appendicitis: Acute inflammation of the vermiform appendix.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3685 |
4. Check minimum number of eventsNone |
3685 |
5. Include endpointsNone |
3685 |
6. Filter based on genotype QC (FinnGen only) |
3571 |
Control definitions (FinnGen only)
- Control exclude
- K11_APPENDIX
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other appendicitis
based on the number of shared cases.
Similar with more cases:
- Appendicitis, broad definition
- Diseases of appendix
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 30807 | 15923 | 14710 |
| Only index persons | 27597 | 14579 | 13018 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.43 | 0.46 | 0.41 |
| Only index persons | 0.52 | 0.54 | 0.50 |
| Median age at first event (years) | |||
| Whole population | 26.65 | 26.67 | 26.39 |
| Only index persons | 25.39 | 25.68 | 25.07 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3571 | 2106 | 1465 |
| Unadjusted period prevalence (%) | 0.72 | 0.75 | 0.67 |
| Median age at first event (years) | 28.62 | 27.41 | 30.35 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3685
- Matched controls
- 36850
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
6421
FHL
Appendicectomy
30.3
307.7
784
326
5410X
ICD-9 Finland
Appendicitis, unqualified[APPENDICITIS NUD]
+∞
307.7
659
*
K36
ICD-10 Finland
Other appendicitis
1831.7
307.7
323
*
JEA01
NOMESCO Finland
Laparoscopic appendectomy
99.9
307.7
711
88
54199
ICD-8 Finland
Appendicitis, unqualified
+∞
307.7
1285
*
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
371.8
307.7
593
19
K37
ICD-10 Finland
Unspecified appendicitis
727.6
307.7
885
16
54200
ICD-8 Finland
Other appendicitis, Appendicitis chronica
+∞
233.9
222
*
JEA00
NOMESCO Finland
Appendectomy
6.8
144.5
233
361
54208
ICD-8 Finland
Other appendicitis
+∞
112.0
107
*
5428X
ICD-9 Finland
Other appendicitis[APPENDICITIS ALIA DEFINITA]
+∞
107.8
103
*
K35.1
ICD-10 Finland
Acute appendicitis with peritoneal abscess
+∞
105.7
101
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
87.1
1457
9026
JN3AD
NOMESCO Finland
Abdominal CT examination
2.7
85.7
520
2107
K35.0
ICD-10 Finland
Acute appendicitis with generalized peritonitis
+∞
79.5
76
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.7
68.7
422
1711
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
64.1
924
5325
P01AB01
ATC
metronidazole; oral, rectal
1.8
56.4
1508
10448
54003
ICD-8 Finland
Acute appendicitis, Cum abscessu
+∞
49.1
47
*
5420A
ICD-9 Finland
Other appendicitis[APPENDICITIS CHRONICA]
+∞
49.1
47
*
ZXD05
NOMESCO Finland
Urgent procedure
1.7
44.0
1048
6925
5409X
ICD-9 Finland
Acute appendicitis, Without mention of peritonitis
+∞
39.6
38
*
54099
ICD-8 Finland
Acute appendicitis, Without mention of peritonitis
+∞
39.6
38
*
WX402
NOMESCO Finland
General anaesthesia
1.7
37.5
783
4955
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
34.3
882
5884
N02BE01
ATC
paracetamol; systemic, rectal
1.7
28.0
3158
28667
WX704
NOMESCO Finland
Intubation
2.1
27.3
288
1456
A02BC05
ATC
esomeprazole; systemic
1.5
25.7
1377
10670
N02AX02
ATC
tramadol; systemic, rectal
1.5
25.6
1434
11203
5401A
ICD-9 Finland
Acute appendicitis, With peritoneal abscess
+∞
25.0
24
*
J01DB01
ATC
cefalexin; oral
1.5
24.4
2920
26233
R10.0
ICD-10 Finland
Acute abdomen
2.8
23.6
123
456
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
22.1
586
3891
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
2.7
20.8
113
428
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
20.6
1505
12190
54201
ICD-8 Finland
Other appendicitis, Appendicitis recidivans
+∞
19.8
19
*
D88
ICPC
Appendicitis
105.6
19.6
21
*
K35
ICD-10 Finland
Acute appendicitis
28.0
18.7
25
9
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
18.6
407
2570
M01AB05
ATC
diclofenac; systemic, rectal
1.4
18.6
2299
20138
J01AA02
ATC
doxycycline; systemic
1.4
18.4
2684
24142
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
18.0
863
6459
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
17.5
1165
9223
UJF32
NOMESCO Finland
Coloscopy
1.4
16.9
783
5818
N03AX16
ATC
[U] pregabalin
1.4
16.7
739
5438
D01
ICPC
Abdominal pain/cramps general
1.6
16.7
365
2303
ZXE00
NOMESCO Finland
One hour or less
1.4
16.2
1223
9852
M03BX02
ATC
tizanidine; oral
1.3
16.0
2158
18936
A02BC02
ATC
pantoprazole; systemic
1.3
15.9
2254
19914
JAH01
NOMESCO Finland
Laparoscopy
2.1
14.9
144
705
H02AB06
ATC
prednisolone; systemic
1.3
14.7
1509
12669
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
14.5
654
4821
SPAT1263
SPAT
Sampling
1.3
14.3
1279
10522
99850
ICD-8 Finland
Other complications of surgical procedures, Postoperative wound infection
5.3
13.7
27
51
J01MA02
ATC
ciprofloxacin; systemic
1.3
13.7
1176
9605
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.9
13.3
170
918
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.5
13.2
498
3543
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
12.1
3203
30295
R51.80
ICD-10 Finland
Headache
1.4
12.1
483
3473
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
12.1
324
2146
M79.6
ICD-10 Finland
Pain in limb
1.3
12.0
1322
11119
M01AE02
ATC
naproxen; oral, rectal
1.3
12.0
1857
16311
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
2.1
11.9
107
511
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
11.7
1077
8838
A02BC01
ATC
omeprazole; systemic
1.3
11.7
794
6242
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
11.6
1616
13988
5421A
ICD-9 Finland
Other appendicitis[APPENDICITIS RECIDIVANS]
+∞
11.5
11
*
A03FA02
ATC
cisapride; oral, rectal
1.7
11.4
208
1252
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
11.3
1336
11318
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
11.1
547
4079
A02BC03
ATC
lansoprazole; oral
1.3
11.1
858
6866
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
11.0
2394
21804
Y0599
ICD-8 Finland
Investigation of digestive system
2.9
11.0
51
179
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
11.0
1355
11527
D37.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Appendix
10.6
10.8
20
19
AA1AD
NOMESCO Finland
CT of head and brain
1.3
10.7
740
5825
J01MA12
ATC
levofloxacin; systemic
1.4
10.6
518
3854
54191, ,
ICD-8 Finland
+∞
10.4
10
*
M54.5
ICD-10 Finland
Low back pain
1.3
10.3
1123
9395
R51
ICD-10 Finland
Headache
1.7
9.9
170
1007
R03AC02
ATC
salbutamol; inhalant
1.2
9.7
1767
15663
UKC02
NOMESCO Finland
Cystoscopy
1.4
9.5
402
2914
M01AH01
ATC
celecoxib; oral
1.4
9.2
509
3865
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
9.2
824
6707
M01AH05
ATC
etoricoxib; oral
1.2
9.0
2070
18751
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
9.0
732
5878
J01FA10
ATC
azithromycin; systemic
1.2
8.8
1892
16996
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.4
8.8
360
2598
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
8.7
627
4947
J02AC01
ATC
fluconazole; systemic
1.2
8.7
1248
10734
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
8.4
1680
14946
B01AB05
ATC
enoxaparin; parenteral
1.3
8.4
885
7337
D06
ICPC
Abdominal pain localized other
1.5
8.4
239
1605
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
8.4
259
1769
J01EA01
ATC
trimethoprim; systemic
1.3
8.4
731
5921
54091
ICD-8 Finland
Acute appendicitis, Gangraenosa, peritonitide non indicata
+∞
8.3
8
*
54100, ,
ICD-8 Finland
+∞
8.3
8
*
G44.2
ICD-10 Finland
Tension-type headache
1.4
8.3
403
2992
J01FF01
ATC
clindamycin; systemic
1.3
8.2
804
6602
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
8.2
1807
16224
J01MA14
ATC
moxifloxacin; systemic
1.5
8.2
249
1695
N05BA04
ATC
oxazepam; oral
1.3
8.2
749
6101
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.4
8.1
326
2341
R06.0
ICD-10 Finland
Dyspnoea
1.3
8.1
732
5952
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.7
8.0
158
972
XKD00
NOMESCO Finland
Uroflowmetry
1.4
8.0
367
2699
N05BA01
ATC
diazepam; systemic, rectal
1.4
8.0
368
2710
R50.9
ICD-10 Finland
Fever, unspecified
1.4
7.9
411
3085
K30
ICD-10 Finland
Functional dyspepsia
1.4
7.9
317
2280
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
2.5
7.7
47
191
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
1.8
7.7
103
569
N06AA09
ATC
amitriptyline; systemic
1.5
7.6
260
1812
K66.0
ICD-10 Finland
Peritoneal adhesions
4.0
7.6
21
53
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.4
7.5
365
2709
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
7.5
550
4346
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
7.5
323
2350
N06AX11
ATC
mirtazapine; oral
1.2
7.5
1011
8608
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.4
7.4
276
1955
J01DA01
ATC
[U] cefalexin
1.2
7.4
1990
18142
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
7.4
749
6170
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
1.8
7.4
115
665
A02BA04
ATC
nizatidine; systemic
1.5
7.4
194
1281
J01DA06
ATC
[U] cefuroxime
1.4
7.4
415
3156
T81.2
ICD-10 Finland
Accidental puncture and laceration during a procedure, not elsewhere classified
2.9
7.4
34
120
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
1.9
7.3
84
441
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
7.3
661
5369
7231A
