No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
183 |
4. Check minimum number of eventsNone |
183 |
5. Include endpointsNone |
183 |
6. Filter based on genotype QC (FinnGen only) |
175 |
Control definitions (FinnGen only)
- Control exclude
- AB1_INTESTINAL_INFECTIONS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Typhoid and paratyphoid fevers
based on the number of shared cases.
Similar with more cases:
- Typhoid and paratyphoid fevers
- Intestinal infectious diseases
- Intestinal infectious diseases
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1560 | 772 | 765 |
| Only index persons | 1249 | 640 | 609 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.02 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 34.76 | 36.42 | 32.62 |
| Only index persons | 29.08 | 30.04 | 28.08 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 175 | 103 | 72 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.03 |
| Median age at first event (years) | 39.25 | 38.24 | 40.70 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 183
- Matched controls
- 1830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
00210
ICD-8 Finland
Paratyphoid fever B
+∞
30.0
28
*
A01.0
ICD-10 Finland
Typhoid fever
+∞
27.8
26
*
A01.4
ICD-10 Finland
Paratyphoid fever, unspecified
+∞
14.8
14
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.6
14.2
39
102
I39.8*A01.0
ICD-10 Finland
Endocarditis in typhoid fever
+∞
11.6
11
*
M01.3*A01.4
ICD-10 Finland
Arthritis in typhoid or paratyphoid fever
+∞
11.6
11
*
00299
ICD-8 Finland
Paratyphoid fever unspecified
+∞
11.6
11
*
A01
ICD-10 Finland
Typhoid and paratyphoid fevers
+∞
10.5
10
*
00199
ICD-8 Finland
Typhoid fever, Unspecified
+∞
9.5
9
*
A01.1
ICD-10 Finland
Paratyphoid fever A
+∞
8.4
8
*
R50.9
ICD-10 Finland
Fever, unspecified
3.1
7.9
39
149
00220
ICD-8 Finland
Paratyphoid fever C
+∞
7.3
7
*
0029X
ICD-9 Finland
Typhoid and paratyphoid fevers, Paratyphoid fever, unspecified
+∞
7.3
7
*
0020A
ICD-9 Finland
Typhoid and paratyphoid fevers, Typhoid fever
+∞
7.3
7
*
0022A
ICD-9 Finland
Typhoid and paratyphoid fevers, Paratyphoid fever B
+∞
7.3
7
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
12
26
4.86
4.14
1.2
1.2
—
—
—
0
0
83
565
1.86
4.04
2.1
1.8
94.40
97.55
pmol/l
0.22
46
299
21
88
2.57
3.54
1.8
1.4
—
—
—
0
0
15
55
2.88
3.24
3.2
2.2
—
—
—
0
0
10
26
4.01
3.03
1.2
1.4
—
—
—
0
0
11
34
3.38
2.78
1.3
1.1
—
—
—
0
0
92
702
1.62
2.66
9.2
5.4
1.21
1.21
mmol/l
0.28
86
588
81
600
1.63
2.64
2.6
2.2
83.09
76.26
nmol/l
1.05
73
543
49
326
1.69
2.39
1.3
1.2
0.51
1.03
u/ml
—
9
88
8
23
3.59
2.30
1.0
1.3
—
—
—
0
0
27
155
1.87
2.15
11.4
6.3
11.72
12.36
kpa
0.29
27
150
27
155
1.87
2.15
11.4
6.3
5.00
5.14
kpa
0.38
27
150
18
90
2.11
2.09
6.9
5.7
25.33
24.52
mmol/l
0.36
18
85
96
769
1.52
2.08
5.7
5.5
9.72
11.21
umol/l
1.90
91
728
103
841
1.51
2.02
11.9
9.3
3.94
3.98
e9/l
0.08
96
738
103
842
1.51
2.00
6.9
4.0
6.60
6.64
mmol/l
0.08
93
775
33
211
1.69
1.85
1.8
1.9
—
—
—
0
0
15
75
2.09
1.75
1.0
1.1
—
—
—
0
0
131
1144
1.51
1.72
8.6
6.6
78.38
77.66
u/l
0.07
124
1067
88
715
1.44
1.66
3.8
3.7
0.00
0.00
estimate
-0.00
15
137
82
661
1.44
1.60
4.2
2.4
—
—
—
0
0
15
79
1.98
1.54
1.6
1.3
—
—
—
0
0
25
156
1.70
1.53
1.8
1.7
—
—
—
0
0
79
639
1.42
1.49
8.1
4.9
1.20
1.21
mmol/l
0.81
74
587
24
153
1.65
1.37
1.9
1.6
—
—
—
0
0
26
170
1.62
1.35
10.7
5.8
105.23
103.77
mmol/l
1.13
26
170
70
563
1.39
1.34
3.8
3.9
—
—
—
0
0
5
18
2.83
1.29
1.8
1.6
—
—
—
0
0
87
729
1.37
1.29
3.9
3.7
0.00
0.00
estimate
-0.00
13
126
128
1142
1.40
1.28
4.1
3.9
14.80
14.66
pmol/l
0.24
122
1033
38
276
1.48
1.25
4.2
3.6
2568.40
261.29
ng/l
0.43
25
214
5
19
2.68
1.22
7.8
4.5
—
—
—
0
0
27
183
1.56
1.22
2.4
2.3
22.00
23.52
%
0.19
21
158
155
1439
1.50
1.17
4.9
4.4
6.06
5.91
mmol/l
0.53
148
1327
85
720
1.34
1.14
6.0
4.9
0.00
0.00
estimate
-0.00
13
128
74
622
1.32
1.02
3.0
2.6
175.49
116.51
ug/l
0.36
67
580
42
326
1.37
0.97
2.3
2.0
2.68
3.21
mg/l
0.61
37
278
13
78
1.72
0.94
2.3
3.0
0.28
0.14
e6/l
0.44
13
72
6
29
2.10
0.90
1.7
1.1
1.09
0.88
nmol/l
—
6
24
40
313
1.36
0.88
2.6
2.2
—
—
—
0
0
8
44
1.85
0.87
1.5
1.1
—
—
—
0
0
8
44
1.85
0.87
1.5
1.1
—
—
—
0
0
64
539
1.29
0.85
4.2
3.4
25.02
37.44
ng/l
0.52
45
353
11
65
1.74
0.84
6.0
2.7
25.25
24.52
mmol/l
0.40
11
65
78
675
1.27
0.83
12.7
14.3
1.21
1.25
inr
0.12
23
188
49
399
1.31
0.83
3.3
3.5
3.19
7.70
mg/mmol
1.69
26
255
0
24
0.00
0.80
0.0
1.6
—
—
—
0
0
41
328
1.32
0.79
2.1
1.6
0.99
1.10
mg/l
0.12
30
262
5
24
2.11
0.75
1.0
1.4
—
—
—
0
0
5
24
2.11
0.75
1.0
1.4
—
—
—
0
0
12
76
1.62
0.73
1.8
1.3
—
—
—
0
0
7
40
1.78
0.72
2.9
1.3
—
—
—
0
0
6
37
1.64
0.56
1.7
1.5
—
—
—
0
0
10
66
1.54
0.53
21.5
9.3
25.08
24.59
mmol/l
—
10
66
6
39
1.56
0.53
1.5
1.4
—
—
—
0
0
11
75
1.50
0.52
1.5
2.1
—
—
—
0
0
11
155
0.69
0.51
1.6
1.7
—
—
—
0
0
148
1415
1.24
0.50
14.2
12.1
83.25
82.51
ml/min/173m2
0.16
118
1159
7
45
1.58
0.49
1.7
2.0
—
—
—
0
0
52
454
1.20
0.49
3.2
2.3
52.96
55.75
u/l
0.26
47
416
7
47
1.51
0.48
1.9
2.4
—
—
—
0
0
143
1366
1.21
0.47
5.2
4.6
1.94
1.89
mu/l
0.24
137
1249
69
623
1.17
0.44
5.6
3.7
35.16
36.04
g/l
0.56
64
588
30
251
1.23
0.42
1.4
1.8
925.70
1229.99
nmol/l
1.16
23
190
27
224
1.24
0.41
3.3
2.8
4.83
3.69
e6/l
0.13
16
115
