Cystic disease of liver

Q17_CYSTIC_DISEASE_OF_LIVER

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q44.6
  • Cause of death: ICD-10 Q44.6

2 out of 7 registries used, show all original rules.

238

4. Check minimum number of events

None

238

5. Include endpoints

None

238

6. Filter based on genotype QC (FinnGen only)

231

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 231 164 67
Unadjusted period prevalence (%) 0.05 0.06 0.03
Median age at first event (years) 56.91 54.77 62.12

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
238
Matched controls
2380
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q44.6
ICD-10 Finland
Cystic disease of liver
+∞
307.7
238
*
K76.80
ICD-10 Finland
Hepatic cyst
267.2
100.0
96
6
127
Kela drug reimbursment
Transplant complication
39.0
66.3
42
13
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
775.0
62.8
59
*
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
237.0
55.6
55
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.6
47.0
87
168
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
7.5
39.7
69
123
JJA31
NOMESCO Finland
Laparoscopic marsupialisation of cyst of liver
+∞
35.3
33
*
JJ5KT
NOMESCO Finland
Sclerotherapy of liver cyst
+∞
30.9
29
*
JN3AD
NOMESCO Finland
Abdominal CT examination
5.9
30.3
67
149
Z94.0
ICD-10 Finland
Kidney transplant status
73.5
28.7
32
5
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
8.1
28.6
42
61
JN3BD
NOMESCO Finland
Extensive abdominal CT
5.6
27.1
62
141
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
27.1
27.1
37
16
L04AA06
ATC
mycophenolic acid; systemic
25.5
26.6
37
17
TK800
NOMESCO Finland
Hemodialysis
23.3
25.2
36
18
L04AD02
ATC
tacrolimus; systemic
50.5
22.9
27
6
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
19.6
22.6
34
20
Z94.4
ICD-10 Finland
Liver transplant status
69.4
22.3
25
*
JJC00
NOMESCO Finland
Allogenic transplantation of liver
88.7
22.1
24
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
63.3
20.3
23
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.5
20.0
131
621
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
34.7
19.7
25
8
A11CC03
ATC
alfacalcidol; systemic
16.0
19.2
31
22
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.3
18.5
110
486
Z49.1
ICD-10 Finland
Extracorporeal dialysis
36.1
18.3
23
7
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.8
18.1
36
71
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
6.0
17.9
34
64
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
30.1
16.8
22
8
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
97.0
16.8
18
*
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
182.2
16.7
17
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
15.1
16.4
27
20
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.1
16.0
52
153
JJ1AT
NOMESCO Finland
Puncture of lesion of liver with ultrasound guidance
170.8
15.7
16
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
15.5
145
808
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
31.0
15.5
20
7
B03XA02
ATC
darbepoetin alfa; parenteral
15.4
15.4
25
18
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
60.7
15.0
17
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
38.7
14.7
18
5
A12AA04
ATC
calcium carbonate; oral
17.6
13.7
21
13
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.4
13.7
29
60
H02AB04
ATC
methylprednisolone; systemic
3.4
13.5
59
211
V03AE02
ATC
sevelamer; oral
53.1
13.0
15
*
L04AD01
ATC
ciclosporin; systemic
12.0
12.3
22
20
C08CA02
ATC
felodipine; oral
4.1
12.0
36
99
N18.8
ICD-10 Finland
Other chronic renal failure
12.7
11.6
20
17
205
Kela drug reimbursment
Chronic hypertension
2.7
11.6
86
411
7531A
ICD-9 Finland
Congenital anomalies of urinary system, Cystic kidney disease
+∞
11.5
11
*
JJ5AT, ,
NOMESCO Finland
125.8
11.5
12
*
N02AX02
ATC
tramadol; systemic, rectal
2.5
11.2
131
775
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
10.3
10.5
20
21
V03AE01
ATC
polystyrene sulfonate; oral
34.2
10.4
13
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
19.9
10.4
15
8
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
10.3
69
310
WX402
NOMESCO Finland
General anaesthesia
2.7
10.2
70
319
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
8.2
10.2
22
29
C03CA01
ATC
furosemide; systemic
2.4
9.5
91
483
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
31.4
9.5
12
*
N18.0
ICD-10 Finland
End-stage renal disease
31.4
9.5
12
*
KAC00
NOMESCO Finland
Nephrectomy
104.0
9.5
10
*
Q61.1
ICD-10 Finland
Polycystic kidney, autosomal recessive
+∞
9.4
9
*
UJF30
NOMESCO Finland
Ileoscopy through colon
3.3
9.4
40
139
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
38.3
9.1
11
*
JN4AD
NOMESCO Finland
Body CT examination
3.3
9.0
38
131
R50.9
ICD-10 Finland
Fever, unspecified
2.8
8.9
50
204
J01MA02
ATC
ciprofloxacin; systemic
2.3
8.8
110
652
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
28.7
8.6
11
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
8.5
81
426
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
93.2
8.5
9
