pyelonephritis: Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.
Renal tubulo-interstitial disorders in diseases classified elsewhere
DOID EFO Endpoint Browser PheWeb
N14_RENALTUBULOINOTH
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
351 |
4. Check minimum number of eventsNone |
351 |
5. Include endpointsNone |
351 |
6. Filter based on genotype QC (FinnGen only) |
338 |
Control definitions (FinnGen only)
- Control exclude
- N14_RENALTUB
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Renal tubulo-interstitial disorders in diseases classified elsewhere
based on the number of shared cases.
Similar with more cases:
- All chronic kidney diseases
- Renal tubulo-interstitial diseases
- All kidney diseases
- Genitourinary diseases
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1856 | 880 | 962 |
| Only index persons | 1584 | 749 | 835 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.03 |
| Only index persons | 0.03 | 0.03 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 62.48 | 63.34 | 61.63 |
| Only index persons | 62.08 | 62.77 | 61.46 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 338 | 160 | 178 |
| Unadjusted period prevalence (%) | 0.07 | 0.06 | 0.08 |
| Median age at first event (years) | 58.88 | 55.99 | 61.47 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 351
- Matched controls
- 3510
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
294.3
158.6
151
9
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
105.0
155.8
81
10
N19
ICD-10 Finland
Unspecified kidney failure
69.0
137.0
76
14
L04AA06
ATC
mycophenolic acid; systemic
83.5
136.0
73
11
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
44.6
125.6
77
22
B03XA02
ATC
darbepoetin alfa; parenteral
72.3
118.4
65
11
N16.2*D86.8
ICD-10 Finland
Renal tubulo-interstitial disorders in sarcoidosis
+∞
115.1
104
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
+∞
104.5
95
*
A11CC03
ATC
alfacalcidol; systemic
454.0
102.9
98
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
19.4
99.0
84
56
KA1AE
NOMESCO Finland
Kidney ultrasound examination
40.8
97.9
61
18
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
+∞
92.9
85
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
372.2
88.0
85
*
N18.8
ICD-10 Finland
Other chronic renal failure
186.1
84.3
85
6
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.9
80.9
130
218
L04AX01
ATC
azathioprine; systemic
17.2
80.8
72
52
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
13.7
80.8
84
79
M04AA01
ATC
allopurinol; systemic
8.6
80.4
134
234
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
12.1
79.0
90
97
A12AA04
ATC
calcium carbonate; oral
449.2
73.6
71
*
C03CA01
ATC
furosemide; systemic
6.9
73.4
212
634
TK800
NOMESCO Finland
Hemodialysis
177.2
69.9
71
5
Z94.0
ICD-10 Finland
Kidney transplant status
+∞
64.6
60
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
120.1
64.5
68
7
D86.0
ICD-10 Finland
Sarcoidosis of lung
31.7
63.0
42
15
Z49.1
ICD-10 Finland
Extracorporeal dialysis
674.7
59.5
57
*
127
Kela drug reimbursment
Transplant complication
86.5
58.4
64
9
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
+∞
56.8
53
*
N18.0
ICD-10 Finland
End-stage renal disease
+∞
56.8
53
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.4
54.2
270
1204
L04AD01
ATC
ciclosporin; systemic
23.6
54.0
40
19
N16.3*E83.50
ICD-10 Finland
Nefrocalcinosis NEC
+∞
52.4
49
*
E83.50
ICD-10 Finland
Hypercalcemia
84.6
51.8
57
8
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
297.2
51.6
51
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.1
50.8
200
727
M10.9
ICD-10 Finland
Gout, unspecified
8.3
50.0
74
109
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
9.3
49.8
66
85
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.7
48.5
92
177
H02AB04
ATC
methylprednisolone; systemic
5.5
46.4
118
297
Z49.0
ICD-10 Finland
Preparatory care for dialysis
+∞
45.8
43
*
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
+∞
45.8
43
*
137
Kela drug reimbursment
Uraemia requiring dialysis
+∞
45.8
43
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
13.5
44.5
44
37
205
Kela drug reimbursment
Chronic hypertension
4.5
43.0
165
573
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
42.6
40
*
L04AD02
ATC
tacrolimus; systemic
125.3
41.8
44
*
B05DA
ATC
Isotonic solutions
+∞
40.4
38
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
8.0
39.9
59
86
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
+∞
39.3
37
*
132
Kela drug reimbursment
Sarcoidosis
95.2
38.7
42
5
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.8
38.6
116
330
Z49.2
ICD-10 Finland
Other dialysis
+∞
37.1
35
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
+∞
37.1
35
*
N16.1*C90.0
ICD-10 Finland
Renal tubulo-interstitial disorders in multiple myeloma
+∞
37.1
35
*
M05BA04
ATC
alendronic acid; oral
