Other congenital malformations of digestive system

Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM2

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q45 Cause of death: ICD-10 — Q45 2 out of 7 registries used, show all original rules.	85
4. Check minimum number of events None	85
5. Include endpoints None	85
6. Filter based on genotype QC (FinnGen only)	85

Control definitions (FinnGen only)

Control exclude: Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Q3[8-9]|Q4[0-5]
Name in latin: Aliae malformationes congenitae systematis digestorii

NAME	Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM2
CONTROL_EXCLUDE	Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM1
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q45
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q45
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other congenital malformations of digestive system based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	600	350	249
Only index persons	515	309	206
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	37.88	37.47	38.37
Only index persons	42.13	40.50	44.57

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	85	46	39
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	48.96	48.57	49.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
73: Matched controls
731

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Q45.38

ICD-10 Finland

Other congenital malformations of pancreas and pancreatic duct

+∞

25.5

Q45.8

ICD-10 Finland

Other specified congenital malformations of digestive system

+∞

16.2

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

8.5

15.8

122

XJD02

NOMESCO Finland

Peroral endoscopic ultrasonography

127.6

10.7

Q45.30

ICD-10 Finland

Ectopic pancreas

+∞

10.7

133

Kela drug reimbursment

Severe chronic pancreatic insufficiency

28.5

7.8

Q45.1

ICD-10 Finland

Annular pancreas

+∞

7.4

A09AA02

ATC

multienzymes (lipase, protease etc.)

22.8

7.4

JAH00

NOMESCO Finland

Laparotomy

19.0

7.0

K86.8

ICD-10 Finland

Other specified diseases of pancreas

76.2

6.5

Q45.0

ICD-10 Finland

Agenesis, aplasia and hypoplasia of pancreas

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3018095) Leukocytes [#/volume] in Urine

250

3.11

6.18

3.9

3.6

77.91

32.35

e6/l

0.43

184

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

328

3.23

6.15

7.7

8.6

1.21

mmol/l

0.04

284

(3025941) Bacteria identified in Stool by Culture

4.35

5.67

1.2

—

(3042936) Bacteria identified in Isolate by Culture

3.35

5.51

1.8

2.7

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

254

2.90

5.48

3.5

3.1

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

4.21

4.87

1.2

1.1

—

(3048689) Calprotectin [Mass/mass] in Stool

3.10

4.48

2.0

2.3

102.05

144.20

ug/g

0.47

(40768797) Stomach Pathology biopsy report

3.10

4.48

1.6

1.2

—

(3030467) Casts [#/volume] in Urine by Automated count

200

2.62

4.45

3.1

2.9

0.34

0.39

e6/l

0.11

151

(36304419) Bacteria [Presence] in Urine

199

2.52

4.08

3.4

2.8

—

(3002582) Erythrocytes [#/volume] in Urine

225

2.47

3.98

3.2

2.9

12.28

31.18

e6/l

0.63

175

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

118

2.58

3.55

2.8

0.59

0.68

e6/l

0.14

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

2.97

3.46

8.6

2.7

41.88

27.16

u/l

0.56

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

107

2.57

3.34

3.0

2.9

2.27

2.26

e6/l

0.00

(3044889) 12 lead EKG panel

467

2.49

3.31

3.9

3.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.03

3.25

1.5

1.4

—

(3015736) pH of Urine

287

2.20

3.16

3.0

3.5

—

(3037467) Urinalysis macro (dipstick) panel - Urine

474

2.41

3.09

6.0

4.1

—

(3023368) Bacteria identified in Blood by Culture

187

2.25

3.09

7.4

4.3

—

(40758558) Short blood count panel - Blood

173

2.24

2.99

7.4

7.6

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

168

2.21

2.86

3.3

3.9

—

(3000991) Gas panel - Venous blood

2.67

2.63

9.9

9.1

—

(3026782) Osmolality of Urine

143

2.18

2.56

2.4

605.33

549.92

mosm/kgh2o

0.27

121

(3034770) Mitochondria Ab [Titer] in Serum

4.66

2.53

1.6

1.1

—

(3026008) Bacteria identified in Urine by Culture

209

2.04

2.50

5.2

3.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

253

2.00

2.47

1.9

1.8

80.40

97.98

pmol/l

1.42

123

(3024891) Influenza virus A+B Ag [Presence] in Specimen

4.38

2.41

1.1

1.2

—

(3032080) INR in Blood by Coagulation assay

255

1.97

2.40

11.1

6.7

1.12

1.21

inr

0.45

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

318

1.88

2.13

5.1

4.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

145

2.02

2.11

5.0

2.4

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

3.71

2.10

2.4

5.1

274.43

196.35

—

(3044640) Blood type and Crossmatch panel - Blood

213

1.89

2.05

4.5

2.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

140

1.99

1.6

1.5

—

(42870588) Differential panel, method unspecified - Blood

215

1.87

1.98

8.1

6.0

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

3.37

1.92

1.7

1.5

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

118

2.03

1.92

1.7

1.8

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

3.04

1.91

1.9

2.1

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.16

1.91

1.6

1.5

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.50

1.78

1.2

1.3

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.83

1.77

5.3

27.1

—

(3035350) Ketones [Presence] in Urine by Test strip

350

1.76

1.77

4.3

3.7

0.00

estimate

—

(3002523) Influenza virus A Ag [Presence] in Specimen

4.01

1.74

1.2

1.1

—

(3003740) Influenza virus B Ag [Presence] in Specimen

4.01

1.74

1.2

1.1

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

641

2.18

1.63

21.2

12.0

90.87

84.58

ml/min/173m2

1.13

508

(3009261) Glucose [Presence] in Urine by Test strip

357

1.70

1.59

4.3

3.7

0.00

estimate

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.03

1.58

1.3

1.7

—

(1761868) Lipid panel - Serum or Plasma

252

0.51

1.57

3.5

2.6

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.01

1.54

1.3

1.8

—

(3021601) Nitrite [Presence] in Urine by Test strip

351

1.67

1.51

6.1

5.2

0.00

estimate

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

3.05

1.37

1.0

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

3.05

1.37

1.0

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

3.05

1.37

1.0

1.2

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.83

1.16

1.5

—

(36660697) Celiac disease serology panel - Serum

1.99

1.13

1.4

1.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.05

1.12

1.3

1.2

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.11

1.09

15.2

9.8

26.22

25.29

mmol/l

—

(3007164) IgA [Mass/volume] in Serum or Plasma

167

1.61

1.07

1.2

1.3

2.67

2.25

g/l

0.49

100

(3021589) Normoblasts [#/volume] in Blood

323

1.52

1.07

12.7

8.3

0.00

e9/l

0.00

263

(40760892) CBC W Ordered Manual Differential panel - Blood

164

1.55

0.92

7.7

6.1

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

114

1.61

0.87

1.3

55.48

25.39

iu/ml

—

(3029937) Albumin [Presence] in Urine by Test strip

194

1.49

0.85

4.5

3.8

0.00

estimate

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

260

1.44

0.82

3.0

3.4

30.26

32.61

ng/l

0.06

174

(3009508) Creatinine [Moles/volume] in Urine

196

1.47

0.80

3.6

3.0

8.10

7.72

mmol/l

0.13

173

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.78

0.78

1.6

1.5

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.74

0.77

5.0

4.2

69.11

70.86

ng/l

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.24

0.77

1.4

1.0

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

110

1.56

0.75

1.4

1.3

3.48

7.54

u/ml

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

1.77

0.72

1.7

2.6

—

(3003338) MCHC [Mass/volume]

