appendicitis: Acute inflammation of the vermiform appendix.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3563 |
4. Check minimum number of eventsNone |
3563 |
5. Include endpointsNone |
3563 |
6. Filter based on genotype QC (FinnGen only) |
3563 |
Control definitions (FinnGen only)
- Control exclude
- K11_APPENDIX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other appendicitis
based on the number of shared cases.
Similar with more cases:
- Appendicitis, broad definition
- Diseases of appendix
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 30807 | 15923 | 14710 |
| Only index persons | 27597 | 14579 | 13018 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.43 | 0.46 | 0.41 |
| Only index persons | 0.52 | 0.54 | 0.50 |
| Median age at first event (years) | |||
| Whole population | 26.65 | 26.67 | 26.39 |
| Only index persons | 25.39 | 25.68 | 25.07 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3563 | 2101 | 1462 |
| Unadjusted period prevalence (%) | 0.69 | 0.72 | 0.64 |
| Median age at first event (years) | 28.11 | 26.74 | 30.08 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3225
- Matched controls
- 32249
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
54199
ICD-8 Finland
Appendicitis, unqualified
+∞
323.0
1187
*
JEA01
NOMESCO Finland
Laparoscopic appendectomy
75.9
323.0
512
80
5410X
ICD-9 Finland
Appendicitis, unqualified[APPENDICITIS NUD]
+∞
323.0
600
*
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
536.4
323.0
463
10
K37
ICD-10 Finland
Unspecified appendicitis
642.8
323.0
668
13
6421
FHL
Appendicectomy
30.1
323.0
715
302
K36
ICD-10 Finland
Other appendicitis
+∞
279.3
264
*
54200
ICD-8 Finland
Other appendicitis, Appendicitis chronica
+∞
220.4
209
*
5428X
ICD-9 Finland
Other appendicitis[APPENDICITIS ALIA DEFINITA]
+∞
103.7
99
*
54208
ICD-8 Finland
Other appendicitis
+∞
100.5
96
*
JEA00
NOMESCO Finland
Appendectomy
7.1
82.8
212
316
K35.1
ICD-10 Finland
Acute appendicitis with peritoneal abscess
+∞
81.6
78
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
65.2
1190
7338
K35.0
ICD-10 Finland
Acute appendicitis with generalized peritonitis
+∞
63.7
61
*
54003
ICD-8 Finland
Acute appendicitis, Cum abscessu
+∞
44.9
43
*
5420A
ICD-9 Finland
Other appendicitis[APPENDICITIS CHRONICA]
+∞
43.8
42
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.5
43.3
379
1643
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
41.0
704
4100
P01AB01
ATC
metronidazole; oral, rectal
1.7
38.8
1232
8699
54099
ICD-8 Finland
Acute appendicitis, Without mention of peritonitis
+∞
38.6
37
*
5409X
ICD-9 Finland
Acute appendicitis, Without mention of peritonitis
+∞
34.4
33
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.4
28.2
253
1102
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
27.8
775
5173
N02BE01
ATC
paracetamol; systemic, rectal
1.6
25.1
2604
23339
5401A
ICD-9 Finland
Acute appendicitis, With peritoneal abscess
+∞
25.0
24
*
A02BC05
ATC
esomeprazole; systemic
1.5
24.3
1175
8911
N02AX02
ATC
tramadol; systemic, rectal
1.5
24.1
1206
9208
J01DB01
ATC
cefalexin; oral
1.5
21.0
2471
22127
A02BC02
ATC
pantoprazole; systemic
1.4
19.9
1855
15773
54201
ICD-8 Finland
Other appendicitis, Appendicitis recidivans
+∞
19.8
19
*
M01AB05
ATC
diclofenac; systemic, rectal
1.4
18.3
2001
17371
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
17.6
1333
10824
D88
ICPC
Appendicitis
170.8
16.5
17
*
J01AA02
ATC
doxycycline; systemic
1.4
16.4
2323
20874
WX402
NOMESCO Finland
General anaesthesia
1.6
16.0
478
3196
M03BX02
ATC
tizanidine; oral
1.4
15.6
1851
16069
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
15.2
440
2916
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
2.7
14.8
101
382
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
14.6
672
4937
N03AX16
ATC
pregabalin; oral
1.5
14.4
632
4600
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
14.2
1040
8305
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
