No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
5461 |
4. Check minimum number of eventsNone |
5461 |
5. Include endpointsNone |
5461 |
6. Filter based on genotype QC (FinnGen only) |
5461 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 5
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H35
Similar endpoints
↥List of similar endpoints to
Macular pucker
based on the number of shared cases.
Similar with more cases:
- Degeneration of macula and posterior pole
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 27005 | 13935 | 13051 |
| Only index persons | 26829 | 13856 | 12973 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.38 | 0.40 | 0.36 |
| Only index persons | 0.50 | 0.51 | 0.50 |
| Median age at first event (years) | |||
| Whole population | 71.79 | 71.14 | 72.47 |
| Only index persons | 71.79 | 71.14 | 72.48 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 5461 | 2696 | 2765 |
| Unadjusted period prevalence (%) | 1.07 | 0.92 | 1.22 |
| Median age at first event (years) | 71.49 | 70.05 | 72.89 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 4747
- Matched controls
- 47468
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H33.0
ICD-10 Finland
Retinal detachment with retinal break
790.7
323.0
366
5
Z96.1
ICD-10 Finland
Presence of intraocular lens
8.0
323.0
1847
3482
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
41.7
323.0
528
142
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
134.8
323.0
373
30
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
232.5
323.0
644
32
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
20.7
323.0
1844
1409
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
3493.0
323.0
895
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
4503599627370496.0
323.0
4741
54
CKC12
NOMESCO Finland
Photocoagulation of retina
104.4
323.0
504
54
H25.1
ICD-10 Finland
Senile nuclear cataract
4.0
323.0
2421
9728
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
421.7
323.0
661
18
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
210.0
323.0
684
38
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
578.5
323.0
860
18
H26.4
ICD-10 Finland
After-cataract
6.2
323.0
1167
2366
CJB10
NOMESCO Finland
Laser discission of secondary cataract
6.1
323.0
1032
2059
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
713.4
323.0
394
6
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
11.1
323.0
895
975
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
4.8
323.0
2914
11828
XCW99
NOMESCO Finland
Other investigative procedure of eye
12.6
323.0
1785
2169
WX140
NOMESCO Finland
Parabulbar anesthesy
55.2
323.0
1627
444
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
122.0
323.0
698
67
H35.37
ICD-10 Finland
Macular holes
971.6
323.0
360
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
4.6
323.0
2863
11862
H33.3
ICD-10 Finland
Retinal breaks without detachment
483.8
321.8
318
7
XCK10
NOMESCO Finland
Photography of fundus of eye
5.0
265.7
972
2338
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.8
249.0
1290
4288
CKD40
NOMESCO Finland
Endophotocoagulation of retina
181.7
247.8
258
15
H35.36
ICD-10 Finland
Macular cyst
+∞
237.5
226
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
315.2
236.0
238
8
ZXA10
NOMESCO Finland
Bilateral
3.3
230.3
1484
5793
WX002
NOMESCO Finland
Sedation and analgesia
3.1
223.6
1590
6631
WX100
NOMESCO Finland
Conjunctival surface anesthesia
3.1
154.7
1013
3838
H34.8
ICD-10 Finland
Other retinal vascular occlusions
165.4
152.4
160
10
ZXA05
NOMESCO Finland
Left side
2.4
149.2
1699
8902
ZXA00
NOMESCO Finland
Right side
2.4
149.0
1801
9728
H3601, E113
ICD-10 Finland
NA
+∞
146.6
140
*
S01ED51
ATC
timolol, combinations; ophthalmic
3.9
145.3
666
1906
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
144.6
2402
15021
XCD20
NOMESCO Finland
Photoangiography of eye
56.4
142.0
169
31
XCH00
NOMESCO Finland
Eye pressure measurement
5.8
141.3
427
792
H3600, E113
ICD-10 Finland
NA
+∞
114.0
109
*
H25.0
ICD-10 Finland
Senile incipient cataract
3.6
105.0
530
1620
H43.1
ICD-10 Finland
Vitreous haemorrhage
10.5
102.6
207
206
CKC10
NOMESCO Finland
Local photocoagulation of retina
58.5
101.6
120
21
H36.01
ICD-10 Finland
Diabetic maculopathy
195.8
92.6
96
5
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
90.9
87
*
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
234.4
89.8
92
*
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.8
88.5
627
2422
WX142
NOMESCO Finland
Sub-tenon anesthesy
33.9
88.4
116
35
A98
ICPC
Health maint/preventive medicine
3.4
85.0
4548
41349
XCK00
NOMESCO Finland
Perimetry
3.2
84.5
499
1702
H3603, E113
ICD-10 Finland
NA
+∞
81.5
78
*
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
275.5
79.8
81
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
12.5
73.0
134
110
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
187.8
71.3
74
*
114
Kela drug reimbursment
Glaucoma
2.5
67.7
601
2619
H40.0
ICD-10 Finland
Glaucoma suspect
2.7
67.5
512
2040
H36.00
ICD-10 Finland
Diabetic background retinopathy
34.4
67.5
88
26
H3603, E103
ICD-10 Finland
NA
+∞
62.6
60
*
H25.8
ICD-10 Finland
Other senile cataract
2.2
61.8
730
3646
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
12.5
59.6
109
89
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
585.0
58.8
58
*
S01BC03
ATC
diclofenac; ophthalmic
5.6
58.0
175
320
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
49.2
56.2
68
14
H26.2
ICD-10 Finland
Complicated cataract
8.4
54.6
123
149
S01EC04
ATC
brinzolamide; ophthalmic
3.3
52.4
287
920
H20.1
ICD-10 Finland
Chronic iridocyclitis
10.8
51.2
100
94
H3601, E103
ICD-10 Finland
NA
+∞
51.1
49
*
S01EA03
ATC
apraclonidine; ophthalmic
10.5
50.9
101
98
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.8
50.9
230
634
H35.4
ICD-10 Finland
Peripheral retinal degeneration
175.1
50.0
52
*
H53.1
ICD-10 Finland
Subjective visual disturbances
2.8
49.7
348
1315
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.6
49.5
238
690
CKC60
NOMESCO Finland
Local buckling of sclera using implant
492.8
49.5
49
*
S01BC05
ATC
ketorolac; ophthalmic
3.4
49.2
252
768
A10AA02
ATC
NA
5.7
49.1
145
259
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.3
48.3
189
457
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
69.4
48.1
55
8
S01EE01
ATC
latanoprost; ophthalmic
2.5
48.0
404
1697
CKC15
NOMESCO Finland
Panretinal photocoagulation
89.3
47.9
53
6
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
46.9
45
*
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
5.3
46.4
147
285
A10AA01
ATC
NA
7.6
45.8
110
148
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
4.6
44.3
158
349
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
5.2
44.0
142
282
H3600, E103
ICD-10 Finland
NA
+∞
43.8
42
*
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.7
43.7
315
1209
S01ED01
ATC
timolol; ophthalmic
3.2
43.0
238
769
CKC30
NOMESCO Finland
Cryopexy of detached retina
421.2
42.2
42
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
113.5
41.8
45
*
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
60.6
41.2
48
8
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
411.0
41.2
41
*
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
48.4
39.8
48
10
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
390.5
39.1
39
*
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
390.5
39.1
39
*
WX110
NOMESCO Finland
Local anesthesy
1.5
39.0
2902
24269
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
3.8
38.8
173
472
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
196.5
37.8
39
*
1LA05
NOMESCO Finland
NA
+∞
37.5
36
*
H52.1
ICD-10 Finland
Myopia
4.8
36.4
125
266
H33.5
ICD-10 Finland
Other retinal detachments
14.7
36.2
61
42
ZX198
NOMESCO Finland
Other local administration
11.7
35.9
67
58
T89
ICPC
Diabetes insulin dependent
3.9
35.6
152
400
H35.9
ICD-10 Finland
Retinal disorder, unspecified
95.8
34.7
38
*
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
13.0
32.8
58
45
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
32.3
462
2459
H35.6
ICD-10 Finland
Retinal haemorrhage
319.1
31.9
32
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
319.1
31.9
32
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
114.1
31.7
34
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.6
31.3
148
425
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.2
30.4
322
1508
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
12.7
30.2
54
43
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.1
29.2
118
296
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.2
29.0
300
1390
S18
ICPC
Laceration/cut
1.4
28.9
2075
16773
H40.11
ICD-10 Finland
Low pressure glaucoma
3.3
28.9
153
480
CA1ME
NOMESCO Finland
Ultrasound oculometry
7.8
28.8
67
87
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.3
28.8
90
174
H30.2
ICD-10 Finland
Posterior cyclitis
150.9
28.7
30
*
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
2.7
28.0
195
733
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.1
28.0
161
536
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
6.9
27.4
69
101
A10AE04
ATC
insulin glargine; parenteral
1.9
27.4
421
2298
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.4
26.3
131
393
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
4.2
25.9
100
241
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
7.3
25.2
61
85
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
9.0
24.7
52
58
S01EE03
ATC
bimatoprost; ophthalmic
3.0
24.5
148
510
S01EC01
ATC
acetazolamide; systemic
3.6
24.4
114
326
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
11.3
24.1
45
40
CS494
NOMESCO Finland
Other visual field testing
3.1
23.6
135
448
R4110
NOMESCO Finland
Physiotherapy
1.4
23.5
1229
9259
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
21.4
23.4
34
16
H26.02
ICD-10 Finland
Presenil cataract
2.9
23.1
144
506
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.8
23.0
98
260
H3602, E113
ICD-10 Finland
NA
+∞
22.9
22
*
XCH05
NOMESCO Finland
Eye pressure longterm registration
4.6
22.4
79
175
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
21.9
21
*
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
+∞
21.9
21
*
H33.4
ICD-10 Finland
Traction detachment of retina
115.5
21.6
23
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.1
20.8
238
1156
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
4.6
20.8
73
162
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
77.1
20.7
23
*
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
110.5
20.6
22
*
F29
ICPC
Eye symptom/complaint other
1.8
20.5
356
2022
H43.3
ICD-10 Finland
Other vitreous opacities
3.9
20.5
85
221
S01EC54
ATC
brinzolamide, combinations; ophthalmic
3.8
20.4
87
232
N02BE01
ATC
paracetamol; systemic, rectal
1.4
19.2
3956
36884
H44.0
ICD-10 Finland
Purulent endophthalmitis
46.2
19.2
23
5
CKA10
NOMESCO Finland
Biopsy of vitreous body
34.4
18.9
24
7
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
8.4
18.9
41
49
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
3.0
18.8
110
373
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
18.7
2391
20648
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
11.8
18.7
34
29
E10
ICD-10 Finland
Type 1 diabetes mellitus
5.3
18.7
57
109
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
18.6
990
7435
J01DB01
ATC
cefalexin; oral
1.3
18.0
3522
32287
S01EE04
ATC
travoprost; ophthalmic
2.7
18.0
125
474
H04AA01
ATC
glucagon; nasal, parenteral
5.1
17.5
55
109
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
6.1
17.3
47
78
H34.2
ICD-10 Finland
Other retinal artery occlusions
42.1
17.3
21
5
S01EE05
ATC
tafluprost; ophthalmic
2.2
17.2
186
882
M79.6
ICD-10 Finland
Pain in limb
1.3
17.1
1485
12069
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
17.1
2119
18131
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
16.7
16
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
16.5
1448
11774
H40.9
ICD-10 Finland
Glaucoma, unspecified
2.9
16.3
99
344
S01EC03
ATC
dorzolamide; ophthalmic
3.4
16.2
79
236
Z71.8
ICD-10 Finland
Other specified counselling
1.4
16.2
875
6568
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
2.7
16.0
111
419
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
15.6
1682
14053
A02BC02
ATC
pantoprazole; systemic
1.3
15.5
2902
26090
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
15.3
479
3206
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.3
15.2
1332
10799
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
8.7
15.2
32
37
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
15.0
1108
8747
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
3.2
14.9
79
252
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
7.0
14.8
36
52
F05
ICPC
Visual disturbance other
2.4
14.6
123
518
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
4.8
14.6
48
101
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
14.6
14
*
A10AE05
ATC
insulin detemir; parenteral
1.9
14.5
205
1084
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
2.2
14.4
144
662
XCW10
NOMESCO Finland
Assessment of vision
6.2
14.3
38
62
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
6.6
14.3
36
55
WX320
NOMESCO Finland
Spinalanesthesy
1.3
14.2
1030
8096
N03AX16
ATC
pregabalin; oral
1.4
14.0
975
7611
H57.1
ICD-10 Finland
Ocular pain
2.4
13.9
117
495
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
13.8
2644
23651
E0000UV
ATC
NA
1.3
13.8
1528
12765
H53.2
ICD-10 Finland
Diplopia
2.2
13.7
137
631
L17
ICPC
Foot/toe symptom/complaint
1.3
13.6
1085
8647
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
75.3
13.6
15
*
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
140.3
13.4
14
*
S01GX01
ATC
cromoglicic acid; ophthalmic
1.4
13.3
604
4374
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
7.0
13.3
32
46
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
11.5
13.3
24
21
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
7.2
13.2
