Behcet's syndrome: Bechet disease (BD) is a chronic, relapsing, multisystemic vasculitis characterized by mucocutaneous lesions, as well as articular, vascular, ocular and central nervous system manifestations.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
109 |
4. Check minimum number of eventsNone |
109 |
5. Include endpointsNone |
109 |
6. Filter based on genotype QC (FinnGen only) |
109 |
Control definitions (FinnGen only)
- Control exclude
- M13_SYSTCONNECT
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M35
- Name in latin
- Morbus Behçet
Similar endpoints
↥List of similar endpoints to
Behçet disease
based on the number of shared cases.
Similar with more cases:
- Other systemic involvement of connective tissue (FG)
- Other systemic involvement of connective tissue
- Systemic connective tissue disorders
- Finngen Rheumatological endpoints
- Autoimmune diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 612 | 415 | 187 |
| Only index persons | 535 | 378 | 157 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 53.29 | 53.02 | 54.96 |
| Only index persons | 51.23 | 50.44 | 53.11 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 109 | 82 | 27 |
| Unadjusted period prevalence (%) | 0.02 | 0.03 | 0.01 |
| Median age at first event (years) | 46.74 | 44.78 | 52.72 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 103
- Matched controls
- 1027
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M35.2
ICD-10 Finland
Behçet disease
+∞
137.8
99
*
L04AX01
ATC
azathioprine; systemic
43.2
34.1
42
16
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
17.1
27.6
47
48
H02AB06
ATC
prednisolone; systemic
11.0
24.8
85
309
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
17.2
24.7
41
38
K12.00
ICD-10 Finland
Recurrent oral aphthae
52.0
18.1
21
5
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
6.3
17.0
62
198
M35.3
ICD-10 Finland
Polymyalgia rheumatica
35.8
14.4
18
6
N77.8*M35.2
ICD-10 Finland
Ulceration of vulva in Behçet's disease
+∞
13.9
13
*
H02AB07
ATC
prednisone; oral
6.6
12.5
35
74
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
11.8
12.0
22
23
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
9.7
11.7
24
31
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
+∞
11.7
11
*
P01BA02
ATC
hydroxychloroquine; oral
7.9
10.0
23
36
N76.6
ICD-10 Finland
Ulceration of vulva
33.6
9.6
12
*
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
9.5
9
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
12.4
9.2
16
15
K12.10
ICD-10 Finland
Stomatitis NOS
54.8
8.8
10
*
L04AA01
ATC
[U] ciclosporin; systemic
54.8
8.8
10
*
L04AD01
ATC
ciclosporin; systemic
30.4
8.7
11
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
+∞
8.4
8
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
8.1
8.2
18
26
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
8.2
56
265
M05BA04
ATC
alendronic acid; oral
6.5
8.1
21
39
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.7
7.9
41
157
H20.1
ICD-10 Finland
Chronic iridocyclitis
48.8
7.8
9
*
M13.9
ICD-10 Finland
Arthritis, unspecified
7.6
7.8
18
28
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
20.3
7.8
11
6
ZX120
NOMESCO Finland
Intravenous
5.9
7.5
21
43
R50.9
ICD-10 Finland
Fever, unspecified
4.2
7.4
30
92
M35.1
ICD-10 Finland
Other overlap syndromes
+∞
7.4
7
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
12.2
7.0
12
11
UJF30
NOMESCO Finland
Ileoscopy through colon
5.3
7.0
21
47
H04.10
ICD-10 Finland
Dry eye syndrome
5.1
7.0
22
52
R1250
NOMESCO Finland
Evaluation of functional capability
18.2
6.9
10
6
N02AX02
ATC
tramadol; systemic, rectal
3.1
6.9
53
265
J05AB11
ATC
valaciclovir; oral
4.5
6.8
25
69
UJF92
NOMESCO Finland
Capsular endoscopy
24.4
6.8
9
*
A07EC01
ATC
sulfasalazine; oral, rectal
5.7
6.8
19
39
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
6.3
6.7
17
31
M35.7
ICD-10 Finland
Hypermobility syndrome
74.3
6.5
7
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.9
6.5
21
51
M05BA07
ATC
risedronic acid; oral
10.3
6.5
12
13
L88
ICPC
Rheumatoid/seropositive arthritis
11.0
6.2
11
11
J01FF01
ATC
clindamycin; systemic
3.1
6.1
39
169
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
19
11
20.71
23.46
1.3
1.4
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
45
95
7.36
22.55
2.3
1.4
titre
933.3
460.0
0.58
12
22
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
17
13
15.31
18.09
1.1
1.0
—
—
—
0
0
(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence
17
18
11.00
14.72
1.5
1.4
—
—
—
0
0
(3009445) Proteinase 3 Ab [Units/volume] in Serum
20
29
8.22
13.64
1.2
1.0
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
17
20
9.89
13.63
2.4
1.5
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
63
260
4.37
13.21
21.4
4.2
—
—
—
0
0
(4062490)
17
7
28.41
12.92
2.6
1.3
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
29
66
5.62
12.83
1.4
1.4
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
15
5
34.36
12.00
1.4
1.4
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
15
5
34.36
12.00
1.4
1.4
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
15
5
34.36
12.00
1.4
1.4
—
—
—
0
0
(3022096) Basophils/100 leukocytes in Blood
73
358
4.15
11.52
23.2
4.9
%
0.8
0.7
0.83
73
331
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
15
6
28.64
11.49
1.4
1.3
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
15
6
28.64
11.49
1.4
1.3
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
15
6
28.64
11.49
1.4
1.3
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
75
382
4.09
11.03
21.3
4.7
%
56.7
57.1
0.08
75
360
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
14
17
9.30
10.86
3.6
2.4
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
32
91
4.56
10.76
2.3
1.4
—
—
—
0
0
(3006504) Eosinophils/100 leukocytes in Blood
73
370
3.95
10.70
23.1
4.8
%
2.6
2.8
0.35
73
344
(3007164) IgA [Mass/volume] in Serum or Plasma
49
191
3.84
10.68
3.0
1.4
g/l
2.3
2.1
0.26
40
112
(3002030) Lymphocytes/100 leukocytes in Blood
75
390
3.96
10.52
23.1
4.9
%
29.4
28.6
0.25
75
366
(3019069) Monocytes/100 leukocytes in Blood
73
375
3.87
10.38
23.7
5.3
%
8.5
8.2
0.31
73
353
(3004789) Transferrin [Mass/volume] in Serum or Plasma
32
99
4.16
9.55
1.8
1.8
g/l
2.5
2.4
0.44
27
87
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
12
14
9.51
9.53
1.2
1.2
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
34
111
4.00
9.41
2.9
1.7
ug/g
82.5
83.1
0.01
29
82
(40758558) Short blood count panel - Blood
49
206
3.50
9.29
12.6
7.6
—
—
—
0
0
(3005895) Myoglobin [Mass/volume] in Serum or Plasma
11
12
10.08
9.13
3.4
2.0
ug/l
74.4
271.1
1.28
11
12
(3024561) Albumin [Mass/volume] in Serum or Plasma
62
313
3.27
8.54
5.1
4.2
g/l
35.5
36.2
0.41
57
297
(3017143) Hepatitis C virus Ab [Presence] in Serum
34
119
3.70
8.44
1.4
1.4
—
—
—
0
0
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
65
341
3.24
8.33
3.2
2.1
nmol/l
79.5
75.1
0.55
58
308
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
10
11
9.91
8.21
1.2
1.4
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
10
11
9.91
8.21
1.1
1.0
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
11
14
8.63
8.14
1.5
1.2
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
68
373
3.19
7.95
12.9
7.6
mmol/l
1.2
1.2
0.23
57
317
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
10
12
9.07
7.70
1.2
1.2
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
12
19
6.97
7.41
1.8
1.2
—
—
—
0
0
(46235355) HIV 1 and 2 tests - Meaningful Use set
45
203
3.07
7.29
1.8
1.9
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
19
49
4.49
7.06
2.7
1.5
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
10
14
7.76
6.82
1.4
1.1
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
54
280
2.84
6.66
5.3
2.6
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
17
42
4.61
6.64
2.3
1.4
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
40
179
2.95
6.45
1.6
1.6
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
17
43
4.50
6.44
1.5
1.2
—
—
—
0
0
(3023368) Bacteria identified in Blood by Culture
41
187
2.91
6.38
6.4
4.3
—
—
—
0
0
(3001964) Herpes simplex virus Ag [Presence] in Specimen
6
0
+∞
6.30
1.8
0.0
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
14
32
4.87
5.96
2.5
1.4
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
62
363
2.64
5.80
21.9
7.5
e9/l
0.0
0.0
0.49
57
292
(3000494) Fungus identified in Specimen by Culture
27
102
3.19
5.78
3.6
1.6
—
—
—
0
0
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
13
29
4.95
5.68
1.2
1.4
—
—
—
0
0
(3002179) Metamyelocytes/100 leukocytes in Blood
18
53
3.87
5.59
10.9
4.1
%
0.3
0.6
—
7
10
(3025159) Blasts/100 leukocytes in Blood
18
53
3.87
5.59
11.3
3.9
%
0.0
0.8
—
8
11
(3021440) Promyelocytes/100 leukocytes in Blood
18
53
3.87
5.59
12.8
4.0
%
0.0
0.2
—
8
12
(3048929) Epstein Barr virus Ab [Presence] in Serum
12
26
5.06
5.40
1.9
1.2
—
—
—
0
0
(3017181) Myelocytes/100 leukocytes in Blood
19
61
3.56
5.21
12.6
3.7
%
0.0
0.7
—
8
16
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
8
7
12.20
4.86
1.3
1.3
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
12
29
4.53
4.76
1.4
1.3
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
84
602
2.72
4.75
8.8
3.7
—
—
—
0
0
(3018418) pH of Serum or Plasma
43
228
2.46
4.75
6.0
3.6
ph
7.4
7.4
—
9
41
(40768797) Stomach Pathology biopsy report
27
114
2.82
4.70
1.5
1.2
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
8
8
10.67
4.60
1.0
1.3
—
—
—
0
0
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
40
208
2.46
4.58
2.7
3.1
ng/l
533.2
973.8
0.99
30
170
(36304419) Bacteria [Presence] in Urine
43
232
2.41
4.54
4.0
2.3
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
36
181
2.48
4.41
6.0
3.4
—
—
—
0
0
(3000570) Elastase.pancreatic [Mass/mass] in Stool
10
22
4.90
4.40
1.1
1.5
ug/g
413.8
241.9
—
5
12
(3032080) INR in Blood by Coagulation assay
50
292
2.32
4.38
11.5
6.6
inr
1.2
1.2
0.11
12
93
(3020717) Zinc [Moles/volume] in Serum or Plasma
7
6
12.34
4.34
1.6
1.0
umol/l
11.3
13.5
—
7
6
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
36
183
2.44
4.30
2.9
1.9
mg/l
3.0
2.9
0.11
31
158
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
28
127
2.62
4.23
4.0
1.6
—
—
—
0
0
(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid
7
7
10.57
4.07
1.0
1.3
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
37
196
2.34
4.00
3.1
2.9
umol/l
321.0
4334.5
0.80
32
166
(3021601) Nitrite [Presence] in Urine by Test strip
63
418
2.20
3.92
8.4
4.4
estimate
0.0
0.0
0.00
13
83
(40768443) Skin Pathology biopsy report
12
34
3.84
3.89
1.9
1.1
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
63
421
2.18
3.82
6.3
3.2
estimate
0.0
0.0
0.00
13
82
(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum
6
5
12.58
3.81
1.0
1.2
—
—
—
0
0
(4306422)
8
12
7.09
3.74
1.0
1.2
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
12
35
3.73
3.74
1.8
3.3
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
62
417
2.13
3.64
6.3
3.1
estimate
0.0
0.0
0.00
12
84
(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay
9
17
5.66
3.59
2.1
3.2
g/l
4.0
3.9
—
9
17
(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid
6
6
10.48
3.54
1.0
1.3
—
—
—
0
0
(3019230) Fractional oxyhemoglobin in Venous blood
6
6
10.48
3.54
2.3
1.0
%
47.9
49.3
—
6
6
(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid
6
6
10.48
3.54
1.0
1.3
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
27
131
2.41
3.50
1.6
1.6
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
13
42
3.38
3.50
3.0
2.2
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
