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Other congenital malformations of upper alimentary tract

EFO Endpoint Browser PheWeb

Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — Q40
  • Cause of death: ICD-10 — Q40

2 out of 7 registries used, show all original rules.

247

4. Check minimum number of events

None

247

5. Include endpoints

None

247

6. Filter based on genotype QC (FinnGen only)

247

Control definitions (FinnGen only)

Control exclude
Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Q3[8-9]|Q4[0-5]
Name in latin
Aliae malformationes congenitae tractus digestorii superioris

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2520 841 1677
Only index persons 1862 650 1212
Unadjusted period prevalence (%)
Whole population 0.04 0.02 0.05
Only index persons 0.04 0.02 0.05
Median age at first event (years)
Whole population 5.28 15.36 0.17
Only index persons 15.21 41.69 1.01

-FinnGen-

Key figures

All Female Male
Number of individuals 247 112 135
Unadjusted period prevalence (%) 0.05 0.04 0.06
Median age at first event (years) 60.18 58.70 61.41

-FinRegistry-

Age distribution of first events

01020304050607080900.0k0.2k0.4k0.6k0.8k1.0k1.2k1.4kAgeIndividuals

-FinnGen-

Age distribution of first events

01020304050607080051015202530354045505560AgeIndividuals

-FinRegistry-

Year distribution of first events

197019751980198519901995200020052010201520202022050100150200250300350400450500550600YearIndividuals

-FinnGen-

Year distribution of first events

19701975198019851990199520002005201020152020202301020304050607080YearIndividuals

-FinRegistry-

Cumulative Incidence Function

01020304050607080901000.00.10.20.30.40.50.60.70.80.91.0AgeProbability of first incidence (%)

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
224
Matched controls
2238
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q40.9
ICD-10 Finland
Congenital malformation of upper alimentary tract, unspecified
+∞
211.4
168
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
19.0
81.5
178
378
Q40.1
ICD-10 Finland
Congenital hiatus hernia
+∞
28.8
27
*
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
73.1
23.4
26
*
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
7.3
22.5
58
102
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
8.1
22.0
52
80
Q40.0
ICD-10 Finland
Congenital hypertrophic pyloric stenosis
+∞
18.0
17
*
SPAT1301
SPAT
No procedures
3.5
17.4
112
493
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
5.7
15.0
45
94
SPAT1249
SPAT
Treatment-related counselling outside office
3.2
14.9
122
614
UJF32
NOMESCO Finland
Coloscopy
3.4
14.3
89
368
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.6
14.1
53
142
A02BC03
ATC
lansoprazole; oral
3.2
13.9
92
397
SPAT1101
SPAT
Orthostatic test
8.0
13.6
31
44
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
16.4
13.4
21
14
-
ICD-10 Finland
NA
15.3
13.0
21
15
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.4
12.4
27
36
SPAT1312
SPAT
General health counselling
2.8
12.0
102
509
SPAT1153
SPAT
Removal of sutures
2.8
11.6
98
483
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.4
11.4
61
220
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
4.3
11.0
42
113
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
14.0
10.3
17
13
WX320
NOMESCO Finland
Spinalanesthesy
0.1
10.0
*
314
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
8.2
9.7
21
28
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
9.3
9.5
19
22
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.6
9.4
89
457
SPAT1260
SPAT
Consultation of another employee
3.1
9.1
57
225
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
25.2
9.0
12
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
8.8
116
700
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
9.6
8.7
17
19
SPAT1210
SPAT
Application of cast or individual aid
5.4
8.5
25
51
JDH60
NOMESCO Finland
Pyloromyotomy
+∞
8.4
8
*
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
34.7
8.1
10
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.4
8.0
39
130
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.3
7.8
109
662
G40.9
ICD-10 Finland
Epilepsy, unspecified
6.2
7.7
20
35
Z98.8
ICD-10 Finland
Other specified postsurgical states
26.0
7.6
10
*
Q40.8
ICD-10 Finland
Other specified congenital malformations of upper alimentary tract
+∞
7.3
7
*
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
3.0
7.3
42
158
K22.2
ICD-10 Finland
Oesophageal obstruction
31.1
7.2
9
*
K29.7
ICD-10 Finland
Gastritis, unspecified
5.3
7.2
21
43
183
Kela drug reimbursment
Lamotrigin and topiramate
12.6
7.2
12
10
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
7.1
7.0
16
24
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
6.9
45
181
R13
ICD-10 Finland
Dysphagia
4.2
6.8
25
65
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.7
6.8
29
87
SPAT1310
SPAT
Counselling related to known health issue
2.2
6.7
85
485
N02BE01
ATC
paracetamol; systemic, rectal
2.5
6.7
188
1516
A02BC04
ATC
rabeprazole; oral
3.9
6.6
26
73
SPAT1263
SPAT
Sampling
2.1
6.5
108
691
R03AC03
ATC
terbutaline; inhalant
3.0
6.4
39
149
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
+∞
6.3
6
*
SPAT1053
SPAT
Memory test
2.6
6.3
46
200
M01AC06
ATC
meloxicam; systemic, rectal
2.1
6.3
87
517
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.9
6.2
38
147
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.9
6.1
24
67

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
154
226
16.44
115.21
14.4
8.4
—
—
—
0
0
116
162
12.62
87.11
4.9
3.4
—
—
—
0
0
70
82
11.52
58.08
5.2
4.8
—
—
—
0
0
153
484
6.68
49.48
7.1
3.6
—
—
—
0
0
91
190
7.00
45.25
3.7
2.3
2.90
7.16
ug/l
2.36
83
170
152
541
5.70
41.10
7.2
3.9
0.00
0.02
estimate
—
7
179
54
70
9.59
40.82
5.0
3.6
3.91
3.84
mmol/l
0.42
54
60
62
132
5.94
29.22
5.4
7.3
—
—
—
0
0
110
449
3.61
21.47
6.9
5.0
—
—
—
0
0
46
101
5.37
20.59
3.5
7.4
1.15
1.27
%
0.32
46
101
175
980
3.70
20.19
7.3
3.7
0.00
0.00
estimate
—
6
193
174
984
3.60
19.47
7.8
5.1
0.00
0.00
estimate
—
7
189
175
998
3.58
19.22
7.3
3.7
0.00
0.00
estimate
—
7
180
77
279
3.56
17.59
7.1
8.2
104.31
104.03
mmol/l
0.22
77
269
123
601
3.08
16.93
2.8
2.2
142.14
224.18
u/l
1.43
111
572
65
238
3.35
14.33
6.1
10.1
1.72
1.12
mmol/l
0.91
42
198
84
362
3.00
14.00
2.3
3.0
2.44
2.45
mmol/l
0.37
76
320
103
508
2.76
13.21
2.9
2.2
3.69
3.00
mg/l
2.13
94
445
115
615
2.63
12.37
3.5
2.6
90.48
56.07
u/l
0.47
108
570
117
653
2.50
11.24
2.8
3.4
2.37
2.36
mmol/l
0.44
111
577
130
762
2.49
11.22
6.1
3.9
21.10
39.51
ng/l
2.22
98
540
142
873
2.47
10.95
7.1
5.1
35.85
35.64
g/l
0.17
136
820
60
243
2.94
10.90
7.8
5.6
1.68
1.76
mmol/l
0.08
42
184
60
250
2.85
10.31
9.0
5.6
—
—
—
0
0
55
223
2.89
9.91
5.9
8.8
—
—
—
0
0
175
1216
2.51
9.85
10.4
10.2
4.17
4.04
e9/l
0.31
164
1048
57
239
2.80
9.63
1.7
1.6
—
—
—
0
0
195
1449
2.64
9.11
5.1
3.7
15.54
14.73
pmol/l
3.66
189
1305
184
1345
2.44
8.67
7.0
4.0
—
—
—
0
0
47
194
2.76
8.11
7.2
10.5
1.59
1.32
mmol/l
0.88
47
183
40
154
2.91
7.84
1.5
1.4
—
—
—
0
0
96
557
2.18
7.78
7.4
7.3
—
—
—
0
0
149
1051
2.05
6.93
6.7
7.2
10.88
13.94
umol/l
1.72
140
1002
24
74
3.48
6.75
1.6
1.2
—
—
—
0
0
197
1566
2.27
6.39
8.9
7.7
85.58
86.01
u/l
0.04
192
1451
23
76
3.23
5.82
3.3
1.9
1.56
4.83
ug/l
0.44
23
70
18
51
3.73
5.72
1.9
2.4
12.43
113.69
ug/min
—
6
27
39
733
0.44
5.25
8.5
6.6
—
—
—
0
0
74
444
1.95
5.14
2.0
1.8
1.65
1.48
mg/l
0.11
50
338
183
1479
1.92
4.77
5.2
4.2
10.66
11.68
mm/h
0.67
174
1355
229
2020
2.83
4.67
20.0
14.6
26.03
23.72
mg/l
0.41
182
1576
88
578
1.81
4.54
3.7
3.0
—
—
—
0
0
34
640
0.46
4.45
3.0
3.0
—
—
—
0
0
231
2058
2.89
4.39
25.4
17.3
4.00
3.99
mmol/l
0.30
226
2001
129
954
1.74
4.37
11.6
7.7
1.18
1.21
mmol/l
3.88
119
872
143
1090
1.74
4.34
8.0
6.4
2.01
2.02
e9/l
0.03
134
946
217
1886
2.24
4.27
6.0
4.5
4.41
4.58
mmol/l
1.53
206
1745
111
792
1.73
4.24
1.7
1.9
96.41
95.97
pmol/l
0.04
68
414
26
533
0.43
4.23
5.6
3.4
—
—
—
0
0
211
1818
2.10
4.19
5.5
4.0
1.32
1.26
mmol/l