31
43
H20.8
ICD-10 Finland
Other iridocyclitis
7.2
13.2
31
43
XKD00
NOMESCO Finland
Uroflowmetry
1.4
13.2
830
6371
R01AD09
ATC
mometasone; nasal
1.3
13.1
1584
13356
H34.1
ICD-10 Finland
Central retinal artery occlusion
40.2
13.1
16
*
H33.2
ICD-10 Finland
Serous retinal detachment
40.2
13.1
16
*
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
12.2
13.1
23
19
177
Kela drug reimbursment
Insulin glargine 300 U / ml
2.9
13.0
80
282
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.5
12.9
59
170
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
12.7
785
6005
A10AA03
ATC
NA
6.4
12.6
32
50
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
24.3
12.4
17
7
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
12.4
1512
12738
S01EX03
ATC
NA
2.4
12.3
100
416
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
12.3
1828
15778
A10AE06
ATC
insulin degludec; parenteral
2.6
12.3
89
347
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.5
12.3
404
2733
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
12.1
875
6853
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
12.1
679
5105
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
12.1
1199
9834
H53.8
ICD-10 Finland
Other visual disturbances
3.5
12.0
55
159
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.6
11.9
323
2086
C10AA07
ATC
rosuvastatin; oral
1.3
11.9
1121
9124
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
11.9
2064
18119
M25.5
ICD-10 Finland
Pain in joint
1.3
11.8
1021
8208
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
11.8
1583
13478
KMAK
NOMESCO Finland
NA
1.3
11.7
1805
15620
H54.7
ICD-10 Finland
Unspecified visual loss
4.9
11.7
37
76
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
65.1
11.6
13
*
H27.1
ICD-10 Finland
Dislocation of lens
6.5
11.5
29
45
H02.3
ICD-10 Finland
Blepharochalasis
1.6
11.5
292
1859
C08CA01
ATC
amlodipine; oral
1.2
11.5
1746
15077
H3603, E107
ICD-10 Finland
NA
+∞
11.5
11
*
H3602, E103
ICD-10 Finland
NA
+∞
11.5
11
*
L03
ICPC
Low back symptom/complaint
1.3
11.3
919
7320
R42
ICD-10 Finland
Dizziness and giddiness
1.3
11.2
940
7516
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
9.6
11.2
22
23
R05
ICD-10 Finland
Cough
1.3
11.2
788
6145
H50.2
ICD-10 Finland
Vertical strabismus
4.2
11.2
41
98
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.9
11.2
155
819
D01AE16
ATC
amorolfine; topical
1.4
11.2
507
3669
C10AA05
ATC
atorvastatin; oral
1.2
11.0
1905
16669
S01ED02
ATC
betaxolol; ophthalmic
3.3
11.0
54
166
CS2P4
NOMESCO Finland
Optic nerve head imaging
4.4
10.9
38
87
AA1AD
NOMESCO Finland
CT of head and brain
1.3
10.8
1081
8851
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
10.8
1268
10596
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
11.9
10.8
19
16
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
10.8
1116
9178
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
10.7
675
5171
H16.0
ICD-10 Finland
Corneal ulcer
1.9
10.6
144
755
H43.2
ICD-10 Finland
Crystalline deposits in vitreous body
7.0
10.5
25
36
H26.9
ICD-10 Finland
Cataract, unspecified
2.6
10.4
77
304
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
10.4
10
*
H3601, E119
ICD-10 Finland
NA
+∞
10.4
10
*
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
+∞
10.4
10
*
G04CA02
ATC
tamsulosin; oral
1.3
10.4
1135
9391
H33
ICD-10 Finland
Retinal detachments and breaks
12.0
10.3
18
15
H81
ICPC
Excessive ear wax
1.3
10.1
770
6065
H13
ICPC
Plugged feeling ear
1.3
10.0
826
6584
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
9.9
1852
16276
L08
ICPC
Shoulder symptom/complaint
1.3
9.9
784
6213
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
9.8
957
7798
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.4
9.8
429
3078
CKD60
NOMESCO Finland
Anterior vitrectomy
3.5
9.8
44
127
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
10.6
9.8
18
17
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
2.8
9.7
61
219
H53.4
ICD-10 Finland
Visual field defects
2.3
9.7
88
387
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.7
9.7
214
1311
S82
ICPC
Naevus/mole
1.4
9.7
476
3494
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.8
9.6
172
990
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
2.7
9.6
65
247
H91.1
ICD-10 Finland
Presbycusis
1.5
9.5
290
1930
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
9.5
1032
8522
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
100.2
9.4
10
*
Z01.2
ICD-10 Finland
Dental examination
1.2
9.4
1428
12259
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
17.5
9.4
14
8
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
9.4
9
*
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
9.4
2005
17837
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
9.3
1092
9096
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
9.3
790
6316
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
9.3
2898
26749
CHC05
NOMESCO Finland
Iridotomy
2.3
9.2
80
348
M03BX02
ATC
tizanidine; oral
1.2
9.2
2281
20581
F38
ICPC
Eye, Other laboratory test NEC
4.2
9.1
33
79
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
4.8
9.1
29
61
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
9.1
1332
11380
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
3.6
9.1
39
109
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
9.1
1912
16965
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
6.2
9.1
23
37
M54.5
ICD-10 Finland
Low back pain
1.2
9.0
1166
9825
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
3.2
9.0
45
142
P06
ICPC
Sleep disturbance
1.5
8.9
301
2049
-1
NOMESCO Finland
NA
1.3
8.8
1073
8974
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
8.7
657
5161
H01.0
ICD-10 Finland
Blepharitis
1.7
8.7
171
1017
WX402
NOMESCO Finland
General anaesthesia
1.3
8.7
590
4562
N05CF02
ATC
zolpidem; oral
1.3
8.7
602
4671
S29
ICPC
Skin symptom/complaint other
1.3
8.6
703
5586
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
8.6
666
5254
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
3.8
8.6
34
89
H26.8
ICD-10 Finland
Other specified cataract
3.7
8.6
35
94
S22
ICPC
Nail symptom/complaint
1.6
8.6
233
1512
S02.51
ICD-10 Finland
Fracture of tooth, open
1.5
8.6
327
2290
G47.3
ICD-10 Finland
Sleep apnoea
1.3
8.5
779
6286
L01
ICPC
Neck symptom/complaint
1.4
8.5
483
3636
N17
ICPC
Vertigo/dizziness
1.4
8.5
471
3530
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
1.8
8.4
132
732
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
6.0
8.4
22
37
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
3.1
8.4
43
138
XF404
NOMESCO Finland
Ambulatory ECG
1.4
8.4
414
3041
CHD00
NOMESCO Finland
Laser trabeculoplasty
2.5
8.4
63
256
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
8.4
942
7797
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
2.0
8.4
105
537
D01BA02
ATC
terbinafine; oral; topical
1.3
8.4
1014
8469
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
7.8
8.3
18
23
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