6.3
36.8
70
133
ZX120
NOMESCO Finland
Intravenous
5.6
35.4
78
170
N16.3*M10.9
ICD-10 Finland
Gout nephropathy
+∞
33.9
32
*
B05DB
ATC
Hypertonic solutions
+∞
33.9
32
*
JN3AD
NOMESCO Finland
Abdominal CT examination
5.2
32.7
79
186
M10.0
ICD-10 Finland
Idiopathic gout
9.7
32.5
40
46
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
11.0
32.4
36
36
V03AE01
ATC
polystyrene sulfonate; oral
125.1
32.3
34
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.4
32.0
72
159
C08CA01
ATC
amlodipine; oral
3.7
32.0
198
914
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.4
31.2
70
154
JN4AD
NOMESCO Finland
Body CT examination
5.2
31.2
74
171
Z2446
NOMESCO Finland
Social worker
6.3
31.2
58
107
A10AC01
ATC
insulin (human); parenteral
5.8
30.4
62
125
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
62.5
29.7
34
6
N16.2
ICD-10 Finland
Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism
+∞
29.6
28
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
+∞
29.6
28
*
L04AA01
ATC
[U] ciclosporin
48.4
29.3
35
8
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.1
28.9
103
326
C08CA02
ATC
felodipine; oral
5.2
28.8
68
156
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
7.9
27.7
40
56
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
41.6
27.6
34
9
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
+∞
27.5
26
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
10.8
26.9
30
30
V03AE02
ATC
sevelamer; oral
+∞
26.4
25
*
B03XA01
ATC
erythropoietin; parenteral
101.2
26.1
28
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
7.0
25.9
42
67
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
32.9
25.5
33
11
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
6.6
25.5
44
75
GD1AD
NOMESCO Finland
Thorax CT examination
6.2
25.4
47
86
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.7
25.1
100
339
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
+∞
24.2
23
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
+∞
24.2
23
*
H02AB06
ATC
prednisolone; systemic
3.1
24.0
215
1176
H05BX01
ATC
cinacalcet; oral
134.2
23.9
25
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.7
23.4
39
64
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
+∞
23.2
22
*
A10AB05
ATC
insulin aspart; parenteral
5.1
22.8
52
115
A12BA01
ATC
potassium chloride; oral
7.6
22.4
33
47
C90.0
ICD-10 Finland
Multiple myeloma
27.2
22.1
30
12
N16.5*T86.9
ICD-10 Finland
Renal tubulo-interstitial disorder in transplant rejection
+∞
22.1
21
*
Z3231
NOMESCO Finland
Registered nurse
3.0
22.1
143
646
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
7.7
22.0
32
45
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
21.9
117
473
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.2
21.4
64
176
R50.9
ICD-10 Finland
Fever, unspecified
3.6
21.3
83
275
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
20.9
146
684
XW000
NOMESCO Finland
Bone marrow biopsy
6.0
20.8
39
72
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
7.7
20.7
30
42
ZX108
NOMESCO Finland
Inhalation
34.9
20.5
26
8
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.0
20.2
66
193
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
+∞
20.0
19
*
N16.4*M35.0
ICD-10 Finland
Sjögren's syndrome with renal tubulo-interstitial disorders
+∞
20.0
19
*
D64.9
ICD-10 Finland
Anaemia, unspecified
4.0
19.9
63
180
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.4
19.0
40
82
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.9
19.0
64
191
A41.9
ICD-10 Finland
Sepsis, unspecified
7.5
18.9
28
40
TK820
NOMESCO Finland
Peritoneal dialysis
+∞
18.9
18
*
N16.4*M32.1
ICD-10 Finland
Renal tubulo-interstitial disorders in systemic lupus erythematosus
+∞
18.9
18
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
+∞
18.9
18
*
TK810
NOMESCO Finland
Hemofiltration
+∞
18.9
18
*
B01AB10
ATC
tinzaparin; parenteral
3.9
18.4
60
175
C09AA02
ATC
enalapril; systemic
3.1
18.4
101
410
ZXD05
NOMESCO Finland
Urgent procedure
2.8
18.3
141
686
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
6.4
18.1
31
52
A12AA12
ATC
[U] calcium acetate
+∞
17.9
17
*
V03AE03
ATC
lanthanum carbonate; oral
+∞
17.9
17
*
M05BX04
ATC
denosumab; parenteral
5.1
17.8
40
87
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
100.2
17.7
19
*
C07AB07
ATC
bisoprolol; oral
2.7
17.6
213
1289
J01MA12
ATC
levofloxacin; systemic
3.0
17.4
96
389
153
Kela drug reimbursment
Lenalidomid
33.4
17.2
22
7
L04AX04
ATC
lenalidomide; oral
33.4
17.2
22
7
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
17.1
117
532
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
16.1
17.0
27
18
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
6.9
16.9
27
42
Z3226
NOMESCO Finland
Physiotherapist
2.9
16.9
98
408
U14
ICPC
Kidney symptom/complaint
37.1
16.9
21
6
N17.8
ICD-10 Finland
Other acute renal failure
+∞
16.8
16
*
321
Kela drug reimbursment
Paricalcitol and cinacalcet
94.7
16.7
18
*
3AC01, ,
NOMESCO Finland
29.2
16.7
22
8
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
29.2
16.7
22
8
I50.0
ICD-10 Finland
Congestive heart failure
4.5
16.4
43
106
R4110
NOMESCO Finland
Physiotherapy
2.6
16.4
134
665
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
50.0
16.2
19
*
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
15.9
77
288
I50.9
ICD-10 Finland
Heart failure, unspecified
3.3
15.9
71
253
C07AG02
ATC
carvedilol; oral
4.5
15.9
42
104
K65.0
ICD-10 Finland
Acute peritonitis
35.2
15.9
20
6
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
+∞
15.7
15
*
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
+∞
15.7
15
*
J01FF01
ATC
clindamycin; systemic
2.6
15.6
126
619
C02AC05
ATC
moxonidine; oral
5.2
15.3
33
69
J01MA02
ATC
ciprofloxacin; systemic
2.5
15.1
156
857
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
15.0
98
432
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
33.3
15.0
19
6
A46
ICD-10 Finland
Erysipelas
3.1
14.9
73
275
A07AA09
ATC
vancomycin; oral
26.4
14.9
20
8
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
+∞
14.7
14
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
+∞
14.7
14
*
H02AB07
ATC
prednisone; oral
3.1
14.6
73
278
A02BC02
ATC
pantoprazole; systemic
2.7
14.6
267
1894
XF400
NOMESCO Finland
ECG with 12 standard connections
2.9
14.4
80
323
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.2
14.3
65
234
WW200
NOMESCO Finland
Immunization
10.7
14.2
27
27
Z2221
NOMESCO Finland
Medical doctor
2.5
14.2
126
643
J01MA14
ATC
moxifloxacin; systemic
3.5
14.1
52
164
A10AE04
ATC
insulin glargine; parenteral
3.5
14.0
54
175
C09CA01
ATC
losartan; oral
2.5
14.0
120
602
KBV00
NOMESCO Finland
Insertion of stent into ureter
55.7
13.9
16
*
XG410
NOMESCO Finland
Flow-volume spirometry
5.0
13.8
31
67
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.0
13.8
42
116
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.5
13.8
114
562
N02AX02
ATC
tramadol; systemic, rectal
2.3
13.7
181
1096
WX002
NOMESCO Finland
Sedation and analgesia
2.6
13.7
97
443
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
+∞
13.6
13
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
+∞
13.6
13
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.1
13.6
39
103
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.6
13.6
48
147
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
145.4
13.5
14
*
E87.5
ICD-10 Finland
Hyperkalaemia
14.6
13.4
22
16
212
Kela drug reimbursment
Gout
11.6
13.2
24
22
ZXE00
NOMESCO Finland
One hour or less
2.3
13.2
163
956
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
20.0
13.1
19
10
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
13.0
147
829
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
13.0
58
206
R4190
NOMESCO Finland
Nutritional therapy
5.7
13.0
25
47
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
52.0
12.9
15
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
6.1
12.9
23
40
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.9
12.8
29
63
S97
ICPC
Chronic ulcer skin
3.9
12.7
40
113
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
+∞
12.6
12
*
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
+∞
12.6
12
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
12.6
12
*
WX892
NOMESCO Finland
Monitored bed care
3.7
12.5
43
129
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
11.1
12.4
23
22
A10AE05
ATC
insulin detemir; parenteral
4.3
12.4
33
82
WX402
NOMESCO Finland
General anaesthesia
2.6
12.3
90
415
329
Kela drug reimbursment
Lenalidomide
27.8
12.1
16
6
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
22.2
12.1
17
8
N18.3
ICD-10 Finland
Chronic kidney disease, stage 3
22.2
12.1
17
8
SPAT1262
SPAT
Handing over of treatment supplies
2.7
12.1
78
338
B01AA03
ATC
warfarin; systemic
2.6
12.1
87
398
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.4
12.1
47
153
A10BH05
ATC
linagliptin; oral
4.5
12.0
30
71
RD210, ,
NOMESCO Finland
13.2
11.8
20
16
C07AB02
ATC
metoprolol; systemic
2.5
11.8
88
410
H02AB09
ATC
hydrocortisone; systemic
9.8
11.7
23
25
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.4
11.6
44
141
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
+∞
11.5
11
*
N16.3*M10.0
ICD-10 Finland
Nephropathy caused by gout
+∞
11.5
11
*
N16.0*A02.2
ICD-10 Finland
Salmonella renal tubulo-interstitial disease
+∞
11.5
11
*
N16.3
ICD-10 Finland
Renal tubulo-interstitial disorders in metabolic diseases
+∞
11.5
11
*
3025
Kela drug reimbursment
Calcium carbonate
+∞
11.5
11
*
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
5.7
11.5
22
41
WW400
NOMESCO Finland
Plasmaferesis
123.9
11.5
12
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
123.9
11.5
12
*
E86
ICD-10 Finland
Volume depletion
9.4
11.4
23
26