13.8
403
2678
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.1
13.3
160
800
UJF32
NOMESCO Finland
Coloscopy
1.4
13.0
643
4782
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
12.9
2761
25916
M01AE02
ATC
naproxen; oral, rectal
1.3
12.9
1608
13881
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
12.4
335
2179
H02AB06
ATC
prednisolone; systemic
1.3
11.7
1243
10429
K35
ICD-10 Finland
Acute appendicitis
16.4
11.7
18
11
M79.6
ICD-10 Finland
Pain in limb
1.3
11.6
936
7543
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
11.6
1189
9928
5421A
ICD-9 Finland
Other appendicitis[APPENDICITIS RECIDIVANS]
+∞
11.5
11
*
A02BC03
ATC
lansoprazole; oral
1.4
10.9
757
5947
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
10.6
1063
8819
54191
ICD-8 Finland
NA
+∞
10.4
10
*
R51.80
ICD-10 Finland
Headache
1.5
10.4
373
2593
JAH01
NOMESCO Finland
Laparoscopy
2.0
9.9
119
597
A02BC01
ATC
omeprazole; systemic
1.3
9.5
678
5337
J01MA02
ATC
ciprofloxacin; systemic
1.3
9.4
988
8213
WX704
NOMESCO Finland
Intubation
1.7
9.4
193
1168
D01
ICPC
Abdominal pain/cramps general
1.6
9.1
258
1697
J01MA12
ATC
levofloxacin; systemic
1.4
8.9
437
3224
99850
ICD-8 Finland
Other complications of surgical procedures, Postoperative wound infection
5.2
8.9
26
50
R51
ICD-10 Finland
Headache
1.9
8.8
134
736
R10.0
ICD-10 Finland
Acute abdomen
2.2
8.5
80
364
A03FA02
ATC
cisapride; oral, rectal
1.7
8.4
184
1133
54100
ICD-8 Finland
NA
+∞
8.3
8
*
AA1AD
NOMESCO Finland
CT of head and brain
1.3
8.0
527
4084
R03AC02
ATC
salbutamol; inhalant
1.2
8.0
1425
12569
N03AX12
ATC
gabapentin; oral
1.4
8.0
375
2745
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
8.0
473
3607
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
7.9
406
3019
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
2.1
7.9
90
443
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
7.9
985
8332
M01AH05
ATC
etoricoxib; oral
1.2
7.8
1667
14979
WX110
NOMESCO Finland
Local anesthesy
1.2
7.8
1951
17839
J01DA06
ATC
[U] cefuroxime; systemic
1.4
7.7
372
2740
J01FA10
ATC
azithromycin; systemic
1.2
7.6
1637
14708
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
7.4
1041
8915
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
7.4
681
5537
Y0599
ICD-8 Finland
Investigation of digestive system
2.7
7.3
47
174
J01EA01
ATC
trimethoprim; systemic
1.3
7.3
606
4859
54091
ICD-8 Finland
Acute appendicitis, Gangraenosa, peritonitide non indicata
+∞
7.3
7
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
7.2
563
4475
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
7.1
499
3900
G44.2
ICD-10 Finland
Tension-type headache
1.4
7.1
326
2375
J01FA09
ATC
clarithromycin; systemic
1.3
7.0
847
7116
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
7.0
439
3378
A02BA04
ATC
nizatidine; systemic
1.6
7.0
174
1113
M01AH01
ATC
celecoxib; oral (coxibs)
1.3
7.0
435
3343
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.9
1960
18034
SPAT1263
SPAT
Sampling
1.2
6.9
1086
9405
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
6.8
137
825
N05BA04
ATC
oxazepam; oral
1.3
6.8
613
4960
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.4
6.8
269
1905
R50.9
ICD-10 Finland
Fever, unspecified
1.4
6.8
315
2302
J01FA06
ATC
roxithromycin; oral
1.2
6.7
1070
9270
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.4
6.7
349
2603
R06.0
ICD-10 Finland
Dyspnoea
1.3
6.7
559
4484
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.7
1375
12232
N05BA01
ATC
diazepam; systemic, rectal
1.4
6.6
317
2329
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
6.6
1530
13770
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
6.5
288
2086
1220
FHL
Arthroscopy
1.8
6.5
100
557
R03BA05
ATC
fluticasone; inhalant
1.3
6.5
441
3434
ZXA10
NOMESCO Finland
Bilateral
1.3
6.5
401
3079
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
6.4
410
3159
D37.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Appendix
7.4
6.4
14
19
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
6.3
510
4066
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
6.3
209
1427
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.0
6.3
76
388
C07AB07
ATC
bisoprolol; oral
1.2
6.3
1087
9487
K38.9
ICD-10 Finland
Disease of appendix, unspecified
+∞
6.2
6
*
54190
ICD-8 Finland
NA
+∞
6.2
6
*
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.2
672
5566
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
1.9
6.1
81
426
G43.9
ICD-10 Finland
Migraine, unspecified
1.6
6.1
132
814
UKC02
NOMESCO Finland
Cystoscopy
1.4
6.1
333
2499
A02BA02
ATC
ranitidine; systemic
1.3
6.1
456
3595
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.6
6.1
135
839
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.4
6.1
250
1784
M01AX17
ATC
nimesulide; oral
1.3
6.0
582
4750
N05CF01
ATC
zopiclone; oral
1.2
6.0
768
6477
NA1CM
NOMESCO Finland
Cervical spine extensive MRI examination with 3 Tesla magnet
10.0
6.0
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1244
8743
1.65
40.99
2.6
2.6
52.4
58.4
u/l
7.91
1169
8104
1344
10167
1.52
29.68
3.7
3.4
32.1
49.3
ng/l
1.68
859
6493
1806
14527
1.49
29.52
5.3
6.3
10.8
11.2
umol/l
0.86
1736
13810
2148
18371
1.43
22.49
4.4
4.1
61.1
1947.5
e6/l
3.77
25
253
2482
21987
1.42
19.96
7.4
7.6
76.0
77.2
u/l
0.96
2353
20799
1916
16300
1.38
19.21
4.9
4.7
6.8
6.7
mmol/l
1.28
1821
15211
982
7486
1.43
18.79
3.1
3.0
0.4
0.4
e6/l
0.25
749
5616
765
5630
1.46
17.51
2.5
2.5
6.7
5.9
e6/l
0.74
666
4937
1598
13330
1.36
17.47
4.1
3.9
—
—
—
0
0
1335
10843
1.37
17.23
3.7
3.6
—
—
—
0
0
1675
14125
1.35
16.83
3.6
3.5
0.0
0.0
estimate
1.72
394
2470
1042
8182
1.39
16.37
3.2
3.1
77.6
86.2
e6/l
0.13
806
6249
1654
13985
1.34
16.04
4.9
4.7
0.0
0.0
estimate
0.50
404
2578
1651
13963
1.34
15.95
3.6
3.5
0.0
0.0
estimate
0.50
393
2505
3170
30005
1.51
13.15
16.4
14.5
139.6
139.7
mmol/l
3.69
3116
29282
3111
29389
1.46
12.48
15.3
13.1
25.1
22.4
mg/l
3.89
2661
22960
3174
30117
1.49
12.30
16.5
14.6
4.0
4.0
mmol/l
0.03
3117
29333
1893
16692
1.29
12.04
8.4
9.2
4.5
4.0
e9/l
13.85
1683
14636
925
7418
1.33
11.99
3.8
3.8
0.0
0.0
estimate
0.21
385
2502
2962
27831
1.38
11.41
13.1
12.0
84.0
83.9
ml/min/173m2
0.07
2497
23004
178
1054
1.73
10.37
2.5
2.3
7343.4
4803.8
u/l
0.43
56
426
2236
20325
1.27
10.27
3.2
3.1
48.7
46.4
u/l
0.49
2128
19122
2346
21450
1.27
10.26
4.3
4.0
11.8
11.4
mm/h
0.72
2182
20002
1002
8278
1.29
10.17
2.1
2.1
239.4
229.0
u/l
0.08
934
7822
278
1882
1.52
9.38
1.6
1.7
—
—
—
0
0
121
697
1.76
7.85
1.7
1.7
—
—
—
0
0
542
4259
1.32
7.74
2.7
2.8
2.7
2.7
e6/l
0.01
266
2280
814
6756
1.27
7.61
2.3
2.2
—
—
—
0
0
2823
26744
1.27
7.41
5.7
5.3
39.5
39.3
mmol/mol
0.55
2619
25026
305
2205
1.42
7.36
4.0
4.0
1.2
1.2
mmol/l
0.14
271
1928
2638
24840
1.24
7.07
17.7
15.9
13.6
13.6
%
0.83
2592
24291
2159
19964
1.21
6.75
3.2
3.1
—
—
—
0
0
1439
12827
1.20
6.63
10.7
9.2
0.0
0.0
e9/l
0.04
1218
10491
1513
13556
1.20
6.58
7.2
6.6
1.2
1.2
mmol/l
0.85
1225
11495
769
6446
1.25
6.48
1.6
1.8
1.2
1.1
mg/l
0.37
591
4893
2421
22688
1.21
6.35
4.3
4.0
14.6
14.7
pmol/l
0.32
2212
20858
1377
12267
1.20
6.29
6.3
5.9
1.2
1.2
mmol/l
0.60
1250
11185
1555
14021
1.19
6.18
6.4
6.2
28.4
28.4
%
0.02
1463
13109
1536
13842
1.19
6.12
6.1
6.0
57.2
57.0
%
0.43
1452
12979
2827
26976
1.23
5.85
5.0
4.6
3.1
2.1
mu/l
0.47
2600
24979
560
4577
1.27
5.83
2.6
2.6
1.2
1.0
e6/l
0.28
284
2582
880
7558
1.22
5.81
2.6
2.5
2122.2
4294.6
umol/l
1.44
768
6671
226
1620
1.42
5.76
3.0
3.5
5.1
5.2
kpa
0.33
212
1505
216
1536
1.43
5.76
2.9
3.5
1.8
1.8
mmol/l
0.06
160
1145
363
2809
1.33
5.75
3.6
3.2
—
—
—
0
0
1498
13521
1.19
5.75
6.3
6.1
2.9
2.9
%
0.54
1411
12623
666
5574
1.24
5.62
1.5
1.5
—
—
—
0
0
631
5264
1.24
5.48
1.3
1.3
24.4
31.4
iu/ml
1.30
205
1678
94
569
1.67
5.22
4.0
3.7
56.6
57.5
%
0.28
94
569
823
7091
1.21
5.19
2.9
2.9
1262.4
1185.6
ng/l
0.14
684
5989
766
6565
1.21
5.09
1.3
1.3
1.3
1.8
u/ml
1.28
203
1804
109
691
1.60
5.06
1.2
1.3
—
—
—
0
0
342
2689
1.30
4.84
2.5
2.5
32.0
56.9
u/l
0.80
296
2340
89
546
1.65
4.73
2.7
2.6
17.1
16.4
%
0.91
42
284
269
2053
1.34
4.71
2.3
2.4
23.4
24.5
au/ml
0.05
19
136
204
1494
1.39
4.65
1.8
1.8
—
—
—
0
0
247
1883
1.33
4.38
3.5
3.1
4.7
4.7
kpa
0.05
242
1818
148
1036
1.45
4.37
2.4
2.0
1.0
2.1
ug/l
1.45
127
933
3235
31536
1.28
4.35
10.6
10.0
27.0
27.0
u/l
0.03
3135
30562
445
3663
1.25
4.34
2.4
2.4
137.3
131.6
ug/g
0.12
343
2941
1297
11813
1.15
4.01
4.9
4.9
35.5
35.9
g/l
1.76
1222
11020
325
2604
1.27
4.00
2.4
2.2
373.0
369.7
nmol/l
0.11
303
2388
285
2247
1.29
3.99
2.5
2.7
10.4
10.6
g/l
0.34
262
2062
244
1886
1.32
3.95
1.2
1.3
51.4
50.3
au/ml
0.02
11
92
243
1883
1.31
3.87
1.8
1.9
—
—
—
0
0
65
394
1.66
3.70
1.3
1.3
6.6
7.1
mmol/l
0.63
44
290
3366
33061
1.33
3.67
21.8
19.1
254.3
254.4
e9/l
0.04
3305
32290
359
2946
1.24
3.62
3.7
4.5
238.4
244.5
u/l
0.29
335
2803
2850
27538
1.17
3.60
15.5
13.9
40.3
40.2
%
0.24
2108
20841
3029
29420
1.20
3.60
4.5
4.2
4.7
4.7
mmol/l
0.04
2830
27636
3012
29241
1.19
3.59
4.4
4.2
1.4
1.5
mmol/l
5.07
2788
27326
143
1041
1.39
3.46
5.2
5.6
1.7
1.7
%
0.20
135
975
3366
33086
1.31
3.43
21.8
19.1
4.5
4.5
e12/l
0.40
3293
32232
134
967
1.40
3.42
1.7
1.7
—
—
—
0
0
490
4175
1.20
3.41
1.9
1.8
—
—
—
0
0
1198
10952
1.14
3.38
1.9
1.9
95.6
96.2
pmol/l
0.16
624
5756
3366
33092
1.31
3.38
21.8
19.2
6.8
6.6
e9/l
4.25
3299
32233
3366
33093
1.31
3.37
21.9
19.2
136.1
136.3
g/l
0.56
3335
32669
2912
28224
1.17
3.36
4.0
3.8
1.4
1.3
mmol/l
4.29
2689
26229
156
1162
1.36
3.30
1.3
1.3
0.2
1.3
u/ml
—
7
106
264
2120
1.26
3.23
1.2
1.2
146.8
153.8
iu/ml
0.09
84
832
1374
12715
1.13
3.16
3.0
2.8
127.9
120.8
ug/l
0.28
1285
11874
136
999
1.38
3.15
3.0
3.6
25.1
24.9
mmol/l
0.30
131
928
153
1148
1.35
3.10
3.1
2.7
0.6
0.7
%
0.37
146
1100
3062
29849
1.18
3.07
4.9
4.6
2.9
2.8
mmol/l
0.57
2841
27852
195
1519
1.30
3.05
1.4
1.5
—
—
—
0
0
390
3305
1.20
2.90
20.8
21.9
1.3
1.3
inr
0.18
44
472
390
3305
1.20
2.90
2.2
2.8
7.5
7.9
umol/l
0.13
345
2884
75
1099
0.68
2.89
1.5
1.5
—
—
—
0
0
2924
28434
1.16
2.86
4.5
4.3
5.9
5.9
mmol/l
0.86
2703
26263
41
238
1.73
2.81
1.2
1.4
14.2
12.3
mmol/l
—
7
60
93
654
1.43
2.80
2.9
3.2
24.2
24.8
mmol/l
0.78
88
576
79
541
1.47
2.74
1.9
1.7
—
—
—
0
0
571
5023
1.16
2.73
1.3
1.3
10.3
11.3
u/ml
0.14
227
2037
481
4178
1.17
2.70
1.8
2.1
29.7
29.8
s
0.12
470
4048
450
3893
1.18
2.66
2.8
2.5
2.4
2.3
g/l
0.66
413
3619
43
258
1.67
2.64
1.8
1.5
32.9
32.7
%
0.01
27
154
279
2317
1.22
2.57
4.7
3.8
1.8
1.9
mmol/l
0.36
226
1859
24
122
1.97
2.50
1.1
1.1
127.7
186.1
iu/ml
1.15
24
122
482
4219
1.16
2.47
2.8
2.5
13.6
13.7
umol/l
0.01
453
3925
274
2282
1.22
2.47
8.0
7.2
1.4
1.4
mmol/l
0.25
269
2197
1066
9834
1.12
2.46
3.3
3.3
30.3
34.3
u/l
1.42
1021
9363
38
228
1.67
2.36
1.9
2.0
20.2
19.0
nmol/l
0.30
38
215
24
125
1.93
2.35
2.7
2.0
27.9
211.2
ug/l
0.48
24
111
46
293
1.58
2.27
2.0
2.4
106.1
105.6
mmol/l
0.35
46
287
46
293
1.58
2.27
2.0
2.4
3.9
4.0
mmol/l
1.49
46
287
13
53
2.46
2.27
1.7
1.2
1.5
43.8
ug/l
—
5
22
25
134
1.87
2.26
1.4
1.3
6.9
4.5
umol/l
0.34
25
128
38
231
1.65
2.26
2.2
2.1
9.8
13.7
%
1.66
20
105
1261
11787
1.11
2.25
2.4
2.2
76.5
76.6
nmol/l
0.04
1141
10779
37
224
1.66
2.24
2.1
2.0
—
—
—
0
0
670
6049
1.13
2.21
3.8
3.8
1.0
1.0
kg/l
0.09
115
869
47
304
1.55
2.19
2.1
2.2
31.3
19.5
mg/l
0.46
12
86
248
2081
1.21
2.11
2.8
2.7
66.3
66.7
g/l
0.34
222
1925
277
2350
1.19
2.09
7.2
8.2
9.2
9.4
mmol/l
0.21
265
2251
110
840
1.32
2.09
1.4
1.3
—
—
—
0
0
81
591
1.38
2.06
2.4
2.2
133.4
130.5
g/l
0.50
59
427
31
184
1.69
2.04
1.5
1.6
7.2
7.9
mmol/l
0.73
12
116
378
3307
1.16
1.98
7.8
7.0
104.4
104.5
mmol/l
0.14
373
3233
122
954
1.29
1.96
1.7
1.6
194.3
361.4
titre
—
7
44
108
833
1.31
1.93
2.3
2.8
—
—
—
0
0
38
242
1.58
1.92
1.6
1.4
1.2
1.3
promille
0.10
29
193
919
8520
1.11
1.88
3.6
3.2
7.8
7.7
mmol/l
0.10
762
7249
12
52
2.31
1.87
2.2
1.3
—
—
—
0
0
408
3609
1.15
1.85
3.0
2.6
23.1
23.7
%
0.34
357
3112
6
17
3.53
1.83
1.0
1.1
7.2
8.1
mmol/l
—
6
17
114
893
1.29
1.83
2.1
2.3
331.8
699.1
ug/l
0.87
107
835
57
401
1.43
1.82
1.1
1.1
4.5
4.0
u/ml
0.06
20
155
39
254
1.54
1.81
2.5
2.7
—
—
—
0
0
186
1544
1.22
1.80
2.3
3.4
34.1
55.6
u/ml
1.36
176
1494
572
5181
1.12
1.79
3.7
3.5
250.9
436.8
ng/l
1.23
399
3802
6
152
0.39
1.76
1.2
1.7
—
—
—
0
0
6
152
0.39
1.76
1.2
1.7
—
—
—
0
0
6
152
0.39
1.76
1.2
1.7
—
—
—
0
0
6
152
0.39
1.76
1.2
1.7
—
—
—
0
0
842
7800
1.10
1.75
1.8
1.6
1.4
1.4
mmol/l
0.30
689
6596
9
36
2.50
1.74
13.4
10.4
4.9
5.7
mmol/l
—
9
36
8
30
2.67
1.72
1.0
1.0
—
—
—
0
0
390
3458
1.14
1.72
7.1
6.3
1.0
1.0
mmol/l
0.22
366
3231
253
2172
1.18
1.71
2.3
2.3
8.4
7.5
ug/l
0.16
223
1945
74
553
1.35
1.68
1.4
1.6
—
—
—
0
0
105
825
1.28
1.67
1.3
1.4
275.0
290.5
ug/g
0.32
59
472
328
2882
1.15
1.65
1.9
1.7
—
—
—
0
0
899
8390
1.10
1.59
5.1
4.5
2.3
2.5
ug/l
0.34
799
7591
99
779
1.28
1.58
2.1
2.0
10.2
11.3
mg/l
0.74
93
727
324
2856
1.15
1.57
1.8
1.7
—
—
—
0
0
628
5766
1.11
1.55
1.7
1.6
83112360.1
37937813.3
pmol/l
0.61
527
4887
149
1231
1.22
1.55
2.1
2.0
39.4
38.7
u/l
0.15
128
1123
193
1636
1.19
1.54
1.5
1.3
23.3
30.5
iu/l
2.62
171
1397
508
4615
1.12
1.53
1.8
1.7
1187.6
1157.3
nmol/l
0.30
379
3563
221
1897
1.18
1.53
3.2
3.4
4.5
4.5
pmol/l
0.04
193
1693
651
5997
1.10
1.51
1.6
1.5
20.6
20.6
nmol/l
0.01
542
5210
104
829
1.26
1.50
1.1
1.1
3.3
4.4
u/ml
—
8
111
16
86
1.86
1.50
1.0
1.0
—
—
—
0
0
980
9205
1.09
1.50
2.9
3.5
2.3
2.4
mmol/l
0.68
851
8175
77
593
1.31
1.46
1.3
1.4
—
—
—
0
0
317
2808
1.14
1.45
2.2
2.6
1.8
1.8
%
0.28
277
2514
307
2715
1.14
1.44
3.5
4.1
7.5
24.7
ug/l
2.17
240
2171
5
123
0.41
1.36
1.0
1.9
—
—
—
0
0
5
123
0.41
1.36
1.0
1.9
—
—
—
0
0
373
3354
1.13
1.36
4.4
4.2
31.7
31.8
%
0.10
272
2339
5
124
0.40
1.36
1.0
1.9
—
—
—
0
0
78
609
1.29
1.36
4.0
5.5
2105.3
584.3
iu/ml
—
6
82
99
797
1.25
1.35
1.7
1.7
—
—
—
0
0
222
1929
1.16
1.34
1.4
1.3
421.8
217.7
u/ml
0.37
211
1779
48
349
1.38
1.34
1.4
1.6
69.0
59.6
%
0.94
25
216
489
4469
1.11
1.34
3.3
3.5
0.8
0.8
mmol/l
0.05
455
4199
131
1088
1.21
1.33
2.1
1.6
295.5
296.1
mu/l
0.01
122
993
9
42
2.15
1.33
6.9
5.1
—
—
—
0
0
0
41
0.00
1.31
0.0
2.2
—
—
—
0
0
33
225
1.47
1.31
2.1
2.5
590.6
718.3
e6/l
0.53
12
92
337
3023
1.13
1.29
8.5
7.5
1.0
1.1
mmol/l
0.20
271
2366
380
3435
1.12
1.28
2.1
2.0
—
—
—
0
0
338
3037
1.12
1.26
8.5
7.5
11.9
12.6
kpa
1.80
319
2908
15
254
0.59
1.25
1.3
1.5
—
—
—
0
0
15
254
0.59
1.25
1.3
1.5
—
—
—
0
0
15
254
0.59
1.25
1.3
1.5
—
—
—
0
0
28
187
1.50
1.23
2.7
2.7
40.9
41.7
%
0.06
14
62
113
934
1.22
1.23
2.6
1.8
—
—
—
0
0
337
3036
1.12
1.21
8.5
7.5
5.1
5.1
kpa
0.57
318
2907
167
1435
1.17
1.19
11.8
10.5
—
—
—
0
0
64
497
1.29
1.19
1.1
1.1
5.1
2.2
u/ml
0.59
15
119
728
6822
1.08
1.17
2.2
2.2
2.9
2.9
mg/l
0.01
620
5863
143
1218
1.18
1.15
5.5
4.0
24.1
24.2
mmol/l
0.25
127
1104
23
150
1.54
1.14
1.9
1.6
—
—
—
0
0
23
150
1.54
1.14
1.9
1.6
—
—
—
0
0
284
2544
1.13
1.14
9.4
8.3
122.4
122.8
g/l
0.13
274
2454
104
861
1.21
1.13
1.5
1.4
10.2
10.1
u/l
0.02
88
710
192
1678
1.15
1.12
7.3
7.0
24.8
24.5
mmol/l
0.46
182
1565
68
538
1.27
1.11
3.5
3.5
136.6
798.0
u/ml
0.77
61
500
67
530
1.27
1.10
1.6
1.7
—
—
—
0
0
57
442
1.29
1.09
1.1
1.1
5.3
2.6
u/ml
0.69
22
156
17
104
1.64
1.09
2.1
1.9
—
—
—
0
0
23
152
1.52
1.08
1.6
3.2
—
—
—
0
0
7
33
2.12
1.05
1.4
1.1
3.3
5.1
nmol/l
—
7
33
872
8264
1.07
1.05
4.3
4.0
12.8
8.2
mg/mmol
1.48
550
5279
21
138
1.52
1.02
1.0
1.7
—
—
—
0
0
337
3072
1.11
1.01
2.0
1.9
—
—
—
0
0
537
5003
1.09
1.01
1.5
1.5
—
—
—
0
0
95
791
1.21
1.00
1.2
1.1
—
—
—
0
0
7
35
2.00
1.00
1.0
1.5
—
—
—
0
0
60
476
1.26
0.99
1.1
1.1
4.4
10.3
au/ml
—
5
29
101
848
1.20
0.98
1.9
2.6
3.8
3.6
g/l
0.43
96
797
39
292
1.34
0.97
1.9
2.0
15.9
23.8
ug/l
1.07
39
287
109
924
1.19
0.96
1.8
1.7
1.2
1.2
g/l
0.39
104
881
12
198
0.60
0.95
2.0
1.5
—
—
—
0
0
9
51
1.77
0.94
3.1
2.2
1.2
1.2
mmol/l
—
9
51
42
320
1.32
0.94
2.2
1.9
4.7
5.2
umol/l
0.24
31
226
94
788
1.20
0.94
4.4
3.2
1.4
1.5
mg/l
0.29
89
738
6
27
2.22
0.93
1.3
1.3
—
—
—
0
0
47
368
1.28
0.88
1.0
1.1
0.2
0.3
u/ml
—
7
80
8
43
1.86
0.87
1.8
1.7
102.3
122.7
ng/l
—
8
43
58
467
1.25
0.87
3.4
2.7
3393.7
1714.0
u/ml
—
6
27
34
255
1.34
0.86
1.1
1.6
—
—
—
0
0
90
760
1.19
0.85
1.4
1.4
—
—
—
0
0
24
170
1.41
0.85
1.0
1.1
0.9
1.1
u/l
—
8
87
17
112
1.52
0.84
2.4
4.4
—
—
—
0
0
31
230
1.35
0.84
1.1
1.3
0.4
0.7
u/ml
0.27
11
94
88
743
1.19
0.84
3.8
3.6
1.6
2.4
ratio
—
7
62
26
188
1.39
0.83
1.2
1.6
—
—
—
0
0
13
81
1.61
0.81
1.3
1.2
—
—
—
0
0
36
276
1.31
0.80
2.5
5.8
5.9
7.4
mmol/l
4.51
25
232
90
766
1.18
0.80
3.8
3.6
34.2
63.5
mg/l
2.20
74
622
90
766
1.18
0.80
3.8
3.7
29.0
56.4
mg/l
1.56
72
624
13
200
0.65
0.79
1.5
1.9
—
—
—
0
0
42
330
1.28
0.79
1.2
1.4
185.5
289.2
pmol/l
3.40
33
261
55
447
1.23
0.78
1.3
1.2
—
—
—
0
0
16
234
0.68
0.77
1.4
1.5
11.8
12.5
umol/l
0.13
16
222
24
174
1.38
0.76
1.9
1.5
—
—
—
0
0
519
4893
1.07
0.75
3.0
2.8
0.7
0.7
ug/l
0.08
336
3063
90
771
1.17
0.75
1.7
1.9
3.1
5.0
iu/l
2.44
33
290
42
333
1.26
0.74
1.2
1.4
—
—
—
0
0
19
133
1.43
0.73
1.7
2.0
146.1
166.7
umol/l
—
8
73
7
40
1.75
0.71
1.0
1.2
—
—
—
0
0
37
291
1.27
0.70
1.2
1.2
—
—
—
0
0
5
26
1.92
0.70
1.0
1.1
—
—
—
0
0
5
26
1.92
0.70
1.0
1.1
—
—
—
0
0
15
101
1.49
0.70
1.3
1.5
15.3
15.5
pmol/l
0.03
15
91
10
61
1.64
0.68
3.1
2.1
16.6
17.1
umol/l
—
10
61
7
42
1.67
0.68
1.0
1.2
—
—
—
0
0
22
161
1.37
0.68
1.8
1.5
11.3
13.3
u/l
1.07
22
155
7
43
1.63
0.66
1.0
1.2
—
—
—
0
0
34
267
1.28
0.66
1.2
1.4
—
—
—
0
0
112
988
1.14
0.66
1.7
1.8
—
—
—
0
0
414
3895
1.07
0.65
1.8
1.8
1.6
1.5
%
1.50
359
3464
51
421
1.21
0.65
3.6
3.2
0.8
0.8
nmol/l
0.02
36
336
10
62
1.61
0.65
1.2
1.2
—
—
—
0
0
19
137
1.39
0.64
1.5
1.9
—
—
—
0
0
19
137
1.39
0.64
1.1
1.4
—
—
—
0
0
26
337
0.77
0.63
1.1
1.2
—
—
—
0
0
33
261
1.27
0.62
1.5
1.4
70122.6
85431.7
e6/l
0.10
22
179
16
113
1.42
0.61
2.7
2.6
47.8
144.6
au/ml
—
6
17
41
334
1.23
0.61
1.2
1.4
—
—
—
0
0
21
156
1.35
0.61
1.1
1.5
37.1
25.6
umol/l
0.76
21
147
13
88
1.48
0.60
1.0
1.2
89.8
93.1
%
—
6
48
19
139
1.37
0.60
2.1
1.3
29.2
30.8
nmol/l
0.05
19
116
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
37
299
1.24
0.59
1.2
1.2
58.8
60.5
u/l
0.06
27
205
41
336
1.22
0.58
1.2
1.4
—
—
—
0
0
13
89
1.46
0.58
1.0
1.1
85.3
88.7
%
—
6
48
6
35
1.72
0.57
1.0
1.0
—
—
—
0
0
72
623
1.16
0.57
1.1
1.1
1.0
1.5
u/ml
0.35
28
223
42
346
1.22
0.57
1.2
1.4
—
—
—
0
0
95
839
1.14
0.57
2.8
2.5
0.5
1.1
g/l
1.52
81
743
27
211
1.28
0.57
1.3
1.3
—
—
—
0
0
19
141
1.35
0.56
1.1
1.3
—
—
—
0
0
6
37
1.62
0.55
1.2
1.1
—
—
—
0
0
96
851
1.13
0.55
1.1
1.1
—
—
—
0
0
29
230
1.26
0.55
1.0
1.1
—
—
—
0
0
6
39
1.54
0.53
1.0
1.0
—
—
—
0
0
106
1181
0.89
0.52
1.7
1.7
2.8
4.0
mg/l
0.98
76
813
6
96
0.62
0.52
1.2
1.6
8.8
8.6
ug/l
—
6
96
100
894
1.12
0.51
3.0
2.4
9.8
10.3
g/l
0.62
81
774
28
224
1.25
0.50
1.1
1.3
2.5
2.1
mmol/l
0.35
23
211
162
1488
1.09
0.50
1.7
1.6
—
—
—
0
0
56
482
1.16
0.50
1.4
1.4
28.1
27.2
u/l
0.07
49
406
30
243
1.24
0.49
1.2
1.2
32.7
43.5
mg/l
1.87
24
200
26
207
1.26
0.49
1.8
1.6
—
—
—
0
0
41
344
1.19
0.49
1.2
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
94
841
1.12
0.48
3.6
3.3
0.4
0.3
u/ml
0.71
59
477
210
1955
1.08
0.48
5.3
3.9
101.1
88.0
ng/l
0.89
189
1724
29
235
1.24
0.48
1.1
1.1
230.3
288.6
mg/l
1.99
23
201
120
1090
1.10
0.48
1.8
1.9
—
—
—
0
0
20
256
0.78
0.48
1.2
1.4
126.4
179.3
pmol/l
—
6
78
68
597
1.14
0.47
1.3
2.1
0.9
0.8
nmol/l
0.80
63
498
55
634
0.87
0.47
1.2
1.2
—
—
—
0
0
107
967
1.11
0.47
2.9
2.4
3.6
3.8
g/l
0.89
71
705
107
968
1.11
0.46
2.9
2.4
7.2
7.3
g/l
0.29
76
743
107
968
1.11
0.46
2.9
2.4
—
—
—
0
0
48
411
1.17
0.46
1.1
1.1
—
—
—
0
0
59
675
0.87
0.46
1.5
1.6
—
—
—
0
0
7
50
1.40
0.45
2.1
1.7
—
—
—
0
0
26
210
1.24
0.45
1.0
1.0
—
—
—
0
0
83
743
1.12
0.44
3.0
2.4
0.0
0.0
g/l
1.71
75
697
35
293
1.20
0.44
1.0
1.1
—
—
—
0
0
231
2169
1.07
0.44
2.3
2.3
12.7
13.0
nmol/l
0.22
204
1945
49
423
1.16
0.43
1.6
1.4
—
—
—
0
0
8
56
1.43
0.42
1.0
1.1
—
—
—
0
0
123
1128
1.09
0.42
1.7
1.8
1.6
1.6
g/l
0.27
104
977
87
784
1.11
0.42
1.3
1.3
7.8
7.0
u/ml
—
6
79
122
1119
1.09
0.42
1.8
1.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