8.3
8
*
L12
ICPC
Hand/finger symptom/complaint
1.4
8.3
496
3760
K02.1
ICD-10 Finland
Caries of dentine
1.2
8.3
1947
17407
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
2.2
8.3
81
372
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
8.3
941
7798
A10AD04
ATC
insulin lispro; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
5.5
8.3
23
42
CG2T4
NOMESCO Finland
Topography assessment of cornea
3.2
8.2
40
124
H02.4
ICD-10 Finland
Ptosis of eyelid
1.8
8.2
124
679
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
14.5
8.2
13
9
R01AD08
ATC
fluticasone; nasal
1.3
8.2
947
7867
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.6
8.1
214
1378
C10AX09
ATC
ezetimibe; oral
1.4
8.1
489
3711
N06AX21
ATC
duloxetine; oral
1.4
8.1
339
2417
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
8.1
681
5433
N02AX02
ATC
tramadol; systemic, rectal
1.2
8.0
1779
15809
J01FA10
ATC
azithromycin; systemic
1.2
7.9
1978
17767
L16
ICPC
Ankle symptom/complaint
1.4
7.9
351
2530
N05AD01
ATC
haloperidol; systemic
0.4
7.9
24
660
Z01.7
ICD-10 Finland
Laboratory examination
1.4
7.9
406
3007
J01CA04
ATC
amoxicillin; systemic
1.2
7.8
3221
30240
R06AX27
ATC
desloratadine; oral
1.3
7.8
758
6155
J01FF01
ATC
clindamycin; systemic
1.2
7.8
1020
8584
K85
ICPC
Elevated blood pressure
1.3
7.8
688
5521
R06.0
ICD-10 Finland
Dyspnoea
1.2
7.8
1043
8801
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
10.8
7.8
14
13
H25.9
ICD-10 Finland
Senile cataract, unspecified
2.2
7.8
73
333
M01AE01
ATC
ibuprofen; systemic, rectal
1.2
7.8
3689
35115
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
2.6
7.7
51
194
C09CA01
ATC
losartan; oral
1.2
7.7
1070
9066
H50.52
ICD-10 Finland
Exophoria
3.5
7.6
33
94
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
7.6
1274
11001
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.3
7.6
558
4362
SGA04
NOMESCO Finland
Very demanding opening and dilatation of root canal of tooth
1.5
7.6
258
1763
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.5
7.6
240
1615
H54.3
ICD-10 Finland
Mild or no visual impairment, binocular
8.0
7.6
16
20
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.3
7.6
655
5244
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
11.8
7.6
13
11
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.2
7.6
931
7777
J01FA06
ATC
roxithromycin; oral
1.2
7.6
1544
13594
ZXC20
NOMESCO Finland
Use of chemical agents
1.9
7.5
99
518
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
8.8
7.5
15
17
H02
ICPC
Hearing complaint
1.3
7.5
571
4490
SPAT1325
SPAT
Vaccination
1.2
7.5
1624
14374
C10AA01
ATC
simvastatin; oral
1.2
7.5
2240
20404
L15
ICPC
Knee symptom/complaint
1.3
7.5
851
7046
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.7
7.5
237
3340
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.5
7.5
256
1751
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.3
7.4
803
6606
H40.12
ICD-10 Finland
Pigmentary glaucoma
6.4
7.4
18
28
K80
ICPC
Cardiac arrhythmia NOS
1.4
7.4
314
2246
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
7.3
915
7652
H26.3
ICD-10 Finland
Drug-induced cataract
3.5
7.3
32
92
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.5
7.3
266
1844
H18.4
ICD-10 Finland
Corneal degeneration
3.9
7.3
28
72
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
3.3
7.3
34
103
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
7.3
7
*
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
3.4
7.3
33
98
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.5
7.3
232
1566
-44
ICPC
Preventive immunization/medic
1.4
7.3
372
2752
D19
ICPC
Teeth/gum symptom/complaint
1.3
7.3
816
6746
VALMI
NOMESCO Finland
NA
1.3
7.2
752
6161
Z01.9
ICD-10 Finland
Special examination, unspecified
1.5
7.2
219
1463
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.5
7.2
251
1726
M01AH05
ATC
etoricoxib; oral
1.2
7.2
2214
20189
J01DA06
ATC
[U] cefuroxime; systemic
1.3
7.2
508
3953
M02AA07
ATC
piroxicam; topical
1.2
7.2
1531
13518
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
7.2
1596
14148
H18.8
ICD-10 Finland
Other specified disorders of cornea
3.9
7.1
27
69
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.5
7.1
262
1820
H21.0
ICD-10 Finland
Hyphaema
4.8
7.1
22
46
A02BC05
ATC
esomeprazole; systemic
1.2
7.1
1636
14543
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.4
7.1
291
2066
F43
ICPC
Eye, Other diagnostic procedure
2.1
7.1
75
360
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.5
7.1
228
1543
H47.3
ICD-10 Finland
Other disorders of optic disc
6.0
7.1
18
30
M01AB05
ATC
diclofenac; systemic, rectal
1.2
7.1
2628
24335
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
1.2
7.0
809
6705
A11
ICPC
Chest pain NOS
1.4
7.0
315
2277
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
7.0
641
5165
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.5
7.0
247
1702
U02
ICPC
Urinary frequency/urgency
1.3
7.0
507
3960
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
1.6
7.0
181
1163
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.2
6.9
928
7820
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.3
6.9
778
6426
H50.1
ICD-10 Finland
Divergent concomitant strabismus
3.8
6.9
27
71
SPAT1262
SPAT
Handing over of treatment supplies
1.3
6.9
765
6305
H52.2
ICD-10 Finland
Astigmatism
2.5
6.9
49
194
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
2.1
6.9
76
370
T78.4
ICD-10 Finland
Allergy, unspecified
1.8
6.9
115
655
171
Kela drug reimbursment
Degludekinsuliini
13.8
6.9
11
8
N03AX12
ATC
gabapentin; oral
1.3
6.8
580
4628
R51.80
ICD-10 Finland
Headache
1.3
6.8
416
3164
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
6.8
1165
10067
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
6.7
6.8
16
24
R4120
NOMESCO Finland
Occupational therapy
1.5
6.8
223
1514
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.4
6.7
318
2321
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.2
6.7
802
6670
H02AB07
ATC
prednisone; oral
1.3
6.7
538
4261
F99
ICPC
Eye/adnexa disease other
3.4
6.7
30
89
207
Kela drug reimbursment
Chronic arrhythmias
1.3
6.7
712
5844
UJF32
NOMESCO Finland
Coloscopy
1.2
6.7
1140
9843
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
6.7
1656
14797
103
Kela drug reimbursment
Diabetes, insulin-treated
1.2
6.6
1129
9742
H84
ICPC
Presbyacusis
1.6
6.6
159
1005
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.3
6.6
520
4106
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.2
6.6
762
6313
A29
ICPC
General symptom/complaint other
1.3
6.6
437
3366
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.0
6.6
83
428
C07AB07
ATC
bisoprolol; oral
1.2
6.6
2245
20582
R53
ICD-10 Finland
Malaise and fatigue
1.3
6.6
729
6009
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
7.8
6.6
14
18
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.3
6.5
556
4435
TUPEI
NOMESCO Finland
NA
1.8
6.5
106
598
G04CA01
ATC
alfuzosin; oral
1.3
6.5
527
4179
R03AC02
ATC
salbutamol; inhalant
1.2
6.5
1950
17693
K59.09
ICD-10 Finland
Constipation, unspecified
1.4
6.4
246
1725
CJB40
NOMESCO Finland
Laser anterior capsulotomy
69.9
6.4
7
*
1BA01
NOMESCO Finland
NA
69.9
6.4
7
*
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
2.7
6.4
39
143
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.5
6.4
47
934
R06AE07
ATC
cetirizine; oral
1.2
6.4
1496
13285
3643
FHL
Vitrectomy through pars Plana
14.3
6.4
10
7
TPH04
NOMESCO Finland
Cathetrisation of vein
1.2
6.4
839
7051
J01MA02
ATC
ciprofloxacin; systemic
1.2
6.4
1628
14566
H29
ICPC
Ear symptom/complaint other
1.3
6.4
401
3068
M86.6
ICD-10 Finland
Other chronic osteomyelitis
4.4
6.3
21
48
H44.2
ICD-10 Finland
Degenerative myopia
8.1
6.3
13
16
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.4
6.3
337
2513
XF402
NOMESCO Finland
ECG with work load test
1.3
6.3
493
3889
CHD99
NOMESCO Finland
Other filtering operation
5.2
6.3
18
35
NF1AA
NOMESCO Finland
Hip X-ray examination
1.3
6.3
386
2941
K30
ICD-10 Finland
Functional dyspepsia
1.4
6.3
361
2722
37600
ICD-8 Finland
Detachment of retina, Primaria
+∞
6.2
6
*
H30.1
ICD-10 Finland
Disseminated chorioretinal inflammation
+∞
6.2
6
*
3625F
ICD-9 Finland
Other retinal disorders, Degeneration of macula and posterior pole[FIBROSIS PRAERETINALIS]
+∞
6.2
6
*
NHQ40
NOMESCO Finland
Amputation of toe
2.1
6.2
65
313
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
6.2
350
2631
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
1.9
6.2
80
419
T90
ICPC
Diabetes non-insulin dependent
1.2
6.2
1011
8687
H53
ICD-10 Finland
Visual disturbances
3.2
6.2
29
90
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.4
6.1
278
2015
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.5
6.1
170
1113
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
4.2
6.1
21
50
WX203
NOMESCO Finland
Infraclavicular plexus blockade
1.9
6.1
77
400
A01
ICPC
Pain general/multiple sites
1.4
6.1
284
2068
R20.2
ICD-10 Finland
Paraesthesia of skin
1.5
6.1
194
1312
R21
ICPC
Throat symptom/complaint
1.3
6.1
474
3740
S21
ICPC
Skin texture symptom/complaint
1.3
6.1
501
3984
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.3
6.1
419
3252
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.3
6.1
633
5181
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
6.0
1248
10951
B01AB05
ATC
enoxaparin; parenteral
1.2
6.0
1341
11847
WX144
NOMESCO Finland
Subconjunctival anesthesy
2.2
6.0
56
257
H40
ICD-10 Finland
Glaucoma
2.2
6.0
53
237
N06AX16
ATC
venlafaxine; oral
1.3
6.0
366
2787
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5384
49467
7.27
88.30
28.6
25.1
6.7
6.8
e9/l
3.03
5201
47772
5384
49469
7.27
88.25
28.8
25.2
133.0
133.5
g/l
1.53
5305
48604
5382
49452
7.11
87.85
28.6
25.0
239.4
242.3
e9/l
2.63
5223
47962
5326
48553
4.92
87.82
23.2
20.2
4.0
4.0
mmol/l
0.01
5211
47272
5382
49463
7.09
87.58
28.6
25.0
4.4
4.4
e12/l
1.65
5200
47768
5319
48478
4.74
87.00
22.9
20.0
139.6
139.7
mmol/l
0.60
5206
47267
5304
48352
4.37
84.48
12.9
11.6
24.4
25.0
u/l
1.24
5064
46259
5135
46109
2.90
80.43
6.1
5.5
2.6
2.6
mmol/l
2.76
4576
41453
4908
43328
2.31
76.82
18.4
16.2
72.3
73.8
ml/min/173m2
6.14
4111
35845
4284
36164
1.86
74.49
23.6
20.8
13.8
13.9
%
0.87
4193
35347
5011
44843
2.43
72.25
5.2
4.9
4.5
4.5
mmol/l
1.63
4463
40515
4911
43714
2.23
69.45
7.4
6.5
41.2
40.4
mmol/mol
5.34
4452
39602
5053
45560
2.46
68.50
18.8
16.8
25.5
26.6
mg/l
1.43
4077
36962
4770
42065
2.06
68.03
5.3
4.9
2.5
2.1
mu/l
0.35
4253
37534
4963
44438
2.28
67.91
5.2
4.8
1.5
1.5
mmol/l
2.39
4377
39812
4469
38825
1.83
62.99
22.0
18.5
39.0
38.6
%
1.83
2935
23713
4799
42920
1.97
58.07
4.6
4.3
1.2
1.3
mmol/l
2.69
4196
38027
5007
45508
2.21
57.41
5.6
5.2
6.1
6.1
mmol/l
3.99
4425
40553
2647
20515
1.56
55.31
11.2
10.4
0.0
0.0
e9/l
0.12
2168
16701
4020
34453
1.63
53.04
4.2
4.0
15.0
15.1
pmol/l
0.35
3525
30615
2821
22457
1.53
50.27
2.2
2.1
97.1
93.9
pmol/l
2.88
1383
11510
4076
35242
1.62
49.85
4.8
4.3
14.5
14.1
mm/h
0.79
3679
32134
4334
38091
1.67
49.18
8.2
7.9
80.0
80.1
u/l
0.05
4033
35690
2347
18222
1.51
45.38
3.1
2.8
152.3
160.7
ug/l
0.76
2096
16478
3001
24520
1.50
45.05
6.7
6.0
1.2
1.2
mmol/l
2.09
2706
21999
2331
18109
1.50
44.72
4.3
3.9
105.2
111.1
e6/l
0.08
1663
13145
1717
12535
1.54
44.06
4.4
4.1
85.5
86.0
%
0.37
1673
12249
1957
14724
1.51
43.47
3.7
3.3
0.4
0.5
e6/l
0.68
1485
11172
3799
32863
1.51
41.10
5.4
4.9
718.4
1492.8
e6/l
0.54
32
513
2069
15903
1.48
40.65
3.7
3.5
119.4
80.3
e6/l
0.28
1573
12322
2912
23930
1.46
40.54
6.5
5.7
1.8
1.9
e9/l
2.38
2515
20669
3203
26833
1.47
40.20
7.5
6.7
1.2
1.2
mmol/l
2.98
2682
22545
2944
24303
1.46
39.63
6.6
5.8
0.2
0.2
e9/l
0.39
2521
20955
3269
27611
1.46
38.47
9.2
9.1
4.2
4.2
e9/l
0.75
2817
23914
2707
22131
1.44
37.49
6.6
5.9
58.1
58.2
%
0.05
2507
20464
2734
22473
1.43
36.29
6.9
6.1
26.5
26.6
%
0.08
2526
20675
2688
22040
1.43
36.09
6.8
5.9
2.9
2.8
%
1.11
2482
20342
2454
19797
1.44
35.99
2.4
2.2
80.7
79.8
nmol/l
0.76
2121
17273
1703
12938
1.46
33.94
1.7
1.6
1.3
1.3
mmol/l
1.25
1391
10643
1201
8502
1.53
33.93
3.3
3.2
2.1
2.2
e6/l
0.21
674
4735
1280
9200
1.51
33.62
3.1
2.9
1.4
1.5
e6/l
0.05
751
5403
1709
13213
1.43
30.18
1.6
1.6
20.6
20.4
nmol/l
0.26
1430
11126
1698
13128
1.43
29.93
2.4
2.3
2.9
3.0
mg/l
1.25
1419
11116
2720
22800
1.38
29.73
5.3
4.8
34.9
34.8
g/l
0.60
2501
21055
3425
29864
1.39
29.23
5.3
4.8
6.9
6.8
mmol/l
3.69
3240
28040
2546
21253
1.37
27.82
2.3
2.2
—
—
—
0
0
2190
17845
1.38
27.81
3.4
3.4
2.4
2.4
mmol/l
0.11
1841
15177
1392
10524
1.43
27.27
4.2
4.0
530.2
492.2
ng/l
0.09
1211
8995
2743
23295
1.36
26.24
5.7
5.3
0.0
0.0
estimate
0.50
521
4317
1352
10249
1.42
25.87
3.1
3.2
2.5
2.5
mmol/l
0.58
1195
8947
2729
23211
1.35
25.58
4.3
4.0
0.0
0.0
estimate
0.50
525
4287
2764
23577
1.35
25.30
4.3
4.0
0.0
0.0
estimate
0.34
506
4223
1986
16105
1.37
25.27
2.2
2.2
187.1
214.9
u/l
0.74
1839
14991
998
7242
1.46
23.92
3.1
2.6
22.3
21.9
%
0.39
851
6071
1436
11138
1.39
23.71
3.4
3.4
0.8
0.8
ug/l
0.79
1095
8237
2017
16527
1.35
23.52
3.6
3.2
455.8
369.4
mg/l
0.33
1261
10339
1031
7569
1.45
23.16
1.6
1.5
2.7
2.6
g/l
0.25
561
4192
1110
8261
1.43
23.15
3.0
2.5
12.5
12.3
umol/l
0.54
1015
7596
1118
8338
1.43
23.03
2.0
2.0
30.1
30.0
s
0.25
1088
8099
1140
8533
1.42
23.01
1.4
1.2
1.6
1.8
u/ml
0.11
269
2048
1040
7656
1.44
23.00
3.0
2.5
2.2
2.3
g/l
0.89
946
7038
2034
16734
1.34
22.92
3.5
3.1
6.9
7.2
mmol/l
2.35
1633
13758
2634
22511
1.33
22.82
10.7
10.6
1.3
1.3
inr
0.79
765
6064
3044
26561
1.33
22.80
6.0
6.4
12.4
12.0
umol/l
0.68
2870
25206
2090
17294
1.34
22.54
3.3
3.1
1812.2
1476.0
ng/l
1.62
1811
15121
3068
26831
1.33
22.46
3.3
3.2
54.6
54.2
u/l
0.08
2750
24210
2320
19566
1.32
21.64
6.0
5.7
3.2
3.9
ug/l
0.80
2051
17342
1429
11239
1.37
21.23
2.9
2.7
4.5
4.8
e6/l
0.47
1233
9815
2084
17437
1.32
20.10
4.5
3.9
11.9
8.2
mg/mmol
2.82
1266
10791
647
4525
1.49
18.34
2.5
2.4
36.2
38.5
u/l
0.29
549
3866
692
4908
1.47
18.27
2.4
2.6
65.9
66.1
g/l
0.21
611
4389
1616
13187
1.32
18.19
3.0
2.9
4940.0
5403.6
umol/l
0.16
1351
11135
753
5492
1.43
17.07
2.8
2.6
9.1
9.3
umol/l
0.12
667
4803
1877
15743
1.29
16.96
5.0
4.9
22.3
22.1
%
0.34
1025
8618
871
6583
1.38
15.99
2.4
2.4
1.8
1.8
%
0.00
758
5810
946
7269
1.36
15.64
1.3
1.3
36.6
41.9
iu/ml
0.59
299
2168
740
5527
1.39
14.49
3.6
3.7
—
—
—
0
0
378
2494
1.55
14.01
5.1
3.9
24.0
24.3
mmol/l
0.98
339
2229
1697
14363
1.26
13.48
3.3
3.3
31.4
36.6
u/l
2.91
1567
13502
574
4169
1.42
13.16
4.4
3.6
98.8
93.6
ng/l
0.52
481
3519
487
3432
1.46
13.14
1.8
1.7
—
—
—
0
0
877
6851
1.33
12.78
1.3
1.2
14.6
15.4
u/ml
0.09
250
2370
644
4799
1.39
12.71
6.5
6.4
1.3
1.3
mmol/l
0.14
626
4632
436
3028
1.48
12.68
2.4
2.1
12.0
11.6
nmol/l
0.39
372
2571
334
2194
1.56
12.63
1.9
2.3
9.8
10.2
g/l
0.94
263
1820
310
2002
1.58
12.63
2.0
2.4
1.0
1.0
g/l
0.04
250
1700
288
1833
1.60
12.48
1.6
2.2
37.7
37.2
g/l
0.62
230
1543
979
7820
1.31
12.12
31.7
28.3
1.4
1.4
inr
0.13
89
1098
879
6933
1.32
11.91
7.1
5.4
1.1
1.0
mmol/l
3.41
802
6397
831
6520
1.32
11.67
3.6
4.3
244.1
245.4
u/l
0.10
778
6123
348
2355
1.51
11.49
1.9
2.4
—
—
—
0
0
348
2355
1.51
11.49
1.9
2.4
7.6
7.5
g/l
0.57
247
1740
1315
10976
1.26
11.39
1.9
1.8
1241.8
1160.5
nmol/l
2.17
920
8142
1100
8987
1.28
11.37
1.9
1.9
—
—
—
0
0
1207
9985
1.27
11.26
1.6
1.7
1.7
1.5
mg/l
0.46
937
7829
346
2350
1.50
11.23
1.9
2.4
3.9
3.8
g/l
0.77
240
1666
327
2197
1.52
11.18
1.9
2.4
3.2
3.1
g/l
0.87
244
1695
288
1883
1.56
11.14
2.0
1.7
41.8
38.2
u/l
2.25
253
1587
248
1574
1.60
10.90
1.3
1.2
3.2
1.1
u/ml
0.70
24
165
250
1597
1.59
10.70
1.7
2.4
0.0
0.0
g/l
0.00
224
1457
2566
23113
1.21
10.47
4.2
4.2
—
—
—
0
0
661
5094
1.34
10.45
2.8
2.6
67.8
68.4
e9/l
0.15
479
3881
2266
20185
1.21
10.34
4.4
4.0
140.4
72.1
ng/l
0.39
1767
15546
68
287
2.39
10.16
1.3
1.2
31.6
21.9
u/l
0.66
55
244
267
1754
1.55
10.14
1.7
2.3
0.0
0.0
g/l
0.08
240
1584
106
540
1.98
9.91
1.3
1.2
55.9
64.3
u/l
0.76
66
364
69
297
2.34
9.88
1.3
1.2
109.2
84.6
u/l
0.94
56
258
250
1630
1.56
9.83
1.7
2.4
0.0
0.0
g/l
0.50
224
1464
437
3184
1.40
9.81
6.3
6.8
25.1
24.9
mmol/l
0.29
437
3165
1052
8690
1.26
9.77
3.0
3.1
0.8
0.8
mmol/l
1.18
967
8073
781
6218
1.30
9.75
1.8
1.8
—
—
—
0
0
531
4005
1.36
9.66
2.3
2.3
380.5
374.7
nmol/l
0.26
481
3651
395
2841
1.42
9.54
2.4
2.4
34.7
29.7
au/ml
0.14
13
80
386
2771
1.42
9.43
1.5
1.7
1.5
1.6
g/l
0.73
326
2376
195
1211
1.63
9.41
1.8
1.7
—
—
—
0
0
115
619
1.88
9.17
1.6
1.3
122.0
127.5
u/ml
0.15
21
120
453
3364
1.38
9.08
2.9
2.8
10.8
10.4
g/l
0.66
409
3053
779
6258
1.29
9.04
1.8
1.8
—
—
—
0
0
359
2568
1.43
8.95
1.3
1.3
56.5
54.7
au/ml
0.04
12
105
597
4639
1.32
8.87
1.9
2.0
139.2
154.9
ug/g
0.42
459
3560
155
925
1.70
8.75
1.3
1.2
—
—
—
0
0
293
2029
1.47
8.69
2.5
3.4
45.2
50.4
mg/l
0.22
229
1668
345
2464
1.43
8.68
3.3
3.2
4.4
4.4
pmol/l
0.03
301
2126
408
3001
1.39
8.67
8.1
8.5
24.3
24.4
mmol/l
0.37
377
2792
293
2030
1.47
8.67
2.5
3.4
70.8
87.1
mg/l
0.21
226
1666
199
1282
1.57
8.30
1.2
1.2
—
—
—
0
0
197
1269
1.57
8.22
1.2
1.2
—
—
—
0
0
131
771
1.72
7.82
1.4
1.2
26.2
50.0
u/ml
1.41
19
81
281
1974
1.45
7.76
2.5
3.4
4.3
3.2
ratio
0.20
19
150
195
1281
1.54
7.49
2.5
2.3
124.4
97.5
ug/min
0.33
109
731
226
1545
1.48
7.20
1.8
1.7
—
—
—
0
0
1473
12941
1.19
7.15
4.9
4.4
0.0
0.0
estimate
0.20
500
4125
840
7032
1.23
6.72
7.2
6.6
104.3
104.4
mmol/l
0.31
829
6868
132
820
1.62
6.49
1.4
1.3
—
—
—
0
0
790
6609
1.23
6.35
6.6
6.7
0.9
1.1
mmol/l
1.16
625
5168
491
3890
1.29
6.32
1.6
1.6
—
—
—
0
0
609
4956
1.26
6.29
9.0
6.4
11.7
10.5
mmol/l
3.14
580
4696
791
6652
1.22
6.03
6.6
6.7
12.2
12.0
kpa
0.50
755
6335
791
6654
1.22
6.01
6.7
6.7
5.1
5.1
kpa
0.35
754
6346
231
1649
1.42
5.92
1.1
1.1
—
1.3
—
0
22
225
1601
1.42
5.88
1.3
1.2
—
—
—
0
0
509
4096
1.27
5.79
3.1
2.7
57.6
61.0
ml/min/173m2
1.37
203
1683
159
1061
1.51
5.77
1.6
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
282
2099
1.36
5.65
2.5
2.8
0.3
0.4
u/ml
0.67
151
1187
614
5062
1.24
5.65
4.8
3.6
1.5
2.0
mmol/l
2.62
509
4135
93
549
1.71
5.61
2.0
1.8
201.7
188.9
pmol/l
0.29
85
507
167
1134
1.49
5.59
1.4
1.2
33.1
32.6
u/ml
0.01
18
57
60
310
1.95
5.57
1.1
1.1
—
—
—
0
0
1927
17565
1.15
5.55
4.8
4.3
—
—
—
0
0
177
1218
1.47
5.55
3.3
2.8
1.9
1.7
mg/l
1.39
153
1083
157
1055
1.50
5.53
1.4
1.2
2.7
3.4
u/ml
0.18
19
106
553
4523
1.25
5.47
4.5
3.9
1.2
1.2
mmol/l
0.60
476
3971
185
1288
1.45
5.46
1.9
1.7
—
—
—
0
0
158
1068
1.49
5.42
1.4
1.2
4.1
4.9
u/ml
0.21
29
165
1742
15793
1.15
5.38
2.7
2.6
61.8
58.8
u/l
0.63
1558
14449
175
1226
1.44
5.03
1.9
1.5
0.2
0.2
g/l
0.56
164
1152
607
5087
1.22
4.78
4.8
3.6
5.8
5.8
kpa
1.22
591
4938
84
507
1.67
4.73
1.4
1.2
26.8
58.0
u/ml
—
10
38
207
1521
1.38
4.56
1.5
1.4
281.8
269.0
ug/g
0.49
119
927
177
1268
1.41
4.54
1.8
1.5
1.2
1.2
g/l
0.02
166
1192
503
4161
1.23
4.50
4.0
3.0
4.7
4.5
kpa
0.94
488
4027
239
1802
1.34
4.48
1.1
1.1
—
—
—
0
0
171
1221
1.41
4.47
2.2
1.8
12.6
12.1
mg/l
0.36
162
1109
645
5488
1.20
4.34
7.3
7.4
117.6
120.4
g/l
3.05
628
5271
15
45
3.34
4.32
5.1
4.8
—
—
—
0
0
43
220
1.96
4.19
1.1
1.1
—
—
—
0
0
386
3130
1.25
4.17
1.6
1.5
—
—
—
0
0
51
279
1.84
4.08
2.3
2.0
—
—
—
0
0
1375
12461
1.14
4.08
2.6
2.5
—
—
—
0
0
21
80
2.63
4.05
1.0
1.1
—
—
—
0
0
90
579
1.56
3.98
3.7
3.5
—
—
—
0
0
159
1148
1.40
3.95
1.3
1.3
—
—
—
0
0
159
1148
1.40
3.95
1.3
1.3
—
—
—
0
0
187
1387
1.36
3.94
1.6
1.6
—
—
—
0
0
82
518
1.59
3.92
1.2
1.2
3.8
4.9
u/ml
0.46
40
217
26
113
2.31
3.84
1.2
1.2
—
—
—
0
0
35
174
2.02
3.73
29.0
27.5
103.1
109.5
ug/l
0.29
30
147
123
859
1.44
3.70
1.4
1.5
30.1
32.2
g/l
1.00
108
767
430
3578
1.22
3.67
1.6
1.6
1.7
1.6
%
1.35
352
2946
178
1327
1.35
3.66
2.0
2.3
3.7
3.6
g/l
0.14
167
1261
83
536
1.56
3.64
1.3
1.2
2.0
5.2
u/ml
1.22
31
166
52
298
1.75
3.62
1.3
1.1
—
—
—
0
0
58
343
1.70
3.61
1.3
1.2
197.7
130.6
titre
0.30
13
54
540
4606
1.19
3.56
1.3
1.3
—
—
—
0
0
163
1205
1.36
3.54
1.6
1.6
0.9
11.3
iu/ml
1.08
45
290
93
620
1.51
3.54
1.3
1.3
14.5
12.1
u/l
0.54
74
493
285
2278
1.26
3.52
1.1
1.2
112.8
127.2
iu/ml
0.32
77
786
577
4964
1.18
3.45
2.4
2.1
0.2
0.2
g/l
0.56
526
4610
51
296
1.73
3.41
2.4
2.2
160.8
202.0
ug/min
0.11
13
72
94
635
1.49
3.38
1.2
1.2
—
—
—
0
0
179
1354
1.33
3.37
3.3
3.1
0.9
0.8
nmol/l
0.34
135
1045
57
343
1.67
3.36
1.3
1.2
74.0
110.0
titre
—
5
9
87
581
1.51
3.31
1.2
1.2
310.0
290.9
u/ml
0.25
58
359
162
1215
1.34
3.24
4.4
4.4
2.5
2.8
mmol/l
0.64
132
845
241
1909
1.27
3.24
2.2
2.2
275.8
638.7
ug/l
1.76
232
1801
162
1216
1.34
3.23
4.4
4.4
5.1
5.0
kpa
0.66
162
1199
169
1281
1.33
3.16
1.7
1.5
—
—
—
0
0
169
1281
1.33
3.16
2.4
2.2
129.8
126.5
g/l
0.91
114
918
53
319
1.67
3.14
1.5
1.6
5.7
7.0
u/l
0.27
23
150
17
67
2.54
3.12
10.5
12.4
4.7
5.2
mmol/l
0.61
17
67
106
747
1.43
3.10
1.5
1.5
1155.4
2259.8
e6/l
2.03
73
528
158
1193
1.33
3.05
1.9
2.4
215.1
206.9
%
0.50
140
1137
7
12
5.84
3.02
1.3
1.0
—
—
—
0
0
44
255
1.73
3.00
1.6
1.5
5.5
7.1
u/l
1.00
35
209
133
981
1.36
2.99
1.6
1.7
5.7
4.7
iu/l
0.23
35
284
76
1113
0.68
2.89
3.5
3.6
26.8
30.2
mg/l
0.44
47
703
97
684
1.43
2.85
1.5
1.5
81836.3
61620.2
e6/l
0.19
55
396
28
143
1.96
2.84
1.4
1.1
—
—
—
0
0
124
916
1.36
2.79
1.4
1.2
7.5
6.3
u/ml
0.07
19
63
9
23
3.92
2.77
3.4
3.3
—
—
—
0
0
103
739
1.40
2.76
1.2
1.2
—
—
—
0
0
587
5153
1.16
2.75
2.7
2.4
6.5
7.1
ug/l
0.42
501
4459
123
914
1.35
2.68
1.4
1.4
—
—
—
0
0
165
1284
1.29
2.61
1.8
2.1
87.8
88.0
%
0.02
154
1219
57
368
1.55
2.60
1.2
1.2
—
—
—
0
0
82
574
1.44
2.55
1.3
1.3
298.6
369.3
u/l
0.83
77
539
34
193
1.77
2.53
1.1
1.1
5.5
13.0
iu/ml
—
6
46
102
748
1.37
2.44
6.2
6.3
11.4
12.2
mg/l
1.09
95
683
83
588
1.42
2.43
1.0
1.1
67.8
750.0
iu/ml
0.78
13
103
33
189
1.75
2.40
1.3
1.2
—
—
—
0
0
153
1197
1.29
2.36
2.9
2.6
16.2
15.9
%
0.48
82
644
69
476
1.46
2.34
1.3
1.3
45.0
37.4
iu/l
0.87
52
391
1237
11476
1.10
2.30
1.8
1.7
48498301.6
30979982.8
pmol/l
0.36
932
9290
760
6873
1.12
2.28
9.2
7.6
—
—
—
0
0
593
5298
1.13
2.18
2.7
2.9
230.1
208.9
ng/l
0.52
545
4869
116
895
1.30
2.03
1.1
1.1
—
—
—
0
0
565
5059
1.13
2.02
1.4
1.3
—
—
—
0
0
136
1074
1.27
2.00
2.8
2.5
36.2
34.1
umol/l
0.27
105
892
22
119
1.85
1.96
1.6
1.4
22.5
27.3
g/l
0.51
14
98
7
21
3.34
1.96
7.3
13.1
53.7
179.7
e6/l
—
7
16
7
21
3.34
1.96
1.1
1.0
—
—
—
0
0
55
380
1.45
1.91
1.3
1.3
288.0
318.8
titre
—
5
42
54
374
1.45
1.86
1.1
1.2
95.9
92.1
%
0.53
49
343
20
107
1.87
1.85
2.4
1.9
0.7
1.1
ug/l
0.71
20
100
75
557
1.35
1.75
1.9
1.7
888.1
314.1
mu/l
0.56
67
511
10
41
2.44
1.75
1.1
1.1
—
—
—
0
0
30
186
1.62
1.71
1.1
1.1
—
—
—
0
0
120
956
1.26
1.69
1.3
1.2
7.2
6.8
u/ml
—
8
9
29
179
1.62
1.69
1.1
1.4
7.9
17.7
umol/l
0.78
23
110
20
111
1.80
1.68
1.2
1.1
1393.3
1591.1
miu/ml
0.35
20
111
7
25
2.80
1.65
1.0
1.0
—
—
—
0
0
5
130
0.38
1.62
1.0
1.1
—
—
—
0
0
32
205
1.56
1.62
1.6
1.3
127.1
49.9
pmol/l
—
6
73
195
1644
1.19
1.61
1.3
1.3
—
—
—
0
0
55
396
1.39
1.58
1.2
1.2
1.4
1.6
nmol/l
0.55
45
360
89
690
1.29
1.58
2.4
2.4
1780.0
2132.0
u/ml
—
5
48
288
2513
1.15
1.57
3.7
2.5
0.6
0.7
%
0.21
276
2399
87
673
1.30
1.57
1.1
1.3
0.2
0.3
nmol/l
—
8
50
46
321
1.44
1.57
1.0
1.0
—
—
—
0
0
31
199
1.56
1.56
1.2
1.4
3.7
2.6
%
0.28
23
170
112
896
1.26
1.55
5.8
4.5
1272.3
3409.3
iu/ml
0.48
18
128
91
710
1.29
1.54
1.8
1.8
89.3
89.0
%
0.16
91
700
41
283
1.45
1.49
1.3
1.1
—
—
—
0
0
86
670
1.29
1.49
1.1
1.3
0.7
0.7
nmol/l
0.48
81
641
67
504
1.33
1.48
1.1
1.1
—
—
—
0
0
64
479
1.34
1.47
1.1
1.2
115.7
114.1
%
0.15
55
413
41
284
1.45
1.47
1.3
1.1
—
—
—
0
0
261
2276
1.15
1.45
1.3
1.3
121.5
255.7
u/ml
5.70
235
2059
7
28
2.50
1.45
1.1
1.1
—
—
—
0
0
41
285
1.44
1.45
1.3
1.1
—
—
—
0
0
41
285
1.44
1.45
1.3
1.1
—
—
—
0
0
41
285
1.44
1.45
1.3
1.1
—
—
—
0
0
240
2083
1.16
1.43
2.3
2.7
—
—
—
0
0
40
278
1.44
1.42
2.2
2.3
651.5
571.7
e6/l
0.32
17
120
34
229
1.49
1.41
1.2
1.4
62.0
68.0
%
0.40
24
187
33
221
1.50
1.40
1.2
1.0
—
—
—
0
0
149
1246
1.20
1.39
3.2
2.9
7.8
7.9
kpa
0.06
138
1146
5
123
0.41
1.36
1.0
1.1
—
—
—
0
0
5
124
0.40
1.36
1.0
1.1
—
—
—
0
0
32
465
0.69
1.33
1.1
1.2
6.5
7.8
mmol/l
1.88
23
333
124
1025
1.21
1.31
1.2
1.3
48.0
211.3
titre
—
5
23
113
927
1.22
1.29
1.3
1.4
17.5
31.6
e6/l
0.70
80
704
235
2055
1.15
1.29
4.3
3.9
1.3
1.4
mmol/l
0.35
230
2015
5
18
2.78
1.28
1.0
1.3
—
—
—
0
0
113
930
1.22
1.26
1.4
1.4
1690.1
992.7
e6/l
0.38
85
751
203
1761
1.16
1.25
4.5
4.1
3.8
3.9
mmol/l
1.50
196
1646
5
117
0.43
1.24
1.0
1.1
—
—
—
0
0
12
63
1.91
1.22
1.6
1.5
—
—
—
0
0
12
63
1.91
1.22
1.1
1.4
—
—
—
0
0
56
425
1.32
1.22
2.5
2.2
598.3
645.7
ml
0.46
37
277
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
127
1066
1.20
1.18
1.6
1.7
3.4
3.7
mg/l
0.09
99
775
60
463
1.30
1.17
1.6
1.8
4.1
4.5
mg/l
0.39
55
436
6
129
0.46
1.16
1.0
1.1
—
—
—
0
0
154
1318
1.17
1.15
1.6
1.6
12078.3
14378.8
e6/l
0.38
112
930
14
234
0.60
1.13
1.1
1.2
5.7
6.2
mmol/l
2.06
14
217
33
233
1.42
1.12
1.4
1.2
0.9
1.2
nmol/l
1.42
23
178
127
1073
1.19
1.11
1.5
1.4
—
—
—
0
0
13
73
1.78
1.10
1.2
1.0
—
—
—
0
0
5
21
2.38
1.09
3.4
2.0
—
—
—
0
0
48
627
0.76
1.08
1.3
1.4
—
—
—
0
0
31
219
1.42
1.06
1.0
4.3
54.2
65.7
mg/l
0.64
23
161
52
400
1.30
1.06
1.1
1.2
—
—
—
0
0
9
46
1.96
1.03
1.6
1.4
—
—
—
0
0
69
553
1.25
1.03
3.5
3.0
—
—
—
0
0
71
571
1.25
1.03
1.2
1.1
1.6
1.5
g/l
0.08
61
508
16
98
1.63
1.03
1.0
1.2
79.7
83.1
%
—
7
45
31
221
1.41
1.02
1.2
1.1
—
—
—
0
0
34
462
0.73
1.01
1.4
1.5
—
—
—
0
0
41
307
1.34
1.01
2.5
1.7
—
—
—
0
0
9
48
1.88
1.00
1.7
1.5
—
—
—
0
0
369
3377
1.10
1.00
4.1
3.6
1.4
2.0
mmol/l
2.67
273
2519
38
282
1.35
1.00
1.2
1.3
1.0
1.1
promille
0.19
32
213
20
131
1.53
0.99
1.2
1.0
—
—
—
0
0
13
76
1.71
0.98
1.1
1.2
88.1
126.4
ug/l
—
8
46
15
93
1.61
0.93
1.6
1.6
—
—
—
0
0
28
200
1.40
0.93
1.1
1.2
—
—
—
0
0
10
55
1.82
0.92
1.3
1.5
—
—
—
0
0
99
836
1.19
0.91
2.4
1.4
0.7
0.8
nmol/l
0.77
75
689
6
29
2.07
0.89
1.2
1.0
—
—
—
0
0
8
42
1.91
0.88
1.0
1.0
—
—
—
0
0
1091
10444
1.06
0.88
4.9
4.5
1.0
1.0
kg/l
0.72
151
1606
31
228
1.36
0.88
1.0
1.0
—
—
—
0
0
48
604
0.79
0.85
3.8
3.5
65.5
58.3
%
1.30
24
382
15
96
1.56
0.84
5.1
4.0
33.8
38.2
u/l
—
6
30
21
146
1.44
0.82
1.1
1.2
—
—
—
0
0
25
180
1.39
0.81
1.2
1.1
1.0
1.1
ratio
—
9
54
43
542
0.79
0.79
1.3
1.3
7688.5
128503.2
e6/l
4.24
33
363
17
114
1.49
0.79
1.1
1.3
—
—
—
0
0
19
131
1.45
0.78
1.8
1.5
10.7
9.6
ug/l
0.38
19
131
61
503
1.22
0.76
1.3
1.2
—
—
—
0
0
108
937
1.16
0.76
1.3
1.3
4.1
3.8
mmol/l
1.13
101
876
15
99
1.52
0.75
1.0
1.2
64.1
83.7
%
—
7
48
395
3682
1.08
0.75
7.0
6.8
24.5
24.7
mmol/l
0.56
369
3412
33
253
1.31
0.74
1.2
1.3
—
—
—
0
0
30
227
1.32
0.74
1.1
1.1
320.8
284.8
mg/l
0.38
23
202
84
982
0.85
0.74
3.2
3.5
1.2
1.6
%
0.87
60
740
27
202
1.34
0.72
1.2
1.2
46.8
64.2
%
—
5
29
9
56
1.61
0.72
1.0
1.0
—
—
—
0
0
33
255
1.30
0.71
1.2
1.3
—
—
—
0
0
19
134
1.42
0.71
1.2
1.1
—
15.9
—
0
18
42
522
0.80
0.71
1.4
1.5
26.2
28.4
%
0.14
24
319
67
794
0.84
0.70
1.1
1.1
—
—
—
0
0
109
954
1.15
0.70
1.5
1.4
—
—
—
0
0
380
3550
1.08
0.69
4.2
3.6
5.1
5.2
kpa
0.69
347
3270
15
216
0.69
0.68
1.2
1.9
—
—
—
0
0
39
311
1.26
0.67
4.1
3.6
—
—
—
0
0
31
240
1.29
0.67
1.1
1.1
51.0
41.0
mg/l
0.51
23
209
5
91
0.55
0.67
1.0
1.3
—
—
—
0
0
72
613
1.18
0.66
1.3
1.3
297.7
268.7
pmol/l
0.27
58
465
15
214
0.70
0.66
1.1
1.8
—
—
—
0
0
15
214
0.70
0.66
1.1
1.8
—
—
—
0
0
652
6832
0.95
0.64
5.4
4.9
33.4
33.2
%
0.11
412
4403
5
29
1.72
0.64
1.4
1.4
—
—
—
0
0
43
350
1.23
0.63
4.9
5.1
19.0
87.4
u/ml
2.46
17
100
28
216
1.30
0.63
1.1
1.1
—
—
—
0
0
64
543
1.18
0.62
1.4
1.5
—
—
—
0
0
54
451
1.20
0.62
1.3
1.6
19.5
23.8
u/ml
0.35
12
91
20
268
0.75
0.61
1.6
1.4
3.2
3.5
%
—
6
62
200
2181
0.91
0.61
4.4
4.3
45.4
70.5
u/ml
1.12
191
2087
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
35
281
1.25
0.59
2.1
1.5
—
—
—
0
0
35
281
1.25
0.59
2.1
1.5
—
—
—
0
0
232
2144
1.09
0.59
3.3
3.4
117.4
1973.2
u/ml
2.23
195
1817
8
54
1.48
0.57
1.1
1.2
—
—
—
0
0
22
167
1.32
0.56
1.0
1.2
—
—
—
0
0
24
185
1.30
0.56
1.2
1.1
—
—
—
0
0
109
974
1.12
0.55
1.3
1.3
—
—
—
0
0
248
2308
1.08
0.54
1.9
1.9
—
—
—
0
0
9
60
1.50
0.54
1.0
1.1
—
—
—
0
0
43
358
1.20
0.53
1.0
1.1
0.6
1.9
u/ml
1.28
24
140
121
1091
1.11
0.53
1.4
1.3
544.7
544.7
mg/l
0.00
115
1026
85
750
1.14
0.53
1.5
2.2
32.5
27.3
mg/l
0.21
14
175
235
2187
1.08
0.52
4.3
4.0
24.5
25.0
mmol/l
1.76
212
1994
17
126
1.35
0.51
2.6
2.5
—
—
—
0
0
202
1871
1.08
0.51
1.9
1.8
—
—
—
0
0
661
6363
1.04
0.48
3.9
4.1
11.4
24.8
ug/l
2.05
543
5285
228
2129
1.07
0.48
1.8
1.8
—
—
—
0
0
21
267
0.79
0.47
2.8
3.5
