Other congenital malformations of the digestive system

Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q38-Q45
  • Cause of death: ICD-10 Q38-Q45

2 out of 7 registries used, show all original rules.

1734

4. Check minimum number of events

None

1734

5. Include endpoints

1734

6. Filter based on genotype QC (FinnGen only)

1734

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q
Name in latin
Aliae malformationes congenitae systematis digestorii

Similar endpoints

List of similar endpoints to Other congenital malformations of the digestive system based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 34635 12697 21890
Only index persons 22487 8662 13825
Unadjusted period prevalence (%)
Whole population 0.52 0.36 0.61
Only index persons 0.45 0.32 0.53
Median age at first event (years)
Whole population 4.64 5.19 4.19
Only index persons 6.15 7.32 5.43

-FinnGen-

Key figures

All Female Male
Number of individuals 1734 936 798
Unadjusted period prevalence (%) 0.33 0.32 0.35
Median age at first event (years) 38.63 39.32 37.83

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1504
Matched controls
14967
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q38.1
ICD-10 Finland
Ankyloglossia
529.8
323.0
398
10
EJC20
NOMESCO Finland
Operation on frenulum in mouth
175.0
266.4
274
19
Q44.6
ICD-10 Finland
Cystic disease of liver
+∞
203.5
191
*
Q40.9
ICD-10 Finland
Congenital malformation of upper alimentary tract, unspecified
+∞
178.4
168
*
Q43.0
ICD-10 Finland
Meckel diverticulum
1659.7
154.6
148
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.4
131.3
625
2095
Q39.6
ICD-10 Finland
Diverticulum of oesophagus
738.8
72.6
71
*
K76.80
ICD-10 Finland
Hepatic cyst
44.1
61.5
76
18
Q43.8
ICD-10 Finland
Other specified congenital malformations of intestine
+∞
48.1
46
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.5
47.2
147
287
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
46.7
331
1324
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
28.5
42.7
58
21
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
41.3
607
3537
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.6
40.6
197
594
JAH00
NOMESCO Finland
Laparotomy
7.8
39.8
94
126
Q43.1
ICD-10 Finland
Hirschsprung disease
+∞
39.7
38
*
JFA73
NOMESCO Finland
Excision of lesion of small intestine
204.1
38.9
40
*
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
29.7
38.7
52
18
UJF32
NOMESCO Finland
Coloscopy
2.5
37.3
363
1718
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
13.5
37.0
65
50
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
34.2
493
2790
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
30.7
33.9
45
15
Q44.21
ICD-10 Finland
Atresia of extrahepatic bile ducts
+∞
33.4
32
*
K22.5
ICD-10 Finland
Diverticulum of oesophagus, acquired
41.8
33.1
41
10
Q39.11
ICD-10 Finland
Atresia of oesophagus with broncho-oesophageal fistula
+∞
31.3
30
*
JJA31
NOMESCO Finland
Laparoscopic marsupialisation of cyst of liver
+∞
31.3
30
*
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
10.7
31.2
61
59
JFB00
NOMESCO Finland
Partial resection of small intestine
11.7
30.6
57
50
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
30.4
594
3755
Q44.29
ICD-10 Finland
Atresia of bile ducts
+∞
29.2
28
*
JKD50
NOMESCO Finland
Hepatoportoenterostomy
+∞
29.2
28
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.3
28.3
155
509
Q40.1
ICD-10 Finland
Congenital hiatus hernia
+∞
28.1
27
*
127
Kela drug reimbursment
Transplant complication
6.4
27.7
74
119
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
27.7
376
2041
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
6.8
27.4
70
106
Z94.4
ICD-10 Finland
Liver transplant status
19.9
27.4
41
21
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.2
26.8
153
518
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
26.5
253
1164
K83.0
ICD-10 Finland
Cholangitis
10.7
26.3
51
49
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
7.6
25.7
61
83
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
6.2
24.4
67
112
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.5
24.1
210
917
Q45.38
ICD-10 Finland
Other congenital malformations of pancreas and pancreatic duct
+∞
24.0
23
*
Q42.2
ICD-10 Finland
Congenital absence, atresia and stenosis of anus with fistula
+∞
22.9
22
*
Q41.0
ICD-10 Finland
Congenital absence, atresia and stenosis of duodenum
+∞
22.9
22
*
A11CC03
ATC
alfacalcidol; systemic
5.4
22.9
70
134
JJ5KT
NOMESCO Finland
Sclerotherapy of liver cyst
232.1
22.6
23
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
6.1
22.1
61
103
Z94.0
ICD-10 Finland
Kidney transplant status
6.7
21.8
56
86
JJC00
NOMESCO Finland
Allogenic transplantation of liver
31.5
21.5
28
9
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
7.6
21.4
50
67
UGC02
NOMESCO Finland
Rigid bronchoscopy
10.7
21.3
41
39
J01MA02
ATC
ciprofloxacin; systemic
1.8
20.8
452
2878
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
3.3
20.5
108
345
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
19.8
173
753
L04AX01
ATC
azathioprine; systemic
3.5
19.5
92
270
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.6
19.2
88
252
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
18.9
118
422
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.6
18.8
140
558
Q39.10
ICD-10 Finland
Atresia of oesophagus with broncho-oesophageal fistula
+∞
18.7
18
*
Q42.3
ICD-10 Finland
Congenital absence, atresia and stenosis of anus without fistula
+∞
18.7
18
*
Q43.5
ICD-10 Finland
Ectopic anus
+∞
18.7
18
*
Q39.0
ICD-10 Finland
Atresia of oesophagus without fistula
+∞
18.7
18
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.8
18.1
61
131
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
18.1
304
1756
TJD20
NOMESCO Finland
Change of gastrostomy tube
9.2
17.9
37
41
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
67.1
17.7
20
*
Q40.0
ICD-10 Finland
Congenital hypertrophic pyloric stenosis
+∞
17.7
17
*
Q44.4
ICD-10 Finland
Choledochal cyst
+∞
17.7
17
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
17.7
200
986
A05AA02
