Benign neoplasm: Conjunctiva

CD2_BENIGN_CONJUNCTIVA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D31.0&
  • Hospital discharge: ICD-9 2243
  • Hospital discharge: ICD-8 22400
  • Cause of death: ICD-10 D31.0&
  • Cause of death: ICD-9 2243
  • Cause of death: ICD-8 22400

2 out of 7 registries used, show all original rules.

1168

4. Check minimum number of events

None

1168

5. Include endpoints

None

1168

6. Filter based on genotype QC (FinnGen only)

1168

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D31
Name in latin
Neoplasma benignum conjunctivae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9125 4799 4289
Only index persons 8425 4519 3906
Unadjusted period prevalence (%)
Whole population 0.13 0.14 0.12
Only index persons 0.16 0.17 0.15
Median age at first event (years)
Whole population 46.75 47.84 45.62
Only index persons 46.86 48.15 45.37

-FinnGen-

Key figures

All Female Male
Number of individuals 1168 687 481
Unadjusted period prevalence (%) 0.23 0.23 0.21
Median age at first event (years) 53.42 50.89 57.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1037
Matched controls
10369
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
4503599627370496.0
323.0
907
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
990.1
309.1
288
*
CFA20
NOMESCO Finland
Biopsy of conjunctiva
344.2
122.0
121
*
22400
ICD-8 Finland
Benign neoplasm of eye, Conjunctivae
+∞
97.4
92
*
XCK10
NOMESCO Finland
Photography of fundus of eye
5.0
61.5
219
523
CBB30
NOMESCO Finland
Excision of lesion of eyelid
10.9
57.6
114
116
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
9.1
51.8
113
137
CF2S4
NOMESCO Finland
Photography of conjunctiva
98.4
43.1
47
5
2243A
ICD-9 Finland
Benign neoplasm of eye, Conjunctiva
+∞
40.9
39
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.3
34.0
491
2936
CBA10
NOMESCO Finland
Biopsy of eyelid
15.4
30.3
50
34
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.2
29.4
408
2346
3401
FHL
Removal of local modification or taking a specimen in the operating room
+∞
28.2
27
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.5
23.8
216
991
H00.1
ICD-10 Finland
Chalazion
5.2
22.9
73
149
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
20.6
21.8
32
16
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
17.1
19.2
30
18
H04.10
ICD-10 Finland
Dry eye syndrome
2.7
17.8
133
543
C69.00
ICD-10 Finland
Malignant tumor of the conjunctiva without histology
86.4
15.6
17
*
ZXA00
NOMESCO Finland
Right side
1.9
15.3
297
1845
F29
ICPC
Eye symptom/complaint other
2.6
14.0
104
421
CBB00
NOMESCO Finland
Excision of chalazion
6.9
12.7
31
46
S01GX01
ATC
cromoglicic acid; ophthalmic
1.9
11.7
206
1224
WX002
NOMESCO Finland
Sedation and analgesia
1.8
11.4
211
1274
CD2S4
NOMESCO Finland
Photography of eye
12.0
11.4
20
17
H11.8
ICD-10 Finland
Other specified disorders of conjunctiva
20.3
11.1
16
8
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
43.8
10.9
13
*
H01.0
ICD-10 Finland
Blepharitis
2.7
10.8
72
276
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.1
10.7
122
612
CAB00
NOMESCO Finland
Anterior orbitotomy with excision of lesion
111.1
10.4
11
*
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.7
10.4
72
280
S18
ICPC
Laceration/cut
1.6
10.1
402
2989
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.6
10.0
74
301
H11.9
ICD-10 Finland
Disorder of conjunctiva, unspecified
40.5
10.0
12
*
ZXA05
NOMESCO Finland
Left side
1.6
9.2
258
1753
WX110
NOMESCO Finland
Local anesthesy
1.5
9.1
670
5674
N17
ICPC
Vertigo/dizziness
2.0
9.0
117
618
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
10.8
8.8
16
15
A98
ICPC
Health maint/preventive medicine
2.2
8.8
982
9241
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
4.6
8.7
29
65
R03AC02
ATC
salbutamol; inhalant
1.5
8.6
506
4061
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.1
8.1
24
48
H02AB06
ATC
prednisolone; systemic
1.5
7.6
436
3451
CBB99
NOMESCO Finland
Other excision or destruction of lesion of eyelid
10.1
7.5
14
14
H11.0
ICD-10 Finland
Pterygium
7.2
7.5
17
24
CFD10
NOMESCO Finland
Repair of conjunctiva
80.6
7.4
8
*
D31.1
ICD-10 Finland
Benign neoplasm: Cornea
80.6
7.4
8
*
S21
ICPC
Skin texture symptom/complaint
1.8
7.3
119
681
H10.4
ICD-10 Finland
Chronic conjunctivitis
5.8
7.2
19
33
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.0
6.9
90
477
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
13.9
6.9
11
8
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
8.3
6.8
14
17
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
4.2
6.8
24
58
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
40.3
6.8
8
*
T15.1
ICD-10 Finland
Foreign body in conjunctival sac
4.7
6.7
21
45
H02.8
ICD-10 Finland
Other specified disorders of eyelid
12.3
6.6
11
9
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
6.6
254
1842
A02BC02
ATC
pantoprazole; systemic
1.4
6.5
610
5234
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.5
374
2941
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
6.5
391
3098
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.4
264
1937
XCX10
NOMESCO Finland
Other photography of eye
70.3
6.4
7
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
6.3
196
1352
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.2
319
2449
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
6.2
217
1536
ZXA10
NOMESCO Finland
Bilateral
1.6
6.2
170
1137
S82
ICPC
Naevus/mole
1.7
6.2
116
700
H33.0
ICD-10 Finland
Retinal detachment with retinal break
3.2
6.1
30
97

