Distal bite

K11_DISTAL_BITE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 K07.20
  • Hospital discharge: ICD-10 K07.20
  • Cause of death: ICD-10 K07.20

3 out of 7 registries used, show all original rules.

1590

4. Check minimum number of events

None

1590

5. Include endpoints

None

1590

6. Filter based on genotype QC (FinnGen only)

1515

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF10

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 68300 33824 34461
Only index persons 55449 27655 27794
Unadjusted period prevalence (%)
Whole population 0.97 0.97 0.96
Only index persons 1.04 1.02 1.06
Median age at first event (years)
Whole population 10.38 10.43 10.32
Only index persons 11.12 11.17 11.07

-FinnGen-

Key figures

All Female Male
Number of individuals 1515 1048 467
Unadjusted period prevalence (%) 0.32 0.37 0.21
Median age at first event (years) 16.37 17.40 14.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1590
Matched controls
15795
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
+∞
307.7
1590
*
SBB10
NOMESCO Finland
Dental impressions
7.5
307.7
992
2867
K07.23
ICD-10 Finland
Deep bite
13.4
307.7
795
1100
EDC10
NOMESCO Finland
Sagittal osteotomy of ramus of mandible
78.2
307.7
206
30
K07.22
ICD-10 Finland
Anomalies of dental arch relationship
18.3
307.7
322
216
K07.13
ICD-10 Finland
Retrognaty, mandibular
22.8
307.7
467
283
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
7.1
279.7
540
1060
SJD10
NOMESCO Finland
Placement of orthodontic arch wire
6.4
276.9
653
1555
SJD00
NOMESCO Finland
Removal and/or reactivation of orthodontic arch wire
6.4
276.0
641
1504
EB1MA
NOMESCO Finland
Cephalometry with X-ray
6.2
251.3
576
1322
SJD20
NOMESCO Finland
Placement of modified orthodontic arch wire
6.5
244.0
511
1074
SJB60
NOMESCO Finland
Adjustment and grinding of removable appliance
6.8
243.2
479
948
SJB00
NOMESCO Finland
Fitting of removable appliance incl. patient instructions
5.7
235.4
618
1592
SJC10
NOMESCO Finland
Orthodontic band in one tooth
6.0
222.9
510
1156
SJC50
NOMESCO Finland
Removal of fixed orthodontic appliance with at least 7 brackets
5.7
219.5
541
1309
SJC03
NOMESCO Finland
Positioning and fixed attachment of brackets, extensive
5.9
206.5
467
1041
SJD30
NOMESCO Finland
Demanding placement of orthodontic arch wire
6.5
194.6
378
727
SAA04
NOMESCO Finland
Special examination of mouth
5.2
191.6
529
1394
SJX10
NOMESCO Finland
Orthodontic treatment/control appointment, short
4.3
173.0
663
2231
SXC05
NOMESCO Finland
Other oral or dental procedure
4.4
172.5
637
2085
SJB10
NOMESCO Finland
Fitting of removable appliance incl. patient instructions, demanding
6.7
159.1
284
497
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
4.2
137.2
479
1473
SJC01
NOMESCO Finland
Positioning and fixed attachment of single bracket (Bracket with fixed attachment)
4.1
127.2
449
1384
SJX11
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment, restricted
3.7
125.4
562
2037
SJX21
NOMESCO Finland
Therapeutic intervention or check-up related to orthodontic treatment
3.9
118.1
452
1467
SJC02
NOMESCO Finland
Positioning and fixed attachment of brackets
4.5
113.5
322
838
SJD40
NOMESCO Finland
Placement of prefabricated palatal or lingual arch
3.7
110.3
453
1534
K07.24
ICD-10 Finland
Open bite
7.1
108.1
174
270
OIKH, ,
NOMESCO Finland
3.9
104.6
385
1207
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
3.8
104.5
389
1229
SJD50
NOMESCO Finland
Placement of prefabricated palatal or lingual arch, dentist-made
6.6
100.4
173
288
SJC00
NOMESCO Finland
Bondable bracket or other fixed attachement
31.5
