No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
63 |
4. Check minimum number of eventsNone |
63 |
5. Include endpointsNone |
63 |
6. Filter based on genotype QC (FinnGen only) |
63 |
Control definitions (FinnGen only)
- Control exclude
- H7_OPTNERVE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H47
- Name in latin
- Morbositas partis non specificatae tractuum opticorum
Similar endpoints
↥List of similar endpoints to
Disorder of visual pathways, unspecified
based on the number of shared cases.
Similar with more cases:
- Other disorders of optic [2nd] nerve and visual pathways
- Disorders of optic nerve and visual pathways
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 537 | 259 | 275 |
| Only index persons | 443 | 214 | 229 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 18.91 | 22.93 | 14.70 |
| Only index persons | 24.82 | 34.55 | 15.73 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 63 | 33 | 30 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 46.06 | 48.85 | 43.00 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 57
- Matched controls
- 568
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
76.5
55
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
11.8
13.4
27
40
Z3229
NOMESCO Finland
Other healthcare associate professional
10.3
11.7
25
40
H47.2
ICD-10 Finland
Optic atrophy
+∞
10.7
10
*
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
32.9
10.3
13
5
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
11.4
9.5
18
22
RT274
NOMESCO Finland
NA
59.5
9.0
10
*
H54.7
ICD-10 Finland
Unspecified visual loss
104.9
8.7
9
*
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
+∞
8.5
8
*
181
Kela drug reimbursment
Retigabine and vigabatrin
+∞
8.5
8
*
M03BX01
ATC
baclofen; systemic
+∞
8.5
8
*
XCK00
NOMESCO Finland
Perimetry
12.3
8.4
15
16
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
29.7
7.9
10
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.5
7.8
22
50
RL140
NOMESCO Finland
NA
19.0
7.6
11
7
N03AG04
ATC
vigabatrin; oral
+∞
7.4
7
*
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
+∞
7.4
7
*
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
+∞
7.4
7
*
N05BA09
ATC
clobazam; oral
34.9
7.4
9
*
RT160
NOMESCO Finland
NA
34.9
7.4
9
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
34.9
7.4
9
*
ZX114
NOMESCO Finland
Intramuscular
45.6
6.9
8
*
RS142
NOMESCO Finland
NA
78.3
6.6
7
*
TJD20
NOMESCO Finland
Change of gastrostomy tube
78.3
6.6
7
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
+∞
6.4
6
*
G80.8
ICD-10 Finland
Other cerebral palsy
+∞
6.4
6
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.9
6.3
23
69
Z2446
NOMESCO Finland
Social worker
5.4
6.3
20
52
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
17.4
6.1
9
6
Mortality – FinRegistry
↥Association
Association between endpoint H7_VISUALPATHNAS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have H7_VISUALPATHNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: H7_VISUALPATHNAS – Disorder of visual pathways, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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