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
535
3889
1.69
16.89
2.3
2.1
—
—
—
0
0
610
4973
1.47
9.56
7.2
5.9
0.2
0.2
e9/l
0.07
536
4386
429
3288
1.48
9.06
3.3
3.4
2.4
2.4
mmol/l
0.50
369
2880
666
5565
1.46
8.93
10.1
8.9
3.9
4.1
e9/l
1.06
585
4884
589
4811
1.45
8.89
6.8
5.6
0.0
0.0
e9/l
0.30
516
4178
584
4791
1.44
8.44
6.8
5.6
0.6
0.6
e9/l
0.45
509
4151
841
7423
1.47
7.96
8.4
7.5
76.0
78.4
u/l
1.11
793
6962
973
8861
1.59
7.88
5.3
4.7
1.8
2.0
mu/l
0.78
893
8089
533
4370
1.40
7.38
6.9
5.8
0.7
0.7
%
0.36
501
4078
547
4509
1.40
7.31
6.9
5.8
2.8
2.8
%
0.00
513
4197
589
4926
1.39
7.18
6.9
5.7
1.9
1.9
e9/l
0.00
520
4359
548
4530
1.40
7.15
7.1
6.0
8.7
8.6
%
0.33
514
4243
502
4120
1.38
6.70
5.2
4.7
35.9
35.5
g/l
0.85
462
3822
425
3398
1.39
6.62
4.5
3.7
55.8
90.8
e6/l
1.13
299
2424
548
4573
1.37
6.55
6.6
5.7
57.3
57.4
%
0.03
511
4284
594
5034
1.37
6.39
6.0
6.2
11.9
11.2
umol/l
0.48
557
4771
1119
10690
2.11
6.38
25.0
20.9
6.7
6.7
e9/l
0.01
1089
10396
1065
10022
1.71
6.35
14.8
13.5
—
—
—
0
0
1054
9896
1.67
6.29
19.2
16.5
4.0
4.0
mmol/l
0.43
1025
9621
1118
10687
2.08
6.20
24.9
20.8
91.1
91.0
fl
0.09
1100
10535
1118
10688
2.08
6.18
24.8
20.8
30.3
30.3
pg
0.39
1100
10534
553
4650
1.36
6.17
7.0
5.9
27.8
27.7
%
0.02
515
4336
1118
10689
2.07
6.16
24.9
20.9
4.5
4.5
e12/l
0.32
1086
10400
332
2571
1.41
6.15
4.1
3.1
—
—
—
0
0
1118
10693
2.06
6.09
25.1
21.0
135.0
135.1
g/l
0.03
1099
10534
980
9066
1.50
6.07
4.1
3.9
1.3
1.3
mmol/l
0.43
880
8288
475
3909
1.36
6.05
2.2
2.0
96.6
94.9
pmol/l
0.34
239
2006
1117
10684
2.04
6.02
25.0
20.9
249.5
250.6
e9/l
0.22
1089
10420
338
2639
1.40
5.94
4.1
3.1
0.3
0.5
e6/l
0.85
251
2006
1028
9619
1.57
5.92
5.3
4.9
2.7
2.7
mmol/l
0.42
946
8848
797
7119
1.38
5.91
4.9
4.1
11.0
12.3
mm/h
2.14
738
6562
241
1774
1.45
5.88
3.1
3.0
2.5
2.4
mmol/l
0.30
216
1559
1013
9452
1.54
5.86
4.7
4.4
4.6
4.7
mmol/l
0.48
924
8755
1049
9869
1.62
5.81
19.1
16.4
139.7
139.7
mmol/l
0.00
1023
9611
823
7406
1.38
5.71
4.3
4.0
14.8
14.8
pmol/l
0.36
743
6733
749
6643
1.36
5.69
5.2
4.4
—
—
—
0
0
187
1318
1.50
5.67
1.3
1.2
—
—
—
0
0
400
3235
1.36
5.59
6.7
5.6
—
—
—
0
0
362
2892
1.36
5.45
4.1
3.2
17.5
88.6
e6/l
2.46
281
2251
1005
9393
1.50
5.43
4.6
4.3
1.5
1.5
mmol/l
0.23
915
8644
1025
9622
1.53
5.39
17.1
14.2
22.0
23.8
mg/l
1.08
813
7643
358
2861
1.36
5.36
4.8
4.1
7.4
7.4
ph
0.11
64
556
559
4775
1.33
5.34
7.2
6.8
1.2
1.2
mmol/l
0.70
473
4022
722
6400
1.34
5.32
5.5
4.5
42.3
2876.7
e6/l
2.07
15
97
516
4364
1.33
5.26
6.5
6.0
1.2
1.2
mmol/l
0.08
463
3946
1074
10203
1.65
5.22
12.2
10.4
25.5
25.8
u/l
0.25
1041
9853
464
3903
1.31
4.78
11.2
9.5
1.3
1.2
inr
0.88
130
1143
247
1891
1.39
4.76
1.6
1.5
2.4
2.4
g/l
0.01
136
1160
264
2046
1.38
4.72
3.5
2.6
3.6
6.1
e6/l
4.23
234
1804
496
4226
1.30
4.60
3.3
2.7
122.6
122.3
ug/l
0.01
460
3896
435
3659
1.30
4.39
3.9
3.7
42.9
51.4
ng/l
0.19
288
2538
990
9314
1.41
4.32
4.9
4.5
5.9
5.9
mmol/l
0.20
902
8465
161
1166
1.44
4.23
2.1
2.2
222.2
128.2
ug/g
0.89
123
912
293
2343
1.33
4.23
2.3
2.3
—
—
—
0
0
340
2791
1.31
4.06
2.8
3.0
1323.5
1335.7
ng/l
0.02
292
2383
128
899
1.48
3.95
1.5
1.5
—
—
—
0
0
157
1147
1.43
3.94
1.8
1.6
—
—
—
0
0
170
1264
1.40
3.86
1.4
1.3
—
—
—
0
0
16
55
2.94
3.74
3.2
2.3
24.0
15.0
%
—
10
25
281
2283
1.30
3.56
1.6
1.5
20.5
20.7
nmol/l
0.10
238
1948
740
6756
1.26
3.52
4.3
3.8
—
—
—
0
0
267
2159
1.31
3.50
1.7
1.7
0.9
1.1
mg/l
2.27
189
1649
366
3083
1.27
3.49
2.4
2.3
—
—
—
0
0
108
753
1.48
3.48
1.2
1.2
—
—
—
0
0
303
2498
1.29
3.43
2.8
2.7
7768.0
6696.3
umol/l
0.13
271
2165
144
1063
1.40
3.42
1.2
1.3
—
—
—
0
0
264
2145
1.30
3.33
4.9
4.5
—
—
—
0
0
224
1782
1.32
3.30
2.0
1.7
1298.2
1190.6
nmol/l
0.50
165
1332
297
2454
1.28
3.29
2.4
2.1
3.0
3.0
mg/l
0.12
247
2089
360
3052
1.26
3.21
2.8
2.5
60.7
56.4
u/l
0.29
332
2837
92
633
1.49
3.18
2.3
2.5
12.0
16.2
au/ml
—
6
27
265
2167
1.29
3.17
4.3
3.7
—
—
—
0
0
146
1099
1.38
3.10
3.1
2.7
6.7
8.2
umol/l
0.69
128
956
624
5635
1.23
3.09
5.1
4.9
6.6
6.7
mmol/l
0.65
581
5258
167
1285
1.35
3.08
1.4
1.3
489.7
502.2
titre
0.04
37
278
287
2385
1.27
3.01
7.4
6.6
—
—
—
0
0
9
21
4.31
2.99
4.7
2.0
107.8
176.3
e6/l
—
9
8
262
2160
1.27
2.93
1.3
1.3
1.9
1.6
u/ml
0.10
63
576
236
1928
1.28
2.83
3.6
2.8
548.8
548.9
mosm/kgh2o
0.00
201
1658
534
4788
1.21
2.71
4.6
3.7
0.0
0.0
estimate
0.80
99
884
928
8799
1.27
2.70
6.3
5.7
39.3
39.9
mmol/mol
1.28
862
8148
857
8056
1.24
2.68
21.4
17.2
13.7
13.7
%
0.30
848
7882
340
2915
1.23
2.68
2.1
2.1
194.1
233.6
u/l
0.33
315
2749
478
4247
1.21
2.64
11.3
9.5
0.0
0.0
e9/l
0.82
387
3486
117
873
1.38
2.64
2.4
2.5
161.1
42.0
u/l
0.46
95
744
525
4711
1.21
2.61
4.6
3.7
0.0
0.0
estimate
0.00
100
912
92
663
1.42
2.55
1.5
1.4
—
—
—
0
0
22
108
2.06
2.52
1.7
1.7
—
—
—
0
0
186
1496
1.29
2.52
3.4
2.9
2.8
2.4
e6/l
0.21
97
820
88
632
1.42
2.49
2.3
2.2
12.2
12.9
nmol/l
0.34
76
560
202
1647
1.27
2.46
1.3
1.3
31.7
33.3
iu/ml
0.06
60
533
160
1268
1.30
2.43
2.9
2.4
22.8
22.8
%
0.01
133
1079
18
83
2.19
2.41
1.4
1.5
—
—
—
0
0
83
595
1.43
2.38
2.4
3.3
4.3
4.6
pmol/l
1.86
75
519
206
1697
1.26
2.30
3.3
3.0
0.9
0.8
ug/l
0.17
142
1114
41
254
1.64
2.30
1.4
1.8
3.0
5.1
iu/l
1.01
14
83
26
141
1.86
2.29
2.4
1.7
0.5
0.8
g/l
1.49
21
108
523
4732
1.19
2.28
5.8
5.0
0.0
0.0
estimate