0.81
199
1664
60
362
1.87
4.01
1.7
1.7
1915.92
1220.53
nmol/l
9.70
50
281
139
1066
1.70
4.00
7.9
6.3
0.50
0.59
e9/l
5.41
130
898
85
571
1.74
3.98
3.8
3.1
58.66
168.27
mg/l
0.50
65
387
85
571
1.74
3.98
4.0
4.0
—
—
—
0
0
208
1794
2.01
3.95
6.1
4.4
2.01
2.00
mu/l
0.06
201
1617
139
1068
1.69
3.95
7.9
6.3
0.04
0.04
e9/l
0.06
130
902
142
1098
1.69
3.94
7.9
6.9
0.20
0.20
e9/l
0.01
133
950
26
115
2.41
3.87
2.1
1.3
—
—
—
0
0
74
482
1.76
3.83
3.7
3.1
313.48
8645.88
umol/l
2.73
60
417
8
245
0.30
3.70
1.1
1.3
—
—
—
0
0
214
1877
2.05
3.68
5.7
4.4
1.42
1.46
mmol/l
0.71
201
1726
151
1200
1.66
3.66
10.3
6.0
7.09
6.63
mmol/l
1.42
146
1125
206
1788
1.92
3.60
9.1
5.8
40.87
40.18
mmol/mol
0.43
196
1666
135
1046
1.64
3.59
13.0
7.8
1.19
1.21
mmol/l
2.85
126
898
108
793
1.64
3.54
9.0
8.5
1.14
1.24
inr
—
9
223
89
624
1.67
3.48
4.5
3.1
6.92
7.59
mmol/l
0.83
84
529
217
1924
2.05
3.45
6.5
5.0
2.59
2.70
mmol/l
0.91
207
1773
24
108
2.35
3.45
1.3
1.2
—
—
—
0
0
85
602
1.63
3.15
4.1
3.8
172.30
10.46
mg/mmol
0.49
68
391
18
379
0.43
3.05
3.4
3.8
78.17
222.29
ng/l
0.92
12
298
7
12
5.97
3.04
1.0
1.0
—
—
—
0
0
209
1864
1.79
2.78
6.7
4.6
6.15
5.97
mmol/l
1.29
200
1699
228
2093
2.16
2.74
18.6
13.2
—
—
—
0
0
7
15
4.77
2.61
1.3
1.5
—
—
—
0
0
36
212
1.82
2.57
2.6
2.5
0.21
0.21
g/l
0.05
36
200
5
7
7.26
2.56
1.0
1.9
—
—
—
0
0
10
33
3.12
2.55
2.2
1.6
—
—
—
0
0
10
33
3.12
2.55
2.2
1.6
—
—
—
0
0
10
33
3.12
2.55
2.2
1.6
—
—
—
0
0
10
33
3.12
2.55
1.1
1.8
—
—
—
0
0
10
33
3.12
2.55
2.2
1.6
—
—
—
0
0
13
51
2.64
2.48
2.6
1.3
180.00
257.83
u/ml
—
7
24
20
363
0.51
2.22
6.5
3.2
3.43
1.65
e6/l
0.37
13
204
5
10
5.08
2.08
1.0
1.9
—
—
—
0
0
7
21
3.40
1.98
3.4
3.0
—
—
—
0
0
201
1830
1.53
1.83
11.0
16.4
37.87
39.74
%
0.93
76
1360
7
23
3.10
1.81
1.4
1.4
—
—
—
0
0
10
41
2.50
1.78
1.2
1.2
104.10
99.96
pmol/l
—
10
41
66
498
1.44
1.72
1.4
1.4
2.43
2.03
u/ml
0.09
27
126
0
48
0.00
1.71
0.0
2.0
—
—
—
0
0
6
146
0.40
1.71
1.2
1.4
—
—
—
0
0
31
199
1.64
1.67
3.2
3.6
82.79
72.36
e9/l
0.57
26
149
54
400
1.45
1.54
1.4
1.7
466.86
454.97
pmol/l
0.10
43
336
9
37
2.49
1.49
1.2
1.8
—
—
—
0
0
40
551
0.67
1.49
1.6
1.4
—
—
—
0
0
29
189
1.61
1.48
1.4
1.7
—
—
—
0
0
15
80
1.93
1.48
2.5
1.3
—
—
—
0
0
11
53
2.13
1.40
3.8
1.5
—
—
—
0
0
37
260
1.50
1.37
1.1
1.4
786.67
502.76
titre
0.29
12
58
7
148
0.46
1.37
1.0
1.4
—
—
—
0
0
5
17
2.98
1.36
2.2
2.2
22.80
34.37
mmol/l
—
5
17
6
131
0.44
1.33
3.5
2.5
—
—
—
0
0
14
240
0.56
1.31
1.2
1.3
—
—
—
0
0
154
1374
1.32
1.30
5.3
4.3
—
—
—
0
0
76
615
1.34
1.28
3.5
3.3
0.44
0.50
e6/l
0.11
68
462
32
227