49
306
2.09
3.45
6.7
2.8
e6/l
15.2
46.7
1.74
41
208
(3044290) Cell count panel - Cerebral spinal fluid
7
10
7.39
3.42
1.0
1.3
—
—
—
0
0
(3029634) Reagin Ab [Titer] in Serum by VDRL
7
10
7.39
3.42
1.0
1.3
—
—
—
0
0
(3052851) Hemolysis interference index of Serum or Plasma
9
19
5.06
3.32
2.1
3.3
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
37
210
2.15
3.31
1.7
1.3
u/ml
0.6
1.8
—
10
50
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
29
150
2.27
3.25
1.4
1.2
iu/ml
11.6
37.4
—
7
50
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
11
34
3.49
3.15
1.5
1.1
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
25
123
2.34
3.13
3.9
2.2
e6/l
1.8
3.7
0.73
18
57
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
8
16
5.30
3.11
1.0
1.1
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
9
21
4.57
3.07
1.7
1.4
—
—
—
0
0
(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum
5
5
10.39
3.01
1.0
1.0
—
—
—
0
0
(3028679) Herpes simplex virus Ab [Presence] in Serum
5
5
10.39
3.01
1.8
1.0
—
—
—
0
0
(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis
8
17
4.99
2.98
2.1
4.3
g/l
0.0
0.0
—
8
17
(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis
8
17
4.99
2.98
2.1
4.3
g/l
0.0
0.0
—
8
17
(3009343) pH of Capillary blood
12
41
3.17
2.96
7.6
2.6
—
7.4
—
0
6
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
9
22
4.36
2.95
1.7
1.1
—
—
—
0
0
(3031040) Bacteria [#/volume] in Urine by Automated count
76
578
2.04
2.92
7.6
3.8
—
1167.7
—
0
7
(3026389) Candida sp identified in Specimen by Organism specific culture
6
9
6.98
2.90
1.0
1.2
—
—
—
0
0
(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis
8
18
4.71
2.85
2.1
4.2
g/l
0.0
0.0
—
8
18
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
19
86
2.46
2.84
2.8
1.5
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
20
93
2.41
2.82
7.4
7.1
—
—
—
0
0
(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection
5
6
8.65
2.77
1.6
2.0
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
5
6
8.65
2.77
1.2
1.2
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
5
6
8.65
2.77
1.8
1.0
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
5
6
8.65
2.77
1.0
1.3
—
—
—
0
0
(3047007) Chlamydophila sp Ab [Presence] in Serum
6
10
6.27
2.73
1.2
1.4
—
—
—
0
0
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
18
81
2.46
2.72
2.9
1.8
u/l
1413.0
28.4
0.47
13
66
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
24
124
2.20
2.67
2.8
3.2
ng/l
507.6
125.5
0.34
14
92
(3015377) Calcium [Moles/volume] in Serum or Plasma
42
268
1.92
2.65
3.0
3.3
mmol/l
2.3
2.4
0.61
35
241
(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum
7
15
4.91
2.64
1.3
1.3
—
—
—
0
0
(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method
9
25
3.83
2.64
2.9
2.3
%
95.1
93.7
—
9
25
(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay
8
20
4.23
2.62
1.6
1.4
—
—
—
0
0
(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay
8
20
4.23
2.62
1.6
1.4
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
33
195
1.99
2.59
2.5
1.7
mg/l
1.2
0.9
0.20
25
148
(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay
6
11
5.70
2.58
1.2
1.2
—
—
—
0
0
(4268621)
6
11
5.70
2.58
2.2
1.9
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
5
7
7.41
2.57
1.8
1.1
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
7
16
4.60
2.52
1.6
1.3
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
22
113
2.19
2.47
2.9
2.3
—
—
—
0
0
(3022313) Gas panel - Capillary blood
9
27
3.54
2.45
8.9
3.0
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
18
85
2.34
2.45
2.9
1.6
—
—
—
0
0
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
8
22
3.84
2.41
2.1
3.6
—
—
—
0
0
(3015736) pH of Urine
48
328
1.83
2.41
5.3
3.0
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
5
8
6.48
2.39
1.0
1.6
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