0.50
103
919
168
1356
1.28
2.22
2.7
2.4
2.4
2.3
g/l
0.26
161
1259
84
612
1.40
2.21
1.5
1.2
281.6
205.7
u/ml
0.37
78
556
301
2596
1.21
2.19
1.8
1.7
1.4
1.4
mmol/l
0.10
259
2185
181
1477
1.27
2.19
2.7
2.4
13.1
13.1
umol/l
0.04
169
1371
82
597
1.40
2.17
1.9
1.8
1.1
1.5
g/l
1.63
75
546
10
37
2.72
2.10
3.1
2.5
—
—
—
0
0
35
214
1.66
2.08
2.3
2.2
129.8
129.0
g/l
0.07
25
164
302
2618
1.21
2.08
4.8
4.2
—
—
—
0
0
5
10
5.02
2.07
1.0
1.4
—
—
—
0
0
131
1038
1.30
2.01
1.8
1.5
—
—
—
0
0
24
133
1.82
2.00
1.9
2.8
—
—
—
0
0
329
2897
1.19
1.90
5.5
4.9
5.2
2.9
ug/l
0.47
297
2588
185
1540
1.24
1.90
3.0
3.4
0.8
0.8
mmol/l
0.34
171
1437
109
850
1.31
1.89
1.4
1.4
—
—
—
0
0
853
8116
1.19
1.88
22.7
18.3
332.2
332.4
g/l
0.30
847
8062
81
606
1.36
1.86
1.3
1.2
—
—
—
0
0
293
2561
1.19
1.83
5.8
4.1
0.0
0.0
estimate
1.08
103
892
917
8789
1.20
1.83
19.5
15.2
39.5
39.8
%
0.34
691
6265
129
1035
1.28
1.82
2.1
2.6
1.7
1.8
%
0.38
112
921
28
169
1.67
1.78
1.2
1.2
—
—
—
0
0
99
770
1.31
1.77
8.9
8.7
—
—
—
0
0
69
508
1.38
1.76
1.6
1.3
—
—
—
0
0
238
2051
1.20
1.74
1.7
1.7
50000431.2
24926593.9
pmol/l
0.21
202
1693
135
1097
1.26
1.72
7.1
8.1
0.7
1.3
mmol/l
1.05
109
864
135
1099
1.26
1.70
7.0
8.1
5.1
5.1
kpa
0.01
127
1055
10
42
2.39
1.68
1.6
3.1
338.6
1427.0
u/ml
—
10
42
12
55
2.19
1.67
3.7
2.1
0.4
0.2
e9/l
1.20
12
49
30
188
1.61
1.67
1.4
1.5
—
—
—
0
0
334
2976
1.17
1.65
3.8
3.1
—
—
—
0
0
134
1099
1.25
1.59
7.0
8.1
12.4
12.2
kpa
0.25
127
1056
69
518
1.35
1.58
9.5
11.2
—
—
—
0
0
44
306
1.46
1.56
1.2
1.2
—
—
—
0
0
12
57
2.12
1.55
3.9
2.1
442.3
535.4
e6/l
0.40
12
49
147
1223
1.23
1.54
30.5
25.5
1.6
1.3
inr
0.97
14
159
49
349
1.42
1.54
1.9
2.1
23.3
21.5
s
0.42
42
310
55
400
1.39
1.54
2.1
1.8
—
—
—
0
0
130
1068
1.24
1.53
1.8
1.7
—
—
—
0
0
194
1662
1.20
1.51
2.1
1.8
—
—
—
0
0
11
51
2.17
1.51
1.1
1.0
—
—
—
0
0
6
21
2.87
1.50
1.0
1.1
—
—
—
0
0
14
72
1.96
1.49
1.1
1.1
—
—
—
0
0
98
783
1.27
1.46
2.7
3.0
204.3
210.5
ng/l
0.04
90
715
7
28
2.51
1.45
1.1
1.6
—
—
—
0
0
164
1389
1.21
1.45
1.8
1.6
—
—
—
0
0
313
2803
1.16
1.44
3.5
3.3
232.0
330.5
mg/l
0.21
202
1790
13
66
1.98
1.43
1.3
1.9
—
44.2
—
0
9
6
22
2.74
1.43
1.2
1.0
—
—
—
0
0
16
88
1.83
1.42
1.4
1.1
—
—
—
0
0
334
3009
1.15
1.41
3.5
3.1
7.1
7.6
mmol/l
0.96
278
2523
120
987
1.24
1.41
7.6
8.5
95.8
95.6
%
0.08
115
953
15
81
1.86
1.40
1.4
1.2
2.5
0.9
u/ml
—
8
34
31
207
1.51
1.36
2.6
3.9
—
—
—
0
0
35
240
1.47
1.36
1.1
1.1
—
—
—
0
0
24
151
1.60
1.35
1.0
1.1
—
—
—
0
0
40
283
1.43
1.33
4.2
3.1
—
—
—
0
0
93
750
1.26
1.31
3.1
2.8
9.9
10.7
g/l
1.19
86
685
30
201
1.51
1.30
5.0
3.6
56.0
58.0
%
0.42
30
201
6
24
2.51
1.30
1.3
1.1
—
—
—
0
0
16
91
1.77
1.29
1.1
1.2
—
—
—
0
0
28
186
1.52
1.27
3.0
2.7
—
—
—
0
0
14
77
1.83
1.25
1.2
1.1
—
—
—
0
0
29
195
1.50
1.25
4.7
3.3
4.3
4.4
e9/l
0.04
29
195
6
25
2.41
1.24
1.3
2.5
—
—
—
0
0
79
629
1.27
1.24
2.9
3.8
7.4
7.4
ph
0.43
12
81
17
100
1.71
1.24
1.1
1.6
—
—
—
0
0
17
100
1.71
1.24
1.1
1.1
—
—
—
0
0
94
765
1.25
1.23
1.9
3.2
65.3
66.8
g/l
1.62
87
701
110
911
1.23
1.23
2.5
2.3
0.2
0.2
g/l
0.67
105
856
40
288
1.40
1.22
1.5
1.5
299.1
281.6
ug/g
0.23
28
166
181
1574
1.18
1.21
1.4
1.3
15.4
13.3
u/ml
0.13
68
610
22
140
1.58
1.20
1.1
1.2
4.1
5.9
u/ml
—
8
58
119
997
1.22
1.20
4.3
4.3
3.5
22.9
ug/l
1.61
98
822
17
101
1.69
1.20
1.4
1.3
—
—
—
0
0
26
173
1.51
1.18
1.2
1.6
—
—
—
0
0
23
149
1.55
1.17
1.0
1.1
—
—
—
0
0
94
770
1.24
1.17
2.0
2.6
70.5
71.4
e9/l
0.10
60
594
10
50
2.01
1.16
1.1
1.2
—
—
—
0
0
135
1149
1.20
1.16
1.5
1.4
—
—
—
0
0
21
134
1.58
1.15
1.0
1.1
0.5
3.3
u/ml
—
6
32
55
423
1.32
1.13
1.2
1.2
—
—
—
0
0
13
73
1.79
1.11
1.8
1.3
0.9
1.0
g/l
1.33
13
73
21
136
1.55
1.09
1.0
1.1
0.7
1.9
u/ml
—
9
56
26
177
1.48
1.08
1.1
1.2
279.6
269.8
u/ml
0.07
20
106
305
2786
1.13
1.04
3.8
3.9
—
—
—
0
0
9
46
1.96
1.03
1.1
1.2
—
—
—
0
0
91
755
1.22
1.03
4.0
3.8
84.4
83.5
ng/l
0.04
75
665
49
377
1.31
1.03
1.4
1.4
28.7
29.6
iu/l
0.06
39
326
23
155
1.49
1.01
1.3
1.4
—
—
—
0
0
16
99
1.62
1.00
2.1
2.4
—
—
—
0
0
98
824
1.21
0.98
2.3
2.4
6.0
7.2
ug/l
0.42
82
724
9
49
1.84
0.98
2.3
1.6
1.3
1.3
nmol/l
—
9
36
10
54
1.86
0.96
1.3
1.0
—
—
—
0
0
48
373
1.30
0.95
2.4
2.7
—
—
—
0
0
21
141
1.50
0.95
1.0
1.1
0.9
6.0
u/ml
2.45
11
69
7
37
1.90
0.94
1.7
1.5
—
—
—
0
0
33
243
1.37
0.93
1.3
1.4
10.3
10.5
u/l
0.02
24
198
6
27
2.23
0.93
1.7
2.1
—
—
—
0
0
24
167
1.45
0.92
1.5
1.2
—
—
—
0
0
6
28
2.15
0.91
1.0
1.1
—
—
—
0
0
488
4607
1.10
0.90
4.4
4.0
—
—
—
0
0
20
135
1.49
0.89
1.7
1.5
0.9
0.3
nmol/l
0.68
11
103
6
29
2.07
0.89
1.0
1.0
—
—
—
0
0
23
160
1.45
0.89
1.1
1.1
2.4
0.9
u/ml
—
10
63
105
899
1.18
0.88
2.5
2.1
359.0
373.6
nmol/l
0.30
95
830
142
1247
1.16
0.88
6.5
5.6
1.1
1.0
mmol/l
0.35
135
1150
10
56
1.79
0.88
1.1
1.2
—
—
—
0
0
37
281
1.33
0.87
1.3
1.3
251.6
254.7
miu/ml
0.01
16
135
13
80
1.63
0.84
2.5
1.7
8.7
11.1
%
1.47
13
80
6
32
1.88
0.82
1.2
1.0
—
—
—
0
0
318
2956
1.10
0.79
4.5
4.0
7.7
9.1
mg/mmol
0.31
207
1867
6
33
1.82
0.79
1.8
1.2
—
—
—
0
0
5
100
0.50
0.77
1.0
1.1
—
—
—
0
0
17
115
1.49
0.77
1.9
1.4
57.9
43.3
mu/l
0.18
17
106
90
772
1.18
0.76
4.7
4.1
0.0
0.1
%
0.84
21
211
0
28
0.00
0.76
0.0
2.3
—
—
—
0
0
158
1415
1.13
0.76
2.0
2.0
—
—
—
0
0
27
201
1.35
0.75
2.8
2.5
16.4
16.0
%
0.14
17
106
5
24
2.09
0.74
1.2
1.0
—
—
—
0
0
15
219
0.68
0.73
4.3
3.3
1.4
1.6
mmol/l
0.35
15
214
31
237
1.32
0.73
3.1
2.9
7.9
8.1
kpa
0.26
31
217
76
646
1.19
0.72
1.9
2.8
—
—
—
0
0
87
749
1.17
0.72
4.6
3.9
0.2
0.6
%
2.17
18
173
17
117
1.46
0.72
1.0
1.0
2.2
3.5
u/ml
—
6
42
16
109
1.47
0.71
1.0
1.0
2.6
5.1
u/ml
—
8
36
5
26
1.93
0.70
2.0
1.7
—
—
—
0
0
36
283
1.28
0.70
1.4
1.2
—
—
—
0
0
7
41
1.71
0.70
1.0
1.1
1036.0
1862.0
miu/ml
—
7
41
14
93
1.51
0.69
1.1
1.5
—
—
—
0
0
227
2090
1.11
0.69
5.0
4.1
1.0
1.0
kg/l
0.38
28
306
5
27
1.86
0.68
7.8
4.8
—
—
—
0
0
7
42
1.67
0.68
2.0
2.0
9.8
220.0
ug/l
—
7
35
85
738
1.16
0.65
5.0
4.2
0.3
0.6
%
0.20
20
182
22
163
1.36
0.64
1.5
1.4
—
—
—
0
0
22
163
1.36
0.64
1.6
1.4
—
—
—
0
0
13
87
1.50
0.63
3.3
1.3
—
—
—
0
0
95
834
1.15
0.63
6.5
7.2
8.7
9.8
mmol/l
1.02
90
791
6
105
0.57
0.62
2.2
2.3
—
—
—
0
0
25
323
0.77
0.61
2.4
1.7
—
—
—
0
0
41
335
1.23
0.60
1.8
1.6
—
—
—
0
0
57
482
1.19
0.60
2.2
2.4
—
—
—
0
0
280
2625
1.09
0.59
4.2
3.4
—
—
—
0
0
27
210
1.29
0.59
2.4
4.5
2.5
2.8
mmol/l
0.23
21
143
16
114
1.41
0.59
2.0
1.4
289.9
280.0
mosm/kgh2o
—
10
85
19
253
0.75
0.58
3.7
4.7
—
—
—
0
0
15
106
1.42
0.57
1.1
1.6
—
—
—
0
0
28
353
0.79
0.57
2.3
1.7
—
—
—
0
0
8
54
1.48
0.57
1.3
1.8
—
—
—
0
0
197
1822
1.10
0.56
3.5
3.8
751.4
350.5
ng/l
0.45
150
1406
28
351
0.79
0.55
2.3
1.7
—
—
—
0
0
55
469
1.18
0.54
3.0
3.9
—
—
—
0
0
28
350
0.80
0.54
2.3
1.7
—
—
—
0
0
76
666
1.15
0.54
1.3
1.2
221.9
138.7
iu/ml
0.64
30
261
17
125
1.37
0.53
1.0
1.3
—
0.6
nmol/l
—
0
7
31
382
0.81
0.53
1.7
1.9
2.1
2.3
ug/l
0.04
26
336
28
349
0.80
0.53
2.0
1.6
—
—
—
0
0
22
170
1.30
0.51
1.7
1.5
—
—
—
0
0
9
65
1.39
0.50
3.9
2.1
—
—
—
0
0
29
234
1.25
0.50
1.8
1.7
7280.1
14073.3
e6/l
1.17
24
178
77
681
1.14
0.49
1.7
1.4
—
—
—
0
0
11
76
1.45
0.48
1.0
1.0
327.6
280.2
mg/l
0.89
11
66
40
336
1.20
0.48
3.4
3.5
0.8
0.3
g/l
0.80
17
145
89
797
1.13
0.47
4.6
3.7
1.2
1.2
mmol/l
0.45
83
693
324
3401
0.93
0.47
2.8
2.8
—
—
—
0
0
22
173
1.28
0.46
1.1
1.2
—
—
—
0
0
91
819
1.12
0.45
4.8
4.0
0.6
0.9
%
0.77
21
234
15
112
1.34
0.44
1.1
1.3
—
—
nmol/l
—
0
0
16
121
1.33
0.44
1.2
1.6
46.5
58.3
%
0.63
11
85
11
152
0.72
0.44
1.5
1.1
—
—
—
0
0
34
284
1.20
0.44
3.0
4.2
2.4
1.8
ratio
—
7
27
18
230
0.78
0.44
3.0
2.5
—
—
—
0
0
24
193
1.25
0.43
1.1
1.4
—
—
—
0
0
11
151
0.73
0.43
1.5
1.1
—
—
—
0
0
12
87
1.38
0.42
2.2
2.3
—
—
—
0
0
13
96
1.36
0.41
1.5
2.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
78
866
0.89
0.41
1.4
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
45.6
—
0
5
11
79
1.40
0.40
1.5
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
1.8
—
0
17
0
18
0.00
0.40
0.0
2.3
—
55.4
—
0
9
13
97
1.34
0.39
5.5
3.3
—
—
—
0