97.4
64
21
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
5.5
96.8
202
404
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.0
93.1
1028
6015
OIKK, ,
NOMESCO Finland
3.3
92.9
461
1738
SAA03
NOMESCO Finland
Extended examination of mouth
3.3
90.2
1217
7886
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
6.4
87.2
154
262
SJX20
NOMESCO Finland
Orthodontic treatment/control appointment
3.5
87.0
376
1297
K07.60
ICD-10 Finland
Snapping jaw
4.5
80.8
219
543
SAC02
NOMESCO Finland
Separate planning of oral and dental treatment, demanding
3.8
79.1
281
848
SAC01
NOMESCO Finland
Separate planning of oral and dental treatment, standard
3.4
76.9
326
1104
SHA04
NOMESCO Finland
Stomatognathic treatment, very demanding
12.1
75.5
77
66
EBB10
NOMESCO Finland
Insertion of dental implant
13.0
69.8
68
54
SJA04
NOMESCO Finland
Very demanding workplan for orthodontic treatment
33.7
66.7
43
13
K07.27
ICD-10 Finland
Anomalies of dental arch relationship
4.8
64.8
157
354
SAC03
NOMESCO Finland
Separate planning of oral and dental treatment, very demanding
7.0
62.3
98
147
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.0
61.7
337
1312
SJB30
NOMESCO Finland
Extraoral traction arrangements and operation instruction, removable appliance
4.5
61.2
162
392
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
4.3
59.2
167
424
SJC40
NOMESCO Finland
Removal of fixed orthodontic appliance with at most 6 brackets
2.8
58.6
356
1464
EEC05
NOMESCO Finland
Le Fort I osteotomy
27.1
57.9
40
15
WZC00
NOMESCO Finland
Treatment plan or consultation
2.3
56.8
870
5443
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
3.3
54.5
238
810
EBB15
NOMESCO Finland
Insertion of dental implant abutment
17.0
53.7
45
27
K07.12
ICD-10 Finland
Prognathism (mandibular)(maxillary)
13.7
45.7
43
32
K07.10
ICD-10 Finland
Asymmetry of jaw
11.7
45.4
47
41
SPC20
NOMESCO Finland
Implant borne crown
16.8
45.1
38
23
WZA90
NOMESCO Finland
Other medical or dental certificate
2.1
40.6
619
3722
EFB40
NOMESCO Finland
Removal of internal or external fixation device from facial bones
15.2
37.2
33
22
OIKAL, ,
NOMESCO Finland
2.9
33.8
176
656
K07.04
ICD-10 Finland
Macrognathism (mandibular)(maxillary)
32.1
31.3
41
13
SJC20
NOMESCO Finland
Extraoral traction appliance arrangement incl. patient instructions
4.1
31.1
89
227
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
2.4
30.9
241
1094
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.8
27.8
818
5880
SAA02
NOMESCO Finland
Basic examination of mouth
2.5
27.5
1436
12417
SJX00
NOMESCO Finland
Reparation of orthodontic appliance by dentist
4.2
27.2
75
186
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
27.0
517
3261
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
7.3
26.6
39
54
SXC03
NOMESCO Finland
Other oral or dental procedure
8.8
26.1
33
38
Z01.2
ICD-10 Finland
Dental examination
1.8
26.1
1031
8009
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prosthodontic work
4.8
25.8
59
126
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
7.7
24.9
35
46
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
4.9
24.2
54
113
SJA01
NOMESCO Finland
Assesment of orthodontic treatment need
7.4
24.0
35
48
SXB00
NOMESCO Finland
Removal of sutures from oral mucosa
2.7
22.6
128
496
SAALT, ,
NOMESCO Finland
2.9
22.0
108
388
OIKKK, ,
NOMESCO Finland
5.1
21.3
45
90
K07.1
ICD-10 Finland
Anomalies of jaw-cranial base relationship
25.7
20.4
28
11
SAA01
NOMESCO Finland
Simple examination of mouth
1.9
19.8
1303
11205
G50.1
ICD-10 Finland
Atypical facial pain
6.1
19.7
34
56
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
5.8
19.2
35
61
EB1S1
NOMESCO Finland
Photography of teeth
4.8
18.6
42
89
K07.69
ICD-10 Finland
Dislocation of the jaw joint UNS
4.6
18.6
44
97
OIKJA, ,
NOMESCO Finland
3.4
18.2
66
198
SDA03
NOMESCO Finland
Periodontal treatment
1.6
17.9
566
4007
K07.18
ICD-10 Finland
Another anomaly in the relationship between jaw and skull base
18.2
17.7
27
15
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
5.3
17.4
35
67
ECB40
NOMESCO Finland
Surgical treatment of fracture of alveolus
7.8
17.3
24
31
K00.00
ICD-10 Finland
Hypodontia
2.7
17.1
94
359
OIKVA, ,
NOMESCO Finland
2.2
16.7
153
736
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
12.7
16.6
29
23
K07.33
ICD-10 Finland
Crowding of tooth or teeth
5.3
15.5
31
59
-1, ,
NOMESCO Finland
1.5
15.3
853
6795
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.5
15.2
639
4785
SJF01
NOMESCO Finland
Assessment of need for orthodontic treatment
1.8
14.6
246
1460
EDC30
NOMESCO Finland
Genioplasty
+∞
14.6
14
*
EMAK, ,
NOMESCO Finland
3.0
14.3
65
224
OIKPU, ,
NOMESCO Finland
4.0
14.3
41
105
EB1WA, ,
NOMESCO Finland
6.0
14.2
25
42
D19
ICPC
Teeth/gum symptom/complaint
1.5
14.0
547
4016
K07.61
ICD-10 Finland
Cracking jaw joint
2.8
13.9
68
244
EB1AI
NOMESCO Finland
Cone beam imaging of teeth and jaws (one quarter)
3.5
13.9
48
140
OIKRE, ,
NOMESCO Finland
3.1
13.8
58
191
G47.3
ICD-10 Finland
Sleep apnoea
1.9
13.8
192
1074
SJA03
NOMESCO Finland
Demanding workplan for orthodontic treatment
10.5
13.7
26
25
K03.00
ICD-10 Finland
Approximal wear
2.1
13.4
134
667
WYA10
NOMESCO Finland
Emergency care or similar visit
2.0
13.4
160
850
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.8
13.0
228
1368
SXC02
NOMESCO Finland
Other oral or dental procedure, restricted
3.2
12.9
50
157
K03.66
ICD-10 Finland
Tooth plaque
1.7
12.9
241
1471
M79.1
ICD-10 Finland
Myalgia
1.8
12.6
208
1225
OIKNV, ,
NOMESCO Finland
3.7
12.5
39
106
SPA20
NOMESCO Finland
Selection and insertion of implant abutment
20.1
12.4
18
9
K07.29
ICD-10 Finland
Anomaly in the relationship between the tooth arches UNS
37.6
12.2
15
*
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
5.5
12.0
23
42
SPA41
NOMESCO Finland
Precision impression for fixed dental prosthesis
4.2
11.7
31
75
K07.26
ICD-10 Finland
Anomalies of dental arch relationship
5.1
11.6
24
47
Z96.5
ICD-10 Finland
Presence of tooth-root and mandibular implants
18.9
11.5
17
9
EG1CG
NOMESCO Finland
Extensive MRI examination of mandibular joint with high intensity magnet
5.4
11.3
22
41
EBA10
NOMESCO Finland
Operative extraction of tooth
1.6
11.2
312
2107
K05.30
ICD-10 Finland
Periodontitis complex
2.0
11.0
121
624
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.5
10.9
362
2540
K07.21
ICD-10 Finland
Anomalies of dental arch relationship
4.0
10.7
30
76
K07.35
ICD-10 Finland
Impacted or embedded teeth with abnormal position of such teeth or adjacent teeth
2.7
10.7
55
204
SPAT1312
SPAT
General health counselling
1.4
10.6
680
5424
F45.8
ICD-10 Finland
Other somatoform disorders
1.9
10.4
130
700
SPC10
NOMESCO Finland
Standard dental crown
4.8
10.4
23
48
K07.62
ICD-10 Finland
Habitual dislocation of the jaw joint
4.6
10.4
24
52
EG1AA
NOMESCO Finland
Mandibular joint X-ray examination
5.4
10.3
20
37
EBA12
NOMESCO Finland
Demanding operative extraction of tooth
2.2
10.2
87
407
OIKAK, ,
NOMESCO Finland
4.6
9.9
23
50
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.5
9.5
333
2356
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
3.4
9.5
34
102
QA9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head or neck, unspecified
10.7
8.8
16
15
K07.14
ICD-10 Finland
Retrognaty, maxillary
3.4
8.7
31
93
SCD01
NOMESCO Finland
Removal of biofilm and supragingival calculus, short
2.6
8.7
49
191
K07.19
ICD-10 Finland
Anomalies in the relationship between jaw and skull base UNS
14.0
8.7
14
10
OIKON, ,
NOMESCO Finland
2.8
8.6
43
157
SFA10
NOMESCO Finland
One-surface restoration
1.4
8.6
952
8215
K07.4
ICD-10 Finland
Malocclusion, unspecified
2.6
8.6
50
198
K08.2
ICD-10 Finland
Atrophy of edentulous alveolar ridge
11.6
8.5
15
13
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.3
8.5
65
292
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
8.2
740
6161
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
7.9
133
785
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.0
7.9
80
402
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
7.9
1166
10468
G50.8
ICD-10 Finland
Other disorders of trigeminal nerve
13.0
7.8
13
10
EAB10
NOMESCO Finland
Excision and repair of frenum of lip
4.4
7.8
19
43
SPB10
NOMESCO Finland
Manufacture of a temporary crown to tooth at the dental office
7.4
7.6
17
23
SAE02, ,
NOMESCO Finland
3.4
7.6
27
81
SCA02
NOMESCO Finland
Preventive oral health care
1.4
7.6
466
3643
SPB20
NOMESCO Finland
Temporary bridge
11.8
7.5
13
11
K06.00
ICD-10 Finland
Local gingivore traction
2.9
7.5
33
113
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
2.6
7.5
41
158
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
79.9
7.4
8
*
SDA12
NOMESCO Finland
Treatment of complicated periodontal disease
3.9
7.4
21
54
EB1BD
NOMESCO Finland
Extensive cone beam CT of teeth and jaws (two quarters)
13.3
7.4
12
9
K05.31
ICD-10 Finland
Periodontitis pronounced
2.0
7.3
79
407
EB1TW
NOMESCO Finland
3D modelling of dentition
6.8
7.3
17
25
OIKKE, ,
NOMESCO Finland
3.8
7.2
21
55
EDW99
NOMESCO Finland
Other operation on mandible
20.0
7.1
10
5
K07.2
ICD-10 Finland
Anomalies of dental arch relationship
20.0
7.1
10
5
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
2.4
7.0
46
193
J02AC01
ATC
fluconazole; systemic
1.4
7.0
412
3188
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
4.1
7.0
19
47
OIKTA, ,
NOMESCO Finland
3.0
7.0
29
96
OIKLI, ,
NOMESCO Finland
4.2
6.9
18
43
TEW99
NOMESCO Finland
Other minor procedure in surgery of teeth, jaws, mouth and pharynx
2.1
6.9
62
297
SJC04, ,
NOMESCO Finland
3.2
6.9
27
86
K03.1
ICD-10 Finland
Abrasion of teeth
3.3
6.9
25
76
ECA70
NOMESCO Finland
Regenerative periodontal surgery or gingival graft
10.9
6.8
12
11
EBA00
NOMESCO Finland
Extraction of tooth
1.3
6.8
676
5664
ECA55
NOMESCO Finland
Complicated periodontal flap surgery
9.3
6.8
13
14
K07.68
ICD-10 Finland
Other disorders of the jaw joint
3.8
6.7
20
53
SPC25
NOMESCO Finland
Other demanding attachment of prosthodontic crown
22.5
6.7
9
*
Z97.2
ICD-10 Finland
Presence of dental prosthetic device (complete)(partial)
3.5
6.6
22
63
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
3.9
6.6
19
49
127
Kela drug reimbursment
Transplant complication
2.7
6.5
34
128
K07
ICD-10 Finland
Dentofacial anomalies [including malocclusion]
3.5
6.4
21
60
K07.55
ICD-10 Finland
Malocclusion caused by tongue, lip and finger habits
4.1
6.3
17
42
SPAT1324
SPAT
Screening procedure
1.5
6.3
198
1365
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
2.8
6.3
30
108
SPE05
NOMESCO Finland
Demanding partial denture with metal framework
18.0
6.2
9
5
XX2XX, ,
NOMESCO Finland
+∞
6.2
6
*
K08.0
ICD-10 Finland
Exfoliation of teeth due to systemic causes
+∞
6.2
6
*
R06.5
ICD-10 Finland
Mouth breathing
1.7
6.2
113
683
YEA05
NOMESCO Finland
Excision of gingival or connective tissue for transplantation
26.6
6.2
8
*
SCA01
NOMESCO Finland
Preventive oral health care, short
