optic papillitis: Swelling of the optic disk, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause optic atrophy and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
886 |
4. Check minimum number of eventsNone |
886 |
5. Include endpointsNone |
886 |
6. Filter based on genotype QC (FinnGen only) |
849 |
Control definitions (FinnGen only)
- Control exclude
- H7_OPTNERVE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H47
- Name in latin
- Oedema papillae non specificatum
Similar endpoints
↥List of similar endpoints to
Papilloedema, unspecified
based on the number of shared cases.
Similar with more cases:
- Other disorders of optic [2nd] nerve and visual pathways
- Disorders of optic nerve and visual pathways
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5484 | 3197 | 2258 |
| Only index persons | 4991 | 2970 | 2021 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.09 | 0.06 |
| Only index persons | 0.10 | 0.11 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 42.25 | 38.70 | 47.19 |
| Only index persons | 41.63 | 37.90 | 47.11 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 849 | 543 | 306 |
| Unadjusted period prevalence (%) | 0.17 | 0.19 | 0.14 |
| Median age at first event (years) | 47.60 | 42.27 | 57.05 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 886
- Matched controls
- 8860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H47.1
ICD-10 Finland
Papilloedema, unspecified
4503599627370496.0
307.7
854
*
S01EC01
ATC
acetazolamide; systemic
34.6
299.7
198
73
XCK00
NOMESCO Finland
Perimetry
17.0
251.5
232
181
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
14.0
220.1
228
214
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
11.1
217.4
277
350
G93.2
ICD-10 Finland
Benign intracranial hypertension
806.3
201.7
191
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
18.1
174.9
149
98
TAB00
NOMESCO Finland
Lumbar puncture
12.1
167.3
186
191
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
16.9
154.3
135
93
Z01.0
ICD-10 Finland
Examination of eyes and vision
6.1
146.9
368
930
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
+∞
138.2
129
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
7.4
128.8
220
379
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
20.1
128.8
102
57
XCK10
NOMESCO Finland
Photography of fundus of eye
6.9
114.3
205
369
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.4
110.2
215
420
H47.3
ICD-10 Finland
Other disorders of optic disc
1011.1
94.7
91
*
CS494
NOMESCO Finland
Other visual field testing
13.6
84.9
82
66
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
41.6
83.9
51
13
H46
ICD-10 Finland
Optic neuritis
+∞
80.5
76
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
11.8
70.3
74
68
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
12.4
65.2
66
57
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
22.5
63.4
47
22
H53.4
ICD-10 Finland
Visual field defects
12.7
62.3
62
52
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.4
56.9
166
444
H47.2
ICD-10 Finland
Optic atrophy
+∞
56.9
54
*
H53.1
ICD-10 Finland
Subjective visual disturbances
5.1
52.0
121
269
R51.80
ICD-10 Finland
Headache
3.1
45.3
241
949
AA1AD
NOMESCO Finland
CT of head and brain
2.9
43.7
288
1273
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
8.7
43.2
56
68
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
16.5
41.1
35
22
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
9.1
33.0
41
47
TAB22
NOMESCO Finland
Stoppin epidural fluid escape with coagulated blood
9.0
30.3
38
44
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
11.9
30.2
31
27
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
41.7
29.2
36
9
L04AA06
ATC
mycophenolic acid; systemic
6.9
24.8
39
59
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.2
24.3
106
364
37791
ICD-8 Finland
Other diseases of retina and optic nerve, Papilloedema. Stasis papillae
+∞
24.1
23
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
23.6
401
2544
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
23.5
216
1078
H02AB06
ATC
prednisolone; systemic
2.0
23.2
437
2872
H34.8
ICD-10 Finland
Other retinal vascular occlusions
6.9
23.1
36
54
L04AX01
ATC
azathioprine; systemic
4.1
21.5
61
157
Z3229
NOMESCO Finland
Other healthcare associate professional
3.1
21.3
96