0
72
646
1.12
0.39
2.3
2.9
5.1
4.1
e9/l
1.43
52
508
95
867
1.10
0.39
1.8
1.6
—
—
—
0
0
17
133
1.28
0.38
1.3
1.2
—
—
—
0
0
11
80
1.38
0.38
1.0
1.1
—
1.5
—
0
14
21
258
0.81
0.38
1.0
1.1
—
—
—
0
0
9
66
1.37
0.38
1.0
1.1
—
—
—
0
0
9
66
1.37
0.38
1.1
1.6
11.9
13.2
umol/l
—
9
61
9
66
1.37
0.38
5.4
3.3
—
—
—
0
0
5
36
1.39
0.38
1.0
1.1
—
—
—
0
0
20
161
1.25
0.37
4.0
1.4
—
—
—
0
0
26
217
1.20
0.35
1.2
1.8
—
—
—
0
0
10
73
1.37
0.34
1.4
1.1
—
—
—
0
0
6
44
1.37
0.34
1.0
1.4
—
—
—
0
0
27
318
0.85
0.33
1.9
2.1
17421.3
3468.2
u/l
—
7
136
17
136
1.25
0.33
1.1
1.2
—
—
—
0
0
15
118
1.27
0.33
1.0
1.3
—
—
—
0
0
15
118
1.27
0.33
1.1
1.2
—
—
—
0
0
104
964
1.09
0.32
4.0
4.2
—
—
—
0
0
258
2690
0.95
0.31
1.4
1.4
—
—
—
0
0
26
221
1.18
0.30
1.1
1.5
136.4
664.7
e6/l
0.55
20
181
26
221
1.18
0.30
1.1
1.4
1.9
9.2
e6/l
1.48
19
176
7
54
1.30
0.30
1.9
1.6
—
10.8
—
0
5
33
377
0.87
0.29
5.8
4.3
—
—
—
0
0
7
57
1.23
0.29
2.7
3.2
—
—
—
0
0
23
268
0.86
0.27
2.5
1.8
—
—
—
0
0
10
128
0.78
0.27
3.4
2.8
4.0
4.0
mmol/l
—
10
128
10
128
0.78
0.27
3.4
2.8
106.0
105.4
mmol/l
—
10
128
14
113
1.24
0.26
1.5
1.6
—
—
—
0
0
14
113
1.24
0.26
1.5
1.6
—
—
—
0
0
14
113
1.24
0.26
1.5
1.6
—
—
—
0
0
14
113
1.24
0.26
1.5
1.6
—
—
—
0
0
67
616
1.09
0.26
3.1
2.9
—
—
—
0
0
24
206
1.17
0.26
3.1
2.7
—
—
—
0
0
5
71
0.70
0.26
1.0
1.5
—
69.3
—
0
7
5
72
0.69
0.26
1.0
1.1
200.4
237.6
mg/l
—
5
64
14
115
1.22
0.23
1.6
1.3
—
—
—
0
0
70
650
1.08
0.23
4.4
5.4
—
—
—
0
0
28
247
1.14
0.22
3.1
2.4
147.1
96.6
ug/min
0.23
20
150
13
157
0.83
0.22
2.5
1.6
—
—
—
0
0
43
472
0.91
0.22
2.7
3.6
—
—
—
0
0
17
144
1.18
0.22
3.5
5.3
372.8
366.0
umol/l
0.05
12
128
10
124
0.80
0.21
3.4
2.8
—
—
—
0
0
5
42
1.19
0.21
1.8
2.4
49.4
47.9
umol/l
—
5
31
0
11
0.00
0.21
0.0
4.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
0.4
—
0
5
0
11
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
17.6
—
0
10
0
12
0.00
0.21
0.0
1.0
—
10.8
—
0
5
8
103
0.78
0.21
1.1
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
21
183
1.15
0.20
4.1
3.6
14.0
32.6
u/ml
2.11
21
178
19
165
1.15
0.19
3.4
3.0
—
—
—
0
0
13
110
1.18
0.17
3.5
3.5
—
—
—
0
0
45
485
0.92
0.17
1.7
1.6
—
—
—
0
0
89
846
1.06
0.17
7.2
3.9
—
—
—
0
0
23
205
1.12
0.17
2.1
2.0
—
—
—
0
0
21
236
0.89
0.17
1.3
1.3
—
—
—
0
0
20
225
0.89
0.16
4.0
4.4
—
—
—
0
0
7
88
0.79
0.14
1.0
1.2
—
—
—
0
0
9
107
0.84
0.13
1.8
1.1
—
—
—
0
0
16
142
1.13
0.12
2.2
2.7
—
—
—
0
0
10
85
1.18
0.12
1.0
1.2
—
—
—
0
0
10
85
1.18
0.12
1.2
2.0
—
1.4
—
0
6
5
45
1.11
0.10
2.8
1.5
—
—
—
0
0
5
47
1.06
0.09
1.4
3.3
—
—
—
0
0
5
47
1.06
0.09
1.0
1.2
176.6
519.8
u/l
—
5
41
80
774
1.04
0.09
4.6
3.5
—
—
—
0
0