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
6.9
8.4
20
31
Q61.99
ICD-10 Finland
Cystic kidney disease, unspecified
+∞
8.4
8
*
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
12.3
8.2
14
12
KA1AE
NOMESCO Finland
Kidney ultrasound examination
8.2
8.0
17
22
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
7.9
37
136
Z2446
NOMESCO Finland
Social worker
3.8
7.8
25
72
TPH07
NOMESCO Finland
Cathetrisation of artery
3.0
7.8
38
143
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
19.1
7.7
11
6
C02AC05
ATC
moxonidine; oral
4.5
7.6
19
45
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
82.6
7.5
8
*
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
4.1
7.4
21
55
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.4
7.4
19
46
JJA30
NOMESCO Finland
Marsupialisation of cyst of liver
+∞
7.3
7
*
7516D
ICD-9 Finland
Other congenital anomalies of digestive system, Anomalies of gallbladder, bile ducts and liver[HEPAR POLYCYSTICUM]
+∞
7.3
7
*
Q61.0
ICD-10 Finland
Congenital single renal cyst
+∞
7.3
7
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
7.3
48
211
3AC01, ,
NOMESCO Finland
16.4
7.3
11
7
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
31.0
7.2
9
*
R4110
NOMESCO Finland
Physiotherapy
2.2
7.0
83
473
137
Kela drug reimbursment
Uraemia requiring dialysis
14.3
7.0
11
8
UJF32
NOMESCO Finland
Coloscopy
2.2
6.9
80
450
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.5
6.9
17
40
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
41.3
6.8
8
*
KBV00
NOMESCO Finland
Insertion of stent into ureter
41.3
6.8
8
*
V03AE03
ATC
lanthanum carbonate; oral
23.3
6.7
9
*
C08CA13
ATC
lercanidipine; oral
2.4
6.5
49
230
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
71.7
6.5
7
*
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
27.5
6.3
8
*
A41.8
ICD-10 Finland
Other specified sepsis
8.0
6.2
13
17
J01MA12
ATC
levofloxacin; systemic
2.3
6.2
55
277
R18
ICD-10 Finland
Ascites
9.0
6.1
12
14
RD210, ,
NOMESCO Finland
9.0
6.1
12
14
K83.0
ICD-10 Finland
Cholangitis
10.4
6.1
11
11
JAF30
NOMESCO Finland
Repair of umbilical hernia using prosthetic material
10.4
6.1
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
36
29
14.45
37.51
2.0
2.3
3.42
130.58
u/ml
0.48
36
29
88
226
5.59
34.24
10.9
2.5
5.75
7.29
umol/l
0.73
83
200
185
872
6.04
33.77
14.3
4.3
35.66
35.88
g/l
0.24
178
818
40
56
8.38
28.05
9.6
3.3
1.88
1.54
mg/l
1.22
40
50
31
32
10.99
27.37
1.6
1.1
289.71
306.07
u/ml
0.05
31
15
181
929
4.96
27.17
16.8
12.5
1.14
1.24
inr
1.15
55
276
50
94
6.47
26.73
2.8
3.4
262.29
1894.08
u/ml
0.57
45
81
31
35
10.03
25.64
1.8
1.2
135.00
101.83
u/ml
—
5
6
62
148
5.31
25.59
14.5
6.2
—
—
—
0
0
32
38
9.57
25.49
1.7
1.3
—
—
—
0
0
81
267
4.08
21.88
6.7
2.4
20.72
22.23
%
0.54
70
230
32
52
6.95
19.47
1.5
1.2
—
—
—
0
0
134
658
3.37
19.05
4.5
2.4
62.81
62.05
u/l
0.04
122
608
130
628
3.36
18.97
13.4
4.1
7.40
7.40
ph
0.03
19
121
161
910
3.38
17.59
16.7
5.4
1.21
1.22
mmol/l
0.64
154
825
168
985
3.40
17.04
19.1
6.2
1.20
1.22
mmol/l
2.01
152
840
26
16
18.07
16.99
1.1
1.2
—
—
—
0
0
59
184
3.93
16.83
3.0
1.6
—
—
—
0
0
23
10
25.28
16.78
6.0
3.0
—
—
—
0
0
26
18
16.05
16.27
2.2
2.3
—
—
—
0
0
20
6
36.18
16.01
1.1
1.0
—
—
—
0
0
222
1596
6.82
15.98
21.5
7.4
88.79
79.19
u/l
1.92
217
1497
61
204
3.68
15.64
3.1
1.5
—
—
—
0
0
19
5
41.03
15.63
1.1
1.0
—
—
—
0
0
55
182
3.63
14.24
5.9
2.2
41.02
28.64
u/l
1.67
49
148
102
487
2.92
14.23
9.8
4.0
—
—
—
0
0
21
13
17.57
13.73
3.5
1.1
—
—
—
0
0
62
238
3.17
12.56
2.7
4.4
3.90
27.13
ug/l
0.73
45
200
62
245
3.07
11.90
3.0
1.7
—
—
—
0
0
102
525
2.65
11.87
5.7
2.8
353.35
6871.17
umol/l
2.40
95
457
114
623
2.59
11.68
3.6
2.1
—
—
—
0
0
38
112
3.85
11.53
9.6
5.3
23.92
25.20
mmol/l
1.79
38
112
21
38
5.96
11.39
9.4
3.7
—
—
—
0
0
148
923
2.60
11.38
3.9
2.4
—
—
—
0
0
38
113
3.81
11.38
1.9
1.4
—
—
—
0
0
102
536
2.58
11.25
7.7
2.9
—
—
—
0
0
188
1329
2.97
11.07
9.8
3.1
88.75
45.80
u/l
4.13
178
1242
90
454
2.58
10.71
3.0
2.2
2.82
3.33
mg/l
1.32
73
388
139
859
2.49
10.64
3.8
2.3
81.91
77.75
nmol/l
1.04
133
760
65
279
2.83
10.64
2.6
2.0
—
—
—
0
0
58
234
2.96
10.64
11.6
5.5
103.90
103.57
mmol/l
0.17
58
234
19
19
10.76
10.22
4.5
1.6
0.90
0.98
g/l
0.30
19
19
90
465
2.50
10.08
6.8
3.7
—
—
—
0
0
17
14
12.97
10.02
1.2
1.1
—
—
—
0
0
151
1002
2.39
9.40
11.4
5.8
0.52
0.57
e9/l
1.57
134
871
151
1004
2.38
9.33
11.4
5.8
0.03
0.04
e9/l
2.09
134
872
145
948
2.36
9.31
11.5
6.4
—
—
—
0
0
59
257
2.72
9.28
1.4
1.2
—
—
—
0
0
105
599
2.35
9.28
7.7
3.1
25.84
145.19
e6/l
0.56
87
455
99
551
2.36
9.25
8.0
3.0
0.14
0.42
e6/l
2.28
82
402
153
1026
2.38
9.23
11.4
5.8
1.55
1.89
e9/l
2.57
137
918
154
1039
2.37
9.11
11.5
6.2
0.18
0.18
e9/l
0.02
139
922
13
7
19.54
9.03
2.2
1.7
—
—
—
0
0
93
508
2.36
9.03
10.5
7.0
—
—
—
0
0
67
315
2.57
9.03
5.3
2.8
1.09
3.13
e6/l
2.15
44
167
30
89
3.71
8.97
8.9
6.6
—
—
—
0
0
166
1169
2.39
8.71
13.8
9.3
4.25
3.98
e9/l
0.69
152
1025
138
900
2.27
8.69
11.6
5.7
0.64
0.69
%
0.49
130
833
141
933
2.25
8.50
11.8
6.1
8.45
8.58
%
0.19
133
871
140
928
2.24
8.35
11.6
5.7
2.77
2.80
%
0.06
131
864
141
943
2.22
8.15
11.3
5.7
61.22
57.38
%
3.51
133
881
142
956
2.20
8.03
11.6
5.9
24.53
27.88
%
3.35
134
893
18
28
6.86
7.57
9.9
3.5
82.50
61.77
%
4.05
18
28
128
847
2.11
7.33
5.6
2.7
150.37
114.64
ug/l
1.47
121
776
131
877
2.10
7.25
17.9
10.0
0.00
0.00
e9/l
0.36
107
725
10
5
20.78
7.19
1.0
1.2
—
—
—
0
0
101
626
2.07
6.75
5.2
3.7
6.43
8.64
mg/mmol
0.46
79
373
110
707
2.03
6.63
9.5
3.7
59.37
65.95
e6/l
0.07
89
499
16
26
6.52
6.59
1.6
1.1
—
—
—
0
0
70
380
2.19
6.59
6.4
2.9
500.98
521.43
mosm/kgh2o
0.38
64
327
96
589
2.06
6.56
4.6
3.2
39.19
48.83
mg/l
0.31
80
367
99
618
2.03
6.42
4.7
3.0
6.64
7.34
mmol/l
0.95
93
512
45
204
2.49
6.39
9.0
5.7
-0.28
1.26
mmol/l
2.51
39
172
209
1738
2.66
6.03
38.9
16.2
14.42
15.13
%
1.62
203
1720
45
211
2.40
5.93
4.1
3.3
1.71
1.74
%
0.07
38
195
26
93
3.02
5.78
9.5
2.8
1.32
1.19
%
0.21
26
93
98
629
1.95
5.73
3.6
2.9
—
—
—
0
0
41
192
2.37
5.40
2.0
1.4
—
—
—
0
0
25
91
2.95
5.40
9.7
2.8
0.66
0.66
%
0.01
25
91
36
159
2.49
5.38
4.8
3.1
61.45
70.00
e9/l
0.86
22
122
63
354
2.06
5.31
3.6
3.6
589.24
138.84
ng/l
0.65
55
268
20
65
3.27
5.20
3.9
3.0
22.20
21.66
s
0.18
20
58
53
281
2.14
5.19
1.5
1.2
—
—
—
0
0
117
816
1.85
5.16
6.2
3.6
5.75
5.80
ph
—
8
57
105
709
1.86
5.13
4.7
3.4
2.35
2.35
mmol/l
0.23
93
628
174
1380
1.97
5.09
7.9
4.3
—
—
—
0
0
189
1544
2.09
5.06
5.6
4.2
15.48
12.12
mm/h
2.02
181
1422
137
1014
1.83
4.89
6.9
3.8
0.00
0.00
estimate
0.50
32
215
226
2004
3.53
4.88
36.3
13.5
21.81
21.85
mg/l
0.01
203
1543
179
1443
1.97
4.86
4.5
3.9
—
—
—
0
0
137
1018
1.81
4.79
8.9
5.1
0.00
0.00
estimate
-0.00
32
198
18
58
3.28
4.75
3.6
2.9
—
—
—
0
0
138
1031
1.81
4.71
6.9
3.8
0.00
0.00
estimate
-0.00
33
192
78
497
1.85
4.46
1.5
1.4
—
—
—
0
0
46
252
2.02
4.09
1.6
1.4
—
—
—
0
0
112
812
1.72
4.04
2.3
2.0
94.33
95.69
pmol/l
0.12
63
393
9
14
6.63
4.02
4.7
5.1
9.97
11.91
%
—
9
14
231
2142
3.67
4.02
38.4
16.1
106.09
74.45
umol/l
5.54
231
2142
35
174
2.19
4.00
6.9
3.6
—
—
—
0
0
58
362
1.80
3.46
2.0
1.7
1114.08
1224.80
nmol/l
0.52
48
268
13
37
3.66
3.46
1.5
1.1
—
—
—
0
0
7
10
7.17
3.38
1.9
1.9
134.79
63.70
ug/l
—
7
10
10
25
4.13
3.12
2.1
1.1
—
—
—
0
0
26
127
2.18
3.11
2.5
1.9
1.20
1.43
g/l
0.32
26
117
80
561
1.64
3.10
7.6
4.1
0.00
0.00
estimate
-0.00
31
200
13
45
3.00
3.07
2.2
5.3
—
—
—
0
0
73
512
1.61
2.79
1.7
1.5
20.22
22.21
nmol/l
0.68
65
427
5
6
8.48
2.76
1.2
1.0
2021.80
1240.67
miu/ml
—
5
6
81
584
1.59
2.76
2.1
1.7
1.12
1.36
mmol/l
3.76
75
487
109
841
1.55
2.76
2.7
2.2
—
—
—
0
0
24
121
2.09
2.66
1.4
1.2
—
—
—
0
0
35
203
1.85
2.63
1.9
1.7
—
—
—
0
0
59
399
1.64
2.59
3.7
2.7
2.47
2.45
mmol/l
0.33
52
356
12
44
2.82
2.59
8.9
2.2
—
—
—
0
0
6
11
5.56
2.56
3.8
2.9
—
—
—
0
0
22
110
2.10
2.50
5.1
3.1
7.37
7.41
ph
—
5
15
224
2085
2.26
2.38
29.4
12.7
—
—
—
0
0
7
17
4.21
2.38
1.1
1.3
—
—
—
0
0
232
2215
2.88
2.25
48.8
20.0
38.67
40.04
%
3.86
216
2101
232
2216
2.86
2.25
47.9
20.1
231.71
253.24
e9/l
5.49
226
2166
232
2216
2.86
2.25
48.0
20.1
6.48
6.51
e9/l
0.07
225
2158
80
603
1.49
2.15
1.8
2.1
143.50
183.84
u/l
0.45
74
565
232
2217
2.84
2.10
47.9
20.1
4.32
4.46
e12/l
4.88
226
2159
15
69
2.25
2.09
1.9
2.2
144.41
315.84
ug/l
1.04
15
64
11
44
2.57
2.04
6.9
3.0
4.94
5.09
kpa
0.34
11
44
11
44
2.57
2.04
6.9
3.0
8.75
8.60
kpa
0.07
11
44
31
190
1.73
1.96
1.3
1.5
—
—
—
0
0
7
22
3.25
1.89
1.7
2.0
91.11
89.58
%
—
7
22
42
282
1.59
1.89
1.3
1.4
234.29
635.88
titre
—
7
68
6
17
3.59
1.85
4.5
2.6
—
—
—
0
0
7
23
3.10
1.81
1.0
2.7
—
—
—
0
0
9
36
2.56
1.76
4.9
2.7
3.02
5.08
e9/l
—
9
36
61
455
1.46
1.69
6.8
4.0
1.02
1.02
kg/l
—
5
61
6
19
3.21
1.67
1.3
2.5
4.67
2.98
nmol/l
—
6
19
11
49
2.31
1.66
1.3
1.3
—
—
—
0
0
25
152
1.72
1.64
2.0
2.2
—
—
—
0
0
11
50
2.26
1.59
7.0
2.9
7.41
7.42
ph
0.68
11
45
6
20
3.05
1.59
2.7
1.3
—
—
—
0
0
215
2017
1.68
1.58
5.9
4.6
4.54
4.76
mmol/l
2.68
205
1869
27
170
1.66
1.57
7.4
3.9
—
—
—
0
0
206
1915
1.56
1.55
7.6
5.8
38.14
39.86
mmol/mol
2.62
198
1785
28
179
1.64
1.54
5.0
4.0
0.92
1.03
%
0.12
13
66
0
45
0.00
1.51
0.0
4.8
—
23.68
—
0
28
9
37
2.49
1.49
5.9
3.1
57.22
59.78
%
—
9
37
9
39
2.36
1.44
10.0
2.6
—
—
—
0
0
5
17
2.98
1.36
1.0
1.2
—
—
—
0
0
35
244
1.51
1.36
3.1
2.1
160.20
133.98
ug/g
0.22
30
190
211
1985
1.56
1.35
5.9
4.7
5.72
5.93
mmol/l
1.98
198
1829
9
176
0.49
1.35
1.4
1.4
—
—
—
0
0
59
739
0.73
1.27
3.0
3.0
—
—
—
0
0
6
26
2.34
1.19
1.0
1.0
—
—
—
0
0
13
72
1.85
1.17
4.0
2.9
0.15
0.21
g/l
—
8
24
216
2054
1.56
1.17
6.6
5.2
2.64
2.80
mmol/l
2.19
203
1891
91
768
1.30
1.14
2.8
3.8
88.17
29.97
ng/l
0.40
63
538
16
96
1.71
1.13
2.1
1.5
—
—
—
0
0
17
104
1.68
1.13
2.1
2.3
—
—
—
0
0
7
31
2.30
1.11
5.3
2.5
—
—
—
0
0
7
31
2.30
1.11
1.9
1.4
—
—
—
0
0
56
445
1.34
1.07
2.2
1.8
1.89
1.10
mg/l
1.19
41
354
7
33
2.15
1.06
1.0
1.1
—
—
—
0
0
23
156
1.53
1.03
4.7
3.9
0.56
0.55
%
—
9
47
5
23
2.20
0.98
2.2
1.2
—
—
—
0
0
24
167
1.49
0.96
5.2
4.1
0.44
0.22
%
—
9
54
14
85
1.69
0.96
1.3
1.2
—
—
—
0
0
199
1881
1.35
0.95
4.7
4.9
1.94
2.55
mu/l
0.47
187
1726
18
118
1.57
0.94
9.7
4.1
—
—
—
0
0
9
52
1.76
0.93
2.0
1.2
—
—
—
0
0
5
102
0.48
0.92
1.4
2.1
14.60
12.96
nmol/l
—
5
94
22
153
1.48
0.89
5.6
4.2
0.00
0.03
%
—
7
40
0
24
0.00
0.79
0.0
4.1
—
51.49
—
0
8
0
25
0.00
0.79
0.0
1.8
—
—
—
0
0
22
158
1.43
0.78
1.7
1.4
—
—
—
0
0
13
83
1.60
0.76
4.4
3.2
—
—
—
0
0
10
159
0.61
0.75
1.9
1.3
—
—
—
0
0
14
92
1.55
0.74
1.5
1.6
—
—
—
0
0
16
110
1.49
0.70
2.2
3.0
0.15
0.18
e6/l
0.07
16
105
5
27
1.87
0.69
1.6
1.6
32.00
31.67
pg
—
5
27
32
401
0.77
0.68
1.3
1.3
10.49
40.08
iu/ml
—
7
134
208
2008
1.28
0.59
6.0
4.6
1.52
1.52
mmol/l
0.08
196
1850
33
268
1.27
0.56
1.2
1.3
—
—
—
0
0
11
74
1.51
0.54
1.5
1.4
0.22
0.24
g/l
0.18
11
74
48
411
1.21
0.52
1.6
1.4
2.67
2.33
g/l
0.49
34
243
167
1589
1.17
0.49
4.1
4.1
15.15
14.77
pmol/l
1.22
161
1448
53
461
1.19
0.49
4.2
5.0
2.01
2.74
ug/l
0.49
48
417
11
78
1.43
0.44
1.5
1.3
1.10
1.21
g/l
0.52
11
78
23
185
1.27
0.44
12.1
4.0
—
—
—
0
0
5
32
1.57
0.42
2.8
1.7
—
—
—
0
0
5
33
1.53
0.41
1.4
1.8
—
—
—
0
0
11
79
1.41
0.41
1.3
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
63
573
1.14
0.34
5.0
3.4
—
—
—
0
0
6
87
0.68
0.33
1.2
1.1
—
—
—
0
0
6
46
1.31
0.33
5.8
2.7
21.17
117.32
ug/min
—
6
28
7
52
1.36
0.31
7.1
2.6
—
—
—
0
0
10
77
1.31
0.26
2.2
3.1
—
—
—
0
0
9
76
1.19
0.25
1.3
1.6
—
—
—
0
0
6
82
0.72
0.24
18.2
9.9
—
—
—
0
0
0
11
0.00
0.21
0.0
8.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
153.47
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
74.85
—
0
13
0
13
0.00
0.21
0.0
16.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
17.66
—
0
14
18
156
1.17
0.19
1.2
1.2
81.97
159.18
iu/ml
—
6
63
42
454
0.91
0.19
1.3
1.2
1.70
1.36
u/ml
—
8
138
59
624
0.93
0.16
3.8
3.7
—
—
—
0
0
9
80
1.13
0.15
1.2
1.3
37.60
26.69
iu/l
—
9
67
197
1941
1.09
0.15
5.4
4.1
1.13
1.28
mmol/l
4.38
183
1783
9
81
1.12
0.15
16.1
3.5
—
—
—
0
0
8
99
0.80
0.14
7.5
3.8
—
—
—
0
0
10
117
0.85
0.13
1.1
1.5
—
—
—
0
0
36
385
0.92
0.13
1.3
1.3
1.49
13.39
u/ml
2.36
14
151
30
280
1.08
0.11
3.1
3.0
0.75
0.79
ug/l
0.07
21
188
10
87
1.16
0.09
6.0
1.8
—
—
—
0
0
12
134
0.89
0.09
5.1
2.6
—
—
—
0
0
13
144
0.90
0.08
1.4
1.2
—
—
—
0
0
6
57
1.05
0.08
1.0
1.2
—
—
—
0
0
5
62
0.80
0.08
1.2
1.3
—
3.27
—
0
12
9
88
1.02
0.07
1.0
1.1
—
—
—
0
0
44
424
1.05
0.06
1.6
1.7
522.18
458.09
pmol/l
0.77
39
359
14
152
0.92
0.06
2.6
2.5
—
20.53
—
0
7
15
139
1.08
0.05
1.3
1.3
—
—
—
0
0
18
186
0.97
0.00
1.5
1.5
—
—
—
0
0
14
137
1.02
0.00
1.3
1.3
—
26.61
—
0
9
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
9.1
—
1072.43
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
20.1
—
2209.14
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
172.23
—
0
6

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_CYSTIC_DISEASE_OF_LIVER – Cystic disease of liver

GWS hits: 16

This endpoint is excluded (different definition than used in FinnGen).