335
N03AX11
ATC
topiramate; oral
4.7
21.0
50
112
A02BC02
ATC
pantoprazole; systemic
2.0
20.3
581
4335
E66.8
ICD-10 Finland
Other obesity
3.4
19.5
75
238
PAW37
NOMESCO Finland
Biopsy of temporal artery
47.1
19.3
23
5
E66.01
ICD-10 Finland
Obesity due to excess calories
2.7
19.2
116
474
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.6
19.1
66
195
H02AB09
ATC
hydrocortisone; systemic
5.3
19.0
39
77
L04AD02
ATC
tacrolimus; systemic
8.3
18.8
25
31
XCD20
NOMESCO Finland
Photoangiography of eye
7.8
18.8
26
34
127
Kela drug reimbursment
Transplant complication
6.3
18.2
31
51
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.9
17.7
32
56
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
13.5
17.5
30
23
Z94.0
ICD-10 Finland
Kidney transplant status
7.9
17.5
24
31
N03AX14
ATC
levetiracetam; systemic
4.9
17.4
39
83
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
14.2
17.4
29
21
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
12.9
17.2
30
24
C03CA01
ATC
furosemide; systemic
2.0
16.4
219
1246
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
16.3
137
651
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
30.7
16.2
21
7
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
48.4
16.1
19
*
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
13.9
16.1
27
20
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.9
14.8
71
256
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
3.7
14.8
48
136
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
25.5
14.7
20
8
B03XA02
ATC
darbepoetin alfa; parenteral
5.7
14.4
27
49
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
19.5
14.3
21
11
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.6
14.2
47
135
G47.3
ICD-10 Finland
Sleep apnoea
2.0
14.2
195
1115
H43.1
ICD-10 Finland
Vitreous haemorrhage
5.0
13.9
30
62
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
54.2
13.8
16
*
ZXA10
NOMESCO Finland
Bilateral
2.0
13.5
163
888
Z3231
NOMESCO Finland
Registered nurse
1.8
13.5
248
1553
N18.8
ICD-10 Finland
Other chronic renal failure
5.3
13.5
27
52
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
13.4
142
737
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.4
13.4
48
145
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
11.7
13.4
24
21
H53.2
ICD-10 Finland
Diplopia
3.7
12.8
41
115
XCH00
NOMESCO Finland
Eye pressure measurement
3.4
12.7
47
145
G44.2
ICD-10 Finland
Tension-type headache
2.0
12.6
144
768
N02BE01
ATC
paracetamol; systemic, rectal
2.1
12.5
769
6728
N02AX02
ATC
tramadol; systemic, rectal
1.7
12.3
343
2411
TK800
NOMESCO Finland
Hemodialysis
5.0
12.2
26
53
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.6
12.2
23
42
J01FF01
ATC
clindamycin; systemic
1.8
11.9
233
1482
H02AB02
ATC
dexamethasone; systemic
2.3
11.7
98
463
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.8
11.6
59
220
A02BC01
ATC
omeprazole; systemic
1.8
11.6
233
1492
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
11.4
248
1622
ZX120
NOMESCO Finland
Intravenous
2.3
11.3
89
409
H52.0
ICD-10 Finland
Hypermetropia
4.4
11.3
28
65
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
5.6
11.2
21
38
G03.9
ICD-10 Finland
Meningitis, unspecified
25.4
11.2
15
6
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
11.1
192
1174
CKC12
NOMESCO Finland
Photocoagulation of retina
3.2
11.0
44
143
E23.06
ICD-10 Finland
Empty sella
43.9
10.9
13
*
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
9.7
10.8
21
22
F05
ICPC
Visual disturbance other
3.4
10.6
39
120
AAA27
NOMESCO Finland
Insertion of intracerebral pressure monitoring device
60.7
10.6
12
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
11.4
10.6
19
17
AAF10
NOMESCO Finland
Lumboperitoneal shunt
+∞
10.4
10
*
C08CA01
ATC
amlodipine; oral
1.7
10.1
263
1796
R4190
NOMESCO Finland
Nutritional therapy
2.9
10.0
46
162
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
40.5
10.0
12
*
H36.01
ICD-10 Finland
Diabetic maculopathy
5.2
9.9
20
39
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
20.3
9.8
14
7
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
9.7
326
2365
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
9.7
124
686
WX704
NOMESCO Finland
Intubation
2.3
9.6
72
324
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
9.6
632
5352
WX882
NOMESCO Finland
High dependency care
