No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2649 |
4. Check minimum number of eventsNone |
2649 |
5. Include endpointsNone |
2649 |
6. Filter based on genotype QC (FinnGen only) |
2552 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H52
- Name in latin
- Presbyopia
Similar endpoints
↥List of similar endpoints to
Presbyopia
based on the number of shared cases.
Similar with more cases:
- Disorders of refraction and accommodation
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12798 | 7185 | 5554 |
| Only index persons | 11977 | 6753 | 5224 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.18 | 0.21 | 0.16 |
| Only index persons | 0.23 | 0.25 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 53.91 | 54.12 | 53.65 |
| Only index persons | 53.71 | 53.84 | 53.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2552 | 1623 | 929 |
| Unadjusted period prevalence (%) | 0.52 | 0.58 | 0.43 |
| Median age at first event (years) | 55.48 | 54.78 | 56.70 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2649
- Matched controls
- 26490
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H52.4
ICD-10 Finland
Presbyopia
1189.3
307.7
2495
356
H52.0
ICD-10 Finland
Hypermetropia
33.0
307.7
292
99
H52.1
ICD-10 Finland
Myopia
15.7
288.5
257
180
H52.2
ICD-10 Finland
Astigmatism
26.7
272.1
189
76
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
162.2
154
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.1
147.8
817
3289
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.3
94.7
1317
7953
CGD20
NOMESCO Finland
Laser-assisted in situ keratomileusis
791.3
78.8
77
*
H50.52
ICD-10 Finland
Exophoria
21.2
66.5
50
24
CJE40
NOMESCO Finland
Phakoemulsification with implantation of skleralt fixed artificial lens in posterior chamber
324.7
63.7
64
*
XCK00
NOMESCO Finland
Perimetry
3.6
60.8
209
609
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
56.7
410
1808
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
14.3
49.4
45
32
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.8
40.7
824
5274
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
37.6
36
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.3
35.6
294
1361
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.2
29.0
261
1250
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
28.6
207
903
H53.2
ICD-10 Finland
Diplopia
3.5
26.1
89
257
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
22.9
22
*
ZXA10
NOMESCO Finland
Bilateral
1.7
21.7
425
2633
H26.4
ICD-10 Finland
After-cataract
2.2
21.3
183
858
R51.80
ICD-10 Finland
Headache
1.7
20.7
411
2555
N03AX12
ATC
[U] gabapentin; oral
1.7
20.3
450
2880
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.3
19.8
151
673
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
19.4
415
2629
H50.1
ICD-10 Finland
Divergent concomitant strabismus
100.8
18.6
20
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.9
17.8
232
1266
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
17.7
17
*
H25.0
ICD-10 Finland
Senile incipient cataract
2.2
17.3
144
666
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.9
17.3
215
1155
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.9
17.0
215
1163
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.4
16.9
60
179
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
16.2
883
6832
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
15.8
217
1206
H50.31
ICD-10 Finland
Intermittent exotropia
80.6
14.6
16
*
H52.5
ICD-10 Finland
Disorders of accommodation
150.8
14.5
15
*
H50.0
ICD-10 Finland
Convergent concomitant strabismus
150.8
14.5
15
*
H53.0
ICD-10 Finland
Amblyopia ex anopsia
6.2
14.2
24
39
AA1AD
NOMESCO Finland
CT of head and brain
1.5
14.0
569
4147
R42
ICD-10 Finland
Dizziness and giddiness
1.5
13.9
493
3492
J02AC01
ATC
fluconazole; systemic
1.4
13.8
1060
8640
N02AX02
ATC
tramadol; systemic, rectal
1.4
13.3
1066
8732
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
13.2
557
4085
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
12.9
255
1575
A02BC05
ATC
esomeprazole; systemic
1.4
12.8
1032
8448
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
12.8
551
4052
H02.3
ICD-10 Finland
Blepharochalasis
1.9
12.8
151
798
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
12.6
232
1406
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
12.1
180
1025
H54.7
ICD-10 Finland
Unspecified visual loss
5.7
11.9
22
39
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
11.8
383
2659
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
35.2
11.3
14
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
11.2
834
6707
M03BX02
ATC
tizanidine; oral
1.3
11.2
1702
15186
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
10.9
216
1335
R06AX27
ATC
desloratadine; oral
1.4
10.8
717
5661
E0000UV, ,
ATC
1.3
10.8
959
7913
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
110.5
10.4
11
*
G35
ICD-10 Finland
Multiple sclerosis
2.8
10.3
50
180
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
10.3
578
4434
N02BE01
ATC
paracetamol; systemic, rectal
1.4
9.9
2263
21256
G04BD12
ATC
mirabegron; oral
1.6
9.9
232
1496
37600
ICD-8 Finland
Detachment of retina, Primaria
20.1
9.8
14
7
G44.2
ICD-10 Finland
Tension-type headache
1.5
9.7
327
2284
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.8
9.6
141
800
A02BC03
ATC
lansoprazole; oral
1.3
9.6
677
5380
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.3
9.6
72
321
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
100.4
9.4
10
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
9.4
627
4937
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
9.4
9
*
H50.51
ICD-10 Finland
Esophoria
21.8
9.3
13
6
UJF32
NOMESCO Finland
Coloscopy
1.4
9.3
573
4455
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
9.3
219
1413
XA800
NOMESCO Finland
Neuropsychological investigation
1.9
9.2
113
607
H46
ICD-10 Finland
Optic neuritis
3.4
9.0
32
96
H53.4
ICD-10 Finland
Visual field defects
2.7
9.0
47
177
K30
ICD-10 Finland
Functional dyspepsia
1.5
8.9
263
1785
J01MA02
ATC
ciprofloxacin; systemic
1.3
8.9
858
7111
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
8.8
1118
9599
TAB00
NOMESCO Finland
Lumbar puncture
1.9
8.8
107
572
H50.2
ICD-10 Finland
Vertical strabismus
14.1
8.7
14
10
H43.3
ICD-10 Finland
Other vitreous opacities
2.9
8.6
40
141
L04AX01
ATC
azathioprine; systemic
2.0
8.6
97
506
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
3.0
8.6
36
120
N03AX16
ATC
[U] pregabalin
1.4
8.6
558
4371
R55
ICD-10 Finland
Syncope and collapse
1.6
8.4
194
1246
N06AX11
ATC
mirtazapine; oral
1.3
8.3
785
6480
A98
ICPC
Health maint/preventive medicine
1.9
8.1
2562
24884
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
8.1
421
3179
R01AD12
ATC
fluticasone furoate; nasal
1.3
8.1
785
6497
N06AX21
ATC
duloxetine; oral
1.5
8.1
298
2117
183
Kela drug reimbursment
Lamotrigin and topiramate
3.8
8.1
24
64
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
1.5
8.1
247
1691
M25.5
ICD-10 Finland
Pain in joint
1.3
8.0
822
6848
R01AD58
ATC
fluticasone, combinations; nasal
1.3
8.0
614
4920
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.8
7.8
108
603
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.7
7.8
155
959
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
7.8
657
5335
R30.1
ICD-10 Finland
Vesical tenesmus
2.5
7.7
45
180
N05CF02
ATC
zolpidem; oral
1.4
7.6
431
3297
H02AB06
ATC
prednisolone; systemic
1.3
7.5
1106
9613
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
3.0
7.5
31
103
R06.0
ICD-10 Finland
Dyspnoea
1.3
7.5
545
4333
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
80.3
7.4
8
*
J01DB01
ATC
cefalexin; oral
1.3
7.4
2071
19398
G81.9
ICD-10 Finland
Hemiplegia, unspecified
3.2
7.4
28
88
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
7.4
1085
9424
R01AD09
ATC
mometasone; nasal
1.3
7.3
1139
9955
ZXE00
NOMESCO Finland
One hour or less
1.3
7.3
864
7314
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
3.5
7.3
24
69
J05AB11
ATC
valaciclovir; oral
1.4
7.2
326
2401
N03AX14
ATC
levetiracetam; systemic
2.1
7.2
62
294
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.5
7.2
230
1590
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.1
275
1970
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
3.0
7.1
30
101
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
2.3
7.1
52
231
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
7.0
130
790
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.3
7.0
467
3660
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
7.0
237
1656
H93.1
ICD-10 Finland
Tinnitus
1.6
7.0
156
995
Z2221
NOMESCO Finland
Medical doctor
1.3
7.0
588
4765
103
Kela drug reimbursment
Diabetes, insulin-treated
0.7
7.0
321
4258
109
Kela drug reimbursment
Multiple sclerosis
2.7
6.9
35
130
R03AK07
ATC
formoterol and budesonide; inhalant
1.3
6.9
518
4128
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
6.7
213
1470
W49
ICD-10 Finland
Exposure to other and unspecified inanimate mechanical forces
2.6
6.7
38
150
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.3
6.7
46
199
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
6.7
571
4633
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.6
6.6
155
1000
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
6.6
1159
10223
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.0
6.6
66
331
M54.4
ICD-10 Finland
Lumbago with sciatica
1.3
6.6
427
3332
J01FA10
ATC
azithromycin; systemic
1.2
6.6
1429
12897
SPAT1312
SPAT
General health counselling
1.3
6.5
610
5004
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
1.9
6.5
76
403
D06BX01
ATC
metronidazole; topical
1.4
6.5
253
1815
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
6.5
1025
8935
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.4
6.5
265
1918
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.6
6.5
154
997
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.5
6.5
190
1289
G50.0
ICD-10 Finland
Trigeminal neuralgia
2.4
6.5
44
189
R35
ICD-10 Finland
Polyuria
1.7
6.5
122
746
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
6.5
967
8380
ZXA00
NOMESCO Finland
Right side
1.3
6.5
544
4402
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.4
6.4
286
2101
ND1AA
NOMESCO Finland
Wrist X-ray examination
1.6
6.4
139
880
H50.30
ICD-10 Finland
Intermittent esotropy
70.0
6.4
7
*
M54.5
ICD-10 Finland
Low back pain
1.2
6.4
847
7240
XKD00
NOMESCO Finland
Uroflowmetry
1.4
6.4
242
1728
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
1.6
6.4
127
788
A02BC02
ATC
pantoprazole; systemic
1.2
6.4
1668
15331
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.3
1258
11229
R03AC02
ATC
salbutamol; inhalant
1.2
6.3
1311
11753
R03DC03
ATC
montelukast; oral
1.3
6.3
390
3021
X58
ICD-10 Finland
Exposure to other specified factors
1.4
6.3
312
2334
R4120
NOMESCO Finland
Occupational therapy
1.6
6.3
144
925
H57.1
ICD-10 Finland
Ocular pain
1.8
6.3
83
459
R03BA08
ATC
ciclesonide; inhalant
1.5
6.3
199
1374
37000
ICD-8 Finland
Refractive errors, Astigmatismus
+∞
6.3
6
*
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
26.7
6.2
8
*
R06AE07
ATC
cetirizine; oral
1.2
6.2
1033
9044
215
Kela drug reimbursment
Diabetes, non-insulin-treated
0.7
6.2
313
4100
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
6.2
596
4906
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.1
565
4624
ZXD10
NOMESCO Finland
Scheduled procedure
1.2
6.1
854
7340
L57.0
ICD-10 Finland
Actinic keratosis
1.5
6.1
159
1054
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
2.9
6.0
27
94
N86
ICPC
Multiple sclerosis
3.5
6.0
20
58
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1112
9064
1.39
14.79
2.5
2.2
78.90
76.67
nmol/l
1.81
1031
8330
1250
10401
1.38
14.61
3.8
3.4
0.00
0.00
estimate
0.21
235
1949
1869
16638
1.42
14.47
4.5
4.0
10.38
11.17
mm/h
1.84
1752
15620
1259
10522
1.37
14.16
3.8
3.4
0.00
0.01
estimate
1.47
224
1796
1245
10415
1.37
13.78
5.1
4.5
0.00
0.00
estimate
0.80
226
1859
1340
11374
1.36
13.35
6.6
6.0
1.93
1.95
e9/l
0.16
1210
10168
811
6353
1.40
13.31
2.1
2.1
171.71
209.42
u/l
0.63
761
6009
2237
20735
1.51
12.83
5.2
4.6
1.79
2.04
mu/l
1.55
2098
19319
1348
11498
1.35
12.78
6.8
6.2
0.18
0.19
e9/l
2.05
1210
10191
1934
17482
1.39
12.47
4.4
4.0
14.51
14.60
pmol/l
0.98
1793
16217
1468
12789
1.33
11.55
9.8
9.4
3.81
3.98
e9/l
2.59
1309
11272
690
5424
1.37
10.65
4.1
3.8
0.00
0.01
estimate
1.60
217
1806
424
3071
1.45
10.49
1.9
2.1
29.61
29.70
s
0.07
414
2984
1520
13432
1.31
10.19
4.6
3.9
4816.61
1592.24
e6/l
0.66
28
170
508
3837
1.40
9.91
1.6
1.5
—
—
—
0
0
1088
9312
1.29
8.82
3.0
2.7
109.70
125.24
ug/l
1.83
1032
8779
963
8154
1.28
8.37
4.0
3.4
—
—
—
0
0
1201
10530
1.26
7.59
6.6
6.0
56.08
56.55
%
0.76
1145
9937
1172
10255
1.26
7.51
6.6
6.6
1.22
1.21
mmol/l
0.41
999
8819
630
5113
1.30
7.43
1.8
1.7
0.96
1.03
mg/l
0.14
484
3900
1069
9264
1.26
7.42
5.9
5.9
1.22
1.21
mmol/l
0.65
989
8543
346
2572
1.40
7.29
5.7
6.2
—
—
—
0
0
1174
10303
1.25
7.24
6.9
6.2
2.89
2.88
%
0.04
1114
9691
680
5595
1.29
7.19
4.0
3.8
94.84
94.04
%
0.40
658
5453
947
8138
1.25
6.95
1.9
1.9
98.29
97.33
pmol/l
0.26
488
4266
517
4120
1.32
6.91
2.4
2.4
5.01
5.86
e6/l
0.95
466
3707
1207
10668
1.24
6.85
7.0
6.2
29.38
28.72
%
1.46
1152
10078
225
1568
1.48
6.74
1.3
1.3
131.81
206.53
u/ml
1.59
210
1462
549
4429
1.30
6.69
4.1
3.7
1.02
1.02
kg/l
0.53
70
600
922
7925
1.25
6.69
3.2
3.2
99.28
45.04
ng/l
0.37
544
4892
1841
17068
1.26
6.67
8.1
7.6
74.97
77.07
u/l
0.93
1747
16224
88
487
1.83
6.61
1.2
1.3
16.66
22.68
e6/l
0.20
64
363
670
5555
1.28
6.58
2.9
2.9
0.40
0.41
e6/l
0.03
515
4140
88
488
1.83
6.57
1.3
1.4
1655.21
1818.05
e6/l
0.04
66
386
805
6869
1.25
6.12
2.6
2.6
57.34
71.40
u/l
0.64
734
6406
140
900
1.59
6.10
1.4
1.4
—
—
—
0
0
2071
19542
1.27
6.06
17.0
15.1
14.46
14.82
%
2.34
2036
19211
355
2728
1.35
6.06
2.4
2.3
102.86
126.80
ug/g
0.90
284
2217
718
6058
1.25
6.01
3.0
3.0
143.54
98.83
e6/l
0.26
562
4583
40
172
2.35
5.91
1.1
1.1
243.47
277.05
mg/l
0.74
32
154
225
1610
1.43
5.88
2.6
2.4
13.48
13.08
nmol/l
0.35
198
1467
2504
24341
1.52
5.74
11.5
10.1
26.47
27.35
u/l
1.97
2435
23695
2577
25232
1.78
5.64
21.2
18.8
41.00
41.03
%
0.03
2450
23918
2339
22484
1.34
5.58
14.2
12.8
21.12
21.86
mg/l
0.47
1863
17609
146
969
1.54
5.56
1.3
1.2
0.68
1.20
u/ml
0.42
13
84
488
3964
1.28
5.56
1.5
1.4
—
—
—
0
0
431
3447
1.30
5.54
2.6
2.5
0.97
0.99
e6/l
0.04
258
1896
40
178
2.27
5.49
1.1
1.2
34.09
39.67
mg/l
0.58
29
154
2580
25282
1.79
5.45
21.2
18.8
137.37
136.89
g/l
1.05
2560
25003
145
966
1.53
5.43
1.8
1.7
4.69
4.31
mg/l
0.08
107
728
2579
25277
1.77
5.34
21.1
18.7
4.53
4.54
e12/l
0.20
2544
24691
2419
23403
1.39
5.29
5.0
4.7
2.90
2.90
mmol/l
0.06
2270
22024
31
126
2.48
5.20
2.1
2.5
637.42
1091.26
u/ml
1.09
31
126
93
563
1.68
5.20
1.3
1.2
499.01
530.66
mg/l
0.36
86
534
2577
25262
1.74
5.19
21.1
18.7
254.87
257.08
e9/l
0.97
2549
24738
1047
9308
1.21
5.12
12.4
12.1
1.20
1.20
inr
0.02
343
2733
1253
11332
1.20
5.09
6.2
6.5
11.24
11.02
umol/l
0.16
1197
10827
269
2037
1.36
5.05
3.3
3.1
—
—
—
0
0
814
7069
1.22
5.05
3.3
3.5
2.35
2.36
mmol/l
0.33
721
6361
2577
25272
1.73
5.04
21.1
18.7
6.40
6.56
e9/l
3.11
2546
24680
2389
23094
1.35
5.01
4.6
4.3
4.86
4.84
mmol/l
0.47
2243
21849
112
718
1.58
5.00
1.8
1.7
—
—
—
0
0
1635
15184
1.20
4.87
3.0
2.9
—
—
—
0
0
1011
9011
1.20
4.70
5.1
4.8
36.41
36.13
g/l
0.97
931
8451
519
4338
1.24
4.59
1.5
1.5
20.71
20.93
nmol/l
0.14
455
3784
81
495
1.66
4.42
1.2
1.2
3.66
3.73
mmol/l
0.33
73
465
139
964
1.47
4.35
1.6
1.5
—
—
—
0
0
1343
12327
1.18
4.34
4.6
4.6
6.44
6.66
mmol/l
4.44
1272
11644
563
4775
1.23
4.32
2.3
2.1
2.74
2.94
mg/l
1.30
477
4120
2307
22275
1.28
4.25
4.1
3.9
1.28
1.34
mmol/l
3.93
2153
20859
2372
22989
1.30
4.20
4.6
4.3
1.52
1.48
mmol/l
4.61
2226
21661
195
1455
1.37
4.06
3.5
3.2
4.42
4.50
pmol/l
0.54
166
1293
440
3659
1.24
4.05
2.7
3.0
2.44
2.45
mmol/l
0.20
392
3211
105
701
1.52
3.98
1.8
1.5
113.80
0.44
iu/ml
0.48
29
130
514
4360
1.22
3.92
1.5
1.4
2.23
2.40
g/l
1.60
309
2790
2397
23297
1.30
3.89
15.2
14.0
3.95
3.96
mmol/l
0.97
2347
22766
105
706
1.51
3.86
1.3
1.3
—
—
—
0
0
2296
22210
1.25
3.79
4.5
4.3
5.72
5.89
mmol/l
11.56
2128
20678
28
127
2.22
3.76
1.0
1.1
0.98
2.65
nmol/l
—
8
25
2385
23200
1.28
3.58
15.1
13.9
139.81
139.79
mmol/l
0.18
2345
22704
97
653
1.50
3.57
1.2
1.1
—
—
—
0
0
100
681
1.49
3.49
1.8
1.9
37.04
38.83
nmol/l
0.49
95
655
2186
21077
1.21
3.48
5.3
5.2
38.54
39.37
mmol/mol
5.20
2056
19852
700
6184
1.18
3.39
4.4
4.2
2.10
2.13
ug/l
0.03
640
5639
92
621
1.50
3.36
1.4
1.4
297.80
286.78
ug/g
0.20
53
348
222
1740
1.30
3.34
2.6
2.7
10.30
10.51
g/l
0.34
201
1601
48
276
1.75
3.34
1.1
1.1
—
—
—
0
0
192
1476
1.32
3.33
3.2
3.6
86.01
81.87
ng/l
0.17
166
1312
68
430
1.60
3.32
3.7
3.6
57.71
57.06
%
0.17
68
430
684
6041
1.18
3.31
2.4
2.4
6062.90
3613.11
umol/l
0.73
606
5415
599
5234
1.19
3.29
2.6
2.8
554.23
942.97
ng/l
7.19
485
4380
2245
21731
1.22
3.27
12.8
11.5
83.64
83.77
ml/min/173m2
0.13
1905
18200
72
465
1.56
3.23
1.3
1.4
42.03
33.45
u/l
0.69
49
364
53
317
1.69
3.22
1.5
1.5
—
—
—
0
0
387
3260
1.22
3.15
1.9
1.7
1214.29
1177.24
nmol/l
0.31
281
2525
32
166
1.94
3.09
1.2
1.1
—
—
—
0
0
26
125
2.09
3.08
1.0
1.1
0.97
1.10
u/l
1.57
12
66
565
4949
1.18
3.00
1.3
1.3
1.78
1.70
u/ml
0.05
160
1420
374
3166
1.21
2.90
2.8
2.7
2.82
2.61
e6/l
0.15
203
1628
1698
16133
1.15
2.86
3.4
3.1
42.21
48.11
u/l
2.55
1597
15254
1071
9871
1.14
2.84
2.4
2.5
—
—
—
0
0
191
1503
1.29
2.83
1.7
1.7
—
—
—
0
0
230
1854
1.26
2.81
2.2
2.5
67.91
70.28
ml/min/173m2
0.47
96
691
564
4965
1.17
2.81
4.0
3.7
21.67
21.17
%
0.33
233
2168
90
630
1.44
2.80
2.5
2.1
9.95
11.73
mg/l
1.33
82
587
256
2091
1.25
2.79
2.4
2.2
350.61
367.06
nmol/l
0.77
241
1939
502
4385
1.18
2.74
1.3
1.3
27.07
29.00
iu/ml
0.16
149
1457
483
4213
1.18
2.69
1.3
1.3
9.65
9.81
u/ml
0.02
208
1763
29
155
1.88
2.61
1.0
1.1
8.18
9.53
iu/ml
—
9
43
56
364
1.55
2.51
1.4
1.3
—
—
—
0
0
56
364
1.55
2.51
1.4
1.3
—
—
—
0
0
16
69
2.33
2.48
1.0
1.3
97.88
94.00
%
—
8
33
315
2666
1.21
2.46
5.7
5.8
1.02
1.03
mmol/l
0.44
294
2498
46
287
1.61
2.46
1.3
1.2
—
—
—
0
0
55
359
1.54
2.43
1.2
1.4
0.34
0.26
nmol/l
0.56
36
252
16
70
2.29
2.41
1.0
1.1
98.25
91.45
%
—
8
33
15
64
2.35
2.38
5.8
4.0
—
—
—
0
0
50
321
1.57
2.38
1.5
1.4
0.61
0.62
nmol/l
0.09
50
308
309
2625
1.20
2.33
1.9
1.8
—
—
—
0
0
204
1661
1.25
2.33
1.8
2.2
9.16
8.07
ug/l
0.20
184
1498
195
1581
1.25
2.31
1.2
1.2
119.70
166.28
iu/ml
1.45
72
628
29
162
1.80
2.31
3.0
2.6
549.35
582.94
e6/l
0.13
20
139
128
985
1.31
2.29
2.6
2.0
39.88
39.96
u/l
0.01
119
893
7
18
3.90
2.25
1.1
1.0
—
—
—
0
0
9
29
3.11
2.22
1.2
1.0
—
—
—
0
0
26
143
1.83
2.19
1.0
1.0
862.21
769.31
ng/l
0.38
19
98
208
1711
1.23
2.18
1.7
1.7
—
—
—
0
0
37
226
1.65
2.18
1.1
1.1
—
—
—
0
0
208
1713
1.23
2.16
2.6
2.4
29.33
23.36
au/ml
0.25
11
156
26
146
1.79
2.06
1.0
1.0
39.16
43.25
ng/l
0.16
19
96
205
1699
1.22
2.02
7.8
7.8
1.36
1.34
mmol/l
0.15
198
1661
183
1501
1.24
1.99
1.3
1.3
32.70
35.55
iu/l
0.52
160
1305
86
639
1.36
1.98
1.6
1.7
—
—
—
0
0
85
632
1.36
1.96
2.4
2.9
—
—
—
0
0
392
3451
1.16
1.95
3.6
3.6
0.83
0.82
mmol/l
2.08
363
3275
104
801
1.31
1.90
1.7
1.8
—
—
—
0
0
25
143
1.76
1.89
1.0
1.0
351.61
296.72
ng/l
0.26
18
98
483
4332
1.14
1.85
1.7
1.6
49633699.33
37334841.27
pmol/l
0.11
409
3699
189
1569
1.22
1.85
1.4
1.3
33.58
49.36
au/ml
—
9
91
417
3703
1.15
1.85
2.8
2.8
0.65
0.72
ug/l
1.09
236
2236
831
7702
1.12
1.85
3.8
3.3
31.40
34.36
u/l
0.64
794
7345
223
2624
0.84
1.81
4.6
4.2
32.27
31.72
%
0.33
153
1886
8
29
2.76
1.79
3.0
2.2
—
—
—
0
0
53
372
1.43
1.73
1.2
1.1
—
—
—
0
0
35
227
1.55
1.68
1.1
1.0
—
—
—
0
0
196
1652
1.20
1.67
3.7
4.0
1.23
1.23
mmol/l
0.22
169
1450
8
31
2.59
1.66
3.0
1.8
—
—
—
0
0
26
157
1.66
1.65
1.5
1.7
—
—
—
0
0
240
2066
1.18
1.62
2.5
2.5
33.55
40.83
u/l
1.18
212
1800
45
311
1.45
1.61
1.9
2.0
1.56
1.71
mmol/l
0.73
45
305
83
636
1.31
1.61
2.3
2.5
3.34
3.59
g/l
1.02
78
601
31
198
1.57
1.59
1.2
1.4
228.98
209.53
pmol/l
0.10
31
198
6
20
3.00
1.58
1.3
1.8
59.00
39.50
umol/l
—
6
20
105
833
1.27
1.58
2.5
2.7
0.68
0.66
%
0.27
105
824
56
409
1.38
1.50
2.9
2.7
17.51
16.46
%
1.15
35
219
164
1375
1.21
1.50
1.9
1.8
1.43
1.35
g/l
0.11
149
1271
89
697
1.29
1.49
1.7
1.7
0.23
0.24
g/l
0.25
84
655
73
559
1.31
1.45
1.4
1.3
14.82
12.09
u/l
0.42
54
445
83
647
1.29
1.45
1.4
2.3
10.28
10.08
g/l
0.14
76
595
669
6203
1.11
1.45
1.7
1.7
1.34
1.43
mmol/l
2.42
554
5274
174
1473
1.19
1.44
2.7
2.7
166.76
146.69
ng/l
0.24
153
1327
97
772
1.27
1.44
1.9
1.8
—
—
—
0
0
25
156
1.61
1.43
3.3
2.7
0.24
0.21
e9/l
0.17
18
138
184
1567
1.19
1.43
2.1
2.7
66.62
66.79
g/l
0.11
169
1453
292
2581
1.15
1.42
2.8
2.8
7.80
7.43
umol/l
0.10
258
2275
242
2113
1.16
1.39
4.3
4.5
233.23
244.30
u/l
0.69
232
2003
7
29
2.42
1.39
1.0
1.0
—
—
—
0
0
5
17
2.94
1.36
21.0
12.1
6.22
5.38
mmol/l
—
5
17
54
400
1.36
1.35
2.9
2.7
8.29
8.13
kpa
0.26
54
395
18
105
1.72
1.33
1.2
1.3
150.50
171.28
mmol/24h
0.47
18
105
24
152
1.58
1.31
1.1
1.2
1.04
1.04
ratio
—
9
55
105
856
1.24
1.30
2.6
2.8
1.38
1.34
%
0.11
105
847
77
606
1.28
1.28
2.1
1.7
—
—
—
0
0
8
36
2.23
1.24
1.6
2.4
—
—
—
0
0
79
627
1.27
1.24
1.2
1.2
—
—
—
0
0
37
262
1.42
1.23
3.1
3.3
3.01
27.02
nmol/l
0.60
37
255
18
109
1.66
1.18
1.6
1.8
—
—
—
0
0
427
3912
1.11
1.18
3.5
3.4
406.87
487.79
ng/l
0.22
293
2771
138
1170
1.19
1.17
7.5
8.1
24.87
24.80
mmol/l
0.10
138
1162
70
552
1.28
1.17
1.5
2.2
38.27
38.15
g/l
0.05
63
501
0
35
0.00
1.15
0.0
1.0
—
—
—
0
0
99
816
1.22
1.13
1.7
1.7
—
—
—
0
0
69
546
1.27
1.13
1.5
2.2
0.05
0.02
g/l
0.27
62
512
69
546
1.27
1.13
1.4
1.2
57.18
44.01
u/ml
0.36
12
55
83
672
1.24
1.12
1.5
2.3
2.87
2.92
g/l
0.14
76
621
16
258
0.62
1.12
2.8
3.0
1.04
0.83
nmol/l
—
9
199
78
628
1.25
1.11
1.2
1.2
—
—
—
0
0
77
621
1.25
1.09
1.2
1.1
9.18
5.01
u/ml
0.35
13
85
18
112
1.61
1.08
1.5
1.6
3.02
6.25
nmol/l
0.69
12
89
19
120
1.59