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.4
11.3
29
70
C08CA13
ATC
lercanidipine; oral
2.7
11.2
69
291
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
3.1
11.2
52
188
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.8
11.1
62
249
C10AA05
ATC
atorvastatin; oral
2.1
11.1
172
1086
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.7
11.0
36
104
WX610
NOMESCO Finland
Patient controlled analgesia
44.8
11.0
13
*
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
12.5
11.0
19
16
J01DB01
ATC
cefalexin; oral
2.8
10.8
302
2408
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
5.5
10.7
21
40
KH1AD
NOMESCO Finland
CT of urinary organs
5.5
10.7
21
40
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.2
10.7
46
159
M01AE01
ATC
ibuprofen; systemic, rectal
0.5
10.6
228
2819
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
+∞
10.5
10
*
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
+∞
10.5
10
*
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
+∞
10.5
10
*
KAS40
NOMESCO Finland
Excision of transplanted kidney
+∞
10.5
10
*
N25.0
ICD-10 Finland
Renal osteodystrophy
+∞
10.5
10
*
N02AA05
ATC
oxycodone; systemic
2.5
10.5
79
368
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.6
10.4
36
108
WX204
NOMESCO Finland
Axillary plexus blockaced
4.6
10.4
25
57
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
9.2
10.4
21
24
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
10.4
161
1008
P01BA02
ATC
hydroxychloroquine; oral
3.2
10.1
43
148
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
26.9
9.9
13
5
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.1
9.8
129
755
A02BC01
ATC
omeprazole; systemic
2.2
9.8
113
629
RS220, ,
NOMESCO Finland
13.9
9.8
16
12
XF600
NOMESCO Finland
Bloodpressure measurement
3.6
9.7
33
98
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.7
9.7
23
52
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.7
9.7
23
52
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.8
9.7
20
24
WW500
NOMESCO Finland
Blood transfusion
4.2
9.7
26
65
ZXA05
NOMESCO Finland
Left side
2.2
9.7
104
563
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
9.5
9.6
19
21
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
10.5
9.6
18
18
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.9
9.6
50
193
A28
ICPC
Limited function/disability NOS
2.5
9.6
71
327
ZXA00
NOMESCO Finland
Right side
2.2
9.5
112
628
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.2
9.5
39
131
WX2DD
NOMESCO Finland
Low-dose CT of skeleton in whole body
102.7
9.5
10
*
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
+∞
9.4
9
*
N165, T861,
ICD-10 Finland
+∞
9.4
9
*
H05BX02
ATC
paricalcitol; systemic
+∞
9.4
9
*
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
+∞
9.4
9
*
R11
ICD-10 Finland
Nausea and vomiting
3.0
9.4
43
154
103
Kela drug reimbursment
Diabetes, insulin-treated
2.2
9.4
109
607
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
9.4
55
226
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
9.3
143
885
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.5
9.3
23
54
RS221, ,
NOMESCO Finland
14.2
9.3
15
11
A06AD11
ATC
lactulose; oral
2.6
9.2
61
266
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
9.2
225
1638
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
11.9
9.2
16
14
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.0
9.1
26
68
WX872
NOMESCO Finland
Intensive care
3.6
9.1
31
92
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
16.1
9.1
14
9
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
9.1
69
321
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.3
9.1
35
113
D86
ICD-10 Finland
Sarcoidosis
37.7
9.1
11
*
I41.8*D86.8
ICD-10 Finland
Sarcoid myocarditis
37.7
9.1
11
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
9.1
106
591
GD2SN
NOMESCO Finland
Lung ventilation SPECT
24.8
9.0
12
5
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
9.0
92
487
B07.9
ICD-10 Finland
Verruca simplex
5.1
8.9
19
39
UKC02
NOMESCO Finland
Cystoscopy
2.5
8.9
66
303
BBA30
NOMESCO Finland
Excision of lesion of parathyroid gland
14.5
8.8
14
10
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
16.8
8.6
13
8
H26.3
ICD-10 Finland
Drug-induced cataract
16.8
8.6
13
8
AA1AD
NOMESCO Finland
CT of head and brain
2.1
8.6
106
602
UJF32
NOMESCO Finland
Coloscopy
2.1
8.5
104
587
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
20.6
8.5
12
6
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
8.5
53
224
WX720
NOMESCO Finland
Own respiration
3.8
8.5
26
72
L03AA02
ATC
filgrastim; parenteral
4.8
8.5
19
41
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
92.2
8.4
9
*
E21.2
ICD-10 Finland
Other hyperparathyroidism
92.2
8.4
9
*
A04AA01
ATC
ondansetron; systemic, rectal
2.9
8.4
41
152
B01AB04
ATC
dalteparin; parenteral
3.7
8.4
27
77
C02EA02, ,
ATC
4.0
8.4
24
63
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
+∞
8.4
8
*
N16.0
ICD-10 Finland
Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere
+∞
8.4
8
*
NF1AA
NOMESCO Finland
Hip X-ray examination
2.9
8.3
42
159
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.9
8.3
40
148
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
8.2
98
549
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
17.7
8.1
12
7
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
34.2
8.1
10
*
M10
ICD-10 Finland
Gout
3.8
8.0
25
70
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.7
8.0
26
75
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
4.8
8.0
18
39
TGC00
NOMESCO Finland
Bronchial lavation
4.8
8.0
18
39
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.4
8.0
58
264
RS222, ,
NOMESCO Finland
13.4
7.9
13
10
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
7.8
86
465
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
46.0
7.7
9
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.1
7.7
94
528
A10AB01
ATC
insulin (human); parenteral
4.2
7.7
21
53
N03AX16
ATC
[U] pregabalin
2.1
7.7
92
513
XCK10
NOMESCO Finland
Photography of fundus of eye
2.7
7.7
45
184
A41.8
ICD-10 Finland
Other specified sepsis
8.3
7.7
16
20
N18
ICD-10 Finland
Chronic kidney disease
18.9
7.6
11
6
KBV10
NOMESCO Finland
Removal of stent from ureter
25.6
7.6
10
*
T89
ICPC
Diabetes insulin dependent
3.8
7.6
23
63
UJF30
NOMESCO Finland
Ileoscopy through colon
2.6
7.6
47
198
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
7.5
26
78
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.9
7.5
37
138
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.7
7.5
18
28
M81.4
ICD-10 Finland
Drug-induced osteoporosis
81.8
7.4
8
*
TJW99
NOMESCO Finland
Other minor procedure in gastrointestinal endoscopy
81.8
7.4
8
*
N05CF01
ATC
zopiclone; oral
1.9
7.3
121
755
Z99.2
ICD-10 Finland
Dependence on renal dialysis
+∞
7.3
7
*
V03AE04
ATC
calcium acetate and magnesium carbonate; systemic
+∞
7.3
7
*
187
Kela drug reimbursment
MPA
+∞
7.3
7
*
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
+∞
7.3
7
*
K65.9
ICD-10 Finland
Peritonitis, unspecified
+∞
7.3
7
*
A12AA06
ATC
calcium lactate gluconate; oral
+∞
7.3
7
*
TK830
NOMESCO Finland
Ultrafiltration
+∞
7.3
7
*
5901A
ICD-9 Finland
Infections of kidney, Acute pyelonephritis
+∞
7.3
7
*
J01EA01
ATC
trimethoprim; systemic
2.1
7.3
87
484
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
4.5
7.3
18
42
I50
ICD-10 Finland
Heart failure
4.7
7.3
17
38
C08CA05
ATC
nifedipine; systemic
3.1
7.2
31
107
R80
ICD-10 Finland
Isolated proteinuria
30.7
7.2
9
*
NHQ40
NOMESCO Finland
Amputation of toe
8.2
7.2
15
19
E83.51
ICD-10 Finland
Hypocalcemia
20.5
7.2
10
5
M13.9
ICD-10 Finland
Arthritis, unspecified
2.8
7.2
36
136
SPAT1255
SPAT
Intravenous administration of medicine
3.2
7.1
29
97
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
7.1
46
198
E87.6
ICD-10 Finland
Hypokalaemia
4.0
7.1
20
52
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.2
7.1
28
92
ZXD20
NOMESCO Finland
Day surgery
2.3
6.9
54
253
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.0
6.9
87
493
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.8
6.9
36
139
288
Kela drug reimbursment
Febuxostat
40.9
6.8
8
*
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
17.1
6.8
10
6
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.9
6.7
20
54
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
6.7
71
377
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
23.0
6.7
9
*
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
5.7
6.7
18
33
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
10.3
6.6
12
12
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.4
6.6
24
75
S01BA04
ATC
prednisolone; ophthalmic
6.4
6.5
16
26
A07AA02
ATC
nystatin; oral
3.1
6.5
27
91
N20.1
ICD-10 Finland
Calculus of ureter
4.1
6.5
18
46
TKC20
NOMESCO Finland
Catheterisation of bladder
2.9
6.5
30
108
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
6.5
107
664
Y83.0
ICD-10 Finland
Surgical operation with transplant of whole organ as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
71.1
6.4
7
*
1350A
ICD-9 Finland
Sarcoidosis[SARCOIDOSIS]
71.1
6.4
7
*
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
14.7
6.4
10
7
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.9
6.4
30
109
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
8.4
6.4
13
16
C02CA01
ATC
prazosin; oral
8.4
6.4
13
16
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
11.3
6.3
11
10
C10AA01
ATC
simvastatin; oral
1.8
6.3
155
1083
GD1UN
NOMESCO Finland
Lung circulation SPECT
18.4
6.3
9
5
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
+∞
6.3
6
*
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
+∞
6.3
6
*
N16.3*E72.0
ICD-10 Finland
Renal tubulo-interstitial disorders in cystinosis
+∞
6.3
6
*
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
+∞
6.3
6
*
7151
FHL
Kidney transplantation
+∞
6.3
6
*
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
+∞
6.3
6
*
FM1JR
NOMESCO Finland
Heart, extensive metabolic PET with CT
+∞
6.3
6
*
G05.8*M32.1
ICD-10 Finland
Encephalitis in systemic lupus erythematosus
+∞
6.3
6
*
58199
ICD-8 Finland
Nephrotic syndrome
+∞
6.3
6
*
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
27.2
6.3
8
*
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.7
6.1
19
53
TQW11
NOMESCO Finland
Vacuum treatment of wound
6.2
6.1
15
25
J05AB01
ATC
aciclovir; systemic
1.9
6.1
82
475
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
208
148
33.04
251.00
9.9
1.8
131.20
62.88
ng/l
9.96
192
132
251
286
28.29
232.79
21.1
3.1
1.13
0.98
mmol/l
10.64
245
263
175
344
9.15
96.23
7.4
1.8
22.46
23.93
%
0.71
154
293
180
397
8.25
87.81
7.2
1.8
11.47
13.87
umol/l
4.74
175
367
132
215
9.24
84.51
13.9
2.2
0.65
2.31
mmol/l
5.23
109
179
70
45
19.18
83.49
9.9
6.6
340.25
219.29
iu/ml
—
16
7
81
69
14.96
82.86
9.1
4.1
90.36
29.42
mg/l
0.53
59
56
81
69
14.96
82.86
9.1
4.1
563.80
41.74
mg/l
0.64
58
56
223
712
6.85
71.46
6.5
2.5
409.22
7509.74
umol/l
3.26
209
611
260
956
7.63
71.34
10.9
2.6
—
—
—
0
0
81
94
10.90
66.95
2.9
1.7
1.61
1.41
g/l
0.97
73
82
303
1353
10.06
65.48
37.3
5.4
1.22
1.21
mmol/l
0.47
269
1147
112
210
7.36
61.51
5.7
2.4
63.89
66.81
g/l
2.97
105
193
275
1182
7.13
59.75
16.7
4.3
34.45
35.80
g/l
3.62
268
1102
282
1245
7.44
59.26
28.4
4.8
1.23
1.21
mmol/l
2.74
274
1125
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
64
63
12.20
59.06
3.3
2.3
0.23
0.32
u/ml
1.05
27
38
263
1100
6.55
58.54
4.4
2.1
79.88
77.61
nmol/l
0.30
254
969
127
286
6.39
57.68
3.6
2.3
1.83
1.81
%
0.06
121
252
158
437
5.76
57.13
5.3
3.0
0.81
0.82
mmol/l
0.23
153
414
226
860
5.57
55.40
9.8
3.5
35.73
6.32
mg/mmol
3.65
205
512
223
863
5.34
52.86
8.6
2.8
6.26
7.96
mmol/l
8.75
216
692
52
44
13.70
52.64
2.0
1.3
99.29
119.18
u/ml
0.92
14
11
214
816
5.16
51.27
9.5
2.7
16.91
136.41
e6/l
0.85
197
620
200
743
4.93
48.99
8.9
2.6
0.26
0.38
e6/l
0.35
180
549
84
147
7.20
48.53
7.5
2.6
0.52
1.99
mmol/l
2.99
62
110
87
161
6.85
47.57
7.8
2.5
4.89
5.15
kpa
2.95
82
155
51
51
11.53
46.23
1.7
1.2
—
—
—
0
0
49
50
11.23
43.75
1.8
1.2
222.11
341.66
u/ml
0.99
37
29
139
455
4.40
38.54
6.5
2.4
0.55
0.79
e6/l
0.94
96
264
208
922
4.08
37.30
7.7
3.2
2.34
2.35
mmol/l
0.54
196
809
54
78
8.00
36.70
1.5
1.6
226.67
166.67
titre
—
6
6
236
1152
4.20
36.53
6.9
2.5
192.32
124.74
ug/l
5.00
223
1046
132
433
4.28
36.19
7.1
2.6
1.86
1.84
e6/l
0.01
90
245
73
147
6.01
36.11
9.5
5.9
23.44
24.91
mmol/l
2.28
73
147
78
172
5.54
34.91
2.7
1.5
—
—
—
0
0
125
410
4.18
34.00
2.9
1.7
—
—
—
0
0
44
57
8.68
32.64
2.3
1.7
—
—
—
0
0
44
60
8.24
31.27
2.3
1.7
—
—
—
0
0
51
87
6.69
29.60
6.4
2.4
0.80
1.06
g/l
0.20
42
79
56
106
6.10
29.30
5.2
2.0
—
—
—
0
0
274
1637
4.07
28.25
21.1
8.8
4.48
4.04
e9/l
1.80
257
1442
35
41
9.37
27.99
2.5
1.8
—
—
—
0
0
35
41
9.37
27.99
2.5
1.8
—
—
—
0
0
154
652
3.43
27.66
2.6
2.0
3.30
3.08
mg/l
0.39
137
552
94
288
4.09
27.51
2.7
1.6
—
—
—
0
0
239
1346
3.43
26.20
23.2
13.8
1.34
1.26
inr
0.54
65
397
36
50
7.91
25.07
4.0
2.1
16.86
16.32
%
0.22
26
20
34
45
8.26
24.64
1.1
1.2
—
—
—
0
0
41
69
6.60
23.99
1.7
1.2
—
—
—
0
0
32
41
8.49
23.79
2.2
1.8
—
—
—
0
0
278
1792
3.65
22.93
9.5
3.7
347.86
234.45
e6/l
—
7
29
227
1306
3.09
22.68
8.0
3.2
0.00
0.00
estimate
-0.00
50
272
42
78
5.98
22.24
1.9
1.2
—
—
—
0
0
87
290
3.66
22.16
3.1
1.7
—
—
—
0
0
247
1502
3.18
22.12
10.2
6.2
10.06
11.47
umol/l
2.08
239
1423
227
1323
3.03
21.84
8.0
3.3
0.00
0.01
estimate
0.50
46
246
225
1308
3.01
21.69
11.7
4.4
0.00
0.00
estimate
0.50
48
258
33
20
18.08
21.41
1.2
1.1
—
—
—
0
0
29
38
8.23
21.13
1.5
1.2
—
—
—
0
0
20
0
+∞
21.05
4.0
0.0
—
—
—
0
0
309
2193
4.42
20.68
21.6
7.3
80.35
77.53
u/l
0.48
300
2038
30
43
7.54
20.25
1.9
1.5
—
—
—
0
0
55
142
4.41
19.89
2.0
1.6
—
—
—
0
0
33
54
6.64
19.75
3.6
1.9
129.69
131.11
g/l
0.09
26
36
26
33
8.43
19.40
2.2
1.6
—
—
—
0
0
165
853
2.76
19.21
4.4
2.8
3591.57
974.28
ng/l
6.62
152
718
257
1672
3.01
18.98
13.5
4.3
6.72
6.64
mmol/l
0.27
247
1561
29
18
17.44
18.67
1.6
1.8
—
—
—
0
0
79
277
3.39
18.36
5.3
2.9
—
—
—
0
0
196
1128
2.67
18.10
2.4
1.9
102.27
97.28
pmol/l
0.66
111
563
90
348
3.13
17.75
12.3
6.3
102.96
104.40
mmol/l
1.71
90
348
28
43
6.99
17.74
15.1
1.3
70.77
65.40
%
0.57
28
43
34
65
5.68
17.39
2.4
1.4
—
—
—
0
0
32
58
5.97
17.29
1.4
1.7
—
—
—
0
0
16
0
+∞
16.80
13.7
0.0
4.99
—
mmol/l
—
16
0
136
688
2.59
15.90
3.6
2.3
—
—
—
0
0
107
483
2.75
15.71
2.0
1.7
1158.01
1156.13
nmol/l
0.01
90
360
24
37
6.89
15.12
2.0
1.5
—
—
—
0
0
289
2120
3.06
15.02
10.1
3.9
20.08
11.09
mm/h
10.99
281
1927
23
35
6.96
14.65
1.6
1.5
—
—
—
0
0
49
145
3.77
14.59
1.7
1.3
—
—
—
0
0
29
57
5.46
14.37
9.8
2.6
4.86
5.12
kpa
1.22
29
57