ATC
ursodeoxycholic acid; oral
5.6
17.5
51
93
RD210
NOMESCO Finland
NA
3.3
17.4
88
273
R13
ICD-10 Finland
Dysphagia
3.1
17.1
97
326
A02BC05
ATC
esomeprazole; systemic
1.7
16.7
448
3001
JCA60
NOMESCO Finland
Transcervical excision of diverticulum of oesophagus
+∞
16.7
16
*
Q44.20
ICD-10 Finland
Atresia of intrahepatic bile ducts
+∞
16.7
16
*
Q42.0
ICD-10 Finland
Congenital absence, atresia and stenosis of rectum with fistula
+∞
16.7
16
*
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
11.7
16.5
30
26
N02AX02
ATC
tramadol; systemic, rectal
1.7
16.4
463
3145
P01AB01
ATC
metronidazole; oral, rectal
1.7
15.9
445
3009
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
15.9
216
1151
A02BC02
ATC
pantoprazole; systemic
1.6
15.7
722
5545
Q45.8
ICD-10 Finland
Other specified congenital malformations of digestive system
+∞
15.6
15
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
15.4
295
1777
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.6
15.3
53
118
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
20.2
15.1
22
11
A02BC01
ATC
omeprazole; systemic
1.7
14.8
321
2010
UJD02
NOMESCO Finland
Gastroscopy
3.2
14.5
78
254
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.4
14.4
125
542
H02AB04
ATC
methylprednisolone; systemic
2.1
14.3
177
905
R4110
NOMESCO Finland
Physiotherapy
1.7
14.3
372
2450
L04AA06
ATC
mycophenolic acid; systemic
4.5
14.3
50
113
WX402
NOMESCO Finland
General anaesthesia
1.8
14.0
271
1631
L04AD01
ATC
ciclosporin; systemic
4.1
14.0
54
134
A03FA02
ATC
cisapride; oral, rectal
2.6
13.8
104
418
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
10.5
13.7
26
25
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.7
13.7
59
162
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
5.6
13.6
39
71
602
Kela drug reimbursment
Children's severe malnutrition
4.2
13.6
51
124
Q43.30
ICD-10 Finland
Template rotation of colon
+∞
13.5
13
*
JJ5AT
NOMESCO Finland
NA
34.2
13.5
17
5
R50.9
ICD-10 Finland
Fever, unspecified
1.8
13.5
258
1547
UJC12
NOMESCO Finland
Flexible oesophagoscopy
10.1
13.4
26
26
K92.1
ICD-10 Finland
Melaena
2.9
13.3
82
292
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
6.2
13.3
35
57
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.1
13.2
51
127
WX882
NOMESCO Finland
High dependency care
2.4
13.2
110
468
JAH01
NOMESCO Finland
Laparoscopy
3.2
13.1
70
227
JFC00
NOMESCO Finland
Entero-enterostomy
40.2
13.1
16
*
A02BC03
ATC
lansoprazole; oral
1.7
13.0
299
1893
JEA00
NOMESCO Finland
Appendectomy
2.6
12.8
94
373
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.2
12.8
48
117
Q44.3
ICD-10 Finland
Congenital stenosis and stricture of bile ducts
+∞
12.5
12
*
Q44.1
ICD-10 Finland
Other congenital malformations of gallbladder
+∞
12.5
12
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
6.2
12.2
32
52
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
5.2
12.2
37
72
TK800
NOMESCO Finland
Hemodialysis
4.1
11.9
46
115
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
11.9
277
1757
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.8
11.9
77
283
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
11.7
125
597
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
11.7
272
1723
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.5
11.7
53
153
75020
ICD-8 Finland
Other congenital anomalies of upper alimentary tract, Atresia oesophagi
+∞
11.4
11
*
Q43.9
ICD-10 Finland
Congenital malformation of intestine, unspecified
+∞
11.4
11
*
A12AA04
ATC
calcium carbonate; oral
4.3
11.4
41
96
WX002
NOMESCO Finland
Sedation and analgesia
1.8
11.3
220
1321
JDB10
NOMESCO Finland
Percutaneous gastrostomy
5.6
11.3
32
58
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.4
11.0
53
161
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
15.5
10.8
17
11
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.1
10.6
122
606
J01DB01
ATC
cefalexin; oral
1.5
10.5
1075
9412
5AB14
NOMESCO Finland
NA
10.1
10.5
20
20
R4190
NOMESCO Finland
Nutritional therapy
2.1
10.5
114
551
Q38.08
ICD-10 Finland
Congenital malformations of lips, not elsewhere classified
+∞
10.4
10
*
Q39.9
ICD-10 Finland
Congenital malformation of oesophagus, unspecified
+∞
10.4
10
*
JCE31
NOMESCO Finland
Treatment esophageal atresia
+∞
10.4
10
*
Q45.30
ICD-10 Finland
Ectopic pancreas
+∞
10.4
10
*
Q44.0
ICD-10 Finland
Agenesis, aplasia and hypoplasia of gallbladder
+∞
10.4
10
*
Q41.9
ICD-10 Finland
Congenital absence, atresia and stenosis of small intestine, part unspecified
+∞
10.4
10
*
K00.81
ICD-10 Finland
Color changes in the teeth caused by biliary anomalies
+∞
10.4
10
*
Q44.78
ICD-10 Finland
Other congenital malformations of the liver
+∞
10.4
10
*
TJF80
NOMESCO Finland
Ostomy education
5.3
10.2
30
57
UKC02
NOMESCO Finland
Cystoscopy
1.8
10.2
168
955
RS220
NOMESCO Finland
NA
3.8
10.2
42
113
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.8
10.2
42
113
A02BC04
ATC
rabeprazole; oral
2.3
10.1
95
430
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
10.1
97
442
H02AB09
ATC
hydrocortisone; systemic
2.8
10.0
63
229
JDB00
NOMESCO Finland
Gastrostomy
10.1
10.0
19
19
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.6
10.0
74
297
TBW99
NOMESCO Finland
Other minor procedure in endocrine surgery
3.8
10.0
41
110
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
5.3
9.9
29
55
K56.7
ICD-10 Finland
Ileus, unspecified
5.5
9.9
28
51
WX110
NOMESCO Finland
Local anesthesy
1.4
9.9
959
8248
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
9.9
275
1823
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
9.9
243
1561
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
2.8
9.8
61
220
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.3
9.8
88
392
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
9.8
130
682
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
9.6
440
3275
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
9.6
742
6107
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.3
9.5
86
382
K56.2
ICD-10 Finland
Volvulus
11.4
9.5
17
15
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
15.0
9.5
15
10
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
4.8
9.4
30
63
1304
FHL
Esophagogastroduodenoscopy and other therapeutic procedure
100.1
9.4
10
*
Q38.68
ICD-10 Finland
Congenital malformation of mouth NOS
100.1
9.4
10
*
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
6.6
9.4
23
35
JD1EE
NOMESCO Finland
Ultrasound examination of gastro-oesophageal reflux
30.0
9.4
12
*
UDC00
NOMESCO Finland
Ear microscopy
2.1
9.4
111
558
JJ1AT
NOMESCO Finland
Puncture of lesion of liver with ultrasound guidance
+∞
9.4
9
*
Q43.2
ICD-10 Finland
Other congenital functional disorders of colon
+∞
9.4
9
*
Q44.75
ICD-10 Finland
Focal nodular hypoplasia of the liver
+∞
9.4
9
*
Q39.3
ICD-10 Finland
Congenital stenosis and stricture of oesophagus
+∞
9.4
9
*
7503C
ICD-9 Finland
Other congenital anomalies of upper alimentary tract, Tracheooesophageal fistula, oesophageal atresia and stenosis[RUOKATORVIATRESIA ALAFISTELEINEEN]
+∞
9.4
9
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
2.0
9.4
121
628
Z98.8
ICD-10 Finland
Other specified postsurgical states
4.1
9.3
35
87
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.7
9.3
185
1116
Z31.5
ICD-10 Finland
Genetic counselling
2.2
9.2
94
442
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.7
9.2
213
1345
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
4.7
9.2
30
65
C03CA01
ATC
furosemide; systemic
1.6
9.1
258
1716
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.6
9.1
39
109
ZXA10
NOMESCO Finland
Bilateral
1.6
9.1
236
1536
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.1
9.0
27
53
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
5.4
9.0
26
49
JJC10
NOMESCO Finland
Allogenic partial transplantation of liver
36.7
9.0
11
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
8.8
264
1782
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.2
8.8
44
139
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
8.8
59
223
K29.7
ICD-10 Finland
Gastritis, unspecified
3.1
8.8
47
156
T18.1
ICD-10 Finland
Foreign body in oesophagus
5.6
8.7
24
43
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
7.2
8.7
20
28
N02BE01
ATC
paracetamol; systemic, rectal
1.4
8.7
1019
8958
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
6.6
8.6
21
32
K59.0
ICD-10 Finland
Constipation
2.3
8.6
77
341
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
16.3
8.5
13
8
-
ICD-10 Finland
NA
3.9
8.5
33
85
Q38.7
ICD-10 Finland
Pharyngeal pouch
90.0
8.4
9
*
GD1RA
NOMESCO Finland
Dynamic X-ray examination of respiratory organs with convetional X-ray picture
12.8
8.3
14
11
JK3AN
NOMESCO Finland
Biliary tract isotope imaging
+∞
8.3
8
*
JFA74
NOMESCO Finland
Laparoscopic excision of lesion of small intestine
+∞
8.3
8
*
Q38.58
ICD-10 Finland
Congenital malformation of palate NOS
+∞
8.3
8
*
Q39.19
ICD-10 Finland
Atresia of oesophagus with tracheo/broncho-oesophageal fistula
+∞
8.3
8
*
Q39.88
ICD-10 Finland
Other congenital malformations of oesophagus
+∞
8.3
8
*
7513A
ICD-9 Finland
Other congenital anomalies of digestive system, Hirschsprung's disease and other congenital functional disorders of colon[MORBUS HIRSCHPRUNG]
+∞
8.3
8
*
Q41.1
ICD-10 Finland
Congenital absence, atresia and stenosis of jejunum
+∞
8.3
8
*
Q42.1
ICD-10 Finland
Congenital absence, atresia and stenosis of rectum without fistula
+∞
8.3
8
*
JGC40
NOMESCO Finland
Anorectal repair of anal atresia
+∞
8.3
8
*
ZXA00
NOMESCO Finland
Right side
1.5
8.3
286
1993
JN4BD
NOMESCO Finland
Extensive body CT
2.0
8.3
109
570
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.9
8.3
115
614
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
8.3
146
848
A07AA02
ATC
nystatin; oral
2.3
8.2
70
305
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.4
8.2
66
279
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
4.9
8.2
25
51
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.6
8.2
221
1455
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
3.0
8.1
44
148
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.7
8.1
26
56
7531A
ICD-9 Finland
Congenital anomalies of urinary system, Cystic kidney disease
33.3
8.1
10
*
AB4AE
NOMESCO Finland
Spinal ultrasound examination
33.3
8.1
10
*
H52.2
ICD-10 Finland
Astigmatism
2.9
8.0
46
159
ZX120
NOMESCO Finland
Intravenous
1.8
8.0
126
707
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
4.6
8.0
26
57
DCA10
NOMESCO Finland
Paracentesis of tympanic membrane
2.8
7.9
47
168
SPAT1153
SPAT
Removal of sutures
1.5
7.9
340
2484
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
7.9
228
1523
K22.2
ICD-10 Finland
Oesophageal obstruction
6.6
7.9
19
29
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
6.6
7.9
19
29
UJK02
NOMESCO Finland
ERCP
3.7
7.8
32
87
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
7.8
87
429
JJA20
NOMESCO Finland
Open biopsy of liver
10.8
7.8
14
13
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
10.8
7.8
14
13
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
4.2
7.8
28
68
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
4.8
7.7
24
50
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.3
7.7
71
319
B03XA02
ATC
darbepoetin alfa; parenteral
4.3
7.7
27
64
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.7
7.7
50
189
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
5.3
7.7
22
42
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.9
7.6
20
34
K03.66
ICD-10 Finland
Tooth plaque
1.8
7.6
134
779
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
7.6
78
369
JFF26
NOMESCO Finland
Sigmoidostomy
18.3
7.6
11
6
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
11.8
7.6
13
11
N03AX11
ATC
topiramate; oral
2.9
7.5
44
156
EMB30
NOMESCO Finland
Adenotomy
1.8
7.4
121
684
SPAT1301
SPAT
No procedures
1.4
7.4
417
3201
JGB20
NOMESCO Finland
Partial rectosigmoidectomy and abdominoperineal pull-through anastomosis
80.0
7.4
8
*
JDH60
NOMESCO Finland
Pyloromyotomy
80.0
7.4
8
*
JCA35
NOMESCO Finland
Endoscopic contact coagulation in oesophagus
80.0
7.4
8
*
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.0
7.4
92
473
4AA09
NOMESCO Finland
NA
7.6
7.4
16
21
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
7.3
566
4586
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.8
7.3
29
77
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.6
7.3
51
200
Q40.8
ICD-10 Finland
Other specified congenital malformations of upper alimentary tract
+∞
7.3
7
*
1323
FHL
Esophagoscopy and dilatation
+∞
7.3
7
*
Q38.80
ICD-10 Finland
Congenital nasopharyngeal dysmotility
+∞
7.3
7
*
Q45.1
ICD-10 Finland
Annular pancreas
+∞
7.3
7
*
V03AE02
ATC
sevelamer; oral
9.4
7.3
14
15
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
7.2
103
558
K56.0
ICD-10 Finland
Paralytic ileus
6.2
7.2
18
29
JHD00
NOMESCO Finland
Anal dilatation
6.2
7.2
18
29
JBC00
NOMESCO Finland
Gastro-oesophageal antireflux operation
15.7
7.2
11
7
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.8
7.2
43
155
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
7.2
461
3619
A06AD11
ATC
lactulose; oral
1.7
7.1
146
887
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.7
7.1
148
906
Q87.26
ICD-10 Finland
VATER association
30.0
7.1
9
*
JHA10
NOMESCO Finland
Biopsy of anal canal
30.0
7.1
9
*
C08CA01
ATC
amlodipine; oral
1.5
7.1
311
2273
N05BA01
ATC
diazepam; systemic, rectal
1.7
7.1
141
853
A02BA02
ATC
ranitidine; systemic
1.6
7.1
180
1163
AA1AD
NOMESCO Finland
CT of head and brain
1.5
7.1
232
1594
N03AX12
ATC
gabapentin; oral
1.7
7.1
144
877
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
12.0
7.1
12
10
137
Kela drug reimbursment
Uraemia requiring dialysis
4.5
7.0
23
51
XF602
NOMESCO Finland
Bloodpressure monitoring
4.0
7.0
26
65
V03AG01
ATC
sodium cellulose phosphate; systemic
6.0
7.0
18
30
K83.1
ICD-10 Finland
Obstruction of bile duct
5.6
7.0
19
34
L04AA01
ATC
[U] ciclosporin; systemic
3.9
7.0
27
70
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.9
7.0
101
547
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.4
7.0
56
237
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
10.0
7.0
13
13
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
4.7
7.0
22
47
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.8
7.0
114
648
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.7
7.0
128
755
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
3.3
6.9
33
102
KC1JB
NOMESCO Finland
Miktiocystography with X-ray
6.3
6.9
17
27
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.8
6.9
124
727
TJW99
NOMESCO Finland
Other minor procedure in gastrointestinal endoscopy
13.8
6.9
11
8
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.9
6.9
98
532
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.5
6.8
49
197
S18
ICPC
Laceration/cut
1.4
6.8
481
3835
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.8
303
2222
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
9.3
6.8
13
14
RS190
NOMESCO Finland
NA
40.0
6.7
8
*
R62.0
ICD-10 Finland
Delayed milestone
2.4
6.7
54
229
GD1AD
NOMESCO Finland
Thorax CT examination
2.4
6.7
52
218
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
7.2
6.7
15
21
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.1
6.7
24
59
N18.0
ICD-10 Finland
End-stage renal disease
4.4
6.6
22
50
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.0
6.6
86
450
B05DA
ATC
Isotonic solutions
5.2
6.6
19
37
JF2AB
NOMESCO Finland
Colongraphy with X-ray
7.8
6.6
14
18
1240
FHL
Bronchoscopy
7.8
6.6
14
18
UJF92
NOMESCO Finland
Capsular endoscopy
2.8
6.6
39
140
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.2
6.5
61
279
QBE30
NOMESCO Finland
Excision and repair of surgical scar in trunk
8.7
6.5
13
15
WX892
NOMESCO Finland
Monitored bed care
1.8
6.5
108
619
A09AA02
ATC
multienzymes (lipase, protease etc.)
3.2
6.5
31
97
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
2.3
6.4
55
242
UJF30
NOMESCO Finland
Ileoscopy through colon
1.8
6.4
100
560
7516D
ICD-9 Finland
Other congenital anomalies of digestive system, Anomalies of gallbladder, bile ducts and liver[HEPAR POLYCYSTICUM]
69.7
6.4
7
*
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
2.6
6.4
45
178
Q61.1
ICD-10 Finland
Polycystic kidney, autosomal recessive
14.3
6.4
10
7
SPAT1101
SPAT
Orthostatic test
2.5
6.4
48
196
L90.5
ICD-10 Finland
Scar conditions and fibrosis of skin
4.9
6.3
19
39
K65.0
ICD-10 Finland
Acute peritonitis
4.4
6.3
21
48
Q35.1
ICD-10 Finland
Cleft hard palate
8.1
6.3
13
16
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
6.3
110
642
K65.9
ICD-10 Finland
Peritonitis, unspecified
11.0
6.3
11
10
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.4
6.3
51
219
JFB13
NOMESCO Finland
Plastic repair of small intestine with lengthening
+∞
6.2
6
*
Q42.9
ICD-10 Finland
Congenital absence, atresia and stenosis of large intestine, part unspecified
+∞
6.2
6
*
6504
FHL
Reconstruction
+∞
6.2
6
*
Q44.5
ICD-10 Finland
Other congenital malformations of bile ducts
+∞
6.2
6
*
JEW96
NOMESCO Finland
Other operation on appendix
+∞
6.2
6
*
75120
ICD-8 Finland
Other congenital anomalies of digestive system, Atresia ani inferioris cum fistula
+∞
6.2
6
*
D23
ICPC
Hepatomegaly
+∞
6.2
6
*
Q38.2
ICD-10 Finland
Macroglossia
+∞
6.2
6
*
Q45.0
ICD-10 Finland
Agenesis, aplasia and hypoplasia of pancreas
+∞
6.2
6
*
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
6.2
29
89
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
26.6
6.2
8
*
N03AX16
ATC
pregabalin; oral
1.5
6.2
215
1496
N18.8
ICD-10 Finland
Other chronic renal failure
2.7
6.2
40
150
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
4.5
6.1
20
45
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
5.7
6.1
16
28
R03AC02
ATC
salbutamol; inhalant
1.3
6.1
694
5915
Q62.0
ICD-10 Finland
Congenital hydronephrosis
7.7
6.1
13
17
Q21.09
ICD-10 Finland
Ventricular septal defect NOS
4.7
6.1
19
41
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.1
610
5104
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.9
6.1
35
123
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
3.9
6.0
23
60
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.7
6.0
24
65
TQW40
NOMESCO Finland
Remowal of suture of skin
2.0
6.0
72
368
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.7