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
489.71
—
0
7
0
15
0.00
0.41
0.0
1.0
—
36.86
—
0
7
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
11.42
—
0
16
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
10
71
1.43
0.40
1.7
1.8
—
—
—
0
0
5
35
1.44
0.39
1.0
1.6
—
—
—
0
0
31
263
1.22
0.39
1.6
1.3
71.20
26.40
iu/ml
—
6
94
9
66
1.38
0.39
1.2
2.1
—
—
—
0
0
5
36
1.40
0.38
1.0
1.6
—
—
—
0
0
117
1110
1.15
0.37
5.3
3.7
13.90
10.82
mm/h
1.26
110
1019
6
46
1.31
0.33
3.5
2.6
—
—
—
0
0
30
259
1.19
0.32
1.6
1.3
11.74
15.65
u/ml
0.14
12
96
12
95
1.28
0.27
2.6
3.0
4.47
4.43
pmol/l
0.07
12
82
14
170
0.81
0.26
1.4
2.2
—
—
—
0
0
153
1493
1.15
0.25
19.7
12.6
24.68
22.30
mg/l
0.35
126
1148
5
37
1.36
0.23
1.2
1.4
—
—
—
0
0
144
1402
1.13
0.23
4.0
3.9
1.48
1.30
mmol/l
1.39
134
1291
5
41
1.23
0.22
1.2
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
2.3
—
13.58
—
0
12
91
950
0.92
0.20
3.5
3.1
—
—
—
0
0
142
1385
1.11
0.20
5.9
5.2
39.49
39.68
mmol/mol
0.09
137
1299
161
1581
1.15
0.20
20.8
14.8
78.89
76.06
umol/l
0.29
161
1581
14
165
0.84
0.20
8.7
6.9
—
—
—
0
0
42
390
1.10
0.17
3.0
2.8
0.04
0.52
e6/l
3.09
33
282
45
422
1.09
0.15
4.0
4.5
1.83
2.48
ug/l
0.76
40
374
26
238
1.11
0.14
3.0
2.5
1.09
1.16
e6/l
0.05
15
129
14
156
0.89
0.10
1.5
2.0
—
—
—
0
0
5
44
1.14
0.10
1.0
1.3
—
—
—
0
0
5
45
1.11
0.10
1.0
2.2
—
3447.49
—
0
17
51
492
1.05
0.07
3.1
2.9
2.36
2.35
mmol/l
0.24
46
440
53
512
1.05
0.07
2.9
2.9
—
—
—
0
0
144
1455
0.95
0.06
4.5
4.2
1.47
1.48
mmol/l
0.06
135
1347
24
227
1.07
0.06
1.4
1.5
—
—
—
0
0
27
282
0.95
0.05
1.7
1.6
—
—
—
0
0
102
1033
0.97
0.04
3.5
2.8
51.84
45.36
u/l
0.42
92
962
26
250
1.05
0.03
2.5
2.7
0.54
0.87
ug/l
1.42
15
143
31
320
0.96
0.03
1.4
1.8
427.84
18450642.64
pmol/l
0.50
25
271
167
1663
1.05
0.01
28.3
19.1
39.75
40.55
%
0.80
157
1571
14
139
1.01
0.00
2.9
3.3
—
—
—
0
0
34
336
1.01
0.00
3.9
4.1
22.32
21.84
%
0.04
14
146
130
1297
1.01
0.00
24.5
15.8
14.60
14.92
%
0.28
130
1280
147
1465
1.02
0.00
4.6
4.3
4.70
4.73
mmol/l
0.13
138
1362
40
398
1.01
0.00
3.8
4.1
0.00
0.01
estimate
0.50
14
125
149
1490
1.00
-0.00
5.5
4.8
2.71
2.81
mmol/l
0.63
139
1382
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
52.40
—
0
5
0
9
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.1
—
251.71
—
0
7
Mortality – FinRegistry
↥Association
Association between endpoint AB1_TYPHOIDPARATHYPHOID and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have AB1_TYPHOIDPARATHYPHOID.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: AB1_TYPHOIDPARATHYPHOID – Typhoid and paratyphoid fevers
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data