24
19
13.46
14.11
1.5
1.2
—
—
—
0
0
25
22
12.14
14.03
1.2
1.1
—
—
—
0
0
40
107
4.09
13.68
2.8
2.0
5.98
3.77
ug/l
0.16
40
96
32
72
4.79
13.61
4.8
2.3
293.59
105.07
ug/min
0.91
27
39
26
27
10.31
13.46
2.7
1.7
—
—
—
0
0
26
27
10.31
13.46
2.7
1.7
—
—
—
0
0
36
90
4.34
13.45
4.2
1.8
—
—
—
0
0
127
664
2.43
13.43
2.0
1.5
20.68
20.36
nmol/l
0.06
121
550
23
39
6.24
13.23
1.1
1.1
—
—
—
0
0
156
900
2.32
13.10
4.8
2.4
60.86
61.94
u/l
0.07
149
830
60
217
3.13
13.01
5.4
2.8
33.42
70.23
ml/min/173m2
13.77
40
86
205
1331
2.30
12.93
4.3
2.5
—
—
—
0
0
42
123
3.74
12.65
12.5
2.0
0.60
0.66
%
0.62
42
123
156
914
2.27
12.49
5.8
3.4
29.48
30.87
u/l
0.25
149
869
73
312
2.69
11.61
8.5
7.2
-0.07
1.28
mmol/l
1.01
60
260
24
30
8.50
11.28
1.7
1.6
—
—
—
0
0
23
27
9.03
11.21
2.2
2.0
—
—
—
0
0
22
24
9.70
11.17
2.3
2.1
—
—
—
0
0
112
595
2.30
11.09
3.0
1.6
1.41
1.10
mg/l
0.72
92
452
143
847
2.16
10.77
2.3
2.1
117.02
249.12
u/l
1.04
137
793
22
29
8.02
10.06
1.5
1.6
—
—
—
0
0
32
91
3.77
10.03
3.7
2.9
—
—
—
0
0
45
161
3.06
9.87
3.2
3.4
4.13
4.62
pmol/l
1.99
39
141
60
253
2.65
9.72
4.8
2.4
36.94
33.01
u/l
0.38
52
214
21
44
5.01
9.66
4.5
3.8
57.95
56.32
%
0.19
21
44
20
42
4.99
9.18
3.4
3.4
3.72
4.39
e9/l
0.62
20
42
68
315
2.44
9.03
6.7
3.0
7.86
7.46
umol/l
0.10
62
281
19
24
8.30
8.97
2.1
1.9
—
—
—
0
0
98
540
2.13
8.58
6.1
3.4
438.79
364.12
ng/l
0.12
90
416
23
58
4.17
8.47
1.2
1.3
78.67
20.07
u/ml
—
6
7
26
72
3.82
8.45
1.5
1.3
9.20
2.59
u/ml
—
5
11
20
46
4.55
8.26
1.4
1.3
—
—
—
0
0
20
46
4.55
8.26
1.4
1.3
—
—
—
0
0
24
64
3.95
8.22
1.3
1.2
—
—
—
0
0
31
99
3.34
8.17
2.4
1.8
—
—
—
0
0
26
74
3.71
8.14
1.5
1.3
3.83
2.71
u/ml
—
6
12
23
63
3.84
7.59
1.2
1.4
—
—
—
0
0
20
50
4.18
7.45
1.1
1.1
14.47
48.93
u/l
0.75
20
44
16
22
7.56
7.27
2.6
1.9
—
—
—
0
0
16
22
7.56
7.27
2.6
1.9
—
—
—
0
0
16
22
7.56
7.27
2.6
1.9
—
—
—
0
0
28
93
3.19
6.94
1.9
1.7
—
—
—
0
0
13
14
9.59
6.84
3.8
2.9
3423.62
834.50
u/ml
0.53
13
14
326
2866
2.93
6.76
51.1
12.5
17.13
22.72
mg/l
4.17
302
2218
160
1119
1.79
6.56
5.6
3.5
99.03
36.24
ng/l
0.68
131
805
311
2686
2.39
6.49
9.9
5.7
41.55
39.76
mmol/mol
1.92
303
2493
89
523
1.94
6.33
4.0
3.0
2.48
2.45
mmol/l
1.62
79
464
26
89
3.08
6.14
1.8
1.5
0.02
0.22
iu/ml
—
6
14
10
8
12.82
6.12
1.3
1.3
—
—
—
0
0
17
34
5.20
5.95
2.1
1.7
89.99
89.51
%
0.10
17
34
9
6
15.34
5.93
1.1
1.0
1600.00
1603.00
miu/ml
—
9
6
147
1026
1.74
5.91
8.5
3.4
—
—
—
0
0
14
24
6.03
5.58
3.4
1.7
—
—
—
0
0
15
29
5.35
5.45
1.9
2.1
33.33
33.31
pg
0.01
15
29
25
90
2.91
5.43
1.5
1.2
—
—
—
0
0
19
58
3.41
5.38
1.9
1.4
20073.71
31647.44
e6/l
0.42
14
43
91
566
1.82
5.34
1.6
1.8
442.57
441.96
pmol/l
0.01
81
463
16
35
4.74
5.24
1.7
1.2
6.00
1.27
u/ml
—
8
11
5
0
+∞
5.22
5.2
0.0
—
—
—
0
0
9
9
10.22
5.05
1.8
2.2
—
—
—
0
0
9
9
10.22
5.05
1.8
2.2
—
—
—
0
0
16
37
4.48
5.00
1.7
1.2
3.90
9.21
u/ml
—
10
14
14
28
5.16
4.99
20.2
9.0
6.95
6.70
mmol/l
0.11
14
21
13
24
5.58
4.96
2.5
3.1
35.50
39.58
%
—
6
12
24
90
2.79
4.85
1.5
1.2
—
—
—
0
0
9
10
9.20
4.81
1.8
2.1
—
—
—
0
0
10
14
7.32
4.68
1.7
1.9
—
—
—
0
0
10
14
7.32
4.68
1.7
1.9
—
—
—
0
0
19
64
3.08
4.63
1.5
1.1
—
—
—
0
0
18
59
3.16
4.58
1.5
1.5
—
—
—
0
0
326
2961
2.42
4.57
59.5
14.5
139.51
139.76
mmol/l
1.00
320
2874
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
8
8
10.20
4.54
10.8
2.5
142.00
122.50
%
—
8
8
10
15
6.83
4.50
1.1
1.9
—
—
—
0
0
10
15
6.83
4.50
1.1
1.9
—
—
—
0
0
50
270
1.99
4.47
2.5
2.0
0.24
0.22
g/l
0.95
45
247
326
2966
2.39
4.46
62.1
14.6
4.07
3.97
mmol/l
6.27
319
2874
252
2119
1.67
4.45
5.1
3.8
15.01
14.86
pmol/l
0.38
245
1891
22
84
2.73
4.32
2.0
1.6
—
—
—
0
0
103
701
1.66
4.30
8.9
3.5
0.00
0.00
estimate
0.50
41
248
7
6
11.87
4.29
1.0
1.5
—
—
—
0
0
13
30
4.46
4.17
1.7
1.4
—
—
—
0
0
10
17
6.02
4.16
1.0
1.3
—
—
—
0
0
7
7
10.17
4.02
2.9
1.0
76.43
100.29
%
—
7
7
11
23
4.90
3.90
2.8
2.0
—
—
—
0
0
9
16
5.74
3.68
2.3
2.9
—
—
—
0
0
9
17
5.40
3.53
1.6
1.2
—
—
—
0
0
8
13
6.27
3.52
1.1
1.0
—
—
—
0
0
8
14
5.82
3.36
1.0
1.4
—
—
—
0
0
13
38
3.51
3.35
1.0
1.1
—
—
—
0
0
10
23
4.44
3.33
1.3
1.2
—
—
—
0
0
10
23
4.44
3.33
1.3
1.2
—
—
—
0
0
10
23
4.44
3.33
1.3
1.2
—
—
—
0
0
10
23
4.44
3.33
1.3
1.2
—
—
—
0
0
10
23
4.44
3.33
1.3
1.2
—
—
—
0
0
11
29
3.88
3.21
1.5
1.2
127464.00
38495.12
e6/l
—
5
17
8
15
5.43
3.21
1.0
1.3
—
—
—
0
0
7
11
6.47
3.20
1.9
2.0
92.29
59.06
ug/l
—
7
11
9
20
4.59
3.13
1.2
1.4
—
—
—
0
0
223
1896
1.48
3.11
5.4
3.1
59.28
47.74
u/l
1.08
208
1749
7
13
5.47
2.88
1.9
2.2
111.86
100.54
%
—
7
13
6
9
6.76
2.88
1.3
1.1
—
—
—
0
0
5
6
8.43
2.76
1.8
2.3
33743.20
29950.83
ug/l
—
5
6
7
14
5.08
2.74
1.4
1.0
—
—
—
0
0
6
10
6.08
2.71
1.8
1.4
—
—
—
0
0
10
30
3.40
2.62
1.1
1.2
—
—
—
0
0
201
1708
1.41
2.59
3.8
2.9
—
—
—
0
0
8
20
4.07
2.58
1.4
1.5
—
—
—
0
0
5
7
7.23
2.55
1.0
4.9
243.00
204.57
u/l
—
5
7
300
2756
1.61
2.55
43.4
11.9
51.80
82.32
ml/min/173m2
45.32
279
2238
6
11
5.53
2.55
1.0
1.2
85.17
60.73
u/l
—
6
11
327
3077
1.92
2.50
28.4
10.1