6.0
118
712
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
10.0
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
889
5130
2.48
74.11
10.9
5.5
36.12
36.23
g/l
0.24
853
4802
967
6216
2.24
57.50
12.3
6.4
13.31
14.56
umol/l
0.91
918
5847
663
3680
2.28
56.28
3.9
2.5
64.74
56.92
u/l
0.65
621
3402
74
92
8.30
55.32
45.1
41.7
6.75
6.96
ug/l
0.36
69
82
324
1322
2.77
53.32
6.6
2.9
0.21
0.21
g/l
0.47
312
1248
79
116
7.04
51.12
7.6
3.0
22.49
26.54
umol/l
2.31
79
116
571
3141
2.20
48.02
5.4
3.4
—
—
—
0
0
321
1382
2.61
47.04
17.1
10.6
7.65
7.60
mmol/l
0.06
312
1341
235
886
2.89
44.42
5.3
3.4
—
—
—
0
0
350
1636
2.41
42.68
16.1
10.0
—
—
—
0
0
53
63
8.59
41.02
3.6
3.6
—
—
—
0
0
709
4453
1.99
40.14
10.3
8.1
1.15
1.20
inr
0.95
164
1310
1241
9461
2.07
39.72
12.8
6.9
98.08
89.20
u/l
3.75
1200
8870
64
100
6.56
39.04
33.4
35.4
143.20
135.69
ug/l
0.24
56
90
68
115
6.07
38.38
2.9
1.4
—
—
—
0
0
330
1570
2.34
38.31
14.8
3.6
6.82
7.89
umol/l
0.72
304
1329
243
1007
2.63
38.00
10.0
5.6
88.50
73.02
ng/l
1.63
235
920
541
3152
2.03
37.36
6.2
4.2
—
—
—
0
0
921
6466
1.89
36.02
16.3
8.4
1.21
1.22
mmol/l
2.77
840
5614
567
3418
1.96
35.12
7.4
3.9
7.39
7.40
ph
0.52
74
655
355
1815
2.19
34.32
13.5
7.0
5.71
5.81
kpa
1.44
349
1761
353
1804
2.19
34.15
13.6
7.0
1.18
1.44
mmol/l
0.84
292
1436
318
1560
2.26
34.01
1.6
1.2
—
—
—
0
0
639
4043
1.90
34.00
4.1
2.6
—
—
—
0
0
859
5979
1.85
33.72
17.0
8.2
1.21
1.22
mmol/l
2.87
812
5496
563
3448
1.92
32.85
12.6
5.1
88.48
89.12
%
0.26
550
3376
1097
8279
1.86
32.74
12.8
9.7
4.11
3.87
e9/l
2.27
987
7110
419
2334
2.03
32.06
4.1
3.0
1.06
0.97
e6/l
0.15
293
1312
158
570
2.93
32.05
9.8
6.6
0.66
0.65
%
0.16
153
557
380
2049
2.08
31.75
5.9
3.7
30.15
30.39
s
0.36
374
1996
385
2089
2.07
31.61
16.8
8.1
1.18
1.19
mmol/l
0.15
374
1953
482
2839
1.95
31.34
4.1
2.9
4.90
6.43
e6/l
1.49
442
2503
274
1306
2.29
31.21
12.3
6.3
—
—
—
0
0
225
987
2.45
30.94
9.5
9.5
118.16
121.78
g/l
1.68
219
953
652
4257
1.84
30.66
8.4
3.5
33.90
32.81
u/l
0.31
629
4049
321
1649
2.15
30.33
12.8
6.9
5.25
4.96
kpa
1.70
316
1599
238
1085
2.37
30.00
10.2
9.9
95.88
95.42
%
0.38
232
1043
371
2026
2.04
29.74
4.4
2.7
12.16
13.57
umol/l
3.54
363
1897
483
2898
1.91
29.43
5.8
3.6
1.02
1.02
kg/l
0.02
49
462
125
418
3.12
28.91
9.1
5.1
—
—
—
0
0
834
5938
1.76
28.72
5.4
4.1
—
—
—
0
0
179
730
2.60
28.63
10.9
6.3
123.18
128.90
g/l
2.49
174
716
176
713
2.62
28.53
11.4
11.6
1.32
1.28
%
0.22
176
707
175
707
2.62
28.52
11.5
11.9
94.53
94.22
%
0.32
175
702
253
1211
2.26
28.38
9.7
9.3
0.30
0.95
mmol/l
1.71
197
956
175
712
2.60
28.11
11.4
11.7
0.73
0.68
%
0.88
175
707
117
384
3.17
27.92
2.7
3.3
283.41
3695.75
u/ml
0.72
102
330
512
3178
1.85
27.80
4.2
2.5
—
—
—
0
0
363
2013
2.00
27.67
12.1
6.2
0.80
0.81
mmol/l
1.20
346
1904
124
424
3.05
27.60
2.6
1.7
—
11.52
—
0
6
36
44
8.28
27.20
5.6
2.5
—
—
—
0
0
119
407
3.05
26.46
2.6
1.8
112.88
101.93
u/ml
0.49
17
52
248
1210
2.21
26.45
9.8
9.3
5.04
5.17
kpa
1.53
241
1159
247
1210
2.20
26.06
9.8
9.3
13.29
12.85
kpa
0.50
239
1162
121
428
2.94
25.35
2.6
1.8
—
—
—
0
0
583
3849
1.76
25.30
5.5
3.4
0.22
0.39
e6/l
2.42
486
2893
578
3808
1.76
25.26
5.5
3.4
—
—
—
0
0
332
1851
1.97
24.65
4.5
2.7
2.43
2.41
g/l
0.26
323
1736
204
948
2.29
24.39
3.5
4.1
3.90
27.01
ug/l
1.79
153
768
314
1725
1.99
24.30
4.7
2.8
19.79
22.93
%
4.36
289
1529
582
3881
1.74
24.14
9.6
7.7
—
—
—
0
0
554
3651
1.75
23.92
3.7
2.7
—
—
—
0
0
265
1378
2.08
23.85
14.2
7.5
23.77
23.74
mmol/l
0.09
252
1307
753
5417
1.67
23.38
4.4
2.6
75.45
73.67
nmol/l
1.08
713
4952
611
4164
1.71
23.22
5.7
3.6
40.91
71.50
e6/l
0.81
517
3189
96
313
3.17
23.15
10.4
2.9
25.37
6.88
umol/l
3.41
89
251
979
7577
1.65
22.52
11.0
7.6
0.20
0.20
e9/l
0.05
877
6580
986
7652
1.65
22.38
10.6
5.6
6.37
6.45
mmol/l
0.63
935
7114
977
7572
1.65
22.23
10.4
7.1
2.10
2.08
e9/l
0.11
871
6606
310
1745
1.93
22.18
2.4
2.0
—
—
—
0
0
1093
8725
1.66
22.04
6.2
4.2
2782.93
1297.04
e6/l
0.30
18
114
953
7351
1.64
22.00
10.5
7.1
0.04
0.04
e9/l
0.32
845
6275
42
77
5.53
21.81
1.0
1.0
—
—
—
0
0
853
6414
1.63
21.71
5.4
3.5
0.00
0.00
estimate
0.00
120
1217
949
7335
1.63
21.54
10.5
7.1
0.57
0.57
e9/l
0.08
843
6251
852
6434
1.62
21.08
6.9
4.8
0.00
0.00
estimate
0.50
123
1251
41
76
5.47
21.05
1.0
1.2
—
—
—
0
0
183
874
2.21
20.37
2.8
2.4
6.47
7.37
ug/l
0.25
164
770
854
6494
1.60
20.23
5.4
3.5
0.02
0.00
estimate
0.30
123
1211
227
1182
2.05
20.18
4.2
2.4
40.96
74.92
u/l
0.38
204
982
101
367
2.84
20.14
1.8
1.4
64.00
75.64
titre
—
10
39
516
3466
1.68
20.11
3.7
2.4
2.98
2.84
mg/l
0.80
467
3004
69
200
3.53
20.07
2.5
2.5
—
—
—
0
0
681
4919
1.62
19.86
6.7
4.1
39.78
80.37
e6/l
2.43
547
3407
576
3996
1.65
19.74
3.6
3.3
2.37
2.36
mmol/l
0.77
532
3536
66
190
3.55
19.40
1.3
1.3
—
—
—
0
0
140
611
2.39
19.24
8.4
7.4
23.88
24.46
mmol/l
1.01
133
569
283
1617
1.88
19.15
20.8
11.7
24.87
24.60
mmol/l
0.85
283
1610
145
655
2.31
18.42
8.7
4.6
22.74
22.66
s
0.06
137
607
142
638
2.32
18.26
5.7
5.2
—
—
—
0
0
80
271
3.03
18.10
14.8
9.7
74.14
64.94
%
3.52
80
271
97
367
2.72
17.93
5.5
4.1
1.31
1.41
mmol/l
0.42
97
358
360
2271
1.73
17.35
4.6
3.2
2.81
2.45
e6/l
0.27
234
1252
98
380
2.66
17.27
7.5
3.2
39.54
33.25
umol/l
1.39
89
334
285
1684
1.82
17.20
2.0
1.7
—
—
—
0
0
629
4578
1.57
17.10
2.3
2.0
—
—
—
0
0
119
512
2.41
16.87
2.2
1.6
224.05
206.56
u/ml
0.33
81
264
416
2753
1.66
16.68
4.5
2.4
1.68
1.27
mg/l
0.82
303
2048
1424
12526
1.73
16.57
30.7
16.1
333.04
333.69
g/l
1.81
1413
12421
419
2784
1.65
16.52
4.5
3.0
326.89
5375.44
umol/l
8.24
371
2447
494
3423
1.61
16.43
6.1
3.8
0.00
0.00
estimate
1.08
122
1203
411
2721
1.66
16.42
4.3
2.9
532.44
569.87
mosm/kgh2o
2.32
359
2342
1039
8493
1.54
16.39
8.3
3.2
59.09
41.70
u/l
5.30
986
8003
38
83
4.63
16.22
3.2
1.6
0.89
1.00
g/l
0.96
38
83
155
761
2.12
16.03
1.5
1.2
—
—
—
0
0
1536
13878
1.88
15.46
24.1
12.6
24.42
23.36
mg/l
0.61
1284
10458
482
3363
1.59
15.40
2.5
2.3
180.56
277.94
u/l
1.84
452
3183
1143
9609
1.53
15.28
5.7
4.1
11.15
10.42
mm/h
1.10
1094
8891
83
315
2.70
15.27
14.6
9.2
—
—
—
0
0
1093
9136
1.51
14.71
6.1
4.2
—
—
—
0
0
309
1948
1.70
14.71
2.8
2.8
2.45
2.44
mmol/l
0.51
273
1698
1496
13476
1.76
14.30
27.9
14.6
3.96
3.96
mmol/l
0.60
1464
13050
1493
13444
1.75
14.26
28.0
14.5
139.36
139.57
mmol/l
2.96
1462
13060
259
1582
1.74
13.77
5.7
4.2
1.62
1.65
%
0.22
239
1451
604
4542
1.49
13.30
2.1
1.9
94.56
95.63
pmol/l
0.23
338
2397
29
60
4.87
13.21
1.1
1.3
—
—
—
0
0
429
3005
1.56
13.16
6.9
4.7
—
—
—
0
0
124
603
2.12
13.13
12.8
12.9
—
—
—
0
0
297
1909
1.66
13.02
1.9
1.6
—
—
—
0
0
800
6396
1.45
12.69
4.4
2.9
91.57
99.17
ug/l
0.72
770
5967
674
5220
1.46
12.62
10.9
7.5
—
—
—
0
0
1537
14066
1.76
12.40
17.2
9.6
28.26
26.26
u/l
1.89
1502
13583
72
286
2.57
12.14
1.8
1.7
—
—
—
0
0
206
1222
1.77
12.07
26.6
22.2
1.45
1.26
inr
0.52
23
178
198
1163
1.78
12.00
4.7
3.5
68.80
68.78
e9/l
0.00
146
821
115
567
2.09
11.76
6.1
5.3
0.26
0.28
g/l
0.12
85
327
236
1469
1.69
11.62
1.6
1.5
—
—
—
0
0
317
2128
1.59
11.55
3.7
2.7
146.43
117.68
ug/g
0.53
268
1692
19
30
6.35
11.46
1.6
2.2
—
—
—
0
0
60
224
2.72
11.45
5.2
1.9
70.39
72.43
mmol/l
0.12
54
190
1534
14094
1.71
11.37
24.1
13.8
76.33
71.79
umol/l
2.60
1534
14087
26
56
4.67
11.32
7.3
7.7
1.69
2.46
mg/l
0.95
20
44
854
7037
1.41
10.81
11.3
7.4
8.28
8.44
%
0.87
824
6653
110
554
2.04
10.64
2.6
2.4
—
—
—
0
0
1549
14327
1.70
10.44
19.3
11.2
—
—
—
0
0
827
6803
1.40
10.44
10.9
7.3
0.61
0.65
%
1.80
796
6425
878
7296
1.40
10.44
10.8
7.2
30.28
30.89
%
0.73
846
6887
865
7175
1.40
10.37
10.6
7.0
55.04
54.11
%
1.23
834
6802
846
6993
1.39
10.34
11.0
7.2
2.90
2.99
%
0.42
814
6581
38
116
3.31
10.31
1.7
2.0
—
—
—
0
0
45
153
2.97
10.22
11.1
15.4
11.07
11.32
%
0.18
45
153
91
437
2.13
9.99
1.4
1.2
—
—
—
0
0
38
122
3.14
9.52
4.3
3.8
—
—
—
0
0
944
8011
1.38
9.50
4.4
3.4
—
—
—
0
0
523
4030
1.41
9.42
3.9
3.4
36.14
45.57
ng/l
0.24
329
2533
86
415
2.11
9.34
3.9
3.2
—
—
—
0
0
20
41
4.89
9.23
1.9
2.3
1009.21
746.38
e6/l
0.36
14
34
17
31
5.49
8.90
1.6
2.0
—
—
—
0
0
500
3856
1.41
8.87
4.4
3.5
7.06
7.94
mmol/l
3.95
458
3323
196
1245
1.64
8.86
2.5
3.3
10.09
9.89
g/l
0.28
188
1152
217
1415
1.60
8.82
2.9
2.3
323.47
359.02
nmol/l
2.04
202
1323
208
1344
1.61
8.78
16.4
7.7
—
—
—
0
0
36
118
3.07
8.74
4.0
2.1
23.44
20.52
umol/l
0.23
36
113
224
1478
1.58
8.66
1.3
1.3
—
—
—
0
0
153
923
1.71
8.42
2.0
1.5
—
—
—
0
0
29
86
3.39
8.27
2.7
2.1
—
—
—
0
0
146
874
1.72
8.26
3.5
3.8
208.50
196.60
ng/l
0.13
132
794
800
6730
1.34
7.95
14.0
9.8
0.00
0.00
e9/l
0.54
655
5371
1345
12248
1.41
7.88
28.0
15.8
13.67
13.46
%
6.31
1321
12010
353
2610
1.43
7.82
1.6
1.5
21.35
20.44
nmol/l
0.55
326
2238
17
35
4.86
7.82
1.9
2.0
5861.00
3963.23
e6/l
—
10
22
27
80
3.39
7.72
1.0
1.0
—
—
—
0
0
304
2192
1.46
7.69
4.4
3.6
587.20
524.23
ng/l
0.13
218
1537
193
1268
1.58
7.58
1.5
1.3
—
—
—
0
0
93
499
1.90
7.56
2.1
1.9
1.40
1.43
g/l
0.10
85
439
181
1175
1.59
7.48
18.6
8.5
9.84
9.43
kpa
2.27
170
1127
363
2721
1.41
7.41
1.9
1.7
—
—
—
0
0
27
83
3.27
7.31
1.0
1.1
—
—
—
0
0
268
1904
1.47
7.30
1.8
1.7
1285.28
1180.97
nmol/l
1.17
211
1431
79
408
1.97
7.20
2.5
1.9
1.50
2.12
ug/l
0.33
72
362
64
306
2.12
7.18
6.2
7.0
1.22
1.29
mmol/l
0.29
53
265
382
2905
1.39
7.14
4.1
3.7
1308.47
1300.13
ng/l
0.01
337
2453
74
375
2.00
7.12
1.6
1.4
271.60
321.44
ug/g
1.23
50
217
256
1821
1.47
6.91
1.6
1.4
548.09
518.14
titre
0.07
47
344
157
1004
1.61
6.91
2.0
1.4
—
—
—
0
0
232
1623
1.49
6.81
17.3
7.5
7.39
7.40
ph
0.97
12
108
233
1633
1.48
6.78
17.4
7.4
5.10
5.07
kpa
0.26
220
1557
1293
11799
1.35
6.70
4.9
3.9
4.43
4.59
mmol/l
7.73
1228
11018
1239
11235
1.34
6.70
4.5
3.5
1.22
1.24
mmol/l
0.54
1170
10404
57
268
2.15
6.70
1.2
1.2
—
—
—
0
0
1184
10669
1.32
6.67
6.4
5.1
38.51
38.76
mmol/mol
0.40
1127
9954
10
14
7.13
6.65
9.2
4.2
5.69
7.36
mmol/l
—
10
14
40
162
2.49
6.61
4.6
3.6
—
—
—
0
0
1164
10499
1.31
6.30
4.2
3.7
14.94
14.66
pmol/l
3.35
1095
9550
10
15
6.66
6.26
1.4
1.8
113.71
97.07
ng/l
—
10
15
135
855
1.62
6.20
2.7
3.1
65.23
66.37
g/l
0.94
125
786
1300
11922
1.33
6.16
5.2
4.2
2.61
2.74
mmol/l
6.98
1224
11053
52
249
2.11
5.87
2.4
2.5
67.32
136.56
ug/min
0.65
29
149
11
20
5.49
5.76
1.5
4.0
—
—
—
0
0
1436
13411
1.37
5.72
25.5
14.2
39.16
39.80
%
2.67
1097
10556
130
835
1.59
5.65
1.5
1.5
—
—
—
0
0
1638
15705
1.67
5.53
33.7
18.4
6.90
6.77
e9/l
1.48
1595
15166
1637
15694
1.66
5.52
33.5
18.4
89.17
89.25
fl
0.26
1617
15473
51
249
2.07
5.49
2.2
1.8
—
—
—
0
0
51
249
2.07
5.49
2.2
1.8
—
—
—
0
0
51
249
2.07
5.49
2.2
1.8
—
—
—
0
0
51
249
2.07
5.49
2.2
1.8
—
—
—
0
0
1637
15696
1.66
5.49
33.5
18.3
29.77
29.84
pg
0.83
1617
15476
1637
15698
1.66
5.46
33.7
18.4
4.51
4.55
e12/l
2.93
1593
15157
1272
11700
1.30
5.43
4.7
3.9
1.42
1.44
mmol/l
1.52
1200
10860
1637
15706
1.65
5.34
34.1
18.6
133.30
135.19
g/l
5.81
1619
15484
1635
15684
1.64
5.32
33.7
18.5
255.53
256.81
e9/l
0.32
1592
15182
166
1164
1.46
4.82
1.4
1.4
192.15
254.94
u/ml
0.75
156
1082
27
108
2.51
4.65
1.6
1.2
—
—
—
0
0
387
3131
1.29
4.57
1.9
1.7
1.28
1.37
mmol/l
1.18
358
2699
366
2942
1.30
4.54
4.0
3.3
557.50
252.13
mg/l
0.51
280
1940
118
786
1.53
4.42
2.7
3.3
4.71
4.76
pmol/l
0.17
105
709
344
4184
0.77
4.41
2.7
2.5
—
—
—
0
0
423
3478
1.28
4.38
2.2
2.0
—
—
—
0
0
22
84
2.62
4.18
2.8
3.7
20.07
20.32
mmol/l
0.01
22
79
1245
11555
1.25
4.17
4.7
3.9
5.77
5.78
mmol/l
0.07
1171
10570
18
62
2.90
4.12
2.1
2.7
—
—
—
0
0
40
201
2.00
4.07
3.7
4.1
0.47
1.02
%
2.21
31
170
15
48
3.12
3.89
12.2
5.6
—
—
—
0
0
40
205
1.96
3.86
3.1
3.4
11.97
9.96
%
0.57
29
170
374
3086
1.26
3.71
4.6
4.1
46.79
9.71
mg/mmol
0.46
281
2004
65
396
1.66
3.59
11.5
6.1
23.46
24.24
mmol/l
0.93
60
355
75
475
1.59
3.55
1.1
1.2
—
—
—
0
0
7
9
7.75
3.54
3.0
2.7
—
—
—
0
0
31
150
2.07
3.52
1.1
1.1
—
—
—
0
0
22
92
2.39
3.51
1.8
2.2
—
—
—
0
0
43
234
1.85
3.51
1.0
1.1
—
—
—
0
0
18
69
2.61
3.43
6.9
3.1
3.44
3.37
%
—
7
28
22
94
2.34
3.36
1.6
2.7
40.43
40.49
%
—
7
29
42
231
1.83
3.33
3.0
3.3
1.61
1.48
e9/l
0.31
33
146
1303
12261
1.23
3.29
5.0
4.4
1.91
2.11
mu/l
0.83
1234
11334
18
71
2.53
3.25
1.1
1.1
—
—
—
0
0
39
212
1.85
3.21
9.2
4.8
—
—
—
0
0
23
104
2.21
3.11
1.6
1.2
—
—
—
0
0
62
390
1.60
3.06
7.2
6.1
0.86
0.89
%
0.27
56
364
43
245
1.76
3.06
1.0
1.1
—
—
—
0
0
12
39
3.07
3.05
3.3
3.1
25.66
25.73
mg/l
—
5
15
38
209
1.82
3.04
8.7
8.4
105.27
105.34
mmol/l
0.03
33
186
38
209
1.82
3.04
8.7
8.4
10.52
11.42
mmol/l
0.90
33
186
275
2241
1.26
3.01
1.7