5
8
6.48
2.39
1.2
1.3
—
—
—
0
0
(3042631) Mycobacterium sp identified in Specimen
5
8
6.48
2.39
4.0
4.4
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
9
28
3.41
2.37
1.2
1.2
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
61
452
1.79
2.31
9.8
6.1
umol/l
9.2
9.8
0.67
56
425
(40761535) Cells panel - Urine sediment
14
61
2.49
2.25
7.9
3.6
—
—
—
0
0
(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
9
5.76
2.23
2.0
2.2
—
—
—
0
0
(3008898) HLA-B27 [Presence]
10
37
2.87
2.17
1.2
1.1
—
—
—
0
0
(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma
19
97
2.16
2.16
1.6
2.1
umol/l
4.2
6.0
0.77
13
79
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
46
319
1.76
2.14
4.4
3.5
ng/l
25.6
53.5
0.79
26
196
(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence
5
10
5.18
2.09
1.2
1.3
—
—
—
0
0
(3037756) Immunofixation for Serum or Plasma
5
10
5.18
2.09
1.2
1.7
—
—
—
0
0
(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma
13
57
2.45
2.07
2.5
4.8
pmol/l
4.1
4.5
0.73
13
51
(3024928) Oxygen saturation in Venous blood
6
15
4.17
2.07
2.8
3.5
—
—
—
0
0
(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay
6
15
4.17
2.07
1.3
1.1
—
0.9
—
0
6
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
6
15
4.17
2.07
1.0
1.1
—
—
—
0
0
(3022145) Colonoscopy Study observation
18
92
2.15
2.04
1.4
1.3
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
44
306
1.73
2.01
2.2
1.8
pmol/l
106.2
97.9
0.56
30
151
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
38
254
1.76
1.99
2.6
2.7
u/l
51.9
56.6
0.55
33
230
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
6
16
3.90
1.96
8.3
1.8
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
6
16
3.90
1.96
7.8
1.8
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
5
11
4.71
1.96
2.0
2.8
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
5
11
4.71
1.96
2.2
2.1
—
—
—
0
0
(3012544) pH of Venous blood
14
66
2.29
1.91
4.7
3.2
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
6
17
3.67
1.86
1.0
1.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
32
207
1.77
1.85
11.0
4.9
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
24
142
1.89
1.84
3.5
2.0
e6/l
0.4
0.9
1.16
18
75
(3019550) Sodium [Moles/volume] in Serum or Plasma
98
869
2.27
1.83
28.6
13.9
mmol/l
139.5
139.8
0.51
93
843
(3019150) Specific gravity of Urine by Refractometry
29
184
1.78
1.79
5.9
3.4
kg/l
1.0
1.0
—
7
23
(3002032) Base excess in Venous blood by calculation
13
62
2.25
1.73
5.0
2.9
mmol/l
2.4
2.8
0.15
13
50
(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination
5
13
3.98
1.73
1.0
1.4
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
99
887
2.27
1.70
34.2
11.7
mg/l
14.2
22.3
3.11
90
668
(3019225) pH of Specimen
15
77
2.10
1.69
10.7
4.5
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
6
19
3.28
1.68
5.8
2.5
e9/l
4.8
4.7
—
6
19
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
6
19
3.28
1.68
6.0
2.6
%
58.0
56.7
—
6
19
(3026008) Bacteria identified in Urine by Culture
36
248
1.67
1.65
3.9
2.6
—
—
—
0
0
(3044640) Blood type and Crossmatch panel - Blood
39
277
1.64
1.59
3.4
2.2
—
—
—
0
0
(3000991) Gas panel - Venous blood
12
58
2.20
1.56
23.4
9.5
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
10
45
2.35
1.51
2.4
3.0
g/l
126.0
130.1
—
10
45
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
31
210
1.67
1.50
2.2
1.6
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
9
38
2.49
1.49
27.1
5.0
mmol/l
26.1
26.2
—
9
38
(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood
9
38
2.49
1.49
2.3
2.5
%
1.3
1.3
—
9
38
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
15
81
1.99
1.49
1.7
1.8
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
7
28
2.60
1.48
1.3
1.1
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
7
28
2.60
1.48
1.3
1.1
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
7
28
2.60
1.48
1.3
1.1
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
53
412
1.56
1.46
3.9
4.4
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
44
328
1.57
1.45
6.3
3.2
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
23
145
1.74
1.44
2.0
1.7
nmol/l
831.9
1182.0
1.07
17
108
(3013512) EKG study
32
222
1.62
1.41
5.0
3.5
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
30
206
1.63
1.38
3.4
2.2
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
8
34
2.46
1.32
27.4
24.8
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
8
35
2.39
1.30
7.0
1.7
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
23
150
1.68
1.28
1.4
1.3
u/ml
40.3
9.5
—
6
62
(3029937) Albumin [Presence] in Urine by Test strip
32
230
1.55
1.21
7.8
3.4
estimate
0.0
0.0
0.00
13
82
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
10
50
2.10
1.21
1.0
1.0
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
8
39
2.13
1.18
1.3
1.4
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
14
81
1.84
1.15
3.2
3.2
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
22
314
0.62
1.14
2.2
2.8
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
12
66
1.92
1.14
1.6
1.8
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
7
31
2.34
1.12
2.1
1.5
—
—
—
0
0
(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma
8
41
2.03
1.11
2.5
1.5
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
5
21
2.44
1.10
1.2
2.0
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
5
21
2.44
1.10
1.0
1.1
—
—
—
0
0
(3022217) INR in Platelet poor plasma by Coagulation assay
14
83
1.79
1.07
21.7
27.1
—
1.4
—
0
15
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
90
817
1.58
1.00
23.9
10.7
ml/min/173m2
86.6
85.9
0.09
85
656
(4035726)
13
77
1.78
1.00
1.6
1.4
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
10
54
1.94
1.00
1.4
1.2
—
—
—
0
0
(3017044) Thyrotropin receptor Ab [Units/volume] in Serum
0
28
0.00
0.99
0.0
1.7
—
5.2
—
0
14
(3045414) Leukocytes [Presence] in Urine
7
36
2.01
0.99
1.9
1.8
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
32
240
1.47
0.98
5.3
2.7
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
6
30
2.06
0.88
1.2
1.6
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
25
186
1.45
0.79
1.5
1.4
—
—
—
0
0
(4010399)
9
54
1.73
0.77
2.6
1.4
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
5
24
2.13
0.75
1.4
2.2
—
—
—
0
0
(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma
12
76
1.65
0.75
1.4
4.4
ug/l
2.4
7.8
—
5
60
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
15
101
1.56
0.75
4.4
3.7
%
28.0
32.0
—
9
69
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
7
42
1.71
0.70
32.3
11.5
%
1.1
1.5
—
7
42
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
7
42
1.71
0.70
32.3
11.5
%
0.4
0.7
—
7
42
(3022621) pH of Urine by Test strip
8
49
1.68
0.64
4.9
2.1
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
12
80
1.56
0.63
1.9
1.1
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
32
261
1.32
0.59
1.4
1.5
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
6
37
1.66
0.56
1.8
3.1
—
—
—
0
0
(1001926) Buprenorphine [Presence] in Urine by Screen method
6
38
1.61
0.55
2.2
1.8
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
79
841
0.78
0.49
4.4
4.0
mmol/l
4.8
4.7
0.26
74
790
(40768804) Tissue Pathology biopsy report
42
364
1.25
0.48
2.5
2.0
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
7
48
1.49
0.48
2.1
1.7
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
7
48
1.49
0.48
2.1
1.7
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
7
48
1.49
0.48
2.1
1.7
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
7
49
1.46
0.47
2.1
1.7
—
—
—
0
0
(3011288) Drugs identified in Urine by Screen method
5
32
1.59
0.43
2.0
2.0
—
—
—
0
0
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
73
779
0.81
0.42
5.8
5.1
mmol/mol
38.2
39.2
0.41
73
737
(3002256) Pathology report gross observation
14
106
1.37
0.41
1.2
1.2
—
—
—
0
0
(3051387) C reactive protein [Mass/volume] in Capillary blood
0
16
0.00
0.41
0.0
4.5
—
29.9
—
0
9
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
81
854
0.80
0.40
4.6
4.5
mmol/l
2.7
2.8
0.56
76
797
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
9
68
1.35
0.39
1.2
1.5
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
13
100
1.34
0.35
1.8
1.8
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
6
46
1.32
0.33
2.3
1.7
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
96
931
1.26
0.27
24.0
11.3
—
—
—
0
0
(3000492) Spirometry study
9
74
1.24
0.26
2.8
1.3
—
—
—
0
0
(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum
5
37
1.37
0.24
1.2
1.3
—
274.5
—
0
20
(3027273) Bicarbonate [Moles/volume] in Venous blood
5
39
1.30
0.23
2.0
3.0
mmol/l
25.9
24.4
—
5
39
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
5
39
1.30
0.23
2.2
3.3
%
41.3
42.9
—
5
39
(21494755) Public health laboratory ask at order entry panel
8
103
0.76
0.22
1.3
1.3
—
—
—
0
0
(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma
5
42
1.20
0.22
1.4
1.6
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
67
637
1.13
0.21
4.4
3.4
—
—
—
0
0
(3005570) Glucose [Moles/volume] in Urine
0
10
0.00
0.21
0.0
3.1
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
(3039443) Prostate specific Ag panel - Serum or Plasma
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
14
118
1.21
0.20
1.3
1.7
%
1.3
1.4
0.18
14
101
(3009542) Hematocrit [Volume Fraction] of Blood
85
822
1.15
0.20
32.5
12.8
%
39.8
40.3
0.59
63
636
(3019060) Gas panel - Arterial blood
6
50
1.21
0.20
3.0
12.9
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
10
120
0.82
0.17
1.7
1.5
—
—
—
0
0
(3044889) 12 lead EKG panel
60
572
1.11
0.17
4.7
3.5
—
—
—
0
0
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
12
133
0.89
0.08
2.0
2.1
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
6
74
0.80
0.08
1.3
1.5
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
18
192
0.93
0.06
3.9
3.3
mg/l
143.4
56.9
—
10
122
(3020682) Albumin/Creatinine [Ratio] in Urine
19
202
0.93
0.06
5.6
3.9
mg/mmol
14.2
10.2
0.13
11
128
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
14
148
0.94
0.02
2.0
2.2
—
—
—
0
0
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
83
822
1.04
0.02
5.8
4.1
mmol/l
5.5
5.8
2.16
78
760
(40761536) Microorganisms panel - Urine sediment
8
81
0.99
0.00
10.1
2.6
—
—
—
0
0
(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
2.1
—
0
5
(3051611) Lipemic interference index of Serum or Plasma
0
9
0.00
0.00
0.0
2.6
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
9
95
0.94
0.00
1.3
1.7
—
—
—
0
0
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
4.8
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
(4024509)
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
5
0.00
0.00
0.0
4.8
—
—
—
0
0
(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3010838) Calcium [Moles/time] in 24 hour Urine
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(3019977) pH of Arterial blood
0
5
0.00
0.00
0.0
4.8
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint M13_BEHCET and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_BEHCET | 1.717 [1.24, 2.37] | 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.166 |
During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 370 females with M13_BEHCET died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have M13_BEHCET.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.128% | No data |
| 5 | 0.803% | No data |
| 10 | 2.061% | No data |
| 15 | 4.356% | No data |
| 20 | 7.527% | No data |
Relationships between endpoints
↥Index endpoint: M13_BEHCET – Behçet disease
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data