3.7
9.6
30
83
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.1
9.6
20
40
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
15.2
9.5
15
10
XCW12
NOMESCO Finland
Assessment of colour vision
101.1
9.4
10
*
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
9.4
315
2281
3770A
ICD-9 Finland
Disorders of optic nerve and visual pathways, Papilloedema
+∞
9.4
9
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
8.8
9.3
19
22
PA2AD
NOMESCO Finland
CT angiography of brain
10.8
9.3
17
16
A10AB05
ATC
insulin aspart; parenteral
2.3
9.3
72
329
H57.1
ICD-10 Finland
Ocular pain
2.8
9.2
46
170
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
7.8
9.2
20
26
CA1DG
NOMESCO Finland
Eye and orbita very extensive MRI examination with high intensity magnet
37.1
9.0
11
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
8.9
347
2595
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.0
8.9
98
515
WX725
NOMESCO Finland
Noninvasive ventilation
2.6
8.9
51
203
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.4
8.8
32
98
SPAT1153
SPAT
Removal of sutures
1.6
8.8
243
1677
WX872
NOMESCO Finland
Intensive care
2.7
8.7
45
170
H02AB04
ATC
methylprednisolone; systemic
1.9
8.6
118
668
G91.1
ICD-10 Finland
Obstructive hydrocephalus
11.7
8.6
15
13
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
8.5
406
3162
R42
ICD-10 Finland
Dizziness and giddiness
1.7
8.5
172
1094
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
8.4
107
591
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
8.6
8.3
17
20
L01AX03
ATC
temozolomide; systemic
14.6
8.2
13
9
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
8.2
99
537
R50.9
ICD-10 Finland
Fever, unspecified
1.8
8.2
134
801
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.8
8.1
24
64
G91.0
ICD-10 Finland
Communicating hydrocephalus
11.8
8.1
14
12
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
10.1
8.0
15
15
R01AD08
ATC
fluticasone; nasal
1.6
8.0
239
1672
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.2
8.0
21
51
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
7.9
208
1412
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.7
7.9
18
39
C07AB07
ATC
bisoprolol; oral
1.5
7.9
333
2518
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.5
7.8
50
210
SPAT1263
SPAT
Sampling
1.5
7.8
358
2754
ZXD05
NOMESCO Finland
Urgent procedure
1.6
7.7
259
1860
SPAT1260
SPAT
Consultation of another employee
1.7
7.7
147
917
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.5
7.7
49
205
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
8.1
7.6
16
20
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
18.5
7.6
11
6
N03AF02
ATC
oxcarbazepine; oral
2.8
7.6
36
130
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.7
7.5
23
63
CS2P4
NOMESCO Finland
Optic nerve head imaging
7.7
7.4
16
21
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
7.4
213
1477
SFA30
NOMESCO Finland
Three-surface restoration
1.5
7.3
332
2537
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
11.0
7.3
13
12
JL9AE
NOMESCO Finland
Ultrasound examination of pancreas transplant
+∞
7.3
7
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
9.5
7.3
14
15
E66.9
ICD-10 Finland
Obesity, unspecified
2.6
7.3
42
168
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
7.3
174
1153
N06AA09
ATC
amitriptyline; systemic
2.1
7.2
73
371
B01AB05
ATC
enoxaparin; parenteral
1.6
7.2
230
1630
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
7.2
85
457
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
3.0
7.2
31
106
R01AD09
ATC
mometasone; nasal
1.5
7.1
386
3052
B05DA
ATC
Isotonic solutions
8.0
7.1
15
19
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
7.1
186
1260
D33.30
ICD-10 Finland
Acoustic neuroma
8.9
7.1
14
16
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.7
7.1
22
61
G35
ICD-10 Finland
Multiple sclerosis
4.3
7.0
18
43
137
Kela drug reimbursment
Uraemia requiring dialysis
7.1
7.0
16
23
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.9
7.0
20
52
JN4AD
NOMESCO Finland
Body CT examination
2.1
7.0
70
355
A12AA04
ATC
calcium carbonate; oral
4.4
7.0
17
39
V03AE01
ATC
polystyrene sulfonate; oral
6.4
7.0
17
27
Z49.1
ICD-10 Finland
Extracorporeal dialysis
6.4
7.0
17
27
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
6.9
172
1148
R20.2
ICD-10 Finland
