Other disorders of optic [2nd] nerve and visual pathways

H7_OPTNEUROTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H47
  • Cause of death: ICD-10 H47

2 out of 7 registries used, show all original rules.

2296

4. Check minimum number of events

None

2296

5. Include endpoints

2411

6. Filter based on genotype QC (FinnGen only)

2411

Control definitions (FinnGen only)

Control exclude
H7_OPTNERVE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H46-H48
Name in latin
Aliae morbositates nervi optici et tractuum opticorum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 18167 9612 8441
Only index persons 15970 8659 7311
Unadjusted period prevalence (%)
Whole population 0.26 0.28 0.24
Only index persons 0.30 0.32 0.28
Median age at first event (years)
Whole population 49.41 48.19 50.72
Only index persons 48.82 47.35 50.55

-FinnGen-

Key figures

All Female Male
Number of individuals 2411 1396 1015
Unadjusted period prevalence (%) 0.46 0.48 0.45
Median age at first event (years) 53.04 48.88 58.74

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2123
Matched controls
21229
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
XCK00
NOMESCO Finland
Perimetry
15.5
323.0
653
593
H47.1
ICD-10 Finland
Papilloedema, unspecified
+∞
323.0
699
*
H47.3
ICD-10 Finland
Other disorders of optic disc
4681.8
323.0
396
*
H47.2
ICD-10 Finland
Optic atrophy
+∞
323.0
536
*
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
7991.4
323.0
595
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.3
203.6
750
1971
H46
ICD-10 Finland
Optic neuritis
+∞
203.5
192
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
7.9
203.3
516
833
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
8.5
168.4
398
561
XCK10
NOMESCO Finland
Photography of fundus of eye
6.3
167.0
502
1001
G93.2
ICD-10 Finland
Benign intracranial hypertension
226.3
163.6
167
8
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
14.1
154.6
274
220
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.2
147.4
438
848
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.5
147.1
495
1116
H53.4
ICD-10 Finland
Visual field defects
17.0
141.8
232
152
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
12.1
118.7
225
206
XCD10
NOMESCO Finland
Electrophysiological examination of eye
12.8
114.9
212
183
TAB00
NOMESCO Finland
Lumbar puncture
8.0
113.5
274
387
S01EC01
ATC
acetazolamide; systemic
13.6
108.9
195
157
CS494
NOMESCO Finland
Other visual field testing
13.2
106.9
194
161
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
25.5
87.0
123
51
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
12.4
84.0
156
135
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
37.0
77.1
99
28
Z3229
NOMESCO Finland
Other healthcare associate professional
4.1
76.3
332
923
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.2
74.3
311
833
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
24.0
71.7
103
45
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
10.1
64.8
133
140
H53.1
ICD-10 Finland
Subjective visual disturbances
4.6
62.4
234
559
G35
ICD-10 Finland
Multiple sclerosis
13.8
61.6
108
82
AA1AD
NOMESCO Finland
CT of head and brain
2.5
61.5
594
2841
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
35.8
58.9
76
22
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
57.6
55
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
8.6
53.3
119
145
109
Kela drug reimbursment
Multiple sclerosis
16.9
49.8
80
49
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
16.1
49.5
81
52
R51.80
ICD-10 Finland
Headache
2.6
47.7
411
1813
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
10.5
45.8
91
90
E23.00
ICD-10 Finland
Panhypopituitarism
25.6
39.4
55
22
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
16.6
39.1
63
39
N86
ICPC
Multiple sclerosis
29.6
38.7
52
18
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
16.1
37.5
61
39
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
31.3
34.8
46
15
37799
ICD-8 Finland
Other diseases of retina and optic nerve, Unspecified
+∞
34.5
33
*
Z3231
NOMESCO Finland
Registered nurse
1.9
33.3
634
3897
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
9.2
33.2
70
78
H53.9
ICD-10 Finland
Visual disturbance, unspecified
5.0
33.1
110
230
ZXA10
NOMESCO Finland
Bilateral
2.1
32.6
432
2303
101
Kela drug reimbursment
Anterior pituitary hypofunction
11.6
32.6
61
54
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
32.5
895
6205
H02AB09
ATC
hydrocortisone; systemic
5.2
32.4
103
205
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
10.4
31.9
63
62
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.5
31.4
281
1244
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.3
31.2
164
520
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
7.7
29.7
70
94
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.4
29.6
284
1298
37790
ICD-8 Finland
Other diseases of retina and optic nerve, Atrophia (et degeneratio) nervi optici (tabica excepta)
+∞
29.2
28
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
24.5
29.2
41
17
N03AX14
ATC
levetiracetam; systemic
4.9
27.9
94
200
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
15.8
27.7
45
29
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.7
26.9
197
777
H47.4
ICD-10 Finland
Disorders of optic chiasm
+∞
26.1
25
*
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
8.3
25.6
57
70
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
10.0
25.5
51
52
G91.1
ICD-10 Finland
Obstructive hydrocephalus
18.0
25.3
39
22
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
8.1
25.2
57
72
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
25.1
783
5507
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
15.5
25.1
41
27
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
24.8
204
859
H02AB06
ATC
prednisolone; systemic
1.6
24.6
923
6818
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
48.9
24.3
29
6
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
5.0
24.3
79
162
XA800
NOMESCO Finland
Neuropsychological investigation
3.3
23.6
121
377
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
11.2
23.4
44
40
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.8
22.9
152
565
G91.0
ICD-10 Finland
Communicating hydrocephalus
12.3
22.8
41
34
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.0
22.8
317
1703
L03AB07
ATC
interferon beta-1a; parenteral
18.2
22.2
34
19
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
15.2
22.0
36
24
H54.4
ICD-10 Finland
Blindness, monocular
25.3
21.8
30
12
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
7.0
21.0
52
76
37791
ICD-8 Finland
Other diseases of retina and optic nerve, Papilloedema. Stasis papillae
+∞
20.9
20
*
H34.1
ICD-10 Finland
Central retinal artery occlusion
12.5
20.8
37
30
PAW37
NOMESCO Finland
Biopsy of temporal artery
9.3
20.8
43
47
L03AX13
ATC
glatiramer acetate; parenteral
19.6
20.8
31
16
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
9.5
20.6
42
45
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
20.3
20.4
30
15
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
8.2
20.2
45
56
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.4
19.9
98
296
H54.7
ICD-10 Finland
Unspecified visual loss
9.9
19.6
39
40
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
6.3
19.3
51
82
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
19.2
333
1932
102
Kela drug reimbursment
Diabetes insipidus
26.3
19.1
26
10
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
18.9
417
2612
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
16.0
18.8
30
19
3771A
ICD-9 Finland
Disorders of optic nerve and visual pathways, Optic atrophy
+∞
18.8
18
*
H47
ICD-10 Finland
Other disorders of optic [2nd] nerve and visual pathways
+∞
18.8
18
*
ZXD05
NOMESCO Finland
Urgent procedure
1.6
18.7
637
4500
L04AX01
ATC
azathioprine; systemic
3.0
18.6
112
390
H54.1
ICD-10 Finland
Severe visual impairment, binocular
23.9
18.6
26
11
D35.30
ICD-10 Finland
Craniopharyngoma
191.6
18.6
19
*
N03AF02
ATC
oxcarbazepine; oral
3.5
18.4
86
250
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
18.3
596
4160
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
13.1
17.9
31
24
XCD20
NOMESCO Finland
Photoangiography of eye
4.9
17.4
57
119
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
17.2
503
3406
A02BC02
ATC
