No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2399 |
4. Check minimum number of eventsNone |
2399 |
5. Include endpointsNone |
2399 |
6. Filter based on genotype QC (FinnGen only) |
2399 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H52
- Name in latin
- Presbyopia
Similar endpoints
↥List of similar endpoints to
Presbyopia
based on the number of shared cases.
Similar with more cases:
- Disorders of refraction and accommodation
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12798 | 7185 | 5554 |
| Only index persons | 11977 | 6753 | 5224 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.18 | 0.21 | 0.16 |
| Only index persons | 0.23 | 0.25 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 53.91 | 54.12 | 53.65 |
| Only index persons | 53.71 | 53.84 | 53.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2399 | 1524 | 875 |
| Unadjusted period prevalence (%) | 0.47 | 0.52 | 0.39 |
| Median age at first event (years) | 54.84 | 54.35 | 55.71 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2029
- Matched controls
- 20289
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H52.4
ICD-10 Finland
Presbyopia
1710.1
323.0
1887
151
H52.0
ICD-10 Finland
Hypermetropia
78.4
198.7
224
32
H52.1
ICD-10 Finland
Myopia
28.7
150.4
207
80
37002
ICD-8 Finland
Refractive errors, Myopia
+∞
149.9
142
*
H52.2
ICD-10 Finland
Astigmatism
51.0
121.8
147
31
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.7
59.6
489
2134
CGD20
NOMESCO Finland
Laser-assisted in situ keratomileusis
305.8
58.6
59
*
CJE40
NOMESCO Finland
Phakoemulsification with implantation of skleralt fixed artificial lens in posterior chamber
305.8
58.6
59
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.2
57.8
901
5436
XCK00
NOMESCO Finland
Perimetry
3.6
38.2
184
546
H50.52
ICD-10 Finland
Exophoria
41.7
33.1
41
10
H04.10
ICD-10 Finland
Dry eye syndrome
2.6
32.5
267
1130
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
32.4
31
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.9
31.3
633
3969
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
27.9
24.5
33
12
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.4
21.3
188
823
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.3
21.3
215
1004
N03AX12
ATC
gabapentin; oral
1.9
19.9
331
1898
H53.2
ICD-10 Finland
Diplopia
4.3
19.4
73
175
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
18.4
303
1728
R51.80
ICD-10 Finland
Headache
1.9
18.3
298
1690
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
17.7
17
*
ZXA10
NOMESCO Finland
Bilateral
1.8
17.6
337
2019
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
17.2
147
631
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.1
14.9
167
814
H50.1
ICD-10 Finland
Divergent concomitant strabismus
57.1
14.8
17
*
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
14.6
14
*
H50.31
ICD-10 Finland
Intermittent exotropia
151.0
14.5
15
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.2
14.2
151
722
N02AX02
ATC
tramadol; systemic, rectal
1.5
14.1
807
6327
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.1
13.8
164
824
A02BC05
ATC
esomeprazole; systemic
1.4
13.4
780
6115
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
13.2
394
2664
AA1AD
NOMESCO Finland
CT of head and brain
1.6
12.7
394
2689
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
12.1
635
4855
H25.0
ICD-10 Finland
Senile incipient cataract
2.5
12.0
96
398
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.0
11.8
159
836
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
11.5
11
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
11.1
291
1894
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.9
10.9
168
933
37600
ICD-8 Finland
Detachment of retina, Primaria
28.2
10.7
14
5
N03AX16
ATC
pregabalin; oral
1.5
10.7
441
3199
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.3
10.7
100
454
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
10.6
191
1116
R42
ICD-10 Finland
Dizziness and giddiness
1.5
10.6
342
2347
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.3
10.5
52
162
H52.5
ICD-10 Finland
Disorders of accommodation
+∞
10.4
10
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
10.3
166
935
H50.51
ICD-10 Finland
Esophoria
40.3
10.0
12
*
H26.4
ICD-10 Finland
After-cataract
2.1
9.9
109
532
G44.2
ICD-10 Finland
Tension-type headache
1.6
9.6
241
1550
R06.0
ICD-10 Finland
Dyspnoea
1.5
9.5
394
2852
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
+∞
9.4
9
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
9.4
9
*
A02BC03
ATC
lansoprazole; oral
1.4
9.2
526
4048
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
9.2
385
2793
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
9.1
520
3999
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
9.1
711
5768
E0000UV
ATC
NA
1.4
8.9
675
5442
R20.2
ICD-10 Finland
Paraesthesia of skin
1.9
8.8
126
682
M03BX02
ATC
tizanidine; oral
1.3
8.7
1269
11281
H54.7
ICD-10 Finland
Unspecified visual loss
7.2
8.7
20
28
N02BE01
ATC
paracetamol; systemic, rectal
1.4
8.7
1652
15333
K30
ICD-10 Finland
Functional dyspepsia
1.7
8.6
186
1147
A02BC02
ATC
pantoprazole; systemic
1.3
8.6
1199
10581
H50.2
ICD-10 Finland
Vertical strabismus
27.6
8.5
11
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
8.4
854
7186
G35
ICD-10 Finland
Multiple sclerosis
3.2
8.4
42
133
R03AC03
ATC
terbutaline; inhalant
1.6
8.4
251
1689
H02AB06
ATC
prednisolone; systemic
1.3
8.3
837
7030
UJF32
NOMESCO Finland
Coloscopy
1.4
8.3
428
3226
H46
ICD-10 Finland
Optic neuritis
4.8
8.2
26
55
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
8.1
310
2206
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
4.0
8.1
30
75
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
7.8
455
3498
N06AX16
ATC
venlafaxine; oral
1.5
7.8
257
1768
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
7.6
402
3035
R06AX27
ATC
desloratadine; oral
1.4
7.5
499
3919
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
7.5
181
1152
N06AX21
ATC
duloxetine; oral
1.6
7.5
210
1391
M25.5
ICD-10 Finland
Pain in joint
1.3
7.4
522
4142
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
7.3
7
*
J02AC01
ATC
fluconazole; systemic
1.3
7.2
782
6600
M79.6
ICD-10 Finland
Pain in limb
1.3
7.2
618
5048
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.4
7.2
378
2850
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.9
7.2
105
576
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
7.0
240
1664
N06AA09
ATC
amitriptyline; systemic
1.6
6.9
171
1098
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.9
456
3576
F51.0
ICD-10 Finland
Nonorganic insomnia
1.5
6.9
226
1552
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.4
6.8
55
235
H53.0
ICD-10 Finland
Amblyopia ex anopsia
6.1
6.8
17
28
37602
ICD-8 Finland
Detachment of retina, Foramen, ruptura retinae
40.2
6.8
8
*
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
40.2
6.8
8
*
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.7
370
2814
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.6
6.7
156
987
H02.3
ICD-10 Finland
Blepharochalasis
1.8
6.7
103
577
UKC02
NOMESCO Finland
Cystoscopy
1.5
6.6
217
1492
SPAT1312
SPAT
General health counselling
1.3
6.6
482
3836
N06AX11
ATC
mirtazapine; oral
1.3
6.4
558
4551
L04AX01
ATC
azathioprine; systemic
2.0
6.4
77
395
M54.2
ICD-10 Finland
Cervicalgia
1.7
6.4
133
816
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
3.7
6.3
25
68
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.3
6.3
52
227
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
2.9
6.3
36
126
R35
ICD-10 Finland
Polyuria
1.8
6.2
92
508
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.8
6.2
108
627
N03AF02
ATC
oxcarbazepine; oral
2.3
6.2
52
228
R01AD12
ATC
fluticasone furoate; nasal
1.3
6.2
527
4281
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
1.9
6.2
83
440
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
6.2
184
1237
A98
ICPC
Health maint/preventive medicine
1.7
6.2
1931
18715
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.1
269
1961
109
Kela drug reimbursment
Multiple sclerosis
3.3
6.1
28
86
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
6.0
163
1071
WX408
NOMESCO Finland
General anesthesy, balanced
1.3
6.0
459
3669
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1030
8265
1.43
15.88
2.5
2.2
78.9
76.7
nmol/l
1.69
956
7586
1712
15107
1.47
15.36
4.5
4.0
10.6
11.3
mm/h
1.35
1597
14174
2043
18771
1.60
14.50
5.2
4.7
1.8
2.0
mu/l
1.18
1917
17472
1140
9411
1.40
14.49
3.9
3.4
0.0
0.0
estimate
0.00
214
1659
1150
9539
1.39
14.05
4.0
3.4
0.0
0.0
estimate
1.72
213
1642
1363
11638
1.40
13.99
10.0
9.5
3.8
4.0
e9/l
2.06
1211
10251
747
5783
1.42
13.48
2.2
2.1
174.7
212.9
u/l
0.57
702
5474
1136
9448
1.38
13.44
5.2
4.6
0.0
0.0
estimate
0.80
215
1704
404
2793
1.54
12.89
1.9
2.2
29.7
29.7
s
0.01
394
2714
1768
15890
1.43
12.81
4.4
4.0
14.5
14.6
pmol/l
0.70
1638
14735
1391
12203
1.33
10.47
4.7
3.9
7179.1
1407.2
e6/l
0.56
13
155
466
3447
1.44
10.43
1.6
1.5
—
—
—
0
0
900
7416
1.34
10.43
1.9
1.9
98.0
97.1
pmol/l
0.25
458
3893
1002
8415
1.33
10.09
3.0
2.7
111.5
125.9
ug/l
1.47
949
7923
631
4943
1.38
10.08
4.3
3.8
0.0
0.0
estimate
1.15
207
1653
634
5019
1.36
9.36
2.9
2.9
0.4
0.4
e6/l
0.02
485
3717
1848
17056
1.36
9.04
17.6
15.5
13.6
13.7
%
1.11
1811
16700
1704
15541
1.33
9.00
8.3
7.7
74.9
77.3
u/l
1.15
1615
14747
1091
9371
1.30
8.98
6.7
6.6
1.2
1.2
mmol/l
0.26
925
7983
1107
9554
1.29
8.68
6.7
6.0
56.1
56.6
%
0.70
1053
8989
993
8472
1.29
8.43
5.9
5.9
1.2
1.2
mmol/l
0.46
910
7754
581
4609
1.34
8.32
1.8
1.7
1.0
1.0
mg/l
0.10
445
3520
672
5470
1.32
8.01
3.1
3.0
152.6
100.2
e6/l
0.29
522
4144
411
3123
1.38
7.69
2.6
2.5
1.0
1.0
e6/l
0.08
246
1721
1111
9688
1.27
7.69
7.1
6.2
29.4
28.8
%
1.23
1053
9078
323
2356
1.43
7.66
5.9
6.2
—
—
—
0
0
477
3720
1.35
7.57
2.4
2.5
4.9
5.8
e6/l
0.98
424
3265
868
7397
1.27
7.08
4.1
3.5
—
—
—
0
0
1168
10329
1.25
6.89
6.3
6.5
11.2
11.1
umol/l
0.12
1114
9852
746
6268
1.28
6.77
2.6
2.6
57.3
57.5
u/l
0.06
680
5844
206
1411
1.50
6.75
1.3
1.3
135.7
214.4
u/ml
1.50
192
1316
2276
22040
1.64
6.63
11.8
10.2
26.4
27.3
u/l
1.84
2217
21461
83
451
1.87
6.62
1.3
1.3
17.9
23.8
e6/l
0.18
59
336
83
452
1.87
6.57
1.3
1.4
1790.1
1895.7
e6/l
0.02
61
357
328
2467
1.38
6.49
2.5
2.3
102.8
125.5
ug/g
0.76
263
1985
2130
20370
1.41
6.42
14.6
12.9
21.3
21.7
mg/l
0.25
1700
15949
846
7256
1.26
6.37
3.3
3.2
105.8
45.9
ng/l
0.38
503
4512
30
108
2.80
6.32
2.0
2.6
638.2
961.8
u/ml
0.64
30
108
422
3325
1.33
6.15
2.7
3.0
2.4
2.4
mmol/l
0.16
375
2918
942
8206
1.24
6.11
5.0
4.8
36.4
36.1
g/l
1.08
867
7699
1486
13606
1.24
6.04
3.0
2.9
—
—
—
0
0
444
3532
1.32
6.04
1.5
1.4
—
—
—
0
0
759
6463
1.26
6.01
3.3
3.5
2.4
2.4
mmol/l
0.12
666
5762
135
868
1.59
5.91
1.8
1.7
4.9
3.9
mg/l
0.25
99
621
126
800
1.61
5.82
1.4
1.4
—
—
—
0
0
2197
21191
1.44
5.68
5.1
4.8
2.9
2.9
mmol/l
0.33
2057
19898
38
163
2.35
5.66
1.1
1.1
246.6
279.7
mg/l
0.68
30
145
2189
21107
1.42
5.60
15.6
14.2
3.9
4.0
mmol/l
1.42
2144
20632
89
523
1.73
5.53
1.3
1.2
508.1
536.9
mg/l
0.30
82
495
488
3975
1.29
5.52
1.5
1.5
20.8
21.0
nmol/l
0.17
426
3460
133
867
1.57
5.51
1.4
1.2
