC20
NOMESCO Finland
Catheterisation of bladder
2.5
6.7
41
170
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
4.1
6.7
18
45
SPAT1254
SPAT
Administration of medicine
2.0
6.6
73
388
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.7
6.6
34
129
SPAT1255
SPAT
Intravenous administration of medicine
2.7
6.6
35
135
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.9
6.6
19
50
ZXA05
NOMESCO Finland
Left side
1.8
6.6
117
727
A06AD11
ATC
lactulose; oral
1.9
6.6
82
455
SPAT1216
SPAT
Assessment of functional ability
2.0
6.5
78
426
J02AC01
ATC
fluconazole; systemic
1.6
6.5
199
1432
QC6S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in hand
70.7
6.4
7
*
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.1
6.4
26
86
RF210, ,
NOMESCO Finland
3.8
6.4
19
51
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
4.1
6.4
17
42
Z01.2
ICD-10 Finland
Dental examination
1.6
6.4
211
1543
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
6.4
190
1355
L84
ICD-10 Finland
Corns and callosities
3.4
6.3
22
66
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
6.3
95
562
M31.3
ICD-10 Finland
Wegener granulomatosis
+∞
6.3
6
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
+∞
6.3
6
*
L04AB01
ATC
etanercept; parenteral
+∞
6.3
6
*
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
+∞
6.3
6
*
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
6.3
6
*
127
Kela drug reimbursment
Transplant complication
7.2
6.3
14
20
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
27.0
6.2
8
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
6.2
310
2493
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
6.1
55
270
D07AA02
ATC
hydrocortisone; topical
2.0
6.1
72
391
K08.3
ICD-10 Finland
Retained dental root
2.4
6.1
42
184
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.5
6.1
37
153
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
6.1
68
363
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
3.3
6.1
22
68
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
10.2
6.1
11
11
A02BA02
ATC
ranitidine; systemic
1.8
6.0
106
655
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
6.1
6.0
15
25
SBA00
NOMESCO Finland
Microbiological examinations
4.0
6.0
17
44
SAA04
NOMESCO Finland
Special examination of mouth
2.8
6.0
30
112
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
163
121
18.98
183.22
5.8
2.2
535.02
672.10
ug/l
0.13
158
113
393
1150
10.25
148.64
11.8
2.0
238.00
321.40
u/l
0.47
388
1094
109
60
22.59
140.37
1.7
1.1
50.04
—
u/ml
—
10
0
111
91
15.15
115.83
2.1
1.2
—
—
—
0
0
117
8
186.85
115.52
1.3
1.0
—
—
—
0
0
98
78
15.18
103.67
1.6
1.1
12.35
5.90
u/ml
—
25
8
97
78
14.99
101.95
1.5
1.1
1.81
3.20
u/ml
—
13
7
79
73
12.53
75.62
1.5
1.5
275.23
0.19
iu/ml
0.47
12
14
383
1757
5.21
69.73
17.0
4.8
2.60
2.88
%
2.13
376
1632
381
1795
4.95
65.49
16.5
4.7
59.36
56.77
%
3.86
375
1680
384
1823
4.98
65.25
17.0
4.9
25.98
28.15
%
3.75
378
1704
64
5
145.13
61.34
1.2
1.0
—
—
—
0
0
44
20
23.89
60.25
1.4
1.2
—
—
—
0
0
44
20
23.89
60.25
1.4
1.2
—
—
—
0
0
44
20
23.89
60.25
1.4
1.2
—
—
—
0
0
44
20
23.89
60.25
1.4
1.2
—
—
—
0
0
44
20
23.89
60.25
1.4
1.2
—
—
—
0
0
418
2241
5.04
57.26
19.6
8.7
4.21
4.04
e9/l
0.88
402
1928
122
343
4.32
39.75
1.9
2.2
345.73
390.66
nmol/l
0.63
115
322
442
2894
4.12
36.21
12.7
3.0
15.07
11.55
mm/h
5.55
431
2622
329
1815
3.13
35.72
10.5
5.6
1.22
1.22
mmol/l
0.01
314
1634
346
1977
3.15
35.04
12.1
6.4
1.22
1.21
mmol/l
0.27
306
1668
190
780
3.23
34.52
2.0
1.4
2.25
2.46
g/l
0.65
147
450
296
1619
2.87
31.23
3.1
2.2
76.71
78.30
nmol/l
0.44
280
1425
319
1902
2.69
27.06
5.3
3.4
0.00
0.01
estimate
0.50
66
362
138
542
3.09
26.17
1.4
1.2
59.10
18.54
iu/ml
1.51
44
158
60
132
5.00
26.15
2.9
2.9
—
—
—
0
0
319
1927
2.64
25.94
5.4
3.4
0.00
0.02
estimate
0.80
67
331
252
1372
2.59
25.28
5.1
3.4
107.74
102.00
e6/l
0.03
185
970
315
1913
2.59
24.99
7.1
4.7
0.00
0.00
estimate
0.50
66
339
42
69
6.52
24.93
10.0
6.4
519.56
198.53
iu/ml
—
9
15
29
31
9.84
24.62
1.4
1.0
—
—
—
0
0
50
103
5.25
23.45
3.3
3.1
0.00
0.05
g/l
0.50
50
96
145
626
2.81
22.83
2.4
1.9
—
—
—
0
0
48
100
5.18
22.21
3.4
3.1
0.00
0.00
g/l
-0.00
48
93
48
100
5.18
22.21
3.4
3.1
0.00
0.00
g/l
-0.00
48
93
57
138
4.51
22.05
3.2
3.0
—
—
—
0
0
213
1143
2.44
21.17
4.6
2.9
1078.10
1287.33
ng/l
0.48
196
963
144
645
2.69
20.91
6.4
3.3
0.80
0.82
mmol/l
1.04
136
612
282
1733
2.33
20.30
7.4
4.5
34.02
35.75
g/l
4.83
273
1609
44
93
5.07
20.00
1.8
1.7
—
—
—
0
0
121
509
2.78
19.75
1.3
1.2
31.94
3.11
u/ml
1.03
35
188
75
244
3.41
19.10
2.4
2.5
12.77
24.49
au/ml
—
6
17
86
305
3.17
19.03
4.4
3.1
182.30
200.38
ng/l