23.78
26.67
u/l
3.48
322
2953
16
70
2.35
2.45
1.4
1.4
—
—
—
0
0
15
64
2.40
2.42
1.0
1.3
—
—
—
0
0
7
17
4.18
2.37
1.0
1.4
—
—
—
0
0
7
17
4.18
2.37
1.0
1.4
—
—
—
0
0
101
779
1.42
2.21
2.1
1.6
1.50
1.38
mmol/l
0.67
93
639
15
67
2.29
2.21
1.2
1.1
—
—
—
0
0
8
25
3.25
2.10
1.0
1.2
—
—
—
0
0
8
26
3.12
2.02
1.0
1.2
—
—
—
0
0
26
150
1.79
1.97
1.5
1.3
—
—
—
0
0
5
11
4.59
1.94
1.6
1.4
—
—
—
0
0
5
11
4.59
1.94
1.0
1.2
34.60
16.91
u/l
—
5
11
5
11
4.59
1.94
2.2
2.5
—
—
—
0
0
7
22
3.22
1.89
6.6
3.4
—
—
—
0
0
7
22
3.22
1.89
1.0
1.0
—
—
—
0
0
8
28
2.90
1.87
1.3
1.0
—
—
—
0
0
37
240
1.61
1.85
2.5
2.5
18.59
6.85
ug/l
0.44
32
208
76
574
1.41
1.85
7.4
3.4
1.02
1.02
kg/l
0.24
11
91
283
2616
1.42
1.85
6.1
4.5
2.25
2.38
mu/l
0.11
271
2352
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
17
3.57
1.84
1.5
1.1
—
—
—
0
0
6
17
3.57
1.84
1.2
1.1
1.88
1.77
mmol/l
—
6
17
306
2872
1.51
1.83
6.5
4.5
4.45
4.64
mmol/l
2.40
300
2647
7
23
3.08
1.81
1.0
1.3
—
—
—
0
0
6
18
3.37
1.75
1.8
1.1
—
—
—
0
0
5
13
3.88
1.72
1.2
1.0
—
—
—
0
0
6
19
3.19
1.67
1.5
1.2
94066.67
45647.50
e6/l
—
6
12
295
2762
1.43
1.65
6.0
4.0
1.57
1.27
mmol/l
7.70
286
2508
303
2851
1.46
1.65
6.6
4.4
1.35
1.47
mmol/l
5.20
296
2604
10
42
2.42
1.63
1.1
1.1
—
—
—
0
0
10
43
2.36
1.60
1.1
1.4
—
—
—
0
0
10
44
2.31
1.57
1.2
1.4
—
—
—
0
0
10
44
2.31
1.57
1.2
1.4
—
—
—
0
0
10
44
2.31
1.57
1.2
1.4
—
—
—
0
0
10
44
2.31
1.57
1.2
1.4
—
—
—
0
0
13
65
2.04
1.50
1.3
1.4
—
—
—
0
0
10
45
2.26
1.47
1.2
1.4
—
—
—
0
0
5
16
3.15
1.44
1.0
1.4
—
—
—
0
0
5
16
3.15
1.44
1.0
1.4
—
—
—
0
0
15
256
0.57
1.34
1.8
1.7
—
—
—
0
0
0
39
0.00
1.34
0.0
1.4
—
7.52
—
0
34
5
19
2.65
1.22
1.4
1.0
—
—
—
0
0
6
26
2.33
1.19
1.2
1.2
—
—
—
0
0
76
621
1.29
1.11
1.3
1.2
0.66
1.00
u/ml
1.02
14
184
7
32
2.21
1.08
1.0
1.4
—
—
—
0
0
7
34
2.08
1.03
1.1
1.0
—
—
—
0
0
9
48
1.90
1.01
1.9
1.9
—
—
—
0
0
7
35
2.02
1.00
1.3
1.0
—
—
—
0
0
305
2925
1.33
1.00
6.9
5.0
2.54
2.75
mmol/l
3.69
297
2676
329
3194
1.48
0.99
68.2
19.0
232.81
244.08
e9/l
2.24
323
3100
12
69
1.77
0.97
1.0
1.3
—
293.15
—
0
32
329
3196
1.47
0.96
69.2
19.1
38.08
40.53
%
8.47
303
2992
329
3197
1.46
0.94
68.2
19.0
4.23
4.53
e12/l
13.94
322
3092
329
3198
1.46
0.93
68.5
19.1
126.37
136.93
g/l
19.64
323
3142
57
468
1.26
0.82
1.4
1.4
—
—
—
0
0
24
173
1.42
0.81
1.0
1.3
123.72
159.80
iu/ml
—
6
72
6
33
1.83
0.79
1.3
1.0
—
—
—
0
0
5
26
1.94
0.71
1.2
1.5
—
—
—
0
0
7
42
1.68
0.69
5.7
2.6
103.71
105.48
mmol/l
—
7
42
19
256
0.73
0.64
2.3
2.2
—
—
—
0
0
9
137
0.65
0.62
1.0
1.0
—
—
—
0
0
24
184
1.33
0.59
1.4
1.3
—
48.65
—
0
11
17
230
0.73
0.59
1.9
2.0
—
—
—
0
0
7
114
0.61
0.59
1.4
2.0
—
—
—
0
0
5
88
0.56
0.57
1.4
1.9
—
—
—
0
0
6
37
1.63
0.56
1.2
1.1
—
—
—
0
0
12
82
1.48
0.55
5.0
4.3
3.93
3.93
mmol/l
0.02
12
82
6
38
1.59
0.54
1.2
1.1
1.43
1.50
g/l
—
6
32
290
2818
1.17
0.49
7.5
4.6
6.06
5.96
mmol/l
0.56
266
2560
6
94
0.63
0.42
1.2
1.9
—
—
—
0
0
12
89
1.36
0.38
1.3
1.3
24.39
25.58
iu/l
0.05
12
76
37
325
1.15
0.31
1.5
1.7
1.45
1.50
%
0.23
31
286
53
478
1.13
0.31
1.2
1.3
93.79
30.51
iu/ml
0.69
17
156
16
129
1.25
0.31
2.6
3.7
1852.12
1997.28
u/ml
0.02
16
113
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
197.22
—
0
12
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
120
1152
1.06
0.19
4.5
5.0
2.23
2.56
ug/l
0.30
110
1017
5
69
0.72
0.17
2.2
1.5
—
—
—
0
0
9
83
1.09
0.14
2.1
1.5
245.00
260.96
mu/l
—
9
78
11
93
1.19
0.14
1.2
1.7
38.73
38.88
nmol/l
0.01
11
88
34
367
0.92
0.14
2.0
1.5
—
—
—
0
0
5
44
1.14
0.10
1.0
1.5
—
—
—
0
0
33
350
0.94
0.09
19.8
6.5
—
—
—
0
0
66
678
0.97
0.06
2.6
3.0
0.97
0.70
ug/l
1.03
43
441
45
464
0.97
0.05
1.2
1.3
8.88
9.35
u/ml
—
10
189
32
309
1.04
0.04
2.3
4.4
3.20
40.67
ug/l
0.88
26
265
92
917
1.00
0.00
4.2
4.4
27.33
21.10
%
2.56
47
407
8
83
0.96
0.00
1.3
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1.17
—
0
5
8
82
0.98
-0.00
1.1
1.1
—
10.79
—
0
10
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_RENALTUBULOINOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RENALTUBULOINOTH | 2.925 [2.31, 3.71] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.263 |
During the follow-up period (1.1.1998 — 31.12.2019), 286 out of 748 females with N14_RENALTUBULOINOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RENALTUBULOINOTH | 2.812 [2.18, 3.63] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 319 out of 809 males with N14_RENALTUBULOINOTH died.
Mortality risk
Mortality risk for people of age
years, who have N14_RENALTUBULOINOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.25% | 0.476% |
| 5 | 1.735% | 2.944% |
| 10 | 4.3% | 7.322% |
| 15 | 8.306% | 13.33% |
| 20 | 14.035% | 21.922% |
Relationships between endpoints
↥Index endpoint: N14_RENALTUBULOINOTH – Renal tubulo-interstitial disorders in diseases classified elsewhere
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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