0.7
1.3
u/ml
0.39
12
73
527
4338
1.28
5.48
2.2
2.1
2.8
3.0
mg/l
1.14
442
3739
2169
20903
1.39
5.35
4.7
4.4
4.9
4.8
mmol/l
0.29
2034
19744
2180
21027
1.40
5.35
15.5
14.1
139.8
139.8
mmol/l
0.25
2143
20580
38
169
2.27
5.24
1.2
1.2
34.1
39.8
mg/l
0.55
27
145
2336
22880
1.80
5.13
21.9
19.0
137.1
136.8
g/l
0.63
2318
22628
2334
22860
1.77
5.05
21.8
18.9
254.6
256.9
e9/l
0.99
2308
22392
2335
22875
1.78
5.01
21.8
18.9
4.5
4.5
e12/l
0.51
2303
22347
2335
22877
1.78
4.98
21.8
18.9
6.4
6.6
e9/l
2.43
2307
22348
1993
19014
1.28
4.96
15.9
13.5
40.7
40.3
%
1.18
1511
14600
130
871
1.52
4.80
1.6
1.5
—
—
—
0
0
101
644
1.59
4.64
1.9
1.7
—
—
—
0
0
485
4030
1.26
4.59
4.4
3.8
1.0
1.0
kg/l
0.55
55
541
2048
19650
1.29
4.57
13.1
11.6
83.4
83.5
ml/min/173m2
0.12
1745
16461
197
1444
1.40
4.57
2.6
2.3
13.4
13.0
nmol/l
0.35
172
1302
212
1577
1.38
4.50
2.6
2.7
10.3
10.5
g/l
0.37
192
1447
2153
20807
1.34
4.49
4.6
4.3
1.5
1.5
mmol/l
4.72
2018
19565
358
2878
1.29
4.45
2.8
2.7
2.9
2.7
e6/l
0.10
194
1491
77
464
1.68
4.44
1.2
1.2
3.7
3.7
mmol/l
0.22
70
433
1230
11250
1.19
4.33
4.6
4.7
6.5
6.7
mmol/l
3.29
1166
10635
51
274
1.88
4.32
1.5
1.5
—
—
—
0
0
244
1873
1.34
4.24
3.3
3.1
—
—
—
0
0
67
396
1.71
4.16
3.8
3.6
57.8
57.0
%
0.22
67
396
98
640
1.55
4.11
1.9
1.6
126.9
0.5
iu/ml
0.48
26
120
634
5483
1.21
4.07
2.4
2.4
6568.6
3840.1
umol/l
0.76
557
4855
2087
20129
1.28
4.06
4.6
4.3
5.7
5.9
mmol/l
9.16
1934
18723
523
4460
1.22
3.84
1.3
1.2
1.9
1.7
u/ml
0.12
143
1272
95
629
1.53
3.77
1.3
1.3
—
—
—
0
0
561
4828
1.21
3.75
2.6
2.8
567.3
973.1
ng/l
6.96
454
4051
2087
20171
1.27
3.69
4.2
3.9
1.3
1.3
mmol/l
2.49
1944
18869
304
2453
1.27
3.67
5.3
5.8
1.0
1.0
mmol/l
0.56
283
2292
1990
19139
1.23
3.63
5.4
5.3
38.6
39.4
mmol/mol
4.51
1873
18003
218
1686
1.32
3.62
2.3
2.5
67.4
70.0
ml/min/173m2
0.51
91
640
56
331
1.71
3.53
1.4
1.3
—
—
—
0
0
56
331
1.71
3.53
1.4
1.3
—
—
—
0
0
180
1361
1.35
3.50
3.4
3.6
79.5
81.2
ng/l
0.11
154
1208
241
1901
1.30
3.48
2.4
2.2
348.3
365.9
nmol/l
0.80
227
1767
25
114
2.21
3.35
1.0
1.1
1.1
2.6
nmol/l
—
7
23
43
242
1.79
3.23
1.1
1.1
—
—
—
0
0
16
60
2.68
3.22
1.0
1.3
97.9
91.8
%
—
8
31
87
587
1.50
3.21
1.2
1.1
—
—
—
0
0
173
1322
1.33
3.15
1.7
1.7
—
—
—
0
0
637
5624
1.18
3.15
4.4
4.3
2.2
2.2
ug/l
0.01
579
5133
358
2997
1.23
3.13
1.9
1.7
1167.4
1187.6
nmol/l
0.16
255
2328
16
61
2.63
3.13
1.0
1.1
98.2
90.7
%
—
8
31
84
568
1.50
3.08
1.5
1.4
283.0
289.9
ug/g
0.12
50
323
44
254
1.75
3.05
1.3
1.3
—
—
—
0
0
49
292
1.69
3.04
1.5
1.4
0.6
0.6
nmol/l
0.23
49
279
174
1343
1.32
2.97
3.4
3.3
4.4
4.5
pmol/l
0.64
148
1195
15
57
2.64
2.96
5.8
4.2
—
—
—
0
0
1540
14581
1.16
2.93
3.5
3.1
42.7
48.4
u/l
2.16
1447
13784
280
2303
1.24
2.89
2.8
2.8
7.8
7.6
umol/l
0.06
248
2034
63
406
1.57
2.89
1.3
1.4
40.9
33.3
u/l
0.55
45
322
231
1865
1.26
2.81
2.5
2.5
33.5
40.0
u/l
0.97
204
1625
30
158
1.91
2.80
1.2
1.1
—
—
—
0
0
191
1509
1.29
2.77
1.8
2.3
9.3
7.2
ug/l
0.43
172
1359
367
3134
1.20
2.63
3.5
3.6
0.8
0.8
mmol/l
1.34
337
2958
82
572
1.45
2.62
2.5
2.1
9.8
11.9
mg/l
1.50
74
533
189
1503
1.28
2.61
1.7
1.7
—
—
—
0
0
28
149
1.89
2.56
3.0
2.8
536.1
581.3
e6/l
0.17
19
128
24
121
1.99
2.55
1.0
1.1
1.0
1.1
u/l
1.17
11
63
193
1544
1.27
2.55
2.6
2.4
23.8
22.4
au/ml
—
9
102
281
2349
1.22
2.51
1.9
1.8
—
—
—
0
0
26
136
1.92
2.50
1.0
1.0
862.2
766.7
ng/l
0.39
19
93
189
1512
1.27
2.50
3.8
4.0
1.2
1.2
mmol/l
0.10
162
1331
627
5620
1.16
2.50
1.7
1.7
1.3
1.4
mmol/l
2.11
519
4783
80
563
1.44
2.46
2.2
2.5
3.3
3.6
g/l
1.24
75
533
971
8977
1.14
2.46
3.8
3.8
—
—
—
0
0
26
137
1.91
2.46
1.5
1.8
—
—
—
0
0
26
139
1.88
2.36
1.0
1.0
39.2
44.3
ng/l
0.20
19
91
25
132
1.90
2.36
1.0
1.1
9.3
9.7
iu/ml
—
6
38
508
4516
1.16
2.25
4.0
3.7
21.6
21.1
%
0.28
212
1997
176
1417
1.26
2.24
1.4
1.3
38.7
44.1
au/ml
—
7
69
761
6964
1.14
2.21
3.8
3.3
31.7
34.9
u/l
0.62
728
6636
8
24
3.34
2.18
3.0
2.2
—
—
—
0
0
25
136
1.85
2.18
1.0
1.0
351.6
300.6
ng/l
0.24
18
93
79
569
1.40
2.17
1.6
1.7
—
—
—
0
0
84
613
1.38
2.14
1.8
1.7
0.2
0.2
g/l
0.20
79
580
178
1443
1.25
2.14
2.0
2.7
66.6
66.9
g/l
0.19
163
1336
34
204
1.68
2.14
1.1
1.0
—
—
—
0
0
49
323
1.53
2.12
1.3
1.4
0.4
0.3
nmol/l
0.59
32
225
80
581
1.39
2.11
2.5
3.0
—
—
—
0
0
231
1932
1.22
2.09
4.2
4.6
233.1
246.0
u/l
0.80
222
1834
444
3931
1.16
2.08
1.3
1.3
25.2
30.0
iu/ml
0.45
129
1270
35
214
1.64
2.07
1.1
1.1
—
—
—
0
0
76
550
1.39
2.05
2.1
1.7
—
—
—
0
0
188
1542
1.24
2.05
7.8
7.8
1.4
1.3
mmol/l
0.18
181
1492
24
133
1.81
1.99
1.1
1.2
1.0
1.0
ratio
—
9
45
91
687
1.34
1.91
2.0
1.9
—
—
—
0
0
162
1319
1.24
1.91
1.3
1.3
33.2
35.4
iu/l
0.36
141
1141
81
601
1.36
1.90
1.4
2.3
10.5
10.2
g/l
0.29
68
523
165
1350
1.24
1.86
2.7
2.7
173.9
149.6
ng/l
0.28
145
1211
17
86
1.98
1.85
2.5
2.2
57.9
53.4
umol/l
0.19
12
70
423
3768
1.15
1.82
1.3
1.3
10.1
10.7
u/ml
0.07
182
1574
43
287
1.51
1.80
2.0
2.0
1.6
1.7
mmol/l
0.71
43
282
114
898
1.28
1.78
2.7
2.1
40.4
39.5
u/l
0.17
105
808
48
329
1.47
1.77
1.2
1.1
—
—
—
0
0
206
2433
0.83
1.77
4.7
4.3
32.5
31.8
%
0.38
139
1729
6
18
3.34
1.74
1.2
1.0
—
—
—
0
0
8
30
2.67
1.72
3.0
1.9
—
—
—
0
0
53
373
1.43
1.71
3.0
2.7
17.5
16.5
%
1.00
34
199
441
3961
1.14
1.69
1.7
1.6
43935766.0
35027004.9
pmol/l
0.07
371
3386
130
1049
1.25
1.68
7.8
8.3
24.9
24.8
mmol/l
0.06
130
1041
27
164
1.65
1.68
1.4
2.1
13.1
13.8
%
0.09
13
73
6
19
3.16
1.66
1.3
1.8
59.0
39.8
umol/l
—
6
19
18
98
1.84
1.61
1.5
1.5
3.0
6.9
nmol/l
0.73
12
76
24
143
1.69
1.61
3.3
2.8
0.2
0.2
e9/l
0.15
17
127
69
515
1.35
1.60
1.4
2.2
38.3
38.0
g/l
0.13
60
456
41
279
1.48
1.59
5.9
5.5
401.2
357.8
umol/l
1.44
36
248
66
490
1.36
1.59
1.3
1.3
15.6
11.9
u/l
0.59
50
393
395
3537
1.14
1.59
3.6
3.4
418.7
483.9
ng/l
0.16
277
2528
27
167
1.62
1.58
3.2
2.8
1079.1
685.2
e6/l
0.83
11
66
37
248
1.50
1.55
1.4
1.4
294.0
300.7
pmol/l
0.07
26
202
73
553
1.33
1.55
1.2
1.1
4.9
4.2
u/ml
0.07
12
77
68
510
1.34
1.54
1.5
2.2
0.1
0.0
g/l
0.29
61
479
377
3374
1.14
1.53
2.8
2.8
0.7
0.7
ug/l
0.85
218
2057
18
100
1.81
1.53
1.6
1.9
—
—
—
0
0
81
625
1.31
1.52
1.4
2.3
3.0
3.1
g/l
0.44
66
494
48
341
1.42
1.51
1.2
1.2
6.3
3.5
u/ml
0.27
19
105
219
1890
1.17
1.46
1.7
1.7
—
—
—
0
0
7
28
2.50
1.45
1.0
1.0
—
—
—
0
0
7
28
2.50
1.45
1.7
2.4
—
—
—
0
0
7
28
2.50
1.45
1.3
1.0
—
—
—
0
0
5
16
3.13
1.44
21.0
8.7
6.2
5.4
mmol/l
—
5
16
67
508
1.33
1.43
1.3
1.3
—
—
—
0
0
53
391
1.36
1.36
3.7
4.6
5.1
5.0
kpa
0.28
53
384
81
636
1.28
1.36
1.8
2.0
92.5
93.2
%
0.10
71
594
19
112
1.70
1.35
6.8
8.4
28.2
55.1
u/ml
—
5
38
153
1290
1.20
1.35
1.7
1.7
—
—
—
0
0
77
602
1.29
1.34
2.2
2.5
191.1
410.0
ug/l
1.72
71
561
31
453
0.68
1.34
2.4
2.5
236.1
122.8
ug/min
0.54
21
275
48
350
1.38
1.33
1.2
1.5
139.7
122.1
u/ml
—
6
78
62
471
1.32
1.33
1.5
2.3
0.0
0.0
g/l
0.00
55
442
64
489
1.32
1.32
1.5
1.2
57.2
46.0
u/ml
0.29
12
50
25
160
1.57
1.31
1.2
1.1
—
—
—
0
0
170
1452
1.18
1.31
1.2
1.2
119.9
168.4
iu/ml
1.29
60
577
83
658
1.27
1.30
1.4
2.2
7.0
7.3
g/l
0.84
66
511
83
658
1.27
1.30
1.4
2.2
3.6
3.8
g/l
0.64
63
479
83
658
1.27
1.30
1.4
2.2
—
—
—
0
0
52
386
1.35
1.30
1.1
1.1
0.5
1.6
u/ml
1.27
15
144
25
161
1.56
1.28
1.3
1.1
—
—
—
0
0
97
786
1.24
1.27
2.1
2.7
1.4
1.3
%
0.21
97
779
25
162
1.55
1.26
1.3
1.1
—
—
—
0
0
89
716
1.25
1.25
1.8
1.7
—
—
—
0
0
53
398
1.34
1.24
1.2
1.5
—
17.0
—
0
10
73
574
1.28
1.24
1.2
1.1
—
—
—
0
0
183
1582
1.17
1.23
9.1
7.9
8.0
8.8
mmol/l
1.26
176
1520
61
469
1.31
1.22
1.5
2.3
0.0
0.0
g/l
0.00
54
441
51
382
1.34
1.22
1.6
1.5
—
—
—
0
0
5
19
2.63
1.21
1.4
1.1
—
—
—
0
0
31
213
1.46
1.20
2.0
2.3
34.2
32.5
pg
1.44
31
213
29
197
1.48
1.19
1.1
1.2
—
—
—
0
0
35
247
1.42
1.19
1.7
1.6
46.9
57.8
%
0.75
21
151
34
239
1.43
1.18
3.1
3.3
3.1
29.3
nmol/l
0.59
34
233
25
165
1.52
1.17
1.3
1.1
—
—
—
0
0
25
165
1.52
1.17
1.3
1.1
—
—
—
0
0
25
165
1.52
1.17
1.3
1.1
—
—
—
0
0
29
198
1.47
1.17
2.0
1.9
—
—
—
0
0
219
1929
1.15
1.16
1.7
1.8
—
—
—
0
0
0
33
0.00
1.16
0.0
1.0
—
—
—
0
0
53
404
1.32
1.14
9.4
6.5
296.5
450.5
iu/ml
0.35
11
62
72
576
1.26
1.09
1.2
1.1
—
—
—
0
0
10
52
1.93
1.06
1.2
1.3
—
—
—
0
0
12
67
1.80
1.04
5.4
3.6
—
—
—
0
0
86
707
1.22
1.03
1.6
1.8
—
—
—
0
0
25
171
1.47
1.02
1.3
1.4
246.7
215.5
pmol/l
0.05
11
61
9
47
1.92
1.02
1.1
1.1
—
—
—
0
0
9
47
1.92
1.02
1.0
1.1
—
—
—
0
0
9
47
1.92
1.02
1.0
1.1
99.4
100.6
%
—
9
47
71
573
1.25
1.01
1.5
2.4
0.9
0.9
g/l
0.03
63
515
29
205
1.42
1.01
1.6
1.4
1.0
1.0
g/l
0.00
29
205
107
903
1.19
0.99
11.9
11.0
24.2
24.3
mmol/l
0.15
95
857
0
29
0.00
0.97
0.0
1.0
—
—
—
0
0
46
355
1.30
0.95
1.0
1.1
—
—
—
0
0
50
392
1.28
0.92
1.6
1.7
5879.4
1288.8
u/l
0.36
11
122
35
261
1.35
0.91
1.3
1.1
—
—
—
0
0
50
393
1.28
0.91
2.7
2.3
133.7
131.2
g/l
0.21
40
277
15
94
1.60
0.90
1.2
1.2
—
—
—
0
0
15
94
1.60
0.90
1.1
1.0
—
—
—
0
0
6
29
2.07
0.89
1.3
4.4
40.0
43.7
umol/l
—
6
22
45
350
1.29
0.89
1.5
1.7
—
—
—
0
0
134
1167
1.16
0.88
10.5
10.0
93.6
94.0
%
0.21
134
1161
41
317
1.30
0.85
1.0
1.1
1.8
3.4
u/ml
1.09
17
163
29
215
1.35
0.80
5.1
4.9
220.5
78.4
u/ml
—
8
58
18
122
1.48
0.80
1.1
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
0
25
0.00
0.79
0.0
2.5
—
0.6
—
0
25
8
48
1.67
0.78
1.0
1.1
—
—
—
0
0
309
2853
1.10
0.78
2.7
2.4
14.8
13.8
umol/l
1.59
278
2657
119
1039
1.15
0.78
1.1
1.0
—
—
—
0
0
35
269
1.31
0.77
1.8
1.7
—
—
—
0
0
23
165
1.40
0.77
1.2
1.2
0.3
0.5
u/ml
0.33
11
72
22
157
1.40
0.76
1.6
2.1
—
—
—
0
0
83
708
1.18
0.74
1.9
1.8
1.6
1.6
g/l
0.21
67
615
300
2780
1.09
0.71
1.9
1.8
1.3
1.4
%
1.46
271
2484
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
7
40
1.75
0.71
1.1
1.2
—
80.1
—
0
14
121
1069
1.14
0.69
1.4
1.4
—
—
—
0
0
21
153
1.38
0.67
1.0
1.1
—
—
—
0
0
34
268
1.27
0.65
2.7
2.5
3.8
107.8
u/ml
0.99
34
260
53
440
1.21
0.65
3.4
3.0
25.5
25.0
mmol/l
0.33
46
395
130
1160
1.13
0.65
10.7
10.0
0.7
0.7
%
0.51
130
1152
7
44
1.59
0.65
1.0
1.2
—
—
—
0
0
91
793
1.15
0.64
3.6
3.5
24.4
24.3
mmol/l
0.06
86
719
54
450
1.20
0.64
1.4
1.3
—
—
—
0
0
261
2421
1.09
0.62
3.0
2.5
25.1
23.8
%
0.77
223
2080
130
1165
1.12
0.61
10.4
9.8
1.5
1.4
%
0.22
130
1157
13
88
1.48
0.60
1.8
1.9
2.9
8.3
ug/l
—
6
59
0
20
0.00
0.60
0.0
2.0
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
0.2
—
0
10
12
80
1.50
0.59
1.8
1.6
—
—
—
0
0
13
186
0.70
0.59
1.6
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
64
547
1.17
0.59
1.3
1.4
—
—
—
0
0
297
2781
1.08
0.58
1.8
1.8
—
—
—
0
0
41
337
1.22
0.57
1.2
1.2
4.0
5.5
u/ml
0.36
17
131
30
238
1.26
0.56
1.1
1.1
—
—
—
0
0
6
38
1.58
0.54
1.3
1.6
—
—
—
0
0
25
195
1.29
0.54
2.0
1.5
35.9
35.0
%
0.03
12
117
23
178
1.29
0.53
5.7
4.3
—
—
—
0
0
10
66
1.52
0.52
1.4
1.7
—
—
—
0
0
69
601
1.15
0.52
1.5
1.2
10.8
5.9
u/ml
0.36
14
94
69
602
1.15
0.51
1.5
1.6
311.0
306.8
mu/l
0.03
60
549
278
2612
1.07
0.51
2.9
2.4
2.3
2.4
g/l
0.31
254
2436
565
5874
0.95
0.49
3.6
3.8
7.5
7.6
mg/mmol
0.02
331
3663
32
262
1.22
0.48
1.2
1.2
6.6
7.5
mmol/l
1.43
26
194
11
155
0.71
0.48
1.5
1.3
—
—
—
0
0
24
190
1.27
0.48
1.5
1.6
—
—
—
0
0
60
523
1.15
0.46
1.6
1.9
3.0
4.3
iu/l
1.28
13
194
196
1826
1.08
0.46
2.4
2.7
1.8
1.8
%
0.05
172
1648
7
50
1.40
0.45
1.0
1.1
—
—
—
0
0
64
725
0.88
0.44
2.2
1.9
—
—
—
0
0
39
330
1.18
0.44
3.9
2.8
1.4
1.5
mmol/l
0.98
39
317
22
175
1.26
0.43
1.3
1.2
—
—
—
0
0
67
593
1.13
0.43
1.5
1.2
2.2
7.5
u/ml
—
8
56
9
130
0.69
0.43
1.3
1.1
—
—
—
0
0
5
31
1.61
0.43
1.2
1.7
52.9
83.5
ng/l
—
5
31
6
94
0.64
0.42
2.5
3.4
—
—
—
0
0
122
1120
1.09
0.41
3.3
3.3
5.1
5.2
kpa
0.25
113
1053
5
33
1.52
0.41
1.0
2.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
33
277
1.19
0.41
1.6
1.6
—
—
—
0
0
163
1517
1.08
0.41
3.5
3.5
1.8
2.0
mmol/l
0.34
146
1226
15
114
1.32
0.40
1.3
1.2
—
—
—
0
0
64
568
1.13
0.40
1.3
1.2
—
—
—
0
0
5
34
1.47
0.40
1.0
1.2
—
—
—
0
0
12
88
1.37
0.40
1.0
1.1
163.9
205.2
iu/ml
0.33
12
88
217
2045
1.07
0.39
8.1
8.1
5.1
5.1
kpa
0.08
208
1965
217
2045
1.07
0.39
8.0
8.1
12.9
12.6
kpa
0.41
208
1966
41
353
1.16
0.39
1.6
1.6
—
—
—
0
0
18
142
1.27
0.38
1.7
1.8
—
—
—
0
0
44
382
1.15
0.38
1.2
1.2
325.4
286.0
u/ml
0.24
24
235
5
36
1.39
0.38
5.0
2.2
—
—
—
0
0
36
308
1.17
0.37
4.1
2.9
7.5
7.4
mmol/l
0.11
36
299
78
705
1.11
0.37
3.5
5.7
1.6
1.7
%
0.33
73
658
5
37
1.35
0.37
1.0
1.5
—
—
—
0
0
33
386
0.85
0.36
3.8
3.3
24.3
22.8
mg/l
0.10
19
231
25
207
1.21
0.36
1.2
1.2
55.1
58.5
u/l
0.23
19
143
6
42
1.43
0.35
1.0
1.3
—
—
—
0
0
22
183
1.20
0.31
1.2
1.5
—
—
—
0
0
53
475
1.12
0.31
2.0
1.8
—
—
—
0
0
26
221
1.18
0.30
3.8
2.3
21.2
25.3
mg/l
—
10
60
14
111
1.26
0.30
1.1
1.1
—
—
—
0
0
7
55
1.27
0.30
1.3
1.5
—
—
—
0
0
13
102
1.28
0.30
1.2
1.4
—
1075.0
—
0
6
18
149
1.21
0.27
2.2
1.9
3.5
3.8
mg/l
0.12
18
143
56
508
1.10
0.27
1.7
3.6
39.5
66.0
mg/l
0.91
40
409
16
194
0.82
0.27
2.2
1.8
—
—
—
0
0
16
194
0.82
0.27
2.2
1.8
—
—
—
0
0
16
194
0.82
0.27
2.2
1.8
—
—
—
0
0
8
66
1.21
0.26
1.1
1.0
—
—
—
0
0
214
2049
1.05
0.26
8.1
8.1
0.7
1.1
mmol/l
1.18
174
1626
54
492
1.10
0.25
1.7
3.6
1.3
1.7
ratio
—
5
44
62
569
1.09
0.25
3.5
4.2
3.9
3.9
mmol/l
0.13
62
539
37
330
1.12
0.25
1.3
1.5
—
—
—
0
0
9
77
1.17
0.24
1.6
1.5
—
—
—
0
0
9
77
1.17
0.24
1.6
1.5
—
—
—
0
0
51
466
1.10
0.23
2.1
1.8
—
—
—
0
0
13
106
1.23
0.23
2.1
1.7
—
—
—
0
0
7
91
0.77
0.22
3.7
2.4
—
—
—
0
0
7
91
0.77
0.22
3.7
2.4
—
—
—
0
0
7
92
0.76
0.22
3.7
2.3
—
—
—
0
0
5
40
1.25
0.22
1.2
1.1
—
—
—
0
0
5
40
1.25
0.22
1.6
1.8
20.5
18.7
umol/l
—
5
40
13
107
1.22
0.21
2.1
1.7
—
—
—
0
0
5
42
1.19
0.21
1.4
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
97.0
—
0
6
0
10
0.00
0.21
0.0
5.1
—
390.6
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
50
459
1.09
0.21
1.6
1.2
1.4
4.1
u/ml
—
5
32
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
12
145
0.83
0.21
1.7
1.3
4860.0
57985.3
e6/l
—
5
82
55
508
1.08
0.21
1.7
3.6
37.0
30.4
mg/l
0.33
40
411
12
99
1.21
0.19
1.2
1.8
—
—
—
0
0
112
1066
1.05
0.19
3.3
3.3
2.0
1.8
mmol/l
0.35
89
814
18
207
0.87
0.19
1.5
1.3
4822.9
105958.0
e6/l
—
10
144
61
653
0.93
0.19
1.8
1.7
—
—
—
0
0
18
156
1.16
0.18
2.3
1.8
—
—
—
0
0
470
4605
1.03
0.18
2.4
2.3
—
—
—
0
0
38
348
1.09
0.18
2.3
1.9
—
—
—
0
0
580
5900
0.98
0.17
2.8
3.1
7.7
7.8
mmol/l
0.16
494
5035
180
1739
1.04
0.17
8.9
8.9
124.6
122.9
g/l
0.60
174
1677
8
72
1.11
0.16
1.4
1.3
115.9
107.0
%
—
8
63
47
438
1.07
0.15
2.1
2.3
0.8
0.8
nmol/l
0.02
41
375
8
73
1.10
0.15
1.4
1.9
—
—
—
0
0
6
76
0.79
0.15
1.5
1.1
—
—
—
0
0
15
130
1.15
0.15
1.0
1.1
—
—
—
0
0
9
78
1.15
0.15
1.1
1.6
—
—
—
0
0
20
178
1.12
0.15
1.8
2.6
—
—
—
0
0
47
502
0.93
0.14
1.7
1.6
6231.2
11939.9
e6/l
0.71
32
368
32
295
1.09
0.14
5.9
3.7
0.5
1.3
%
2.94
24
244
16
142
1.13
0.12
1.7
1.2
—
—
—
0
0
12
104
1.15
0.12
2.3
2.0
20.3
97.0
ug/l
0.50
12
92
37
346
1.07
0.12
1.3
1.1
—
—
—
0
0
15
133
1.13
0.12
1.4
1.5
—
—
—
0
0
16
143
1.12
0.11
1.7
1.2
—
—
—
0
0
12
105
1.14
0.11
1.4
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
13
115
1.13
0.10
1.2
1.1
—
—
—
0
0
65
623
1.04
0.10
1.3
1.3
216.7
203.5
miu/ml
0.12
26
300
74
713
1.04
0.09
4.2
3.6
49.1
51.3
%
0.31
74
705
34
320
1.06
0.09
1.1
1.2
—
—
—
0
0
10
87
1.15
0.09
1.1
1.2
—
—
—
0
0
13
116
1.12
0.09
1.1
1.2
14.0
20.7
u/l
0.57
13
97
6
55
1.09
0.09
1.2
1.2
—
—
—
0
0
5
61
0.82
0.08
1.0
1.2
—
—
—
0
0
5
60