pantoprazole; systemic
1.5
17.2
1219
10102
H40.0
ICD-10 Finland
Glaucoma suspect
2.3
17.2
158
703
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
17.0
543
3761
WX882
NOMESCO Finland
High dependency care
3.3
16.9
87
273
H26.4
ICD-10 Finland
After-cataract
2.2
16.9
171
797
N03AX11
ATC
topiramate; oral
3.9
16.8
70
185
M03BX01
ATC
baclofen; systemic
5.5
16.8
49
90
H47.6
ICD-10 Finland
Disorders of visual cortex
+∞
16.7
16
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.3
16.6
155
696
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
11.7
16.5
30
26
H34.8
ICD-10 Finland
Other retinal vascular occlusions
4.3
16.5
61
145
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
20.2
16.4
24
12
N02BE01
ATC
paracetamol; systemic, rectal
1.6
16.3
1687
15091
Z2446
NOMESCO Finland
Social worker
2.2
16.1
168
793
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
18.7
16.0
24
13
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
9.0
15.9
33
37
N03AX16
ATC
pregabalin; oral
1.6
15.8
431
2858
N05BA09
ATC
clobazam; oral
8.4
15.7
34
41
H53.2
ICD-10 Finland
Diplopia
3.4
15.7
75
223
H01AC01
ATC
somatropin; parenteral
9.8
15.7
31
32
114
Kela drug reimbursment
Glaucoma
2.2
15.6
165
787
S01ED51
ATC
timolol, combinations; ophthalmic
2.3
15.5
143
639
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.0
15.5
62
159
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
9.0
15.4
32
36
H52.1
ICD-10 Finland
Myopia
3.1
15.3
85
283
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.8
15.1
42
73
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
15.1
411
2717
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
15.1
319
1964
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
15.0
212
1138
WX110
NOMESCO Finland
Local anesthesy
1.5
14.9
1356
11645
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
10.1
14.9
29
29
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
14.9
281
1666
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.0
14.9
60
155
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
15.1
14.9
24
16
ZXA00
NOMESCO Finland
Right side
1.6
14.7
496
3458
H03AA01
ATC
levothyroxine sodium; systemic
1.6
14.7
430
2894
Z2445
NOMESCO Finland
Psychologist
2.5
14.7
114
466
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.5
14.7
116
478
L04AX07
ATC
dimethyl fumarate; oral
14.3
14.5
24
17
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.4
14.5
128
560
L04AA27
ATC
fingolimod; oral
36.3
14.4
18
5
N03AG01
ATC
valproic acid; systemic, rectal
2.3
14.4
137
622
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.5
14.4
111
452
3400A
ICD-9 Finland
Multiple sclerosis[SCLEROSIS MULTIPLEX (DISSEMINATA)]
27.4
14.3
19
7
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
5.7
14.2
40
71
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
13.5
14.2
24
18
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
14.2
271
1614
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
14.1
683
5158
H40.11
ICD-10 Finland
Low pressure glaucoma
4.1
14.0
54
134
H54.3
ICD-10 Finland
Mild or no visual impairment, binocular
13.7
13.7
23
17
H57.1
ICD-10 Finland
Ocular pain
3.0
13.7
80
276
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.4
13.6
116
499
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
4.9
13.6
44
92
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.7
13.6
90
337
G47.3
ICD-10 Finland
Sleep apnoea
1.6
13.5
372
2460
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.3
13.4
123
548
164
Kela drug reimbursment
Fingolimod
18.3
13.4
20
11
N05CF01
ATC
zopiclone; oral
1.5
13.1
569
4188
S01EE01
ATC
latanoprost; ophthalmic
2.4
13.1
112
480
R50.9
ICD-10 Finland
Fever, unspecified
1.7
13.1
281
1733
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
16.8
13.0
20
12
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
3.1
12.9
70
230
ZX120
NOMESCO Finland
Intravenous
1.9
12.9
189
1027
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
70.3
12.6
14
*
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
4.2
12.5
47
115
ZXC95
NOMESCO Finland
Use of surgical navigator
5.0
12.5
39
79
H54.0
ICD-10 Finland
Blindness, binocular
20.2
12.4
18
9
G44.2
ICD-10 Finland
Tension-type headache
1.7
12.4
249
1502
A02BC01
ATC
omeprazole; systemic
1.5
12.4
508
3688
H04.10
ICD-10 Finland
Dry eye syndrome
1.9
12.4
187
1027
F05
ICPC
Visual disturbance other
3.0
12.4
71
242
C03CA01
ATC
furosemide; systemic
1.5
12.4
479
3435
XCH00
NOMESCO Finland
Eye pressure measurement
2.7
12.4
85
325
CS2P4
NOMESCO Finland
Optic nerve head imaging
8.0
12.3
27
34
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
11.7
12.3
22
19
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
12.3
269
1668
SPAT1229
SPAT
Assessment of need for aid
2.0
12.3
150
759
N03AX12
ATC
gabapentin; oral
1.7
12.2
283
1784
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
26.8
12.0
16
6
H52.0
ICD-10 Finland
Hypermetropia
3.5
11.9
55
161
J01FF01
ATC
clindamycin; systemic
1.5
11.9
499
3634
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.7
11.8
39
84
N02AX02
ATC
tramadol; systemic, rectal
1.4
11.8
749
5913
H53.8
ICD-10 Finland
Other visual disturbances
5.5
11.8
34
63
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.5
11.7
584
4402
A02BC03
ATC
lansoprazole; oral
1.5
11.7
514
3778
R42
ICD-10 Finland
Dizziness and giddiness
1.6
11.7
385
2654
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.8
11.6
48
128
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
30.2
11.6
15
5
H47.5
ICD-10 Finland
Disorders of other visual pathways
+∞
11.5
11
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
11.4
517
3822
L04AA06
ATC
mycophenolic acid; systemic
3.5
11.4
53
156
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.3
11.4
56
172
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
11.3
763
6079
AA4BG
NOMESCO Finland
MRI examination of sella turcica with high intensity magnet
15.1
11.3
18
12
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
15.1
11.3
18
12
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.4
11.3
98
426
183
Kela drug reimbursment
Lamotrigin and topiramate
5.0
11.2
35
71
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
3.4
11.2
53
159
34099
ICD-8 Finland
Multiple sclerosis
25.1
11.1
15
6
L04AA31
ATC
teriflunomide; oral
20.1
11.1
16
8
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
5.6
11.0
31
56
CKC12
NOMESCO Finland
Photocoagulation of retina
2.5
11.0
88
368
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
3.0
10.9
63
217
J01DA01
ATC
[U] cefalexin; systemic
1.4
10.8
1171
10072
G03.9
ICD-10 Finland
Meningitis, unspecified
12.0
10.8
19
16
P85
ICPC
Mental retardation
15.6
10.8
17
11
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.9
10.8
163
894
H50.1
ICD-10 Finland
Divergent concomitant strabismus
6.5
10.8
27
42
SPAT1153
SPAT
Removal of sutures
1.4
10.7
564
4286
L03AB08
ATC
interferon beta-1b; parenteral
17.9
10.7
16
9
R3120
NOMESCO Finland
Training in mobility skills
17.9
10.7
16
9
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.2
10.7
54
170
AAA27
NOMESCO Finland
Insertion of intracerebral pressure monitoring device
21.6
10.7
15
7
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
10.6
387
2726
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.1
10.6
32
63
A28
ICPC
Limited function/disability NOS
1.7
10.6
246
1549
E66.01
ICD-10 Finland
Obesity due to excess calories
1.9
10.5
151
814
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.4
10.4
692
5479
3774A
ICD-9 Finland
Disorders of optic nerve and visual pathways, Other disorders of optic nerve
+∞
10.4
10
*
36703
ICD-8 Finland
Inflammation of optic nerve and retina, Neuritis optica, retrobulbaris
+∞
10.4
10
*
ZXA05
NOMESCO Finland
Left side
1.5
10.4
440
3199
N04BB01
ATC
amantadine; oral
4.0
10.4
40
101
H54.6
ICD-10 Finland
Moderate visual impairment, monocular
16.1
10.3
16
10
K02.1
ICD-10 Finland
Caries of dentine
1.4
10.3
1068
9092
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.3
10.3
91
398
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
3.7
10.3
44
122
D44.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pituitary gland
10.6
10.3
19
18
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
4.0
10.2
39
98
WX892
NOMESCO Finland
Monitored bed care
1.9
10.2
143
767
S01EC04
ATC
brinzolamide; ophthalmic
2.7
10.2
69
264
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.1
10.2
54
177
C07AB07
ATC
bisoprolol; oral
1.4
10.1
794
6461
A06AD11
ATC
lactulose; oral
1.6
10.1
243
1543
353
Kela drug reimbursment
Cladribine and fingolimod
14.6
10.0
16
11
R4120
NOMESCO Finland
Occupational therapy
2.0
10.0
123
629
UKC02
NOMESCO Finland
Cystoscopy
1.6
9.9
266
1740
AA1AA
NOMESCO Finland
Head X-ray examination
5.4
9.8
28
52
C08CA01
ATC
amlodipine; oral
1.4
9.8
585
4540
H02AB04
ATC
methylprednisolone; systemic
1.6
9.8
255
1655
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
55.2
9.6
11
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
9.5
771
6285
N03AX18
ATC
lacosamide; systemic
5.7
9.5
26
46
S18
ICPC
Laceration/cut
1.4
9.5
744
6040
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
9.4
399
2897
D32.03
ICD-10 Finland
Benign meningioma in ventricles
30.1
9.4
12
*
AAF15
NOMESCO Finland
Ventriculoatrial shunt
17.6
9.4
14
8
2132
FHL
Ventricular operators sunt
+∞
9.4
9
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
9.4
604
4741
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
5.9
9.4
25
43
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
9.3
511
3897
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
9.3
984
8349
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
9.3
518
3959
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
6.4
9.2
23
36
SPAT1301
SPAT
No procedures
1.4
9.2
581
4540
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.9
9.2
141
780
R4190
NOMESCO Finland
Nutritional therapy
2.3
9.2
84
374
Z2221
NOMESCO Finland
Medical doctor
1.4
9.2
516
3951
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.9
9.2
135
738
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.4
9.1
78
337
H53.0
ICD-10 Finland
Amblyopia ex anopsia
4.6
9.1
30
66
Z3226
NOMESCO Finland
Physiotherapist
1.5
9.1
347
2464
C10AA01
ATC
simvastatin; oral
1.4
9.1
687
5532
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
5.4
9.1
26
49
G40.10
ICD-10 Finland
Simple partial seizures
5.9
9.0
24
41
AWB00
NOMESCO Finland
Reoperation for superficial infection in surgery of the nervous system
15.7
9.0
14
9
G93.0
ICD-10 Finland
Cerebral cysts
9.1
9.0
18
20
R01AD09
ATC
mometasone; nasal
1.3
9.0
803
6631
XCW12
NOMESCO Finland
Assessment of colour vision
36.8
9.0
11
*
AAF10
NOMESCO Finland
Lumboperitoneal shunt
36.8
9.0
11
*
E89.30
ICD-10 Finland
Postprocedural hypopituitarism
36.8
9.0
11
*
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
4.1
9.0
33
81
E23.2
ICD-10 Finland
Diabetes insipidus
18.7
8.9
13
7
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.8
8.9
36
96
2AB04
NOMESCO Finland
NA
24.1
8.9
12
5
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.2
8.8
87
404
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
8.8
120
637
ZXD10
NOMESCO Finland
Scheduled procedure
1.3
8.8
698
5660
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
8.7
1035
8901
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.4
8.7
73
315
N03AF01
ATC
carbamazepine; oral, rectal
2.1
8.7
96
470
3313A
ICD-9 Finland
Other cerebral degenerations, Communicating hydrocephalus
50.2
8.7
10
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.9
8.7
117
620
XKD00
NOMESCO Finland
Uroflowmetry
1.6
8.7
254
1700
H34.2
ICD-10 Finland
Other retinal artery occlusions
6.6
8.7
21
32
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.6
1333
11899
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.3
8.6
41
125
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
8.6
181
1105
R33
ICD-10 Finland
Retention of urine
1.9
8.5
126
690
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.0
8.5
26
53
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
4.3
8.5
30
71
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
4.3
8.5
30
71
WX140
NOMESCO Finland
Parabulbar anesthesy
2.3
8.5
75
333
G91.8
ICD-10 Finland
Other hydrocephalus
27.6
8.5
11
*
TK800
NOMESCO Finland
Hemodialysis
3.0
8.5
46
155
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
90.4
8.4
9
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.8
8.4
53
194
3770A
ICD-9 Finland
Disorders of optic nerve and visual pathways, Papilloedema
+∞
8.3
8
*
3772A
ICD-9 Finland
Disorders of optic nerve and visual pathways, Other disorders of optic disk
+∞
8.3
8
*
9350/1-C75.2
ICD-O-3
Craniopharyngioma, NOS, of craniopharyngeal duct
+∞
8.3
8
*
H48.1*G35
ICD-10 Finland
Retrobulbar neuritis in multiple sclerosis
+∞
8.3
8
*
RS222
NOMESCO Finland
NA
3.7
8.3
34
92
Z49.1
ICD-10 Finland
Extracorporeal dialysis
3.7
8.3
34
92
R11
ICD-10 Finland
Nausea and vomiting
1.8
8.3
148
863
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
4.3
8.3
29
68
RK110
NOMESCO Finland
NA
4.6
8.3
27
59
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
9.5
8.3
16
17
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
8.3
374
2747
M79.6
ICD-10 Finland
Pain in limb
1.3
8.2
612
4903
L28
ICPC
Limited function/disability (L)
1.5
8.2
253
1715
J01MA02
ATC
ciprofloxacin; systemic
1.3
8.2
658
5330
H52.2
ICD-10 Finland
Astigmatism
3.3
8.2
39
120
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.9
8.2
117
635
AAF00
NOMESCO Finland
Ventriculostomy
7.6
8.2
18
24
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
8.2
153
904
WX290
NOMESCO Finland
Other blockade of nerve
1.3
8.1
793
6612
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
17.2
8.1
12
7
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
17.2
8.1
12
7
M31.6
ICD-10 Finland
Other giant cell arteritis
11.7
8.1
14
12
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.5
8.1
35
100
R01AD08
ATC
fluticasone; nasal
1.4
8.0
489
3784
H50.0
ICD-10 Finland
Convergent concomitant strabismus
5.0
8.0
24
48
J01AA02
ATC
doxycycline; systemic
1.3
8.0
1427
12929
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
4.3
8.0
28
66
J01DB01
ATC
cefalexin; oral
1.3
8.0
1583
14565
R60.0
ICD-10 Finland
Localized oedema
1.6
8.0
183
1149
WX704
NOMESCO Finland
Intubation
1.8
8.0
125
700
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
7.9
283
1979
WX872
NOMESCO Finland
Intensive care
2.1
7.9
88
432
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
7.9
207
1343
S01ED01
ATC
timolol; ophthalmic
2.4
7.9
62
260
SPAT1216
SPAT
Assessment of functional ability
1.5
7.9
251
1709
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
7.8
67
292
ZXE00
NOMESCO Finland
One hour or less
1.3
7.8
724
5979
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
5.7
7.8
21
37
R62.0
ICD-10 Finland
Delayed milestone
4.3
7.8
27
63
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
45.1
7.7
9
*
181
Kela drug reimbursment
Retigabine and vigabatrin
15.1
7.7
12
8
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.2
7.7
77
363
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.1
7.7
88
437
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
5.9
7.7
20
34
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
7.4
7.7
17
23
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.1
7.6
84
413
A02BA02
ATC
ranitidine; systemic
1.4
7.6
322
2330
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
2.7
7.6
49
184
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
7.6
1221
10862
Q85.00
ICD-10 Finland
Neurofibromatosis, type 1
11.9
7.6
13
11
N07XX09
ATC
[U] dimethyl fumarate; oral
11.9
7.6
13
11
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.1
7.5
81
394
301
Kela drug reimbursment
Growth hormone
10.1
7.5
14
14
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.8
7.5
20
35
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.7
7.5
48
179
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
3.0
7.5
41
140
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
7.5
252
1738
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
7.5
939
8080
E66.8
ICD-10 Finland
Other obesity
2.0
7.5
93
478
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
7.4
105
567
G80.8
ICD-10 Finland
Other cerebral palsy
80.4
7.4
8
*
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
3.4
7.4
33
97
M05BA04
ATC
alendronic acid; oral
1.8
7.4
127
733
H50.30
ICD-10 Finland
Intermittent esotropy
6.0
7.4
19
32
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
7.3
477
3727
N06AX21
ATC
duloxetine; oral
1.6
7.3
181
1159
H02AB07
ATC
prednisone; oral
1.5
7.3
236
1612
A10AE04
ATC
insulin glargine; parenteral
1.7
7.3
157
969
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
7.3
725
6038
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.5
7.3
54
218
G96.0
ICD-10 Finland
Cerebrospinal fluid leak
10.9
7.3
13
12
F83
ICD-10 Finland
Mixed specific developmental disorders
4.2
7.3
26
63
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.5
7.3
217
1457
A11CC03
ATC
alfacalcidol; systemic
2.6
7.2
50
194
Z94.0
ICD-10 Finland
Kidney transplant status
3.4
7.2
32
94
N03AB02
ATC
phenytoin; systemic
3.5
7.2
31
89
M03BX02
ATC
tizanidine; oral
1.3
7.2
1082
9511
R4110
NOMESCO Finland
Physiotherapy
1.4
7.2
460
3586
SPAT1254
SPAT
Administration of medicine
1.5
7.1
269
1899
9380/3-C71.9
ICD-O-3
Glioma, malignant of brain, NOS
30.1
7.1
9
*
H25.0
ICD-10 Finland
Senile incipient cataract
1.9
7.1
95
503
M41.4
ICD-10 Finland
Neuromuscular scoliosis
20.1
7.1
10
5
G40.21
ICD-10 Finland
Partial epileptic seizure with cloudiness and automatism
6.6
7.1
17
26
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
5.0
7.1
21
42
H25.8
ICD-10 Finland
Other senile cataract
1.6
7.1
163
1023
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.2
7.1
25
60
G81.9
ICD-10 Finland
Hemiplegia, unspecified
4.2
7.1
25
60
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
7.1
298
2153
N03AX09
ATC
lamotrigine; oral
2.0
7.1
90
467
AA1AM
NOMESCO Finland
Short MRI examination of brain with 3 Tesla magnet
12.1
7.1
12
10
N03AE01
ATC
clonazepam; systemic
1.9
7.1
102
554
N05BA01
ATC
diazepam; systemic, rectal
1.5
7.1
220
1490
M04AA01
ATC
allopurinol; systemic
1.6
7.0
199
1319
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.9
7.0
104
574
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.8
7.0
111
624
N05BA04
ATC
oxazepam; oral
1.4
6.9
415
3198
V03AE02
ATC
sevelamer; oral
5.5
6.9
19
35
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
5.8
6.9
18
31
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
6.9
183
1196
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
6.8
233
1615
RT150
NOMESCO Finland
NA
5.0
6.8
20
40
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
9.3
6.8
13
14
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
6.8
626
5149
2133
FHL
Suntin revisio
40.2
6.8
8
*
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
2.7
6.8
44
167
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.1
6.7
68
323
N28
ICPC
Limited function/disability (N)
3.3
6.7
31
94
N06AX11
ATC
mirtazapine; oral
1.3
6.7
532
4278
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
6.7
296
2156
B03XA02
ATC
darbepoetin alfa; parenteral
2.9
6.7
39
138
WX002
NOMESCO Finland
Sedation and analgesia
1.4
6.7
327
2429
CKC15
NOMESCO Finland
Panretinal photocoagulation
4.1
6.7
24
59
E23.06
ICD-10 Finland
Empty sella
22.6
6.7
9
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
6.7
146
906
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
3.9
6.7
25
64
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.4
6.6
22
50
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
6.6
731
6155
G40.89
ICD-10 Finland
Other epilepsy
5.9
6.6
17
29
C10AA05
ATC
atorvastatin; oral
1.3
6.6
590
4825
M05BX04
ATC
denosumab; parenteral
2.0
6.6
78
395
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.5
6.6
254
1804
N03AG04
ATC
vigabatrin; oral
12.3
6.6
11
9
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
12.3
6.6
11
9
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
12.3
6.6
11
9
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.4
6.5
50
208
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
6.5
382
2930
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
6.5
98
543
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
6.5
393
3028
S01EE04
ATC
travoprost; ophthalmic
2.7
6.5
40
148
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
6.9
6.5
15
22
H35.9
ICD-10 Finland
Retinal disorder, unspecified
6.9
6.5
15
22
127
Kela drug reimbursment
Transplant complication
2.8
6.5
39
142
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
4.0
6.5
24
61
N05AH04
ATC
quetiapine; oral
1.4
6.5
278
2016
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
5.3
6.5
18
34
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
5.3
6.5
18
34
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
6.5
420
3274
H54.5
ICD-10 Finland
Severe visual impairment, monocular
5.7
6.4
17
30
Q85.0
ICD-10 Finland
Neurofibromatosis (nonmalignant)
70.0
6.4
7
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
7.4
6.4
14
19
205
Kela drug reimbursment
Chronic hypertension
1.3
6.4
434
3408
NDG79
NOMESCO Finland
Other excision, reconstruction or fusion of joint of II-V finger
14.3
6.4
10
7
F02.89*G35
ICD-10 Finland
Dementia in multiple sclerosis
14.3
6.4
10
7
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
3.6
6.4
26
72
S01EE03
ATC
bimatoprost; ophthalmic
2.7
6.3
41
154
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
6.3
304
2250
RD210
NOMESCO Finland
NA
2.5
6.3
48
197
N18.8
ICD-10 Finland
Other chronic renal failure
2.4
6.3
51
217
A10AE05
ATC
insulin detemir; parenteral
1.8
6.3
98
550
RL140
NOMESCO Finland
NA
6.0
6.3
16
27
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.5
6.3
17
31
D33.30
ICD-10 Finland
Acoustic neuroma
5.5
6.3
17
31
G97.1
ICD-10 Finland
Other reaction to spinal and lumbar puncture
11.0
6.3
11
10
Z31.5
ICD-10 Finland
Genetic counselling
1.9
6.3
88
475
V03AE01
ATC
polystyrene sulfonate; oral
3.6
6.3
26
73
L03AB13
ATC
peginterferon beta-1a; parenteral
18.1
6.3
9
5
C72.3
ICD-10 Finland
Malignant neoplasm: Optic nerve
+∞
6.3
6
*
3773B
ICD-9 Finland
Disorders of optic nerve and visual pathways, Optic neuritis[NEURITIS RETROBULBARIS]
+∞
6.3
6
*
G36.0
ICD-10 Finland
Neuromyelitis optica [Devic]
26.7
6.2
8
*
C71.00
ICD-10 Finland
Malignant tumor of the cerebrum except lobes and ventricles without histology
26.7
6.2
8
*
R53
ICD-10 Finland
Malaise and fatigue
1.4
6.2
351
2674
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
6.2
140
877
RS140
NOMESCO Finland
NA
7.0
6.2
14
20
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.5
6.2
44
175
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.6
6.2
138
861
-
ICD-10 Finland
NA
2.5
6.2
44
176
H02AB02
ATC
dexamethasone; systemic
1.6
6.2
160
1041
WF099
NOMESCO Finland
Other radiotherapy
6.3
6.2
15
24
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.6
6.2
136
846
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.0
6.2
32
107
ZXC86
NOMESCO Finland
Use of endoscopic device
5.3
6.1
17
32
N06AA09
ATC
amitriptyline; systemic
1.6
6.1
161
1050
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
2.6
6.1
41
160
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
6.1
504
4072
WX725
NOMESCO Finland
Noninvasive ventilation
1.9
6.1
77
403
M01AX17
ATC
nimesulide; oral
1.4
6.1
379
2932
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
4.0
6.1
22
55
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
6.1
370
2856
G50.0
ICD-10 Finland
Trigeminal neuralgia
3.1
6.1
30
97
186
Kela drug reimbursment
Growth retardation associated with renal failure (growth hormone)
8.6
6.1
12
14
ZXE21
NOMESCO Finland
Procedure duration at least 3 but less than 4 hours
4.9
6.0
18
37
ZXC40
NOMESCO Finland
Use of ultrasound
4.4
6.0
20
46
A02BC05
ATC
esomeprazole; systemic
1.3
6.0
668
5608
ZXE30
NOMESCO Finland
More than five and less than seven hours
1.8
6.0
92
514
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
4.1
6.0
21
51

Mortality – FinRegistry

Association

Association between endpoint H7_OPTNEUROTH and mortality.

Females

Parameter HR [95% CI] p-value
H7_OPTNEUROTH 1.58 [1.41, 1.77] < 0.001
Birth year 0.99 [0.98, 1.0] 0.022

During the follow-up period (1.1.1998 — 31.12.2019), 1306 out of 7603 females with H7_OPTNEUROTH died.

Males

Parameter HR [95% CI] p-value
H7_OPTNEUROTH 1.77 [1.58, 1.98] < 0.001
Birth year 0.989 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 1541 out of 6538 males with H7_OPTNEUROTH died.

Mortality risk

Mortality risk for people of age

years, who have H7_OPTNEUROTH.

N-year risk Females Males
1 0.134% 0.413%
5 0.666% 2.349%
10 1.952% 5.49%
15 3.891% 10.277%
20 6.709% 16.732%

Relationships between endpoints

Index endpoint: H7_OPTNEUROTH – Other disorders of optic [2nd] nerve and visual pathways

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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