intestinal perforation: Opening or penetration through the wall of the INTESTINES.
Other congenital malformations of intestine
DOID EFO Endpoint Browser PheWeb
Q17_OTHER_CONGEN_MALFO_INTESTINE
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
314 |
4. Check minimum number of eventsNone |
314 |
5. Include endpointsNone |
314 |
6. Filter based on genotype QC (FinnGen only) |
314 |
Control definitions (FinnGen only)
- Control exclude
- Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Q3[8-9]|Q4[0-5]
- Name in latin
- Aliae malformationes congenitae intestini
Similar endpoints
↥List of similar endpoints to
Other congenital malformations of intestine
based on the number of shared cases.
Similar with more cases:
- Other congenital malformations of the digestive system
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3727 | 1773 | 1940 |
| Only index persons | 3073 | 1448 | 1625 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | 0.05 |
| Only index persons | 0.06 | 0.05 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 16.48 | 14.08 | 18.30 |
| Only index persons | 23.09 | 22.17 | 23.91 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 314 | 163 | 151 |
| Unadjusted period prevalence (%) | 0.06 | 0.06 | 0.07 |
| Median age at first event (years) | 45.77 | 44.18 | 47.49 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 283
- Matched controls
- 2828
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q43.0
ICD-10 Finland
Meckel diverticulum
+∞
172.0
147
*
Q43.8
ICD-10 Finland
Other specified congenital malformations of intestine
+∞
48.3
45
*
Q43.1
ICD-10 Finland
Hirschsprung disease
+∞
40.6
38
*
JFB00
NOMESCO Finland
Partial resection of small intestine
98.3
39.0
42
5
JFA73
NOMESCO Finland
Excision of lesion of small intestine
225.2
38.9
39
*
JEA00
NOMESCO Finland
Appendectomy
8.4
24.8
57
82
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
10.5
24.5
49
55
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.7
23.2
147
642
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
15.7
19.1
31
22
Q43.5
ICD-10 Finland
Ectopic anus
+∞
19.0
18
*
UJF32
NOMESCO Finland
Coloscopy
3.4
17.0
100
387
JAH00
NOMESCO Finland
Laparotomy
12.8
17.0
30
26
WX408
NOMESCO Finland
General anesthesy, balanced
3.1
16.3
116
515
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.2
16.1
103
424
P01AB01
ATC
metronidazole; oral, rectal
2.9
15.7
132
652
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
22.6
14.9
21
10
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
14.4
14.5
24
18
TJF80
NOMESCO Finland
Ostomy education
20.5
14.5
21
11
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.5
13.9
52
135
Q43.30
ICD-10 Finland
Template rotation of colon
+∞
13.6
13
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.6
13.1
65
217
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.9
12.1
90
396
Q43.9
ICD-10 Finland
Congenital malformation of intestine, unspecified
+∞
11.5
11
*
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
13.6
10.8
18
14
TPH07
NOMESCO Finland
Cathetrisation of artery
3.5
10.5
52
172
JAH01
NOMESCO Finland
Laparoscopy
6.4
10.4
27
46
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
10.4
63
242
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.8
10.0
73
315
A06AC01
ATC
ispaghula (psylla seeds); oral
2.7
9.7
75
332
K56.2
ICD-10 Finland
Volvulus
31.2
9.5
12
*
Q43.2
ICD-10 Finland
Other congenital functional disorders of colon
+∞
9.4
9
*
Q42.2
ICD-10 Finland
Congenital absence, atresia and stenosis of anus with fistula
+∞
9.4
9
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
9.2
73
329
J01MA02
ATC
ciprofloxacin; systemic
2.3
8.9
109
612
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.8
8.6
28
63
K59.09
ICD-10 Finland
Constipation, unspecified
4.9
8.4
27
60
Q42.0
ICD-10 Finland
Congenital absence, atresia and stenosis of rectum with fistula
+∞
8.4
8
*
7513A
ICD-9 Finland
Other congenital anomalies of digestive system, Hirschsprung's disease and other congenital functional disorders of colon[MORBUS HIRSCHPRUNG]
+∞
8.4
8
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
8.2
72
342
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.7
8.0
58
246
UJD02
NOMESCO Finland
Gastroscopy
5.6
7.9
22
42
WX002
NOMESCO Finland
Sedation and analgesia
2.5
7.8
65
299
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
7.5
125
789
JGB20
NOMESCO Finland
Partial rectosigmoidectomy and abdominoperineal pull-through anastomosis
82.2
7.5
8
*
TJD20
NOMESCO Finland
Change of gastrostomy tube
13.9
7.5
12
9
K59.0
ICD-10 Finland
Constipation
4.5
7.4
25
59
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
7.4
35
112
Q42.3
ICD-10 Finland
Congenital absence, atresia and stenosis of anus without fistula
+∞
7.3
7
*
JFA74
NOMESCO Finland
Laparoscopic excision of lesion of small intestine
+∞
7.3
7
*
K57.1
ICD-10 Finland
Diverticular disease of small intestine without perforation or abscess
16.3
7.3
11
7
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
30.9
7.2
9
*
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
30.9
7.2
9
*
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
3.3
7.2
35
115
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
6.7
56
255
K92.1
ICD-10 Finland
Melaena
4.1
6.5
24
63
JDB00
NOMESCO Finland
Gastrostomy
71.4
6.5
7
*
JF2AB
NOMESCO Finland
Colongraphy with X-ray
18.5
6.3
9
5
K57.0
ICD-10 Finland
Diverticular disease of small intestine with perforation and abscess
+∞
6.3
6
*
6504
FHL
Reconstruction
+∞
6.3
6
*
Q87.26
ICD-10 Finland
VATER association
+∞
6.3
6
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
6.1
26
77
K65.0
ICD-10 Finland
Acute peritonitis
12.9
6.1
10
8
WX882
NOMESCO Finland
High dependency care
3.5
6.1
27
83
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
10.3
6.1
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
197
1211
2.68
15.80
9.4
6.3
12.25
12.99
umol/l
0.17
184
1151
170
981
2.60
15.42
9.5
5.2
35.59
36.26
g/l
0.83
160
920
243
1830
2.45
10.18
12.0
6.8
90.06
84.38
u/l
0.83
233
1711
25
64
4.16
9.06
2.1
1.3
—
—
—
0
0
13
18
7.49
8.91
10.5
1.6
24.31
30.33
umol/l
1.05
13
18
41
