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Malignant neoplasm of gallbladder, including Hilmo

C3_GALLBLADDER_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C23&
  • Hospital discharge: ICD-9 1560
  • Hospital discharge: ICD-8 1560
  • Cause of death: ICD-10 C23&
  • Cause of death: ICD-9 1560
  • Cause of death: ICD-8 1560
  • Cancer registry: Topography ICD-O-3 C23
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

252

4. Check minimum number of events

None

252

5. Include endpoints

None

252

6. Filter based on genotype QC (FinnGen only)

245

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 245 150 95
Unadjusted period prevalence (%) 0.05 0.05 0.04
Median age at first event (years) 70.18 69.42 71.38

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
252
Matched controls
2520
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
+∞
317.6
233
*
H02AB02
ATC
dexamethasone; systemic
121.1
159.5
82
10
130
Kela drug reimbursment
Malignant tumour
+∞
147.9
127
*
Z51.5
ICD-10 Finland
Palliative care
32.1
121.2
86
40
8140/3-C23.9
ICD-O-3
Adenocarcinoma, NOS, of gallbladder
+∞
115.8
102
*
A03FA01
ATC
metoclopramide; systemic, rectal
14.8
106.8
138
190
WX302
NOMESCO Finland
Thoracal epidural anesthesy
43.0
99.4
62
19
A04AA01
ATC
ondansetron; systemic, rectal
31.1
84.1
58
24
A04AA02
ATC
granisetron; systemic, transdermal
+∞
77.1
70
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
71.3
65
*
L01BC06
ATC
capecitabine; oral
+∞
67.8
62
*
UJK02
NOMESCO Finland
ERCP
23.4
66.7
51
27
N02AA05
ATC
oxycodone; systemic
8.3
62.4
122
256
JKA20
NOMESCO Finland
Cholecystectomy
20.1
55.3
45
27
JN4BD
NOMESCO Finland
Extensive body CT
12.7
53.4
58
58
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
166.8
52.1
53
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
12.6
49.3
53
52
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
13.9
48.9
49
43
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
21.1
48.3
38
21
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
9.4
47.4
66
92
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
45.2
42
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
16.5
41.6
37
26
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
63.8
41.2
47
9
JN4AD
NOMESCO Finland
Body CT examination
9.8
40.8
53
67
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
236.5
40.1
40
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
101.2
32.7
35
*
K83.0
ICD-10 Finland
Cholangitis
61.6
32.3
37
7
8000/3-C23.9
ICD-O-3
Neoplasm, malignant of gallbladder
+∞
30.9
29
*
WZC00
NOMESCO Finland
Treatment plan or consultation
4.6
30.5
106
342
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
121.6
30.4
32
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
29.8
28
*
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
+∞
28.7
27
*
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
37.9
28.7
36
11
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
5.3
27.2
67
162
K83.1
ICD-10 Finland
Obstruction of bile duct
31.4
25.2
33
12
JJB30
NOMESCO Finland
Excision of two segments of liver
+∞
24.4
23
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
23.3
22
*
JN4CD
NOMESCO Finland
Very extensive body CT
23.5
23.3
33
16
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
4.5
22.2
66
184
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
+∞
22.2
21
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
22.2
21
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.0
20.6
50
118
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
6.8
19.1
32
53
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
+∞
19.0
18
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
18.0
18.8
29
18
WZC30
NOMESCO Finland
Teaching
4.3
18.7
56
156
JAH01
NOMESCO Finland
Laparoscopy
8.6
18.6
25
32
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
24.0
18.6
26
12
ZXE30
NOMESCO Finland
More than five and less than seven hours
8.2
18.6
26
35
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.5
18.4
52
138
JN3AD
NOMESCO Finland
Abdominal CT examination
4.6
18.4
50
129
WX402
NOMESCO Finland
General anaesthesia
3.9
17.9
64
202
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
17.9
17
*
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
7.1
17.0
27
42
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
96.6
16.8
18
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
181.5
16.7
17
*
B01AB04
ATC
dalteparin; parenteral
6.4
16.6
29
50
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
32.5
16.4
21
7
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
+∞
15.8
15
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.1
14.9
82
337
JJB10
NOMESCO Finland
Atypcal resection of liver
+∞
14.7
14
*
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
+∞
14.7
14
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
14.7
14
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
14.7
14
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.1
14.2
78
319
TPH07
NOMESCO Finland
Cathetrisation of artery
3.9
14.0
47
141
XX3DW
NOMESCO Finland
Time consuming IT work
5.4
14.0
29
59
A06AH03
ATC
naloxegol; oral
79.6
13.7
15
*
L03AA13
ATC
pegfilgrastim; parenteral
147.6
13.6
14
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
16.2
13.4
21
14
B01AB05
ATC
enoxaparin; parenteral
2.7
13.1
104
516
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
6.4
12.8
22
37
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
73.7
12.7
14
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
21.4
12.6
18
9
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.2
12.4
57
209
B01AB10
ATC
tinzaparin; parenteral
4.2
12.3
36
97
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
49.2
12.0
14
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.5
11.9
46
151
C24.09
ICD-10 Finland
Biliary duct or passage NOS
+∞
11.5
11
*
D77
ICPC
Malignant digestive neopl other/NOS
+∞
11.5
11
*
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
125.5
11.5
12
*
A05AA02
ATC
ursodeoxycholic acid; oral
16.0
11.5
18
12
ZX120
NOMESCO Finland
Intravenous
4.3
11.4
31
79
JAH00
NOMESCO Finland
Laparotomy
10.3
11.0
21
22
K81.0
ICD-10 Finland
Acute cholecystitis
9.9
10.7
21
23
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.8
10.6
67
291
115
Kela drug reimbursment
Breast cancer
+∞
10.5
10
*
K82.9
ICD-10 Finland
Disease of gallbladder, unspecified
+∞
10.5
10
*
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
+∞
10.5
10
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
10.5
10
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
10.5
10
*
R50.9
ICD-10 Finland
Fever, unspecified
3.1
10.4
49
181
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
10.4
50
187
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
9.8
10.2
20
22
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
41.9
10.1
12
*
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
41.9
10.1
12
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
9.4
9
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
9.4
9
*
L02BG04
ATC
letrozole; oral
+∞
9.4
9
*
JLC30
NOMESCO Finland
Pancreatoduodenectomy
+∞
9.4
9
*
A04AD12
ATC
aprepitant; systemic
+∞
9.4
9
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
9.1
9.0
18
21
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
7.7
8.9
20
28
UJK12
NOMESCO Finland
Peroral cholangioscopy
51.8
8.7
10
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
93.0
8.5
9
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
8.4
8
*
1560A
ICD-9 Finland
Malignant neoplasm of gallbladder and extrahepatic bile ducts, Gallbladder
+∞
8.4
8
*
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
+∞
8.4
8
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
8.4
8
*
8160/3-C22.1
ICD-O-3
Cholangiocarcinoma of intrahepatic bile duct
+∞
8.4
8
*
XJA00
NOMESCO Finland
Intraoperative abdominal ultrasonography
+∞
8.4
8
*
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
+∞
8.4
8
*
A79
ICPC
Malignancy NOS
+∞
8.4
8
*
J01MA12
ATC
levofloxacin; systemic
2.4
7.7
61
292
A07EC02
ATC
mesalazine; oral, rectal
4.1
7.7
22
58
XQ902
NOMESCO Finland
Other photography
25.9
7.6
10
*
PJA12
NOMESCO Finland
Sentinel node biopsy
82.4
7.5
8
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
7.2
7.4
17
25
K82.8
ICD-10 Finland
Other specified diseases of gallbladder
+∞
7.3
7
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
7.3
7
*
C24.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of biliary tract
+∞
7.3
7
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
7.3
7
*
8010/3-C23.9
ICD-O-3
Carcinoma, NOS, of gallbladder
+∞
7.3
7
*
8160/3-C24.9
ICD-O-3
Cholangiocarcinoma of billiary tract, NOS
+∞
7.3
7
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
7.3
7
*
C24.0
ICD-10 Finland
Malignant neoplasm: Extrahepatic bile duct
+∞
7.3
7
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
7.3
7
*
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
+∞
7.3
7
*
PJD99
NOMESCO Finland
Excision of other lymph nodes
+∞
7.3
7
*
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
31.0
7.2
9
*
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
31.0
7.2
9
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.3
6.9
18
44
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.6
6.9
14
17
WF002
NOMESCO Finland
Radical radiotherapy
23.2
6.7
9
*
R18
ICD-10 Finland
Ascites
10.4
6.6
12
12
L03AA02
ATC
filgrastim; parenteral
71.6
6.5
7
*
WW500
NOMESCO Finland
Blood transfusion
6.9
6.4
15
23
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
11.4
6.4
11
10
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
18.6
6.3
9
5
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
6.3
6
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
6.3
6
*
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
+∞
6.3
6
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
6.3
6
*
WX004
NOMESCO Finland
Patient-controlled sedation
+∞
6.3
6
*
JK4ZT
NOMESCO Finland
Percutaneous transhepatic implantation of bile duct prothesis
+∞
6.3
6
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
6.3
6
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
6.3
6
*
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
ZXD05
NOMESCO Finland
Urgent procedure
2.1
6.2
78
449

