Drug-induced neutropenia

DRUGADVERS_NEUTROPENIA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D70.82#

1 out of 7 registries used, show all original rules.

2622

4. Check minimum number of events

None

2622

5. Include endpoints

None

2622

6. Filter based on genotype QC (FinnGen only)

2622

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12860 7872 4919
Only index persons 11777 7306 4471
Unadjusted period prevalence (%)
Whole population 0.19 0.23 0.14
Only index persons 0.23 0.27 0.17
Median age at first event (years)
Whole population 63.94 62.61 66.05
Only index persons 63.92 62.58 66.11

-FinnGen-

Key figures

All Female Male
Number of individuals 2622 1672 950
Unadjusted period prevalence (%) 0.52 0.57 0.42
Median age at first event (years) 62.66 60.48 66.49

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2393
Matched controls
23932
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
WW500
NOMESCO Finland
Blood transfusion
22.7
323.0
595
344
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
19.4
323.0
579
388
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
23.1
323.0
767
478
A49.9
ICD-10 Finland
Bacterial infection, unspecified
19.9
323.0
1205
1158
L03AA13
ATC
pegfilgrastim; parenteral
26.4
323.0
792
440
A04AA02
ATC
granisetron; systemic, transdermal
20.1
323.0
920
720
R50.9
ICD-10 Finland
Fever, unspecified
9.1
323.0
1016
1802
A03FA01
ATC
metoclopramide; systemic, rectal
16.0
323.0
1708
3231
JN4BD
NOMESCO Finland
Extensive body CT
8.8
323.0
903
1534
H02AB02
ATC
dexamethasone; systemic
24.1
323.0
1414
1350
115
Kela drug reimbursment
Breast cancer
9.5
323.0
772
1138
D70.82
ICD-10 Finland
Drug-induced neutropenia
+∞
323.0
2393
6
L03AA14
ATC
lipegfilgrastim; parenteral
30.6
320.3
436
173
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
15.9
309.3
530
420
L03AA02
ATC
filgrastim; parenteral
21.7
309.0
468
265
ZX120
NOMESCO Finland
Intravenous
7.9
277.5
717
1226
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
23.4
270.9
399
203
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
11.4
260.6
525
578
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.6
259.5
1395
5602
A04AA01
ATC
ondansetron; systemic, rectal
9.3
258.5
589
812
N02AA05
ATC
oxycodone; systemic
6.1
253.5
817
1865
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.1
226.5
1574
7637
XW000
NOMESCO Finland
Bone marrow biopsy
12.8
222.2
416
386
JN4AD
NOMESCO Finland
Body CT examination
7.5
222.1
581
976
XX3DW
NOMESCO Finland
Time consuming IT work
6.3
219.2
666
1374
J01MA12
ATC
levofloxacin; systemic
4.8
212.2
879
2582
A04AD12
ATC
aprepitant; systemic
16.7
203.5
337
232
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
28.3
202.9
281
112
A04AA55
ATC
palonosetron, combinations; systemic
13.2
196.6
361
317
Z51.5
ICD-10 Finland
Palliative care
9.2
195.1
439
571
HA1AA
NOMESCO Finland
X-ray mammography
6.5
191.2
555
1058
D70.89
ICD-10 Finland
Neutropenic splenomegaly
38.3
191.1
245
71
130
Kela drug reimbursment
Malignant tumour
6.8
185.2
520
944
L02BG04
ATC
letrozole; oral
7.2
181.9
485
817
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
10.4
181.2
376
420
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.9
179.4
496
878
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
10.1
177.6
375
432
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
20.4
173.5
266
146
WF049
NOMESCO Finland
Radiotherapy of metastasis
12.4
168.8
319
294
HAC20
NOMESCO Finland
Total mastectomy
8.8
167.2
383
506
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
28.1
166.1
230
90
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
10.7
157.9
322
344
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
20.5
155.9
238
128
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
6.5
152.2
434
788
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
6.9
152.2
414
705
TPX10
NOMESCO Finland
Implantation of vascular injection port
11.9
151.6
291
275
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
7.4
143.1
369
579
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.1
141.1
1160
5574
L02BA01
ATC
tamoxifen; oral
8.1
140.5
337
473
WZC30
NOMESCO Finland
Teaching
4.1
139.2
639
1943
A41.9
ICD-10 Finland
Sepsis, unspecified
10.5
135.3
277
295
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
34.2
133.2
175
55
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
8.5
131.9
305
402
PJA12
NOMESCO Finland
Sentinel node biopsy
4.9
128.5
473
1147
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
20.4
121.3
185
98
B01AB10
ATC
tinzaparin; parenteral
5.2
115.1
390
856
ZX112
NOMESCO Finland
Subcutaneous
11.7
114.8
221
207
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
6.1
113.4
334
619
L01BC06
ATC
capecitabine; oral
8.1
112.7
268
366
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.6
111.4
590
1978
M04AA01
ATC
allopurinol; systemic
4.0
110.3
502
1478
WF003
NOMESCO Finland
Adjuvant radiotherapy
7.7
108.9
267
382
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
9.9
107.5
226
250
D64.9
ICD-10 Finland
Anaemia, unspecified
4.5
107.5
423
1083
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.7
106.4
334
667
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
24.9
105.1
150
64
D69.5
ICD-10 Finland
Secondary thrombocytopenia
82.1
104.2
117
15
ZX070
NOMESCO Finland
Intensity modified radiotherapy
12.4
104.1
194
169
ZX080
NOMESCO Finland
Image guided radiotherapy
11.2
103.4
203
197
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
15.1
103.3
176
125
B01AB05
ATC
enoxaparin; parenteral
2.6
95.4
988
5100
A02BC02
ATC
pantoprazole; systemic
2.6
92.9
1774
12618
X76
ICPC
Malignant neoplasm breast female
10.7
92.4
185
186
JN6AD
NOMESCO Finland
CT of torso and neck
15.8
91.6
153
103
JN4CD
NOMESCO Finland
Very extensive body CT
6.5
91.1
252
425
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
89.5
710
3103
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
17.3
86.4
139
85
NK6AN
NOMESCO Finland
Total body bone isotope imaging
7.6
85.2
210
300
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
81.0
487
1752
C50.99
ICD-10 Finland
Breast, unspecified
7.1
78.8
203
309
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.8
78.5
281
641
TPH04
NOMESCO Finland
Cathetrisation of vein
2.7
77.9
670
3033
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.2
76.3
322
864
WW300
NOMESCO Finland
Transfer of autologic stem cells
50.3
76.2
92
19
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
11.2
75.6
147
139
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.7
73.5
179
250
H02AB06
ATC
prednisolone; systemic
2.2
71.6
1277
8239
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
11.4
71.6
138
128
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.9
70.3
318
905
C83.1
ICD-10 Finland
Mantle cell lymphoma
32.2
70.1
93
30
J01MA14
ATC
moxifloxacin; systemic
3.6
69.8
352
1097
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
8.1
69.4
163
215
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.2
68.9
227
471
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
8.6
68.8
155
191
L02BG06
ATC
exemestane; oral
10.7
68.4
136
134
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
16.3
68.2
112
72
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
6.8
67.7
178
278
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
12.5
66.5
122
102
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.6
66.3
250
598
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
10.4
65.4
132
134
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
10.4
63.6
128
129
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.4
63.4
659
3249
M05BX04
ATC
denosumab; parenteral
4.5
63.3
242
586
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
9.1
62.5
136
158
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
7.6
62.3
151
209
128
Kela drug reimbursment
Cancers of female genital organs
8.7
61.2
136
164
1CD02
NOMESCO Finland
NA
14.0
60.8
106
79
L01CB01
ATC
etoposide; systemic
28.2
59.9
82
30
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.6
59.3
181
342
TGC00
NOMESCO Finland
Bronchial lavation
6.7
59.1
157
248
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
9.3
58.9
126
142
L01CA04
ATC
vinorelbine; systemic
16.1
58.4
96
62
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.5
58.4
305
970
HAB40
NOMESCO Finland
Wedge excision of mammary gland
3.9
58.2
263
742
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
5.3
58.0
187
377
YNB10
NOMESCO Finland
Collection of stem cells for transplant
92.4
57.1
63
7
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
11.6
56.9
108
97
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
11.6
56.9
108
97
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
6.9
56.6
147
225
PJA10
NOMESCO Finland
Exploration of lymph nodes
11.0
56.5
110
104
WF004
NOMESCO Finland
Palliative radiotherapy
8.1
56.3
131
170
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
6.6
54.8
147
235
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
6.2
53.7
151
257
N02BE01
ATC
paracetamol; systemic, rectal
2.6
53.0
2136
18288
C03CA01
ATC
furosemide; systemic
2.1
51.3
702
3874
J01DB01
ATC
cefalexin; oral
2.2
50.0
2005
16732
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
19.6
49.9
76
40
TQW20
NOMESCO Finland
Tatoe
9.1
49.7
107
122
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
8.4
49.5
112
139
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
48.9
1287
9109
Z31.5
ICD-10 Finland
Genetic counselling
4.0
48.8
206
545
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.3
48.5
156
313
ZX108
NOMESCO Finland
Inhalation
17.8
48.2
76
44
C50
ICD-10 Finland
Malignant neoplasm of breast
6.0
47.2
135
235
ZX090
NOMESCO Finland
Other technic of radiotherapy
5.3
47.0
149
294
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.9
46.9
309
1151
HAE20
NOMESCO Finland
Reconstruction of areola and mamilla using graft or flap
8.1
46.7
108
139
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
8.4
46.5
105
130
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
45.4
980
6401
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.9
45.3
201
555
WF002
NOMESCO Finland
Radical radiotherapy
4.0
44.9
189
498
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
43.9
351
1467
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
43.8
743
4421
Z51.0
ICD-10 Finland
Radiotherapy session
8.9
43.8
95
110
J05AB11
ATC
valaciclovir; oral
2.5
43.8
395
1766
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
11.8
42.8
80
70
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
3.8
42.7
191
531
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.3
42.5
117
194
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.1
42.2
586
3207
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
7.5
42.1
102
141
N05AH02
ATC
clozapine; systemic
6.9
41.5
107
162
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
14.3
41.5
71
51
192
Kela drug reimbursment
Fulvestrant
15.9
41.5
68
44
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
40.7
256
920
WX402
NOMESCO Finland
General anaesthesia
2.2
40.6
476
2414
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
7.6
40.5
97
132
ZX121
NOMESCO Finland
Central venous catheter
26.0
40.3
56
22
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
6.5
40.1
107
170
AA1BD
NOMESCO Finland
Extensive CT of head and brain
5.2
40.1
130
263
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
33.2
39.8
52
16
N05CF01
ATC
zopiclone; oral
1.9
39.8
836
5336
A79
ICPC
Malignancy NOS
7.4
39.7
97
136
L02BA03
ATC
fulvestrant; parenteral
15.9
39.7
65
42
N05BA06
ATC
lorazepam; systemic, sublingual
3.6
39.5
187
545
Z80.3
ICD-10 Finland
Family history of malignant neoplasm of breast
6.9
39.4
101
152
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.3
39.1
207
658
N05AH03
ATC
olanzapine; systemic
3.4
39.0
205
648
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.0
38.9
130
272
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
12.2
38.7
71
60
B99
ICD-10 Finland
Other and unspecified infectious diseases
7.1
38.3
96
140
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.5
38.1
339
1496
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.4
38.1
198
621
HA1CG
NOMESCO Finland
Extensive MRI examination of mammary gland with high intensity magnet
6.5
37.5
100
159
FM1FN
NOMESCO Finland
Heart function isotope examination
16.0
37.4
61
39
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
5.1
37.2
122
250
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.6
37.1
288
1178
1501
Kela drug reimbursment
Palbociclib
14.3
37.0
63
45
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
5.9
36.9
106
186
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.8
36.4
254
975
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
4.9
36.2
123
262
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
21.6
36.2
53
25
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.6
35.9
286
1183
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
35.7
1021
7140
ED1AA
NOMESCO Finland
Mandipular X-ray examination
12.9
35.3
63
50
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.8
35.3
103
184
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
23.2
34.9
50
22
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
10.9
34.7
67
63
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
34.6
305
1337
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
11.1
34.5
66
61
A06AH03
ATC
naloxegol; oral
8.8
34.4
75
88
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
9.5
34.1
71
77
TGD00
NOMESCO Finland
Needle biopsy of lung
18.0
34.1
53
30
A41.8
ICD-10 Finland
Other specified sepsis
7.3
33.6
82
115
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
32.0
33.5
44
14
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
10.1
33.4
67
68
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
9.7
33.1
68
72
GD1AD
NOMESCO Finland
Thorax CT examination
3.5
33.0
162
485
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
9.8
32.9
67
70
B03XA02
ATC
darbepoetin alfa; parenteral
6.1
32.8
91
153
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
7.0
32.7
82
120
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
6.6
32.5
85
132
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
5.4
32.5
100
191
SPAT1255
SPAT
Intravenous administration of medicine
3.0
32.5
201
712
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
5.5
32.5
98
183
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
25.4
32.3
45
18
L02BG03
ATC
anastrozole; oral
5.7
32.3
95
172
A06AD11
ATC
lactulose; oral
2.2
32.1
356
1745
1XC02
NOMESCO Finland
NA
9.5
31.9
66
71
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
12.1
31.7
58
49
C82.1
ICD-10 Finland
Follicular lymphoma grade II
10.4
30.9
61
60
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
30.7
374
1906
R11
ICD-10 Finland
Nausea and vomiting
2.7
30.5
226
896
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.1
30.3
177
600
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
5.7
30.3
89
161
JN3AD
NOMESCO Finland
Abdominal CT examination
2.6
30.1
237
974
L01XE33
ATC
[U] palbociclib; oral
15.6
29.9
49
32
394
Kela drug reimbursment
Palbociclib
12.9
29.9
53
42
ZXD05
NOMESCO Finland
Urgent procedure
1.7
29.8
745
4928
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.8
29.8
132
364
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
14.6
29.7
50
35
ZXE00
NOMESCO Finland
One hour or less
1.7
29.5
961
6863
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
15.3
29.1
48
32
C50.82
ICD-10 Finland
Overall malignant tumor of the mammary gland, lobular tumor
10.6
28.7
56
54
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
5.2
28.6
90
177
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
7.3
28.4
69
97
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
21.9
28.3
41
19
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
3.6
28.1
132
382
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
8.0
27.9
64
82
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
6.9
27.7
70
104
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.5
27.4
229
969
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.0
27.2
166
581
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
27.1
710
4735
A46
ICD-10 Finland
Erysipelas
2.1
26.5
332
1708
TPX15
NOMESCO Finland
Removal of vascular injection port
15.6
26.4
43
28
9680/3-C77.8
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph nodes of multiple regions
23.5
26.1
37
16
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
5.1
25.9
84
171
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
7.7
25.6
60
80
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.8
25.5
111
302
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
25.3
363
1969
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
25.3
305
1540
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
8.9
25.3
54
62
9673/3-C42.1
ICD-O-3
Mantle cell lymphoma of bone marrow
36.0
25.2
32
9
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
20.9
25.2
37
18
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
11.4
25.1
47
42
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
25.1
997
7403
JAL30
NOMESCO Finland
Omentectomy
6.6
25.0
65
101
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
16.2
25.0
40
25
1XC03
NOMESCO Finland
NA
17.2
24.9
39
23
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
8.1
24.7
56
71
B00.2
ICD-10 Finland
Herpesviral gingivostomatitis and pharyngotonsillitis
15.6
24.6
40
26
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
24.5
382
2138
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
24.5
684
4617
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
4.8
24.1
81
172
127
Kela drug reimbursment
Transplant complication
5.5
23.9
72
135
WW409
NOMESCO Finland
Other aferesis
22.3
23.0
33
15
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
4.6
23.0
81
181
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
8.0
23.0
52
66
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.2
23.0
90
223
C56.71
ICD-10 Finland
Serous epithelial malignant tumor of the ovary
7.1
22.9
56
80
XX1XN
NOMESCO Finland
Other isotope examination
7.7
22.8
53
70
ZX131
NOMESCO Finland
Intrathecal
84.3
22.7
25
*
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
121.2
22.6
24
*
R50.8
ICD-10 Finland
Other specified fever
12.7
22.6
40
32
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.4
22.6
69
132
L02BB04
ATC
enzalutamide; oral
9.2
22.5
47
52
NK6AQ
NOMESCO Finland
Whole body bone SPET with low dose CT
15.0
22.5
37
25
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
6.8
22.4
57
86
ZZF00
NOMESCO Finland
Graft of adipose tissue
6.6
22.4
58
90
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.1
22.3
89
224
I97.2
ICD-10 Finland
Postmastectomy lymphoedema syndrome
10.2
22.3
44
44
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
6.7
22.3
57
87
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
3.2
22.2
119
382
Z2446
NOMESCO Finland
Social worker
2.5
22.1
179
744
PJW99
NOMESCO Finland
Other operation on lymphatic system
10.9
22.1
42
39
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
4.9
21.7
72
151
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
5.8
21.6
62
110
L02AE02
ATC
leuprorelin; implant, parenteral
3.2
21.6
117
379
ZX095
NOMESCO Finland
Combined chemoradiotherapy
7.9
21.5
49
63
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
4.3
21.4
80
190
HAE05
NOMESCO Finland
Reconstruction of breast using soft tissue and prosthesis
8.7
21.4
46
54
HAB99
NOMESCO Finland
Other partial excision of mammary gland
3.7
21.2
95
265
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.9
21.2
70
146
YJ1BD
NOMESCO Finland
Extensive CT examination of abdomen for dose design of radiotherapy
34.1
21.1
27
8
B02.9
ICD-10 Finland
Zoster without complication
2.6
21.1
162
653
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
24.4
20.8
29
12
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
14.2
20.8
35
25
3AA13
NOMESCO Finland
NA
19.6
20.8
31
16
F20.9
ICD-10 Finland
Schizophrenia, unspecified
4.0
20.7
83
211
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.5
20.6
166
687
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
3.4
20.5
101
305
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
20.5
320
1785
N05AD01
ATC
haloperidol; systemic
3.7
20.5
92
258
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.4
20.4
102
311
A07AA09
ATC
vancomycin; oral
6.2
20.3
55
91
KFC00
NOMESCO Finland
Unilateral orchiectomy
11.7
20.2
37
32
212
Kela drug reimbursment
Gout
4.8
20.1
68
146
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
7.3
20.0
48
67
C82.2
ICD-10 Finland
Follicular lymphoma grade III, unspecified
13.8
20.0
34
25
R18
ICD-10 Finland
Ascites
4.6
20.0
70
156
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
6.7
20.0
51
78
JAH00
NOMESCO Finland
Laparotomy
3.8
19.9
87
238
WB402
NOMESCO Finland
Demanding antibody therapy of primary tumour
10.1
19.8
39
39
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.3
19.6
200
931
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
5.6
19.5
57
104
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
9.7
19.3
39
41
J05AB01
ATC
aciclovir; systemic
1.7
19.3
500
3272
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
11.8
19.3
35
30
HAC15
NOMESCO Finland
Subcutaneous mastectomy with excision of mamilla
8.1
19.2
43
54
3018
Kela drug reimbursment
The combination of trifluridine and tipiracil
46.4
19.2
23
5
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
3.8
19.2
83
226
WX110
NOMESCO Finland
Local anesthesy
1.5
19.1
1573
13430
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
5.2
19.1
59
115
163
Kela drug reimbursment
Abiraterone and enzalutamide
6.8
19.1
48
72
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
5.3
19.1
58
111
ZZR10
NOMESCO Finland
Flap of skin and muscle
6.6
19.0
49
76
A07AA02
ATC
nystatin; oral
2.3
19.0
176
785
L01EF01
ATC
palbociclib; oral
14.9
18.9
31
21
C50.89
ICD-10 Finland
Overall malignant tumor of the mammary gland, other or undeterminated histology
7.3
18.8
45
63
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
28.0
18.7
25
9
ZZQ70
NOMESCO Finland
Free microvascular graft of lymph nodes
70.4
18.7
21
*
D70.80
ICD-10 Finland
Agranulocytic angina
191.4
18.6
19
*
1506
Kela drug reimbursment
The combination of trifluridine and tipiracil
38.7
18.6
23
6
WW402
NOMESCO Finland
Leucoferesis
38.7
18.6
23
6
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.8
18.5
123
457
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
5.1
18.5
58
115
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.3
18.4
175
790
3AA02
NOMESCO Finland
NA
44.3
18.2
22
5
R06AE07
ATC
cetirizine; oral
1.5
18.2
984
7661
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
9.9
18.1
36
37
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.0
18.1
236
1226
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.7
18.1
126
480
B72
ICPC
Hodgkin Lymphoma
33.2
18.0
23
7
L04AA06
ATC
mycophenolic acid; systemic
4.5
17.9
64
146
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
7.0
17.9
44
64
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
6.4
17.9
47
75
8500/3-C50.2
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-inner quadrant of breast
6.4
17.9
47
75
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
17.9
202
987
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.6
17.8
82
235
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
18.2
17.8
27
15
WW200
NOMESCO Finland
Immunization
3.4
17.6
87
264
JAH01
NOMESCO Finland
Laparoscopy
2.7
17.6
120
452
A28
ICPC
Limited function/disability NOS
1.8
17.6
309
1791
Z3231
NOMESCO Finland
Registered nurse
1.6
17.5
627
4443
XX1AD
NOMESCO Finland
Other CT-examination
8.4
17.5
38
46
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
12.1
17.3
31
26
TJA10
NOMESCO Finland
Laparocentesis
21.0
17.3
25
12
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
14.0
17.3
29
21
N02AA01
ATC
morphine; systemic, rectal
6.0
17.2
47
79
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
8.9
17.2
36
41
J01MA02
ATC
ciprofloxacin; systemic
1.5
17.0
862
6592
C83.00
ICD-10 Finland
Lymphocytic lymphoma
16.1
17.0
27
17
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
4.0
16.9
67
169
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.2
16.9
90
289
SPAT1109
SPAT
Analgesia with portable analgesic pump
9.6
16.9
34
36
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
4.5
16.8
59
133
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.4
16.7
141
598
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
9.8
16.6
33
34
N02AX02
ATC
tramadol; systemic, rectal
1.5
16.5
947
7415
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
3.8
16.5
71
193
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
10.1
16.4
32
32
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
6.1
16.4
44
73
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
5.9
16.3
45
77
HAE99
NOMESCO Finland
Other reconstruction of breast
5.8
16.3
46
81
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
10.5
16.2
31
30
H02AB09
ATC
hydrocortisone; systemic
3.6
16.1
72
202
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
16.8
16.1
25
15
PG1BD
NOMESCO Finland
Extensive CT angiography of tissue graft, e.g. assessment of TRAN graft
47.8
16.0
19
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
5.6
16.0
46
83
SPAT1254
SPAT
Administration of medicine
1.8
15.8
306
1827
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.8
15.8
101
366
N95.1
ICD-10 Finland
Menopausal and female climacteric states
0.4
15.8
51
1370
390
Kela drug reimbursment
Ibrutinib
33.6
15.7
20
6
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
15.8
15.7
25
16
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
8.8
15.7
33
38
N05BA04
ATC
oxazepam; oral
1.5
15.7
557
3922
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
9.3
15.7
32
35
R4110
NOMESCO Finland
Physiotherapy
1.5
15.7
608
4372
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.3
15.6
78
240
WE300
NOMESCO Finland
Profylactive therapy of malignancy with biomoidiers
85.6
15.6
17
*
JAL00
NOMESCO Finland
Biopsy of peritoneum
7.9
15.6
35
45
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.2
15.5
153
706
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
15.4
322
1968
188
Kela drug reimbursment
Psychosis requiring demanding treatment
5.1
15.3
48
96
A49.8
ICD-10 Finland
Other bacterial infections of unspecified site
10.5
15.2
29
28
L01BC59
ATC
trifluridine, combinations; systemic
28.8
15.2
20
7
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
20.2
15.1
22
11
5BA08
NOMESCO Finland
NA
7.8
15.1
34
44
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
6.4
15.0
39
62
TQB05
NOMESCO Finland
Puncture of skin of trunk
6.4
15.0
39
62
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.9
15.0
61
159
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
15.1
14.9
24
16
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.0
14.8
85
288
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
14.8
250
1427
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
3.4
14.7
72
218
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
18.5
14.7
22
12
L01BB05
ATC
fludarabine; systemic
25.2
14.7
20
8
C77.8
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of multiple regions
11.9
14.6
26
22
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.5
14.5
169
2924
L02BX03
ATC
abiraterone; oral
8.9
14.4
30
34
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
6.6
14.3
36
55
E0000UV
ATC
NA
1.4
14.2
850
6652
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
10.5
14.2
27
26
ZY010
NOMESCO Finland
Hospital outpatient
2.4
14.1
120
514
JFB00
NOMESCO Finland
Partial resection of small intestine
4.4
14.1
50
115
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
5.0
14.0
44
89
N04AA02
ATC
biperiden; systemic
3.5
13.9
64
185
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.5
13.8
111
460
B01AB04
ATC
dalteparin; parenteral
2.3
13.8
126
559
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
13.7
364
2377
ZZQ10
NOMESCO Finland
Free microvascular graft of skin and muscle
9.1
13.7
28
31
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.1
13.6
53
133
RS220
NOMESCO Finland
NA
4.5
13.6
47
105
A40.8
ICD-10 Finland
Other streptococcal sepsis
5.9
13.6
37
63
GEA00
NOMESCO Finland
Mediastinoscopy
12.1
13.6
24
20
N03AX16
ATC
pregabalin; oral
1.5
13.6
528
3781
X21
ICPC
Breast sympt/compl female other
3.5
13.5
62
179
WF099
NOMESCO Finland
Other radiotherapy
8.8
13.5
28
32
PJ1AN
NOMESCO Finland
