≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback

Other congenital malformations of upper alimentary tract

EFO Endpoint Browser PheWeb

Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q40
  • Cause of death: ICD-10 — Q40

2 out of 7 registries used, show all original rules.

258

4. Check minimum number of events

None

258

5. Include endpoints

None

258

6. Filter based on genotype QC (FinnGen only)

249

Control definitions (FinnGen only)

Control exclude
Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q3[8-9]|Q4[0-5]
Name in latin
Aliae malformationes congenitae tractus digestorii superioris

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2520 841 1677
Only index persons 1862 650 1212
Unadjusted period prevalence (%)
Whole population 0.04 0.02 0.05
Only index persons 0.04 0.02 0.05
Median age at first event (years)
Whole population 5.28 15.36 0.17
Only index persons 15.21 41.69 1.01

-FinnGen-

Key figures

All Female Male
Number of individuals 249 113 136
Unadjusted period prevalence (%) 0.05 0.04 0.06
Median age at first event (years) 62.10 58.70 64.93

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
258
Matched controls
2580
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q40.9
ICD-10 Finland
Congenital malformation of upper alimentary tract, unspecified
+∞
245.9
195
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
19.3
112.0
209
466
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
7.6
37.8
62
103
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
6.9
37.6
69
129
Q40.1
ICD-10 Finland
Congenital hiatus hernia
+∞
30.8
29
*
SPAT1101
SPAT
Orthostatic test
8.9
28.4
38
49
SPAT1301
SPAT
No procedures
4.1
28.0
132
525
UJF32
NOMESCO Finland
Coloscopy
3.9
24.3
110
417
SPAT1249
SPAT
Treatment-related counselling outside office
3.7
23.4
148
694
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
36.1
23.0
29
9
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.6
22.9
66
180
Q40.0
ICD-10 Finland
Congenital hypertrophic pyloric stenosis
+∞
22.2
21
*
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.0
19.7
47
109
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
7.1
18.8
30
47
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
4.3
17.5
52
143
SPAT1210
SPAT
Application of cast or individual aid
7.2
17.4
27
41
K29.7
ICD-10 Finland
Gastritis, unspecified
7.5
17.3
26
38
A02BC03
ATC
lansoprazole; oral
3.1
17.0
106
473
-, ,
ICD-10 Finland
19.6
16.8
25
14
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.2
15.1
75
290
SPAT1312
SPAT
General health counselling
2.8
14.2
117
595
SPAT1153
SPAT
Removal of sutures
2.8
14.2
111
550
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
14.7
14.0
23
17
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
11.9
13.3
24
22
SPAT1285
SPAT
Provision of consultation response
5.5
12.5
25
49
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
12.5
57
208
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
9.4
12.3
25
29
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.7
12.1
43
133
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
11.9
11.8
21
19
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
11.3
146
893
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.5
11.2
99
510
G40.9
ICD-10 Finland
Epilepsy, unspecified
5.5
11.0
22
43
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
114.5
10.5
11
*
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
3.1
10.5
49
180
JDH60
NOMESCO Finland
Pyloromyotomy
+∞
10.5
10
*
SPAT1260
SPAT
Consultation of another employee
2.8
10.4
65
280
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.7
10.4
35
104
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
4.0
10.3
31
85
R13
ICD-10 Finland
Dysphagia
3.8
10.3
33
95
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.3
9.9
129
779
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
7.7
9.7
22
31
SPAT1263
SPAT
Sampling
2.3
9.4
125
758
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.0
9.2
27
73
T18.1
ICD-10 Finland
Foreign body in oesophagus
16.4
9.1
14
9
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.9
9.1
48
188
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
9.1
104
590
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
5.2
9.0
19
39
SPAT1104
SPAT
Monitoring of emergency patient
4.2
8.9
25
65
WX320
NOMESCO Finland
Spinalanesthesy
0.2
8.9
7
374
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
8.7
8.7
18
22
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.8
8.7
49
199
N03AG01
ATC
valproic acid; systemic, rectal
3.9
8.7
27
76
SPAT1229
SPAT
Assessment of need for aid
3.7
8.3
27
78
SPAT1310
SPAT
Counselling related to known health issue
2.2
8.1
99
572
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.2
8.1
88
485
SPAT1053
SPAT
Memory test
2.6
8.0
52
227
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.7
7.9
26
76
M01AC06
ATC
meloxicam; systemic, rectal
2.1
7.7
102
605
R03AC03
ATC
terbutaline; inhalant
2.7
7.7
44
180
A02BC02
ATC
pantoprazole; systemic
2.2
7.6
176
1287
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.9
7.3
38
147
N03AF02
ATC
oxcarbazepine; oral
4.5
7.3
18
42
Q40.8
ICD-10 Finland
Other specified congenital malformations of upper alimentary tract
+∞
7.3
7
*
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
+∞
7.3
7
*
181
Kela drug reimbursment
Retigabine and vigabatrin
+∞
7.3
7
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.0
7.2
21
56
A02BC04
ATC
rabeprazole; oral
3.1
7.2
31
108
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
10.5
7.1
13
13
TKE00
NOMESCO Finland
Needle biopsy of prostate
4.0
7.0
20
53
183
Kela drug reimbursment
Lamotrigin and topiramate
9.7
6.9
13
14
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
6.7
54
259
H03AA01
ATC
levothyroxine sodium; systemic
2.3
6.7
62
316
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
23.2
6.7
9
*
L04AX01
ATC
azathioprine; systemic
4.4
6.7
17
41
A02BC05
ATC
esomeprazole; systemic
2.0
6.5
108
687
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
6.5
48
222
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
71.5
6.5
7
*
SPAT1255
SPAT
Intravenous administration of medicine
3.2
6.3
25
83
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
27.4
6.3
8
*
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
27.4
6.3
8
*
GD1AD
NOMESCO Finland
Thorax CT examination
3.4
6.2
23
73
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
4.3
6.2
16
39
WX100
NOMESCO Finland
Conjunctival surface anesthesia
0.1
6.2
*
179
A03FA02
ATC
cisapride; oral, rectal
3.1
6.2
27
95
AA1AD
NOMESCO Finland
CT of head and brain
2.1
6.1
76
434
Z98.8
ICD-10 Finland
Other specified postsurgical states
10.4
6.1
11
11
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.5
6.0
41
182

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
164
239
17.09
123.77
14.4
8.2
—
—
—
0
0
123
168
13.08
94.22
4.7
3.5
—
—
—
0
0
75
83
12.33
65.02
5.0
4.7
—
—
—
0
0
162
501
7.00
54.28
7.0
3.6
—
—
—
0
0
95
197
7.05
47.58
3.7
2.3
2.91
7.25
ug/l
2.56
87
176
161
571
5.84
43.95
7.1
3.9
0.00
0.02
estimate
—
8
190
65
135
6.10
31.50
5.5
7.3
—
—
—
0
0
50
100
5.96
24.91
3.4
7.4
0.67
0.68
%
0.06
50
100
50
104
5.72
23.85
3.4
7.2
1.19
1.25
%
0.15
50
104
184
1023
3.78
21.71
7.2
3.7
0.00
0.00
estimate
—
9
214
183
1027
3.69
20.98
7.7
5.1
0.00
0.00
estimate
—
8
198
184
1042
3.67
20.66
7.2
3.7
0.00
0.00
estimate
—
8
189
128
623
3.09
17.74
2.8
2.1
140.53
220.55
u/l
1.45
116
591
91
374
3.21
16.75
3.2
3.0
2.44
2.45
mmol/l
0.47
83
332
68
243
3.44
15.62
6.2
10.2
1.71
1.08
mmol/l
1.06
45
205
108
533
2.77
13.82
3.1
2.2
3.71
2.99
mg/l
2.43
98
461
125
678
2.64
13.08
3.4
3.4
2.36
2.36
mmol/l
0.15
118
601
120
643
2.62
12.81
3.4
2.6
88.85
62.97
u/l
0.34
113
596
64
250
3.07
12.46
7.5
5.5
1.67
1.80
mmol/l
0.13
49
191
150
908
2.56
12.22
7.6
5.1
35.71
35.61
g/l
0.08
144
854
63
247
3.05
12.17
1.7
1.6
—
—
—
0
0
136
791
2.52
12.01
6.0
3.9
20.81
40.72
ng/l
2.62
103
566
59
230
3.03
11.46
5.6
8.7
—
—
—
0
0
183
1268
2.52
10.41
10.2
10.1
4.15
4.04
e9/l
0.28
172
1091
51
200
2.93
9.71
6.7
10.4
1.61
1.34
mmol/l
0.84
51
193
203
1508
2.62
9.43
5.2
3.7
15.60
14.75
pmol/l
4.10
196
1355
193
1406
2.48
9.26
6.9
4.0
—
—
—
0
0
100
573
2.22
8.39
7.1
7.4
—
—
—
0
0
41
159
2.88
7.91
1.5
1.4
—
—
—
0
0
26
77
3.64
7.75
1.5
1.2
—
—
—
0
0
156
1090
2.09
7.56
6.7
7.2
11.66
13.81
umol/l
0.85
147
1038
133
885
2.04
7.27
3.4
2.7
104.81
122.05
ug/l
0.81
128
815
207
1632
2.36
7.12
9.0
7.6
85.46
85.70
u/l
0.02
201
1513
20
53
4.01
6.95
1.8
2.5
12.43
107.81
ug/min
—
6
29
240
2103
3.02
5.29
19.8
14.6
25.79
23.79
mg/l
0.36
192
1643
192
1542
1.96
5.24
5.2
4.2
10.70
11.81
mm/h
0.77
182
1408
23
81
3.02
5.24
3.3
1.9
1.56
4.59
ug/l
0.44
23
75
242
2141
3.10
5.02
25.4
17.3
4.00
3.99
mmol/l
0.29
237
2081
34
663
0.44
4.92
3.0
3.0
—
—
—
0
0
151
1142
1.78
4.81
7.8
6.4
1.99
2.01
e9/l
0.08
141
994
75
460
1.89
4.80
2.0
1.7
1.69
1.52
mg/l
0.10
51
347
93
614
1.80
4.69
3.5
3.0
—
—
—
0
0
135
996
1.75
4.62
12.0
7.6
1.18
1.21
mmol/l
4.89
126
913
140
1044
1.75
4.61
8.1
7.0
—
—
—
0
0
227
1971
2.26
4.51
5.9
4.5
4.42
4.57
mmol/l
1.33
216
1822
116
824
1.74
4.51
1.9
1.9
96.73
95.28
pmol/l
0.15
72
433
147
1117
1.73
4.48
7.8
6.2
0.50
0.59
e9/l
5.39
137
939
221
1901
2.13
4.47
5.5
4.0
1.32
1.26
mmol/l
0.88
209
1737
27
558
0.42