149
3.01
8.78
2.2
1.6
—
—
—
0
0
138
868
2.05
8.70
5.7
3.4
—
—
—
0
0
101
571
2.13
8.42
4.3
2.3
—
—
—
0
0
116
701
2.04
8.03
5.0
3.2
0.28
0.32
e6/l
0.13
98
520
79
416
2.20
7.82
3.9
3.1
3.97
2.23
e6/l
0.45
47
234
147
982
1.93
7.51
4.1
2.5
72.62
73.72
nmol/l
0.20
133
888
80
430
2.15
7.49
3.7
3.0
1.90
0.73
e6/l
0.81
49
244
169
1188
1.92
7.35
15.0
7.7
1.21
1.22
mmol/l
0.19
146
1029
49
215
2.52
7.32
17.5
9.7
1.32
1.34
mmol/l
0.05
49
202
119
748
1.95
7.22
3.3
3.2
2.38
2.36
mmol/l
0.58
110
661
158
1098
1.88
7.01
18.2
7.6
1.21
1.22
mmol/l
0.52
143
1013
128
834
1.90
6.91
6.8
3.1
32.97
31.92
u/l
0.15
119
792
203
1537
1.91
6.81
13.1
9.4
4.43
4.02
e9/l
1.28
179
1330
61
305
2.24
6.78
16.7
6.0
1.87
1.42
mmol/l
0.54
48
232
70
372
2.13
6.69
10.0
4.7
0.81
0.82
mmol/l
0.44
65
349
61
309
2.21
6.56
16.9
6.0
5.83
5.76
kpa
0.27
61
299
156
1112
1.80
6.11
5.7
4.1
—
—
—
0
0
66
359
2.06
5.89
2.0
1.9
—
—
—
0
0
11
20
5.66
5.85
8.3
1.4
26.20
19.40
umol/l
0.29
11
20
20
64
3.27
5.29
1.6
1.5
—
—
—
0
0
121
830
1.74
5.19
2.6
1.9
97.57
94.23
pmol/l
0.33
68
426
286
2539
2.42
4.96
28.6
14.3
139.30
139.66
mmol/l
1.72
277
2469
73
436
1.88
4.92
4.7
3.7
458.91
394.94
ng/l
0.08
50
321
286
2545
2.39
4.83
28.7
14.3
3.97
3.97
mmol/l
0.12
278
2467
184
1442
1.67
4.63
10.9
5.4
6.33
6.57
mmol/l
1.11
174
1341
46
242
2.06
4.45
13.7
5.4
1.86
1.27
mmol/l
0.88
36
182
51
280
1.98
4.39
17.7
5.7
5.55
4.69
kpa
1.81
51
270
23
90
2.68
4.32
1.4
1.2
—
—
—
0
0
62
370
1.84
4.16
3.1
3.0
2.44
2.44
mmol/l
0.04
55
324
285
2569
2.18
4.04
24.3
12.5
30.01
22.60
mg/l
2.82
250
1947
41
215
2.04
4.00
4.4
4.3
2.90
7.93
ug/l
2.03
30
173
143
1091
1.57
3.74
4.4
2.7
101.36
104.49
ug/l
0.07
134
1007
26
117
2.33
3.69
2.1
1.7
—
—
—
0
0
46
262
1.89
3.56
2.0
1.8
—
—
—
0
0
152
1192
1.53
3.43
5.3
4.6
0.00
0.00
estimate
0.00
29
210
151
1190
1.52
3.29
4.2
3.2
0.00
0.00
estimate
0.00
29
208
201
1686
1.53
3.24
7.0
3.2
46.49
43.66
u/l
0.16
189
1601
14
49
2.94
3.23
34.8
9.2
81.04
63.93
%
2.25
14
49
18
73
2.55
3.19
2.1
2.1
—
—
—
0
0
43
249
1.84
3.16
17.7
7.6
6.52
7.83
mmol/l
1.10
43
244
41
236
1.85
3.07
9.0
11.2
-0.42
1.08
mmol/l
1.29
35
194
151
1203
1.49
3.05
4.2
3.2
0.00
0.00
estimate
0.00
30
198
76
522
1.60
3.02
3.0
2.3
0.90
1.12
mg/l
0.50
62
398
214
1833
1.53
3.02
5.2
3.9
12.24
10.52
mm/h
0.92
205
1697
44
263
1.78
2.93
2.0
1.8
—
—
—
0
0
16
64
2.58
2.92
2.1
1.7
—
—
—
0
0
9
24
3.83
2.69
6.0
3.4
96.00
98.12
%
—
9
24
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
15
61
2.53
2.66
5.3
6.6
0.28
0.32
u/ml
—
9
37
16
68
2.43
2.60
2.2
2.0
—
—
—
0
0
218
1923
1.44
2.28
3.3
3.4
—
—
—
0
0
52
352
1.57
2.19
2.0
1.7
1207.88
1168.81
nmol/l
0.10
34
257
56
387
1.54
2.15
4.4
3.0
29.68
29.84
s
0.09
56
381
58
404
1.53
2.15
1.8
1.7
415.24
449.61
pmol/l
0.61
50
338
284
2657
1.72
2.14
17.0
9.5
28.34
27.12
u/l
0.30
276
2559
20
104
1.99
2.05
3.8
2.5
28008.78
4365.61
u/l
—
9
35
6
15
4.06
2.05
2.3
1.6
0.91
1.07
g/l
—
6
15
15
70
2.20
2.01
1.7
1.7
—
—
—
0
0
13
57
2.34
2.00
1.2
1.2
—
—
—
0
0
13
57
2.34
2.00
1.2
1.2
—
—
—
0
0
15
71
2.17
1.95
2.0
1.6
269.00
196.40
u/ml
—
7
40
213
1895
1.39
1.95
4.6
3.7
14.85
14.62
pmol/l
0.68
200
1714
6
16
3.80
1.94
2.8
2.0
—
—
—
0
0
37
239
1.62
1.89
17.5
20.8
1.25
1.32
inr
—
8
35
8
28
2.90
1.87
1.6
1.2
—
—
—
0
0
23
132
1.80
1.79
1.4
1.3
—
—
—
0
0
17
88
1.99
1.78
1.5
1.2
—
—
—
0
0
17
89
1.96
1.73
1.5
1.2
—
—
—
0
0
239
2185
1.39
1.72
20.6
11.2
88.56
86.64
ml/min/173m2
0.60
207
1742
5
13
3.89
1.72
4.0
2.2
—
—
—
0
0
14
69
2.08
1.67
1.6
1.7
—
—
—
0
0
15
76
2.02
1.67
2.0
1.6
—
—
—
0
0
10
43
2.37
1.62
1.2
1.2
—
—
—
0
0
10
43
2.37
1.62
2.7
3.7
60.90
57.23
%
—
10
43
10
43
2.37
1.62
2.7
3.7
4.66
4.43
e9/l
—
10
43
14
70
2.05
1.62
1.3
1.3
352.22
303.34
ug/g
—
9
39
7
27
2.63
1.52
1.1
1.6
—
—
—
0
0
244
2255
1.37
1.51
29.2
15.5
13.78
13.50
%
2.10
239
2219
6
22
2.76
1.44
1.5
1.5
—
—
—
0
0
110
917
1.31
1.44
4.2
3.2
—
—
—
0
0
76
602
1.35
1.41
5.2
3.4
0.00
0.00
estimate
0.50
28
205
9
40
2.29
1.41
1.3
1.5
—
—
—
0
0
12
60
2.04
1.40
2.1
2.4
—
—
—
0
0
9
41
2.23
1.38
1.8
1.6
—
—
—
0
0
26
168
1.60
1.36
4.2
2.5
70.44
68.38
ml/min/173m2
—
9
76
0
41
0.00
1.32
0.0
1.4
—
7.48
—
0
22
8
34
2.39
1.30
1.1
1.5
—
—
—
0
0
5
18
2.81
1.29
1.8
1.2
—
—
—
0
0
8
35
2.32
1.27
2.5
1.4
—
—
—
0
0
260
2449
1.36
1.24
27.3
14.0
39.67
40.19
%
0.55
205
1910
10
49
2.08
1.23
1.3
1.5
—
—
—
0
0
8
37
2.19
1.22
2.0
3.1
—
—
—
0
0
5
111
0.44
1.15
1.0
1.7
—
—
—
0
0
12
65
1.88
1.15
1.2
1.5
—
—
—
0
0
11
58
1.93
1.13
1.4
2.2
—
—
—
0
0
8
40
2.03
1.13
2.0
2.8
0.22
0.19
e9/l
—
8
31
5
21
2.40
1.09
1.6
1.3
—
—
—
0
0
7
33
2.15
1.06
1.1
1.5
—
—
—
0
0
7
34
2.08
1.03
1.3
1.6
—
—
—
0
0
15
91
1.68
1.02
1.5
1.6
—
—
—
0
0
7
35
2.02
1.00
1.4
1.4
—
—
—
0
0
23
157
1.50
0.99
15.7
3.4
1.24
1.22
mmol/l
0.41
17
135
45
349
1.34
0.97
1.4
1.4
—
—
—
0
0
7
36
1.97
0.97
1.3
1.5
—
—
—
0
0
7
36
1.97
0.97
1.0
1.2
—
—
—
0
0
72
599
1.26
0.93
3.0
3.5
1996.26
993.75
ng/l
0.53
58
501
6
28
2.16
0.92
2.2
1.4
403.17
732.17
pmol/l
—
6
23
28
203
1.42
0.91
1.0
1.0
—
—
—
0
0
225
2120
1.22
0.82
5.8
5.4
38.42
39.46
mmol/mol
0.98
214
1981
0
24
0.00
0.79
0.0
1.8
—
7.15
—
0
11
6
34
1.78
0.76
1.8
1.4
—
—
—
0
0
46
372
1.28
0.76
1.2
1.3
16.86
7.72
u/ml
0.54
17
135
5
24
2.10
0.75
1.4
1.2
—
—
—
0
0
94
826
1.20
0.73
3.5
3.4
25.80
38.03
ng/l
0.68
59
532
5
25
2.02
0.73
7.8
13.0
1157.20
1436.28
nmol/l
—
5
25
240
2290
1.20
0.69
5.4
4.3
1.76
1.89
mu/l
1.28
228
2090
7
42
1.68
0.69
2.1
2.8
620.29
553.58
e6/l
—
7
31
42
341
1.27
0.68
1.8
1.9
1.40
1.46
%
0.24
35
311
5
28
1.80
0.66
3.8
2.9
26.32
19.40
ug/l
—
5
28
8
49
1.65
0.62
1.3
1.7
—
—
—
0
0
61
524
1.20
0.61
3.6
4.3
22.13
21.70
%
0.08
27
227
8
52
1.55
0.60
1.6
1.4
—
—
—
0
0
231
2208
1.17
0.59
4.2
3.7
1.31
1.27
mmol/l
0.28
220
2043
0
23
0.00
0.58
0.0
3.0
—
—
—
0
0
83
739
1.17
0.55
1.4
1.5
3.68
1.39
u/ml
0.60
25
178
11
74
1.50
0.54
1.4
1.7
—
—
—
0
0
6
39
1.55
0.53
1.2
1.1
—
—
—
0
0
11
153
0.71
0.47
1.4
1.5
—
—
—
0
0
8
56
1.44
0.43
1.1
1.5
—
—
—
0
0
8
57
1.41
0.42
1.3
2.7
37.49
150.25
mg/l
—
8
45
8
57
1.41
0.42
1.3
2.7
29.26
30.14
mg/l
—
8
45
0
15
0.00
0.41
0.0
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
5
34
1.48
0.40
2.4
1.3
0.46
0.47
nmol/l
—
5
29
14
106
1.34
0.40
1.5
1.5
—
—
—
0
0
21
170
1.25
0.38
1.6
1.3
—
—
—
0
0
5
78
0.64
0.36
1.4
1.4
—
—
—
0
0
5
78
0.64
0.36
1.4
1.4
—
—
—
0
0
5
78
0.64
0.36
1.4
1.4
—
—
—
0
0
44
387
1.16
0.36
2.5
2.8
0.57
0.83
ug/l
1.83
30
245
74
676
1.12
0.35
4.5
4.8
2.00
2.16
ug/l
0.14
66
596
12
91
1.33
0.34
1.2
1.3
—
—
—
0
0
45
400
1.15
0.32
1.3
1.3
50.32
27.67
iu/ml
0.26
11
126
70
644
1.11
0.30
1.9
1.7
—
—
—
0
0
7
57
1.23
0.29
1.7
1.2
—
—
—
0
0
68
627
1.11
0.28
4.0
4.1
2.63
10.29
mg/mmol
3.30
44
406
69
637
1.11
0.28
2.1
1.7
1.32
1.40
mmol/l
0.39
62
542
9
72
1.26
0.26
2.1
1.3
—
—
—
0
0
62
574
1.10
0.24
3.8
3.0
338.60
6294.24
umol/l
2.20
55
498
25
218
1.16
0.24
3.4
3.1
—
—
—
0
0
239
2341
1.09
0.23
4.9
4.5
2.65
2.76
mmol/l
1.20
228
2176
7
91
0.76
0.23
1.4
1.1
—
10.27
—
0
13
236
2312
1.08
0.22
4.6
4.1
4.43
4.62
mmol/l
2.09
226
2155
5
41
1.22
0.22
1.6
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
8
102
0.78
0.21
1.4
2.3
51.25
41.61
u/l
—
8
95
5
43
1.17
0.21
2.4
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
6
51
1.18
0.19
1.5
1.2
—
—
—
0
0
234
2297
1.07
0.19
4.3
4.1
1.36
1.44
mmol/l
2.53
225
2129
7
62
1.13
0.17
1.6
1.4
—
—
—
0
0
20
178
1.13
0.15
1.1
1.2
51.64
151.34
iu/ml
—
8
66
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
6
55
1.09
0.09
1.0
1.1
—
—
—
0
0
5
62
0.80
0.08
3.2
1.6
—
—
—
0
0
23
246
0.93
0.08
6.3
6.5
—
—
—
0
0
6
73
0.82
0.07
1.5
1.6
—
—
—
0
0
9
84
1.07
0.07
1.4
2.1
—
—
—
0
0
14
129
1.09
0.05
7.3
2.4
0.11
0.14
e6/l
0.12
14
121
16
170
0.94
0.04
1.9
1.8
—
—
—
0
0
42
410
1.03
0.03
1.9
2.3
—
—
—
0
0
22
213
1.04
0.01
2.0
2.0
—
—
—
0
0
225
2249
1.00
0.00
4.6
4.1
5.82
5.88
mmol/l
0.32
209
2061
10
103
0.97
0.00
1.6
1.3
—
—
—
0
0
10
105
0.95
0.00
1.2
1.1
—
—
—
0
0
23
225
1.02
0.00
1.6
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
7
77
0.91
0.00
1.9
2.7
5642.86
199.95
e6/l
—
7
60
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
37
370
1.00
0.00
1.9
2.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
7
77
0.91
0.00
1.9
2.6
66.57
2.75
e6/l
—
7
57
6
65
0.92
0.00
1.8
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint Q17_OTHER_CONGEN_MALFO_INTESTINE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_INTESTINE | 1.262 [1.0, 1.59] | 0.047 |
| Birth year | 0.992 [0.98, 1.0] | 0.057 |
During the follow-up period (1.1.1998 — 31.12.2019), 156 out of 1498 females with Q17_OTHER_CONGEN_MALFO_INTESTINE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| Q17_OTHER_CONGEN_MALFO_INTESTINE | 1.574 [1.26, 1.97] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.035 |
During the follow-up period (1.1.1998 — 31.12.2019), 193 out of 1619 males with Q17_OTHER_CONGEN_MALFO_INTESTINE died.
Mortality risk
Mortality risk for people of age
years, who have Q17_OTHER_CONGEN_MALFO_INTESTINE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.114% | 0.398% |
| 5 | 0.63% | 2.107% |
| 10 | 1.673% | 5.054% |
| 15 | 3.275% | 9.363% |
| 20 | 5.698% | 15.628% |
Relationships between endpoints
↥Index endpoint: Q17_OTHER_CONGEN_MALFO_INTESTINE – Other congenital malformations of intestine
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data