1.3
6.2
973
8633
SPC08
NOMESCO Finland
Implant crown
7.6
6.1
13
17
K08.80
ICD-10 Finland
Toothache NOS
1.6
6.1
125
782
SXC06
NOMESCO Finland
Clinical work to produce sleep apnoea splint
10.0
6.0
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
373
2877
1.38
6.42
4.7
3.2
0.00
0.01
estimate
1.08
115
1041
348
2663
1.38
6.27
3.0
2.7
37.20
31.06
ng/l
0.13
176
1242
110
673
1.67
5.81
3.9
3.2
—
—
—
0
0
273
2070
1.37
5.14
3.3
2.8
—
—
—
0
0
944
8481
1.26
4.78
4.8
3.9
8.16
8.64
mm/h
0.89
880
7884
205
1507
1.40
4.63
4.5
3.7
833.68
704.25
ng/l
0.23
159
1232
740
6490
1.25
4.53
3.4
2.9
70.14
70.76
ug/l
0.02
698
6125
123
823
1.53
4.52
4.4
4.1
0.41
0.57
%
0.57
39
247
39
187
2.10
4.46
8.4
3.7
—
—
—
0
0
210
1561
1.39
4.45
1.4
1.5
80588678.88
28561426.24
pmol/l
0.42
170
1369
207
1555
1.37
4.11
10.4
6.9
0.81
0.82
mmol/l
0.25
197
1487
22
86
2.56
4.00
2.3
2.1
—
—
—
0
0
59
344
1.73
3.81
1.2
1.2
—
—
—
0
0
70
428
1.65
3.80
1.5
1.2
0.44
1.38
u/ml
—
9
22
32
152
2.11
3.79
9.6
4.9
—
—
—
0
0
296
2374
1.29
3.74
2.5
2.2
180.99
225.72
u/l
0.71
279
2267
327
2661
1.28
3.69
4.0
2.9
1.01
1.02
kg/l
0.87
47
368
36
183
1.98
3.58
3.7
2.7
17.31
17.23
%
0.05
23
105
44
241
1.84
3.52
5.8
4.0
—
—
—
0
0
356
2943
1.26
3.51
2.8
2.5
60.85
57.46
u/l
0.35
330
2749
82
535
1.55
3.44
6.4
7.0
133.44
131.12
g/l
0.49
77
517
116
814
1.45
3.43
4.8
4.6
0.00
0.07
%
1.41
31
211
119
840
1.44
3.41
4.7
4.6
0.06
0.10
%
0.25
34
239
232
1839
1.30
3.20
1.3
1.2
15.11
24.48
iu/ml
1.87
69
531
71
457
1.57
3.18
3.7
2.5
0.20
0.19
e6/l
0.04
65
442
123
887
1.41
3.15
4.7
4.5
0.46
0.79
%
0.86
37
288
546
4785
1.20
3.02
3.0
2.7
—
—
—
0
0
50
300
1.68
2.98
2.1
1.7
—
—
—
0
0
145
1086
1.36
2.97
1.5
1.6
1255.89
1165.03
nmol/l
0.60
100
855
75
502
1.51
2.85
1.6
2.1
5.64
7.96
ug/l
0.80
63
435
219
1763
1.27
2.69
1.2
1.2
3.09
10.19
u/ml
2.31
85
635
151
1161
1.32
2.62
1.3
1.3
—
—
—
0
0
704
6370
1.18
2.61
8.9
7.4
—
—
—
0
0
617
5527
1.18
2.57
5.5
4.3
0.00
0.00
estimate
0.50
122
1067
618
5541
1.18
2.54
4.2
3.0
0.00
0.00
estimate
0.50
120
1083
1324
12659
1.23
2.51
11.8
10.0
20.61
21.18
mg/l
0.23
976
8961
129
976
1.34
2.51
1.5
1.4
—
—
—
0
0
144
1825
0.76
2.50
1.2
1.2
—
—
—
0
0
620
5566
1.17
2.50
4.3
3.1
0.00
0.00
estimate
0.50
121
1042
391
3376
1.20
2.48
7.0
7.1
1.13
1.10
inr
0.39
126
1081
44
270
1.64
2.46
3.6
3.9
48.68
54.00
%
2.23
44
270
63
421
1.51
2.45
4.4
7.4
0.72
0.66
%
0.59
63
421
43
264
1.64
2.40
3.0
3.7
3.01
3.76
e9/l
2.48
43
264
6
12
4.98
2.39
4.0
3.3
4.47
4.13
mmol/l
—
6
12
406
3530
1.19
2.38
2.7
2.2
—
—
—
0
0
223
1830
1.24
2.33
3.8
3.1
3257.00
3626.16
umol/l
0.06
205
1663
111
832
1.35
2.32
2.6
3.2
4.83
4.84
pmol/l
0.02
103
758
738
6757
1.16
2.24
8.5
7.0
0.54
0.54
e9/l
0.01
673
5819
25
135
1.85
2.18
1.1
1.2
47.41
32.66
mg/l
0.48
20
108
20
100
2.00
2.17
2.4
1.9
—
—
—
0
0
209
1718
1.24
2.16
1.5
1.5
432.00
539.57
titre
0.56
35
323
96
712
1.36
2.16
1.2
1.2
—
—
—
0
0
35
210
1.67
2.16
10.8
4.4
1.60
2.03
mmol/l
0.57
20
125
12
48
2.49
2.16
3.8
3.0
—
—
—
0
0
521
4658
1.17
2.15
3.7
2.9
5.95
6.01
ph
0.18
40
443
737
6763
1.15
2.14
8.5
7.0
0.04
0.04
e9/l
0.10
671
5822
41
257
1.60
2.14
7.2
6.6
—
—
—
0
0
758
6983
1.15
2.06
8.4
6.9
2.05
2.07
e9/l
0.30
695
6185
109
833
1.32
2.03
2.4
2.2
10.80
9.79
nmol/l
0.54
98
758
151
1209
1.27
1.98
6.8
5.4
1.44
1.52
%
0.43
140
1115
55
376
1.47
1.97
2.9
2.2
—
—
—
0
0
358
3129
1.18
1.95
3.7
2.6
—
—
—
0
0
189
1556
1.23
1.94
3.8
3.8
29.65
30.10
s
0.61
181
1528
408
3612
1.16
1.89
2.0
1.8
—
—
—
0
0
539
4873
1.15
1.87
3.6
2.7
74.55
69.91
nmol/l
3.51
500
4541
755
6984
1.14
1.87
9.0
7.4
0.18
0.19
e9/l
0.71
689
6134
526
4748
1.15
1.87
6.2
5.9
10.95
11.09
umol/l
0.07
491
4426
662
6074
