Disorder of visual pathways, unspecified

H7_VISUALPATHNAS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H47.7 Hospital discharge: ICD-9 — 3779 Cause of death: ICD-10 — H47.7 Cause of death: ICD-9 — 3779 2 out of 7 registries used, show all original rules.	63
4. Check minimum number of events None	63
5. Include endpoints None	63
6. Filter based on genotype QC (FinnGen only)	63

Control definitions (FinnGen only)

Control exclude: H7_OPTNERVE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H47
Name in latin: Morbositas partis non specificatae tractuum opticorum

NAME	H7_VISUALPATHNAS
CONTROL_EXCLUDE	H7_OPTNERVE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H477
HD_ICD_9	3779
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H477
COD_ICD_9	3779
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Disorder of visual pathways, unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	537	259	275
Only index persons	443	214	229
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	18.91	22.93	14.70
Only index persons	24.82	34.55	15.73

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	63	33	30
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	46.06	48.85	43.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
57: Matched controls
568

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H47.7

ICD-10 Finland

Disorder of visual pathways, unspecified

+∞

76.5

R5110

NOMESCO Finland

Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it

11.8

13.4

H47.2

ICD-10 Finland

Optic atrophy

+∞

10.7

F79.0

ICD-10 Finland

Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour

32.9

10.3

Z50.8

ICD-10 Finland

Care involving use of other rehabilitation procedures

11.4

9.5

RT274

NOMESCO Finland

59.5

9.0

H54.7

ICD-10 Finland

Unspecified visual loss

104.9

8.7

H47.0

ICD-10 Finland

Disorders of optic nerve, not elsewhere classified

+∞

8.5

M03BX01

ATC

baclofen; systemic

+∞

8.5

181

Kela drug reimbursment

Retigabine and vigabatrin

+∞

8.5

XCK00

NOMESCO Finland

Perimetry

12.3

8.4

504

Kela drug reimbursment

Conditions requiring daily forced enteral nutrition

29.7

7.9

R2130

NOMESCO Finland

Counselling and guidance which enhance independent living

6.5

7.8

RL140

NOMESCO Finland

19.0

7.6

H51.9

ICD-10 Finland

Disorder of binocular movement, unspecified

+∞

7.4

N03AG04

ATC

vigabatrin; oral

+∞

7.4

G80.9

ICD-10 Finland

Cerebral palsy, unspecified

+∞

7.4

N05BA09

ATC

clobazam; oral

34.9

7.4

RT160

NOMESCO Finland

34.9

7.4

XCD10

NOMESCO Finland

Electrophysiological examination of eye

34.9

7.4

ZX114

NOMESCO Finland

Intramuscular

45.6

6.9

RS142

NOMESCO Finland

78.3

6.6

TJD20

NOMESCO Finland

Change of gastrostomy tube

78.3

6.6

G80.8

ICD-10 Finland

Other cerebral palsy

+∞

6.4

JDB10

NOMESCO Finland

Percutaneous gastrostomy

+∞

6.4

Z01.0

ICD-10 Finland

Examination of eyes and vision

4.9

6.3

182

Kela drug reimbursment

Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide

17.4

6.1

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007853) Bacteria identified in Skin by Aerobe culture

4.27

6.29

1.4

1.5

—

(36304419) Bacteria [Presence] in Urine

165

3.10

4.65

2.8

3.9

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

201

3.04

4.45

2.8

4.2

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.02

3.90

17.1

12.7

24.5

25.1

mmol/l

0.21

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

287

2.99

3.82

12.4

9.3

1.2

mmol/l

0.31

249

(3016018) Differential panel - Cerebral spinal fluid

10.87

3.57

4.0

3.7

—

(3030467) Casts [#/volume] in Urine by Automated count

168

2.66

3.54

3.0

4.1

0.8

0.3

e6/l

0.39

131

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

4.21

3.51

2.4

1.6

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

328

2.95

3.39

8.3

6.0

6.7

6.5

mmol/l

0.16

310

(3018095) Leukocytes [#/volume] in Urine

214

2.59

3.36

3.5

4.8

235.3

66.4

e6/l

0.63

155

(3023368) Bacteria identified in Blood by Culture

126

2.63

3.25

4.2

—

(3022313) Gas panel - Capillary blood

2.87

3.18

10.7

8.0

—

(3012544) pH of Venous blood

105

2.68

3.17

3.9

10.6

—

(3026008) Bacteria identified in Urine by Culture

146

2.49

3.00

3.9

2.9

—

(3000991) Gas panel - Venous blood

2.59

2.74

12.5

13.4

—

(3002582) Erythrocytes [#/volume] in Urine

189

2.26

2.54

3.0

4.0

140.8

371.1

e6/l

0.29

149

(3002385) Erythrocyte distribution width [Ratio]

466

3.34

2.51

21.7

18.1

14.0

13.5

1.19

457

(3009343) pH of Capillary blood

2.43

11.3

7.3

—

7.4

—

(3023410) Appearance of Cerebral spinal fluid

6.67

2.41

5.0

4.6

—

(3013005) Retinol [Moles/volume] in Serum or Plasma

6.67

2.41

1.6

4.4

1.7

umol/l

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

105

2.33

2.29

2.7

3.8

1.4

0.6

e6/l

0.78

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

5.92

2.25

1.0

2.0

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

3.37

2.09

12.6

15.0

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

4.30

2.09

1.3

3.4

2317.8

314.7

mg/l

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

150

2.11

2.05

2.8

2.0

360.4

240.7

u/l

0.32

143

(3042936) Bacteria identified in Isolate by Culture

2.36

1.87

1.6

1.8

—

(3015736) pH of Urine

198

1.98

1.87

5.5

3.7

—

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

4.42

1.86

1.4

3.7

3.5

3.7

mmol/l

—

(3021601) Nitrite [Presence] in Urine by Test strip

246

1.95

1.80

7.1

5.8

0.0

estimate

—

(3035350) Ketones [Presence] in Urine by Test strip

246

1.95

1.80

5.9

3.9

0.0

estimate

—

(3044290) Cell count panel - Cerebral spinal fluid

4.08

1.75

5.0

3.6

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

4.08

1.75

1.0

1.5

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

4.08

1.75

1.0

1.5

—

(3009261) Glucose [Presence] in Urine by Test strip

248

1.93

1.74

6.1

4.0

0.0

estimate

—

(40761535) Cells panel - Urine sediment

2.80

1.73

4.0

3.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

351

1.99

1.63

5.7

4.6

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

161

1.92

1.63

1.6

2.2

98.7

96.9

pmol/l

0.06

(3000330) Specific gravity of Urine by Test strip

2.79

1.56

6.0

4.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

123

1.92

1.47

6.0

3.7

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.90

1.47

1.0

1.1

—

(3019060) Gas panel - Arterial blood

2.65

1.34

3.3

3.2

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

104

1.87

1.26

2.8

3.8

1.8

1.6

e6/l

—

(3006315) Basophils [#/volume] in Blood

297

1.70

1.20

4.5

8.3

0.0

e9/l

0.11

254

(3001604) Monocytes [#/volume] in Blood

298

1.69

1.18

4.5

8.2

0.6

e9/l

0.75

255

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

242

1.66

1.13

4.3

3.7

—

(3044640) Blood type and Crossmatch panel - Blood

187

1.66

1.10

2.2

2.5

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.05

1.08

1.8

—

(3026493) Urate [Moles/volume] in Serum or Plasma

130

0.48

1.02

2.4

3.2

308.3

7307.5

umol/l

—

108

(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum

0.00

1.00

0.0

1.7

—

243.0

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

528

2.24

1.00

24.3

16.5

4.0

mmol/l

0.13

516

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

1.00

0.0

1.6

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

1.00

0.0

1.8

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.89

0.99

1.8

1.7

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

175

1.60

0.94

5.5

4.0

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

2.18

0.92

2.8

5.1

30.2

26.6

nmol/l

—

(3017446) Testosterone [Moles/volume] in Serum or Plasma

1.98

0.91

2.8

1.8

11.5

11.4

nmol/l

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

2.10

0.89

1.3

1.2

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

534

2.08

0.87

10.1

11.1

28.2

25.0

u/l

0.56

523

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.96

0.84

2.5

2.2

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.81

0.0

2.3

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.81

0.0

1.5

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.00

0.80

0.0

1.5

—

(3029937) Albumin [Presence] in Urine by Test strip

118

1.60

0.80

5.1

3.6

0.0

estimate

—

(3052851) Hemolysis interference index of Serum or Plasma

2.27

0.78

4.4

2.3

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

512

1.84

0.77

19.4

14.5

35.9

22.4

mg/l

1.58

392

(3005719) IgG [Mass/volume] in Serum or Plasma

1.71

0.76

2.7

3.4

8.5

9.3

g/l

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.17

0.76

1.6

2.1

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.92

0.70

2.2

1.6

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

158

1.49

0.69

3.0

3.7

22.2

48.0

ng/l

0.99

106

(40760892) CBC W Ordered Manual Differential panel - Blood

106

1.54

0.65

3.1

5.8

—

(3000494) Fungus identified in Specimen by Culture

1.65

0.63

1.5

1.6

—

(3008898) HLA-B27 [Presence]

0.00

0.61

0.0

1.0

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

0.61

0.0

1.1

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.59

0.0

2.3

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

1.69

0.57

2.7

2.1

—

(3009542) Hematocrit [Volume Fraction] of Blood

477

1.52

0.54

23.0

17.7

38.8

39.1

0.11

372

(3021589) Normoblasts [#/volume] in Blood

291

1.37

0.53

6.3

10.7

0.0

e9/l

0.50

227

(42870588) Differential panel, method unspecified - Blood

233

1.36

0.52

4.1

7.9

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.62

0.51

18.1

7.8

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.59

0.49

2.2

1.7

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.50

0.47

2.5

1.7

—

(40768804) Tissue Pathology biopsy report

169

0.71

0.44

3.1

2.1

—

(3022621) pH of Urine by Test strip

1.66

0.44

2.6

2.7

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

143

1.36

0.43

2.1

2.5

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

0.41

0.0

1.5

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.41

0.0

1.9

—

339.3

—

(3007566) Smooth muscle Ab [Titer] in Serum

0.00

0.41

0.0

1.5

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

117

1.37

0.40

5.3

9.9

1.1

1.2

mmol/l

1.31

110

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

142

0.73

0.35

2.9

1.8

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

375

1.27

0.33

14.7

13.1

84.4

82.5

ml/min/173m2

0.16

303

(3041096) Erythrocytes [Presence] in Urine by Automated

130

1.31

0.33

4.5

3.6

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.68

0.28

1.4

1.5

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.29

0.27

2.4

370.0

372.8

nmol/l

—

(3007164) IgA [Mass/volume] in Serum or Plasma

172

1.24

0.26

1.6

1.7

2.4

2.0

g/l

0.46

(3013707) Erythrocyte sedimentation rate by Westergren method

380

1.23

0.26

3.9

4.7

10.5

10.4

mm/h

0.02

352

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

437

0.82

0.24

4.8

4.2

6.2

5.9

mmol/l

0.72

404

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

388

0.83

0.24

4.0

3.3

—

(3013512) EKG study

134

0.78

0.23

3.5

4.2

—

(3022145) Colonoscopy Study observation

1.27

0.23

1.0

1.4

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.0

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

3.3

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.0

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

2.5

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

5.5

—

0.8

—

(3010375) cycloSPORINE [Mass/volume] in Blood

0.00

0.21

0.0

51.1

—

159.9

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.8

—

0.0

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.2

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.21

0.0

1.2

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.21

0.0

1.0

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.7

—

10.9

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.3

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

1.6

—

(4035726)

1.25

0.21

1.2

1.7

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.79

0.16

1.4

2.0

—

(40758558) Short blood count panel - Blood

173

1.14

0.12

3.9

8.8

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

1.15

0.10

1.4

1.2

—

151.0

—

(4010399)

1.09

0.10

1.2

1.4

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

415

1.11

0.09

3.5

4.0

14.6

14.7

pmol/l

0.12

381

(36660697) Celiac disease serology panel - Serum

0.86

0.07

1.3

1.4

—

(3048689) Calprotectin [Mass/mass] in Stool

0.84

0.07

1.6

2.2

1023.0

97.8

ug/g

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

0.81

0.07

2.0

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

311

0.93

0.05

3.8

4.3

52.2

48.0

u/l

0.13

297

(1761868) Lipid panel - Serum or Plasma

140

1.09

0.05

4.2

2.9

—

(3003694) ABO and Rh group [Type] in Blood

137

0.94

0.02

1.7

1.5

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

114

1.07

0.01

3.0

1.3

0.9

mg/l

0.35

(3009508) Creatinine [Moles/volume] in Urine

157

1.03

0.00

2.2

4.6

7.6

7.5

mmol/l

0.03

138

(3044889) 12 lead EKG panel

332

0.99

0.00

4.3

3.5

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

0.0

5.8

—

20.3

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.2

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.0

1.2

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

0.0

3.2

—

300.3

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.5

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.8

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.5

—

104.3

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.5

—

(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma

0.00

0.0

1.5

—

(40768441) Liver Pathology biopsy report

0.00

0.0

2.5

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.2

—

(3003752) BK virus DNA [Units/volume] (viral load) in Urine by NAA with probe detection

0.00

0.0

5.8

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.2

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

2.8

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.2

—

(3032390) JC virus DNA [#/volume] (viral load) in Urine by NAA with probe detection

0.00

0.0

5.8

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3002621) Streptococcal DNAse B [Units/volume] in Serum

0.00

0.0

1.5

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.6

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.0

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40768797) Stomach Pathology biopsy report

0.93

0.00

1.5

1.4

—

(3022217) INR in Platelet poor plasma by Coagulation assay

1.00

0.00

8.0

35.1

—

1.5

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(4146454)

0.00

0.0

3.0

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.9

—

0.0

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.0

1.5

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.3

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.0

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.92

0.00

1.2

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.9

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

0.8

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.9

—

0.0

—

(3012494) Peanut IgE Ab [Units/volume] in Serum

0.00

0.0

1.0

—

92.1

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

0.0

1.0

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.90

0.00

1.4

1.2

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

4.0

—

5.8

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.9

—

0.0

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

0.0

1.0

—

89.7

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

3.0

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.0

5.6

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

0.0

2.0

—

28.5

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.1

—

(4268621)

0.00

0.0

1.8

—

(3029493) Herpes virus 6 DNA [Presence] in Blood by NAA with probe detection

0.00

0.0

8.0

—

(3022756) Ceruloplasmin [Mass/volume] in Serum or Plasma

0.00

0.0

1.2

—

286.2

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.8

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.0

1.5

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.8

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

1.9

—

35.2

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.1

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.4

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

5.8

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.0

—

(4094501)

0.00

0.0

1.3

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.0

1.2

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

4.1

—

155.3

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.0

5.6

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

159.5

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3000504) BK virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

8.2

—

(40768446) Kidney Pathology biopsy report

0.00

0.0

1.9

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.0

—

(3042733) HLA Ab [Presence] in Serum

0.00

0.0

2.8

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.0

1.3

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.1

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

96.6

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.8

—

(3022229) Phosphate [Moles/volume] in Urine

0.00

0.0

3.3

—

18.0

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_VISUALPATHNAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_VISUALPATHNAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H7_VISUALPATHNAS – Disorder of visual pathways, unspecified

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Disorder of visual pathways, unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints