Macular pucker

MACULAR_PUCKER

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H35.38#
  • Hospital discharge: ICD-9 3625F
  • Cause of death: ICD-10 H35.38#
  • Cause of death: ICD-9 3625F

2 out of 7 registries used, show all original rules.

6223

4. Check minimum number of events

None

6223

5. Include endpoints

None

6223

6. Filter based on genotype QC (FinnGen only)

6055

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H35

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 27005 13935 13051
Only index persons 26829 13856 12973
Unadjusted period prevalence (%)
Whole population 0.38 0.40 0.36
Only index persons 0.50 0.51 0.50
Median age at first event (years)
Whole population 71.79 71.14 72.47
Only index persons 71.79 71.14 72.48

-FinnGen-

Key figures

All Female Male
Number of individuals 6055 3017 3038
Unadjusted period prevalence (%) 1.23 1.07 1.39
Median age at first event (years) 71.62 70.19 73.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
6223
Matched controls
62230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H35.36
ICD-10 Finland
Macular cyst
1692.3
323.3
312
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
5.6
307.7
1409
3091
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
97.7
307.7
495
55
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.1
307.7
1971
6389
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
488.7
307.7
536
12
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
4.3
307.7
3871
17294
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
4.1
307.7
3663
16122
H33.3
ICD-10 Finland
Retinal breaks without detachment
382.9
307.7
428
12
H33.0
ICD-10 Finland
Retinal detachment with retinal break
1043.3
307.7
482
5
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
196.1
307.7
833
49
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
4707.8
307.7
1188
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
17.3
307.7
2417
2208
H25.1
ICD-10 Finland
Senile nuclear cataract
3.7
307.7
3325
14592
Z96.1
ICD-10 Finland
Presence of intraocular lens
7.2
307.7
2517
5334
H34.8
ICD-10 Finland
Other retinal vascular occlusions
92.3
307.7
214
24
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
351.1
307.7
1051
36
H35.37
ICD-10 Finland
Macular holes
859.1
307.7
477
6
CKD40
NOMESCO Finland
Endophotocoagulation of retina
690.5
307.7
328
5
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
10.7
307.7
1225
1397
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
247.7
307.7
892
42
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
119.7
307.7
893
87
XCH00
NOMESCO Finland
Eye pressure measurement
5.7
307.7
659
1261
XCD20
NOMESCO Finland
Photoangiography of eye
42.4
307.7
197
48
XCW99
NOMESCO Finland
Other investigative procedure of eye
10.9
307.7
2166
2915
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
152.3
307.7
318
22
XCK10
NOMESCO Finland
Photography of fundus of eye
4.4
307.7
1149
3025
WX140
NOMESCO Finland
Parabulbar anesthesy
51.0
307.7
2137
632
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
25.3
307.7
725
323
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
4503599627370496.0
307.7
6216
107
H26.4
ICD-10 Finland
After-cataract
5.6
307.7
1680
3838
CKC12
NOMESCO Finland
Photocoagulation of retina
105.3
307.7
651
69
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
436.6
307.7
865
23
ZXA10
NOMESCO Finland
Bilateral
3.0
302.6
1857
7829
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
129.2
275.3
139
11
WX002
NOMESCO Finland
Sedation and analgesia
2.8
274.6
1940
8747
H36.01
ICD-10 Finland
Diabetic maculopathy
127.3
271.0
137
11
H43.1
ICD-10 Finland
Vitreous haemorrhage
11.3
264.3
281
259
WX142
NOMESCO Finland
Sub-tenon anesthesy
24.4
262.9
187
79
CKC10
NOMESCO Finland
Local photocoagulation of retina
57.5
259.9
146
26
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.9
257.2
1483
5979
S01ED51
ATC
timolol, combinations; ophthalmic
3.5
225.8
885
2825
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
198.9
3344
21448
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
69.8
189.4
103
15
H3601, E113,
ICD-10 Finland
+∞
182.2
174
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
34.4
181.7
115
34
ZXA05
NOMESCO Finland
Left side
2.3
181.7
2093
11436
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
70.4
178.6
97
14
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.9
174.7
918
3459
ZXA00
NOMESCO Finland
Right side
2.2
174.2
2218
12572
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
12.8
157.5
153
122
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
18.2
153.0
123
69
H25.0
ICD-10 Finland
Senile incipient cataract
3.0
147.9
723
2605
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
9.9
147.0
170
176
H26.2
ICD-10 Finland
Complicated cataract
9.4
141.6
170
185
H3600, E113,
ICD-10 Finland
+∞
139.1
133
*
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
58.4
133.7
75
13
XCK00
NOMESCO Finland
Perimetry
3.1
130.5
607
2120
ZXE00
NOMESCO Finland
One hour or less
1.9
121.9
2629
17417
CKC15
NOMESCO Finland
Panretinal photocoagulation
60.6
118.4
66
11
H35.8
ICD-10 Finland
Other specified retinal disorders
236.4
113.1
116
5
H3603, E113,
ICD-10 Finland
+∞
103.4
99
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
207.4
98.7
102
5
S01EA03
ATC
apraclonidine; ophthalmic
8.8
97.3
123
143
114
Kela drug reimbursment
Glaucoma
2.3
95.5
795
3686
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
31.3
95.1
62
20
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
4.6
93.1
229
518
A10AA01, ,
ATC
7.3
93.0
137
191
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.6
92.6
224
500
H40.0
ICD-10 Finland
Glaucoma suspect
2.4
90.8
693
3089
A98
ICPC
Health maint/preventive medicine
4.5
90.1
6061
55609
H33.5
ICD-10 Finland
Other retinal detachments
13.8
89.5
83
61
A10AA02, ,
ATC
5.4
88.0
176
334
H35.9
ICD-10 Finland
Retinal disorder, unspecified
34.7
86.9
55
16
H20.1
ICD-10 Finland
Chronic iridocyclitis
8.1
86.0
116
146
H53.1
ICD-10 Finland
Subjective visual disturbances
2.7
85.9
516
2053
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
428.5
85.3
85
*
Z2221
NOMESCO Finland
Medical doctor
1.8
85.1
1785
11434
H25.8
ICD-10 Finland
Other senile cataract
2.1
84.4
968
5082
XCW10
NOMESCO Finland
Assessment of vision
6.1
83.9
147
246
S01EC04
ATC
brinzolamide; ophthalmic
3.0
83.5
396
1390
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.4
83.3
307
927
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
82.9
2447
17211
A10AB01
ATC
insulin (human); parenteral
4.9
82.8
183
379
S01BC03
ATC
diclofenac; ophthalmic
4.6
81.1
196
437
A10AB04
ATC
insulin lispro; parenteral
4.8
76.7
177
380
Z3231
NOMESCO Finland
Registered nurse
1.7
76.5
1858
12335
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.5
75.2
489
2018
S01EE01
ATC
latanoprost; ophthalmic
2.4
73.4
553
2442
T89
ICPC
Diabetes insulin dependent
3.9
73.3
218
569
H3603, E103,
ICD-10 Finland
+∞
72.0
69
*
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
10.0
71.1
81
82
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.6
69.7
434
1753
H35.4
ICD-10 Finland
Peripheral retinal degeneration
145.7
68.0
72
5
H52.1
ICD-10 Finland
Myopia
4.2
66.7
179
433
S01ED01
ATC
timolol; ophthalmic
3.0
66.7
301
1026
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
66.5
2490
18305
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.1
65.9
291
979
H3601, E103,
ICD-10 Finland
+∞
64.7
62
*
S01EA05
ATC
brimonidine; ophthalmic
3.5
64.2
231
686
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
62.6
60
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
11.5
62.0
64
56
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
212.1
61.2
63
*
ZX198
NOMESCO Finland
Other local administration
8.7
60.6
77
90
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
4.7
60.4
139
298
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
11.8
60.1
61
52
CKC20
NOMESCO Finland
Cryopexy of undetached retina
127.3
58.9
63
5
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.7
58.6
192
536
H3600, E103,
ICD-10 Finland
+∞
58.4
56
*
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
201.9
58.1
60
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
56.4
587
2948
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.9
55.8
266
934
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
55.3
53
*
H35.7
ICD-10 Finland
Separation of retinal layers
284.1
55.3
56
*
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.3
53.4
206
639
S01BC05
ATC
ketorolac; ophthalmic
2.8
52.3
276
1024
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
7.2
49.9
74
104
CKD20
NOMESCO Finland
Removal of vitreous body substitute
252.2
49.1
50
*
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
7.1
49.1
74
106
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
171.4
48.9
51
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
48.5
4033
34269
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
102.9
46.8
51
5
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.8
46.4
141
374
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
461.3
46.3
46
*
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
44.6
692
3970
CS494
NOMESCO Finland
Other visual field testing
2.9
44.4
208
723
A10AB05
ATC
insulin aspart; parenteral
2.1
44.1
448
2223
S01EC01
ATC
acetazolamide; systemic
3.5
43.7
151
437
A10AC01
ATC
insulin (human); parenteral
2.2
43.0
391
1859
H35.6
ICD-10 Finland
Retinal haemorrhage
94.8
42.8
47
5
H43.3
ICD-10 Finland
Other vitreous opacities
4.0
42.7
120
301
H40.11
ICD-10 Finland
Low pressure glaucoma
2.9
42.5
199
692
CKD15
NOMESCO Finland
Injection of vitreous substitute
216.5
41.9
43
*
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
8.1
41.8
56
70
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
2.4
41.7
289
1224
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
7.7
41.6
58
76
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
4.2
40.8
108
259
S01EE05
ATC
tafluprost; ophthalmic
2.4
40.7
303
1325
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.9
40.4
73
126
A10AE04
ATC
insulin glargine; parenteral
1.9
40.2
580
3248
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.4
40.1
286
1227
1LA05, ,
NOMESCO Finland
+∞
39.6
38
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
3.6
39.6
129
359
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
5.2
39.1
80
155
H30.2
ICD-10 Finland
Posterior cyclitis
390.0
39.1
39
*
F29
ICPC
Eye symptom/complaint other
1.8
37.8
574
3264
S18
ICPC
Laceration/cut
1.4
37.2
2985
24619
H26.02
ICD-10 Finland
Presenil cataract
2.8
35.8
186
684
H04AA01
ATC
glucagon; nasal, parenteral