1.08
6.8
8.2
28.20
54.20
u/ml
—
5
41
26
177
1.47
1.07
1.3
1.1
—
—
—
0
0
36
489
0.73
1.07
2.2
2.3
223.74
136.67
ug/min
0.43
23
297
57
444
1.29
1.07
1.2
1.5
—
18.56
—
0
10
55
427
1.29
1.06
3.6
4.5
5.10
5.04
kpa
0.29
55
420
26
178
1.47
1.05
1.3
1.1
—
—
—
0
0
25
170
1.48
1.04
1.8
2.0
—
—
—
0
0
37
272
1.37
1.03
1.7
1.6
46.22
57.64
%
0.89
23
165
11
60
1.84
1.02
1.2
1.3
—
—
—
0
0
31
221
1.41
1.02
1.1
1.2
—
—
—
0
0
58
456
1.28
1.02
2.1
1.6
4769.26
1310.68
u/l
0.34
14
141
603
6415
0.92
1.00
3.4
3.7
7.11
7.70
mg/mmol
0.12
351
4001
21
139
1.51
1.00
1.1
1.2
—
—
—
0
0
51
396
1.29
0.99
1.2
1.5
136.63
121.94
u/ml
—
8
89
9
49
1.84
0.98
1.0
1.1
—
—
—
0
0
26
181
1.44
0.98
1.3
1.1
—
—
—
0
0
26
181
1.44
0.98
1.3
1.1
—
—
—
0
0
26
181
1.44
0.98
1.3
1.1
—
—
—
0
0
63
504
1.26
0.97
1.5
2.3
0.00
0.00
g/l
-0.00
56
472
69
559
1.24
0.96
1.3
1.3
—
—
—
0
0
0
31
0.00
0.96
0.0
1.0
—
—
—
0
0
81
668
1.22
0.96
2.2
2.5
189.76
436.36
ug/l
2.17
75
620
14
85
1.65
0.94
1.8
1.6
—
—
—
0
0
16
101
1.59
0.93
1.1
1.0
—
—
—
0
0
30
217
1.39
0.93
2.0
1.9
—
—
—
0
0
232
2087
1.12
0.92
1.7
1.7
—
—
—
0
0
85
708
1.21
0.92
1.5
2.2
—
—
—
0
0
85
708
1.21
0.92
1.5
2.2
6.96
7.31
g/l
1.05
78
657
85
708
1.21
0.92
1.5
2.2
3.53
3.65
g/l
0.46
78
657
37
278
1.34
0.92
1.4
1.5
288.50
340.14
pmol/l
0.74
30
250
41
314
1.31
0.90
5.9
5.7
401.22
362.61
umol/l
1.23
36
281
65
795
0.81
0.90
2.2
1.9
—
—
—
0
0
6
29
2.07
0.89
1.3
4.4
40.00
43.71
umol/l
—
6
22
26
185
1.41
0.89
1.2
1.1
—
—
—
0
0
55
439
1.26
0.89
1.1
1.1
1.02
1.69
u/ml
0.44
22
210
62
502
1.24
0.88
1.5
2.3
0.00
0.00
g/l
-0.00
55
471
31
228
1.36
0.88
1.6
1.4
0.99
1.00
g/l
0.06
31
228
49
386
1.27
0.88
1.1
1.1
3.44
4.26
u/ml
0.22
20
171
38
289
1.32
0.88
1.8
1.7
—
—
—
0
0
8
43
1.86
0.87
1.0
1.0
—
—
—
0
0
37
281
1.32
0.86
1.2
1.1
—
—
—
0
0
31
229
1.36
0.86
2.0
2.3
34.16
32.50
pg
1.47
31
229
55
441
1.25
0.86
9.1
6.6
296.55
443.04
iu/ml
0.37
11
69
49
388
1.27
0.85
1.2
1.2
6.26
3.47
u/ml
0.27
19
115
49
388
1.27
0.85
1.5
1.7
—
—
—
0
0
132
1154
1.15
0.83
1.1
1.0
—
—
—
0
0
16
105
1.53
0.81
1.2
1.2
—
—
—
0
0
12
73
1.65
0.81
5.4
3.4
—
—
—
0
0
24
172
1.40
0.81
1.3
1.6
77.75
76.00
umol/l
0.18
24
172
159
1413
1.13
0.80
1.7
1.7
—
—
—
0
0
9
149
0.60
0.79
1.3
1.1
—
—
—
0
0
73
611
1.20
0.78
1.5
2.4
0.90
0.92
g/l
0.01
65
548
0
26
0.00
0.78
0.0
1.3
—
—
—
0
0
0
26
0.00
0.78
0.0
1.1
—
0.35
—
0
13
0
26
0.00
0.78
0.0
2.4
—
0.69
—
0
26
44
349
1.27
0.77
1.1
1.1
0.80
1.55
u/ml
0.51
17
153
67
558
1.21
0.76
1.8
1.9
4.41
4.39
iu/l
0.00
15
210
53
431
1.23
0.76
2.7
2.3
134.07
130.88
g/l
0.32
43
308
9
53
1.70
0.75
1.0
1.2
99.44
101.72
%
—
9
53
9
53
1.70
0.75
1.1
1.1
—
—
—
0
0
233
2128
1.10
0.74
1.7
1.8
—
—
—
0
0
143
1271
1.13
0.73
10.2
10.0
0.71
0.67
%
0.57
143
1261
72
607
1.19
0.73
3.2
4.2
3.91
3.87
mmol/l
0.33
72
601
5
25
2.00
0.72
1.4
1.1
—
—
—
0
0
52
426
1.23
0.71
1.6
1.6
—
—
—
0
0
144
1285
1.13
0.70
10.2
10.0
93.80
94.09
%
0.17
144
1278
7
41
1.71
0.70
1.7
1.8
17.89
18.48
umol/l
—
7
41
11
169
0.65
0.69
1.5
1.3
—
—
—
0
0
143
1278
1.13
0.68
10.0
9.8
1.44
1.38
%
0.22
143
1269
70
595
1.18
0.66
1.3
1.4
—
—
—
0
0
46
375
1.23
0.66
1.1
1.1
0.53
1.26
u/ml
0.89
18
146
16
111
1.44
0.66
2.0
2.0
18.80
91.61
ug/l
0.52
16
99
10
62
1.62
0.65
1.1
1.1
1.25
11.42
u/ml
—
5
34
332
3105
1.08
0.64
1.9
1.8
1.33
1.43
%
1.62
301
2777
26
198
1.32
0.64
1.2
1.3
1.59
1.57
g/l
0.14
26
198
83
719
1.16
0.63
1.9
2.0
93.26
93.35
%
0.01
77
686
8
50
1.60
0.61
1.0
1.2
—
—
—
0
0
619
6463
0.94
0.61
2.8
3.1
7.76
7.81
mmol/l
0.10
530
5534
17
122
1.40
0.60
1.3
1.3
—
—
—
0
0
162
1473
1.11
0.59
2.6
2.8
75.67
72.74
e9/l
0.35
116
1115
189
1733
1.10
0.59
9.5
8.0
7.95
8.79
mmol/l
1.36
182
1664
78
678
1.16
0.58
1.5
1.6
333.67
303.49
mu/l
0.24
69
616
131
1179
1.12
0.58
1.5
1.4
—
—
—
0
0
0
23
0.00
0.58
0.0
2.2
—
—
—
0
0
29
228
1.27
0.58
5.1
4.9
220.50
78.38
u/ml
—
8
64
24
184
1.31
0.57
1.3
1.2
0.26
0.60
u/ml
0.67
12
98
588
6129
0.95
0.55
2.8
3.1
635.28
396.01
mg/l
0.42
353
3808
25
195
1.28
0.54
2.5
2.3
4.05
4.01
mmol/l
0.15
25
190
25
195
1.28
0.54
2.5
2.3
107.08
105.48
mmol/l
0.82
25
190
36
294
1.23
0.54
3.4
2.5
3.81
97.63
u/ml
0.99
36
289
43
358
1.20
0.54
1.1
1.1
2.18
3.73
u/ml
0.92
18
185
62
717
0.86
0.53
1.8
1.7
—
—
—
0
0
36
295
1.22
0.53
1.6
1.6
—
—
—
0
0
45
379
1.19
0.51
1.6
1.6
—
—
—
0
0
18
135
1.34
0.51
1.3
1.3
135.18
135.01
nmol/l
0.00
18
135
25
197
1.27
0.51
1.7
2.6
—
—
—
0
0
6
41
1.46
0.50
9.0
2.1
—
—
—
0
0
6
41
1.46
0.50
1.3
1.6
—
—
—
0
0
47
399
1.18
0.49
1.0
1.1
—
—
—
0
0
26
207
1.26
0.49
1.5
1.6
—
—
—
0
0
20
154
1.30
0.48
1.6
1.2
—
—
—
0
0
20
154
1.30
0.48
1.6
1.2
—
—
—
0
0
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
7
46
1.52
0.48
1.1
1.2
—
78.00
—
0
15
22
172
1.28
0.48
1.0
1.2
—
—
—
0
0
97
873
1.12
0.46
3.6
3.5
24.23
24.27
mmol/l
0.05
97
857
56
486
1.16
0.46
1.4
1.3
—
—
—
0
0
20
156
1.28
0.45
2.4
2.9
40.05
42.69
%
0.28
13
84
69
613
1.13
0.42
1.3
1.2
—
—
—
0
0
5
32
1.56
0.42
1.2
1.7
52.94
93.77
ng/l
—
5
32
100
1099
0.91
0.42
9.8
11.0
—
—
—
0
0
331
3152
1.06
0.42
2.7
2.4
14.96
13.79
umol/l
2.14
305
2962
24
194
1.24
0.42
5.7
4.3
—
—
—
0
0
16
206
0.78
0.41
2.2
1.8
—
—
—
0
0
16
206
0.78
0.41
2.2
1.8
—
—
—
0
0
16
206
0.78
0.41
2.2
1.8
—
—
—
0
0
8
59
1.36
0.41
1.0
1.1
—
—
—
0
0
38
324
1.18
0.40
1.1
1.1
7.78
2.74
u/ml
0.52
11
136
16
205
0.78
0.40
1.6
1.3
—
—
—
0
0
85
768
1.11
0.40
3.3
5.6
1.61
1.71
%
0.44
78
718
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
74
664
1.12
0.39
1.5
1.2
10.79
5.45
u/ml
0.41
14
107
13
97
1.34
0.39
1.8
1.8
2.86
7.50
ug/l
—
6
66
211
1991
1.06
0.37
2.6
2.7
1.83
1.81
%
0.06
187
1789
9
69
1.31
0.37
1.6
1.2
—
—
—
0
0
31
262
1.19
0.37
1.1
1.1
0.06
0.21
u/ml
—
5
69
31
262
1.19
0.37
1.1
1.1
—
—
—
0
0
19
152
1.25
0.37
1.7
1.8
—
—
—
0
0
78
707
1.11
0.36
3.1
4.1
1.30
1.35
mmol/l
0.18
78
697
6
43
1.40
0.35
1.0
1.3
—
—
—
0
0
206
2175
0.94
0.34
3.7
4.2
62.12
21.09
ug/l
0.44
160
1743
20
163
1.23
0.34
2.3
1.8
4.77
3.75
mg/l
0.28
20
157
15
118
1.27
0.33
1.1
1.1
—
—
—
0
0
13
166
0.78
0.33
1.6
1.5
4255.00
57624.35
e6/l
—
6
96
10
74
1.35
0.32
1.4
1.7
—
—
—
0
0
41
360
1.14
0.32
3.8
2.7
1.36
1.51
mmol/l
0.91
41
345
57
512
1.12
0.32
2.0
1.8
—
—
—
0
0
176
1663
1.06
0.31
3.8
3.5
1.85
2.00
mmol/l
0.21
159
1392
72
656
1.10
0.31
1.5
1.2
2.22
6.89
u/ml
—
8
63
85
781
1.09
0.31
1.9
1.7
1.60
1.57
g/l
0.08
69
680
25
211
1.19
0.31
1.3
1.5
—
—
—
0
0
10
76
1.32
0.28
1.9
1.9
—
—
—
0
0
8
62
1.29
0.28
1.3
1.7
—
—
—
0
0
25
214
1.17
0.27
2.0
1.5
35.92
34.45
%
0.06
12
126
38
337
1.13
0.27
4.0
2.8
7.43
7.31
mmol/l
0.09
38
326
29
252
1.15
0.27
1.8
1.6
—
—
—
0
0
29
252
1.15
0.27
1.8
1.6
—
—
—
0
0
196
2053
0.95
0.26
2.3
2.3
0.22
0.22
g/l
0.11
187
1937
14
113
1.24
0.26
1.2
1.8
—
—
—
0
0
14
113
1.24
0.26
2.0
1.7
—
—
—
0
0
199
1903
1.05
0.25
8.5
8.9
124.85
123.01
g/l
0.69
194
1851
9
73
1.23
0.25
1.1
1.3
—
—
—
0
0
27
235
1.15
0.25
3.7
2.3
21.20
25.12
mg/l
—
10
62
55
502
1.10
0.25
2.1
1.8
—
—
—
0
0
14
114
1.23
0.25
2.0
1.7
—
—
—
0
0
9
76
1.18
0.24
1.1
1.1
—
—
—
0
0
47
427
1.10
0.23
1.3
1.2
308.11
293.24
u/ml
0.09
27
267
47
428
1.10
0.23
3.5
3.3
27.76
22.73
mg/l
0.39
27
253
5
39
1.28
0.23
1.0
1.7
—
—
—
0
0
5
40
1.25
0.22
1.0
1.2
—
—
—
0
0
7
94
0.74
0.22
3.7
2.3
—
—
—
0
0
7
94
0.74
0.22
3.7
2.3
—
—
—
0
0
7
95
0.74
0.22
3.7
2.3
—
—
—
0
0
42
381
1.10
0.22
1.3
1.2
3.83
5.61
u/ml
0.49
18
147
42
462
0.91
0.22
4.0
7.7
104.68
105.21
mmol/l
0.26
37
414
5
41
1.22
0.22
1.2
1.1
—
—
—
0
0
233
2248
1.04
0.21
7.9
8.1
0.85
1.11
mmol/l
0.55
191
1810
26
229
1.14
0.21
1.2
1.2
55.77
64.26
u/l
0.63
26
209
0
11
0.00
0.21
0.0
1.0
—
97.00
—
0
6
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
6.2
—
393.92
—
0
12
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
233
2251
1.04
0.20
7.9
8.0
13.06
12.61
kpa
0.56
222
2167
233
2251
1.04
0.20
7.9
8.1
5.11
5.10
kpa
0.05
222
2166
17
145
1.17
0.20
1.1
1.1
—
—
—
0
0
12
99
1.21
0.19
1.2
1.3
5.78
6.12
mmol/l
0.60
12
94
12
99
1.21
0.19
1.0
1.1
163.85
194.88
iu/ml
0.24
12
99
41
378
1.09
0.17
1.4
1.5
—
—
—
0
0
515
5059
1.02
0.16
2.3
2.3
—
—
—
0
0
82
779
1.05
0.16
4.6
3.6
48.82
51.12
%
0.36
82
768
10
119
0.84
0.15
1.2
1.7
1.70
2.11
u/field
—
10
91
12
102
1.18
0.15
1.1
1.1
1417.42
1580.38
miu/ml
0.23
12
102
296
2892
1.03
0.15
2.9
2.4
2.34
2.36
g/l
0.21
271
2701
130
1252
1.04
0.15
5.5
7.2
25.11
24.67
mmol/l
0.96
125
1192
58
547
1.06
0.14
1.8
3.6
38.90
66.31
mg/l
1.02
41
437
313
3063
1.02
0.14
1.8
1.8
—
—
—
0
0
276
2698
1.03
0.14
3.0
2.5
25.09
23.81
%
0.83
234
2327
8
98
0.82
0.13
2.5
2.1
—
186.23
—
0
22
11
94
1.17
0.13
1.1
1.2
—
—
—
0
0
56
530
1.06
0.13
1.7
3.6
1.29
2.61
ratio
—
5
50
14
123
1.14
0.12
1.4
1.4
—
—
—
0
0
39
365
1.07
0.12
2.1
1.8
—
—
—
0
0
39
365
1.07
0.12
2.1
1.8
—
—
—
0
0
49
463
1.06
0.12
1.5
1.4
—
—
—
0
0
207
2022
1.03
0.12
8.3
8.5
95.96
95.95
%
0.01
202
1948
16
143
1.12
0.11
1.4
1.4
—
—
—
0
0
17
188
0.90
0.11
1.5
1.4
1546.30
2945.07
e6/l
—
10
130
5
45
1.11
0.09
1.4
1.2
—
—
—
0
0
10
114
0.88
0.09
2.9
2.1
—
—
—
0
0
10
114
0.88
0.09
2.9
2.1
—
—
—
0
0
118
1149
1.03
0.09
3.3
3.3
2.02
1.75
mmol/l
0.36
94
883
57
547
1.04
0.09
1.8
3.6
36.31
30.27
mg/l
0.31
41
439
15
165
0.91
0.08
1.1
1.0
—
—
—
0
0
22
204
1.08
0.08
1.3
1.2
—
—
—
0
0
24
257
0.93
0.08
1.7
1.5
—
—
—
0
0
5
60
0.83
0.08
1.2
4.4
—
—
—
0
0
5
60
0.83
0.08
1.2
4.4
—
—
—
0
0
39
372
1.05
0.07
2.3
1.9
—
—
—
0
0
104
1066
0.97
0.07
1.6
1.6
—
—
—
0
0
7
84
0.83
0.07
2.3
2.4
0.71
0.90
ug/l
—
7
77
9
84
1.07
0.07
1.6
1.4
—
—
—
0
0
9
84
1.07
0.07
1.6
1.4
—
—
—
0
0
24
255
0.94
0.07
1.7
1.5
—
—
—
0
0
9
85
1.06
0.07
1.1
1.7
—
—
—
0
0
50
482
1.04
0.06
2.4
2.2
0.80
0.85
nmol/l
0.26
44
415
9
102
0.88
0.06
3.3
3.6
—
—
—
0
0
9
102
0.88
0.06
1.6
1.4
—
—
—
0
0
9
104
0.86
0.06
1.6
1.4
—
—
—
0
0
24
254
0.94
0.06
1.7
1.5
—
—
—
0
0
24
254
0.94
0.06
1.7
1.5
—
—
—
0
0
24
254
0.94
0.06
1.7
1.5
—
—
—
0
0
21
223
0.94
0.06
1.5
1.3
4384.45
99223.11
e6/l
1.37
11
152
14
129
1.09
0.05
2.0
1.7
—
—
—
0
0
53
546
0.97
0.05
1.6
1.6
6163.29
11700.74
e6/l
0.76
35
398
18
169
1.07
0.05
2.1
1.8
—
—
—
0
0
74
756
0.98
0.04
3.0
3.4
24.79
24.96
mmol/l
0.20
67
707
34
328
1.04
0.04
1.6
1.5
—
—
—
0
0
75
764
0.98
0.03
3.0
3.7
162.13
1994.62
u/ml
0.79
66
657
47
458
1.03
0.03
1.2
1.2
—
—
—
0
0
39
380
1.03
0.02
1.3
1.1
—
—
—
0
0
41
419
0.98
0.02
3.7
3.6
65.11
1021.66
u/ml
0.95
34
398
50
509
0.98
0.02
1.6
1.2
1.40
3.51
u/ml
—
5
39
30
292
1.03
0.02
1.6
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
13
123
1.06
0.01
1.2
1.1
—
—
—
0
0
112
1128
0.99
0.01
1.6
1.4
—
—
—
0
0
12
114
1.05
0.00
1.3
1.3
—
—
—
0
0
12
114
1.05
0.00
1.3
1.3
—
—
—
0
0
12
114
1.05
0.00
1.3
1.3
—
—
—
0
0
12
114
1.05
0.00
1.3
1.3
—
—
—
0
0
36
354
1.02
0.00
1.1
1.2
—
—
—
0
0
76
754
1.01
0.00
1.8
2.1
4.06
1.95
ug/l
0.32
67
687
13
125
1.04
0.00
3.9
2.7
43776.92
41020.38
ug/l
0.51
13
125
13
135
0.96
0.00
1.5
1.6
14.46
6.42
u/l
0.97
13
112
12
119
1.01
0.00
1.3
1.4
—
—
—
0
0
25
245
1.02
0.00
2.4
1.9
—
—
—
0
0
14
139
1.01
0.00
1.0
1.3
9.16
9.41
mmol/l
0.09
14
134
25
255
0.98
0.00
2.3
2.3
—
—
—
0
0
26
259
1.00
0.00
2.3
1.8
—
—
—
0
0
26
261
1.00
0.00
1.7
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
60
599
1.00
0.00
5.0
2.8
0.46
0.33
u/ml
1.41
28
332
10
104
0.96
0.00
1.0
1.1
—
—
—
0
0
13
132
0.98
0.00
1.1
1.2
14.00
20.04
u/l
0.55
13
111
17
172
0.99
0.00
1.2
1.3
—
—
—
0
0
41
413
0.99
0.00
1.8
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
5.0
—
—
—
0
0
6
67
0.90
0.00
1.0
1.1
—
—
—
0
0
8
82
0.98
-0.00
1.6
1.1
—
—
—
0
0
7
69
1.01
-0.00
1.3
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.0
—
8.31
—
0
7
6
63
0.95
-0.00
1.0
1.1
—
—
—
0
0
9
95
0.95
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
2.43
—
0
7
71
710
1.00
-0.00
1.3
1.3
216.69
206.14
miu/ml
0.09
26
343
8
82
0.98
-0.00
1.4
1.3
115.88
106.69
%
—
8
72
0
9
0.00
-0.00
0.0
4.3
—
—
—
0
0
7
71
0.99
-0.00
1.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
14.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
1475.50
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
64
0.94
-0.00
1.0
1.1
—
—
—
0
0
8
84
0.95
-0.00
1.6
1.5
—
—
—
0
0
8
81
0.99
-0.00
1.9
1.6
8.41
8.32
ug/l
—
8
81
6
59
1.02
-0.00
1.2
1.2
—
—
—
0
0
8
84
0.95
-0.00
1.6
1.5
—
—
—
0
0
6
69
0.87
-0.00
1.0
1.0
—
—
—
0
0
8
83
0.96
-0.00
1.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
1.2
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_PRESBYOPIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PRESBYOPIA | 1.379 [1.18, 1.61] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.285 |
During the follow-up period (1.1.1998 — 31.12.2019), 328 out of 3648 females with H7_PRESBYOPIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PRESBYOPIA | 1.398 [1.2, 1.63] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.031 |
During the follow-up period (1.1.1998 — 31.12.2019), 432 out of 2916 males with H7_PRESBYOPIA died.
Mortality risk
Mortality risk for people of age
years, who have H7_PRESBYOPIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.137% | 0.295% |
| 5 | 0.843% | 1.703% |
| 10 | 2.094% | 4.247% |
| 15 | 4.011% | 8.649% |
| 20 | 7.218% | 14.601% |
Relationships between endpoints
↥Index endpoint: H7_PRESBYOPIA – Presbyopia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data