4.47
5.4
3.4
—
—
—
0
0
131
965
1.73
4.46
26.0
13.6
1.27
1.28
inr
0.03
12
275
147
1118
1.73
4.46
7.8
6.3
0.04
0.04
e9/l
0.08
137
941
150
1149
1.73
4.41
7.7
6.8
0.20
0.20
e9/l
0.04
140
989
89
594
1.76
4.26
3.9
4.0
—
—
—
0
0
89
595
1.76
4.23
3.8
3.2
67.85
160.85
mg/l
0.43
68
406
63
380
1.87
4.20
1.7
1.7
1944.42
1225.82
nmol/l
9.47
52
297
8
257
0.29
4.13
1.1
1.3
—
—
—
0
0
217
1874
1.99
4.05
6.2
4.4
2.00
1.99
mu/l
0.01
209
1686
216
1868
1.96
3.93
8.8
5.8
40.64
40.21
mmol/mol
0.25
206
1740
224
1962
2.08
3.92
5.7
4.4
1.42
1.46
mmol/l
0.73
211
1802
27
121
2.38
3.89
1.9
1.3
—
—
—
0
0
141
1090
1.65
3.78
13.5
7.7
1.18
1.21
mmol/l
3.53
131
938
157
1248
1.66
3.77
10.2
6.0
7.05
6.63
mmol/l
1.31
152
1173
227
2010
2.08
3.66
6.5
5.0
2.60
2.69
mmol/l
0.79
217
1850
8
13
6.31
3.53
1.0
1.0
—
—
—
0
0
92
652
1.64
3.40
4.4
3.1
7.19
7.61
mmol/l
0.44
87
555
18
394
0.42
3.35
3.4
3.8
78.17
217.10
ng/l
0.89
12
311
75
507
1.68
3.32
3.8
3.1
315.66
8176.15
umol/l
2.72
61
442
220
1947
1.88
3.26
6.7
4.6
6.13
5.97
mmol/l
1.08
211
1773
24
112
2.26
3.18
1.3
1.2
—
—
—
0
0
88
627
1.61
3.15
4.0
3.7
165.77
10.11
mg/mmol
0.49
71
407
39
223
1.88
3.03
2.5
2.6
0.21
0.21
g/l
0.17
39
210
238
2177
2.20
3.00
18.6
13.1
—
—
—
0
0
14
53
2.74
2.84
2.5
1.3
244.25
269.52
u/ml
—
8
25
5
7
7.26
2.56
1.0
1.9
—
—
—
0
0
7
16
4.47
2.49
1.3
1.6
—
—
—
0
0
35
207
1.80
2.46
3.1
3.6
83.42
71.95
e9/l
0.76
30
156
20
374
0.50
2.42
6.5
3.1
3.43
1.62
e6/l
0.37
13
209
10
34
3.02
2.30
1.1
1.7
—
—
—
0
0
8
23
3.55
2.29
3.1
2.8
—
—
—
0
0
11
43
2.63
2.10
1.2
1.3
98.73
97.80
pmol/l
0.01
11
43
5
10
5.07
2.08
1.0
1.6
—
—
—
0
0
6
155
0.37
1.97
1.2
1.4
—
—
—
0
0
0
54
0.00
1.87
0.0
2.1
—
—
—
0
0
6
17
3.59
1.85
2.0
2.2
29.17
34.37
mmol/l
—
6
17
7
23
3.10
1.81
1.4
1.4
—
—
—
0
0
16
81
2.04
1.79
2.4
1.3
—
—
—
0
0
12
54
2.28
1.76
3.6
1.5
—
—
—
0
0
81
638
1.39
1.64
3.5
3.3
0.42
0.48
e6/l
0.12
73
486
68
521
1.41
1.61
1.4
1.4
2.35
1.96
u/ml
0.10
28
134
9
37
2.48
1.49
1.2
1.8
—
—
—
0
0
14
250
0.53
1.49
1.2
1.3
—
—
—
0
0
39
273
1.50
1.46
1.1
1.4
824.62
493.11
titre
0.38
13
61
6
137
0.42
1.45
3.5
2.5
—
—
—
0
0
17
96
1.83
1.43
2.7
2.9
20.29
67.78
u/ml
1.05
17
91
77
615
1.36
1.41
3.3
3.2
—
—
—
0
0
56
424
1.41
1.41
1.4
1.7
468.00
450.57
pmol/l
0.15
44
352
32
449
0.67
1.29
4.3
3.0
538.54
556.08
mosm/kgh2o
0.12
26
381
160
1434
1.30
1.26
5.2
4.2
—
—
—
0
0
29
198
1.52
1.23
1.4
1.7
—
—
—
0
0
44
577
0.71
1.23
1.6
1.4
—
—
—
0
0
34
241
1.47
1.22
1.4
1.4
—
—
—
0
0
94
789
1.30
1.21
1.9
2.2
—
—
—
0
0
44
329
1.41
1.20
2.0
2.0
—
—
—
0