1.47
1.15
1.4
1.4
—
—
—
0
0
31
427
0.69
1.15
4.3
2.9
531.88
564.20
mosm/kgh2o
0.23
25
360
90
758
1.29
1.13
1.9
2.2
—
—
—
0
0
72
593
1.30
1.06
3.4
3.2
—
—
—
0
0
5
107
0.46
1.03
1.6
1.5
—
—
—
0
0
7
35
2.03
1.01
8.3
15.5
70.09
61.49
%
—
7
35
14
84
1.71
1.00
1.0
1.3
—
—
—
0
0
28
200
1.45
0.99
2.9
2.1
336.71
365.89
nmol/l
0.38
21
189
0
29
0.00
0.98
0.0
2.2
—
—
—
0
0
7
36
1.97
0.98
1.0
1.0
—
—
—
0
0
10
171
0.57
0.95
5.4
4.2
—
—
—
0
0
9
51
1.79
0.95
8.9
2.9
43.56
35.84
umol/l
—
9
43
6
27
2.25
0.94
1.0
1.1
—
8.57
—
0
6
41
317
1.35
0.93
1.9
2.0
—
—
—
0
0
11
179
0.60
0.88
1.9
1.5
—
—
—
0
0
39
306
1.33
0.82
1.3
1.3
153.39
33.18
iu/ml
—
8
102
0
24
0.00
0.79
0.0
2.0
—
—
—
0
0
0
27
0.00
0.78
0.0
1.4
—
—
—
0
0
86
750
1.23
0.77
5.1
5.3
2.58
2.75
ug/l
0.10
80
668
5
24
2.10
0.75
1.4
1.2
—
—
—
0
0
5
26
1.94
0.71
2.8
2.3
—
—
—
0
0
14
198
0.69
0.63
1.5
2.1
32.07
33.05
u/l
0.03
14
165
6
105
0.56
0.63
3.7
3.6
—
—
—
0
0
32
256
1.29
0.60
1.4
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
258.70
—
0
10
0
21
0.00
0.60
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
0
23
0.00
0.58
0.0
1.9
—
—
—
0
0
12
171
0.69
0.57
1.3
1.2
—
—
—
0
0
88
973
0.85
0.56
9.0
10.0
0.00
0.02
e9/l
0.64
82
773
56
632
0.85
0.45
2.8
2.5
—
—
—
0
0
11
78
1.43
0.44
1.9
1.9
—
—
—
0
0
14
105
1.35
0.42
1.9
2.3
—
—
—
0
0
5
33
1.53
0.41
1.2
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
42.45
—
0
11
0
16
0.00
0.41
0.0
2.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
171.75
—
0
16
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
34
289
1.20
0.40
3.7
2.5
21.71
22.77
%
0.19
34
255
36
308
1.20
0.40
3.8
2.4
2.42
2.36
g/l
0.22
36
285
7
104
0.66
0.40
1.1
2.4
1.32
1.47
g/l
—
7
91
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
2.4
—
467.56
—
0
9
8
112
0.70
0.38
13.4
15.4
—
—
—
0
0
83
765
1.13
0.36
4.7
4.0
16.77
88.20
e6/l
2.96
71
549
6
41
1.47
0.36
3.7
1.1
4.15
3.91
mmol/l
—
6
36
6
45
1.34
0.34
4.0
1.3
1.50
218.36
e6/l
—
6
33
34
297
1.17
0.31
1.4
1.3
17.47
11.74
u/ml
0.14
18
105
36
320
1.15
0.27
1.6
1.7
—
—
—
0
0
14
170
0.81
0.26
6.9
4.5
0.86
0.90
%
—
7
56
31
276
1.14
0.23
1.5
1.5
—
—
—
0
0
5
38
1.32
0.23
1.6
2.2
2.34
4.02
u/ml
—
5
33
18
210
0.85
0.23
1.4
1.5
—
—
—
0
0
5
40
1.26
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
4.2
—
3.05
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.2
—
482.43
—
0
7
0
13
0.00
0.21
0.0
1.3
—
73.92
—
0
13
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
164.43
—
0
14
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
22
194
1.15