630

1.50

0.70

33.5

17.3

332.42

333.53

g/l

0.56

630

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

165

1.45

0.69

2.5

2.1

2.87

1.01

mg/l

0.66

131

(3024354) Oxygen [Partial pressure] in Venous blood

1.69

0.68

3.4

4.4

4.22

4.83

kpa

—

(3020891) Body temperature

1.77

0.65

5.2

6.0

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

1.62

0.62

3.6

1.24

1.22

mmol/l

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

1.60

0.62

4.7

4.3

5.83

5.73

kpa

0.13

(3012544) pH of Venous blood

1.58

0.59

4.6

—

(40768793) Breast Pathology biopsy report

0.00

0.59

0.0

1.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

283

1.33

0.58

4.4

3.7

—

(3002256) Pathology report gross observation

1.54

0.58

1.6

1.2

—

(3022145) Colonoscopy Study observation

1.52

0.55

1.1

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.48

0.54

1.9

3.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.58

0.54

1.3

2.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.47

0.51

2.1

2.2

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

147

1.37

0.50

4.2

3.6

23.26

21.33

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.60

0.50

1.4

1.6

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.48

0.50

1.3

1.4

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.50

0.48

1.6

2.7

4.46

4.58

pmol/l

—

(3000494) Fungus identified in Specimen by Culture

1.47

0.45

1.5

1.8

—

(3022948) Iron [Moles/volume] in Serum or Plasma

105

1.40

0.44

2.6

2.2

12.87

12.94

umol/l

0.01

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

114

1.38

0.44

1.3

1.6

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.59

0.43

1.0

1.1

—

(3012516) Albumin [Mass/volume] in Urine

179

1.31

0.43

3.5

3.2

7.59

59.69

mg/l

2.34

125

(3007080) Epstein Barr virus nuclear IgG Ab [Units/volume] in Serum

0.00

0.41

0.0

1.6

—

173.00

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.6

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.4

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.41

0.0

1.5

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.41

0.0

1.8

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.4

—

(3022313) Gas panel - Capillary blood

1.50

0.41

7.4

5.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

199

1.29

0.41

4.3

3.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.41

0.39

1.0

1.9

—

(3020682) Albumin/Creatinine [Ratio] in Urine

191

1.28

0.38

4.6

3.9

1.79

8.10

mg/mmol

2.07

130

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.50

0.37

1.3

—

(3019060) Gas panel - Arterial blood

1.36

0.34

6.8

15.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

101

1.34

0.34

2.2

2.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

109

0.71

0.31

1.0

1.4

—

(40761535) Cells panel - Urine sediment

1.34

0.29

3.3

3.6

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

503

1.20

0.29

3.2

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.24

0.26

1.3

1.7

—

(3022217) INR in Platelet poor plasma by Coagulation assay

1.22

0.26

21.2

22.5

—

1.21

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

106

1.27

0.25

3.6

2.6

0.81

0.69

ug/l

—

(1002224) Polysomnography panel

1.37

0.24

1.2

1.0

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.26

0.23

3.0

3.3

0.90

1.41

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.0

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.21

0.0

2.3

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(44790047)

0.00

0.21

0.0

1.6

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.21

0.0

1.0

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.1

—

(44790048)

0.00

0.21

0.0

1.6

—

(44806118)

0.00

0.21

0.0

1.6

—

(44790049)

0.00

0.21

0.0

1.6

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.1

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.21

0.0

1.4

—

(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose

0.00

0.21

0.0

1.2

—

7.56

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3001405) CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood

0.00

0.21

0.0

1.8

—

688.00

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.2

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.24

0.20

1.2

1.0

—

(21494755) Public health laboratory ask at order entry panel

1.14

0.16

1.4

1.3

—

(40768804) Tissue Pathology biopsy report

267

1.13

0.15

1.9

2.0

—

(40761511) CBC panel - Blood by Automated count

752

1.24

0.14

21.8

11.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

151

1.16

0.14

1.6

1.9

—

(3013512) EKG study

183

1.12

0.11

3.7

3.4

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

1.07

0.09

8.4

4.9

-0.24

1.04

mmol/l

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.07

0.09

1.2

2.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.10

0.08

1.7

2.0

—

(3009542) Hematocrit [Volume Fraction] of Blood

664

1.04

0.00

29.8

13.7

39.87

40.20

0.12

506

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

6.4

—

0.53

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

1.1

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

8.0

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

2.0

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(4146454)

0.00

0.0

2.2

—

(3000492) Spirometry study

0.94

0.00

1.6

1.5

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.6

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.1

—

(4211845)

0.00

0.0

1.4

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

0.0

1.6

—

(3011648) Oxygen content in Venous blood

0.00

0.0

1.0

—

9.63

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3005082) Progesterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

46.40

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.2

—

136.92

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.0

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.2

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.0

1.6

—

(4027681)

0.00

0.0

1.3

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.01

0.00

10.5

7.7

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.4

—

89.11

—

(3034426) Prothrombin time (PT)

0.00

0.0

1.0

—

(4035726)

1.02

0.00

1.3

1.5

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.0

5.8

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.0

1.0

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.1

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(40761536) Microorganisms panel - Urine sediment

0.92

0.00

11.2

3.3

—

(43534046) Estradiol (E2) [Moles/volume] in Serum or Plasma by High sensitivity method

0.00

0.0

3.0

—

0.16

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

0.0

2.4

—

(3003694) ABO and Rh group [Type] in Blood

207

1.02

0.00

1.4

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM2 and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM2.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: Q17_OTHER_CONGEN_MALFO_DIGES_SYSTEM2 – Other congenital malformations of digestive system

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other congenital malformations of digestive system

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints