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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_GALLBLADDER_EXALLC for full statistics.

Malignant neoplasm of gallbladder

C3_GALLBLADDER

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C23&
  • Cause of death: ICD-9 1560
  • Cause of death: ICD-8 1560
  • Cancer registry: Topography ICD-O-3 C23
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

156

4. Check minimum number of events

None

156

5. Include endpoints

None

156

6. Filter based on genotype QC (FinnGen only)

156

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF9

Similar endpoints

List of similar endpoints to Malignant neoplasm of gallbladder based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

None

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 156 97 59
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 72.06 72.46 71.40

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
138
Matched controls
1378
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
8818.7
160.3
122
*
8140/3-C23.9
ICD-O-3
Adenocarcinoma, NOS, of gallbladder
+∞
107.9
89
*
130
Kela drug reimbursment
Malignant tumour
17.6
39.5
68
72
8000/3-C23.9
ICD-O-3
Neoplasm, malignant of gallbladder
+∞
24.7
23
*
A03FA01
ATC
metoclopramide; systemic, rectal
7.0
23.2
72
185
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
17.6
22.0
35
26
UJK02
NOMESCO Finland
ERCP
26.6
20.5
28
13
L01BC06
ATC
capecitabine; oral
16.3
20.2
33
26
A04AA02
ATC
granisetron; systemic, transdermal
11.8
19.8
38
43
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
26.3
19.0
26
12
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
39.0
18.6
23
7
K83.0
ICD-10 Finland
Cholangitis
61.4
18.5
21
*
H02AB02
ATC
dexamethasone; systemic
8.3
18.1
43
71
JKA20
NOMESCO Finland
Cholecystectomy
13.4
17.6
31
29
Z51.5
ICD-10 Finland
Palliative care
10.5
17.4
35
43
N02AA05
ATC
oxycodone; systemic
5.8
17.3
58
153
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
8.0
16.9
41
69
WX302
NOMESCO Finland
Thoracal epidural anesthesy
10.9
16.4
32
37
JJB30
NOMESCO Finland
Excision of two segments of liver
179.5
15.8
16
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
18.1
15.0
23
15
K83.1
ICD-10 Finland
Obstruction of bile duct
48.1
14.5
17
*
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
34.1
14.3
18
6
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
7.5
13.2
32
53
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
6.3
13.0
37
76
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
27.4
12.8
17
7
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
41.7
12.5
15
*
JN4CD
NOMESCO Finland
Very extensive body CT
10.4
11.8
23
26
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
130.4
11.6
12
*
JJB10
NOMESCO Finland
Atypcal resection of liver
+∞
10.5
10
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
9.0
10.1
21
27
C24.9
ICD-10 Finland
Malignant neoplasm: Biliary tract, unspecified
39.5
9.2
11
*
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
7.3
8.9
21
33
JN4BD
NOMESCO Finland
Extensive body CT
4.6
8.9
32
85
JK3NB
NOMESCO Finland
Percutaneous transhepatic cholangiography
53.5
8.8
10
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.8
8.5
24
48
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
11.9
8.5
15
14
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
11.1
8.3
15
15
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
26.7
7.7
10
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.1
7.6
24
55
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.0
7.6
55
252
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
84.4
7.5
8
*
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
+∞
7.4
7
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.0
7.3
30
90
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
11.8
6.9
12
11
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
6.7
50
229
K82.9
ICD-10 Finland
Disease of gallbladder, unspecified
73.1
6.5
7
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.9
6.4
20
46
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
28.1
6.3
8
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
8.3
6.3
13
17

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_GALLBLADDER – Malignant neoplasm of gallbladder

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).