0.19
1.2
1.5
—
—
—
0
0
10
81
1.24
0.19
36.2
9.2
1.35
1.40
mg/l
—
10
74
5
66
0.75
0.17
3.6
3.5
—
—
—
0
0
14
122
1.16
0.14
1.3
1.2
—
47.07
—
0
7
5
46
1.09
0.09
1.4
1.5
—
—
—
0
0
27
253
1.08
0.09
1.4
1.2
—
—
—
0
0
5
61
0.82
0.08
1.0
1.1
—
—
—
0
0
5
63
0.79
0.08
1.8
1.4
—
—
—
0
0
14
129
1.09
0.05
4.8
2.6
—
—
—
0
0
58
567
1.03
0.04
3.2
4.2
—
—
—
0
0
46
471
0.97
0.03
1.6
1.4
2.13
2.36
g/l
0.51
38
269
68
671
1.02
0.02
4.2
3.4
13.23
150.14
e6/l
0.82
60
521
14
133
1.06
0.01
1.9
1.6
—
—
—
0
0
126
1268
0.99
0.01
3.3
3.3
66.94
47.33
u/l
1.05
114
1189
15
146
1.03
0.00
1.9
1.7
1.00
1.16
g/l
0.42
15
135
6
66
0.91
0.00
1.7
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
7
74
0.94
0.00
1.7
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
0.00
1.7
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
12137.00
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
5
53
0.94
0.00
1.2
1.2
—
0.53
—
0
38
5
56
0.89
0.00
1.2
1.1
—
5.08
—
0
40
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
7
77
0.91
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
16
160
1.00
0.00
13.9
5.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
26.28
—
0
5
5
59
0.84
0.00
3.2
4.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
6
67
0.89
0.00
1.7
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
6
67
0.89
0.00
1.7
1.4
—
—
—
0
0
5
49
1.02
0.00
1.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT and mortality.

Females

Parameter HR [95% CI] p-value
Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT 1.843 [1.4, 2.43] < 0.001
Birth year 0.995 [0.99, 1.0] 0.266

During the follow-up period (1.1.1998 — 31.12.2019), 112 out of 751 females with Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT died.

Males

Parameter HR [95% CI] p-value
Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT 2.23 [1.68, 2.95] < 0.001
Birth year 0.985 [0.97, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 167 out of 1492 males with Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT died.

Mortality risk

Mortality risk for people of age

years, who have Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT.

N-year risk Females Males
1 0.224% 0.399%
5 1.109% 2.275%
10 2.602% 5.744%
15 5.149% 10.659%
20 8.668% 17.596%

Relationships between endpoints

↥

Index endpoint: Q17_OTHER_CONGEN_MALFO_UPPER_ALIME_TRACT – Other congenital malformations of upper alimentary tract

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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