Paraesthesia of skin
2.1
6.9
65
322
V03AE02
ATC
sevelamer; oral
13.9
6.9
11
8
J01MA12
ATC
levofloxacin; systemic
1.7
6.9
136
856
WX402
NOMESCO Finland
General anaesthesia
1.6
6.9
172
1151
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
2.3
6.9
52
236
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
3.8
6.8
20
53
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.2
6.8
26
83
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
16.8
6.8
10
6
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
3.4
6.7
24
73
G97.1
ICD-10 Finland
Other reaction to spinal and lumbar puncture
22.7
6.7
9
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
6.7
38
151
XX3DW
NOMESCO Finland
Time consuming IT work
1.9
6.6
82
448
H02AB07
ATC
prednisone; oral
1.8
6.6
104
613
N03AX16
ATC
[U] pregabalin
1.6
6.6
174
1177
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
6.6
75
398
XA800
NOMESCO Finland
Neuropsychological investigation
2.5
6.6
41
170
SPAT1301
SPAT
No procedures
1.5
6.6
254
1870
B05DB
ATC
Hypertonic solutions
8.8
6.6
13
15
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.7
6.5
34
129
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
10.1
6.5
12
12
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
10.1
6.5
12
12
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.1
6.5
27
90
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.5
6.5
41
171
J01AA02
ATC
doxycycline; systemic
1.5
6.5
605
5261
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
5.4
6.5
18
34
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
5.8
6.5
17
30
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
6.5
175
1192
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.4
280
2111
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
70.3
6.4
7
*
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
7.5
6.4
14
19
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
14.4
6.4
10
7
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
6.4
61
304
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.4
307
2360
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.7
6.4
33
125
A10AE04
ATC
insulin glargine; parenteral
1.9
6.4
77
418
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
6.6
6.4
15
23
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
8.2
6.3
13
16
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
6.3
316
2445
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
9.3
6.3
12
13
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
3.9
6.3
18
47
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
6.3
101
600
M31.6
ICD-10 Finland
Other giant cell arteritis
18.2
6.3
9
5
AAF15
NOMESCO Finland
Ventriculoatrial shunt
18.2
6.3
9
5
PH4YT
NOMESCO Finland
Dilatation of vein of head or brain
+∞
6.3
6
*
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
26.9
6.2
8
*
G91.8
ICD-10 Finland
Other hydrocephalus
26.9
6.2
8
*
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.7
6.2
19
52
ZXC95
NOMESCO Finland
Use of surgical navigator
5.1
6.2
18
36
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
6.2
262
1962
A11CC03
ATC
alfacalcidol; systemic
3.3
6.2
23
72
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.4
6.2
17
32
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.5
6.1
37
152
E23.00
ICD-10 Finland
Panhypopituitarism
12.6
6.1
10
8
B01AB04
ATC
dalteparin; parenteral
2.4
6.1
41
177
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
8.7
6.1
12
14
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
8.7
6.1
12
14
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.2
6.0
23
73
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
202
182
14.08
199.26
1.4
1.4
462.00
455.70
mg/l
0.03
194
172
185
168
13.65
180.95
1.3
1.4
3.63
3.72
mmol/l
0.39
171
158
170
169
12.21
155.96
1.5
1.3
21.79
11.84
e6/l
0.37
140
134
170
169
12.21
155.96
1.6
1.4
290.11
747.17
e6/l
0.32
142
138
95
64
16.51
109.08
1.2
1.1
55.38
41.27
mg/l
0.34
74
52
93
61
16.92
108.27
1.2
1.0
350.95
231.46
mg/l
0.49
75
54
83
47
19.38
103.78
1.3
1.0
1.10
1.08
u/l
0.08
41
25
99
84
13.14
99.49
1.1
1.1
—
—
—
0
0
87
59
16.24
99.39
1.1
1.0
—
—
—
0
0
96
80
13.34
97.51
1.1
1.1
—
—
—
0
0
89
73
13.44
91.17
1.1
1.1
—
—
—
0
0
137
272
5.78
67.49
2.9
2.1
39.14
38.83
u/l
0.06
124
248
184
499
4.39
62.30
2.7
2.3
25.17
20.22
au/ml
—
9
39
56
67
8.85
43.74
1.3
1.2
—
—
—
0
0
169
556
3.52
42.45
2.7
2.6
9.44
10.36
g/l
2.65
148
511
613
3978
2.76
42.44
7.1
4.9
6.62
6.53
mmol/l
0.43
583
3660
84
171
5.32
39.72
2.6
2.2
10.46
11.83
mg/l
0.78
79
159
517
3163
2.52
39.20
11.0
6.9
1.21
1.22
mmol/l
2.25
445
2698
468
2747
2.49
38.67
7.1
4.7
35.94
36.22
g/l
0.50
442
2562
229
988
2.78
35.47
2.6
2.2
29.88
29.63
s
0.14
220
964
352
1887
2.44
34.54
2.4
2.1
251.08
273.83
u/l
0.07
336
1780
472
2878
2.37
34.51
9.9
6.5
1.20
1.22
mmol/l
2.33
439
2626
177
674
3.03
34.44
2.5
2.1
382.42
376.68
nmol/l
0.12
171
620
462
2845
2.30
32.30
11.6
11.5
1.16
1.18
inr
0.26
134
890
32
31
10.67
29.04
1.5
1.4
—
—
—
0
0
29
32
9.34
23.95
1.1
1.0
—
—
—
0
0
28
30
9.61
23.63
2.0
2.5
547.50
725.03
u/ml
0.50
28
30
183
851
2.45
23.37
10.3
6.1
1.06
1.06
mmol/l
0.06
174
795
570
4155
2.04
22.24
12.0
8.6
4.39
4.02
e9/l
2.87
510
3624
141
596
2.62
21.93
6.9
4.5
0.83
1.80
mmol/l
2.08
106
492
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
32
46
7.18
21.32
1.2
1.2
—
—
—
0
0
373
2372
1.99
21.23
3.3
3.4
41.18
49.98
ng/l
0.14
240
1465
90
309
3.13
20.53
10.0
13.1
—
—
—
0
0
144
647
2.46
19.60
8.4
9.4
0.32
0.99
mmol/l
0.94
100
522
27
12
23.16
19.15
1.2
1.2
—
—
—
0
0
128
552
2.54
18.98
14.4
7.4
9.30
8.57
mmol/l
0.59
122
527
662
5228
2.05
18.97
11.5
7.0
79.81
77.45
u/l
0.41
641
4898
29
43
6.94
18.78
1.1
1.1
—
—
—
0
0
142
655
2.39
18.17
8.5
9.3
13.70
12.54
kpa
1.56
134
630
142
655
2.39
18.17
8.5
9.3
4.91
5.10
kpa
1.44
134
627
478
3435
1.85
17.68
8.6
6.0
10.95
11.89
umol/l
0.52
460
3246
109
451
2.62
17.55
1.7
2.8
65.94
66.84
g/l
0.52
101
415
414
2878
1.82
16.76
3.1
2.3
72.80
74.12
nmol/l
0.44
384
2601
192
1034
2.09
16.74
5.5
3.7
0.82
0.82
mmol/l
0.27
186
970
648
5184
1.93
16.47
5.7
3.9
12.78
10.88
mm/h
2.73
613
4790
332
2189
1.83
15.74
3.6
3.1
2.34
2.35
mmol/l
0.42
300
1950
23
12
19.64
15.61
1.1
1.0
16.67
5.89
mg/g
0.62
23
12
819
7213
2.79
15.53
24.0
13.8
139.62
139.57
mmol/l
0.20
808
6998
101
427
2.54
15.52
5.1
5.4
0.51
1.44
mmol/l
1.38
63
310
104
446
2.51
15.51
5.2
5.3
4.97
5.10
kpa
0.85
98
427
272
1699
1.87
15.25
6.3
3.9
95.15
92.69
%
0.85
265
1649
316
2070
1.82
15.19
4.8
2.5
54.84
59.49
u/l
0.81
298
1916
819
7229
2.76
15.15
24.1
13.9
3.94
3.95
mmol/l
0.37
807
6998
87
351
2.64
14.69
6.4
8.6
22.97
24.52
mmol/l
2.16
81
333
472
3519
1.73
14.17
9.3
5.8
26.34
29.06
%
6.96
457
3325
467
3475
1.73
14.08
8.9
5.6
58.97
56.37
%
5.36
450
3280
103
470
2.35
13.36
5.0
4.2
108.65
80.92
ng/l
0.91
88
426
268
1736
1.78
12.99
4.6
3.3
1478.18
251.23
mg/l
1.54
190
1146
131
672
2.11
12.76
4.5
4.1
250.45
250.43
u/l
0.00
124
642
179
1034
1.92
12.48
2.1
1.9
—
—
—
0
0
276
1823
1.75
12.41
5.7
3.9
20.67
10.20
mg/mmol
1.35
194
1180
465
3559
1.65
11.79
4.9
3.4
0.00
0.00
estimate
0.50
107
740
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
49
163
3.12
11.78
5.6
4.6
0.42
0.34
u/ml
0.58
23
86
141
771
1.99
11.49
7.7
6.3
—
—
—
0
0
41
125
3.39
11.34
1.1
1.1
—
—
—
0
0
23
26
9.05
11.30
1.1
1.3
—
—
—
0
0
171
1006
1.87
11.18
3.8
2.3
12.47
13.67
umol/l
1.35
160
938
809
7280
2.28
11.16
21.6
12.4
20.47
22.28
mg/l
0.85
699
5650
245
1612
1.72
10.95
2.0
1.8
1.91
1.04
mg/l
0.57
186
1199
151
860
1.91
10.89
4.0
2.3
22.62
23.58
%
0.36
124
741
19
16
12.11
10.87
1.1
1.2
—
—
—
0
0
19
16
12.11
10.87
1.1
1.1
—
—
—
0
0
250
1659
1.71
10.81
3.5
2.6
2695.36
5576.46
umol/l
0.79
227
1469
76
333
2.40
10.78
9.6
4.6
23.41
23.83
mmol/l
0.61
76
328
102
508
2.14
10.68
7.4
3.3
1.22
1.23
mmol/l
1.45
91
438
159
931
1.86
10.51
3.9
2.3
2.31
2.39
g/l
0.95
149
865
459
3566
1.60
10.46
6.4
4.6
0.00
0.00
estimate
0.50
101
704
42
137
3.17
10.44
10.7
7.0
1414.78
193.11
iu/ml
—
9
18
463
3611
1.59
10.33
4.9
3.4
0.00
0.00
estimate
0.50
103
678
715
6217
1.78
10.26
6.8
5.1
40.04
38.93
mmol/mol
1.97
685
5808
579
4767
1.62
10.24
5.9
4.1
1103.11
2994.75
e6/l
—
9
65
24
54
4.54
10.06
1.1
1.2
—
—
—
0
0
65
276
2.46
9.88
3.7
4.0
54.12
49.09
%
0.88
65
271
22
47
4.77
9.81
2.0
2.9
—
—
—
0
0
290
2050
1.62
9.62
5.1
3.2
7.40
7.95
mmol/l
1.31
255
1756
329
2399
1.59
9.58
5.6
3.1
—
—
—
0
0
265
1837
1.63
9.50
4.9
2.9
0.31
0.42
e6/l
0.52
213
1379
258
1777
1.64
9.48
2.6
2.1
3.21
2.95
mg/l
1.01
234
1535
659
5651
1.65
9.41
4.8
3.9
14.72
14.59
pmol/l
0.70
607
5161
64
281
2.38
9.05
2.1
1.4
10.44
9.23
u/l
0.31
54
228
17
17
10.17
9.05
1.2
1.3
—
—
—
0
0
54
219
2.56
9.04
2.1
1.5
1.25
0.03
iu/ml
—
9
40
284
2025
1.59
8.97
5.5
3.1
30.64
92.86
e6/l
1.16
226
1552
209
1383
1.67
8.92
4.7
2.4
4.67
6.94
e6/l
1.62
189
1237
235
1605
1.63
8.85
3.5
3.2
1523.62
1088.32
ng/l
0.91
198
1329
17
18
9.60
8.80
1.2
1.2
—
—
—
0
0
17
18
9.60
8.80
1.2
1.1
—
—
—
0
0
103
555
1.97
8.69
11.0
8.5
1.36
1.34
mmol/l
0.05
103
545
36
120
3.08
8.67
2.7
2.2
16.87
15.99
%
0.61
25
55
21
49
4.37
8.44
3.3
2.6
—
—
—
0
0
268
1915
1.57
8.27
5.5
3.5
0.00
0.01
estimate
0.88
95
692
15
16
9.51
7.80
1.1
1.3
—
—
—
0
0
123
729
1.80
7.72
2.0
1.8
—
—
—
0
0
427
3422
1.48
7.47
3.3
2.5
—
—
—
0
0
106
607
1.85
7.43
1.2
1.2
133.96
144.78
iu/ml
0.11
40
241
35
126
2.85
7.40
2.3
2.3
127.40
130.24
g/l
0.28
30
94
18
29
6.31
7.26
1.1
1.0
—
—
—
0
0
56
257
2.26
7.19
3.5
3.0
98.77
91.15
%
2.10
56
248
38
146
2.67
7.12
3.6
3.8
56.42
56.23
%
0.03
38
146
43
179
2.47
6.87
2.5
2.9
—
—
—
0
0
52
236
2.28
6.86
1.7
1.8
—
—
—
0
0
168
1118
1.62
6.86
3.7
2.6
1.26
0.88
e6/l
0.58
95
627
119
723
1.75
6.85
2.1
1.7
—
—
—
0
0
194
1339
1.57
6.79
1.7
1.7
42767720.47
23213134.02
pmol/l
0.18
159
1133
49
220
2.30
6.63
1.2
1.1
—
—
—
0
0
90
508
1.86
6.60
2.8
2.2
5701.58
4223.75
u/l
0.24
27
211
12
12
10.12
6.54
7.2
5.5
—
—
—
0
0
31
112
2.83
6.53
7.3
3.2
70.65
63.20
%
1.02
31
112
166
1114
1.60
6.53
2.6
2.7
2.43
2.43
mmol/l
0.29
151
974
351
2759
1.45
6.52
5.1
3.4
—
—
—
0
0
36
141
2.62
6.52
3.3
3.5
3.76
4.26
e9/l
0.81
36
141
36
141
2.62
6.52
9.6
2.0
1.10
0.86
nmol/l
0.91
31
115
39
159
2.52
6.51
1.4
1.2
—
—
—
0
0
738
6697
1.61
6.47
5.7
4.6
1.86
2.03
mu/l
0.45
695
6191
818
7637
1.93
6.42
15.6
9.3
26.74
25.87
u/l
0.53
800
7371
61
305
2.07
6.35
6.2
5.9
24.27
24.59
mmol/l
0.36
55
294
16
27
6.01
6.32
1.2
1.2
—
—
—
0
0
26
87
3.05
6.27
1.8
1.9
—
—
—
0
0
32
122
2.68
6.12
1.4
1.5
—
—
—
0
0
79
440
1.87
6.05
1.8
1.6
—
—
—
0
0
11
11
10.11
6.04
1.2
1.4
—
—
—
0
0
161
1094
1.58
5.98
2.0
1.7
1251.30
1146.78
nmol/l
0.97
132
837
168
1154
1.56
5.95
3.9
3.5
168.13
306.97
ng/l
1.05
120
818
35
142
2.53
5.93
1.8
1.4
10.17
19.78
u/l
2.24
29
122
739
6751
1.57
5.82
5.2
4.0
5.99
5.82
mmol/l
2.52
682
6203
52
253
2.12
5.82
1.9
1.9
—
—
—
0
0
48
227
2.18
5.77
1.6
1.9
1.63
2.96
ug/l
0.44
40
205
38
163
2.39
5.73
2.1
1.6
—
—
—
0
0
30
115
2.67
5.69
1.2
1.1
1.00
70.14
iu/ml
—
6
29
45
209
2.21
5.66
1.6
2.2
998.95
524.13
ug/l
0.29
40
188
303
2367
1.43
5.63
4.4
3.2
29.51
30.77
u/l
0.26
289
2248
51
250
2.10
5.61
2.5
2.3
1.30
1.42
g/l
0.34
44
220
38
165
2.36
5.58
2.2
1.4
125.50
103.65
u/ml
—
8
32
37
159
2.38
5.56
1.4
3.9
26.63
32.47
mg/l
0.65
28
125
37
159
2.38
5.56
1.5
3.9
155.03
93.83
mg/l
0.20
27
126
66
357
1.92
5.54
1.7
1.6
—
—
—
0
0
422
3503
1.39
5.47
3.8
2.8
135.82
99.51
ug/l
2.03
397
3257
31
125
2.53
5.34
1.5
1.2
5.61
6.42
u/ml
0.09
18
55
724
6627
1.51
5.21
18.8
11.0
85.26
87.04
ml/min/173m2
1.07
612
5332
17
49
3.52
5.19
1.2
1.1
1.09
1.06
ratio
—
5
20
144
985
1.55
5.17
2.9
2.4
110.19
106.77
ug/g
0.07
122
770
79
467
1.76
5.01
2.0
2.5
3.52
6.93
ug/l
3.22
73
418
42
200
2.15
5.00
1.2
2.4
—
—
—
0
0
38
174
2.24
4.97
2.3
1.7
—
—
—
0
0
321
2577
1.39
4.96
2.3
1.9
100.68
96.12
pmol/l
0.86
194
1354
9
10
9.08
4.79
1.1
1.4
—
—
—
0
0
9
10
9.08
4.79
1.3
1.7
—
—
—
0
0
15
34
4.47
4.76
1.1
1.1
1282.80
1401.71
miu/ml
0.14
15
34
46
232
2.04
4.73
3.2
2.8
185.36
175.48
%
0.35
46
221
151
1069
1.50
4.60
4.1
2.8
3.13
2.77
e6/l
0.23
78
584
103
672
1.60
4.52
4.1
3.0
—
—
—
0
0
32
142
2.30
4.52
1.3
1.7
—
—
—
0
0
200
1503
1.43
4.47
1.8
1.5
19.83
20.53
nmol/l
0.30
172
1272
12
24
5.05
4.33
2.1
1.9
—
—
—
0
0
37
178
2.13
4.32
2.2
1.7
—
—
—
0
0
8
9
8.96
4.28
1.1
1.6
—
—
—
0
0
75
459
1.69
4.23
2.5
3.5
4.54
4.59
pmol/l
0.15
68
408
68
405
1.74
4.23
1.6
1.4
18.54
22.36
iu/l
0.49
57
340
38
187
2.08
4.20
1.6
1.3
185.57
241.03
u/ml
1.07
30
107
43
222
1.98
4.18
1.4
1.3
—
—
—
0
0
8
10
8.06
4.06
1.1
1.1
—
—
—
0
0
14
42
3.37
4.05
1.1
1.2
—
—
—
0
0
17
58
2.97
4.02
1.8
1.4
—
—
—
0
0
7
7
10.07
4.01
1.0
1.3
—
—
—
0
0
7
7
10.07
4.01
1.3
1.0
—
—
—
0
0
7
7
10.07
4.01
1.3
1.0
—
—
—
0
0
66
398
1.71
3.94
1.5
1.4
—
—
—
0
0
28
125
2.28
3.93
1.5
1.2
2.38
4.77
u/ml
0.59
13
44
8
11
7.33
3.86
1.3
1.4
—
—
—
0
0
222
1738
1.37
3.85
3.2
2.2
—
—
—
0
0
701
6482
1.39
3.84
24.6
14.8
14.82
14.50
%
0.81
691
6376
204
1580
1.38
3.78
4.9
3.5
1.02
1.02
kg/l
0.18
23
218
38
195
1.99
3.78
1.6
1.3
—
—
—
0
0
79
508
1.61
3.71
2.7
2.4
65.42
72.46
ml/min/173m2
0.65
31
199
734
6860
1.41
3.61
4.8
3.9
1.37
1.47
mmol/l
9.81
692
6394
746
6993
1.42
3.59
5.3
4.4
2.73
2.78
mmol/l
0.68
706
6509
21
86
2.48
3.57
2.4
2.2
—
—
—
0
0
110
771
1.49
3.52
5.0
2.9
4.91
8.36
umol/l
4.08
96
652
20
81
2.50
3.48
2.3
1.6
—
—
—
0
0
8
14
5.76
3.34
1.3
1.1
—
—
—
0
0
208
1646
1.34
3.33
1.6
1.4
2.05
2.24
g/l
1.12
136
1007
6
7
8.62
3.26
1.2
1.4
—
—
—
0
0
14
49
2.89
3.20
1.7
1.5
—
—
—
0
0
7
11
6.40
3.19
3.1
1.6
—
—
—
0
0
25
117
2.17
3.18
1.8
1.6
—
—
—
0
0
19
79
2.44
3.15
1.7
1.9
—
—
—
0
0
734
6900
1.37
3.14
4.9
4.0
4.53
4.66
mmol/l
3.10
694
6462
77
513
1.55
3.14
1.4
1.2
184.68
225.95
u/ml
0.23
70
472
707
6610
1.34
3.12
4.4
3.6
1.42
1.26
mmol/l
3.59
665
6129
42
239
1.80
3.11
2.9
2.0
—
—
—
0
0
73
482
1.56
3.10
2.2
2.2
9.53
12.30
nmol/l
2.00
68
434
6
8
7.54
3.06
6.2
4.1
6.80
9.15
mmol/l
—
6
8
25
120
2.11
3.01
1.1
1.1
—
—
—
0
0
540
4884
1.27
3.00
4.2
3.1
46.61
42.77
u/l
0.51
519
4610
22
101
2.21
2.95
1.0
1.1
26.93
17.69
u/l
0.28
22
85
21
95
2.24
2.91
1.3
1.3
—
—
—
0
0
21
97
2.19
2.78
4.8
3.4
1.07
1.07
%
0.00
21
88
25
124
2.05
2.78
2.6
1.7
—
—
—
0
0
22
104
2.14
2.76
2.2
1.5
—
—
—
0
0
5
6
8.37
2.75
1.2
1.2
—
—
—
0
0
11
34
3.26
2.73
1.2
1.9
—
—
—
0
0
11
34
3.26
2.73
1.2
1.9
—
—
—
0
0
227
1868
1.29
2.70
1.3
1.3
2.99
1.85
u/ml
0.42
64
513
12
40
3.03
2.70
1.9
1.7
—
—
—
0
0
27
141
1.94
2.63
1.1
1.2
—
1.32
—
0
10
38
223
1.74
2.58
1.3
1.2
—
—
—
0
0
11
36
3.08
2.57
1.4
4.6
45.60
145.50
umol/l
—
5
22
844
8195
1.63
2.51
30.9
18.2
261.26
254.58
e9/l
2.28
826
7985
19
89
2.16
2.46
2.1
1.5
—
—
—
0
0
844
8200
1.62
2.44
30.8
18.2
4.49
4.51
e12/l
0.49
828
7978
25
131
1.93
2.42
2.2
1.7
—
—
—
0
0
25
131
1.93
2.42
2.2
1.7
—
—
—
0
0
844
8204
1.61
2.38
31.1
18.4
133.69
135.11
g/l
1.95
834
8089
18
84
2.17
2.36
1.2
1.6
—
—
—
0
0
27
147
1.86
2.35
1.1
1.2
—
—
—
0
0
27
147
1.86
2.35
1.2
1.1
—
12.82
—
0
12
843
8195
1.59
2.34
31.6
18.4
39.67
40.16
%
1.30
793
7732
37
223
1.69
2.31
1.3
1.2
—
—
—
0
0
19
92
2.09
2.28
1.1
1.2
—
—
—
0
0
20
99
2.04
2.27
4.5
4.2
79.29
328.27
u/ml
0.52
20
94
6
13
4.64
2.27
1.0
1.2
—
—
—
0
0
6
13
4.64
2.27
3.0
2.5
—
—
—
0
0
86
631
1.40
2.21
5.7
2.3
34.37
34.04
u/l
0.03
75
526
17
81
2.12
2.13
1.1
1.0
—
—
—
0
0
60
415
1.48
2.12
2.3
3.0
108.21
162.39
ng/l
1.35
52
375
20
102
1.98
2.11
1.2
1.6
—
—
—
0
0
5
10
5.02
2.07
1.0
1.3
—
—
—
0
0
19
96
2.00
2.06
1.9
1.6
—
—
—
0
0
19
96
2.00
2.06
1.9
1.6
—
—
—
0
0
52
353
1.50
2.02
5.8
2.7
0.13
0.15
e6/l
0.15
52
339
11
45
2.46
1.93
1.3
1.2
—
—
—
0
0
13
58
2.26
1.91
1.2
1.1
—
—
—
0
0
9
34
2.66
1.87
1.1
1.3
—
—
—
0
0
9
34
2.66
1.87
1.1
1.3
—
—
—
0
0
151
1240
1.26
1.81
1.3
1.3
16.16
31.73
iu/ml
2.71
35
391
22
123
1.81
1.81
2.3
1.4
—
—
—
0
0
30
184
1.65
1.80
1.5
1.4
263.60
321.54
ug/g
0.64
15
104
32
200
1.62
1.79
1.2
1.2
—
17.94
—
0
9
12
54
2.24
1.74
1.6
1.3
1.05
1.48
nmol/l
1.11
12
47
26
156
1.69
1.70
3.0
2.3
380.19
110.26
ug/min
0.57
18
91
198
1696
1.22
1.62
5.2
4.7
9.11
2.48
ug/l
0.64
176
1520
8
32
2.51
1.60
1.0
1.5
—
—
—
0
0
8
32
2.51
1.60
5.5
1.9
27.50
27.31
umol/l
—
8
32
53
722
0.72
1.56
1.5
1.6
—
—
—
0
0
8
33
2.44
1.54
1.0
1.3
13.50
12.52
u/l
—
8
33
74
567
1.33
1.52
4.5
4.3
131.02
34.50
ug/l
0.36
58
466
209
1811
1.20
1.51
1.8
1.7
1.35
1.37
mmol/l
0.20
178
1550
29
434
0.66
1.43
1.4
1.5
—
—
—
0
0
9
40
2.26
1.40
3.1
1.2
—
—
—
0
0
15
84
1.80
1.27
1.1
1.1
96.07
95.53
%
0.03
15
77
8
35
2.30
1.27
1.3
1.1
55.25
29.13
u/l
—
8
35
8
35
2.30
1.27
1.3
1.5
—
—
—
0
0
8
35
2.30
1.27
1.3
1.1
138.63
89.00
u/l
—
8
35
79
981
0.79
1.25
1.7
1.7
1.42
1.44
%
0.07
70
879
8
38
2.12
1.18
3.9
3.0
37575.00
37681.71
ug/l
—
8
38
27
392
0.68
1.18
1.2
1.4
—
—
—
0
0
158
1369
1.19
1.15
4.8
4.2
22.55
20.89
%
0.70
82
633
24
158
1.53
1.15
1.1
1.4
—
—
—
0
0
13
72
1.82
1.15
1.8
1.7
33.77
33.11
pg
0.49
13
72
17
103
1.66
1.13
1.3
1.1
—
—
—
0
0
10
51
1.97
1.11
1.1
1.5
0.88
0.99
g/l
—
10
51
58
736
0.77
1.11
1.4
1.5
—
—
—
0
0
7
31
2.27
1.10
1.0
1.5
—
—
—
0
0
28
394
0.70
1.06
1.3
1.4
—
—
—
0
0
28
394
0.70
1.06
1.3
1.4
—
—
—
0
0
28
393
0.70
1.04
1.3
1.4
—
—
—
0
0
94
790
1.21
0.97
5.0
4.1
30.48
31.50
%
0.47
75
548
0
31
0.00
0.96
0.0
1.2
—
12.10
—
0
31
0
32
0.00
0.95
0.0
1.3
—
—
—
0
0
19
125
1.53
0.94
1.2
1.1
—
—
—
0
0
22
150
1.48
0.93
2.1
3.9
20.89
25.66
mg/l
0.33
14
101
10
55
1.83
0.92
1.0
1.1
—
95.14
—
0
7
49
387
1.28
0.88
1.6
1.7
—
—
—
0
0
8
43
1.87
0.87
1.0
1.3
1.67
1.57
g/l
—
8
43
6
31
1.94
0.84
1.0
1.2
—
—
—
0
0
6
31
1.94
0.84
1.0
1.2
—
—
—
0
0
565
5423
1.12
0.84
3.3
3.5
—
—
—
0
0
23
313
0.73
0.76
1.6
1.8
—
—
—
0
0
132
1481
0.87
0.74
2.3
2.3
—
—
—
0
0
11
172
0.64
0.74
1.5
1.2
—
—
—
0
0
10
60
1.67
0.72
1.1
1.5
—
—
—
0
0
10
60
1.67
0.72
1.0
1.2
—
—
—
0
0
10
60
1.67
0.72
1.0
1.2
—
—
—
0
0
10
61
1.65
0.68
1.0
1.2
—
—
—
0
0
10
61
1.65
0.68
1.0
1.2
—
—
—
0
0
10
61
1.65
0.68
1.0
1.2
—
—
—
0
0
5
27
1.86
0.68
3.4
2.2
—
—
—
0
0
5
27
1.86
0.68
3.4
2.2
—
—
—
0
0
18
127
1.43
0.68
1.0
1.1
12.33
7.23
u/ml
—
10
62
5
28
1.79
0.66
3.4
2.2
—
—
—
0
0
58
487
1.20
0.65
1.4
1.4
—
—
—
0
0
10
63
1.59
0.62
2.9
2.3
—
—
—
0
0
28
218
1.29
0.60
1.6
1.7
36.29
41.99
nmol/l
0.85
28
209
8
51
1.57
0.60
1.3
1.3
65.50
71.69
umol/l
—
8
51
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
6
36
1.67
0.56
3.2
2.0
—
—
—
0
0
6
36
1.67
0.56
3.2
2.0
—
—
—
0
0
39
465
0.83
0.50
1.1
1.0
—
—
—
0
0
10
67
1.50
0.50
2.3
1.8
—
—
—
0
0
10
67
1.50
0.50
2.3
1.8
—
—
—
0
0
10
67
1.50
0.50
2.3
1.8
—
—
—
0
0
21
268
0.78
0.49
1.8
1.7
—
—
—
0
0
13
93
1.40
0.48
1.5
1.2
—
—
—
0
0
10
143
0.70
0.48
1.4
1.3
—
—
—
0
0
23
183
1.26
0.45
1.1
1.2
4.55
3.68
u/ml
0.16
12
102
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
4.2
2.3
—
—
—
0
0
156
1463
1.08
0.37
1.3
1.5
—
—
—
0
0
29
342
0.84
0.36
1.5
1.6
—
—
—
0
0
131
1222
1.08
0.35
1.3
1.2
3.35
12.09
u/ml
2.70
44
480
5
80
0.62
0.35
1.8
1.9
—
—
—
0
0
6
43
1.40
0.35
8.3
3.1
—
—
—
0
0
38
330
1.16
0.34
1.8
1.7
8.19
2.96
mg/l
0.64
31
239
6
45
1.34
0.34
1.0
1.4
158.58
188.27
pmol/l
—
6
45
127
1355
0.93
0.32
2.1
2.1
—
—
—
0
0
14
176
0.79
0.32
1.6
1.6
—
—
—
0
0
7
53
1.32
0.31
2.1
1.5
0.87
1.25
promille
—
7
40
35
306
1.15
0.30
1.6
1.4
—
—
—
0
0
26
222
1.18
0.29
2.8
3.3
91.35
1752.76
u/ml
1.30
20
196
39
345
1.14
0.29
1.4
1.3
51.10
255.38
miu/ml
12.97
13
171
27
312
0.86
0.28
1.8
1.7
—
—
—
0
0
19
158
1.21
0.28
1.1
1.1
1.50
1.61
u/ml
—
9
86
171
1794
0.94
0.28
1.9
1.6
—
—
—
0
0
24
205
1.18
0.27
2.2
1.7
2.33
6.17
iu/l
—
5
71
43
478
0.89
0.26
1.4
1.4
—
—
—
0
0
8
67
1.20
0.26
1.1
1.8
—
—
—
0
0
20
235
0.85
0.26
1.1
1.1
—
7.14
—
0
30
12
96
1.25
0.24
1.2
1.4
—
—
—
0
0
78
727
1.08
0.24
1.7
1.9
—
—
—
0
0
24
275
0.87
0.23
1.4
1.4
—
—
—
0
0
12
97
1.24
0.23
1.2
1.4
—
—
—
0
0
12
97
1.24
0.23
1.2
1.4
—
—
—
0
0
12
97
1.24
0.23
1.2
1.4
—
—
—
0
0
16
135
1.19
0.21
1.3
1.3
—
—
—
0
0
16
135
1.19
0.21
1.3
1.3
—
—
—
0
0
12
98
1.23
0.21
1.2
1.4
—
—
—
0
0
12
98
1.23
0.21
1.2
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
9
111
0.81
0.20
1.2
1.5
6.16
7.17
mmol/l
—
9
97
6
53
1.13
0.18
4.2
1.8
—
—
—
0
0
7
58
1.21
0.18
1.3
1.5
—
—
—
0
0
7
58
1.21
0.18
5.0
3.7
—
—
—
0
0
8
73
1.10
0.15
1.1
1.1
—
—
—
0
0
18
159
1.13
0.15
1.0
1.2
—
—
—
0
0
103
995
1.04
0.12
3.2
2.9
0.83
0.77
ug/l
0.36
70
637
93
903
1.03
0.09
1.8
2.0
—
—
—
0
0
6
55
1.09
0.09
1.8
1.4
—
—
—
0
0
17
156
1.09
0.08
1.1
1.3
—
—
—
0
0
7
68
1.03
0.08
2.3
1.6
—
—
—
0
0
7
84
0.83
0.07
1.3
1.5
—
—
—
0
0
18
193
0.93
0.06
1.7
1.4
170.06
122.81
pmol/l
0.15
18
188
15
143
1.05
0.01
1.4
1.7
—
—
—
0
0
11
116
0.95
0.00
3.8
5.4
376.36
378.21
umol/l
0.02
11
102
28
284
0.99
0.00
1.5
1.5
—
—
—
0
0
27
268
1.01
0.00
1.4
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
69
0.87
-0.00
1.5
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
53
0.94
-0.00
1.6
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
2.93
—
0
7
0
9
0.00
-0.00
0.0
3.2
—
71.41
—
0
9
6
65
0.92
-0.00
1.2
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_PAPILLOEDEMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PAPILLOEDEMA | 1.805 [1.5, 2.18] | < 0.001 |
| Birth year | 1.0 [0.99, 1.01] | 0.933 |
During the follow-up period (1.1.1998 — 31.12.2019), 302 out of 2534 females with H7_PAPILLOEDEMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PAPILLOEDEMA | 1.735 [1.45, 2.08] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.026 |
During the follow-up period (1.1.1998 — 31.12.2019), 318 out of 1743 males with H7_PAPILLOEDEMA died.
Mortality risk
Mortality risk for people of age
years, who have H7_PAPILLOEDEMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.222% | 0.329% |
| 5 | 1.191% | 2.395% |
| 10 | 2.856% | 5.595% |
| 15 | 5.566% | 10.492% |
| 20 | 10.02% | 17.3% |
Relationships between endpoints
↥Index endpoint: H7_PAPILLOEDEMA – Papilloedema, unspecified
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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