1.6
472.79
26075845.57
pmol/l
1.97
240
1883
29
146
1.99
3.00
1.1
1.1
—
—
—
0
0
61
392
1.57
2.78
6.9
6.1
1.74
1.54
%
0.51
55
364
36
201
1.80
2.77
3.7
4.6
—
—
—
0
0
49
299
1.65
2.76
3.3
2.5
131.02
131.51
g/l
0.05
41
233
5
6
8.30
2.74
1.0
1.0
40.74
34.52
s
—
5
6
50
308
1.63
2.72
1.3
1.2
—
—
—
0
0
12
42
2.85
2.72
2.0
1.9
—
—
—
0
0
31
168
1.85
2.63
3.6
3.6
302.73
365.83
e6/l
0.41
22
108
45
273
1.65
2.61
11.5
4.7
2.64
2.31
mmol/l
0.33
30
163
78
539
1.46
2.56
1.2
1.5
—
9.69
—
0
17
36
207
1.74
2.53
3.1
3.3
0.26
0.19
e9/l
0.99
30
157
479
4198
1.18
2.53
1.6
1.6
—
—
—
0
0
24
121
1.98
2.51
1.1
1.1
—
—
—
0
0
13
50
2.60
2.50
2.7
2.4
25.01
16.72
umol/l
1.18
13
50
7
16
4.36
2.46
2.0
3.0
16695.00
4662.88
u/l
—
7
16
21
103
2.04
2.38
6.0
3.5
59.00
141.60
umol/l
—
6
33
7
17
4.10
2.34
1.3
1.4
—
—
—
0
0
135
1041
1.31
2.31
5.2
4.6
0.86
0.86
%
0.00
55
310
16
71
2.25
2.31
1.6
1.5
—
2119.08
—
0
12
152
1193
1.29
2.29
1.6
1.4
—
—
—
0
0
41
255
1.61
2.20
1.6
1.7
12020.32
15488.96
e6/l
0.30
25
199
460
4061
1.17
2.19
1.5
1.5
3.52
2.38
u/ml
0.52
115
921
102
1326
0.75
2.14
1.2
1.3
—
—
—
0
0
7
19
3.67
2.13
20.9
9.8
—
—
—
0
0
420
3689
1.17
2.13
1.6
1.6
2.02
2.03
g/l
0.04
269
2104
20
101
1.98
2.12
1.2
1.4
31414.69
49331.85
e6/l
0.24
13
71
31
181
1.71
2.11
1.9
1.7
284.29
286.32
mosm/kgh2o
0.22
24
128
42
266
1.58
2.10
1.8
1.6
0.77
0.79
g/l
0.05
35
214
44
282
1.56
2.10
8.8
4.6
—
—
—
0
0
10
37
2.70
2.08
2.0
2.6
—
—
—
0
0
156
1247
1.27
2.05
1.5
1.4
—
—
—
0
0
33
201
1.64
1.95
3.0
2.1
1.55
1.71
mmol/l
0.54
33
195
74
536
1.39
1.94
1.4
1.2
—
—
—
0
0
34
209
1.63
1.94
3.2
3.3
607.64
532.78
e6/l
0.34
28
156
51
349
1.47
1.83
1.4
1.2
—
—
—
0
0
13
59
2.20
1.81
3.4
3.6
174.52
123.28
ug/l
0.39
13
59
40
263
1.52
1.75
4.5
2.8
16.71
16.84
%
0.08
25
146
42
280
1.50
1.73
3.6
3.6
3.59
3.91
e9/l
0.48
42
280
83
630
1.32
1.66
2.1
2.5
—
—
—
0
0
43
291
1.48
1.66
4.3
3.9
53.56
55.12
%
0.32
43
291
352
3109
1.16
1.65
3.4
3.5
—
—
—
0
0
108
851
1.28
1.64
2.5
2.4
7379.76
4918.56
u/l
0.16
41
319
7
25
2.79
1.63
11.0
3.4
38.29
41.68
umol/l
—
7
19
76
572
1.33
1.61
1.1
1.3
169.47
241.11
miu/ml
1.35
36
271
12
56
2.14
1.58
1.7
1.8
20.40
18.41
nmol/l
—
5
17
7
26
2.68
1.57
1.1
1.4
—
—
—
0
0
88
682
1.30
1.53
1.7
1.9
7.91
7.57
u/l
0.10
70
477
14
71
1.97
1.51
1.1
1.1
1753.07
1726.28
miu/ml
0.03
14
71
102
808
1.27
1.51
1.2
1.2
—
—
—
0
0
31
202
1.53
1.45
1.3
1.2
—
—
—
0
0
7
28
2.49
1.44
3.4
3.0
—
—
—
0
0
29
187
1.55
1.42
1.1
1.2
—
—
—
0
0
9
39
2.30
1.42
2.4
7.4
—
—
—
0
0
325
2888
1.15
1.41
4.5
4.8
2.26
2.75
ug/l
0.63
297
2585
14
74
1.89
1.36
1.3
1.4
—
—
—
0
0
9
41
2.19
1.36
1.2
1.6
—
—
—
0
0
19
112
1.69
1.32
5.7
3.6
56.00
54.78
%
0.06
11
78
10
47
2.12
1.31
1.9
3.4
—
—
—
0
0
46
332
1.39
1.31
1.2
1.2
15.42
11.08
u/ml
—
6
50
126
1041
1.22
1.31
2.3
2.2
10.89
12.12
nmol/l
0.81
109
891
59
445
1.33
1.28
1.3
1.2
3.52
1.05
u/ml
—
9
31
8
34
2.34
1.28
1.3
1.1
—
—
—
0
0
115
946
1.22
1.26
5.5
4.7
0.03
0.44
%
0.61
38
246
8
36
2.21
1.23
1.1
1.8
—
—
—
0
0
48
354
1.36
1.22
1.1
1.1
8.06
8.87
u/ml
0.10
30
189
116
960
1.21
1.20
4.8
4.3
0.55
0.54
%
0.01
31
230
31
212
1.46
1.20
1.6
1.2
10.17
6.15
u/ml
0.52
18
94
95
771
1.24
1.19
1.7
1.7
20.21
17.45
iu/l
0.34
80
577
28
403
0.69
1.19
1.5
1.5
—
—
—
0
0
64
495
1.30
1.19
1.3
1.5
1.17
1.17
g/l
0.04
59
472
8
38
2.10
1.17
1.1
1.2
—
—
—
0
0
20
125
1.60
1.15
1.6
4.7
—
—
—
0
0
62
480
1.29
1.15
1.4
1.5
0.22
0.22
g/l
0.06
57
462
11
57
1.92
1.15
1.2
1.3
154.00
140.52
nmol/l
0.41
11
57
119
994
1.20
1.14
5.4
4.7
0.15
0.12
%
0.14
46
285
129
1087
1.19
1.12
1.2
1.2
139.70
136.42
iu/ml
0.03
53
397
60
466
1.29
1.10
1.8
1.7
—
—
—
0
0
46
345
1.33
1.08
2.0
2.1
0.93
0.67
nmol/l
0.56
41
293
219
1934
1.14
1.07
1.3
1.2
28.96
10.58
u/ml
0.42
79
715
28
393
0.70
1.06
1.5
1.4
—
—
—
0
0
28
393
0.70
1.06
1.5
1.4
—
—
—
0
0
5
22
2.26
1.02
1.2
1.2
—
—
—
0
0
11
60
1.83
1.01
2.1
1.8
—
—
—
0
0
58
456
1.27
0.99
1.1
1.1
—
—
—
0
0
7
133
0.52
0.98
1.6
1.6
—
—
—
0
0
22
147
1.49
0.98
4.3
2.9
21.00
18.53
ug/l
0.59
22
147
21
139
1.51
0.97
3.3
2.4
—
—
—
0
0
45
344
1.31
0.95
20.0
9.2
—
—
—
0
0
26
183
1.42
0.91
1.3
1.4
—
—
—
0
0
49
383
1.28
0.89
1.1
1.1
6.88
6.90
u/ml
0.00
30
194
67
809
0.82
0.89
1.3
1.3
—
—
—
0
0
18
118
1.52
0.88
1.1
1.0
—
—
—
0
0
71
581
1.22
0.88
1.2
1.2
3.95
6.50
u/ml
1.49
38
394
19
274
0.69
0.87
1.2
1.1
5.03
4.22
u/ml
—
9
101
14
87
1.60
0.85
1.6
1.4
—
—
—
0
0
6
31
1.93
0.84
1.0
1.1
—
—
—
0
0
107
916
1.17
0.83
9.1
4.0
1.23
1.23
mmol/l
0.40
96
797
75
624
1.20
0.80
1.2
1.2
3.34
2.78
u/ml
0.10
43
366
27
197
1.37
0.79
1.4
1.4
21.72
16.92
u/l
0.40
20
168
25
180
1.39
0.79
1.5
1.3
—
—
—
0
0
0
24
0.00
0.79
0.0
2.0
—
—
—
0
0
226
2046
1.11
0.77
1.3
1.2
47.68
28.24
iu/ml
0.68
61
586
35
268
1.30
0.76
8.5
5.0
—
—
—
0
0
14
90
1.55
0.76
1.2
1.4
—
—
—
0
0
13
82
1.58
0.76
1.9
3.0
911.31
1110.24
u/ml
0.28
13
82
5
23
2.16
0.76
1.2
1.4
—
—
—
0
0
6
34
1.76
0.75
9.2
16.0
—
—
—
0
0
48
384
1.25
0.75
2.8
2.8
1585.11
742.28
e6/l
0.35
38
300
48
384
1.25
0.75
2.8
2.8
15.11
17.67
e6/l
0.06
36
290
28
208
1.34
0.75
1.3
1.6
—
—
—
0
0
42
331
1.27
0.74
1.1
1.1
—
—
—
0
0
52
421
1.23
0.74
2.5
2.7
414.15
438.21
mg/l
0.16
52
404
7
38
1.83
0.73
3.4
2.4
—
—
—
0
0
26
192
1.35
0.72
1.2
1.6
—
—
—
0
0
100
864
1.16
0.71
2.8
2.7
4.00
4.10
e9/l
0.15
82
708
68
569
1.20
0.71
1.1
1.2
0.65
1.37
u/ml
1.16
33
359
45
361
1.24
0.70
2.8
2.9
—
—
—
0
0
27
202
1.33
0.70
1.1
1.2
—
—
—
0
0
24
177
1.35
0.68
1.5
1.3
6.90
6.36
g/l
0.31
18
138
24
177
1.35
0.68
1.5
1.3
0.46
0.37
g/l
0.68
18
136
24
177
1.35
0.68
1.5
1.3
2.56
2.36
g/l
0.30
18
138
16
110
1.45
0.66
1.3
1.3
813.00
2486.33
e6/l
2.27
11
73
15
102
1.47
0.65
1.5
1.4
—
—
—
0
0
41
330
1.24
0.63
1.0
1.1
1.51
0.41
u/ml
0.36
18
132
172
1558
1.11
0.61
1.2
1.2
—
—
—
0
0
18
243
0.73
0.61
1.4
1.2
—
—
—
0
0
8
50
1.59
0.61
1.1
1.7
—
—
—
0
0
15
104
1.44
0.60
1.3
1.3
4867.22
41779.52
e6/l
—
9
60
20
147
1.36
0.59
2.4
2.1
32.25
32.55
pg
0.10
20
147
22
165
1.33
0.58
1.6
1.5
—
—
—
0
0
39
317
1.23
0.57
1.5
2.5
9.87
10.46
g/l
0.45
33
272
16
114
1.40
0.57
1.5
1.1
—
—
—
0
0
13
89
1.45
0.56
2.2
1.5
7.34
6.21
ug/l
0.41
13
77
105
931
1.13
0.55
2.4
2.3
14.23
18.29
au/ml
—
7
55
25
193
1.29
0.55
1.5
1.6
—
—
—
0
0
10
65
1.53
0.54
1.3
1.3
—
87.33
%
—
0
6
64
550
1.16
0.53
3.1
1.7
—
—
—
0
0
42
351
1.19
0.49
1.8
1.9
7.19
5.43
iu/l
0.25
16
120
18
137
1.31
0.45
1.4
1.3
—
—
—
0
0
11
152
0.72
0.45
1.5
1.4
—
—
—
0
0
101
1105
0.90
0.44
2.0
1.9
—
—
—
0
0
60
677
0.88
0.43
1.4
1.6
—
—
—
0
0
34
284
1.19
0.41
1.1
1.2
190.20
199.34
iu/ml
—
5
83
0
16
0.00
0.41
0.0
5.5
—
—
—
0
0
0
16
0.00
0.41
0.0
3.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
5
33
1.51
0.41
1.2
1.3
—
—
—
0
0
8
59
1.35
0.40
1.1
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
58
508
1.14
0.40
2.3
2.6
—
—
—
0
0
26
212
1.22
0.40
3.2
3.9
—
—
—
0
0
5
34
1.46
0.40
3.6
1.3
—
—
—
0
0
77
691
1.11
0.37
1.5
1.6
305.99
311.12
mu/l
0.06
70
622
14
179
0.78
0.37
1.1
1.2
—
—
—
0
0
17
134
1.26
0.35
1.5
1.2
—
—
nmol/l
—
0
0
6
42
1.42
0.35
2.2
1.4
—
—
—
0
0
12
90
1.33
0.34
1.1
1.1
—
—
—
0
0
52
459
1.13
0.34
1.2
1.3
—
—
—
0
0
15
117
1.28
0.34
1.8
1.4
1.38
1.31
promille
—
10
94
72
787
0.91
0.33
3.2
2.6
—
—
—
0
0
13
165
0.78
0.33
1.6
1.6
—
—
—
0
0
6
46
1.30
0.33
1.2
1.2
—
—
—
0
0
21
172
1.22
0.32
1.6
1.9
—
—
—
0
0
13
100
1.29
0.32
1.4
1.5
—
—
—
0
0
105
1123
0.92
0.31
2.0
2.0
—
—
—
0
0
7
53
1.31
0.30
1.9
2.1
3.09
3.66
ug/l
—
7
47
7
53
1.31
0.30
1.9
2.1
1.86
2.19
ug/l
—
7
43
105
1120
0.93
0.30
2.0
2.0
—
—
—
0
0
11
84
1.30
0.29
1.5
2.0
—
1.69
—
0
6
27
231
1.16
0.28
4.1
3.8
—
—
—
0
0
28
241
1.16
0.27
1.2
1.5
1.64
4.38
u/ml
1.15
20
156
38
335
1.13
0.27
1.1
1.1
—
—
—
0
0
11
85
1.29
0.27
1.1
1.1
347.45
392.01
nmol/l
0.25
11
76
5
73
0.68
0.26
1.0
1.0
—
7.40
—
0
7
105
1111
0.94
0.25
2.0
2.0
—
—
—
0
0
14
113
1.23
0.25
1.0
1.0
—
—
—
0
0
38
337
1.12
0.25
1.1
1.1
—
—
—
0
0
9
73
1.23
0.25
1.1
1.1
—
—
—
0
0
9
76
1.18
0.24
1.3
1.2
—
—
—
0
0
5
41
1.21
0.22
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
5
42
1.18
0.21
1.0
1.3
371.00
72.16
mu/l
—
5
35
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
44
399
1.10
0.21
1.5
1.8
40.43
39.27
nmol/l
0.13
44
386
62
572
1.08
0.21
3.7
3.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
0.19
—
0
6
28
248
1.12
0.20
1.2
1.1
—
—
—
0
0
6
51
1.17
0.19
1.0
1.5
—
—
—
0
0
41
373
1.09
0.19
2.6
2.6
—
—
—
0
0
7
61
1.14
0.17
1.1
1.6
1.00
1.13
nmol/l
—
7
46
140
1338
1.04
0.17
1.9
1.8
—
—
—
0
0
100
1041
0.95
0.16
2.0
2.0
—
—
—
0
0
6
76
0.78
0.15
1.0
1.2
—
—
—
0
0
12
101
1.18
0.15
1.2
1.1
—
—
—
0
0
6
77
0.77
0.15
1.0
1.1
—
—
—
0
0
12
139
0.86
0.15
1.1
1.1
—
—
—
0
0
24
263
0.91
0.14
1.0
1.0
20.25
19.36
mmol/l
0.76
24
257
15
130
1.15
0.14
1.4
1.3
—
—
—
0
0
111
1147
0.96
0.14
5.8
3.8
—
—
—
0
0
19
168
1.13
0.14
1.6
1.5
—
—
—
0
0
7
90
0.77
0.14
1.0
1.2
—
2.90
—
0
18
112
1071
1.04
0.14
7.4
4.2
—
—
—
0
0
11
127
0.86
0.13
2.7
3.6
—
—
—
0
0
17
150
1.13
0.13
1.6
1.2
—
—
—
0
0
18
160
1.12
0.13
1.6
1.2
0.44
0.56
nmol/l
2.53
18
152
85
880
0.96
0.12
2.1
2.1
—
—
—
0
0
12
136
0.88
0.12
1.8
1.8
—
—
—
0
0
16
142
1.12
0.11
1.1
1.4
39.50
15.79
u/ml
0.32
11
116
244
2376
1.02
0.11
1.6
1.6
—
—
—
0
0
18
197
0.91
0.11
2.8
1.4
—
—
—
0
0
23
210
1.09
0.11
2.4
2.9
—
—
—
0
0
24
258
0.92
0.10
1.0
1.0
-0.70
-2.56
mmol/l
—
7
60
24
258
0.92
0.10
1.0
1.0
—
—
—
0
0
26
278
0.93
0.10
4.7
3.4
23.77
24.92
mg/l
0.08
19
171
5
43
1.16
0.10
1.4
3.2
—
—
—
0
0
5
45
1.10
0.09
1.0
1.3
—
—
—
0
0
6
53
1.13
0.09
2.3
2.5
—
258.19
—
0
6
11
123
0.89
0.09
1.0
1.0
152.82
165.38
g/l
0.90
11
123
6
54
1.10
0.09
1.3
1.5
—
—
—
0
0
6
56
1.06
0.08
1.0
1.0
—
—
—
0
0
164
1663
0.98
0.08
2.6
3.0
0.67
0.77
ug/l
0.68
118
1069
6
57
1.05
0.08
2.0
3.2
—
—
—
0
0
6
58
1.03
0.08
1.0
1.0
—
13.66
—
0
10
58
598
0.96
0.08
1.1
1.1
—
—
—
0
0
6
70
0.85
0.07
4.2
2.4
494.17
513.32
min
—
6
53
347
3487
0.99
0.07
4.0
3.2
—
—
—
0
0
18
193
0.93
0.07
1.2
1.2
1.05
2.41
u/ml
—
7
49
16
146
1.09
0.07
1.2
1.2
—
—
—
0
0
9
86
1.04
0.07
1.3
1.2
—
—
—
0
0
29
303
0.95
0.06
3.9
2.0
—
—
—
0
0
77
746
1.03
0.06
2.2
2.8
—
—
—
0
0
17
158
1.07
0.05
1.5
1.8
—
—
—
0
0
213
2093
1.01
0.05
1.9
1.8
—
—
—
0
0
27
257
1.04
0.04
2.7
4.1
—
—
—
0
0
11
118
0.93
0.03
1.5
2.2
—
—
—
0
0
14
131
1.06
0.02
1.4
1.4
0.07
0.96
u/ml
—
5
45
10
92
1.08
0.02
1.2
1.2
—
—
—
0
0
12
112
1.06
0.02
1.2
1.2
—
—
—
0
0
57
558
1.02
0.01
1.2
1.2
5.06
3.47
u/ml
0.27
23
178
12
121
0.99
0.00
2.3
2.5
—
—
—
0
0
11
105
1.04
0.00
1.5
2.2
6.05
6.22
mmol/l
—
6
78
25
246
1.01
0.00
1.3
1.4
19.68
10.50
u/ml
0.21
15
146
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.01
0.00
1.6
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
17.38
—
0
9
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
5
50
0.99
0.00
1.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
8
86
0.92
0.00
2.3
1.4
35.64
34.75
nmol/l
—
8
74
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.01
0.00
1.7
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
5
57
0.87
0.00
1.0
1.5
—
—
—
0
0
5
49
1.01
0.00
1.6
1.1
—
—
—
0
0
5
49
1.01
0.00
1.6
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
403.33
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
24.24
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
188.80
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1 and mortality.

Females

Parameter HR [95% CI] p-value
Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1 1.416 [1.22, 1.64] < 0.001
Birth year 0.995 [0.99, 1.0] 0.253

During the follow-up period (1.1.1998 — 31.12.2019), 639 out of 10892 females with Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1 died.

Males

Parameter HR [95% CI] p-value
Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1 1.635 [1.36, 1.97] < 0.001
Birth year 0.985 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 708 out of 19100 males with Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1 died.

Mortality risk

Mortality risk for people of age

years, who have Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1.

N-year risk Females Males
1 0.119% 0.326%
5 0.74% 1.886%
10 1.92% 4.408%
15 3.899% 8.147%
20 7.066% 13.474%

Relationships between endpoints

Index endpoint: Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1 – Other congenital malformations of the digestive system

GWS hits: 6

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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