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
136
109
25.93
152.34
6.6
1.3
14.69
2.64
ug/l
1.82
128
88
82
46
25.94
106.48
6.7
1.7
1407.41
14.39
u/ml
1.52
76
37
62
18
45.36
100.88
3.2
1.4
590.91
208.04
u/ml
0.27
62
18
49
48
12.43
45.45
1.6
1.3
—
—
—
0
0
89
184
6.93
44.54
7.2
1.9
25.12
6.27
umol/l
2.39
83
155
68
119
7.46
39.65
1.6
1.1
—
—
—
0
0
73
142
6.83
38.37
3.5
1.8
0.19
0.20
g/l
0.57
73
126
170
935
3.51
19.92
22.8
3.4
19.61
11.62
umol/l
1.72
170
866
111
496
3.21
18.01
5.9
3.9
—
—
—
0
0
54
151
4.28
17.87
6.3
5.5
6.02
10.63
mmol/l
6.37
54
141
162
959
2.93
14.98
14.2
15.6
1.21
1.36
inr
2.13
56
276
93
418
2.94
14.36
9.1
3.2
87.35
86.99
%
0.05
93
407
139
776
2.76
14.11
3.3
2.1
—
—
—
0
0
106
517
2.81
13.98
3.0
2.0
—
—
—
0
0
33
86
4.26
11.80
6.7
8.0
—
—
—
0
0
17
9
20.14
11.76
1.5
1.0
—
—
—
0
0
59
250
2.78
9.76
2.2
1.7
—
—
—
0
0
39
132
3.31
9.54
1.5
1.2
—
—
—
0
0
101
558
2.35
9.53
3.1
1.6
—
—
—
0
0
37
125
3.30
9.06
1.4
1.2
—
—
—
0
0
77
398
2.35
8.29
1.3
1.2
—
—
—
0
0
147
1003
2.12
7.73
20.2
5.5
4.08
4.27
e9/l
0.42
138
860
154
1923
0.49
6.77
5.0
5.4
2.70
2.67
mmol/l
0.16
136
1737
149
1870
0.50
6.37
4.8
4.8
4.72
4.58
mmol/l
0.68
134
1696
50
240
2.35
6.23
2.2
2.3
23.22
22.39
%
0.14
43
209
153
1899
0.51
6.19
4.6
4.9
6.23
6.06
mmol/l
0.56
142
1698
153
1112
1.96
6.18
7.5
2.9
136.22
46.49
u/l
5.85
148
1014
148
1852
0.51
6.04
4.5
4.8
1.48
1.50
mmol/l
0.19
133
1673
137
965
1.92
6.03
7.1
5.0
1.19
1.22
mmol/l
4.53
120
837
153
1118
1.94
6.02
7.4
4.2
6.84
6.82
mmol/l
0.06
148
1033
45
222
2.25
5.23
6.1
6.1
0.92
1.45
mmol/l
0.55
36
179
144
1791
0.54
5.21
4.3
4.3
1.32
1.25
mmol/l
0.59
129
1601
146
1808
0.54
5.19
6.1
6.4
41.52
40.70
mmol/mol
0.38
131
1660
123
871
1.81
5.02
5.7
4.6
1.19
1.22
mmol/l
3.45
118
779
8
7
11.75
4.81
3.8
1.4
2.29
5.81
nmol/l
—
8
7
52
287
2.02
4.52
2.4
2.1
12.64
12.57
umol/l
0.02
52
258
90
596
1.79
4.49
3.4
2.9
7.41
7.40
ph
0.69
22
87
20
72
2.93
4.40
1.9
1.6
0.73
1.88
ug/l
1.09
20
62
7
7
10.24
4.03
1.0
1.0
—
—
—
0
0
67
420
1.81
3.94
12.2
4.5
—
—
—
0
0
23
96
2.54
3.85
6.7
6.1
24.87
25.51
mmol/l
0.51
23
96
181
2064
0.56
3.85
47.3
19.4
37.09
39.83
%
7.40
168
1895
181
2064
0.56
3.85
47.1
19.6
123.28
134.01
g/l
16.12
181
2020
181
2064
0.56
3.85
46.7
19.3
30.22
30.33
pg
0.31
181
2022
181
2062
0.57
3.78
46.9
19.4
91.54
91.45
fl