36.1
—
0
16
0
16
0.00
0.41
0.0
1.1
—
8.9
—
0
16
0
16
0.00
0.41
0.0
1.1
—
22.3
—
0
16
65
577
1.13
0.40
3.0
3.3
18.2
25.2
mg/l
1.19
40
359
22
177
1.24
0.40
1.4
3.2
30.1
26.0
mu/l
0.18
22
171
0
18
0.00
0.40
0.0
1.0
—
0.2
—
0
12
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
105
960
1.10
0.39
2.8
3.5
251.2
1634.5
u/ml
0.71
95
824
67
598
1.12
0.39
3.2
3.0
31.2
37.1
umol/l
1.51
59
512
43
495
0.87
0.38
1.6
1.7
—
—
—
0
0
14
107
1.31
0.37
1.1
1.4
—
—
—
0
0
14
107
1.31
0.37
1.1
1.4
—
—
—
0
0
5
37
1.35
0.37
2.2
2.0
—
—
—
0
0
62
554
1.12
0.36
1.6
1.5
—
—
—
0
0
5
80
0.62
0.35
1.0
1.8
11.0
49.6
u/l
—
5
75
23
277
0.83
0.35
4.9
5.0
34.2
81.1
u/ml
—
7
85
17
135
1.26
0.35
1.3
1.5
28.8
29.7
umol/l
0.18
17
128
39
339
1.15
0.34
1.2
1.4
—
—
—
0
0
55
490
1.12
0.34
1.5
1.5
—
—
—
0
0
99
912
1.09
0.33
3.0
2.5
3.0
3.1
g/l
0.99
74
725
13
100
1.30
0.33
1.0
1.3
—
—
—
0
0
13
166
0.78
0.33
1.0
1.1
—
—
—
0
0
6
47
1.28
0.32
1.2
1.6
—
—
—
0
0
12
92
1.31
0.31
1.0
1.2
—
—
—
0
0
26
220
1.18
0.31
2.8
2.3
659.2
611.7
ml
0.33
20
153
92
849
1.09
0.31
1.1
1.1
—
—
—
0
0
42
371
1.13
0.30
1.6
1.4
—
—
—
0
0
43
484
0.89
0.30
1.0
1.1
16540.0
20893.6
iu/ml
0.06
11
112
24
282
0.85
0.29
1.9
1.5
1058.1
2357.2
e6/l
1.78
17
205
243
2323
1.05
0.29
2.6
2.5
65.6
68.8
ml/min/173m2
0.57
96
884
18
148
1.22
0.29
2.4
1.8
—
—
—
0
0
8
108
0.74
0.29
1.0
1.5
—
—
—
0
0
145
1367
1.06
0.28
12.0
9.9
24.1
24.4
mmol/l
0.46
136
1289
29
334
0.87
0.28
1.1
1.1
—
—
—
0
0
29
251
1.16
0.28
1.2
1.3
—
—
—
0
0
23
195
1.18
0.28
1.1
1.1
1.1
1.0
ratio
—
8
70
43
481
0.89
0.28
1.5
1.4
0.4
0.3
nmol/l
0.15
30
373
10
76
1.32
0.28
1.0
1.1
—
—
—
0
0
10
76
1.32
0.28
1.0
1.1
—
—
—
0
0
29
252
1.15
0.27
3.2
4.1
—
—
—
0
0
86
798
1.08
0.26
1.3
1.3
23.1
8.5
u/ml
—
10
127
38
338
1.13
0.26
1.2
1.4
3.7
3.7
ug/l
0.03
32
300
12
95
1.26
0.26
1.9
3.1
—
—
—
0
0
82
761
1.08
0.26
3.0
2.3
38.5
37.8
g/l
0.63
68
673
23
197
1.17
0.25
1.8
1.4
293.9
352.8
u/l
0.41
23
190
61
663
0.92
0.24
1.6
1.6
—
—
—
0
0
22
254
0.87
0.23
2.3
3.4
63.0
56.5
%
0.77
16
171
61
562
1.09
0.23
1.5
1.4
112.8
117.7
u/ml
0.19
24
111
52
476
1.09
0.23
1.1
1.1
—
—
—
0
0
12
97
1.24
0.23
1.7
2.0
112.9
160.6
%
1.66
12
90
19
162
1.17
0.22
1.3
1.4
1.1
1.3
nmol/l
0.49
11
130
167
1597
1.05
0.22
1.3
1.4
—
—
—
0
0
682
6688
1.02
0.22
4.3
3.9
22.0
21.5
%
0.36
324
3002
5
41
1.22
0.22
1.0
1.0
—
—
—
0
0
5
41
1.22
0.22
1.2
1.4
2300007.3
886674.9
nmol/l
—
5
30
5
42
1.19
0.21
1.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
4.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
(46236287) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay
0
12
0.00
0.21
0.0
1.2
—
3425.7
—
0
7
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
4.4
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
14.2
—
—
—
0
0
26
230
1.13
0.20
1.0
1.1
—
—
—
0
0
70
654
1.07
0.20
2.9
2.5
123.8
116.2
ug/min
0.05
43
401
23
202
1.14
0.20
1.5
1.2
—
—
—
0
0
6
49
1.22
0.20
1.0
1.4
—
—
—
0
0
162
1554
1.04
0.20
1.1
1.0
—
—
—
0
0
26
231
1.13
0.19
1.0
1.1
—
—
—
0
0
91
961
0.95
0.19
1.7
1.6
0.1
6.8
iu/ml
0.53
23
187
72
676
1.07
0.19
1.5
1.7
6233.6
12658.4
e6/l
2.03
57
487
16
137
1.17
0.18
1.0
1.0
—
—
—
0
0
69
647
1.07
0.18
1.2
1.3
43.9
49.8
u/ml
—
9
69
89
842
1.06
0.18
1.7
2.4
185.3
186.9
%
0.06
84
800
13
109
1.19
0.18
1.8
1.8
—
—
—
0
0
29
321
0.90
0.18
1.2
1.6
—
—
—
0
0
7
59
1.19
0.18
1.1
1.1
—
—
—
0
0
56
600
0.93
0.18
1.3
1.2
280.1
273.7
u/ml
0.07
35
368
26
233
1.12
0.17
1.0
1.1
—
—
—
0
0
26
233
1.12
0.17
1.0
1.1
—
—
—
0
0
22
195
1.13
0.17
1.2
1.2
—
—
—
0
0
38
349
1.09
0.17
1.1
1.1
—
—
—
0
0
23
205
1.12
0.17
1.5
1.2
—
—
—
0
0
5
68
0.73
0.17
1.0
1.1
—
—
—
0
0
26
234
1.11
0.16
1.0
1.1
—
—
—
0
0
268
2609
1.03
0.16
2.5
2.3
0.2
0.2
g/l
0.87
257
2446
73
690
1.06
0.16
3.2
2.4
0.0
0.0
g/l
0.00
67
646
14
120
1.17
0.16
2.5
2.3
—
—
—
0
0
8
72
1.11
0.16
1.1
1.1
—
—
—
0
0
13
111
1.17
0.15
1.0
1.2
—
—
—
0
0
303
3103
0.97
0.15
1.8
1.7
—
—
—
0
0
9
78
1.15
0.15
1.0
1.1
—
—
—
0
0
90
943
0.95
0.15
1.5
1.3
—
—
—
0
0
27
296
0.91
0.14
1.2
1.7
—
—
—
0
0
21
188
1.12
0.14
2.0
1.6
8.2
6.5
u/l
0.22
13
93
49
459
1.07
0.14
1.1
1.1
—
—
—
0
0
175
1697
1.03
0.14
11.5
9.2
93.8
94.0
%
0.14
175
1691
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
17
150
1.13
0.14
1.0
1.1
—
—
—
0
0
47
440
1.07
0.14
1.0
1.1
5.1
3.1
u/ml
0.23
20
212
101
969
1.04
0.14
1.3
1.3
160.3
222.5
miu/ml
1.32
51
471
10
84
1.19
0.14
1.0
1.1
—
—
—
0
0
10
84
1.19
0.14
1.0
1.1
—
—
—
0
0
478
4854
0.98
0.13
2.8
3.0
2.5
2.4
mmol/l
0.61
412
4265
13
114
1.14
0.11
1.3
1.2
—
—
—
0
0
31
288
1.08
0.11
1.4
1.2
—
—
—
0
0
68
653
1.04
0.10
1.2
1.3
3.6
3.7
mmol/l
0.46
60
613
52
496
1.05
0.10
1.2
1.2
2.1
3.0
u/ml
0.52
20
162
5
44
1.14
0.10
1.2
1.5
—
—
—
0
0
47
493
0.95
0.09
1.1
1.1
—
—
—
0
0
13
145
0.90
0.09
1.0
1.1
—
—
—
0
0
20
217
0.92
0.09
1.7
1.8
—
—
—
0
0
22
204
1.08
0.08
1.6
2.1
1.7
1.7
u/field
0.01
11
90
12
107
1.12
0.08
1.0
1.0
—
—
—
0
0
7
65
1.08
0.08
1.6
1.1
—
—
—
0
0
23
246
0.93
0.08
1.9
1.4
38308.3
94232.0
e6/l
0.82
15
149
6
70
0.86
0.07
1.0
1.3
—
—
—
0
0
114
1113
1.03
0.07
1.4
1.4
—
—
—
0
0
52
540
0.96
0.07
1.4
1.3
—
—
—
0
0
52
540
0.96
0.07
1.4
1.3
—
—
—
0
0
11
122
0.90
0.07
1.2
1.6
—
—
—
0
0
11
122
0.90
0.07
1.2
1.6
—
—
—
0
0
14
128
1.09
0.06
2.4
3.3
—
—
—
0
0
19
177
1.07
0.06
1.0
1.2
—
—
—
0
0
15
162
0.93
0.06
1.1
1.3
—
—
—
0
0
50
484
1.03
0.05
1.2
1.2
2.5
4.9
u/ml
2.00
22
209
16
149
1.07
0.05
1.3
1.1
58.5
82.5
u/l
1.94
16
123
16
149
1.07
0.05
1.3
1.1
7.9
23.5
u/l
4.61
16
115
30
288
1.04
0.04
1.0
1.1
—
—
—
0
0
10
91
1.10
0.04
1.1
1.2
—
—
—
0
0
10
91
1.10
0.04
1.3
1.2
—
—
—
0
0
125
1268
0.99
0.04
1.5
1.5
—
—
—
0
0
203
2051
0.99
0.04
2.4
2.8
196.5
177.4
ng/l
0.22
178
1861
330
3322
0.99
0.03
6.5
6.4
—
—
—
0
0
73
718
1.02
0.03
1.2
1.2
—
—
—
0
0
39
381
1.02
0.02
1.7
1.6
—
—
—
0
0
13
137
0.95
0.01
1.2
1.2
—
—
—
0
0
38
388
0.98
0.01
1.7
1.5
—
—
—
0
0
30
307
0.98
0.01
1.7
1.7
—
—
—
0
0
40
393
1.02
0.01
1.2
1.3
—
—
—
0
0
66
653
1.01
0.01
1.3
1.5
954.4
1427.8
e6/l
0.31
54
536
66
653
1.01
0.01
1.3
1.4
11.7
32.4
e6/l
0.93
53
512
41
416
0.99
0.00
3.8
3.4
0.6
1.3
%
2.73
34
332
12
118
1.02
0.00
1.3
1.1
—
—
—
0
0
22
225
0.98
0.00
1.1
1.1
—
—
—
0
0
68
678
1.00
0.00
1.4
1.4
—
—
—
0
0
46
455
1.01
0.00
1.4
1.5
—
—
—
0
0
52
525
0.99
0.00
1.5
1.7
—
—
—
0
0
68
675
1.01
0.00
1.4
1.4
—
—
—
0
0
83
835
0.99
0.00
1.4
1.4
—
—
—
0
0
40
399
1.00
0.00
1.3
1.5
—
—
—
0
0
68
679
1.00
0.00
1.4
1.4
—
—
—
0
0
73
734
0.99
0.00
1.5
1.5
—
—
—
0
0
68
676
1.01
0.00
1.4
1.4
—
—
—
0
0
60
596
1.01
0.00
1.6
1.5
—
—
—
0
0
21
206
1.02
0.00
1.1
1.1
—
—
—
0
0
16
157
1.02
0.00
8.3
6.7
29.6
57.3
u/ml
—
5
42
23
227
1.01
0.00
1.2
1.1
—
60.6
—
0
7
17
167
1.02
0.00
1.5
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
13
130
1.00
0.00
1.0
1.2
1997.8
1495.3
miu/ml
1.26
13
130
22
220
1.00
0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
9.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
6.0
—
0.3
—
0
5
7
73
0.96
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
1.2
—
0
6
0
8
0.00
0.00
0.0
9.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_APPENDOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_APPENDOTH | 1.152 [0.93, 1.43] | 0.2 |
| Birth year | 0.992 [0.98, 1.0] | 0.062 |
During the follow-up period (1.1.1998 — 31.12.2019), 155 out of 3277 females with K11_APPENDOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_APPENDOTH | 1.066 [0.88, 1.3] | 0.52 |
| Birth year | 0.991 [0.98, 1.0] | 0.089 |
During the follow-up period (1.1.1998 — 31.12.2019), 202 out of 3197 males with K11_APPENDOTH died.
Mortality risk
Mortality risk for people of age
years, who have K11_APPENDOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.088% | 0.285% |
| 5 | 0.562% | 1.552% |
| 10 | 1.442% | 3.661% |
| 15 | 2.692% | 6.828% |
| 20 | 4.667% | 11.537% |
Relationships between endpoints
↥Index endpoint: K11_APPENDOTH – Other appendicitis
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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