5.3
35.5
71
135
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
57.5
34.2
40
7
N02BE01
ATC
paracetamol; systemic, rectal
1.6
34.1
5464
50729
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
2.6
32.4
190
744
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
8.7
31.9
40
46
S01EE03
ATC
bimatoprost; ophthalmic
2.6
31.8
190
751
E10
ICD-10 Finland
Type 1 diabetes mellitus
4.7
31.7
72
153
Z71.8
ICD-10 Finland
Other specified counselling
1.4
31.5
1615
12218
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
7.8
30.6
42
54
H57.1
ICD-10 Finland
Ocular pain
2.5
30.3
190
769
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
11.1
30.2
32
29
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
2.7
30.1
160
596
H36.02
ICD-10 Finland
Preproliferative diabetic retinopathy
+∞
29.2
28
*
H3602, E113,
ICD-10 Finland
+∞
29.2
28
*
F38
ICPC
Eye, Other laboratory test NEC
3.2
29.0
118
379
R4110
NOMESCO Finland
Physiotherapy
1.4
27.6
1675
12998
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
2.4
27.3
185
776
A10AA03, ,
ATC
7.9
27.2
37
47
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.7
26.8
61
130
H33.4
ICD-10 Finland
Traction detachment of retina
272.3
26.7
27
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.9
26.5
325
1721
XCH05
NOMESCO Finland
Eye pressure longterm registration
3.7
26.5
84
230
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
3.0
26.4
120
411
F05
ICPC
Visual disturbance other
2.3
26.4
194
844
S01EE04
ATC
travoprost; ophthalmic
2.6
26.3
158
627
H27.1
ICD-10 Finland
Dislocation of lens
6.0
25.9
45
75
H20.8
ICD-10 Finland
Other iridocyclitis
6.4
25.6
42
66
H53.8
ICD-10 Finland
Other visual disturbances
3.3
25.3
95
291
H34.2
ICD-10 Finland
Other retinal artery occlusions
50.2
25.2
30
6
H44.0
ICD-10 Finland
Purulent endophthalmitis
35.7
25.2
32
9
A10AE05
ATC
insulin detemir; parenteral
2.0
25.1
275
1401
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
8.9
25.0
31
35
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
25.0
24
*
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
58.3
25.0
29
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
24.8
3015
25879
F43
ICPC
Eye, Other diagnostic procedure
2.6
24.7
143
557
H34.1
ICD-10 Finland
Central retinal artery occlusion
48.5
24.3
29
6
SDA03
NOMESCO Finland
Periodontal treatment
1.3
24.1
1985
16093
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
3.4
24.0
84
246
177
Kela drug reimbursment
Insulin glargine 300 U / ml
3.0
23.6
106
361
CKA10
NOMESCO Finland
Biopsy of vitreous body
26.8
23.5
32
12
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
23.4
1513
11803
Z5132
NOMESCO Finland
Nursing associate professional
6.0
23.4
41
69
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
5.7
23.3
43
76
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
6.1
23.2
40
66
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
8.4
23.1
30
36
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
23.1
3354
29378
A02BC02
ATC
pantoprazole; systemic
1.3
23.0
4109
37017
J01DB01
ATC
cefalexin; oral
1.4
22.9
4772
43962
R42
ICD-10 Finland
Dizziness and giddiness
1.4
22.6
1411
10936
ZXD20
NOMESCO Finland
Day surgery
1.5
22.5
680
4601
H40.9
ICD-10 Finland
Glaucoma, unspecified
2.6
22.5
132
518
C10AA05
ATC
atorvastatin; oral
1.3
22.3
2846
24451
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
22.3
3722
33142
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.5
22.2
697
4754
M79.6
ICD-10 Finland
Pain in limb
1.3
22.2
2305
19252
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
3.8
22.0
67
179
CKD50
NOMESCO Finland
Endodiathermy of retina
+∞
21.9
21
*
L17
ICPC
Foot/toe symptom/complaint
1.3
21.7
1699
13623
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
5.2
21.7
44
85
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
2.2
21.6
190
892
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
8.3
21.4
28
34
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
21.1
1226
9382
A10AE06
ATC
insulin degludec; parenteral
2.3
21.0
158
695
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
8.5
21.0
27
32
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
8.5
21.0
27
32
A10AD01
ATC
insulin (human); parenteral
3.5
20.8
70
200
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
20.6
1511
11982
E0000UV, ,
ATC
1.3
20.5
2221
18607
Z01.2
ICD-10 Finland
Dental examination
1.3
20.5
2242
18808
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
7.8
20.4
28
36
H43.2
ICD-10 Finland
Crystalline deposits in vitreous body
6.4
20.1
33
52
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
19.9
2278
19201
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
19.8
19
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
19.2
1552
12461
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.4
19.2
1091
8301
H33
ICD-10 Finland
Retinal detachments and breaks
26.1
19.1
26
10
L03
ICPC
Low back symptom/complaint
1.3
19.0
1439
11444
H54.7
ICD-10 Finland
Unspecified visual loss
4.2
18.8
49
117
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
18.5
2848
24831
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
18.2
2235
18945
H33.2
ICD-10 Finland
Serous retinal detachment
52.7
17.9
21
*
S01GX01
ATC
cromoglicic acid; ophthalmic
1.4
17.8
865
6405
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
17.7
17
*
WX320
NOMESCO Finland
Spinalanesthesy
1.3
17.6
1486
11979
N17
ICPC
Vertigo/dizziness
1.4
17.2
737
5337
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
17.0
1688
13896
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.6
16.8
459
3033
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
16.6
2208
18845
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.4
16.5
952
7245
S01EC03
ATC
dorzolamide; ophthalmic
2.6
16.5
94
365
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
1.9
16.4
222
1216
XKD00
NOMESCO Finland
Uroflowmetry
1.3
16.2
1107
8644
L01
ICPC
Neck symptom/complaint
1.4
16.1
759
5584
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
24.5
16.0
22
9
R01AD09
ATC
mometasone; nasal
1.3
16.0
2152
18370
C10AA07
ATC
rosuvastatin; oral
1.3
15.9
1945
16414
H02.3
ICD-10 Finland
Blepharochalasis
1.6
15.5
409
2680
CK2X4, ,
SPAT
11.7
15.5
28
24
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.3
15.4
1132
8927
H53.2
ICD-10 Finland
Diplopia
1.9
15.4
190
1010
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
4.7
15.4
35
75
H02
ICPC
Hearing complaint
1.4
15.3
920
7046
H02.4
ICD-10 Finland
Ptosis of eyelid
1.9
15.2
180
944
S01EX03, ,
ATC
2.3
14.9
114
507
WX402
NOMESCO Finland
General anaesthesia
1.3
14.8
1068
8396
H26.9
ICD-10 Finland
Cataract, unspecified
2.2
14.8
119
540
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.3
14.8
1077
8480
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
14.7
1879
15901
H50.2
ICD-10 Finland
Vertical strabismus
3.3
14.7
55
169
CHC05
NOMESCO Finland
Iridotomy
2.3
14.7
108
472
K02.1
ICD-10 Finland
Caries of dentine
1.2
14.7
2824
25007
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
14.6
2089
17904
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
14.6
14
*
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
80.3
14.6
16
*
NHQ40
NOMESCO Finland
Amputation of toe
2.5
14.6
93
382
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
6.3
14.5
24
38
N06AX21
ATC
duloxetine; oral
1.5
14.5
532
3738
H21.0
ICD-10 Finland
Hyphaema
5.4
14.5
28
52
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
2.0
14.5
150
752
EB1AA, ,
SPAT
1.6
14.4
310
1935
R05
ICD-10 Finland
Cough
1.3
14.4
1152
9185
N02AX02
ATC
tramadol; systemic, rectal
1.2
14.4
2464
21535
H91.1
ICD-10 Finland
Presbycusis
1.5
14.3
438
2965
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.4
14.3
554
3931
A10AD04
ATC
insulin lispro; parenteral
6.2
14.2
24
39
H01.0
ICD-10 Finland
Blepharitis
1.7
14.2
274
1665
KMAK, ,
NOMESCO Finland
1.2
14.1
2410
21043
Z3226
NOMESCO Finland
Physiotherapist
1.3
14.1
990
7751
S01ED02
ATC
betaxolol; ophthalmic
3.0
14.0
61
206
C07AB07
ATC
bisoprolol; oral
1.2
13.9
3148
28295
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.4
13.9
565
4046
N03AX16
ATC
[U] pregabalin
1.3
13.8
1276
10365
R05
ICPC
Cough
1.3
13.8
1254
10166
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
3.4
13.8
49
146
AA1AD
NOMESCO Finland
CT of head and brain
1.3
13.7
1694
14257
S29
ICPC
Skin symptom/complaint other
1.3
13.6
1085
8642
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
12.0
13.6
24
20
CKC65
NOMESCO Finland
Removal of buckling implant from sclera
+∞
13.5
13
*
H3603, E107,
ICD-10 Finland
+∞
13.5
13
*
H3602, E103,
ICD-10 Finland
+∞
13.5
13
*
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
3.2
13.5
51
158
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
34.1
13.5
17
5
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
13.5
1431
11825
C08CA01
ATC
amlodipine; oral
1.2
13.4
2496
21951
G04CA02
ATC
tamsulosin; oral
1.3
13.4
1600
13406
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
13.3
1521
12674
CG2T4
NOMESCO Finland
Topography assessment of cornea
3.0
13.3
59
201
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
21.2
13.3
19
9
SFA10
NOMESCO Finland
One-surface restoration
1.2
13.3
2724
24194
SFA20
NOMESCO Finland
Two-surface restoration
1.2
13.2
2818
25124
A97
ICPC
No disease
1.3
13.1
988
7808
R06.0
ICD-10 Finland
Dyspnoea
1.3
13.0
1557
13043
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
28.4
12.9
17
6
K85
ICPC
Elevated blood pressure
1.3
12.9
1019
8101
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.2
12.9
2388
20968
H81
ICPC
Excessive ear wax
1.3
12.8
1077
8632
A11
ICPC
Chest pain NOS
1.5
12.8
482
3402
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
2.8
12.7
61
217
Z01.7
ICD-10 Finland
Laboratory examination
1.4
12.7
732
5555
M25.5
ICD-10 Finland
Pain in joint
1.3
12.7
1527
12787
H25.9
ICD-10 Finland
Senile cataract, unspecified
2.2
12.7
108
503
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
12.7
1339
11047
H16.0
ICD-10 Finland
Corneal ulcer
1.7
12.7
214
1255
C10AA01
ATC
simvastatin; oral
1.2
12.7
2907
26066
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.7
12.6
247
1507
J01FA10
ATC
azithromycin; systemic
1.2
12.5
2689
23939
H53.4
ICD-10 Finland
Visual field defects
2.1
12.5
116
558
B01AF02
ATC
apixaban; oral
1.3
12.5
859
6692
H54.5
ICD-10 Finland
Severe visual impairment, monocular
4.1
12.5
34
84
CKD60
NOMESCO Finland
Anterior vitrectomy
3.0
12.5
53
176
CL2L4
NOMESCO Finland
Wide-field fundus photography for diabetic retinopathy screening
+∞
12.5
12
*
CKD94, ,
SPAT
+∞
12.5
12
*
H40.12
ICD-10 Finland
Pigmentary glaucoma
6.2
12.5
21
34
3744
FHL
Pericardial identification surgery with coagulation (includes epi- and intrascleral indications and eg Lincoff catheter)
130.3
12.4
13
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.3
12.4
900
7068
M54.5
ICD-10 Finland
Low back pain
1.2
12.4
1728
14709
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
2.2
12.4
106
495
S82
ICPC
Naevus/mole
1.4
12.3
702
5319
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
2.4
12.3
85
363
207
Kela drug reimbursment
Chronic arrhythmias
1.3
12.3
1081
8714
M03BX02
ATC
tizanidine; oral
1.2
12.3
3112
28141
L15
ICPC
Knee symptom/complaint
1.3
12.2
1314
10858
S97
ICPC
Chronic ulcer skin
1.5
12.1
352
2357
H26.8
ICD-10 Finland
Other specified cataract
2.9
12.1
55
190
CS2P4
NOMESCO Finland
Optic nerve head imaging
2.9
12.1
57
201
L12
ICPC
Hand/finger symptom/complaint
1.3
12.1
778
6006
XF404
NOMESCO Finland
Ambulatory ECG
1.4
12.1
528
3830
J01FF01
ATC
clindamycin; systemic
1.3
12.0
1394
11616
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.2
12.0
1701
14496
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
12.0
1335
11071
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.5
12.0
405
2799
A02BC05
ATC
esomeprazole; systemic
1.2
12.0
2245
19697
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
11.9
2577
22927
S21
ICPC
Skin texture symptom/complaint
1.3
11.8
805
6263
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
5.8
11.8
21
36
G47.3
ICD-10 Finland
Sleep apnoea
1.3
11.8
1148
9369
H50.52
ICD-10 Finland
Exophoria
3.0
11.7
50
167
C10AX09
ATC
ezetimibe; oral
1.3
11.7
953
7602
H54.3
ICD-10 Finland
Mild or no visual impairment, binocular
5.5
11.6
22
40
H53
ICD-10 Finland
Visual disturbances
3.3
11.6
42
127
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
11.5
1781
15305
R51.80
ICD-10 Finland
Headache
1.4
11.4
629
4739
H54.6
ICD-10 Finland
Moderate visual impairment, monocular
4.8
11.4
25
52
L08
ICPC
Shoulder symptom/complaint
1.3
11.4
1177
9673
F99
ICPC
Eye/adnexa disease other
3.0
11.3
47
155
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
2.4
11.2
73
304
H18.8
ICD-10 Finland
Other specified disorders of cornea
3.6
11.1
36
101
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.4
11.1
467
3362
WX144
NOMESCO Finland
Subconjunctival anesthesy
2.4
11.1
72
299
H18.4
ICD-10 Finland
Corneal degeneration
3.4
11.1
38
111
X59
ICD-10 Finland
Exposure to unspecified factor
1.3
11.1
907
7235
R4120
NOMESCO Finland
Occupational therapy
1.5
11.1
325
2183
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
11.1
1747
15036
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.3
11.0
1129
9262
-1, ,
NOMESCO Finland
1.2
10.9
1436
12117
M01AH05
ATC
etoricoxib; oral
1.2
10.9
3189
29088
U02
ICPC
Urinary frequency/urgency
1.3
10.9
754
5880
F28
ICPC
Limited function/disability (F)
3.2
10.8
42
133
D01AE16
ATC
amorolfine; topical
1.3
10.8
662
5071
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
8.2
10.8
23
28
H44.2
ICD-10 Finland
Degenerative myopia
10.6
10.7
20
19
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.3
10.7
628
4777
H47.3
ICD-10 Finland
Other disorders of optic disc
4.4
10.7
26
59
S02.51
ICD-10 Finland
Fracture of tooth, open
1.4
10.6
442
3178
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.4
10.6
430
3078
A04
ICPC
Weakness/tiredness general
1.3
10.6
731
5697
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
10.6
1042
8506
D19
ICPC
Teeth/gum symptom/complaint
1.3
10.5
1240
10331
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.3
10.5
1125
9269
-44
ICPC
Preventive immunization/medic
1.4
10.5
488
3575
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
10.5
2106
18532
WX213
NOMESCO Finland
Lower leg blockade
2.9
10.5
48
167
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.5
10.5
323
2191
H13
ICPC
Plugged feeling ear
1.3
10.5
1174
9727
S01BA01
ATC
dexamethasone; ophthalmic
1.7
10.5
169
980
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.2
10.4
1511
12873
CKD91, ,
SPAT
+∞
10.4
10
*
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
10.4
10
*
H3601, E116,
ICD-10 Finland
+∞
10.4
10
*
H3601, E119,
ICD-10 Finland
+∞
10.4
10
*
U07
ICPC
Urine symptom/complaint other
1.4
10.3
424
3041
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
10.3
3999
37324
H61.2
ICD-10 Finland
Impacted cerumen
1.5
10.3
362
2522
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
10.3
2225
19711
H43.9
ICD-10 Finland
Disorder of vitreous body, unspecified
2.8
10.3
51
186
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
1.2
10.2
1189
9891
D22
ICD-10 Finland
Melanocytic naevi
1.7
10.1
177
1050
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.3
10.1
658
5082
K80
ICPC
Cardiac arrhythmia NOS
1.4
10.1
470
3445
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
2.5
10.0
61
247
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.3
10.0
981
8001
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.3
9.9
853
6845
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.3
9.9
710
5561
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.2
9.9
1223
10241
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
16.7
9.9
15
9
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.4
9.8
515
3849
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.3
9.8
782
6209
R01AD08
ATC
fluticasone; nasal
1.2
9.8
1278
10761
R03AC02
ATC
salbutamol; inhalant
1.2
9.8
2758
24982
M86.6
ICD-10 Finland
Other chronic osteomyelitis
4.0
9.8
27
68
M01AB05
ATC
diclofenac; systemic, rectal
1.2
9.7
3525
32610
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.3
9.7
935
7608
H91.9
ICD-10 Finland
Hearing loss, unspecified
1.5
9.7
272
1812
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.2
9.6
1146
9549
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
1.6
9.6
191
1172
PA6AD
NOMESCO Finland
CT of neck arteries
1.7
9.6
161
945
J01MA02
ATC
ciprofloxacin; systemic
1.2
9.6
2214
19697
WX110, ,
SPAT
1.6
9.6
238
1543
103
Kela drug reimbursment
Diabetes, insulin-treated
1.2
9.5
1532
13175
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
2.0
9.5
105
541
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
1.5
9.5
282
1901
M01AE01
ATC
ibuprofen; systemic, rectal
1.2
9.4
4956
47352
H35.29
ICD-10 Finland
Other proliferative retinopathy
100.2
9.4
10
*
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.2
9.4
1345
11431
H3601, E106,
ICD-10 Finland
+∞
9.4
9
*
H35.1
ICD-10 Finland
Retinopathy of prematurity
+∞
9.4
9
*
UJF32
NOMESCO Finland
Coloscopy
1.2
9.4
1548
13343
S22
ICPC
Nail symptom/complaint
1.5
9.3
338
2370
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.4
9.3
432
3166
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
1.8
9.3
146
842
SFA30
NOMESCO Finland
Three-surface restoration
1.2
9.3
2091
18550
R74
ICPC
Upper respiratory infection acute
1.2
9.2
1094
9109
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
9.2
1011
8348
G04CA01
ATC
alfuzosin; oral
1.3
9.2
776
6208
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
2.6
9.2
49
186
L04
ICPC
Chest symptom/complaint
1.5
9.1
302
2082
K02.0
ICD-10 Finland
Caries limited to enamel
1.3
9.1
607
4704
R21
ICPC
Throat symptom/complaint
1.3
9.1
696
5496
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.4
9.1
333
2340
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.2
9.1
1340
11419
C08CA13
ATC
lercanidipine; oral
1.3
9.1
867
7043
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.4
9.1
464
3456
R53
ICD-10 Finland
Malaise and fatigue
1.2
9.0
1139
9548
L28
ICPC
Limited function/disability (L)
1.2
9.0
1050
8730
H29
ICPC
Ear symptom/complaint other
1.3
8.9
627
4894
S01BA07
ATC
fluorometholone; ophthalmic
2.2
8.9
69
311
NF1AA
NOMESCO Finland
Hip X-ray examination
1.3
8.9
526
4005
3643
FHL
Vitrectomy through pars Plana
24.0
8.9
12
5
R06AX27
ATC
desloratadine; oral
1.2
8.9
1098
9181
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.4
8.9
329
2317
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
1.7
8.9
140
808
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
2.9
8.9
41
144
A01
ICPC
Pain general/multiple sites
1.4
8.9
462
3450
L29
ICPC
Musculoskeletal sympt/complt other
1.4
8.8
433
3204
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
3.1
8.8
35
113
D07AC01
ATC
betamethasone; topical
1.2
8.8
1891
16689
WX001
NOMESCO Finland
Nonpharmacological sedation or pain relief
9.5
8.8
17
18
G04CA52
ATC
tamsulosin and dutasteride; systemic
1.3
8.7
690
5473
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.4
8.7
407
2987
L04AX03
ATC
methotrexate; systemic
1.4
8.7
452
3375
CHD00
NOMESCO Finland
Laser trabeculoplasty
2.1
8.7
77
367
ZXD05
NOMESCO Finland
Urgent procedure
1.2
8.7
1489
12870
T90
ICPC
Diabetes non-insulin dependent
1.2
8.6
1429
12304
R01AD12
ATC
fluticasone furoate; nasal
1.2
8.6
1227
10407
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
3.5
8.6
29
84
B05DB
ATC
Hypertonic solutions
3.1
8.6
34
109
H40
ICD-10 Finland
Glaucoma
2.2
8.6
67
303
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
3.7
8.6
26
70
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.5
8.6
293
2032
D01BA02
ATC
terbinafine; oral
1.2
8.6
1382
11869
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
8.6
1242
10556
H40.1
ICD-10 Finland
Primary open-angle glaucoma
3.6
8.5
27
75
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
10.0
8.5
16
16
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
1.9
8.5
107
577
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.5
8.5
246
1651
NGQ20
NOMESCO Finland
Amputation of lower leg
3.2
8.5
33
105
A10AB06
ATC
insulin glulisine; parenteral
2.6
8.5
47
182
G04BD12
ATC
mirabegron; oral
1.3
8.5
749
6024
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
1.7
8.5
158
956
G44.2
ICD-10 Finland
Tension-type headache
1.3
8.4
561
4346
SPAT1009
SPAT
Measurement of intraocular pressure
2.0
8.4
82
405
B35.1
ICD-10 Finland
Tinea unguium
1.4
8.4
310
2182
G04CB01
ATC
finasteride; oral
1.3
8.4
727
5832
H35
ICD-10 Finland
Other retinal disorders
12.8
8.4
14
11
L16
ICPC
Ankle symptom/complaint
1.3
8.4
521
3999
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.2
8.3
1182
10020
H3601, E107,
ICD-10 Finland
+∞
8.3
8
*
N03AX12
ATC
[U] gabapentin; oral
1.3
8.3
848
6936
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
1.7
8.3
151
907
VALMI, ,
NOMESCO Finland
1.2
8.3
1006
8389
SGA04
NOMESCO Finland
Opening and preparing the root canals, extremely complicated
1.4
8.3
364
2644
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.3
8.3
543
4198
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.4
8.3
383
2807
EB1SA, ,
SPAT
1.6
8.2
190
1212
J01DA06
ATC
[U] cefuroxime
1.3
8.2
656
5208
UKC02
NOMESCO Finland
Cystoscopy
1.2
8.2
995
8297
D11
ICPC
Diarrhoea
1.4
8.2
439
3293
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
8.2
1757
15479
ZYC01
NOMESCO Finland
Remote contact by phone
1.5
8.2
244
1648
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.3
8.2
493
3767
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.5
8.1
240
1617
R06AX22
ATC
ebastine; oral
1.3
8.1
692
5539
M01AE02
ATC
naproxen; oral, rectal
1.2
8.1
2790
25541
C09CA01
ATC
losartan; oral
1.2
8.1
1533
13354
CG2S4
NOMESCO Finland
Photography of cornea
3.2
8.1
31
98
SPAT1262
SPAT
Handing over of treatment supplies
1.2
8.1
995
8313
D01
ICPC
Abdominal pain/cramps general
1.3
8.0
499
3828
M02AA07
ATC
piroxicam; topical
1.2
8.0
1999
17831
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.4
8.0
422
3159
H26.3
ICD-10 Finland
Drug-induced cataract
2.9
8.0
36
125
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.3
8.0
541
4203
J01FA06
ATC
roxithromycin; oral
1.2
8.0
2017
18014
ZXC20
NOMESCO Finland
Use of chemical agents
1.8
8.0
120
685
B05DA
ATC
Isotonic solutions
2.9
7.9
35
120
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.5
7.9
275
1917
H02AB07
ATC
prednisone; oral
1.3
7.9
701
5643
M48.0
ICD-10 Finland
Spinal stenosis
1.3
7.9
751
6096
Z01.9
ICD-10 Finland
Special examination, unspecified
1.4
7.9
296
2093
ZXD35
NOMESCO Finland
Usual procedure
1.6
7.8
154
945
XCK20, ,
NOMESCO Finland
3.6
7.8
25
70
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
2.7
7.8
40
149
S01BA04
ATC
prednisolone; ophthalmic
1.9
7.8
99
536
F16
ICPC
Eyelid symptom/complaint
1.5
7.8
236
1599
TCG10
NOMESCO Finland
Removal of sutures from cornea
2.9
7.8
34
116
SPAT1325
SPAT
Vaccination
1.2
7.8
2032
18186
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
1.5
7.7
209
1385
H27.0
ICD-10 Finland
Aphakia
4.3
7.7
19
44
K59.09
ICD-10 Finland
Constipation, unspecified
1.4
7.6
371
2741
J01CA04
ATC
amoxicillin; systemic
1.2
7.6
4349
41308
WX199
NOMESCO Finland
Other local analgesia
1.6
7.6
182
1172
L04AB01
ATC
etanercept; parenteral
2.2
7.6
59
267
171
Kela drug reimbursment
Degludekinsuliini
11.8
7.6
13
11
Z71
ICD-10 Finland
Persons encountering health services for other counselling and medical advice, not elsewhere classified
1.7
7.5
120
696
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.2
7.5
1652
14563
R5140
NOMESCO Finland
Monitoring the use of the aid
1.3
7.5
538
4210
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
10.0
7.5
14
14
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.4
7.5
385
2870
TPH04
NOMESCO Finland
Cathetrisation of vein
1.2
7.5
1178
10083
L57.0
ICD-10 Finland
Actinic keratosis
1.3
7.4
685
5534
R35
ICD-10 Finland
Polyuria
1.4
7.4
381
2840
N06AX11
ATC
mirtazapine; oral
1.2
7.4
1673
14781
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
1.4
7.4
337
2464
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.3
7.4
632
5061
ACC51
NOMESCO Finland
Release of median nerve
1.4
7.4
335
2448
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.2
7.4
1169
10007
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
2.3
7.4
51
220
H30.1
ICD-10 Finland
Disseminated chorioretinal inflammation
+∞
7.3
7
*
3625F
ICD-9 Finland
Other retinal disorders, Degeneration of macula and posterior pole[FIBROSIS PRAERETINALIS]
+∞
7.3
7
*
F13
ICPC
Eye sensation abnormal
1.7
7.3
130
779
K30
ICD-10 Finland
Functional dyspepsia
1.3
7.3
512
3998
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.5
7.3
246
1706
WX203
NOMESCO Finland
Infraclavicular plexus blockade
1.8
7.2
107
609
CD2S4
NOMESCO Finland
Photography of eye
2.8
7.2
35
127
D02
ICPC
Abdominal pain epigastric
1.4
7.2
270
1909
R06AE07
ATC
cetirizine; oral
1.2
7.2
2045
18401
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
0.5
7.2
51
1086
Z01.8
ICD-10 Finland
Other specified special examinations
1.2
7.1
1149
9848
L13
ICPC
Hip symptom/complaint
1.2
7.1
1041
8840
S02.54
ICD-10 Finland
Fracture of both the crown and the root
1.6
7.1
161
1024
Z96.4
ICD-10 Finland
Presence of endocrine implants
20.0
7.1
10
5
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
1.3
7.1
547
4322
H43
ICD-10 Finland
Disorders of vitreous body
2.9
7.1
31
106
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
2.9
7.1
31
106
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
7.9
7.1
15
19
H84
ICPC
Presbyacusis
1.5
7.1
234
1616
CFW99
NOMESCO Finland
Other operation on conjunctiva
3.8
7.1
21
56
M14.6*A52.1
ICD-10 Finland
Charcot's or tabetic arthropathy
6.0
7.1
18
30
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.2
7.1
877
7327
R83
ICPC
Respiratory infection other
1.2
7.0
772
6364
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.4
7.0
347
2572
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.3
7.0
485
3778
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.3
7.0
678
5510
A12AA04
ATC
calcium carbonate; oral
2.0
7.0
71
357
-69
ICPC
Other reason for encounter NEC
1.5
7.0
189
1252
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
2.4
7.0
45
188
M79.1
ICD-10 Finland
Myalgia
1.3
7.0
605
4854
H47.1
ICD-10 Finland
Papilloedema, unspecified
3.3
7.0
25
76
H53.0
ICD-10 Finland
Amblyopia ex anopsia
2.8
6.9
34
124
130
Kela drug reimbursment
Malignant tumour
0.7
6.9
316
4260
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.2
6.9
947
7990
TQW40
NOMESCO Finland
Remowal of suture of skin
1.4
6.9
351
2614
L88
ICPC
Rheumatoid/seropositive arthritis
1.5
6.9
192
1280
A10BB01
ATC
glibenclamide; oral
1.6
6.9
167
1080
CJF10
NOMESCO Finland
Secondary implantation of artificial lens in posterior chamber
7.5
6.9
15
20
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
2.1
6.9
62
299
J01AA02
ATC
doxycycline; systemic
1.2
6.9
4366
41609
BEF00, ,
SPAT
2.9
6.8
30
103
CK2P4
NOMESCO Finland
Optic nerve head light layer imaging (OCT)
2.8
6.8
32
114
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
1.8
6.8
100
568
CHD99
NOMESCO Finland
Other filtering operation
3.8
6.8
20
53
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
0.7
6.8
338
4495
J05AB11
ATC
valaciclovir; oral
1.3
6.8
679
5540
H50.31
ICD-10 Finland
Intermittent exotropia
2.9
6.8
31
109
Z2446
NOMESCO Finland
Social worker
1.4
6.8
249
1756
M65.3
ICD-10 Finland
Trigger finger
1.5
6.7
206
1401
Z02.4
ICD-10 Finland
Examination for driving licence
1.2
6.7
1880
16870
A29
ICPC
General symptom/complaint other
1.3
6.7
664
5409
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
1.8
6.7
102
585
TQW99
NOMESCO Finland
Other minor procedure on skin
1.4
6.7
284
2054
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.6
6.7
125
2000
C09CA06
ATC
candesartan; oral
1.2
6.7
1191
10302
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.3
6.7
512
4046
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.3
6.6
596
4801
Z49.2
ICD-10 Finland
Other dialysis
2.6
6.6
35
133
S01FA01
ATC
atropine; ophthalmic
3.6
6.6
21
59
G45.3
ICD-10 Finland
Amaurosis fugax
1.7
6.6
106
619
XF402
NOMESCO Finland
ECG with work load test
1.3
6.6
617
4998
K08.80
ICD-10 Finland
Toothache NOS
1.4
6.5
302
2215
R52.9
ICD-10 Finland
Pain, unspecified
1.3
6.5
460
3592
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
2.6
6.5
35
134
M14.6
ICD-10 Finland
Neuropathic arthropathy
10.0
6.5
12
12
-60
ICPC
Result test/procedure
1.4
6.5
299
2191
K04.1
ICD-10 Finland
Necrosis of pulp
1.3
6.5
421
3250
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.4
6.5
301
2209
137
Kela drug reimbursment
Uraemia requiring dialysis
2.5
6.5
37
146
H02AB06
ATC
prednisolone; systemic
1.1
6.5
2587
23807
D07AC13
ATC
mometasone; topical
1.2
6.5
1416
12456
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
1.4
6.5
226
1578
OAB50, ,
SPAT
1.4
6.5
273
1973
A91
ICPC
Abnormal result investigation NOS
1.4
6.5
249
1771
M54
ICD-10 Finland
Dorsalgia
1.3
6.5
468
3670
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.4
6.4
258
1848
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.5
6.4
186
1252
Z94.7
ICD-10 Finland
Corneal transplant status
2.9
6.4
28
96
S16
ICPC
Bruise/contusion
1.5
6.4
160
1043
Z73.6
ICD-10 Finland
Limitation of activities due to disability
2.2
6.4
48
215
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
1.5
6.4
196
1335
L02
ICPC
Back symptom/complaint
1.3
6.4
390
2989
H02AB02
ATC
dexamethasone; systemic
0.8
6.4
403
5179
R20.2
ICD-10 Finland
Paraesthesia of skin
1.4
6.3
280
2039
P06
ICPC
Sleep disturbance
1.3
6.3
464
3644
F01
ICPC
Eye pain
1.7
6.3
111
664
D07AB02
ATC
hydrocortisone butyrate; topical
1.2
6.3
1418
12500
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
2.8
6.3
30
108
I48.1
ICD-10 Finland
Persistent atrial fibrillation
1.4
6.3
247
1763
H44.1
ICD-10 Finland
Other endophthalmitis
11.0
6.3
11
10
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
1.4
6.3
316
2351
J01MA06
ATC
norfloxacin; oral
1.3
6.3
623
5078
L20
ICPC
Joint symptom/complaint NOS
1.5
6.3
163
1073
H3601, E1100,
ICD-10 Finland
+∞
6.2
6
*
37600
ICD-8 Finland
Detachment of retina, Primaria
+∞
6.2
6
*
H3601, E118,
ICD-10 Finland
+∞
6.2
6
*
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
1.5
6.2
192
1309
F51.0
ICD-10 Finland
Nonorganic insomnia
1.3
6.2
542
4350
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.3
6.2
479
3786
H50.1
ICD-10 Finland
Divergent concomitant strabismus
2.6
6.2
33
126
M54.4
ICD-10 Finland
Lumbago with sciatica
1.2
6.2
780
6524
L84
ICD-10 Finland
Corns and callosities
1.5
6.2
165
1092
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.2
6.2
951
8110
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
1.6
6.2
125
776
J01FA09
ATC
clarithromycin; systemic
1.2
6.2
1404
12387
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
1.3
6.2
595
4835
L14
ICPC
Leg/thigh symptom/complaint
1.3
6.2
397
3065
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.3
6.1
521
4170
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.2
6.1
1377
12137
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.2
6.1
1677
15011
H52.2
ICD-10 Finland
Astigmatism
2.0
6.1
64
327
I79.2*E10.5
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
12.5
6.1
10
8
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
1.6
6.1
122
756
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.3
6.1
514
4112
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.4
6.1
241
1725
F27
ICPC
Fear of eye disease
2.1
6.0
51
240
CWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in eye and adjacent structures
8.6
6.0
12
14
A08
ICPC
Swelling
1.4
6.0
273
1997
Z02.7
ICD-10 Finland
Issue of medical certificate
1.4
6.0
309
2306
R02
ICPC
Shortness of breath/dyspnoea
1.2
6.0
686
5677
N05AD01
ATC
haloperidol; systemic
0.5
6.0
41
883
C02AC05
ATC
moxonidine; oral
1.4
6.0
242
1736

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6141
56667
7.35
95.51
27.9
24.9
133.39
133.64
g/l
0.66
6054
55704
6140
56655
7.28
95.39
27.7
24.8
6.69
6.80
e9/l
3.61
5935
54737
6139
56657
7.19
94.93
27.6
24.7
30.48
30.46
pg
0.59
6053
55688
6139
56658
7.19
94.91
27.7
24.7
91.90
91.73
fl
2.28
6053
55689
6139
56662
7.18
94.81
27.8
24.8
4.41
4.42
e12/l
0.91
5936
54739
6137
56649
7.03
94.31
27.8
24.8
240.94
243.13
e9/l
1.83
5960
54950
6135
56624
6.90
94.10
28.0
24.9
39.72
39.72
%
0.01
5740
52087
6067
55541
4.68
93.94
22.4
19.9
3.99
3.99
mmol/l
0.23
5937
54087
6060
55466
4.53
93.14
22.1
19.7
139.68
139.69
mmol/l
0.08
5933
54094
6054
55376
4.43
93.10
12.7
11.5
24.57
25.14
u/l
1.51
5792
53024
5867
52815
2.94
90.11
6.1
5.5
2.58
2.62
mmol/l
3.23
5255
47577
5622
49935
2.30
83.20
7.3
6.4
41.13
40.40
mmol/mol
6.42
5109
45298
5727
51427
2.43
79.81
5.3
4.9
4.49
4.53
mmol/l
1.66
5132
46556
5672
50976
2.27
74.56
5.2
4.8
1.49
1.46
mmol/l
3.03
5033
45771
5758
52092
2.41
74.20
18.2
16.6
25.20
26.42
mg/l
1.81
4653
42244
5445
48232
2.03
73.69
5.3
4.9
2.41
2.12
mu/l
0.33
4881
43151
5065
43883
1.83
72.54
22.4
19.9
15.08
15.49
%
5.12
4978
43094
4608
39067
1.69
68.79
4.7
4.3
—
—
—
0
0
5813
53239
2.39
65.24
17.5
16.0
—
—
—
0
0
5716
52054
2.20
63.99
5.6
5.2
6.13
6.05
mmol/l
4.24
5080
46461
5485
49258
1.96
63.14
4.6
4.3
1.26
1.28
mmol/l
1.99
4822
43742
4581
39407
1.62
57.84
4.2
4.0
15.01
15.06
pmol/l
0.60
4042
35084
4640
40227
1.60
54.73
4.8
4.3
14.10
14.02
mm/h
0.12
4205
36729
3173
25402
1.51
53.43
2.2
2.1
97.20
93.97
pmol/l
3.16
1555
13101
2980
23550
1.51
53.40
11.0
10.4
0.00
0.00
e9/l
0.15
2447
19176
4915
43441
1.63
51.04
8.1
7.9
79.27
80.00
u/l
0.49
4591
40785
2649
20731
1.48
47.96
3.1
2.8
150.21
161.05
ug/l
1.17
2376
18788
2370
18138
1.50
47.94
4.6
4.1
7.40
7.40
ph
0.11
430
3404
4395
38107
1.52
47.19
5.1
4.6
—
—
—
0
0
2627
20577
1.48
47.06
4.2
3.9
100.94
116.66
e6/l
0.27
1868
14923
2126
15980
1.50
46.62
3.6
3.3
—
—
—
0
0
4301
37311
1.49
44.39
5.3
4.9
1954.36
1352.09
e6/l
0.17
36
575
2192
16732
1.48
43.84
3.6
3.3
0.40
0.48
e6/l
1.00
1672
12869
3354
27776
1.45
43.67
6.6
6.0
1.21
1.21
mmol/l
1.78
3039
25102
1924
14324
1.50
43.50
4.3
4.1
86.11
86.24
%
0.08
1876
14000
3251
26867
1.44
42.15
6.4
5.7
0.61
0.62
e9/l
0.51
2771
22870
2327
18077
1.46
42.04
3.7
3.4
108.22
76.59
e6/l
0.25
1770
13998
3088
25291
1.44
41.98
6.7
6.3
—
—
—
0
0
3254
26961
1.43
41.20
6.4
5.7
0.04
0.04
e9/l
0.84
2777
22958
1866
13929
1.49
41.14
6.6
6.9
—
—
—
0
0
3332
27805
1.43
40.06
6.6
5.9
0.20
0.20
e9/l
0.61
2857
24011
3294
27450
1.42
39.79
6.5
5.8
1.81
1.90
e9/l
2.53
2862
23878
3591
30398
1.43
39.70
7.4
6.7
1.21
1.21
mmol/l
2.72
3019
25705
3707
31585
1.43
39.36
9.0
9.2
4.13
4.22
e9/l
1.43
3196
27378
2783
22536
1.42
39.29
2.4
2.2
80.82
79.73
nmol/l
1.19
2418
19722
1945
14759
1.46
38.97
1.7
1.6
1.30
1.32
mmol/l
0.75
1589
12143
2988
24532
1.42
38.88
6.7
6.0
0.69
0.67
%
1.96
2769
22714
3070
25400
1.41
37.82
6.6
5.9
57.80
58.05
%
0.52
2858
23599
3067
25390
1.41
37.55
7.0
6.3
9.05
8.87
%
2.46
2851
23560
3048
25257
1.41
36.82
6.7
6.0
2.96
2.85
%
1.62
2825
23399
3102
25793
1.40
36.66
6.9
6.1
26.79
26.63
%
0.32
2888
23982
1342
9624
1.50
35.08
3.2
3.2
2.00
2.24
e6/l
0.50
747
5357
1428
10450
1.48
33.54
3.1
3.0
1.32
1.45
e6/l
0.11
830
6151
1918
14872
1.42
32.91
1.6
1.6
20.75
20.30
nmol/l
0.63
1602
12558
1566
11916
1.42
29.19
4.1
4.0
518.97
472.40
ng/l
0.13
1355
10161
3046
25846
1.35
28.77
5.2
4.8
35.05
34.79
g/l
1.73
2813
23896
2301
18703
1.37
28.75
3.6
3.2
403.00
378.43
mg/l
0.09
1450
11797
2324
18937
1.36
28.51
3.5
3.1
6.95
7.24
mmol/l
2.94
1886
15595
3851
33886
1.36
28.51
5.2
4.8
6.93
6.78
mmol/l
4.10
3644
31874
2452
20159
1.36
28.35
3.4
3.5
2.36
2.36
mmol/l
0.01
2087
17348
1875
14828
1.38
27.52
2.4
2.3
2.93
3.04
mg/l
1.20
1568
12575
2684
22442
1.34
27.49
2.3
2.2
—
—
—
0
0
1629
12643
1.39
26.63
3.4
3.4
0.79
0.81
ug/l
0.24
1234
9333
2236
18278
1.35
26.25
2.2
2.2
186.55
215.36
u/l
0.88
2080
17039
3093
26548
1.33
25.88
5.6
5.3
0.00
0.00
estimate
0.34
593
4909
1505
11575
1.40
25.83
3.0
3.2
2.46
2.46
mmol/l
0.74
1339
10124
1175
8663
1.44
25.60
1.6
1.5
2.67
2.61
g/l
0.26
635
4828
2382
19725
1.34
25.39
4.2
3.7
11.25
8.26
mg/mmol
2.32
1454
12208
1301
9804
1.41
25.03
1.4
1.2
1.76
1.83
u/ml
0.05
309
2412
3116
26878
1.32
24.69
4.3
4.0
0.01
0.00
estimate
0.28
576
4817
4520
41134
1.36
24.67
25.5
22.4
331.19
331.50
g/l
1.59
4507
40823
3080
26538
1.32
24.53
4.3
4.0
0.00
0.00
estimate
2.37
640
5301
3349
29208
1.32
24.38
19.6
17.7
1.32
1.33
inr
0.47
962
8126
3516
30908
1.32
24.00
3.3
3.2
52.98
54.55
u/l
0.43
3162
27934
2333
19379
1.33
23.91
3.2
3.1
1716.57
1462.87
ng/l
1.22
2026
16913
1539
12027
1.37
23.61
3.1
3.0
532.65
544.52
mosm/kgh2o
1.42
1278
10277
1612
12738
1.36
22.93
2.8
2.7
4.41
5.01
e6/l
1.32
1428
11404
897
6412
1.47
22.77
1.4
1.3
521.89
492.59
titre
0.18
190
1442
3432
30199
1.30
22.60
5.9
6.4
12.27
11.94
umol/l
0.57
3247
28687
2614
22196
1.31
22.39
6.0
5.6
3.13
3.96
ug/l
1.23
2322
19691
1237
9427
1.39
21.91
2.0
2.0
30.11
30.04
s
0.15
1206
9151
1650
13197
1.34
21.40
4.0
3.9
—
—
—
0
0
1099
8266
1.40
20.93
3.0
2.5
22.31
21.90
%
0.42
945
6955
1225
9416
1.37
20.41
3.0
2.5
12.60
12.34
umol/l
0.60
1127
8724
1847
15096
1.32
20.40
3.0
2.9
4830.10
5351.44
umol/l
0.20
1551
12884
1145
8711
1.39
20.31
3.0
2.5
2.25
2.27
g/l
0.66
1045
8011
1102
8364
1.39
19.77
1.3
1.3
38.59
39.27
iu/ml
0.05
342
2552
2124
17849
1.29
18.65
5.0
4.8
22.24
22.12
%
0.13
1151
9769
2472
21181
1.28
18.57
3.8
3.7
5.81
5.82
ph
0.04
99
865
762
5530
1.43
17.56
2.4
2.7
66.02
66.08
g/l
0.07
674
4959
726
5223
1.44
17.54
2.5
2.4
35.25
40.36
u/l
0.88
620
4467
970
7351
1.38
17.36
2.4
2.4
1.75
1.77
%
0.21
840
6499
1025
7922
1.35
16.08
1.3
1.3
—
—
—
0
0
841
6320
1.38
15.74
2.8
2.7
8.84
9.45
umol/l
0.35
745
5516
1017
7902
1.34
15.34
1.3
1.2
14.94
15.01
u/ml
0.01
298
2749
641
4656
1.42
14.59
2.1
2.5
—
—
—
0
0
1379
11396
1.27
12.90
1.6
1.7
1.57
1.45
mg/l
0.28
1066
8907
369
2467
1.53
12.81
1.9
2.5
9.79
10.14
g/l
1.05
309
2153
319
2067
1.57
12.75
1.7
2.4
37.69
37.39
g/l
0.38
260
1770
410
2813
1.49
12.58
5.3
4.0
24.11
24.22
mmol/l
0.32
402
2753
629
4669
1.39
12.56
4.3
3.6
96.85
92.92
ng/l
0.40
531
3955
463
3276
1.45
12.13
2.4
2.4
30.34
26.03
au/ml
0.20
23
171
493
3529
1.43
12.13
2.3
2.1
11.79
11.69
nmol/l
0.08
427
3029
1924
16611
1.23
12.02
3.3
3.3
31.43
36.67
u/l
3.27
1787
15615
385
2654
1.48
11.55
1.9
2.5
7.53
7.47
g/l
0.26
327
2363
421
2957
1.45
11.47
1.3
1.3
56.48
61.03
au/ml
0.12
18
165
1026
8285
1.29
11.42
2.2
2.0
—
—
—
0
0
631
4760
1.36
11.38
1.6
1.5
—
—
—
0
0
383
2648
1.48
11.32
1.9
2.5
3.79
3.69
g/l
0.53
325
2359
554
4099
1.39
11.26
1.7
1.5
—
—
—
0
0
281
1822
1.57
11.23
1.3
1.2
2.85
1.01
u/ml
0.68
27
192
361
2474
1.49
11.16
1.9
2.5
3.04
2.96
g/l
0.76
302
2186
711
5480
1.34
11.12
6.7
6.4
1.32
1.35
mmol/l
0.39
697
5346
226
1395
1.64
11.08
1.8
1.7
—
—
—
0
0
696
5351
1.34
11.07
2.0
2.0
142.71
151.94
ug/g
0.24
546
4152
732
5678
1.33
10.95
2.8
2.5
68.05
68.42
e9/l
0.10
530
4334
805
6340
1.31
10.79
1.4
1.3
—
—
—
0
0
608
4606
1.35
10.65
2.3
2.3
375.75
376.33
nmol/l
0.02
551
4196
568
4265
1.37
10.53
1.7
1.4
—
—
—
0
0
816
6468
1.30
10.42
1.9
1.8
—
—
—
0
0
2546
22829
1.20
10.30
4.3
4.0
130.75
66.32
ng/l
0.42
1988
17501
1944
17029
1.21
10.08
4.7
4.4
—
—
—
0
0
485
3580
1.38
10.00
1.2
1.2
—
—
—
0
0
376
2660
1.44
9.88
1.4
1.3
—
—
—
0
0
938
7631
1.27
9.72
1.4
1.3
—
—
—
0
0
967
7900
1.27
9.67
6.8
5.4
1.06
1.03
mmol/l
3.16
881
7298
592
4554
1.33
9.35
4.5
4.3
—
—
—
0
0
197
1228
1.62
9.34
1.4
1.3
—
—
—
0
0
484
3616
1.37
9.27
6.5
6.8
25.11
24.87
mmol/l
0.76
484
3591
378
2712
1.42
9.21
2.8
2.9
—
—
—
0
0
224
1452
1.56
9.03
1.2
1.2
—
—
—
0
0
2886
26353
1.18
9.01
2.7
2.7
—
—
—
0
0
127
713
1.80
8.85
1.6
1.3
122.45
126.42
u/ml
0.13
22
146
2125
18946
1.18
8.75
3.6
3.3
—
—
—
0
0
420
3104
1.38
8.61
1.5
1.6
1.52
1.59
g/l
0.93
353
2660
799
6467
1.27
8.58
1.4
1.4
—
—
—
0
0
150
896
1.69
8.43
1.4
1.2
28.70
47.58
u/ml
1.06
21
91
502
3844
1.33
8.18
2.9
2.8
10.82
10.42
g/l
0.99
453
3502
659
5239
1.29
8.17
8.5
7.6
—
—
—
0
0
1425
12324
1.20
8.16
1.9
1.8
1248.02
1156.34
nmol/l
2.55
994
9175
139
821
1.71
8.16
1.5
1.3
—
—
—
0
0
453
3420
1.35
8.12
8.4
8.4
24.28
24.41
mmol/l
0.39
436
3319
67
311
2.17
8.09
1.1
1.1
—
—
—
0
0
195
1263
1.56
7.93
1.2
1.2
68.89
118.79
titre
—
9
91
165
1028
1.62
7.91
1.1
1.1
—
—
—
0
0
197
1282
1.55
7.85
1.3
1.2
460.00
942.56
titre
—
8
43
2047
18343
1.17
7.69
2.6
2.5
—
—
—
0
0
317
2282
1.41
7.62
2.7
3.5
44.09
48.66
mg/l
0.22
250
1868
317
2283
1.41
7.60
2.7
3.5
69.51
84.70
mg/l
0.21
246
1865
341
2501
1.38
7.36
1.4
1.5
23.04
18.00
u/ml
—
8
61
216
1464
1.49
7.16
2.5
2.2
135.56
102.60
ug/min
0.44
125
835
1154
9924
1.20
6.90
3.0
3.1
0.82
0.81
mmol/l
1.80
1057
9247
304
2221
1.39
6.74
2.7
3.5
4.35
3.31
ratio
0.20
21
166
378
2860
1.34
6.72
3.3
3.2
4.35
4.36
pmol/l
0.05
331
2486
395
3016
1.33
6.60
1.8
1.9
1.25
1.39
g/l
0.60
351
2687
1987
17972
1.16
6.32
2.6
2.6
67.49
65.29
u/l
0.11
1779
16467
180
1216
1.49
6.12
1.4
1.2
2.66
3.19
u/ml
0.15
20
130
625
5111
1.25
6.12
4.2
3.9
1.22
1.23
mmol/l
0.69
538
4486
181
1230
1.49
5.99
1.4
1.3
3.99
6.21
u/ml
0.60
30
197
191
1312
1.47
5.99
1.4
1.2
31.38
34.83
u/ml
0.08
19
63
62
318
1.96
5.85
1.1
1.1
—
—
—
0
0
1645
14743
1.16
5.84
4.9
4.4
0.00
0.00
estimate
0.52
571
4688
200
1395
1.45
5.81
3.2
2.9
1.85
1.69
mg/l
1.38
173
1241
257
1882
1.38
5.67
1.2
1.1
61.00
217.72
titre
—
5
39
201
1415
1.43
5.57
1.8
1.5
0.23
0.24
g/l
0.50
189
1326
251
1842
1.38
5.48
3.4
3.4
—
—
—
0
0
97
583
1.67
5.48
1.3
1.2
26.75
61.48
u/ml
—
10
45
62
327
1.91
5.42
2.2
2.3
—
—
—
0
0
1502
13442
1.15
5.38
1.3
1.3
—
—
—
0
0
673
5626
1.22
5.36
8.8
6.4
11.48
10.48
mmol/l
2.83
641
5332
236
1732
1.38
5.17
1.5
1.4
282.38
267.62
ug/g
0.66
140
1057
204
1461
1.41
5.17
1.8
1.5
1.17
1.17
g/l
0.10
192
1368
195
1389
1.42
5.10
2.1
1.8
12.60
11.94
mg/l
0.52
185
1263
255
1902
1.36
5.06
1.7
2.0
21.85
21.76
s
0.10
225
1708
422
3381
1.27
4.96
2.5
2.5
—
—
—
0
0
334
2601
1.30
4.92
1.4
1.3
—
—
—
0
0
25
94
2.67
4.90
1.0
1.0
—
—
—
0
0
866
7473
1.18
4.90
6.8
6.7
0.89
1.16
mmol/l
1.26
697
5951
869
7513
1.18
4.81
6.8
6.7
12.21
12.03
kpa
0.49
831
7157
869
7516
1.18
4.78
6.8
6.7
5.05
5.09
kpa
0.47
830
7172
177
1255
1.42
4.77
3.8
2.8
—
—
—
0
0
529
4372
1.23
4.72
1.6
1.5
—
—
—
0
0
103
655
1.58
4.70
2.0
1.8
196.96
189.00
pmol/l
0.19
95
602
1564
14151
1.14
4.70
2.6
2.5
—
—
—
0
0
342
2689
1.29
4.69
1.2
1.2
—
—
—
0
0
112
732
1.54
4.55
1.2
1.1
—
—
—
0
0
26
105
2.48
4.45
5.7
4.5
—
—
—
0
0
230
1726
1.35
4.43
2.8
3.7
—
—
—
0
0
135
940
1.45
4.08
1.2
1.2
—
—
—
0
0
666
5718
1.18
4.00
4.9
3.7
1.62
1.97
mmol/l
1.81
578
4877
779
6782
1.17
3.96
7.1
7.0
95.90
95.45
%
1.57
751
6514
320
2560
1.26
3.87
2.2
2.0
—
—
—
0
0
175
1288
1.37
3.87
1.0
1.1
—
—
—
0
0
57
330
1.73
3.80
2.3
2.2
149.71
204.56
ug/min
0.17
14
77
109
739
1.48
3.80
1.3
1.3
13.94
11.98
u/l
0.50
87
590
506
4261
1.20
3.78
1.6
1.4
—
—
—
0
0
91
599
1.53
3.66
1.2
1.2
3.76
4.65
u/ml
0.42
42
252
1587
14572
1.12
3.63
3.5
3.3
—
—
—
0
0
327
2645
1.25
3.62
1.1
1.2
99.16
133.61
iu/ml
1.24
91
909
1458
13326
1.12
3.61
4.1
3.7
—
—
—
0
0
57
337
1.70
3.56
2.2
2.0
497.54
492.67
min
0.14
41
250
29
137
2.12
3.54
1.1
1.1
1376.52
1596.91
miu/ml
0.55
29
137
39
206
1.90
3.52
27.4
26.9
104.26
107.53
ug/l
0.14
33
174
64
392
1.64
3.50
1.3
1.2
197.69
158.92
titre
0.15
13
65
660
5741
1.17
3.40
4.8
3.7
5.77
5.83
kpa
0.81
644
5576
24
107
2.25
3.37
1.0
1.1
—
—
—
0
0
637
5539
1.17
3.30
1.4
1.4
—
—
—
0
0
222
1735
1.29
3.30
1.6
1.6
—
—
—
0
0
63
392
1.61
3.26
1.3
1.2
74.00
101.00
titre
—
5
10
99
683
1.46
3.22
1.2
1.2
295.12
287.77
u/ml
0.09
66
419
680
5956
1.16
3.21
4.8
3.7
7.38
7.38
ph
—
5
47
208
1618
1.30
3.21
4.2
4.2
7.42
7.42
ph
0.24
193
1473
706
6204
1.16
3.19
7.6
7.4
118.15
120.52
g/l
2.53
689
6023
205
1595
1.29
3.16
2.9
2.7
—
—
—
0
0
99
686
1.45
3.15
1.0
1.1
69.08
608.77
iu/ml
0.77
14
129
544
4700
1.17
3.07
4.0
3.1
4.68
4.48
kpa
1.16
529
4551
421
3561
1.20
3.05
8.8
9.0
—
—
—
0
0
654
5741
1.16
3.01
2.6
2.4
6.50
7.02
ug/l
0.37
561
4982
41
233
1.76
2.99
1.1
1.1
4.96
12.07
iu/ml
—
7
57
37
204
1.82
2.98
1.2
1.3
—
—
—
0
0
180
1390
1.30
2.96
4.2
4.4
2.48
2.74
mmol/l
0.74
146
962
18
75
2.40
2.96
10.3
12.7
4.78
5.18
mmol/l
0.40
18
75
180
1391
1.30
2.95
4.2
4.4
5.08
4.99
kpa
1.06
180
1368
645
5670
1.15
2.91
2.3
2.1
0.20
0.20
g/l
0.16
589
5261
190
1482
1.29
2.91
3.3
3.1
0.85
0.81
nmol/l
0.34
145
1146
181
1404
1.30
2.89
4.2
4.4
8.55
8.43
kpa
0.34
181
1380
102
725
1.41
2.87
2.1
2.5
1.11
1.30
g/24h
0.40
54
335
268
2185
1.24
2.84
2.2
2.2
270.75
677.42
ug/l
2.41
258
2063
132
982
1.35
2.83
1.4
1.5
29.99
32.32
g/l
1.21
116
880
422
3602
1.18
2.78
1.3
1.2
—
—
—
0
0
90
1268
0.71
2.78
3.6
3.6
24.67
30.40
mg/l
1.00
54
800
49
300
1.64
2.76
1.8
1.5
5.39
7.03
u/l
1.21
39
244
508
4409
1.17
2.74
3.9
3.9
0.09
0.28
%
0.98
117
1327
193
1522
1.28
2.73
1.5
1.7
—
—
—
0
0
194
1537
1.27
2.66
1.9
2.3
3.72
3.63
g/l
0.34
181
1457
84
586
1.44
2.64
1.1
1.2
—
—
—
0
0
103
746
1.39
2.63
1.4
1.5
—
—
—
0
0
13
49
2.66
2.62
1.3
1.1
—
—
—
0
0
177
1390
1.28
2.61
3.8
3.8
—
—
—
0
0
23
113
2.04
2.61
1.0
1.0
—
—
—
0
0
315
2640
1.20
2.57
1.3
1.3
122.89
247.17
u/ml
5.86
283
2397
79
549
1.44
2.55
1.2
1.1
—
—
—
0
0
149
1150
1.30
2.52
1.6
1.7
5.41
4.67
iu/l
0.19
41
334
106
778
1.37
2.51
1.3
1.3
0.68
1.20
nmol/l
0.47
101
745
11
37
2.98
2.48
1.1
1.1
—
—
—
0
0
11
37
2.98
2.48
1.1
1.1
—
—
—
0
0
52
333
1.57
2.47
1.1
1.3
—
—
—
0
0
104
764
1.37
2.46
1.6
1.6
—
—
—
0
0
106
782
1.36
2.44
1.3
1.3
0.16
0.30
nmol/l
—
8
63
17
76
2.24
2.43
1.8
1.5
—
—
—
0
0
128
973
1.32
2.42
2.0
1.8
4.69
4.84
mmol/24h
0.17
112
826
513
4505
1.15
2.39
3.8
3.8
0.60
0.69
%
0.48
145
1594
182
1453
1.26
2.38
2.4
2.3
129.60
126.86
g/l
0.76
126
1041
37
220
1.69
2.37
1.3
1.4
30.43
24.08
umol/l
0.49
32
212
171
1356
1.27
2.36
2.9
2.6
16.22
15.91
%
0.49
91
731
86
618
1.40
2.34
1.3
1.4
44.46
36.43
iu/l
1.16
63
516
122
930
1.32
2.29
1.2
1.4
—
—
—
0
0
73
512
1.43
2.28
1.3
1.3
—
—
—
0
0
114
861
1.33
2.28
1.5
1.5
1112.95
2483.14
e6/l
3.09
78
628
58
389
1.50
2.27
2.7
2.5
—
—
—
0
0
530
4693
1.14
2.21
4.0
3.9
0.09
0.11
%
0.19
141
1599
57
384
1.49
2.19
1.3
1.3
—
—
—
0
0
91
669
1.37
2.18
3.2
3.2
—
—
—
0
0
245
2041
1.21
2.18
3.0
2.9
0.34
0.30
g/l
0.39
117
817
121
933
1.30
2.11
1.4
1.4
—
—
—
0
0
104
786
1.33
2.10
1.5
1.5
97785.56
58245.79
e6/l
0.42
59
473
92
685
1.35
2.05
1.3
1.3
—
—
nmol/l
—
0
0
574
5138
1.13
2.04
4.0
3.5
—
—
—
0
0
143
1133
1.27
2.04
1.4
1.3
59.67
63.12
mmol/l
0.47
120
906
90
671
1.35
2.00
1.6
1.5
—
—
—
0
0
72
518
1.39
1.99
1.3
1.3
11.66
13.79
u/l
0.74
67
471
50
336
1.49
1.98
1.2
1.1
—
—
—
0
0
1380
12936
1.09
1.97
1.8
1.7
43007108.40
34413852.38
pmol/l
0.17
1051
10493
1928
18320
1.08
1.94
4.6
4.3
—
—
—
0
0
29
172
1.69
1.92
2.2
1.5
—
—
—
0
0
43
282
1.53
1.91
1.0
1.1
—
—
—
0
0
95
720
1.32
1.91
1.2
1.3
—
—
—
0
0
61
431
1.42
1.88
1.3
1.3
241.67
307.50
titre
—
6
44
97
739
1.32
1.88
1.9
1.6
0.76
0.85
g/l
0.36
70
554
8
28
2.86
1.86
1.6
3.4
—
—
—
0
0
11
46
2.39
1.85
1.2
1.0
—
—
—
0
0
47
317
1.49
1.85
1.1
1.1
4.13
11.90
nmol/l
—
5
73
550
4947
1.12
1.83
3.9
3.9
1.05
0.93
%
0.35
159
1843
92
700
1.32
1.81
1.2
1.3
—
—
—
0
0
37
238
1.56
1.81
1.5
1.4
170.54
188.99
pmol/l
0.18
37
238
25
145
1.73
1.80
1.7
1.6
10.28
9.59
ug/l
0.29
25
145
63
452
1.40
1.80
1.2
1.2
1.41
1.56
nmol/l
0.47
52
409
7
23
3.05
1.80
7.3
13.6
53.71
162.17
e6/l
—
7
18
63
453
1.39
1.78
1.4
1.5
—
—
—
0
0
99
764
1.30
1.77
1.7
1.4
43.89
66.35
mu/l
1.06
89
679
652
5933
1.11
1.77
2.7
2.9
223.33
207.06
ng/l
0.40
600
5458
6
18
3.34
1.74
1.2
1.0
—
—
—
0
0
36
233
1.55
1.72
2.4
2.4
—
—
—
0
0
91
698
1.31
1.71
1.1
1.1
—
—
—
0
0
5
13
3.85
1.71
54.6
7.2
—
—
—
0
0
41
274
1.50
1.70
1.1
1.1
—
—
—
0
0
144
1762
0.81
1.70
13.6
10.8
—
—
—
0
0
25
148
1.69
1.70
1.4
1.3
123.09
132.24
nmol/l
0.11
18
107
119
947
1.26
1.69
1.7
1.5
—
—
—
0
0
106
836
1.27
1.63
6.5
6.2
11.44
12.20
mg/l
1.03
99
761
31
197
1.58
1.62
1.1
1.3
7.76
17.02
umol/l
0.85
25
125
22
128
1.72
1.60
2.3
1.8
0.66
1.10
ug/l
0.95
22
120
139
1686
0.82
1.53
4.9
4.5
—
—
—
0
0
23
138
1.67
1.51
1.7
1.4
23.41
27.87
g/l
0.50
15
113
6
21
2.86
1.50
1.5
1.4
—
—
—
0
0
11
51
2.16
1.50
1.0
1.2
—
—
—
0
0
11
51
2.16
1.50
1.0
1.2
—
—
—
0
0
11
51
2.16
1.50
1.0
1.2
—
—
—
0
0
39
267
1.46
1.48
1.5
1.8
—
—
—
0
0
19
109
1.75
1.46
2.4
1.5
—
—
—
0
0
85
664
1.28
1.44
1.8
1.8
803.17
310.75
mu/l
0.55
77
613
6
22
2.73
1.43
1.3
1.5
—
—
—
0
0
92
727
1.27
1.43
3.3
2.4
—
—
—
0
0
95
755
1.26
1.41
1.8
2.2
—
—
—
0
0
39
270
1.45
1.41
1.4
1.2
0.88
1.24
nmol/l
2.04
29
208
133
1098
1.22
1.40
1.5
1.5
—
—
—
0
0
10
46
2.18
1.39
1.2
1.2
83.89
161.05
mmol/l
—
10
37
35
238
1.47
1.39
1.1
4.1
52.12
64.80
mg/l
0.80
25
173
26
166
1.57
1.37
1.1
1.1
—
—
—
0
0
48
348
1.38
1.36
3.1
3.5
—
—
—
0
0
49
357
1.38
1.35
1.0
1.1
1.41
2.41
u/ml
0.72
29
157
148
1241
1.20
1.34
2.7
2.4
34.69
34.03
umol/l
0.09
124
1095
0
38
0.00
1.34
0.0
1.1
—
—
—
0
0
29
191
1.52
1.34
1.8
1.5
—
—
—
0
0
128
1059
1.21
1.34
1.3
1.4
15.61
32.12
e6/l
1.01
92
808
64
488
1.31
1.32
2.6
2.2
598.09
643.03
ml
0.51
45
323
172
1466
1.18
1.31
1.1
1.1
—
—
—
0
0
128
1062
1.21
1.31
1.4
1.4
1510.89
1098.29
e6/l
0.23
98
860
118
972
1.22
1.30
2.3
1.4
0.75
0.83
nmol/l
0.75
89
808
41
292
1.41
1.30
1.0
1.1
0.28
1.28
u/ml
1.51
28
148
92
738
1.25
1.29
1.1
1.0
—
—
—
0
0
175
1496
1.17
1.29
1.5
1.6
16186.27
14869.11
e6/l
0.11
127
1059
82
650
1.27
1.27
1.1
1.1
1.58
1.54
g/l
0.40
71
575
66
509
1.30
1.27
1.2
1.2
—
—
—
0
0
15
84
1.79
1.26
2.3
1.7
10.99
8.71
mg/l
—
10
69
27
178
1.52
1.25
1.0
1.0
—
—
—
0
0
132
1104
1.20
1.25
1.1
1.2
—
—
—
0
0
6
25
2.40
1.24
1.8
1.5
248.83
338.92
umol/24h
—
6
25
292
2602
1.13
1.22
5.3
4.8
—
—
—
0
0
18
108
1.67
1.22
1.2
1.3
—
—
—
0
0
76
601
1.27
1.22
1.2
1.2
—
—
—
0
0
7
141
0.50
1.20
1.3
1.4
—
—
—
0
0
56
426
1.32
1.20
1.1
1.1
0.68
1.68
u/ml
1.28
33
212
39
535
0.73
1.19
1.1
1.2
6.49
7.87
mmol/l
2.85
34
453
16
94
1.70
1.17
1.4
1.2
—
—
—
0
0
164
1409
1.17
1.16
3.2
2.9
7.93
7.90
kpa
0.06
158
1371
128
1078
1.19
1.15
1.8
1.8
—
—
—
0
0
13
223
0.58
1.15
2.3
3.5
51.73
55.05
%
0.25
13
216
32
224
1.43
1.14
1.2
1.5
3.60
2.54
%
0.29
24
192
61
474
1.29
1.14
1.7
1.4
6.94
7.08
g/l
0.11
44
335
61
474
1.29
1.14
1.7
1.4
0.40
0.44
g/l
0.20
43
335
61
474
1.29
1.14
1.7
1.4
2.95
2.92
g/l
0.05
43
338
88
715
1.23
1.13
1.2
1.3
287.65
331.73
pmol/l
0.38
74
604
36
258
1.40
1.13
1.2
1.4
63.28
66.33
%
0.18
25
212
121
1016
1.19
1.13
4.2
3.0
—
—
—
0
0
52
397
1.31
1.10
1.2
1.2
—
—
—
0
0
166
1435
1.16
1.10
1.5
1.5
—
—
—
0
0
67
530
1.27
1.09
1.7
1.9
4.33
4.37
mg/l
0.03
62
499
17
268
0.63
1.08
1.1
1.2
5.70
6.20
mmol/l
2.22
17
248
10
52
1.92
1.06
1.2
1.4
—
—
—
0
0
278
3089
0.90
1.05
4.7
3.3
25.01
25.21
mmol/l
0.55
273
3000
482
4453
1.09
1.04
4.4
4.7
—
—
—
0
0
117
989
1.19
1.03
2.6
2.2
—
—
—
0
0
81
662
1.23
1.02
1.3
1.6
—
—
—
0
0
9
48
1.88
1.00
1.2
2.3
—
—
—
0
0
134
1153
1.17
0.97
1.1
1.3
48.00
178.18
titre
—
5
33
57
451
1.27
0.96
2.0
1.9
10.68
10.74
%
0.04
57
451
31
224
1.39
0.96
2.6
2.5
—
—
—
0
0
125
1073
1.17
0.94
1.3
1.3
4.03
3.81
mmol/l
1.17
116
1004
35
260
1.35
0.92
1.1
1.0
—
—
—
0
0
39
295
1.32
0.92
3.5
3.9
—
—
—
0
0
41
313
1.31
0.91
5.8
6.2
—
—
—
0
0
73
599
1.22
0.91
1.4
1.3
277.26
276.38
mosm/kgh2o
0.11
53
448
14
86
1.63
0.90
1.3
1.3
23.67
22.83
%
—
9
67
6
29
2.07
0.89
1.5
1.4
—
—
—
0
0
12
194
0.62
0.88
1.6
1.8
—
—
—
0
0
57
706
0.81
0.88
3.3
4.1
—
—
—
0
0
49
386
1.27
0.87
2.2
2.2
8.13
6.91
mmol/l
1.36
35
265
77
640
1.21
0.86
1.2
1.4
—
—
—
0
0
8
44
1.82
0.85
1.3
1.1
—
—
—
0
0
94
1105
0.85
0.85
3.2
3.4
1.22
1.67
%
1.17
79
969
17
112
1.52
0.84
1.1
1.1
—
—
—
0
0
227
2510
0.90
0.83
4.1
4.3
41.65
82.42
u/ml
1.73
218
2405
420
3904
1.08
0.83
4.1
3.7
7.42
7.42
ph
0.12
65
509
43
336
1.28
0.83
9.7
11.7
—
—
—
0
0
44
346
1.27
0.81
1.0
1.1
0.23
1.17
u/ml
1.72
24
140
13
81
1.61
0.81
1.1
1.2
88.10
128.81
ug/l
—
8
51
254
2313
1.10
0.80
4.3
3.9
1.33
1.40
mmol/l
0.64
249
2268
36
277
1.30
0.78
1.1
1.1
47.04
41.76
mg/l
0.27
27
240
114
990
1.15
0.78
1.3
1.3
—
—
—
0
0
38
295
1.29
0.78
1.2
1.1
—
—
—
0
0
18
123
1.46
0.77
1.1
1.1
—
—
—
0
0
16
107
1.50
0.76
5.8
3.8
35.06
61.50
u/l
0.95
16
102
19
132
1.44
0.75
1.1
1.0
—
—
—
0
0
15
99
1.52
0.75
1.7
1.7
—
—
—
0
0
20
141
1.42
0.74
1.1
1.2
—
—
—
0
0
56
679
0.82
0.74
3.6
3.5
55.30
57.56
%
0.26
43
564
34
263
1.29
0.72
1.1
1.1
303.77
289.82
mg/l
0.14
26
235
58
479
1.21
0.72
1.8
1.4
—
—
—
0
0
423
3960
1.07
0.72
4.2
3.7
5.10
5.14
kpa
0.55
394
3740
6
109
0.55
0.72
3.2
2.7
25.67
1196.41
u/l
—
6
104
11
68
1.62
0.71
1.2
1.1
16.17
17.23
g/l
0.14
11
59
5
26
1.92
0.70
1.4
1.3
—
—
—
0
0
176
1586
1.11
0.70
1.1
1.2
—
—
—
0
0
137
1217
1.13
0.70
1.3
1.4
—
—
—
0
0
5
27
1.85
0.68
1.0
1.1
0.12
0.07
u/ml
—
5
27
135
1201
1.13
0.68
3.4
2.9
—
—
—
0
0
20
144
1.39
0.67
2.0
2.3
6.64
8.06
mmol/l
1.58
11
92
43
347
1.24
0.67
1.0
1.1
—
—
—
0
0
50
413
1.21
0.64
4.9
5.1
18.31
101.93
u/ml
2.92
18
123
49
591
0.83
0.64
1.3
1.5
24.82
29.18
%
0.33
27
366
261
2414
1.08
0.63
4.3
4.0
24.64
25.02
mmol/l
1.32
234
2201
65
553
1.18
0.62
3.6
3.0
81.90
38.92
mg/l
0.63
49
400
46
379
1.22
0.61
1.4
1.6
—
—
—
0
0
24
312
0.77
0.60
1.5
1.5
2.86
4.01
%
—
7
74
0
20
0.00
0.60
0.0
1.5
—
2.92
—
0
20
0
20
0.00
0.60
0.0
1.1
—
4.98
—
0
13
82
713
1.15
0.60
1.2
1.2
—
—
—
0
0
22
289
0.76
0.60
1.1
1.1
—
—
—
0
0
23
174
1.32
0.59
1.8
2.1
22.69
48.26
u/l
0.88
23
157
13
186
0.70
0.59
2.9
1.9
—
—
—
0
0
138
1244
1.11
0.58
1.4
1.3
540.95
548.29
mg/l
0.07
132
1174
0
23
0.00
0.58
0.0
1.2
—
17.04
—
0
16
43
355
1.21
0.57
1.8
1.6
—
—
—
0
0
301
2814
1.07
0.57
4.0
3.8
—
—
—
0
0
40
328
1.22
0.57
1.3
1.5
13.01
14.03
umol/l
0.40
35
304
5
88
0.57
0.56
1.0
1.0
—
—
—
0
0
543
5177
1.05
0.55
1.6
1.5
—
—
—
0
0
30
239
1.26
0.55
1.2
1.2
46.80
61.12
%
—
5
34
40
330
1.21
0.54
1.2
1.3
1.05
1.14
promille
0.13
33
248
46
385
1.20
0.54
1.5
1.2
—
—
—
0
0
56
654
0.85
0.54
1.2
1.2
—
—
—
0
0
42
349
1.20
0.53
1.0
1.1
—
—
—
0
0
374
3535
1.06
0.52
3.1
3.3
5.12
5.34
e9/l
0.07
265
2682
70
799
0.87
0.50
3.2
2.4
—
—
—
0
0
20
153
1.31
0.50
1.1
1.4
—
—
—
0
0
159
1463