—
—
—
0
0
7
47
1.49
0.47
1.3
1.7
—
—
—
0
0
25
200
1.25
0.46
1.0
1.1
1.6
1.4
u/ml
0.07
11
82
8
117
0.68
0.45
1.0
1.1
—
—
—
0
0
17
129
1.32
0.45
1.8
2.2
6.8
7.6
mmol/l
—
10
83
26
210
1.24
0.45
1.7
1.5
0.2
0.2
nmol/l
0.25
16
145
22
275
0.80
0.44
1.3
1.3
0.5
0.9
u/ml
—
10
143
31
373
0.83
0.44
1.4
1.5
—
—
—
0
0
355
3375
1.06
0.44
4.4
3.2
126.2
127.8
g/l
0.67
346
3280
13
95
1.37
0.43
1.6
1.6
123.5
113.3
ug/l
—
8
82
8
56
1.43
0.42
2.0
2.3
0.4
0.5
u/field
—
8
56
257
2723
0.94
0.42
4.9
3.3
25.0
25.2
mmol/l
0.64
252
2639
20
158
1.27
0.41
1.2
1.2
—
—
—
0
0
20
158
1.27
0.41
1.3
2.0
17.0
52.9
u/l
1.43
20
143
0
15
0.00
0.41
0.0
1.1
—
1.0
—
0
9
257
2428
1.06
0.40
2.0
1.9
5.4
2.2
ug/l
0.82
213
2123
5
34
1.47
0.40
1.8
1.4
—
—
—
0
0
24
195
1.23
0.40
1.3
1.3
—
—
—
0
0
23
186
1.24
0.40
1.3
1.2
188.7
381.5
ug/l
0.33
11
99
5
35
1.43
0.39
1.2
1.3
—
—
—
0
0
5
35
1.43
0.39
1.0
1.2
—
—
—
0
0
70
626
1.12
0.39
6.0
5.6
7.6
7.3
mmol/l
0.30
58
516
7
106
0.66
0.39
1.1
1.2
—
—
—
0
0
61
686
0.89
0.39
1.4
1.5
53.8
63.0
%
0.99
41
413
16
124
1.29
0.38
1.2
1.1
—
—
—
0
0
5
36
1.39
0.38
1.2
1.3
—
—
—
0
0
52
458
1.14
0.37
1.1
1.1
—
—
—
0
0
39
336
1.16
0.37
1.5
2.0
15.9
14.5
%
0.26
16
128
8
115
0.70
0.37
1.8
1.4
—
—
—
0
0
52
460
1.13
0.35
1.1
1.6
—
—
—
0
0
52
460
1.13
0.35
1.1
1.6
—
—
—
0
0
52
460
1.13
0.35
1.1
1.6
—
—
—
0
0
13
99
1.31
0.35
1.2
1.1
—
—
—
0
0
30
254
1.18
0.35
2.7
2.6
30.0
37.1
%
—
9
104
19
153
1.24
0.35
1.0
1.1
—
—
—
0
0
45
510
0.88
0.34
1.2
1.6
—
—
—
0
0
6
45
1.33
0.33
1.0
1.2
5.2
12.0
u/l
—
6
45
154
1444
1.07
0.33
3.6
3.0
24.9
25.0
mmol/l
0.17
137
1260
17
137
1.24
0.32
21.5
7.5
—
—
—
0
0
55
609
0.90
0.29
1.3
1.5
—
—
—
0
0
63
573
1.10
0.29
1.0
1.1
—
—
—
0
0
17
139
1.22
0.29
1.1
1.6
0.3
0.4
ug/l
—
9
82
14
112
1.25
0.28
1.0
2.1
188.1
211.0
%
0.55
14
105
8
63
1.27
0.27
1.6
1.5
—
—
—
0
0
141
1494
0.94
0.27
1.5
1.4
—
—
—
0
0
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
8
64
1.25
0.27
1.0
1.3
—
82.6
—
0
21
23
196
1.17
0.27
1.7
1.4
1.9
25.2
u/l
—
8
68
81
750
1.08
0.26
1.3
1.4
—
—
—
0
0
135
1274
1.06
0.26
1.3
1.3
—
—
—
0
0
36
405
0.89
0.26
1.0
1.1
—
3.3
—
0
7
23
267
0.86
0.25
1.1
1.7
—
—
—
0
0
23
267
0.86
0.25
1.1
1.7
—
—
—
0
0
23
267
0.86
0.25
1.1
1.7
—
—
—
0
0
23
267
0.86
0.25
1.1
1.7
—
—
—
0
0
9
72
1.25
0.25
1.0
1.2
—
—
—
0
0
29
330
0.88
0.25
1.4
1.5
—
—
—
0
0
49
539
0.91
0.25
1.2
1.6
—
—
—
0
0
29
255
1.14
0.24
2.1
1.8
2.9
2.5
u/field
0.10
21
173
13
106
1.23
0.23
1.0
1.1
—
—
—
0
0
31
275
1.13
0.23
2.3
2.3
—
—
—
0
0
32
285
1.12
0.22
1.4
1.5
13.4
14.1
umol/l
0.19
27
266
71
763
0.93
0.22
1.3
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.6
—
0
6
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
2.3
—
0
10
55
507
1.09
0.21
1.2
1.2
64.6
191.9
miu/ml
—
10
157
18
154
1.17
0.21
1.0
1.1
—
—
—
0
0
36
325
1.11
0.21
1.1
1.1
—
—
—
0
0
23
202
1.14
0.20
1.1
1.3
—
—
—
0
0
6
50
1.20
0.19
1.0
1.0
—
—
—
0
0
96
908
1.06
0.19
1.3
1.3
37.5
37.6
u/l
0.00
87
800
39
426
0.91
0.18
1.0
1.0
36.8
44.2
ng/l
0.80
27
269
39
426
0.91
0.18
1.0
1.0
740.3
691.7
ng/l
0.39
28
267
39
426
0.91
0.18
1.0
1.0
326.8
332.1
ng/l
0.05
28
275
30
332
0.90
0.18
1.4
1.5
—
—
—
0
0
7
58
1.21
0.18
1.1
1.2
—
—
—
0
0
14
119
1.18
0.17
1.3
1.9
1.9
2.1
ug/l
—
8
61
132
1265
1.04
0.17
1.2
1.5
—
—
—
0
0
93
883
1.05
0.17
1.6
1.6
—
—
—
0
0
7
62
1.13
0.17
1.0
1.2
7.5
154910.9
nmol/l
—
7
51
98
933
1.05
0.17
1.3
1.4
—
—
—
0
0
17
148
1.15
0.16
1.2
1.1
—
—
—
0
0
20
177
1.13
0.16
1.3
1.0
1.1
1.1
u/l
—
9
90
11
92
1.20
0.16
1.8
1.8
—
—
—
0
0
49
457
1.07
0.16
1.5
1.3
—
—
—
0
0
27
246
1.10
0.14
1.5
1.3
—
—
—
0
0
43
401
1.07
0.14
1.1
1.4
—
—
—
0
0
8
97
0.82
0.13
1.0
1.2
—
—
—
0
0
8
99
0.81
0.13
1.1
1.3
117.9
114.4
%
—
8
84
26
284
0.92
0.13
1.0
1.2
12.6
12.2
mmol/l
0.14
12
86
22
199
1.11
0.13
6.8
4.0
31.5
66.6
u/ml
—
6
26
38
354
1.07
0.13
1.5
1.4
—
—
—
0
0
42
394
1.07
0.12
1.1
1.1
3.6
2.1
u/ml
0.42
14
103
60
571
1.05
0.12
5.0
4.4
338.0
347.6
umol/l
0.19
48
487
12
105
1.14
0.11
1.4
1.8
—
—
—
0
0
10
115
0.87
0.10
1.8
2.5
—
—
—
0
0
21
193
1.09
0.10
1.5
1.2
3.1
3.5
mmol/l
0.33
21
170
5
46
1.09
0.09
4.6
5.2
—
—
—
0
0
135
1316
1.03
0.09
5.7
6.7
104.6
105.2
mmol/l
0.87
123
1169
5
63
0.79
0.08
2.2
2.1
—
—
—
0
0
118
1152
1.02
0.08
1.3
1.4
—
—
—
0
0
41
392
1.05
0.07
1.1
1.4
—
—
—
0
0
42
438
0.96
0.07
1.5
1.5
—
—
—
0
0
17
157
1.08
0.07
1.0
1.0
0.0
0.3
u/ml
—
6
58
86
839
1.03
0.06
1.3
1.4
—
—
—
0
0
94
962
0.98
0.06
1.1
1.1
13.7
5.5
u/ml
—
7
57
285
2882
0.99
0.06
2.5
2.9
0.2
0.3
e6/l
2.24
277
2831
37
385
0.96
0.05
1.0
1.1
—
56.5
—
0
7
19
178
1.07
0.05
1.7
2.1
4227.0
23469.0
e6/l
1.05
11
103
29
277
1.05
0.05
1.6
1.4
—
—
—
0
0
93
949
0.98
0.05
1.2
1.6
—
—
—
0
0
70
683
1.03
0.05
1.3
1.4
—
—
—
0
0
28
292
0.96
0.04
1.1
1.5
—
—
—
0
0
28
292
0.96
0.04
1.1
1.5
—
—
—
0
0
12
111
1.08
0.04
1.4
1.2
1.8
1.6
mmol/l
—
6
70
68
694
0.98
0.04
1.4
1.4
—
—
—
0
0
74
753
0.98
0.03
1.2
1.5
—
—
—
0
0
10
92
1.09
0.03
1.0
1.6
—
13.7
—
0
5
24
231
1.04
0.02
1.2
1.1
—
—
—
0
0
69
679
1.02
0.02
1.4
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
23
238
0.97
0.02
1.2
1.1
—
—
—
0
0
42
412
1.02
0.01
2.6
2.0
2.5
2.0
u/field
0.17
16
148
69
683
1.01
0.01
1.4
1.4
—
—
—
0
0
244
2448
1.00
0.01
4.8
5.0
1.6
1.6
%
0.37
227
2282
18
174
1.03
0.00
1.6
1.8
—
—
—
0
0
16
165
0.97
0.00
2.8
2.2
—
—
—
0
0
16
165
0.97
0.00
2.7
2.2
—
—
—
0
0
39
388
1.01
0.00
1.3
1.2
32.0
41.2
u/ml
—
5
33
123
1232
1.00
0.00
1.2
1.6
—
—
—
0
0
68
685
0.99
0.00
1.4
1.4
—
—
—
0
0
15
146
1.03
0.00
1.4
2.1
25.5
31.5
%
1.19
15
131
241
2415
1.00
0.00
4.9
5.1
0.9
0.9
%
0.74
223
2254
33
334
0.99
0.00
1.6
1.9
—
—
—
0
0
20
197
1.02
0.00
1.8
2.2
542.4
7161.4
e6/l
0.81
13
137
68
683
1.00
0.00
1.4
1.4
—
—
—
0
0
11
111
0.99
0.00
1.7
1.5
265.8
130.8
ng/l
0.60
11
111
15
149
1.01
0.00
1.0
1.2
—
—
—
0
0
70
701
1.00
0.00
1.4
1.4
—
—
—
0
0
5
54
0.93
0.00
1.0
1.6
39.8
40.6
umol/l
—
5
54
6
63
0.95
0.00
2.0
2.1
—
—
—
0
0
126
1260
1.00
0.00
3.5
3.2
49.1
826.9
u/ml
2.68
115
1150
9
89
1.01
0.00
1.2
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
13
130
1.00
0.00
1.1
1.0
106.1
90.0
%
—
8
91
6
61
0.98
0.00
1.0
1.1
—
—
—
0
0
10
100
1.00
0.00
1.9
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint MACULAR_PUCKER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| MACULAR_PUCKER | 0.774 [0.65, 0.93] | 0.005 |
| Birth year | 0.995 [0.99, 1.0] | 0.204 |
During the follow-up period (1.1.1998 — 31.12.2019), 810 out of 10656 females with MACULAR_PUCKER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| MACULAR_PUCKER | 0.757 [0.63, 0.92] | 0.004 |
| Birth year | 0.986 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 1119 out of 9856 males with MACULAR_PUCKER died.
Mortality risk
Mortality risk for people of age
years, who have MACULAR_PUCKER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.09% | 0.136% |
| 5 | 0.482% | 0.823% |
| 10 | 1.155% | 2.18% |
| 15 | 2.192% | 3.949% |
| 20 | 3.793% | 6.763% |
Relationships between endpoints
↥Index endpoint: MACULAR_PUCKER – Macular pucker
GWS hits: 12
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data