6
54
1.11
0.09
3.5
1.7
—
51.3
—
0
5
6
58
1.03
0.08
1.3
1.7
2.0
6.0
u/field
—
6
41
5
61
0.82
0.08
1.2
1.1
—
—
—
0
0
56
539
1.04
0.08
1.4
1.4
—
—
—
0
0
17
156
1.09
0.08
1.9
1.5
—
—
—
0
0
15
164
0.91
0.08
1.6
1.7
—
—
—
0
0
8
92
0.87
0.06
1.3
1.4
—
—
—
0
0
11
99
1.11
0.06
2.3
1.5
—
—
—
0
0
36
346
1.04
0.05
1.0
1.1
—
—
—
0
0
14
151
0.93
0.05
3.1
2.2
—
—
—
0
0
40
386
1.04
0.05
1.0
1.1
—
—
—
0
0
12
110
1.09
0.05
2.8
2.6
—
—
—
0
0
20
210
0.95
0.03
5.1
3.7
31.5
26.8
mg/l
0.24
12
131
87
877
0.99
0.01
4.4
3.6
1.7
2.0
mmol/l
0.39
76
700
30
304
0.99
0.00
14.3
11.0
—
—
—
0
0
19
189
1.01
0.00
1.7
1.2
—
—
—
0
0
87
871
1.00
0.00
1.4
1.4
—
—
—
0
0
13
127
1.02
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
10.6
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
5.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
34.3
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
2.9
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
0.00
1.3
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
5.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.1
—
0
5
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
62
620
1.00
0.00
7.5
7.6
25.0
24.6
mmol/l
0.49
57
579
5
50
1.00
0.00
2.6
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
60
1.00
0.00
2.3
3.1
—
—
—
0
0
9
95
0.95
0.00
1.2
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
0.00
1.9
1.7
8.8
6.7
mmol/l
—
7
54
5
59
0.85
0.00
1.2
1.9
—
—
—
0
0
5
57
0.88
0.00
1.0
1.4
6.1
6.4
ug/l
—
5
45
0
7
0.00
0.00
0.0
2.0
—
181.3
—
0
7
0
8
0.00
0.00
0.0
1.1
—
85.5
—
0
8
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.2
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
0.00
4.8
7.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_CONJUNCTIVA and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_CONJUNCTIVA 0.859 [0.75, 0.98] 0.028
Birth year 0.999 [0.99, 1.01] 0.882

During the follow-up period (1.1.1998 — 31.12.2019), 382 out of 3763 females with CD2_BENIGN_CONJUNCTIVA died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_CONJUNCTIVA 0.942 [0.82, 1.08] 0.393
Birth year 0.988 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 471 out of 3295 males with CD2_BENIGN_CONJUNCTIVA died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_CONJUNCTIVA.

N-year risk Females Males
1 0.092% 0.141%
5 0.466% 1.121%
10 1.353% 2.747%
15 2.688% 5.275%
20 5.024% 8.955%

Relationships between endpoints

Index endpoint: CD2_BENIGN_CONJUNCTIVA – Benign neoplasm: Conjunctiva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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