0.83
0.08
1.0
1.2
—
—
—
0
0
7
65
1.08
0.08
1.1
1.3
—
—
—
0
0
7
66
1.06
0.08
1.4
1.2
—
—
—
0
0
7
66
1.06
0.08
1.0
1.4
—
—
—
0
0
72
697
1.03
0.08
3.0
3.6
168.9
2182.6
u/ml
0.78
63
593
8
75
1.07
0.07
1.6
1.5
—
—
—
0
0
8
75
1.07
0.07
1.6
1.5
—
—
—
0
0
8
75
1.07
0.07
1.9
1.6
8.4
8.3
ug/l
—
8
75
43
412
1.04
0.07
1.2
1.2
—
—
—
0
0
184
1871
0.98
0.07
2.3
2.3
0.2
0.2
g/l
0.01
175
1767
19
177
1.07
0.06
5.8
3.7
57.3
55.3
%
0.20
12
127
40
384
1.04
0.06
3.7
3.6
65.9
928.9
u/ml
0.77
33
364
68
661
1.03
0.06
3.4
4.1
1.3
1.4
mmol/l
0.17
68
652
224
2212
1.01
0.06
23.1
19.9
1.3
1.2
inr
0.32
32
307
10
110
0.91
0.05
1.2
1.8
1.7
2.1
u/field
—
10
83
13
120
1.08
0.05
1.5
1.5
13.5
6.9
u/l
—
6
63
10
91
1.10
0.04
1.1
1.1
1493.0
1634.1
miu/ml
—
10
91
23
241
0.95
0.04
2.5
1.9
—
—
—
0
0
25
239
1.05
0.04
1.7
1.5
—
—
—
0
0
71
696
1.02
0.04
1.7
2.1
4.3
1.8
ug/l
0.36
62
634
13
121
1.07
0.03
2.1
1.7
—
—
—
0
0
10
108
0.93
0.03
2.9
2.2
—
—
—
0
0
10
108
0.93
0.03
2.9
2.2
—
—
—
0
0
10
108
0.93
0.03
2.9
2.2
—
—
—
0
0
10
108
0.93
0.03
2.9
2.2
—
—
—
0
0
43
420
1.02
0.02
1.5
1.4
—
—
—
0
0
98
971
1.01
0.01
1.6
1.6
—
—
—
0
0
23
237
0.97
0.01
1.8
1.5
—
—
—
0
0
71
702
1.01
0.01
3.1
3.4
24.8
25.0
mmol/l
0.25
64
654
10
106
0.94
0.01
1.3
1.4
—
—
—
0
0
103
1037
0.99
0.01
1.6
1.4
—
—
—
0
0
15
144
1.04
0.00
1.1
1.0
—
—
—
0
0
23
235
0.98
0.00
1.8
1.5
—
—
—
0
0
31
309
1.00
0.00
1.6
1.5
—
—
—
0
0
16
164
0.98
0.00
1.6
1.3
1713.7
2968.6
e6/l
—
9
112
17
166
1.02
0.00
1.2
1.4
—
—
—
0
0
23
234
0.98
0.00
1.8
1.5
—
—
—
0
0
23
234
0.98
0.00
1.8
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
56
556
1.01
0.00
5.2
2.8
0.5
0.3
u/ml
1.37
28
308
23
228
1.01
0.00
2.4
1.9
—
—
—
0
0
28
278
1.01
0.00
1.7
1.5
—
—
—
0
0
38
378
1.01
0.00
1.8
1.5
—
—
—
0
0
197
1967
1.00
0.00
3.7
4.2
65.2
20.8
ug/l
0.46
152
1578
23
233
0.99
0.00
1.8
1.5
—
—
—
0
0
9
96
0.94
0.00
1.6
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
0.00
1.2
1.2
—
—
—
0
0
8
79
1.01
0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
9
94
0.96
0.00
1.6
1.4
—
—
—
0
0
116
1160
1.00
0.00
5.6
7.3
24.9
24.6
mmol/l
0.46
109
1083
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
8
88
0.91
0.00
2.5
2.2
—
233.2
—
0
17
0
7
0.00
0.00
0.0
3.0
—
8.3
—
0
7
8
83
0.96
0.00
1.0
1.2
—
—
—
0
0
10
100
1.00
0.00
1.3
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
1.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
14.6
—
—
—
0
0
6
62
0.97
0.00
1.2
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
4.3
—
—
—
0
0
9
95
0.95
0.00
1.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
1475.5
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
2.4
—
0
7
10
100
1.00
0.00
1.3
1.3
—
—
—
0
0
10
100
1.00
0.00
1.3
1.3
—
—
—
0
0
10
100
1.00
0.00
1.3
1.3
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_PRESBYOPIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PRESBYOPIA | 1.379 [1.18, 1.61] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.285 |
During the follow-up period (1.1.1998 — 31.12.2019), 328 out of 3648 females with H7_PRESBYOPIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PRESBYOPIA | 1.398 [1.2, 1.63] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.031 |
During the follow-up period (1.1.1998 — 31.12.2019), 432 out of 2916 males with H7_PRESBYOPIA died.
Mortality risk
Mortality risk for people of age
years, who have H7_PRESBYOPIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.137% | 0.295% |
| 5 | 0.843% | 1.703% |
| 10 | 2.094% | 4.247% |
| 15 | 4.011% | 8.649% |
| 20 | 7.218% | 14.601% |
Relationships between endpoints
↥Index endpoint: H7_PRESBYOPIA – Presbyopia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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