0
8
155
0.50
1.18
1.0
1.3
—
—
—
0
0
10
181
0.53
1.13
5.4
4.2
—
—
—
0
0
15
89
1.73
1.10
1.0
1.2
—
—
—
0
0
10
52
1.96
1.07
8.1
3.0
43.30
37.13
umol/l
—
10
47
29
206
1.46
1.04
2.9
2.1
325.23
363.88
nmol/l
0.54
22
195
5
109
0.45
1.03
1.6
1.5
—
—
—
0
0
11
187
0.57
1.02
1.9
1.5
—
—
—
0
0
7
36
1.97
0.98
8.3
15.2
70.09
60.45
%
—
7
36
7
37
1.92
0.94
1.0
1.0
—
—
—
0
0
6
27
2.25
0.94
1.0
1.1
—
8.57
—
0
6
91
783
1.25
0.93
5.1
5.3
2.56
2.73
ug/l
0.11
83
694
13
82
1.62
0.79
2.2
1.9
305.93
344.82
ug/l
0.13
13
77
0
24
0.00
0.79
0.0
2.0
—
—
—
0
0
0
28
0.00
0.76
0.0
1.6
—
—
—
0
0
6
107
0.55
0.74
3.7
3.6
—
—
—
0
0
5
25
2.02
0.73
1.4
1.2
—
—
—
0
0
14
204
0.67
0.72
1.5
2.2
32.07
32.95
u/l
0.03
14
168
5
27
1.87
0.69
2.8
2.3
—
—
—
0
0
12
178
0.66
0.67
1.2
1.2
—
—
—
0
0
0
20
0.00
0.60
0.0
2.6
—
570.80
—
0
10
0
20
0.00
0.60
0.0
1.0
—
258.70
—
0
10
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
33
266
1.28
0.59
1.4
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.9
—
—
—
0
0
39
322
1.25
0.58
1.3
1.3
153.39
32.04
iu/ml
—
8
108
15
107
1.43
0.56
1.9
2.3
—
—
—
0
0
88
791
1.17
0.55
4.6
4.0
16.24
86.86
e6/l
3.07
74
568
12
86
1.41
0.45
30.7
8.9
1.35
1.39
mg/l
0.10
12
79
5
33
1.53
0.41
1.2
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
192.29
—
0
15
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
171.75
—
0
16
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
42.45
—
0
11
0
17
0.00
0.41
0.0
1.3
—
5.55
—
0
11
0
17
0.00
0.41
0.0
2.2
—
—
—
0
0
94
1014
0.89
0.39
8.6
9.9
0.00
0.02
e9/l
0.64
88
804
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
8
115
0.69
0.38
13.4
15.5
—
—
—
0
0
14
179
0.77
0.37
6.9
4.4
0.75
0.87
%
—
8
75
60
663
0.88
0.36
2.7
2.4
—
—
—
0
0
6
41
1.47
0.36
3.7
1.1
4.15
3.91
mmol/l
—
6
36
11
82
1.36
0.34
1.9
1.8
—
—
—
0
0
6
45
1.34
0.34
4.0
1.3
1.50
218.36
e6/l
—
6
33
33
291
1.15
0.27
1.5
1.5
—
—
—
0
0
14
113
1.25
0.27
1.2
1.2
128.45
146.56
iu/ml
—
6
36
5
71
0.70
0.26
3.2
3.4
—
—
—
0
0
5
74
0.67
0.26
1.4
3.2
—
—
—
0
0
36
322
1.14
0.25
3.8
2.4
2.42
2.35
g/l
0.25
36
298
34
303
1.14
0.25
3.7
2.5
21.71
22.39
%
0.11
34
267
37
333
1.13
0.24
1.6
1.7
—
—
—
0
0
19
221
0.85
0.23
1.4
1.5
—
—
—
0
0
23
200
1.16
0.23
1.2
1.5
—
—
—
0
0
5
41
1.22
0.22
1.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
4.2
—
3.05
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.6
—
490.88
—
0
8
0
14
0.00
0.20
0.0
1.3
—
80.29
—
0
14
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
164.43
—
0
14
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
6
51
1.18
0.19
1.0
1.2
—
—
—
0
0
5
70
0.71
0.17
1.8
1.4
—
—
—
0
0
34
312
1.10
0.17
1.4
1.3
17.47
11.25
u/ml
0.15
18
112
29
269
1.09
0.12
1.3
1.2
—
—
—
0
0
14
124
1.14
0.11
1.3
1.3
—
59.69
—
0
8
5
61
0.82
0.08
3.2
4.3
—
—
—
0
0
5
62
0.80
0.08
1.0
1.1
—
—
—
0
0
6
73
0.82
0.07
1.7
1.4
—
—
—
0
0
6
73
0.82
0.07
1.7
1.4
—
—
—
0
0
6
74
0.81
0.07
1.7
1.4
—
—
—
0
0
6
74
0.81
0.07
1.7
1.4
—
—
—
0
0
15
137
1.10
0.07
4.5
2.5
—
—
—
0
0
7
80
0.87
0.07
1.0
1.1
—
—
—
0
0
16
148
1.09
0.06
1.9
1.7
1.13
1.16
g/l
0.06
16
137
47
485
0.96
0.05
1.6
1.4
2.19
2.36
g/l
0.37
39
276
71
694
1.03
0.05
4.1
3.4
13.14
147.01
e6/l
0.84
61
541
133
1320
1.02
0.02
3.2
3.3
68.75
47.98
u/l
1.20
120
1234
16
167
0.96
0.01
13.9
5.1
—
—
—
0
0
13
131
0.99
0.00
2.4
2.8
30.36
6.00
e9/l
0.54
13
109
59
593
0.99
0.00
3.2
4.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
5
54
0.92
0.00
1.2
1.1
—
0.53
—
0
38
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
12137.00
—
0
6
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
50
1.00
-0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
50
1.00
-0.00
1.4
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
57
0.87
-0.00
1.2
1.1
—
5.08
—
0
40
14
140
1.00
-0.00
1.9
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
60.50
—
0
6
7
77
0.91
-0.00
1.7
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
26.28
—
0
5

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT and mortality.

Females

Parameter HR [95% CI] p-value
Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT 1.843 [1.4, 2.43] < 0.001
Birth year 0.995 [0.99, 1.0] 0.266

During the follow-up period (1.1.1998 — 31.12.2019), 112 out of 751 females with Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT died.

Males

Parameter HR [95% CI] p-value
Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT 2.23 [1.68, 2.95] < 0.001
Birth year 0.985 [0.97, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 167 out of 1492 males with Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT died.

Mortality risk

Mortality risk for people of age

years, who have Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT.

N-year risk Females Males
1 0.224% 0.399%
5 1.109% 2.275%
10 2.602% 5.744%
15 5.149% 10.659%
20 8.668% 17.596%

Relationships between endpoints

↥

Index endpoint: Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT – Other congenital malformations of upper alimentary tract

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data