0.08
181
2020
149
1772
0.61
3.50
4.6
4.9
2.00
1.95
mu/l
0.16
138
1589
84
579
1.68
3.49
2.3
2.9
51.51
154.78
e6/l
0.42
69
431
29
141
2.19
3.48
4.7
2.6
1.22
1.23
mmol/l
0.03
29
114
34
594
0.51
3.44
2.9
3.3
—
—
—
0
0
41
229
1.94
3.42
7.5
5.3
104.61
104.20
mmol/l
0.29
41
229
6
7
8.74
3.28
1.3
1.4
21.63
13.25
ug/l
—
6
7
77
528
1.66
3.23
2.3
2.9
0.51
0.48
e6/l
0.06
61
384
11
30
3.79
3.12
1.5
2.5
61.18
60.77
%
0.04
11
30
23
107
2.26
3.07
2.7
3.4
1.12
0.21
%
1.07
17
28
25
121
2.18
3.05
2.8
3.3
1.28
0.83
%
0.35
18
35
74
510
1.64
3.02
2.3
2.8
—
—
—
0
0
23
113
2.14
2.71
7.1
7.4
1.36
1.46
%
0.21
23
113
23
113
2.14
2.71
7.5
7.3
0.70
0.71
%
0.08
23
113
10
30
3.43
2.63
1.5
1.9
3.64
4.68
e9/l
—
10
30
27
143
1.99
2.63
4.7
3.7
—
—
—
0
0
179
1996
0.64
2.47
40.3
15.7
72.75
78.33
umol/l
2.67
179
1996
5
8
6.35
2.38
1.2
1.3
—
—
—
0
0
132
1558
0.68
2.38
40.3
17.8
330.86
331.08
g/l
0.11
132
1547
5
153
0.31
2.38
1.8
2.5
—
17.88
—
0
8
89
672
1.50
2.37
2.5
3.5
106.99
116.94
e6/l
0.09
70
467
105
820
1.48
2.37
5.2
5.1
—
—
—
0
0
174
1942
0.66
2.26
31.9
12.9
—
—
—
0
0
7
176
0.38
2.13
1.9
1.5
—
—
—
0
0
24
134
1.87
2.04
4.7
4.6
—
—
—
0
0
9
32
2.88
2.02
2.7
2.5
—
—
—
0
0
35
528
0.61
2.00
1.8
1.7
1.30
1.30
mmol/l
0.00
28
438
181
1990
0.68
1.96
28.2
9.1
33.64
24.16
u/l
6.49
181
1899
5
11
4.61
1.95
1.0
1.1
—
—
—
0
0
21
115
1.90
1.89
3.0
3.4
0.06
0.07
%
0.03
16
29
26
153
1.78
1.88
7.5
6.0
—
—
—
0
0
100
802
1.41
1.87
5.0
4.8
0.59
0.68
%
1.06
95
721
5
12
4.23
1.83
1.4
1.8
—
—
—
0
0
103
833
1.40
1.82
5.0
4.7
2.43
2.97
%
1.37
98
755
19
328
0.54
1.79
1.1
1.3
41.81
42.72
iu/ml
0.01
11
112
103
838
1.39
1.74
5.5
4.9
9.40
8.66
%
0.98
98
761
5
130
0.37
1.68
1.0
1.3
—
48.28
—
0
10
7
25
2.85
1.66
1.1
1.2
95.57
74.26
pmol/l
—
7
25
103
848
1.36
1.59
5.2
4.9
24.52
27.20
%
1.49
98
769
51
679
0.69
1.59
4.3
3.7
12.13
6.64
mg/mmol
0.32
27
405
24
147
1.70
1.54
1.2
1.4
—
—
—
0
0
128
1460
0.75
1.47
3.7
4.0
15.27
15.01
pmol/l
0.48
115
1307
7
28
2.54
1.46
1.7
3.5
—
—
—
0
0
49
648
0.70
1.46
3.8
3.0
6.19
7.07
mmol/l
1.00
41
536
0
40
0.00
1.34
0.0
2.4
—
—
—
0
0
6
24
2.54
1.31
1.3
1.1
—
—
—
0
0
6
24
2.54
1.31
1.2
1.0
—
—
—
0
0
106
900
1.31
1.27
5.5
4.6
0.62
0.60
e9/l
0.33
94
765
8
37
2.20
1.22
2.5
2.6
2.05
3.27
mmol/l
—
8
23
8
37
2.20
1.22
2.5
2.6
4.88
5.14
kpa
—
8
37
8
37
2.20
1.22
2.5
2.6
8.29
7.92
kpa
—
8
37
106
905
1.30
1.21
5.5
4.6
0.04
0.04
e9/l
0.64
93
768
20
305
0.63
1.20
1.1
1.3
1.19
14.45
u/ml
—
8
109
18
110
1.69
1.19
3.1
3.4
0.17
0.04
%
0.31
12
23
65
520
1.34
1.17
4.4
4.0
0.00
0.00
estimate
-0.00
30
154
5
20
2.53
1.15
1.2
1.5
90.42
89.24
%
—
5
20
82
681
1.30
1.14
2.9
3.4
—
—
—
0
0
40
297
1.41
1.14
1.5
1.7
31.22
29.19
s
1.37
40
284
51
644
0.74
1.13
3.6
3.1
1585.06
254.21
mg/l
0.41
28
398
106
914
1.28
1.10
5.7
4.7
1.58
1.82
e9/l
2.52
96
794
7
33
2.15
1.06
2.0
2.1
—
—
—
0
0
108
938
1.26
1.04
5.6
4.7
0.16
0.20
e9/l
1.62
97
802
17
107
1.63
1.02
2.9
3.7
4.92
5.22
kpa
0.73
17
102
5
23
2.20
0.98
1.4
1.1
—
—
—
0
0
5
23
2.20
0.98
1.2
1.0
—
—
—
0
0
129
1429
0.80
0.97
4.3
4.2
19.65
13.01
mm/h
3.22
122
1292
13
77
1.73
0.97
1.1
1.2
—
—
—
0
0
6
28
2.17
0.92
1.8
1.1
—
—
—
0
0
16
103
1.59
0.90
1.3
1.3
—
—
—
0
0
8
47
1.72
0.81
1.3
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
6
33
1.84
0.79
1.0
1.1
—
—
—
0
0
38
299
1.32
0.78
2.1
2.8
5.56
3.37
e6/l
0.30
16
152
6
34
1.78
0.77
1.3
1.2
—
—
—
0
0
8
135
0.58
0.75
1.3
1.4
—
—
—
0
0
5
25
2.02
0.73
1.4
1.4
—
—
nmol/l
—
0
0
61
516
1.24
0.72
3.5
3.7
—
—
—
0
0
19
137
1.42
0.67
1.7
1.2
—
—
—
0
0
21
155
1.39
0.65
2.1
1.3
66.73
66.95
g/l
0.04
21
134
23
177
1.33
0.57
4.3
3.1
—
—
—
0
0
45
529
0.82
0.56
4.5
3.9
2.40
2.09
ug/l
0.32
36
461
12
82
1.49
0.55
3.3
4.3
—
—
—
0
0
141
1315
1.16
0.55
4.9
4.5
—
—
—
0
0
80
891
0.85
0.55
2.0
2.0
95.56
92.72
pmol/l
0.24
47
413
94
853
1.16
0.52
4.0
3.9
43.55
75.86
ng/l
0.33
77
628
6
40
1.51
0.52
3.0
2.0
1.33
1.59
mg/l
—
6
34
16
118
1.38
0.51
2.9
2.4
—
—
—
0
0
67
594
1.17
0.49
3.6
4.2
—
—
—
0
0
0
15
0.00
0.41
0.0
2.7
—
—
—
0
0
5
34
1.48
0.40
2.6
1.7
73.80
62.75
%
—
5
34
7
105
0.66
0.40
1.0
1.2
—
106.99
iu/ml
—
0
39
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
34.05
—
0
19
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
26
218
1.21
0.36
1.4
1.4
—
—
—
0
0
6
44
1.37
0.34
2.3
1.8
111.17
131.88
g/l
—
6
26
6
45
1.34
0.34
1.3
1.1
—
—
—
0
0
103
965
1.11
0.33
3.9
3.9
0.00
0.00
estimate
-0.00
32
157
22
183
1.22
0.33
2.1
1.2
—
—
—
0
0
54
487
1.14
0.33
1.8
1.7
492.78
453.89
pmol/l
0.46
46
392
86
800
1.11
0.32
21.2
8.0
0.00
0.00
e9/l
0.66
75
650
101
949
1.11
0.31
3.8
3.9
0.00
0.00
estimate
-0.00
33
174
20
166
1.22
0.31
3.4
2.9
—
—
—
0
0
7
54
1.30
0.30
1.9
1.8
—
—
—
0
0
10
130
0.76
0.30
1.1
1.3
—
—
—
0
0
25
291
0.84
0.30
2.2
2.6
0.94
0.75
ug/l
0.56
16
192
35
395
0.87
0.29
1.2
1.2
0.66
1.74
u/ml
—
8
107
8
63
1.28
0.28
4.3
4.5
25.42
25.27
mmol/l
—
8
58
101
956
1.09
0.26
4.7
5.3
0.00
0.00
estimate
-0.00
31
156
5
75
0.66
0.26
1.4
1.2
—
—
—
0
0
12
146
0.81
0.23
1.6
1.5
—
—
—
0
0
31
278
1.13
0.21
1.4
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.8
—
26.67
—
0
6
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
8.11
—
0
10
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
9.00
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
9
111
0.80
0.20
3.3
2.2
0.56
0.67
%
—
9
111
9
113
0.79
0.20
3.3
2.2
1.19
1.23
%
—
9
113
6
51
1.18
0.19
3.8
2.6
—
—
—
0
0
48
446
1.09
0.18
1.7
1.7
1196.46
1209.37
nmol/l
0.03
39
339
46
433
1.08
0.14
4.1
4.2
204.79
226.92
ng/l
0.06
34
373
15
132
1.14
0.13
1.1
1.2
—
—
—
0
0
44
464
0.94
0.11
4.3
4.1
1.02
1.02
kg/l
0.34
13
75
10
115
0.86
0.11
2.6
4.1
—
—
—
0
0
5
45
1.11
0.10
2.8
2.6
—
—
—
0
0
8
75
1.07
0.07
1.8
1.9
—
—
—
0
0
8
75
1.07
0.07
1.4
1.2
—
—
—
0
0
8
90
0.89
0.07
1.8
2.3
13.18
16.01
nmol/l
—
8
83
135
1370
0.97
0.06
4.4
4.0
—
—
—
0
0
16
171
0.93
0.05
3.6
2.6
4.46
4.35
kpa
0.09
16
164
41
420
0.97
0.03
1.4
1.7
2.02
1.19
mg/l
0.64
32
321
45
454
0.99
0.00
3.7
3.6
—
—
—
0
0
14
144
0.97
0.00
3.3
2.7
—
—
—
0
0
33
326
1.01
0.00
1.5
1.2
2.04
2.56
g/l
1.78
24
176
24
245
0.98
0.00
1.6
1.3
128.00
523.43
titre
—
5
70
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
67
0.89
-0.00
3.3
4.4
3.48
3.95
mmol/l
—
6
67
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
54
0.92
-0.00
3.0
3.3
6.98
7.93
mmol/l
—
5
54
6
66
0.91
-0.00
1.2
1.1
34.75
37.93
g/l
—
6
56
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
51.20
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
-0.00
4.7
4.0
—
—
—
0
0
23
230
1.00
-0.00
2.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.86
—
0
5
7
71
0.99
-0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
12.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
5.2
3.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.87
-0.00
3.0
3.2
1.26
1.56
mmol/l
—
5
57

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_GALLBLADDER_WIDE – Malignant neoplasm of gallbladder, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).