0.18
78
288
44
98
4.80
18.81
1.3
1.2
—
—
—
0
0
117
498
2.73
18.58
2.9
2.3
23.23
23.78
%
0.14
102
430
160
800
2.43
18.13
3.2
2.3
2.87
6.32
e6/l
2.77
148
723
43
97
4.73
18.09
1.8
1.7
—
—
—
0
0
198
1089
2.30
18.01
4.3
2.8
0.26
0.60
e6/l
2.07
164
810
210
1196
2.25
17.45
4.2
2.9
76.23
70.13
e6/l
0.04
175
908
35
69
5.36
17.17
1.5
1.3
—
—
—
0
0
26
15
18.14
17.09
2.1
2.0
—
—
—
0
0
33
62
5.61
17.05
1.4
1.4
96.33
112.29
u/ml
—
6
7
104
439
2.70
16.66
2.3
1.8
—
—
—
0
0
34
68
5.27
16.42
1.7
1.5
—
—
—
0
0
28
22
13.37
16.33
1.5
1.1
2.20
—
u/ml
—
5
0
170
910
2.28
16.20
2.7
1.9
3.25
3.11
mg/l
0.27
152
751
133
645
2.42
15.88
3.5
2.5
0.68
1.03
e6/l
1.67
90
343
220
1315
2.15
15.85
6.3
3.0
47.93
33.23
u/l
2.41
210
1245
28
24
12.25
15.73
1.6
1.1
103.50
—
u/ml
—
8
0
34
71
5.05
15.64
1.8
1.6
—
—
—
0
0
34
71
5.05
15.64
1.8
1.6
—
—
—
0
0
166
903
2.22
15.05
4.0
2.6
2667.02
10250.72
umol/l
1.86
153
780
100
438
2.58
14.77
2.3
1.8
—
—
—
0
0
109
498
2.50
14.73
8.5
5.1
1.04
1.03
mmol/l
0.08
104
462
311
2156
2.07
14.69
8.9
6.5
10.01
11.25
umol/l
2.24
300
2037
33
71
4.89
14.66
1.2
1.2
—
—
—
0
0
41
108
4.03
14.14
5.5
5.4
33.76
29.96
mg/l
0.17
34
94
29
59
5.14
13.73
5.1
2.9
62.17
58.47
%
0.81
29
59
32
71
4.73
13.71
1.8
1.8
—
—
—
0
0
31
67
4.85
13.70
1.2
1.2
299.62
252.50
u/ml
0.29
21
34
26
48
5.64
13.66
1.9
1.4
—
—
—
0
0
26
48
5.64
13.66
1.9
1.4
—
—
—
0
0
27
52
5.42
13.57
1.1
1.2
2.92
7.50
u/ml
0.34
12
12
20
11
18.84
13.46
1.3
1.0
20.73
83.83
%
—
11
6
164
922
2.13
13.45
1.4
1.3
1.01
1.87
u/ml
0.71
34
233
40
108
3.92
13.34
5.6
5.4
44.32
49.79
mg/l
0.16
34
93
271
1832
1.98
13.25
17.2
12.7
1.29
1.23
inr
0.36
70
528
28
57
5.13
13.24
4.8
2.8
4.54
4.28
e9/l
0.25
28
57
24
24
10.42
12.60
1.6
1.1
4187.22
15198.17
e6/l
0.74
18
18
25
28
9.31
12.37
2.4
1.7
—
—
—
0
0
25
49
5.30
12.32
1.4
1.6
—
—
—
0
0
21
17
12.81
12.21
2.2
2.8
47.83
43.25
%
—
12
8
354
2671
1.97
12.04
6.3
4.0
15.40
3410.80
e6/l
—
5
40
26
56
4.83
11.53
1.3
1.5
—
—
—
0
0
92
433
2.36
11.48
13.4
7.4
10.55
12.48
kpa
3.87
82
416
92
433
2.36
11.48
13.4
7.4
5.20
5.06
kpa
0.58
82
413
247
1674
1.89
11.46
3.6
2.6
188.99
129.72
ug/l
1.66
234
1538
73
309
2.58
11.45
2.8
2.4
18.27
6.84
ug/l
2.46
64
271
68
281
2.63
11.19
2.1
1.5
—
—
—
0
0
137
773
2.04
10.82
6.1
3.9
237.73
306.77
ng/l
0.28
119
599
25
55
4.72
10.82
2.0
1.5
—
—
—
0
0
90
431
2.31
10.76
13.7
7.4
1.54
0.98
mmol/l
0.48
69
342
316
2348
1.85
10.67
9.0
4.5
6.65
6.76
mmol/l
0.46
305
2211
158
943
1.96
10.62
1.7
1.5
19.43
20.81
nmol/l
0.64
140
789
22
44
5.17
10.61
1.2
1.4
—
—
—
0
0
128
711
2.05
10.52
1.8
1.7
1146.33
1213.57
nmol/l
0.36
105
535
25
58
4.47
10.15
2.0
1.5
—
—
—
0
0
212
1412
1.83
10.05
3.5
3.7
2.33
2.36
mmol/l
2.36
196
1254
20
39
5.29
9.91
1.1
1.1
—
—
—
0
0
24
57
4.36
9.47
1.1
1.2
2.44
8.27
u/ml
—
9
26
22
49
4.64
9.38
1.5
1.2
—
—
—
0
0
221
1534
1.75
8.84
5.3
3.3
92.34
64.66
ng/l
0.44
188
1040
161
1020
1.83
8.76
6.6
3.3
0.00
0.01
estimate
0.80
66
334
111
625
1.98
8.65
3.9
2.6
3.35
2.47
e6/l
0.53
70
328
12
6
20.41
8.50
1.6
2.0
—
—
—
0
0
189
1271
1.76
8.34
2.7
2.3
54.14
62.66
u/l
1.19
176
1162
213
1483
1.73
8.30
5.9
3.5
—
—
—
0
0
21
50
4.33
8.27
1.7
1.9
—
—
—
0
0
20
46
4.48
8.21
1.7
2.0
—
—
—
0
0
136
834
1.85
8.14
2.2
1.7
1.26
1.18
mg/l
0.16
102
630
19
45
4.34
7.53
2.2
1.6
—
—
—
0
0
87
474
2.00
7.38
3.3
2.9
6.46
9.01
umol/l
1.07
74
416
17
25
6.99
7.34
1.1
1.2
—
—
—
0
0
14
15
9.55
7.32
1.0
1.2
—
—
—
0
0
18
42
4.40
7.27
1.8
2.3
—
—
—
0
0
46
195
2.49
7.17
18.4
9.9
24.64
24.38
mmol/l
0.17
41
190
224
1634
1.64
7.01
2.2
1.9
94.56
94.71
pmol/l
0.02
126
813
465
4114
2.03
6.97
32.0
12.3
19.46
25.26
mg/l
4.86
430
3121
11
8
14.00
6.91
1.9
1.4
8.37
8.96
ug/l
—
11
8
28
97
2.99
6.41
1.2
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
29
105
2.86
6.15
4.9
2.6
0.37
0.36
u/ml
0.10
19
62
13
17
7.81
6.15
2.0
1.5
—
—
—
0
0
16
41
3.99
5.75
1.5
1.8
—
—
—
0
0
16
41
3.99
5.75
1.5
1.8
—
—
—
0
0
16
41
3.99
5.75
1.5
1.8
—
—
—
0
0
126
831
1.68
5.66
6.7
3.4
1.02
1.02
kg/l
0.29
20
116
9
7
13.05
5.60
1.1
1.6
—
—
—
0
0
230
1757
1.54
5.57
3.3
2.4
—
—
—
0
0
31
123
2.61
5.56
1.4
1.1
—
—
—
0
0
14
25
5.72
5.40
1.0
1.1
—
—
—
0
0
24
85
2.91
5.31
2.5
1.4
—
—
—
0
0
30
122
2.55
5.13
1.3
1.1
—
—
—
0
0
13
23
5.77
5.09
1.1
1.1
0.11
0.33
nmol/l
—
5
5
46
228
2.11
5.03
2.0
1.7
—
—
—
0
0
9
10
9.13
4.80
1.0
1.0
90.72
284.97
iu/ml
—
9
10
15
35
4.38
4.66
1.1
1.0
—
—
—
0
0
11
18
6.22
4.62
1.7
3.5
1187.09
1188.72
u/ml
0.00
11
18
7
5
14.16
4.58
1.0
1.0
—
—
—
0
0
14
31
4.61
4.58
1.6
3.5
—
—
—
0
0
13
28
4.73
4.39
2.2
1.8
2.72
2.63
mg/l
0.08
13
28
43
222
2.02
4.25
1.6
1.4
—
—
—
0
0
32
147
2.25
4.24
2.7
2.0
—
—
—
0
0
319
2700
1.45
4.21
4.1
2.9
55.72
47.98
u/l
0.86
305
2505
9
13
7.02
4.17
2.1
1.4
38.80
82.58
u/l
—
9
13
121
848
1.55
4.13
1.6
1.6
61403947.26
10610906.58
pmol/l
0.38
114
688
65
389
1.76
4.10
2.4
2.4
361.22
40.45
u/l
0.48
55
328
8
10
8.10
4.07
1.3
2.8
—
—
—
0
0
14
42
3.40
4.07
1.0
1.1
—
—
—
0
0
17
58
2.99
4.04
1.1
1.1
—
—
—
0
0
10
18
5.64
3.99
1.0
1.0
—
—
—
0
0
61
365
1.76
3.86
6.1
3.5
2.14
1.76
mmol/l
0.37
54
303
114
808
1.52
3.67
2.4
3.1
2.47
2.45
mmol/l
0.74
97
719
22
93
2.42
3.53
1.4
1.3
—
—
—
0
0
22
93
2.42
3.53
1.4
1.3
—
—
—
0
0
8
13
6.23
3.51
1.1
1.0
—
—
—
0
0
39
209
1.93
3.50
1.4
1.3
—
—
—
0
0
13
43
3.07
3.27
3.4
2.2
90.52
89.17
%
0.55
13
43
9
19
4.80
3.25
1.0
1.1
—
—
—
0
0
26
127
2.10
3.02
1.6
1.1
—
—
—
0
0
5
5
10.08
2.98
3.8
1.4
—
—
—
0
0
27
135
2.05
2.96
2.5
1.8
—
—
—
0
0
8
17
4.76
2.93
1.5
1.2
—
—
—
0
0
11
33
3.38
2.82
1.2
1.2
—
—
—
0
0
10
28
3.62
2.79
1.5
1.8
—
—
—
0
0
151
1188
1.38
2.73
3.3
3.2
2193.45
167.73
mg/l
1.46
105
738
7
14
5.05
2.73
1.1
1.0
—
—
—
0
0
39
230
1.75
2.64
3.1
3.2
4.17
4.54
pmol/l
1.94
33
200
60
398
1.57
2.60
5.3
3.0
—
—
—
0
0
20
94
2.17
2.58
2.1
1.5
—
—
—
0
0
5
7
7.20
2.55
2.0
1.9
—
—
—
0
0
156
1255
1.34
2.42
3.1
3.0
6.91
7.37
mmol/l
0.67
137
1058
10
33
3.07
2.37
1.2
1.0
—
—
—
0
0
7
17
4.16
2.36
1.7
2.4
—
—
—
0
0
7
17
4.16
2.36
1.7
2.4
—
—
—
0
0
7
17
4.16
2.36
1.7
2.4
—
—
—
0
0
117
903
1.38
2.36
2.7
2.2
—
—
—
0
0
18
85
2.16
2.31
1.4
1.5
—
—
—
0
0
10
34
2.98
2.29
1.0
1.1
304.00
294.86
mg/l
—
10
28
10
34
2.98
2.29
1.3
1.2
—
—
—
0
0
8
23
3.51
2.27
1.3
1.1
—
—
—
0
0
8
23
3.51
2.27
1.3
1.1
—
—
—
0
0
354
3206
1.31
2.27
4.9
3.8
14.98
14.80
pmol/l
0.69
331
2884
19
359
0.51
2.22
1.7
1.8
—
—
—
0
0
11
41
2.72
2.22
1.4
1.3
—
—
—
0
0
8
24
3.37
2.18
1.6
2.0
—
—
—
0
0
8
24
3.37
2.18
1.6
2.0
—
—
—
0
0
35
213
1.69
2.16
1.0
1.0
—
—
—
0
0
23
126
1.86
2.01
1.3
1.5
295.13
285.51
ug/g
0.08
15
77
413
3851
1.32
1.96
5.8
4.6
1.90
2.24
mu/l
0.53
391
3488
5
11
4.58
1.94
1.2
1.2
—
—
—
0
0
7
22
3.21
1.88
1.6
1.5
—
—
—
0
0
7
22
3.21
1.88
1.6
1.5
—
—
—
0
0
7
22
3.21
1.88
1.0
1.1
—
—
—
0
0
13
59
2.23
1.85
1.2
1.1
—
—
—
0
0
6
17
3.56
1.84
2.5
1.4
—
—
—
0
0
6
17
3.56
1.84
2.5
1.4
—
—
—
0
0
5
13
3.87
1.72
1.0
1.2
—
—
—
0
0
5
13
3.87
1.72
1.0
1.1
—
—
—
0
0
5
13
3.87
1.72
1.0
1.1
1323.80
1260.31
miu/ml
—
5
13
6
19
3.18
1.66
2.0
2.5
37883.33
36363.42
ug/l
—
6
19
6
19
3.18
1.66
2.0
1.4
—
—
—
0
0
7
26
2.71
1.58
1.6
1.4
—
—
—
0
0
6
20
3.02
1.58
1.0
1.4
—
—
—
0
0
148
1247
1.26
1.56
3.6
3.7
7.19
9.61
mg/mmol
0.44
92
770
18
100
1.83
1.55
1.4
1.7
3.80
5.21
iu/l
—
7
34
14
73
1.94
1.45
3.2
2.0
114.00
132.36
g/l
—
7
55
42
296
1.45
1.45
2.7
2.7
69.62
68.01
ml/min/173m2
0.05
13
124
13
66
1.99
1.44
1.5
1.1
—
—
—
0
0
9
39
2.33
1.43
3.6
2.3
—
—
—
0
0
9
40
2.27
1.40
4.0
3.7
—
—
—
0
0
9
42
2.16
1.34
1.2
1.0
—
—
—
0
0
20
121
1.68
1.32
1.5
1.6
—
—
—
0
0
22
137
1.63
1.31
1.3
1.4
—
—
—
0
0
6
24
2.52
1.30
2.5
1.4
—
—
—
0
0
6
24
2.52
1.30
2.5
1.4
—
—
—
0
0
452
4336
1.28
1.25
30.8
14.8
139.33
139.72
mmol/l
2.35
442
4194
467
4501
1.31
1.23
25.4
9.2
30.96
25.70
u/l
6.96
460
4315
62
484
1.32
1.20
2.4
4.3
3.13
39.50
ug/l
1.44
49
407
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
26
2.32
1.19
1.2
1.2
—
—
—
0
0
381
4008
0.83
1.18
4.6
3.9
1.53
1.27
mmol/l
4.62
359
3644
397
4156
0.82
1.14
4.9
4.3
1.40
1.50
mmol/l
4.92
374
3809
7
31
2.27
1.10
2.1
1.3
0.96
1.01
g/l
—
7
31
452
4354
1.25
1.08
31.1
14.9
3.94
3.97
mmol/l
1.41
442
4206
401
4187
0.83
1.07
4.9
4.3
4.80
4.72
mmol/l
0.87
377
3863
81
669
1.25
1.03
1.5
1.4
—
—
—
0
0
10
53
1.90
1.02
1.7
1.5
—
—
—
0
0
10
53
1.90
1.02
1.7
1.5
—
—
—
0
0
10
53
1.90
1.02
1.7
1.5
—
—
—
0
0
13
76
1.73
0.99
4.2
2.1
15.22
16.50
%
—
5
39
10
54
1.87
0.97
1.7
1.5
—
—
—
0
0
10
55
1.83
0.92
1.7
1.5
—
—
—
0
0
10
55
1.83
0.92
1.7
1.5
—
—
—
0
0
19
126
1.53
0.92
1.9
1.7
—
—
—
0
0
24
168
1.45
0.91
7.6
5.5
2.05
1.56
%
2.36
19
157
14
87
1.63
0.88
1.1
1.1
—
—
—
0
0
14
89
1.59
0.82
3.0
3.6
31.71
27.34
mg/l
—
8
57
13
81
1.62
0.82
1.1
1.3
—
—
—
0
0
57
466
1.25
0.81
1.4
1.7
1.48
1.43
%
0.30
46
410
412
4263
0.85
0.81
5.2
4.8
2.88
2.79
mmol/l
1.28
391
3909
10
58
1.74
0.80
1.0
1.3
—
0.87
nmol/l
—
0
6
416
4012
1.17
0.77
24.8
11.9
85.51
80.91
ml/min/173m2
3.32
370
3237
6
34
1.77
0.76
1.3
1.2
—
—
—
0
0
5
24
2.09
0.74
1.2
1.4
1.82
1.58
g/l
—
5
24
10
60
1.68
0.72
1.2
1.6
—
—
—
0
0
5
26
1.93
0.71
1.0
1.1
—
—
—
0
0
25
193
1.31
0.58
2.7
3.4
20.35
1911.41
u/ml
1.25
20
166
127
1153
1.13
0.58
1.7
1.6
1.63
1.37
mmol/l
2.00
110
958
6
37
1.63
0.55
2.0
2.4
13.67
12.99
%
—
6
37
32
259
1.25
0.54
1.3
1.2
96.09
126.86
iu/ml
—
8
98
7
47
1.50
0.47
2.0
2.0
—
11.74
—
0
14
258
2460
1.09
0.47
3.2
2.9
—
—
—
0
0
27
328
0.81
0.44
2.8
1.8
—
—
—
0
0
397
3872
1.10
0.41
6.5
5.5
40.16
39.91
mmol/mol
0.23
378
3555
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
6
43
1.40
0.35
1.0
1.0
—
—
—
0
0
123
1154
1.09
0.32
4.6
4.9
3.80
2.84
ug/l
0.37
112
1033
5
42
1.19
0.21
1.2
1.4
—
—
—
0
0
6
49
1.23
0.20
2.2
1.6
—
—
—
0
0
10
121
0.82
0.18
1.4
1.4
—
—
—
0
0
57
533
1.08
0.18
5.0
4.3
30.82
32.02
%
0.42
45
346
34
370
0.91
0.16
2.5
2.0
—
—
—
0
0
6
77
0.78
0.15
1.5
1.5
—
—
—
0
0
473
4695
1.07
0.15
43.9
18.3
260.92
249.90
e9/l
2.00
467
4542
473
4696
1.07
0.15
45.1
18.4
39.64
41.16
%
0.82
435
4363
21
189
1.12
0.14
2.0
1.9
—
—
—
0
0
91
947
0.95
0.13
3.6
4.2
22.86
21.77
%
0.33
44
449
473
4699
1.06
0.13
43.8
18.3
4.36
4.50
e12/l
7.40
466
4533
9
109
0.82
0.13
1.4
1.2
—
—
—
0
0
72
694
1.04
0.10
1.6
1.4
—
—
—
0
0
5
47
1.06
0.09
1.2
1.7
—
—
—
0
0
5
48
1.04
0.09
1.4
1.4
31.30
28.77
u/l
—
5
39
52
501
1.04
0.07
9.6
6.3
—
—
—
0
0
7
80
0.87
0.07
1.4
1.6
—
—
—
0
0
71
690
1.03
0.07
2.7
2.9
0.73
0.77
ug/l
0.26
48
451
16
148
1.08
0.06
2.1
1.8
—
—
—
0
0
407
4090
0.98
0.05
5.0
4.4
5.75
5.95
mmol/l
3.01
380
3706
13
120
1.09
0.05
1.8
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.6
1.3
7.84
7.40
mmol/l
—
5
44
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
96.58
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
1.24
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint DERMATOPOLY_FG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DERMATOPOLY_FG | 2.299 [1.97, 2.68] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.13 |
During the follow-up period (1.1.1998 — 31.12.2019), 396 out of 1305 females with DERMATOPOLY_FG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| DERMATOPOLY_FG | 2.482 [2.06, 3.0] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 296 out of 812 males with DERMATOPOLY_FG died.
Mortality risk
Mortality risk for people of age
years, who have DERMATOPOLY_FG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.186% | 0.452% |
| 5 | 1.199% | 2.697% |
| 10 | 3.158% | 6.784% |
| 15 | 5.816% | 11.73% |
| 20 | 10.511% | 19.65% |
Relationships between endpoints
↥Index endpoint: DERMATOPOLY_FG – Dermatopolymyositis (FG)
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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