Lymphsystem isotope imaging
16.3
13.4
21
13
A02BC01
ATC
omeprazole; systemic
1.5
13.3
595
4385
J94.8
ICD-10 Finland
Other specified pleural conditions
4.1
13.3
51
126
HA1TE
NOMESCO Finland
Supplementary or limited ultrasound examination of mammary glands
4.7
13.3
44
94
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
5.4
13.3
39
73
C90.0
ICD-10 Finland
Multiple myeloma
5.8
13.3
37
65
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
4.1
13.2
51
127
HA3AT
NOMESCO Finland
Pucture of mammary gland cyst with ultrasound examination
7.3
13.2
31
43
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
6.1
13.2
35
58
ZX100
NOMESCO Finland
Oral
4.1
13.2
50
123
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
6.9
13.1
32
47
L02AE03
ATC
goserelin; implant
4.6
13.1
45
100
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
6.5
13.1
33
51
8500/3-C50.3
ICD-O-3
Infiltrating duct carcinoma, NOS, of lower-inner quadrant of breast
11.0
13.0
24
22
HA6BA
NOMESCO Finland
Breast tomosynthesis specimen
4.4
13.0
46
106
L04AX01
ATC
azathioprine; systemic
2.4
12.9
108
457
UJF32
NOMESCO Finland
Coloscopy
1.5
12.9
575
4232
9680/3-C71.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of brain, NOS
50.3
12.8
15
*
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
5.5
12.8
37
68
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.6
12.8
93
367
WX702
NOMESCO Finland
Supraglottic ventilation device
2.2
12.8
134
635
QBB05
NOMESCO Finland
Revision of wound of skin of trunk
5.0
12.8
40
81
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
5.0
12.8
40
81
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.5
12.7
98
398
N05AH04
ATC
quetiapine; oral
1.6
12.7
335
2181
RD211
NOMESCO Finland
NA
2.3
12.7
113
495
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.0
12.7
158
806
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.3
12.5
61
186
SPAT1088
SPAT
Blood transfusion
8.7
12.5
26
30
C50.92
ICD-10 Finland
Malignant tumor in another specified localization in lobular gland, lobular tumor
8.7
12.5
26
30
R84
ICPC
Malignant neoplasm bronchus/lung
10.1
12.5
24
24
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
7.3
12.5
29
40
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
2.9
12.4
73
254
8461/3-C56.9
ICD-O-3
High grade serous carcinoma of ovary
7.6
12.4
28
37
TAB00
NOMESCO Finland
Lumbar puncture
2.4
12.4
106
458
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
4.3
12.3
45
107
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
8.0
12.3
27
34
8041/3-C34.9
ICD-O-3
Small cell carcinoma, NOS, of lung, NOS
11.7
12.3
22
19
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.1
12.3
66
216
ZX050
NOMESCO Finland
Stereotactic radiotherapy
6.4
12.1
31
49
1512
Kela drug reimbursment
Ibrutinib
26.8
12.0
16
6
S18
ICPC
Laceration/cut
1.4
12.0
918
7448
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
7.6
11.9
27
36
N06AX16
ATC
venlafaxine; oral
1.6
11.9
302
1947
KBV15
NOMESCO Finland
Cystoscopic change of ureteral stent
8.0
11.8
26
33
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
4.2
11.8
44
107
C34.86
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary microcellular carcinoma
14.7
11.8
19
13
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
11.7
752
5912
N63
ICD-10 Finland
Unspecified lump in breast
2.0
11.7
145
740
SPAT1153
SPAT
Removal of sutures
1.4
11.7
714
5565
HAD99
NOMESCO Finland
Other plastic operation on breast
6.3
11.7
30
48
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.4
11.7
98
419
YN1BD
NOMESCO Finland
Extensive CT examination of extremities for dose design of radiotherapy
16.5
11.7
18
11
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.2
11.6
60
191
L01XE27
ATC
[U] ibrutinib; oral
30.2
11.6
15
5
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
4.7
11.6
38
81
JN5AN
NOMESCO Finland
Total body isotope imaging
65.3
11.6
13
*
XX9CD
NOMESCO Finland
Very extensive complementary CT
19.0
11.6
17
9
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
7.2
11.5
27
38
C84.49
ICD-10 Finland
Peripheral T-cell lymphoma, unspecified cell type
+∞
11.5
11
*
L01AA02
ATC
chlorambucil; oral
13.7
11.4
19
14
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.5
11.4
88
360
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.3
11.4
55
167
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
4.6
11.4
38
83
C50.29
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland, other or undeterminated histology
6.4
11.4
29
46
C50.39
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, other or undeterminated histology
11.9
11.3
20
17
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
11.3
168
919
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
11.3
276
1759
9663/3-C77.9
ICD-O-3
Hodgkin lymphoma, nodular sclerosis, NOS, of lymph node, NOS
35.2
11.3
14
*
C81.2
ICD-10 Finland
Mixed cellularity classical Hodgkin lymphoma
35.2
11.3
14
*
JFF10
NOMESCO Finland
Loop enterostomy
7.3
11.2
26
36
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
5.9
11.2
30
51
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.3
11.1
100
442
C81.7
ICD-10 Finland
Other classical Hodgkin lymphoma
25.1
11.1
15
6
191
Kela drug reimbursment
Erlotinib
25.1
11.1
15
6
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.0
11.0
148
778
P01AB01
ATC
metronidazole; oral, rectal
1.4
11.0
874
7105
C50.50
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, no histological veryfication
10.1
11.0
21
21
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
10.1
11.0
21
21
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.1
11.0
121
585
XX2AT
NOMESCO Finland
Other injection with ultrasound examination
3.7
11.0
46
125
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
4.6
11.0
37
82
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.0
10.9
132
665
C50.00
ICD-10 Finland
Malignant tumor of nipple and areola, no histological veryfication
5.5
10.9
31
57
SPAT1263
SPAT
Sampling
1.4
10.9
907
7432
C56
ICD-10 Finland
Malignant neoplasm of ovary
8.3
10.8
23
28
WC125
NOMESCO Finland
Demanding cytostatic therapy of local tumor recidive
10.6
10.8
20
19
C50.80
ICD-10 Finland
Overall malignant tumor of the mammary gland, no histological veryfication
7.2
10.7
25
35
8461/3-C57.0
ICD-O-3
High grade serous carcinoma of fallopian tube
17.9
10.7
16
9
369
Kela drug reimbursment
Regorafenib
21.5
10.7
15
7
L04AD01
ATC
ciclosporin; systemic
3.1
10.7
57
187
N05AA01
ATC
chlorpromazine; systemic, rectal
3.8
10.7
44
118
JAL20
NOMESCO Finland
Excision or destruction of lesion of peritoneum
6.7
10.7
26
39
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
6.7
10.7
26
39
KH1FT
NOMESCO Finland
Exchange of urinary catheter with radiological guidance
7.6
10.7
24
32
C79.31
ICD-10 Finland
Secondary malignant tumor of the cerebellum
12.9
10.6
18
14
9680/3-C42.1
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of bone marrow
60.3
10.6
12
*
J01FF01
ATC
clindamycin; systemic
1.4
10.6
570
4327
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
5.1
10.6
32
63
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
2.8
10.6
67
245
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
2.4
10.5
88
376
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
3.4
10.5
49
145
A05AA02
ATC
ursodeoxycholic acid; oral
3.5
10.5
47
135
E83.4
ICD-10 Finland
Disorders of magnesium metabolism
14.3
10.5
17
12
J02AC03
ATC
voriconazole; systemic
14.3
10.5
17
12
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
1.9
10.5
145
770
D70
ICD-10 Finland
Agranulocytosis
110.5
10.4
11
*
C83.71
ICD-10 Finland
Burkitt's tumour
110.5
10.4
11
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
5.9
10.4
28
48
N05AA02
ATC
levomepromazine; systemic
2.2
10.4
100
458
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
16.1
10.3
16
10
WB303
NOMESCO Finland
Simple adjuvant therapy of malignancy with biomodifiers
12.1
10.3
18
15
C62.12
ICD-10 Finland
Malignant tumor of the descending testicle, embryonic carsinoma, teratocarcinoma or coriocarsinoma
32.7
10.3
13
*
C83.89
ICD-10 Finland
Other types of diffuse non-Hodgkin's lymphoma
32.7
10.3
13
*
ZYC01
NOMESCO Finland
Remote contact by phone
2.2
10.3
103
481
C50.9
ICD-10 Finland
Malignant neoplasm: Breast, unspecified
7.1
10.3
24
34
Z08.7
ICD-10 Finland
Follow-up examination after combined treatment for malignant neoplasm
5.5
10.3
29
53
XW4AT
NOMESCO Finland
Biopsy of other inner organ with ultrasound guidance
9.6
10.2
20
21
Z51.3
ICD-10 Finland
Blood transfusion (without reported diagnosis)
23.5
10.2
14
6
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.0
10.2
125
635
AA1AD
NOMESCO Finland
CT of head and brain
1.4
10.1
487
3614
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.5
10.1
78
319
HAE00
NOMESCO Finland
Reconstruction of breast using prosthesis
6.9
10.1
24
35
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
2.0
10.1
130
674
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
10.1
840
6862
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
6.5
10.0
25
39
8500/3-C50.1
ICD-O-3
Infiltrating duct carcinoma, NOS, of central portion of breast
6.5
10.0
25
39
G62.0
ICD-10 Finland
Drug-induced polyneuropathy
9.2
10.0
20
22
J70.2
ICD-10 Finland
Acute drug-induced interstitial lung disorders
14.6
10.0
16
11
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
10.0
164
926
JAH21
NOMESCO Finland
Staging laparoscopy
40.2
10.0
12
*
N05AN01
ATC
lithium; oral
2.8
9.9
62
224
F20.10
ICD-10 Finland
Raise schizophrenia continuously
7.6
9.9
22
29
A02BC05
ATC
esomeprazole; systemic
1.3
9.9
877
7225
AAG00
NOMESCO Finland
Stereotactic intracranial biopsy
12.2
9.8
17
14
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
12.2
9.8
17
14
HWD00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of mammary gland
5.4
9.8
28
52
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
2.8
9.8
62
227
HA1BA
NOMESCO Finland
Extensive X-ray mammography
5.7
9.8
27
48
C50.20
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,no histological veryfication
5.7
9.8
27
48
C78.1
ICD-10 Finland
Secondary malignant neoplasm of mediastinum
20.1
9.8
14
7
T80.8
ICD-10 Finland
Other complications following infusion, transfusion and therapeutic injection
20.1
9.8
14
7
C50.52
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, lobular tumor
7.0
9.8
23
33
1CD01
NOMESCO Finland
NA
10.7
9.8
18
17
I89.0
ICD-10 Finland
Lymphoedema, not elsewhere classified
4.8
9.8
31
65
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
9.7
171
987
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
3.7
9.7
41
113
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
7.4
9.7
22
30
N05AX12
ATC
aripiprazole; systemic
2.3
9.7
85
373
9680/3-C16.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of stomach, NOS
55.2
9.6
11
*
D61.1
ICD-10 Finland
Drug-induced aplastic anaemia
55.2
9.6
11
*
QB2S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in chest
5.6
9.6
27
49
B34.9
ICD-10 Finland
Viral infection, unspecified
2.8
9.6
60
216
N05AF05
ATC
zuclopenthixol; systemic
3.9
9.6
38
99
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.7
9.6
64
241
A03
ICPC
Fever
1.5
9.5
298
2020
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
10.1
9.5
18
18
XX9BW
NOMESCO Finland
Submitting image material and/or investigation material to authority or other institution
3.8
9.5
39
105
J02AC01
ATC
fluconazole; systemic
1.3
9.5
872
7210
C50.10
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, no histological veryfication
6.6
9.4
23
35
9698/3-C77.8
ICD-O-3
Follicular lymphoma, grade 3 of lymph nodes of multiple regions
100.4
9.4
10
*
B00.19
ICD-10 Finland
Other vesicular dermatitis caused by the herper simplex virus
6.2
9.4
24
39
352
Kela drug reimbursment
Abiraterone and enzalutamide
5.3
9.4
27
51
WC115
NOMESCO Finland
Cytostatic therapy of local tumor recidive with multiple drugs
21.8
9.3
13
6
1AA09
NOMESCO Finland
NA
21.8
9.3
13
6
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
2.6
9.3
67
265
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
9.5
9.3
18
19
HA2AT
NOMESCO Finland
Cytology of mammary gland with ultrasound guidance
6.0
9.2
24
40
C20
ICD-10 Finland
Malignant neoplasm of rectum
6.0
9.2
24
40
I88.9
ICD-10 Finland
Nonspecific lymphadenitis, unspecified
7.3
9.2
21
29
F29
ICD-10 Finland
Unspecified nonorganic psychosis
2.3
9.2
79
344
R4190
NOMESCO Finland
Nutritional therapy
2.4
9.1
75
318
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
2.4
9.1
78
338
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
8.3
9.1
19
23
J01CA04
ATC
amoxicillin; systemic
1.3
9.1
1773
16285
C34.96
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary microcellular carcinoma
36.8
9.0
11
*
C57.0
ICD-10 Finland
Malignant neoplasm: Fallopian tube
10.1
9.0
17
17
A04AA03
ATC
tropisetron; systemic
10.1
9.0
17
17
P72
ICPC
Schizophrenia
3.1
9.0
46
148
ZXA05
NOMESCO Finland
Left side
1.4
9.0
526
4043
TQW99
NOMESCO Finland
Other minor procedure on skin
2.0
9.0
107
540
WNF00
NOMESCO Finland
Infection source and contact determination
6.1
8.9
23
38
WD215
NOMESCO Finland
Multiple therapy of methastized malignancy with hormones
24.1
8.9
12
5
E83.50
ICD-10 Finland
Hypercalcemia
3.7
8.8
37
102
C77.2
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intra-abdominal lymph nodes
5.9
8.7
23
39
L02AB02
ATC
medroxyprogesterone; systemic (progestogens)
5.6
8.7
24
43
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
3.9
8.7
34
88
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
3.1
8.7
45
146
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
4.2
8.7
31
74
LAF16
NOMESCO Finland
Excision of uterus, adnexes and lymph nodes for treatment of ovarian cancer
4.9
8.7
27
56
C50.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of breast
7.7
8.6
19
25
HA1BG
NOMESCO Finland
MRI examination of mammary gland with high intensity magnet
4.6
8.6
28
61
HAD40
NOMESCO Finland
Mastopexy
5.8
8.6
23
40
V03AF03
ATC
calcium folinate; systemic
16.3
8.5
13
8
N05AL05
ATC
amisulpride; oral
16.3
8.5
13
8
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
6.9
8.5
20
29
C50.59
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, other or undeterminated histology
6.9
8.5
20
29
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
6.9
8.5
20
29
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.9
8.5
120
644
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
8.5
780
6419
372
Kela drug reimbursment
Idelalisib
90.4
8.4
9
*
NF3AA
NOMESCO Finland
Femur X-ray examination
2.9
8.4
48
165
SPAT1290
SPAT
Preparation of deceased person
12.8
8.4
14
11
L01AA01
ATC
cyclophosphamide; systemic
7.9
8.4
18
23
SPAT1269
SPAT
Other puncture and/or drainage
4.5
8.3
28
63
N06DX01
ATC
memantine; oral
0.2
8.3
9
419
K59.09
ICD-10 Finland
Constipation, unspecified
1.9
8.3
119
644
HAD60
NOMESCO Finland
Replacement of prosthetic implant in breast
8.6
8.3
17
20
D75
ICPC
Malignant neoplasm colon/rectum
5.3
8.3
24
46
YN7AD
NOMESCO Finland
CT examination of spine for dose design of radiotherapy
10.8
8.3
15
14
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
4.0
8.2
31
78
N05AX08
ATC
risperidone; systemic
1.8
8.2
142
818
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
4.5
8.2
27
60
ECB20
NOMESCO Finland
Oral alveoplasty
4.1
8.2
30
74
GD6AD
NOMESCO Finland
CT of chest and neck
7.5
8.2
18
24
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
7.5
8.2
18
24
C50.19
ICD-10 Finland
Malignant tumor of the central part of the mammary gland, other or undeterminated histology
6.0
8.1
21
35
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
6.0
8.1
21
35
C50.22
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,lobular tumor
5.4
8.1
23
43
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.7
8.1
33
89
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.7
8.1
33
89
JN5JR
NOMESCO Finland
Extensive PET-CT of upper body metabolism (eyebrows to thighs)
33.5
8.1
10
*
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.7
8.1
53
201
C34.36
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung microcellular carcinoma
11.7
8.1
14
12
ZX114
NOMESCO Finland
Intramuscular
3.1
8.1
41
132
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
2.5
8.1
62
254
X77
ICPC
Malignant neopl genital female other
6.8
8.1
19
28
L01XE03
ATC
[U] erlotinib; oral
22.1
8.0
11
5
D70.81
ICD-10 Finland
Neutropenia congenital
22.1
8.0
11
5
N06AX11
ATC
mirtazapine; oral
1.3
8.0
646
5213
HA1HA
NOMESCO Finland
Tomosynthesis mammography
5.3
8.0
23
44
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
5.9
8.0
21
36
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
5.5
8.0
22
40
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.0
8.0
97
493
C78.8
ICD-10 Finland
Secondary malignant neoplasm of other and unspecified digestive organs
7.2
8.0
18
25
C77.3
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Axillary and upper limb lymph nodes
7.2
8.0
18
25
B37.08
ICD-10 Finland
Other candidal stomatitis
4.4
7.9
27
62
QBJ00
NOMESCO Finland
Liposuction in trunk
5.1
7.8
23
45
SPAT1229
SPAT
Assessment of need for aid
1.7
7.8
164
1001
116
Kela drug reimbursment
Prostate cancer
2.0
7.8
92
463
ZXA00
NOMESCO Finland
Right side
1.3
7.8
551
4352
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
3.1
7.8
40
130
X19
ICPC
Breast lump/mass female
3.1
7.8
40
130
R60.0
ICD-10 Finland
Localized oedema
1.6
7.8
217
1428
Z94.2
ICD-10 Finland
Lung transplant status
10.8
7.8
14
13
WB111
NOMESCO Finland
Multiple neoadjuvant cytostatic therapy
10.8
7.8
14
13
-50
ICPC
Medication/prescr/renewal
2.1
7.8
89
442
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.6
7.8
54
211
8500/3-C50.5
ICD-O-3
Infiltrating duct carcinoma, NOS, of lower-outer quadrant of breast
4.8
7.8
24
50
9680/3-C80.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of unknown primary site
45.1
7.7
9
*
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
15.1
7.7
12
8
K12.10
ICD-10 Finland
Stomatitis NOS
5.3
7.7
22
42
PJD63
NOMESCO Finland
Laparoscopic dissection of aortic lymph nodes
5.3
7.7
22
42
SPAT1301
SPAT
No procedures
1.3
7.7
650
5274
N03AG01
ATC
valproic acid; systemic, rectal
1.8
7.6
124
700
C56.00
ICD-10 Finland
Malignant tumor of the ovary without histology
4.7
7.6
24
51
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
2.5
7.6
57
233
AAA10
NOMESCO Finland
Biopsy through craniotomy
18.4
7.6
11
6
1XC07
NOMESCO Finland
NA
8.0
7.6
16
20
C54.21
ICD-10 Finland
Leiomyosarcoma and myometrium
11.9
7.6
13
11
C84.51
ICD-10 Finland
Other and unspecified T-cell lymphomas
25.1
7.6
10
*
K50.1
ICD-10 Finland
Crohn disease of large intestine
3.6
7.6
32
90
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
3.9
7.5
29
75
2951C
ICD-9 Finland
Schizophrenic psychoses, Disorganised type[HEBEFREENISTYYPPINEN SKITSOFRENIA,KROONINEN]
8.9
7.5
15
17
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
3.5
7.5
32
91
A98
ICPC
Health maint/preventive medicine
0.7
7.5
2111
21937
A07EA06
ATC
budesonide; oral, local oral
2.2
7.4
70
320
C62.10
ICD-10 Finland
Malignant tumor of the descending testicle, no histological verification
80.3
7.4
8
*
9652/3-C77.9
ICD-O-3
Hodgkin lymphoma, mixed cellularity, NOS, of lymph node, NOS
80.3
7.4
8
*
E87.6
ICD-10 Finland
Hypokalaemia
2.3
7.4
67
301
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.6
7.4
171
1073
C81.0
ICD-10 Finland
Nodular lymphocyte predominant Hodgkin lymphoma
13.4
7.4
12
9
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
13.4
7.4
12
9
L01BC53
ATC
tegafur, combinations; systemic
13.4
7.4
12
9
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
3.1
7.4
37
119
K56.7
ICD-10 Finland
Ileus, unspecified
3.1
7.4
37
119
N17.8
ICD-10 Finland
Other acute renal failure
3.7
7.3
30
82
L02BB03
ATC
bicalutamide; oral
2.6
7.3
49
189
R06.0
ICD-10 Finland
Dyspnoea
1.3
7.3
493
3863
1BC01
NOMESCO Finland
NA
+∞
7.3
7
*
WPB10
NOMESCO Finland
Making a convalescent care decision
+∞
7.3
7
*
L01XX47
ATC
[U] idelalisib; oral
+∞
7.3
7
*
F20.1
ICD-10 Finland
Hebephrenic schizophrenia
10.9
7.3
13
12
Z43.3
ICD-10 Finland
Attention to colostomy
9.4
7.3
14
15
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.2
7.3
72
339
ZXC40
NOMESCO Finland
Use of ultrasound
4.5
7.3
24
54
NE1DG
NOMESCO Finland
Pelvic, hip and femur very extensive MRI examination with high intensity magnet
5.2
7.2
21
41
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
5.2
7.2
21
41
WB223
NOMESCO Finland
Demanding adjuvant hormone therapy of malignancy
6.2
7.2
18
29
Z80.4
ICD-10 Finland
Family history of malignant neoplasm of genital organs
6.2
7.2
18
29
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.6
7.2
196
1284
JJ6LT
NOMESCO Finland
Coagulation of focal hepatic lesion under ultrasound guidance
15.8
7.2
11
7
HAC25
NOMESCO Finland
Radical mastectomy
7.3
7.2
16
22
Z85.7
ICD-10 Finland
Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
30.1
7.1
9
*
C83.33
ICD-10 Finland
Primary medical lymphoma with large B cells
30.1
7.1
9
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
30.1
7.1
9
*
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
2.9
7.1
41
142
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
20.1
7.1
10
5
C84.59
ICD-10 Finland
Other and unspecified T-cell lymphomas
20.1
7.1
10
5
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
7.1
761
6365
Y83.4
ICD-10 Finland
Other reconstructive surgery as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
12.1
7.1
12
10
1CX01
NOMESCO Finland
NA
12.1
7.1
12
10
A07EC01
ATC
sulfasalazine; oral, rectal
1.6
7.0
166
1049
159
Kela drug reimbursment
Pazopanib
10.0
7.0
13
13
C50.2
ICD-10 Finland
Malignant neoplasm: Upper-inner quadrant of breast
10.0
7.0
13
13
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
3.4
7.0
31
91
XF600
NOMESCO Finland
Bloodpressure measurement
1.8
7.0
122
706
SPAT1262
SPAT
Handing over of treatment supplies
1.4
7.0
361
2705
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
4.9
7.0
21
43
TK800
NOMESCO Finland
Hemodialysis
2.6
7.0
49
194
X26
ICPC
Fear of breast cancer female
4.5
6.9
23
52
QBA00
NOMESCO Finland
Puncture of skin of trunk
5.2
6.9
20
39
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.9
6.9
97
521
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.5
6.9
232
1596
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
6.9
339
2516
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
13.8
6.9
11
8
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
6.9
425
3281
RF210
NOMESCO Finland
NA
2.3
6.9
61
273
UDC00
NOMESCO Finland
Ear microscopy
1.7
6.8
140
853
Z73.8
ICD-10 Finland
Other problems related to life-management difficulty
4.8
6.8
21
44
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
2.7
6.8
42
155
C57.9
ICD-10 Finland
Malignant neoplasm: Female genital organ, unspecified
8.3
6.8
14
17
6BA02
NOMESCO Finland
NA
8.3
6.8
14
17
WX720
NOMESCO Finland
Own respiration
2.1
6.8
75
368
ZSH00
NOMESCO Finland
Procedure related to previous procedure classified in chapter H
4.5
6.8
22
49
J70.4
ICD-10 Finland
Drug-induced interstitial lung disorders, unspecified
40.2
6.8
8
*
9680/3-C09.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of tonsil, NOS
40.2
6.8
8
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.7
346
2589
1XX32
NOMESCO Finland
NA
16.7
6.7
10
6
K50.9
ICD-10 Finland
Crohn disease, unspecified
3.0
6.7
35
116
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
2.8
6.7
40
144
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.2
6.7
9
369
R53
ICD-10 Finland
Malaise and fatigue
1.4
6.7
376
2857
9085/3-C62.9
ICD-O-3
Mixed germ cell tumor of testis, NOS
22.6
6.7
9
*
1DB03
NOMESCO Finland
NA
22.6
6.7
9
*
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
4.4
6.6
22
50
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
2.7
6.6
43
162
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
4.2
6.6
23
55
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.4
6.6
51
214
B73
ICPC
Leukaemia
12.3
6.6
11
9
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
12.3
6.6
11
9
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
8.7
6.5
13
15
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
3.3
6.5
30
91
KA1FN
NOMESCO Finland
Isotope renography
4.3
6.5
22
51
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
4.8
6.5
20
42
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
2.6
6.5
44
172
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
4.1
6.5
23
56
TGA30
NOMESCO Finland
Thoracocentesis
4.1
6.5
23
56
QB9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in torso, unspecified
5.0
6.5
19
38
KBV00
NOMESCO Finland
Insertion of stent into ureter
5.0
6.5
19
38
8520/3-C50.4
ICD-O-3
Lobular carcinoma, NOS, of upper-outer quadrant of breast
4.0
6.5
24
61
LCA06
NOMESCO Finland
Biopsy of endometrium
1.5
6.5
245
1731
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
3.7
6.5
26
71
HWH99
NOMESCO Finland
Other reoperation in surgery of mammary gland
6.2
6.5
16
26
1BC07
NOMESCO Finland
NA
70.0
6.4
7
*
JL1AT
NOMESCO Finland
Biopsy of pancreas with ultrasound guidance
14.3
6.4
10
7
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
2.1
6.4
65
309
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
4.1
6.4
23
57
TDM10
NOMESCO Finland
Puncture of maxillary antrum
1.9
6.4
81
423
K92.1
ICD-10 Finland
Melaena
1.9
6.4
89
481
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.0
6.3
74
373
F20.3
ICD-10 Finland
Undifferentiated schizophrenia
5.2
6.3
18
35
RS140
NOMESCO Finland
NA
9.3
6.3
12
13
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
3.6
6.3
26
73
8140/3-C34.1
ICD-O-3
Adenocarcinoma, NOS, of upper lobe, lung
4.6
6.3
20
44
C80.99
ICD-10 Finland
Malignant tumor without specified localization or histology
18.1
6.3
9
5
9673/3-C77.9
ICD-O-3
Mantle cell lymphoma of lymph node, NOS
18.1
6.3
9
5
178
Kela drug reimbursment
Combination product containing tegafur, gimeracil and oteracil
18.1
6.3
9
5
C79.2
ICD-10 Finland
Secondary malignant neoplasm of skin
18.1
6.3
9
5
C56.73
ICD-10 Finland
Endomeroid epithelial carcinoma of the ovary
6.3
6.2
15
24
8070/3-C34.3
ICD-O-3
Squamous cell carcinoma, NOS, of lower lobe, lung
6.3
6.2
15
24
Z51.88
ICD-10 Finland
Other specified medical care
2.6
6.2
41
159
K83.1
ICD-10 Finland
Obstruction of bile duct
3.0
6.1
32
107
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
3.0
6.1
32
107
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
3.2
6.1
30
96
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
3.4
6.1
27
80
WX400
NOMESCO Finland
Inhalation anesthesy
1.9
6.1
85
460
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
3.5
6.1
26
75
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
4.0
6.1
22
55
C88.0
ICD-10 Finland
Waldenström macroglobulinaemia
12.5
6.1
10
8
GDG10
NOMESCO Finland
Bilateral transplantation of lung
12.5
6.1
10
8
C85.7
ICD-10 Finland
Other specified types of non-Hodgkin lymphoma
12.5
6.1
10
8
Z42.1
ICD-10 Finland
Follow-up care involving plastic surgery of breast
3.9
6.1
23
60
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
2.9
6.1
35
123
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
3.3
6.1
28
86
C34.92
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary adenocarcinoma
8.6
6.1
12
14
D76
ICPC
Malignant neoplasm pancreas
8.6
6.1
12
14
F20.5
ICD-10 Finland
Residual schizophrenia
4.4
6.0
20
46
L01XE11
ATC
[U] pazopanib; oral
10.0
6.0
11
11
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
10.0
6.0
11
11
176
Kela drug reimbursment
Regorafenib
10.0
6.0
11
11
ZYY98
NOMESCO Finland
Missed treatment contact, no notification given by patient
10.0
6.0
11
11
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
2.5
6.0
44
180

Mortality – FinRegistry

Association

Association between endpoint DRUGADVERS_NEUTROPENIA and mortality.

Females

Parameter HR [95% CI] p-value
DRUGADVERS_NEUTROPENIA 8.726 [7.5, 10.15] < 0.001
Birth year 0.992 [0.98, 1.0] 0.057

During the follow-up period (1.1.1998 — 31.12.2019), 2730 out of 6944 females with DRUGADVERS_NEUTROPENIA died.

Males

Parameter HR [95% CI] p-value
DRUGADVERS_NEUTROPENIA 9.331 [7.49, 11.63] < 0.001
Birth year 0.988 [0.98, 1.0] 0.013

During the follow-up period (1.1.1998 — 31.12.2019), 2303 out of 4090 males with DRUGADVERS_NEUTROPENIA died.

Mortality risk

Mortality risk for people of age

years, who have DRUGADVERS_NEUTROPENIA.

N-year risk Females Males
1 0.721% 1.851%
5 4.66% 10.622%
10 11.24% 23.446%
15 20.101% 40.366%
20 32.103% 60.541%

Relationships between endpoints

Index endpoint: DRUGADVERS_NEUTROPENIA – Drug-induced neutropenia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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