1.09
0.48
1.3
1.3
—
—
—
0
0
70
794
0.88
0.47
1.4
1.5
53.48
62.03
%
0.95
46
490
14
102
1.37
0.47
1.7
1.6
130.33
112.46
ug/l
—
9
86
39
327
1.19
0.47
1.1
1.0
308.38
289.06
mg/l
0.91
34
286
15
111
1.35
0.46
1.3
1.2
—
525.00
—
0
8
12
165
0.73
0.46
1.5
1.2
—
—
—
0
0
34
282
1.21
0.46
2.9
2.5
36.25
36.87
%
0.06
20
168
750
7247
1.04
0.45
4.0
4.1
10.50
24.52
ug/l
2.64
613
6027
25
309
0.81
0.45
1.1
1.4
—
—
—
0
0
132
1210
1.09
0.44
1.4
1.5
—
—
—
0
0
52
598
0.87
0.44
1.4
1.4
11627.08
164911.66
e6/l
4.78
40
400
27
220
1.23
0.43
1.2
1.2
1.05
1.08
ratio
0.95
11
66
260
2450
1.06
0.43
3.4
3.4
109.31
1917.64
u/ml
2.67
212
2097
26
211
1.23
0.43
1.2
1.2
143.65
160.74
mmol/24h
0.49
26
211
30
248
1.21
0.42
1.0
1.1
1.40
2.55
u/ml
0.69
16
113
43
369
1.17
0.41
2.2
2.6
7.42
7.43
ph
0.29
21
141
21
167
1.26
0.41
1.1
1.1
—
14.14
—
0
22
13
96
1.35
0.41
1.2
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
0.10
—
0
6
0
15
0.00
0.41
0.0
1.1
—
0.25
—
0
10
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
21.89
—
0
10
1218
11897
1.03
0.40
4.9
4.5
1.02
1.02
kg/l
0.86
178
1840
0
19
0.00
0.39
0.0
1.1
—
0.22
—
0
9
30
251
1.20
0.39
1.6
1.5
0.19
0.17
nmol/l
0.12
18
171
93
847
1.10
0.38
1.5
2.2
30.87
25.96
mg/l
0.21
15
205
9
68
1.32
0.37
1.0
1.2
6.52
138604.80
nmol/l
—
9
57
49
430
1.14
0.37
1.2
1.1
34.03
34.93
mmol/l
0.08
39
359
26
311
0.84
0.36
1.1
1.4
—
—
—
0
0
17
213
0.80
0.36
1.2
1.2
45.86
39.59
g/l
—
7
105
67
601
1.12
0.36
1.2
1.2
120.87
198.76
miu/ml
0.88
16
189
9
71
1.27
0.36
1.1
1.3
—
—
—
0
0
28
235
1.19
0.36
1.7
1.4
193.03
23.28
u/l
0.40
11
77
26
310
0.84
0.36
1.1
1.4
—
—
—
0
0
9
124
0.73
0.35
2.8
2.9
—
—
—
0
0
398
3824
1.04
0.35
3.7
3.2
—
—
—
0
0
11
82
1.34
0.34
2.0
1.3
—
—
—
0
0
6
45
1.33
0.33
1.5
1.2
—
—
—
0
0
18
145
1.24
0.33
20.7
7.4
—
—
—
0
0
112
1037
1.08
0.33
1.3
1.3
35.90
37.12
u/l
0.03
99
908
6
46
1.30
0.33
1.2
1.1
—
—
—
0
0
174
1641
1.06
0.32
3.5
3.0
24.68
24.91
mmol/l
0.36
169
1603
28
327
0.86
0.31
1.5
2.0
—
—
—
0
0
67
609
1.10
0.30
1.1
1.2
—
—
—
0
0
20
240
0.83
0.30
1.1
1.3
—
—
—
0
0
15
120
1.25
0.30
23.3
7.1
—
—
—
0
0
37
420
0.88
0.29
1.0
1.0
—
—
—
0
0
26
302
0.86
0.28
1.1
1.4
—
—
—
0
0
8
62
1.29
0.28
2.0
2.3
0.38
0.50
u/field
—
8
62
149
1577
0.94
0.28
1.3
1.4
—
—
—
0
0
18
149
1.21
0.27
2.5
1.9
—
—
—
0
0
427
4137
1.03
0.27
7.0
6.9
24.49
24.68
mmol/l
0.55
407
3927
25
289
0.86
0.26
1.1
1.4
—
—
—
0
0
17
141
1.21
0.26
1.0
1.1
—
—
—
0
0
5
74
0.68
0.26
1.4
1.4
—
—
—
0
0
15
123
1.22
0.25
1.1
1.1
—
—
—
0
0
34
303
1.12
0.23
1.1
1.3
—
—
—
0
0
5
38
1.32
0.23
1.2
1.2
—
—
—
0
0
195
2032
0.96
0.22
5.3
6.1
1.26
1.32
mmol/l
0.34
170
1790
5
41
1.22
0.22
1.0
1.4
—
—
—
0
0
43
472
0.91
0.21
1.0
1.0
313.13
326.92
ng/l
0.16
31
313
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
184.60
—
0
12
194
1864
1.04
0.21
1.3
1.2
—
—
—
0
0
43
471
0.91
0.21
1.0
1.0
738.55
685.14
ng/l
0.42
31
303
18
154
1.17
0.21
1.4
1.4
—
—
—
0
0
109
1033
1.06
0.20
2.3
2.4
—
—
—
0
0
326
3172
1.03
0.19
3.9
3.7
—
—
—
0
0
30
270
1.11
0.18
2.5
3.0
218.27
209.02
u/l
0.17
30
265
15
128
1.17
0.18
1.3
1.2
35.71
86.39
mu/l
—
10
92
11
132
0.83
0.18
1.7
1.5
265.82
122.59
ng/l
0.64
11
132
10
121
0.83
0.18
1.3
1.4
—
—
—
0
0
70
659
1.06
0.17
1.4
1.3
—
—
—
0
0
46
496
0.93
0.17
1.3
1.2
326.51
334.34
nmol/l
0.09
37
388
13
110
1.18
0.17
1.9
1.3
—
—
—
0
0
15
129
1.16
0.17
1.3
1.8
1.90
2.06
ug/l
—
8
66
5
68
0.74
0.17
3.0
2.3
—
—
—
0
0
74
699
1.06
0.16
7.6
5.6
7.76
7.30
mmol/l
0.53
62
577
81
769
1.05
0.16
1.2
1.3
—
—
—
0
0
7
89
0.79
0.14
1.0
1.1
—
—
—
0
0
23
208
1.11
0.14
1.3
1.7
—
—
—
0
0
115
1107
1.04
0.14
1.1
1.1
15.12
9.69
u/ml
—
9
74
32
296
1.08
0.13
2.0
1.8
2.83
2.30
u/field
0.15
23
196
9
110
0.82
0.13
1.0
1.1
—
—
—
0
0
29
314
0.92
0.12
1.2
1.3
0.53
1.17
u/ml
0.69
14
172
12
104
1.15
0.12
1.0
1.0
—
0.75
—
0
30
15
168
0.89
0.11
1.1
1.4
—
—
—
0
0
49
464
1.06
0.11
1.1
1.1
3.23
3.64
u/ml
0.09
16
130
269
2742
0.98
0.11
4.7
5.1
1.56
1.59
%
0.18
251
2560
15
134
1.12
0.10
2.5
2.1
2.87
3.42
ug/l
—
6
44
21
192
1.09
0.10
1.0
1.0
0.03
0.23
u/ml
—
8
72
388
3824
1.02
0.10
4.4
3.2
126.45
127.75
g/l
0.55
378
3720
39
369
1.06
0.09
3.7
2.8
—
—
—
0
0
144
1476
0.98
0.09
5.7
6.8
11.37
11.14
mmol/l
0.36
131
1315
144
1476
0.98
0.09
5.7
6.8
104.57
105.16
mmol/l
0.81
131
1315
266
2706
0.98
0.09
4.8
5.1
0.91
0.88
%
0.43
247
2528
145
1415
1.03
0.09
3.4
3.2
44.84
896.55
u/ml
3.47
131
1293
32
340
0.94
0.09
1.8
2.3
—
—
—
0
0
17
155
1.10
0.09
1.8
2.3
—
—
—
0
0
14
126
1.11
0.09
1.5
1.5
—
—
—
0
0
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
6
57
1.05
0.08
4.8
11.1
—
—
—
0
0
5
61
0.82
0.08
1.0
1.6
39.80
43.08
umol/l
—
5
61
22
236
0.93
0.08
1.0
1.1
1.44
1.89
u/ml
—
9
94
166
1693
0.98
0.08
1.5
1.4
—
—
—
0
0
6
72
0.83
0.07
1.2
1.1
—
—
—
0
0
23
215
1.07
0.07
1.3
1.2
188.70
328.84
ug/l
0.24
11
116
18
167
1.08
0.06
1.2
1.1
—
—
—
0
0
18
167
1.08
0.06
1.2
1.1
—
—
—
0
0
18
167
1.08
0.06
1.2
1.1
—
—
—
0
0
9
103
0.87
0.06
7.7
7.1
—
—
—
0
0
329
3255
1.01
0.06
2.6
2.9
0.16
0.30
e6/l
3.17
321
3192
11
121
0.91
0.06
1.3
1.4
—
—
—
0
0
35
365
0.96
0.06
1.3
1.8
—
—
—
0
0
67
687
0.97
0.05
4.8
4.3
356.80
347.08
umol/l
0.20
55
589
21
222
0.95
0.05
1.8
2.2
545.07
6463.64
e6/l
0.83
14
155
46
473
0.97
0.04
2.5
2.0
2.35
2.04
u/field
0.10
17
169
18
190
0.95
0.04
1.1
1.1
—
—
—
0
0
96
975
0.98
0.03
3.0
2.7
—
—
—
0
0
17
161
1.06
0.03
2.2
2.0
25.59
32.27
%
1.64
17
146
78
768
1.02
0.03
1.7
1.6
—
—
—
0
0
649
6467
1.00
0.02
4.9
4.3
—
—
—
0
0
275
2765
0.99
0.02
1.9
2.0
5.07
2.13
ug/l
0.79
229
2428
32
328
0.98
0.01
2.5
1.6
77.03
89.15
umol/l
1.91
32
328
21
203
1.03
0.01
2.5
2.0
—
—
—
0
0
11
116
0.95
0.00
1.3
1.7
—
—
—
0
0
11
116
0.95
0.00
5.1
6.4
—
—
—
0
0
771
7717
1.00
0.00
5.4
4.9
33.46
33.08
%
0.42
502
5014
14
145
0.97
0.00
1.9
1.8
—
—
—
0
0
20
195
1.03
0.00
1.2
1.1
—
—
—
0
0
18
176
1.02
0.00
1.7
1.3
11.67
24.70
%
2.89
12
148
13
127
1.02
0.00
1.4
1.2
1.75
1.63
mmol/l
—
6
82
17
167
1.02
0.00
1.2
1.5
73.35
204.71
nmol/24h
1.10
17
167
40
396
1.01
0.00
1.1
1.2
—
—
—
0
0
20
201
1.00
0.00
1.7
2.1
3933.08
20652.96
e6/l
1.04
12
118
21
209
1.00
0.00
1.5
1.4
1.66
1.57
g/l
0.74
21
209
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
6
68
0.88
-0.00
1.2
1.3
—
—
—
0
0
18
180
1.00
-0.00
1.3
1.5
48.00
135.02
umol/l
2.55
13
97
22
220
1.00
-0.00
1.6
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
83
0.96
-0.00
1.1
1.2
40.41
45.53
mg/l
—
8
67
6
68
0.88
-0.00
1.5
1.1
—
—
—
0
0
5
56
0.89
-0.00
1.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint MACULAR_PUCKER and mortality.

Females

Parameter HR [95% CI] p-value
MACULAR_PUCKER 0.774 [0.65, 0.93] 0.005
Birth year 0.995 [0.99, 1.0] 0.204

During the follow-up period (1.1.1998 — 31.12.2019), 810 out of 10656 females with MACULAR_PUCKER died.

Males

Parameter HR [95% CI] p-value
MACULAR_PUCKER 0.757 [0.63, 0.92] 0.004
Birth year 0.986 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 1119 out of 9856 males with MACULAR_PUCKER died.

Mortality risk

Mortality risk for people of age

years, who have MACULAR_PUCKER.

N-year risk Females Males
1 0.09% 0.136%
5 0.482% 0.823%
10 1.155% 2.18%
15 2.192% 3.949%
20 3.793% 6.763%

Relationships between endpoints

Index endpoint: MACULAR_PUCKER – Macular pucker

GWS hits: 15

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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