ICD-9 Finland
Other disorders of cervical region, Cervicalgia
3.1
7.3
29
94
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.4
7.2
287
2060
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.3
7.2
528
4174
Z25.1
ICD-10 Finland
Need for immunization against influenza
1.6
7.1
149
933
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.3
7.1
783
6512
UJF30
NOMESCO Finland
Ileoscopy through colon
1.4
7.1
279
1998
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.4
7.0
276
1975
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
2.7
7.0
35
129
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.4
7.0
318
2336
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
2.3
7.0
49
213
S06.0
ICD-10 Finland
Concussion
1.4
7.0
290
2097
G47.3
ICD-10 Finland
Sleep apnoea
1.3
6.9
670
5484
R52.9
ICD-10 Finland
Pain, unspecified
1.4
6.9
268
1917
1220
FHL
Arthroscopy
1.7
6.9
110
642
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.8
6.8
97
546
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
1.8
6.8
91
504
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
2.2
6.8
51
229
K38.9
ICD-10 Finland
Disease of appendix, unspecified
40.1
6.8
8
*
N03AX12
ATC
[U] gabapentin; oral
1.3
6.7
463
3625
J01FA09
ATC
clarithromycin; systemic
1.2
6.7
956
8169
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
6.7
574
4626
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
6.6
829
6985
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
6.6
398
3056
J11.1
ICD-10 Finland
Influenza with other respiratory manifestations, virus not identified
2.1
6.6
61
297
XFE00
NOMESCO Finland
Epicardial ultrasonography
2.1
6.6
57
271
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.4
6.6
362
2744
R52.2
ICD-10 Finland
Other chronic pain
1.7
6.6
105
613
WX725
NOMESCO Finland
Noninvasive ventilation
1.6
6.6
147
937
R03BA05
ATC
fluticasone; inhalant
1.3
6.5
513
4091
N06AB10
ATC
escitalopram; oral
1.3
6.5
610
4974
A01AB09
ATC
miconazole; local oral
1.5
6.5
218
1517
J01CE02
ATC
phenoxymethylpenicillin; oral
1.2
6.5
2234
20726
M02AA07
ATC
piroxicam; topical
1.2
6.5
1022
8824
C07AB07
ATC
bisoprolol; oral
1.2
6.4
1335
11832
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.2
6.4
766
6423
R42
ICD-10 Finland
Dizziness and giddiness
1.3
6.4
595
4846
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.4
6.3
231
1633
C01DA14
ATC
isosorbide mononitrate; oral
1.4
6.3
311
2317
J01FA06
ATC
roxithromycin; oral
1.2
6.3
1215
10689
C01CA24
ATC
epinephrine; parenteral
1.5
6.3
183
1237
54190, ,
ICD-8 Finland
+∞
6.2
6
*
K38.8
ICD-10 Finland
Other specified diseases of appendix
+∞
6.2
6
*
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.4
6.2
312
2331
N06AX21
ATC
duloxetine; oral
1.4
6.2
342
2593
Z13.5
ICD-10 Finland
Special screening examination for eye and ear disorders
2.9
6.1
27
93
M01AX17
ATC
nimesulide; oral
1.3
6.1
651
5383
JF2BD
NOMESCO Finland
Extensive colon CT
3.0
6.1
26
88
N05CF01
ATC
zopiclone; oral
1.2
6.1
902
7730
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.4
6.0
306
2290
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
2.5
6.0
36
146
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1307
8958
1.71
49.04
2.6
2.6
58.20
59.84
u/l
0.11
1231
8304
1883
14922
1.54
34.81
5.4
6.3
10.85
11.20
umol/l
0.72
1813
14193
1638
12659
1.53
33.58
12.4
13.4
1.23
1.22
inr
0.05
572
3704
1395
10445
1.54
32.91
3.7
3.4
31.56
48.75
ng/l
1.75
889
6667
2228
18957
1.44
24.75
4.4
4.1
1321.15
1936.86
e6/l
0.19
27
256
2570
22673
1.44
21.91
7.4
7.6
75.92
77.05
u/l
0.87
2443
21485
1988
16783
1.40
21.68
4.9
4.7
6.77
6.65
mmol/l
1.29
1892
15670
1022
7705
1.45
21.05
3.1
3.0
0.36
0.41
e6/l
0.27
777
5816
1670
13748
1.39
20.82
2.6
2.5
—
—
—
0
0
1390
11196
1.39
19.29
3.7
3.6
—
—
—
0
0
1088
8418
1.41
19.07
3.1
3.1
75.73
86.04
e6/l
0.16
836
6429
791
5803
1.46
18.42
2.4
2.5
6.67
5.90
e6/l
0.68
706
5205
1738
14596
1.36
18.24
3.6
3.5
0.00
0.00
estimate
1.47
410
2554
1716
14448
1.35
17.41
5.0
4.7
0.00
0.00
estimate
0.80
421
2660
1715
14469
1.35
17.03
3.6
3.5
0.00
0.00
estimate
1.23
436
2783
3284
30985
1.55
15.03
16.4
14.5
139.55
139.71
mmol/l
3.57
3231
30243
1977
17219
1.32
14.93
8.5
9.2
4.60
4.00
e9/l
16.25
1756
15085
3229
30384
1.51
14.67
15.3
13.1
25.52
22.30
mg/l
5.34
2773
23718
3289
31101
1.54
14.25
16.5
14.6
3.96
3.96
mmol/l
0.03
3233
30296
962
7646
1.35
13.39
3.8
3.8
0.01
0.00
estimate
0.20
401
2584
1214
10002
1.32
13.15
3.7
3.5
97.24
94.94
e6/l
0.03
897
6964
3075
28798
1.41
13.06
13.3
11.9
84.11
84.07
ml/min/173m2
0.03
2595
23803
194
1123
1.77
12.19
2.5
2.3
6877.26
4829.22
u/l
0.35
60
451
2320
21033
1.28
11.19
3.2
3.1
48.11
46.21
u/l
0.40
2211
19800
1035
8520
1.30
10.83
2.1
2.1
240.95
220.93
u/l
0.19
967
8045
291
1940
1.54
10.51
1.7
1.7
—
—
—
0
0
2421
22149
1.27
10.41
4.3
4.0
11.71
11.28
mm/h
0.78
2255
20655
857
6974
1.30
9.60
2.3
2.2
—
—
—
0
0
567
4388
1.35
9.03
2.7
2.8
2.63
2.66
e6/l
0.03
273
2352
2824
26574
1.27
8.29
17.5
15.6
14.61
14.92
%
0.89
2782
26091
1498
13225
1.22
7.96
10.8
9.2
0.00
0.00
e9/l
0.04
1269
10813
315
2258
1.43
7.95
4.0
4.0
1.23
1.23
mmol/l
0.09
281
1971
2918
27611
1.27
7.91
5.7
5.3
39.54
39.29
mmol/mol
0.76
2715
25839
2252
20751
1.22
7.65
3.2
3.1
—
—
—
0
0
589
4715
1.30
7.29
2.6
2.6
1.25
1.03
e6/l
0.32
292
2658
1564
13949
1.21
7.29
7.2
6.6
1.22
1.21
mmol/l
1.00
1281
11926
1619
14514
1.21
7.08
6.5
6.2
28.39
28.35
%
0.06
1540
13661
1519
13542
1.21
7.03
6.5
6.2
0.68
0.69
%
0.18
1433
12643
1573
14081
1.20
6.94
6.7
6.4
8.43
8.50
%
0.40
1491
13218
1598
14326
1.20
6.94
6.2
6.0
57.14
56.95
%
0.25
1521
13463
2507
23452
1.22
6.88
4.3
4.0
14.63
14.66
pmol/l
0.19
2294
21573
124
748
1.68
6.86
1.7
1.7
—
—
—
0
0
2937
27952
1.25
6.72
5.0
4.6
3.05
2.12
mu/l
0.47
2709
25902
1559
13991
1.20
6.58
6.5
6.1
2.93
2.87
%
0.48
1479
13105
1418
12628
1.20
6.48
6.4
5.9
1.22
1.21
mmol/l
0.83
1298
11601
702
5829
1.25
6.39
1.5
1.5
—
—
—
0
0
1710
15509
1.19
6.33
6.4
6.2
0.20
0.19
e9/l
1.22
1559
13705
376
2883
1.34
6.32
3.6
3.2
—
—
—
0
0
791
6665
1.24
6.30
1.6
1.7
1.22
1.11
mg/l
0.35
607
5055
233
1667
1.42
5.99
3.1
3.4
5.13
5.17
kpa
0.30
223
1591
907
7793
1.22
5.94
2.6
2.5
2049.74
4134.14
umol/l
1.44
800
6953
115
709
1.64
5.90
1.2
1.3
—
—
—
0
0
222
1581
1.43
5.86
3.0
3.4
1.84
1.79
mmol/l
0.09
165
1178
99
588
1.70
5.85
4.1
3.7
56.19
57.49
%
0.48
99
588
1694
15423
1.18
5.81
6.3
6.0
2.04
1.91
e9/l
0.96
1545
13750
873
7493
1.22
5.75
3.7
3.9
90.69
92.11
%
0.95
858
7293
651
5443
1.24
5.51
1.3
1.3
23.96
30.74
iu/ml
1.33
216
1785
795
6820
1.21
5.21
1.3
1.3
1.23
1.83
u/ml
1.58
219
1865
93
563
1.67
5.17
2.8
2.6
17.29
16.37
%
1.35
46
290
842
7273
1.20
5.13
3.0
2.9
1254.50
1182.96
ng/l
0.13
701
6126
354
2777
1.30
5.08
2.5
2.5
32.67
56.42
u/l
0.78
307
2414
3349
32588
1.30
5.05
10.7
10.0
27.00
27.02
u/l
0.02
3250
31584
154
1058
1.48
4.95
2.4
2.0
1.02
2.09
ug/l
1.60
133
948
278
2125
1.33
4.81
2.3
2.4
25.87
24.02
au/ml
0.11
25
184
257
1942
1.35
4.80
3.5
3.1
4.65
4.69
kpa
0.11
252
1873
291
2254
1.32
4.60
4.6
4.0
0.50
0.67
%
1.16
101
712
375
3011
1.27
4.50
3.8
4.4
237.35
244.15
u/l
0.35
351
2864
3485
34163
1.37
4.50
22.0
19.1
40.43
40.74
%
0.76
3333
32224
338
2686
1.28
4.41
2.5
2.2
372.84
370.29
nmol/l
0.08
316
2460
3487
34197
1.37
4.38
21.9
19.1
254.36
254.41
e9/l
0.01
3426
33403
462
3813
1.24
4.38
2.4
2.4
136.44
131.48
ug/g
0.11
361
3075
213
1587
1.36
4.38
2.0
1.8
—
—
—
0
0
1342
12192
1.16
4.33
4.9
4.9
35.53
35.93
g/l
1.85
1268
11379
3487
34221
1.35
4.14
21.9
19.1
6.86
6.64
e9/l
4.03
3420
33332
253
1953
1.32
4.12
1.2
1.3
55.73
55.83
au/ml
0.00
12
117
3487
34224
1.35
4.11
21.9
19.1
4.52
4.53
e12/l
0.40
3414
33342
294
2317
1.29
4.11
2.5
2.7
10.41
10.57
g/l
0.24
270
2127
1438
13171
1.15
4.08
3.0
2.8
127.33
120.73
ug/l
0.26
1348
12299
3487
34231
1.35
4.04
22.0
19.2
136.09
136.40
g/l
0.65
3457
33791
1242
11284
1.15
3.91
1.9
1.9
95.52
96.05
pmol/l
0.14
645
5929
3114
30201
1.20
3.90
4.4
4.2
1.43
1.47
mmol/l
5.13
2894
28276
149
1069
1.41
3.88
5.7
5.6
1.70
1.66
%
0.15
140
1002
3131
30384
1.20
3.88
4.4
4.2
4.74
4.75
mmol/l
0.15
2936
28589
141
1004
1.42
3.83
1.7
1.7
—
—
—
0
0
3013
29150
1.18
3.81
4.0
3.8
1.38
1.31
mmol/l
4.53
2789
27110
68
414
1.65
3.80
1.4
1.3
6.98
7.22
mmol/l
0.29
61
366
508
4310
1.21
3.68
1.9
1.8
—
—
—
0
0
690
6024
1.18
3.63
1.5
1.4
2.23
2.39
g/l
1.93
417
3799
160
1178
1.37
3.60
3.1
2.7
0.63
0.65
%
0.37
160
1170
254
2001
1.29
3.59
2.0
1.9
—
—
—
0
0
295
2386
1.26
3.38
4.6
3.9
1.78
1.95
mmol/l
0.43
253
1999
161
1200
1.36
3.38
1.3
1.3
0.19
1.27
u/ml
—
8
108
3165
30822
1.19
3.35
4.8
4.6
2.85
2.83
mmol/l
0.34
2950
28820
202
1563
1.31
3.29
1.4
1.5
—
—
—
0
0
3021
29331
1.17
3.20
4.5
4.2
5.91
5.87
mmol/l
0.92
2797
27107
271
2198
1.25
3.06
1.2
1.2
144.18
154.05
iu/ml
0.14
86
861
78
1147
0.67
3.04
1.5
1.5
—
—
—
0
0
405
3429
1.20
3.02
2.2
2.8
7.46
7.96
umol/l
0.18
359
2983
497
4293
1.18
2.96
1.8
2.1
29.67
29.77
s
0.13
486
4157
88
605
1.47
2.96
2.5
2.2
134.12
130.54
g/l
0.74
66
434
592
5188
1.17
2.96
1.3
1.3
9.97
11.51
u/ml
0.24
234
2097
295
2425
1.24
2.95
6.9
8.1
9.08
9.33
mmol/l
0.29
283
2322
466
4013
1.18
2.88
2.8
2.5
2.37
2.34
g/l
0.57
429
3731
142
1068
1.34
2.86
5.9
5.7
0.89
0.90
%
0.16
134
1002
501
4344
1.18
2.86
2.8
2.5
13.59
13.70
umol/l
0.12
475
4065
83
569
1.47
2.85
1.9
1.7
—
—
—
0
0
227
1824
1.26
2.80
1.9
1.8
1.18
1.40
g/l
0.88
211
1674
261
2131
1.24
2.80
2.7
2.7
66.35
66.73
g/l
0.37
234
1971
44
262
1.69
2.76
1.8
1.5
33.40
32.38
%
0.07
28
156
702
6268
1.15
2.72
3.7
3.8
1.02
1.02
kg/l
0.03
124
912
1309
12162
1.12
2.68
2.4
2.2
76.43
76.58
nmol/l
0.07
1189
11119
602
5325
1.16
2.66
3.6
3.5
246.59
449.57
ng/l
1.49
421
3894
1104
10171
1.12
2.61
3.3
3.3
30.20
34.33
u/l
1.55
1058
9681
48
299
1.61
2.56
2.1
2.5
106.10
105.56
mmol/l
0.40
48
293
48
299
1.61
2.56
2.1
2.5
3.92
4.05
mmol/l
1.91
48
293
39
234
1.67
2.41
1.9
2.1
20.56
18.99
nmol/l
0.39
39
221
24
126
1.91
2.30
1.1
1.1
127.65
187.43
iu/ml
1.21
24
126
427
3729
1.16
2.26
2.9
2.6
23.17
23.68
%
0.31
376
3217
336
2880
1.18
2.23
2.2
2.6
1.81
1.78
%
0.15
295
2574
13
54
2.41
2.19
1.7
1.2
1.49
42.64
ug/l
—
5
23
37
227
1.64
2.14
2.1
2.0
—
—
—
0
0
516
4588
1.14
2.14
3.3
3.5
0.82
0.82
mmol/l
0.37
488
4327
38
235
1.62
2.13
2.2
2.0
11.29
15.14
%
2.23
38
230
251
2108
1.20
2.11
2.6
2.6
70.76
71.07
e9/l
0.04
196
1586
655
5924
1.13
2.09
1.7
1.6
79927413.44
36844625.77
pmol/l
0.60
548
5032
680
6166
1.13
2.07
1.6
1.5
20.61
20.56
nmol/l
0.03
567
5358
345
2985
1.17
2.07
1.8
1.7
—
—
—
0
0
407
3571
1.16
2.04
6.9
6.3
1.04
1.04
mmol/l
0.10
383
3337
114
882
1.30
1.98
1.4
1.3
—
—
—
0
0
47
312
1.51
1.98
2.1
2.3
31.33
20.04
mg/l
0.43
12
89
341
2960
1.17
1.97
1.8
1.7
—
—
—
0
0
868
8010
1.11
1.93
1.8
1.6
1.44
1.42
mmol/l
0.16
710
6790
119
930
1.29
1.93
2.1
2.3
323.27
476.90
ug/l
0.83
112
869
111
860
1.30
1.92
2.3
2.9
—
—
—
0
0
77
566
1.37
1.90
1.4
1.6
—
—
—
0
0
321
2787
1.17
1.86
3.6
4.1
7.42
24.11
ug/l
2.16
250
2227
9
34
2.65
1.86
1.0
1.0
—
—
—
0
0
231
1952
1.20
1.85
3.1
3.4
4.49
4.50
pmol/l
0.06
202
1744
320
2782
1.16
1.83
9.0
8.0
95.45
95.79
%
0.32
308
2693
59
419
1.41
1.79
1.1
1.1
4.33
3.96
u/ml
0.05
21
163
40
263
1.53
1.78
2.5
2.6
—
—
—
0
0
25
146
1.72
1.77
1.4
1.3
6.93
4.62
umol/l
0.32
25
139
764
7038
1.11
1.76
2.2
2.2
2.89
2.89
mg/l
0.01
653
6038
105
819
1.29
1.75
1.6
1.7
—
—
—
0
0
24
139
1.73
1.75
2.2
2.1
67.80
141.62
ug/min
—
5
34
6
18
3.34
1.74
1.0
1.1
7.16
8.14
mmol/l
—
6
18
12
54
2.23
1.73
2.2
1.3
—
—
—
0
0
928
8643
1.10
1.71
5.1
4.4
2.24
2.53
ug/l
0.36
828
7816
81
612
1.33
1.71
1.4
1.4
—
—
—
0
0
38
250
1.53
1.70
1.7
1.4
1.30
1.31
promille
0.01
29
197
945
8817
1.10
1.67
3.6
3.2
7.81
7.76
mmol/l
0.12
786
7546
154
1265
1.23
1.67
2.1
2.0
39.67
38.88
u/l
0.17
131
1153
50
350
1.43
1.66
1.4
1.6
67.07
59.47
%
0.71
28
215
189
1586
1.20
1.66
2.3
3.4
33.94
54.97
u/ml
1.37
179
1536
107
846
1.27
1.63
1.3
1.4
274.97
289.96
ug/g
0.31
59
486
82
626
1.32
1.62
4.4
5.7
1601.00
568.64
iu/ml
—
8
85
200
1692
1.19
1.61
1.4
1.3
23.96
30.31
iu/l
2.17
177
1444
1013
9498
1.09
1.61
2.9
3.4
2.35
2.35
mmol/l
0.79
889
8489
123
991
1.25
1.60
1.7
1.6
194.29
355.11
titre
—
7
45
16
84
1.91
1.59
1.6
1.4
59.06
162.61
nmol/24h
0.76
16
84
101
796
1.28
1.59
2.1
2.0
10.18
11.36
mg/l
0.79
94
745
258
2236
1.17
1.57
2.3
2.3
8.56
7.59
ug/l
0.20
228
1997
35
231
1.52
1.56
2.5
2.5
983.91
724.22
e6/l
0.37
35
223
109
869
1.26
1.56
1.1
1.1
3.02
4.26
u/ml
—
9
117
20
114
1.76
1.56
2.2
2.0
30.85
29.62
%
0.12
20
109
230
1979
1.17
1.54
1.4
1.3
411.07
215.93
u/ml
0.36
217
1826
147
1216
1.22
1.52
1.6
1.6
22.00
16.61
u/ml
—
6
36
0
44
0.00
1.51
0.0
2.1
—
—
—
0
0
25
154
1.63
1.49
1.9
1.6
—
—
—
0
0
25
154
1.63
1.49
1.9
1.6
—
—
—
0
0
564
5168
1.11
1.45
1.5
1.5
—
—
—
0
0
9
39
2.31
1.43
13.4
10.8
4.92
5.71
mmol/l
—
9
39
118
962
1.23
1.42
2.4
1.7
—
—
—
0
0
7
155
0.45
1.42
2.7
1.7
—
—
—
0
0
7
155
0.45
1.42
2.6
1.7
—
—
—
0
0
174
1475
1.19
1.41
12.0
10.6
—
—
—
0
0
520
4755
1.11
1.40
1.8
1.7
1184.49
1153.12
nmol/l
0.33
389
3671
347
3102
1.13
1.38
8.6
7.6
0.91
1.09
mmol/l
0.37
281
2459
348
3113
1.13
1.37
8.6
7.5
11.98
12.56
kpa
1.52
328
2980
16
89
1.80
1.37
1.0
1.0
—
—
—
0
0
15
82
1.83
1.35
1.3
1.2
—
—
—
0
0
27
175
1.55
1.34
1.0
1.1
0.87
1.13
u/l
—
9
91
294
2608
1.14
1.33
9.5
8.4
122.68
122.92
g/l
0.06
285
2542
347
3112
1.13
1.32
8.6
7.5
5.04
5.11
kpa
0.68
327
2980
78
617
1.27
1.25
8.6
7.8
105.70
105.28
mmol/l
0.36
70
555
861
8102
1.08
1.24
3.5
3.3
569.36
354.07
mg/l
0.55
545
5182
47
346
1.36
1.24
2.2
2.0
4.45
5.10
umol/l
0.35
35
247
70
549
1.28
1.20
3.7
3.6
132.53
783.51
u/ml
0.77
63
510
381
3458
1.11
1.20
4.3
4.2
31.76
31.83
%
0.04
284
2445
93
756
1.24
1.19
3.7
3.6
1.59
2.44
ratio
—
7
62
6
26
2.31
1.18
1.0
1.1
—
—
—
0
0
135
1142
1.19
1.16
2.1
1.6
293.41
295.68
mu/l
0.03
126
1042
35
486
0.72
1.16
1.6
1.6
—
—
—
0
0
35
486
0.72
1.16
1.6
1.6
—
—
—
0
0
41
299
1.38
1.16
1.9
2.0
15.71
23.66
ug/l
1.12
41
294
95
777
1.23
1.16
1.5
1.4
—
—
—
0
0
95
779
1.23
1.13
3.7
3.6
28.71
55.90
mg/l
1.59
74
634
95
779
1.23
1.13
3.7
3.6
33.94
63.27
mg/l
2.27
76
632
16
259
0.62
1.13
1.9
1.5
—
—
—
0
0
16
259
0.62
1.13
1.9
1.5
—
—
—
0
0
16
259
0.62
1.13
1.9
1.5
—
—
—
0
0
12
209
0.57
1.13
2.0
1.5
—
—
—
0
0
72
574
1.26
1.11
1.6
1.7
—
—
—
0
0
899
8514
1.07
1.10
4.1
3.9
12.73
8.25
mg/mmol
1.47
570
5448
28
193
1.45
1.09
2.7
2.7
39.36
43.47
%
0.60
23
105
66
523
1.27
1.07
1.9
1.9
5.50
5.17
mmol/24h
0.36
56
464
105
876
1.20
1.07
1.8
2.5
3.74
3.61
g/l
0.34
100
821
196
1723
1.15
1.06
7.7
7.1
24.76
24.54
mmol/l
0.37
186
1640
400
3667
1.10
1.06
2.2
2.0
—
—
—
0
0
17
105
1.62
1.06
2.1
1.9
—
—
—
0
0
61
480
1.28
1.05
3.5
2.7
2916.00
1655.29
u/ml
—
7
28
26
178
1.46
1.05
1.8
1.5
—
—
—
0
0
6
124
0.48
1.04
2.8
1.8
—
—
—
0
0
6
124
0.48
1.04
2.8
1.8
—
—
—
0
0
98
815
1.21
1.04
4.3
3.2
1.46
1.49
mg/l
0.20
93
763
6
125
0.48
1.04
3.0
1.8
—
—
—
0
0
59
464
1.28
1.03
1.1
1.1
4.67
2.79
u/ml
0.49
24
209
7
34
2.06
1.02
1.4
1.1
3.27
5.05
nmol/l
—
7
34
112
945
1.19
1.02
1.8
1.7
1.20
1.18
g/l
0.51
107
901
9
47
1.92
1.02
6.9
4.9
—
—
—
0
0
44
334
1.32
1.00
1.2
1.4
188.95
315.12
pmol/l
4.33
37
289
7
35
2.00
1.00
1.0
1.5
—
—
—
0
0
21
140
1.50
0.97
1.0
1.7
—
—
—
0
0
65
523
1.25
0.96
1.1
1.1
3.50
1.73
u/ml
0.58
25
249
62
497
1.25
0.94
1.1
1.1
4.10
10.13
au/ml
—
6
30
11
62
1.78
0.94
1.2
1.2
—
—
—
0
0
6
27
2.22
0.93
1.3
1.3
—
—
—
0
0
35
260
1.35
0.93
1.4
1.6
—
—
—
0
0
57
455
1.26
0.91
1.3
1.2
—
—
—
0
0
98
829
1.19
0.90
1.2
1.1
—
—
—
0
0
29
210
1.38
0.90
1.9
1.6
—
—
—
0
0
106
905
1.18
0.88
1.5
1.4
10.10
10.16
u/l
0.02
89
746
8
43
1.86
0.87
1.7
1.7
102.25
122.67
ng/l
—
8
43
537
5038
1.08
0.86
3.1
2.8
0.72
0.72
ug/l
0.03
349
3155
355
3275
1.09
0.86
2.1
1.9
—
—
—
0
0
8
44
1.82
0.85
1.0
1.1
31.81
49.37
mg/l
—
8
39
13
204
0.64
0.85
1.4
1.8
—
—
—
0
0
172
1528
1.13
0.84
1.7
1.6
—
—
—
0
0
23
162
1.42
0.84
1.6
3.1
—
—
—
0
0
48
382
1.26
0.81
1.0
1.1
0.19
0.30
u/ml
—
9
107
117
1016
1.16
0.80
1.7
1.8
—
—
—
0
0
37
286
1.30
0.78
2.5
5.7
5.98
7.37
mmol/l
4.35
26
241
27
199
1.36
0.78
1.1
1.6
—
—
—
0
0
20
140
1.43
0.76
1.4
1.4
—
—
—
0
0
33
252
1.31
0.76
1.2
1.2
35.63
42.93
mg/l
0.85
27
208
31
235
1.32
0.75
1.1
1.2
0.44
0.86
u/ml
0.65
15
122
23
166
1.39
0.75
1.7
1.5
11.09
13.36
u/l
1.35
23
160
9
53
1.70
0.75
3.1
2.2
1.21
1.20
mmol/l
—
9
53
17
116
1.47
0.74
2.4
4.3
—
—
—
0
0
27
357
0.75
0.73
1.1
1.2
—
—
—
0
0
5
25
2.00
0.72
1.0
1.1
—
—
—
0
0
68
572
1.19
0.71
1.0
1.1
4.61
4.93
u/ml
0.06
33
280
31
238
1.31
0.70
1.0
1.1
—
—
—
0
0
43
345
1.25
0.70
1.4
1.4
—
—
—
0
0
28
212
1.32
0.70
1.3
1.3
—
—
—
0
0
7
41
1.71
0.70
1.0
1.2
—
—
—
0
0
17
240
0.71
0.70
1.4
1.5
11.71
12.49
umol/l
0.15
17
227
7
42
1.67
0.68
1.0
1.2
—
—
—
0
0
20
144
1.39
0.67
1.4
1.3
—
—
—
0
0
7
44
1.59
0.65
1.0
1.2
—
—
—
0
0
38
304
1.25
0.65
1.0
1.1
—
—
—
0
0
52
431
1.21
0.64
1.6
1.4
—
—
—
0
0
16
112
1.43
0.63
2.1
2.0
9.66
9.29
mg/l
0.09
11
92
52
433
1.20
0.62
3.6
3.1
0.82
0.82
nmol/l
0.03
37
346
15
104
1.44
0.62
1.3
1.5
15.31
15.42
pmol/l
0.02
15
92
17
121
1.41
0.62
2.8
2.7
47.83
138.58
au/ml
—
6
19
38
306
1.24
0.62
1.2
1.2
—
—
—
0
0
129
1154
1.12
0.62
1.7
1.8
1.59
1.56
g/l
0.11
110
1001
20
268
0.74
0.62
1.2
1.4
195.27
198.08
pmol/l
0.02
20
268
98
862
1.14
0.61
2.8
2.5
0.48
1.06
g/l
1.62
83
764
71
610
1.17
0.61
1.2
2.0
0.94
0.84
nmol/l
0.69
66
511
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
70
602
1.17
0.59
2.9
3.4
20.63
24.86
mg/l
0.49
44
373
92
809
1.14
0.58
1.3
1.2
7.75
6.94
u/ml
—
6
82
19
140
1.36
0.58
1.1
1.1
—
—
—
0
0
19
140
1.36
0.58
1.7
2.0
146.13
169.08
umol/l
—
8
77
29
228
1.27
0.58
1.5
1.3
2.53
2.04
mmol/l
0.40
24
216
42
346
1.22
0.57
1.5
1.4
—
—
—
0
0
14
98
1.43
0.56
2.9
3.0
—
—
—
0
0
75
653
1.15
0.55
1.1
1.1
2.22
2.13
u/ml
0.03
34
318
6
37
1.62
0.55
1.0
1.0
—
—
—
0
0
10
65
1.54
0.55
3.1
2.2
16.60
16.91
umol/l
—
10
65
43
357
1.21
0.55
1.4
1.4
—
—
—
0
0
42
348
1.21
0.55
1.5
1.4
—
—
—
0
0
12
82
1.46
0.54
1.1
1.4
42.20
29.34
%
—
5
56
90
796
1.13
0.54
1.7
1.9
3.07
4.91
iu/l
2.29
33
299
216
2002
1.08
0.53
5.2
3.9
101.58
87.70
ng/l
0.99
195
1766
103
920
1.12
0.53
3.0
2.4
9.62
10.23
g/l
0.81
90
840
15
108
1.39
0.53
1.0
1.3
—
—
—
0
0
9
62
1.45
0.53
1.0
1.1
—
—
—
0
0
13
91
1.43
0.53
1.0
1.2
89.83
93.69
%
—
6
49
124
1122
1.11
0.51
1.9
1.9
—
—
—
0
0
45
379
1.19
0.51
1.6
1.4
—
—
—
0
0
13
92
1.41
0.50
1.0
1.1
85.33
89.35
%
—
6
49
86
763
1.13
0.50
2.9
2.3
0.00
0.02
g/l
1.50
77
715
6
41
1.46
0.50
1.2
1.1
—
—
—
0
0
6
41
1.46
0.50
1.0
1.0
—
—
—
0
0
13
179
0.73
0.50
1.0
1.2
—
—
—
0
0
58
501
1.16
0.49
1.5
1.5
—
—
—
0
0
26
207
1.26
0.49
1.4
1.2
—
—
—
0
0
27
216
1.25
0.49
1.0
1.0
—
—
—
0
0
109
983
1.11
0.49
2.8
3.6
244.19
1812.41
u/ml
0.87
98
845
34
280
1.22
0.48
1.2
1.4
—
—
—
0
0
63
549
1.15
0.48
1.0
1.1
0.71
1.04
u/ml
0.33
15
222
110
994
1.11
0.48
2.9
2.4
3.51
3.66
g/l
0.80
98
920
30
244
1.23
0.48
1.1
1.1
229.13
285.41
mg/l
2.00
24
210
50
428
1.17
0.48
1.1
1.1
—
—
—
0
0
110
995
1.11
0.47
2.9
2.4
—
—
—
0
0
110
995
1.11
0.47
2.9
2.4
7.28
7.34
g/l
0.13
98
918
42
355
1.19
0.47
1.5
1.4
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
96
864
1.11
0.46
3.5
3.3
0.39
0.35
u/ml
0.68
59
487
7
49
1.43
0.46
1.1
1.4
—
—
—
0
0
66
580
1.14
0.46
1.6
1.5
—
—
—
0
0
5
83
0.60
0.45
1.0
1.8
11.00
47.98
u/l
—
5
78
44
514
0.85
0.45
1.5
1.4
0.37
0.34
nmol/l
0.11
31
404
26
210
1.24
0.45
1.4
1.2
—
—
—
0
0
32
265
1.21
0.44
1.5
1.4
73460.67
84043.97
e6/l
0.06
21
180
7
51
1.37
0.44
2.1
1.6
—
—
—
0
0
7
51
1.37
0.44
1.3
1.5
—
—
—
0
0
127
1164
1.09
0.43
1.7
1.9
—
—
—
0
0
20
157
1.28
0.43
1.3
1.2
132.36
133.31
nmol/l
0.05
20
157
97
878
1.11
0.43
1.1
1.1
—
—
—
0
0
8
56
1.43
0.42
1.0
1.1
—
—
—
0
0
113
1236
0.91
0.42
1.7
1.7
2.92
4.50
mg/l
1.57
80
888
28
230
1.22
0.42
1.3
1.3
1.49
1.58
g/l
0.99
28
230
19
149
1.28
0.41
1.4
1.8
3.86
3.30
u/field
0.09
14
107
91
823
1.11
0.41
1.3
1.3
23.09
8.47
u/ml
—
10
130
0
15
0.00
0.41
0.0
13.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
8.85
—
0
16
0
16
0.00
0.41
0.0
1.1
—
36.13
—
0
16
0
16
0.00
0.41
0.0
1.1
—
22.34
—
0
16
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
0.34
—
0
13
239
2259
1.06
0.38
2.4
2.3
12.61
12.97
nmol/l
0.28
211
2053
15
115
1.31
0.38
1.3
1.2
—
—
—
0
0
58
654
0.89
0.38
1.2
1.2
—
—
—
0
0
19
151
1.26
0.38
2.1
1.3
29.15
31.04
nmol/l
0.06
19
128
69
618
1.12
0.38
3.1
3.0
31.17
36.93
umol/l
1.56
64
562
13
98
1.33
0.37
1.3
1.2
—
—
—
0
0
28
333
0.84
0.37
1.3
1.5
—
—
—
0
0
28
333
0.84
0.37
1.3
1.5
—
—
—
0
0
8
112
0.71
0.37
1.0
1.5
—
—
—
0
0
5
37
1.35
0.37
2.2
2.0
—
—
—
0
0
20
161
1.24
0.37
1.1
1.4
38.49
25.59
umol/l
0.85
20
152
24
199
1.21
0.35
1.8
1.4
290.00
356.77
u/l
0.50
24
192
56
499
1.12
0.34
1.4
1.4
28.04
26.94
u/l
0.10
49
421
102
940
1.09
0.34
3.0
2.4
2.86
2.95
g/l
0.60
90
865
76
691
1.10
0.33
1.7
1.7
8052.02
12934.17
e6/l
1.06
62
495
91
990
0.92
0.33
1.5
1.3
—
—
—
0
0
40
350
1.14
0.32
1.5
1.4
—
—
—
0
0
22
183
1.20
0.31
1.4
3.2
30.05
26.82
mu/l
0.14
22
177
14
110
1.27
0.31
1.4
1.4
—
—
—
0
0
14
110
1.27
0.31
1.4
1.4
—
—
—
0
0
24
202
1.19
0.31
1.1
1.1
1.08
1.05
ratio
—
8
73
7
97
0.72
0.30
1.1
1.6
8.65
8.55
ug/l
—
7
97
85
782
1.09
0.30
2.9
2.3
38.53
37.92
g/l
0.56
71
705
109
1015
1.08
0.30
1.3
1.3
166.20
219.75
miu/ml
1.07
53
491
20
166
1.21
0.29
2.3
1.8
—
—
—
0
0
26
222
1.17
0.29
2.8
2.3
659.15
613.81
ml
0.31
20
154
73
669
1.09
0.29
1.3
1.3
43.87
50.45
u/ml
—
9
71
16
130
1.23
0.28
1.0
1.4
147.81
162.95
mmol/24h
0.28
16
130
20
167
1.20
0.28
1.3
1.4
1.11
1.31
nmol/l
0.48
12
134
25
291
0.86
0.28
4.6
4.9
34.21
80.20
u/ml
—
7
91
10
76
1.32
0.28
1.0
1.1
—
—
—
0
0
10
76
1.32
0.28
1.0
1.1
—
—
—
0
0
93
865
1.08
0.27
1.7
2.4
185.08
187.02
%
0.07
88
821
63
688
0.91
0.27
1.8
1.6
—
—
—
0
0
72
663
1.09
0.26
2.8
2.3
139.91
115.46
ug/min
0.18
45
405
14
113
1.24
0.26
1.8
1.8
—
—
—
0
0
704
6887
1.03
0.26
4.3
3.9
21.92
21.41
%
0.32
336
3090
416
4041
1.03
0.25
1.8
1.8
1.57
1.45
%
1.42
360
3599
52
570
0.91
0.24
1.4
1.3
—
—
—
0
0
52
570
0.91
0.24
1.4
1.3
—
—
—
0
0
63
581
1.09
0.23
1.5
1.4
111.56
117.81
u/ml
0.24
26
113
182
1741
1.05
0.23
11.2
9.3
93.82
94.02
%
0.16
182
1735
128
1350
0.95
0.23
1.5
1.5
—
—
—
0
0
27
237
1.14
0.23
1.0
1.1
—
—
—
0
0
74
795
0.93
0.23
1.5
1.5
—
—
—
0
0
29
256
1.13
0.23
1.2
1.3
—
—
—
0
0
23
264
0.87
0.23
2.3
3.3
60.83
56.00
%
0.55
18
223
52
476
1.09
0.23
1.1
1.1
—
—
—
0
0
93
874
1.07
0.22
1.1
1.1
—
—
—
0
0
76
709
1.07
0.22
3.1
2.4
0.00
0.00
g/l
-0.00
69
663
27
238
1.14
0.22
1.0
1.1
—
—
—
0
0
40
362
1.11
0.22
1.1
1.1
—
—
—
0
0
5
41
1.22
0.22
1.0
1.0
—
—
—
0
0
5
42
1.19
0.21
1.2
1.4
2300007.28
858072.66
nmol/l
—
5
31
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
53
488
1.09
0.21
1.1
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
4.1
—
—
—
0
0
(46236287) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay
0
12
0.00
0.21
0.0
1.2
—
3425.71
—
0
7
46
502
0.92
0.21
1.9
1.7
—
—
—
0
0
5
43
1.16
0.21
1.2
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
27
240
1.13
0.20
1.0
1.1
—
—
—
0
0
27
240
1.13
0.20
1.0
1.1
—
—
—
0
0
29
260
1.12
0.19
3.2
4.1
—
—
—
0
0
27
241
1.12
0.19
1.0
1.1
—
—
—
0
0
246
2388
1.03
0.17
2.6
2.5
64.85
68.90
ml/min/173m2
0.76
97
907
24
214
1.12
0.17
1.6
2.2
1.67
1.67
u/field
0.00
12
93
69
732
0.94
0.17
1.4
1.4
—
—
—
0
0
42
388
1.08
0.16
1.7
1.6
—
—
—
0
0
334
3420
0.97
0.16
6.5
6.4
—
—
—
0
0
12
101
1.19
0.16
1.7
2.0
112.92
160.60
%
1.68
12
94
69
731
0.94
0.16
1.4
1.4
—
—
—
0
0
11
92
1.20
0.16
1.3
1.2
—
—
—
0
0
8
73
1.10
0.15
1.1
1.1
—
—
—
0
0
277
2701
1.03
0.15
2.5
2.3
0.22
0.22
g/l
0.76
265
2526
69
729
0.95
0.15
1.4
1.4
—
—
—
0
0
9
79
1.14
0.15
1.0
1.1
—
—
—
0
0
16
140
1.14
0.15
1.0
1.0
—
—
—
0
0
69
728
0.95
0.15
1.4
1.4
—
—
—
0
0
10
84
1.19
0.14
1.0
1.1
—
—
—
0
0
170
1650
1.03
0.13
1.3
1.4
—
—
—
0
0
70
666
1.05
0.13
1.4
1.2
3.62
3.72
mmol/l
0.44
62
625
26
284
0.91
0.13
1.8
1.4
1036.56
2358.24
e6/l
1.87
18
206
20
180
1.11
0.13
1.0
1.2
—
—
—
0
0
13
113
1.15
0.13
1.0
1.2
—
—
—
0
0
11
94
1.17
0.13
1.4
1.2
—
—
—
0
0
16
142
1.13
0.12
1.3
1.4
28.88
29.61
umol/l
0.14
16
135
495
5024
0.98
0.12
2.8
3.0
2.45
2.44
mmol/l
0.76
427
4408
14
123
1.14
0.12
2.5
2.4
—
—
—
0
0
10
85
1.18
0.12
1.0
1.1
—
—
—
0
0
25
229
1.09
0.12
1.2
1.1
—
60.57
—
0
7
317
3231
0.98
0.12
1.8
1.7
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
17
152
1.12
0.12
1.0
1.1
—
—
—
0
0
166
1615
1.03
0.12
1.1
1.0
—
—
—
0
0
117
1134
1.03
0.11
1.4
1.4
—
—
—
0
0
96
994
0.96
0.11
1.7
1.6
0.11
7.27
iu/ml
0.60
23
194
59
618
0.95
0.11
1.3
1.2
280.07
273.98
u/ml
0.07
35
380
32
299
1.07
0.10
1.0
1.1
—
—
—
0
0
22
202
1.09
0.10
1.2
1.2
—
—
—
0
0
13
146
0.89
0.10
1.0
1.1
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
—
—
—
0
0
5
45
1.11
0.09
2.6
1.5
—
—
—
0
0
48
503
0.95
0.09
1.1
1.1
—
—
—
0
0
65
675
0.96
0.09
1.8
1.6
—
—
—
0
0
32
339
0.94
0.08
1.1
1.1
—
—
—
0
0
32
339
0.94
0.08
2.4
2.3
—
—
—
0
0
5
62
0.81
0.08
1.0
1.2
—
—
—
0
0
17
185
0.92
0.08
1.5
1.5
—
—
—
0
0
5
64
0.78
0.08
1.0
1.2
—
—
—
0
0
31
328
0.94
0.08
1.5
1.6
—
—
—
0
0
69
667
1.04
0.08
1.4
1.4
11.91
32.12
e6/l
0.94
56
519
69
667
1.04
0.08
1.4
1.4
1018.35
1416.36
e6/l
0.26
57
545
48
460
1.04
0.08
1.0
1.1
4.95
3.21
u/ml
0.20
21
223
7
68
1.03
0.07
1.6
1.1
—
—
—
0
0
6
70
0.86
0.07
1.0
1.3
—
—
—
0
0
6
70
0.86
0.07
1.0
1.1
—
—
—
0
0
33
313
1.05
0.07
1.8
1.7
—
—
—
0
0
53
511
1.04
0.07
1.2
1.2
2.10
3.42
u/ml
0.79
20
166
21
223
0.94
0.06
1.6
1.7
—
—
—
0
0
14
129
1.09
0.05
2.4
3.3
—
—
—
0
0
42
405
1.04
0.05
1.3
1.3
—
—
—
0
0
38
366
1.04
0.05
1.2
1.4
3.67
3.73
ug/l
0.03
32
325
29
303
0.96
0.05
1.5
1.7
—
—
—
0
0
12
110
1.09
0.05
1.0
1.0
—
—
—
0
0
41
423
0.97
0.04
1.4
1.5
—
—
—
0
0
89
906
0.98
0.04
1.4
1.4
—
—
—
0
0
48
493
0.97
0.04
1.0
1.1
14025.50
20348.84
iu/ml
0.10
13
115
48
493
0.97
0.04
1.4
1.5
—
—
—
0
0
212
2100
1.01
0.04
2.4
2.8
191.21
178.53
ng/l
0.14
186
1901
66
647
1.02
0.03
1.6
1.5
—
—
—
0
0
51
498
1.02
0.03
1.2
1.2
2.50
5.00
u/ml
2.18
22
214
11
118
0.93
0.02
1.0
1.1
—
280.30
—
0
26
12
128
0.94
0.02
1.3
1.6
—
—
—
0
0
12
128
0.94
0.02
1.3
1.6
—
—
—
0
0
42
430
0.98
0.02
3.7
3.3
0.56
1.37
%
3.62
36
382
17
162
1.05
0.02
7.8
6.7
29.60
56.25
u/ml
—
5
44
32
312
1.03
0.02
1.4
1.1
—
—
—
0
0
55
542
1.01
0.01
1.5
1.7
—
—
—
0
0
24
247
0.97
0.01
1.9
1.4
38308.27
93615.48
e6/l
0.81
15
150
73
737
0.99
0.01
1.2
1.2
—
—
—
0
0
31
304
1.02
0.00
1.5
1.4
280.92
280.85
mosm/kgh2o
0.01
24
242
23
232
0.99
0.00
1.1
1.1
—
—
—
0
0
12
125
0.96
0.00
1.3
1.1
—
—
—
0
0
14
139
1.01
0.00
1.1
1.2
—
—
—
0
0
17
171
0.99
0.00
1.2
1.3
—
—
—
0
0
40
399
1.00
0.00
1.6
1.5
—
—
—
0
0
21
213
0.99
0.00
1.1
1.1
—
—
—
0
0
13
133
0.98
0.00
1.0
1.2
1997.77
1472.56
miu/ml
1.34
13
133
7
73
0.96
-0.00
1.0
1.1
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
8.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.5
—
0.37
—
0
6
8
79
1.01
-0.00
1.0
1.2
17.37
16.87
umol/l
—
8
73
23
230
1.00
-0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
8.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_APPENDOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_APPENDOTH | 1.152 [0.93, 1.43] | 0.2 |
| Birth year | 0.992 [0.98, 1.0] | 0.062 |
During the follow-up period (1.1.1998 — 31.12.2019), 155 out of 3277 females with K11_APPENDOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_APPENDOTH | 1.066 [0.88, 1.3] | 0.52 |
| Birth year | 0.991 [0.98, 1.0] | 0.089 |
During the follow-up period (1.1.1998 — 31.12.2019), 202 out of 3197 males with K11_APPENDOTH died.
Mortality risk
Mortality risk for people of age
years, who have K11_APPENDOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.088% | 0.285% |
| 5 | 0.562% | 1.552% |
| 10 | 1.442% | 3.661% |
| 15 | 2.692% | 6.828% |
| 20 | 4.667% | 11.537% |
Relationships between endpoints
↥Index endpoint: K11_APPENDOTH – Other appendicitis
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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