1.14
1.85
6.2
5.1
6.10
6.24
mmol/l
0.98
607
5599
69
499
1.39
1.84
9.2
6.2
0.22
0.43
g/l
1.29
49
314
64
459
1.40
1.80
2.7
1.8
—
—
—
0
0
8
29
2.75
1.77
6.0
2.2
—
—
—
0
0
13
60
2.16
1.75
1.6
1.4
1.03
0.98
g/l
0.12
13
60
109
853
1.29
1.74
4.4
4.0
58.59
68.48
e9/l
2.48
83
592
785
7305
1.13
1.73
4.0
3.3
35.82
33.86
u/l
0.15
737
6975
358
3159
1.16
1.72
2.8
2.3
—
—
—
0
0
174
1443
1.22
1.69
1.6
1.8
—
—
—
0
0
19
103
1.84
1.68
2.3
1.4
—
—
—
0
0
15
75
2.00
1.67
1.6
2.4
—
—
—
0
0
151
1236
1.24
1.66
1.3
1.4
186.49
312.15
u/ml
1.88
146
1133
210
1779
1.20
1.65
12.9
8.0
1.21
1.20
mmol/l
0.17
197
1692
27
164
1.65
1.65
4.6
3.1
—
—
—
0
0
10
41
2.43
1.63
2.9
2.5
1.32
1.15
umol/l
—
10
41
176
1467
1.22
1.63
1.6
1.8
—
—
—
0
0
15
76
1.97
1.61
1.6
2.4
106.27
105.75
mmol/l
0.19
15
76
175
1461
1.21
1.60
1.6
1.8
—
—
—
0
0
28
174
1.61
1.57
1.7
1.3
—
—
—
0
0
336
2974
1.16
1.55
4.1
3.6
8.13
8.78
mmol/l
1.31
301
2718
263
2286
1.17
1.54
2.6
2.5
0.92
1.08
mg/l
0.46
188
1616
166
1385
1.21
1.54
3.0
2.4
311.01
370.56
nmol/l
4.12
153
1305
50
355
1.41
1.53
1.2
1.1
—
—
—
0
0
15
78
1.92
1.51
1.6
2.4
4.07
3.96
mmol/l
0.67
15
78
12
58
2.06
1.47
3.8
3.2
—
—
—
0
0
12
59
2.03
1.41
4.1
4.6
3.77
3.72
%
—
6
24
161
1353
1.20
1.40
1.6
1.8
—
—
—
0
0
939
8902
1.12
1.39
3.6
3.1
1.16
1.19
mmol/l
0.75
878
8391
18
103
1.74
1.38
1.1
1.2
—
—
—
0
0
298
2640
1.15
1.36
4.1
3.0
—
—
—
0
0
17
96
1.77
1.36
1.1
1.2
—
—
—
0
0
9
41
2.19
1.36
1.1
1.1
—
—
—
0
0
9
41
2.19
1.36
1.1
1.1
—
—
—
0
0
12
60
1.99
1.36
1.3
1.2
—
—
—
0
0
171
1450
1.19
1.36
1.6
1.8
—
—
—
0
0
697
6512
1.11
1.33
8.8
7.2
8.22
8.16
%
0.23
665
6152
19
112
1.69
1.32
6.5
4.3
—
—
—
0
0
78
977
0.78
1.32
1.8
2.3
46.15
31.20
u/l
0.88
68
821
710
6646
1.11
1.30
8.3
6.8
53.04
53.35
%
0.30
679
6309
28
184
1.52
1.29
3.4
2.7
—
—
—
0
0
795
7490
1.11
1.28
10.1
9.0
3.64
3.74
e9/l
0.65
730
6411
1047
10009
1.11
1.27
4.0
3.7
14.47
14.36
pmol/l
0.84
939
9073
6
25
2.39
1.23
1.0
1.3
—
—
—
0
0
16
92
1.74
1.22
1.4
1.2
—
—
—
0
0
76
599
1.27
1.22
2.8
1.6
206.05
193.20
u/ml
0.11
42
299
193
1671
1.17
1.21
3.7
2.5
14.58
14.32
umol/l
0.19
180
1583
689
6458
1.11
1.20
8.7
7.1
2.97
2.92
%
0.22
655
6106
719
6755
1.10
1.20
8.5
7.0
32.26
32.10
%
0.16
687
6415
10
49
2.03
1.20
1.8
2.6
—
—
—
0
0
10
49
2.03
1.20
1.6
1.2
—
—
—
0
0
164
1880
0.85
1.18
4.0
3.0
3.69
3.93
e6/l
0.10
104
987
31
213
1.45
1.17
1.2
1.1
4.50
5.91
iu/ml
—
5
43
1216
11743
1.12
1.17
13.2
10.6
3.91
3.90
mmol/l
1.08
1173
11353
14
79
1.77
1.14
1.1
1.1
1.08
1.06
ratio
—
7
34
278
2483
1.14
1.14
3.1
2.5
—
—
—
0
0
1345
13078
1.14
1.12
10.2
8.5
—
—
—
0
0
19
118
1.61
1.12
1.7
1.7
—
—
—
0
0
17
103
1.65
1.10
1.9
1.6
31.59
32.42
pg
0.37
17
103
1146
11710
0.90
1.10
14.6
12.8
13.93
13.76
%
0.62
1122
11446
30
208
1.44
1.10
1.3
1.2
—
—
—
0
0
103
852
1.21
1.10
2.4
2.2
27.81
16.79
au/ml
—
8
59
7
31
2.25
1.10
1.1
2.2
—
—
—
0
0
117
981
1.20
1.09
4.3
3.4
—
—
—
0
0
42
310
1.36
1.09
1.5
1.2
3.65
21.14
u/ml
—
6
44
173
1501
1.16
1.08
3.8
2.5
2.54
2.54
g/l
0.02
161
1401
8
41
1.94
1.08
1.1
1.1
—
—
—
0
0
77
620
1.25
1.06
4.1
4.6
22.21
22.17
s
0.02
71
568
160
1383
1.17
1.05
4.1
2.6
23.46
22.97
%
0.16
146
1240
341
3101
1.12
1.05
3.0
2.7
2.77
2.70
mg/l
0.24
295
2737
980
9385
1.10
1.04
3.9
3.5
2.78
2.77
mmol/l
0.06
910
8841
28
194
1.44
1.04
4.5
3.4
0.16
0.18
e9/l
0.24
28
155
22
145
1.51
1.03
5.2
3.3
28.68
23.94
umol/l
0.55
22
145
9
46
1.95
1.03
2.7
1.6
—
—
—
0
0
662
6231
1.09
1.02
8.8
7.2
0.65
0.65
%
0.07
630
5873
5
22
2.26
1.02
1.0
1.0
—
—
—
0
0
5
22
2.26
1.02
1.0
1.0
—
—
—
0
0
5
22
2.26
1.02
1.0
1.0
—
—
—
0
0
24
162
1.48
1.01
4.6
4.1
—
—
—
0
0
344
3136
1.11
1.01
3.2
2.5
—
—
—
0
0
21
138
1.52
1.00
6.0
3.8
—
—
—
0
0
31
221
1.40
1.00
4.2
3.4
1.01
1.31
e9/l
1.58
31
182
28
196
1.43
0.99
4.5
3.4
390.50
517.37
e6/l
1.33
28
155
15
91
1.64
0.98
2.1
1.6
—
—
—
0
0
1210
11720
1.11
0.98
13.2
10.5
139.63
139.62
mmol/l
0.08
1168
11377
236
2109
1.13
0.98
3.7
4.0
—
—
—
0
0
77
627
1.23
0.98
2.6
2.2
—
—
—
0
0
9
50
1.79
0.96
2.3
2.5
—
—
—
0
0
78
639
1.22
0.94
9.5
3.5
1.23
1.23
mmol/l
0.35
71
565
14
85
1.64
0.92
1.4
1.3
—
—
—
0
0
46
355
1.30
0.91
1.1
1.1
—
—
—
0
0
12
194
0.61
0.91
1.1
1.2
—
—
—
0
0
41
312
1.31
0.90
3.0
2.7
212.02
287.42
ug/l
0.94
35
278
56
445
1.26
0.89
1.1
1.1
17.00
16.18
au/ml
—
5
26
965
9272
1.09
0.88
3.8
3.3
1.49
1.46
mmol/l
0.97
896
8748
977
9393
1.09
0.88
3.9
3.4
4.64
4.60
mmol/l
0.68
920
8918
62
500
1.24
0.88
3.4
2.6
66.33
67.02
g/l
0.29
57
470
35
263
1.33
0.85
1.3
1.5
25.94
15.80
u/l
0.91
25
230
153
1344
1.14
0.84
2.1
1.5
—
—
—
0
0
546
5136
1.09
0.83
11.2
7.7
1.23
1.22
mmol/l
1.80
479
4551
103
879
1.18
0.83
2.1
2.0
6.54
7.08
u/l
0.26
85
653
39
300
1.30
0.81
1.3
1.2
—
—
—
0
0
156
1377
1.14
0.81
15.9
5.7
5.03
5.08
kpa
0.59
150
1323
288
2635
1.10
0.81
5.5
3.5
7.39
7.39
ph
0.13
57
476
11
65
1.69
0.80
1.0
1.1
1434.64
1439.54
miu/ml
0.01
11
65
417
3885
1.09
0.80
1.9
2.0
—
—
—
0
0
77
644
1.20
0.79
1.1
1.1
—
—
—
0
0
45
355
1.27
0.78
1.1
1.1
—
—
—
0
0
6
33
1.81
0.78
7.5
4.7
—
—
—
0
0
155
1373
1.13
0.77
16.0
5.7
7.39
7.41
ph
1.40
13
89
20
139
1.43
0.77
1.0
1.0
—
—
—
0
0
121
1056
1.15
0.75
15.5
6.1
9.98
9.75
kpa
0.93
115
1018
83
703
1.18
0.75
3.9
3.9
—
—
—
0
0
24
174
1.38
0.74
4.3
3.4
136.67
256.12
e6/l
2.12
24
121
99
1130
0.86
0.73
1.5
1.4
—
—
—
0
0
40
498
0.79
0.73
2.6
3.9
4.06
16.51
ug/l
0.69
25
363
8
135
0.59
0.73
1.3
1.1
—
—
—
0
0
50
404
1.24
0.73
3.4
2.5
—
—
—
0
0
7
39
1.79
0.72
1.4
1.3
139.00
151.60
nmol/l
—
7
39
1167
11344
1.08
0.72
4.6
4.2
1.87
1.97
mu/l
0.49
1092
10674
123
1079
1.14
0.72
1.2
1.2
—
—
—
0
0
132
1165
1.14
0.71
1.8
1.6
—
—
—
0
0
20
273
0.72
0.70
4.9
3.0
31.95
32.67
umol/l
0.06
20
253
10
60
1.66
0.70
2.0
2.4
28.14
16.78
mg/l
—
5
45
11
68
1.61
0.70
1.3
1.1
—
—
—
0
0
7
41
1.70
0.69
2.3
3.4
—
—
—
0
0
36
282
1.27
0.68
1.4
1.4
353.76
328.61
ug/g
0.30
14
140
813
7810
1.07
0.68
7.0
6.1
89.24
88.93
u/l
0.05
767
7363
5
27
1.84
0.68
1.0
1.5
—
10.13
%
—
0
8
254
2334
1.10
0.67
4.4
2.7
7.47
7.91
e6/l
0.18
232
2085
864
8320
1.07
0.67
4.3
3.9
36.75
37.49
mmol/mol
1.59
804
7838
11
69
1.59
0.67
1.1
1.0
—
—
—
0
0
44
355
1.24
0.66
3.6
3.5
6.37
7.38
umol/l
0.34
32
287
117
1030
1.14
0.66
2.1
1.8
14.78
16.72
iu/l
0.33
99
799
7
44
1.58
0.64
2.0
2.0
—
—
—
0
0
416
3911
1.08
0.64
7.4
5.8
37.44
37.58
g/l
0.22
390
3693
95
827
1.15
0.63
10.0
5.8
63.55
61.53
ng/l
0.16
89
786
6
103
0.58
0.62
3.0
2.8
44.26
55.35
umol/l
—
6
93
27
344
0.78
0.62
1.2
1.2
—
—
—
0
0
211
1931
1.10
0.62
1.6
1.6
—
—
—
0
0
398
4171
0.93
0.61
5.6
3.8
25.97
67.37
e6/l
3.95
294
2781
810
7802
1.06
0.60
5.0
3.7
—
—
—
0
0
114
1010
1.13
0.60
7.5
8.6
106.04
105.07
mmol/l
1.36
114
1010
0
22
0.00
0.59
0.0
1.9
—
—
—
0
0
24
182
1.31
0.59
2.2
1.7
165.58
169.86
pmol/l
0.07
24
175
777
7480
1.06
0.58
4.7
3.6
89.71
520.57
e6/l
1.22
14
94
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
11
72
1.52
0.57
1.1
1.1
242.60
225.28
iu/ml
0.08
11
72
65
748
0.86
0.57
11.0
10.7
0.65
0.47
mmol/l
0.19
51
583
8
54
1.47
0.57
1.4
1.4
1.64
1.49
g/l
—
8
54
6
36
1.66
0.56
1.0
1.3
—
—
—
0
0
29
360
0.80
0.55
1.1
1.1
—
—
—
0
0
12
81
1.48
0.55
1.3
1.1
—
—
—
0
0
176
1607
1.10
0.55
11.0
7.2
1.50
1.51
mmol/l
0.02
148
1300
989
9601
1.06
0.55
3.3
3.1
5.50
5.55
mmol/l
0.66
905
8882
28
220
1.27
0.55
1.2
1.1
—
—
—
0
0
52
438
1.19
0.54
1.7
1.7
—
—
—
0
0
258
2399
1.08
0.54
1.6
1.7
—
—
—
0
0
63
540
1.17
0.54
1.1
1.1
16.60
6.88
u/ml
0.27
12
68
137
1238
1.11
0.53
1.8
1.9
—
—
—
0
0
638
6121
1.06
0.53
11.1
9.0
0.00
0.00
e9/l
0.23
556
4858
125
1125
1.11
0.52
4.6
3.3
9.33
10.07
g/l
1.54
118
1052
29
357
0.80
0.52
1.5
1.2
—
—
—
0
0
90
794
1.13
0.52
1.7
2.2
4.84
6.08
e9/l
0.40
76
701
250
2329
1.08
0.50
3.4
3.0
129.63
103.25
ug/g
0.36
207
1814
9
65
1.38
0.50
1.1
1.1
448.89
418.12
nmol/l
—
9
60
331
3119
1.07
0.49
3.1
2.9
2.37
2.37
mmol/l
0.19
298
2856
300
2821
1.07
0.47
1.7
1.7
—
—
—
0
0
1273
12478
1.07
0.47
9.6
8.3
23.99
25.38
u/l
1.42
1229
12084
155
1420
1.09
0.47
2.0
1.6
—
—
—
0
0
450
4657
0.94
0.47
1.6
1.6
1.33
2.31
u/ml
2.15
136
1044
200
1855
1.08
0.46
3.6
3.9
7.75
9.47
mg/mmol
0.21
128
1286
109
983
1.11
0.46
4.5
3.9
1.76
1.74
ug/l
0.05
98
891
8
118
0.67
0.45
1.0
1.0
—
—
—
0
0
5
82
0.60
0.45
1.2
1.5
—
—
—
0
0
5
82
0.60
0.45
1.0
1.4
—
—
—
0
0
29
237
1.22
0.43
2.4
3.1
21.19
26.90
mg/l
0.35
14
151
19
239
0.79
0.43
1.0
1.3
1.01
12.58
u/ml
—
8
129
17
130
1.30
0.42
1.6
1.7
—
—
—
0
0
77
685
1.12
0.42
1.8
1.5
—
—
—
0
0
11
78
1.40
0.42
1.3
1.8
42.83
50.19
%
—
6
57
305
3180
0.94
0.42
4.9
3.3
0.46
0.26
e6/l
0.39
244
2366
35
410
0.84
0.41
12.9
14.0
—
—
—
0
0
122
1316
0.91
0.41
2.1
2.3
2.41
2.42
mmol/l
0.51
113
1141
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
5
33
1.51
0.41
1.8
1.5
—
—
—
0
0
12
87
1.37
0.41
1.2
1.2
—
—
—
0
0
64
564
1.13
0.41
2.5
2.6
0.74
0.68
ug/l
0.28
31
327
348
3307
1.06
0.41
1.7
1.6
95.48
97.53
pmol/l
0.36
177
1749
8
59
1.35
0.40
5.4
3.1
0.18
0.17
e9/l
—
8
59
33
277
1.19
0.39
13.4
4.9
—
—
—
0
0
14
106
1.31
0.37
1.1
1.2
—
—
—
0
0
363
3464
1.05
0.37
9.6
7.7
—
—
—
0
0
155
1440
1.08
0.36
15.4
9.7
—
—
—
0
0
123
1132
1.09
0.36
13.8
5.9
24.55
24.27
mmol/l
0.74
123
1119
13
98
1.32
0.36
1.5
1.5
—
—
—
0
0
6
41
1.46
0.36
1.0
1.2
—
—
—
0
0
6
41
1.46
0.36
1.5
2.6
—
—
—
0
0
6
41
1.46
0.36
1.5
2.6
9.17
9.95
%
—
6
41
10
72
1.38
0.35
1.0
1.2
187.24
190.07
pmol/l
—
10
72
137
1270
1.08
0.35
6.6
4.3
6.93
6.88
umol/l
0.01
119
1078
28
327
0.85
0.34
1.6
1.9
2.81
5.43
iu/l
—
8
123
6
45
1.33
0.33
1.3
1.5
144.67
151.54
mmol/24h
—
6
45
114
1052
1.08
0.33
1.9
1.8
—
—
—
0
0
6
46
1.30
0.33
1.0
1.2
—
—
—
0
0
309
3194
0.95
0.32
4.8
3.3
—
—
—
0
0
11
142
0.77
0.32
1.4
1.7
—
—
—
0
0
104
1113
0.92
0.32
1.5
1.4
—
—
—
0
0
404
3883
1.04
0.31
1.6
1.6
—
—
—
0
0
1465
14468
1.07
0.31
17.1
14.8
40.00
40.12
%
0.45
1391
13690
122
1132
1.08
0.31
15.4
6.0
—
—
—
0
0
126
1171
1.07
0.31
1.7
1.8
—
—
—
0
0
80
729
1.09
0.31
1.5
1.4
—
—
—
0
0
11
83
1.32
0.31
1.7
1.6
—
—
—
0
0
12
92
1.30
0.30
1.2
1.6
4.02
5.96
ug/l
2.33
12
80
15
119
1.25
0.30
1.7
1.4
—
—
—
0
0
14
110
1.27
0.30
1.0
1.0
14.37
20.87
u/ml
—
6
65
146
1366
1.07
0.30
2.9
2.1
8031.07
6972.08
u/l
0.12
43
419
7
54
1.29
0.30
1.6
1.6
13.71
13.56
pmol/l
—
7
47
7
54
1.29
0.30
3.0
3.9
250.29
142.81
ug/l
—
7
54
75
683
1.10
0.30
1.7
1.6
—
—
—
0
0
1466
14482
1.07
0.29
16.8
14.5
88.50
88.33
fl
0.69
1443
14252
237
2254
1.05
0.29
4.3
2.8
579.33
587.47
mosm/kgh2o
0.16
211
1947
21
247
0.84
0.28
1.0
1.3
0.55
4.24
u/ml
—
7
150
56
504
1.11
0.28
1.4
1.2
—
—
—
0
0
1466
14486
1.07
0.28
16.8
14.5
29.66
29.56
pg
1.33
1443
14258
1466
14488
1.07
0.27
16.9
14.5
4.56
4.58
e12/l
1.25
1420
13947
1199
12022
0.96
0.26
14.3
12.7
334.27
333.76
g/l
1.09
1183
11887
77
709
1.08
0.25
1.1
1.1
9.24
7.95
u/ml
0.22
47
473
19
159
1.19
0.25
1.6
1.4
—
—
—
0
0
34
379
0.89
0.24
1.1
1.2
—
—
—
0
0
18
211
0.85
0.24
6.1
3.8
—
—
—
0
0
9
76
1.18
0.24
1.1
3.1
1820.00
863.20
u/ml
—
9
76
9
76
1.18
0.24
1.2
1.2
—
—
—
0
0
184
1909
0.95
0.24
3.6
2.9
0.54
1.03
e6/l
5.12
126
1019
9
77
1.16
0.24
1.3
1.2
—
—
—
0
0
25
216
1.15
0.24
1.1
1.1
—
—
—
0
0
1466
14495
1.06
0.24
16.9
14.5
6.60
6.63
e9/l
0.21
1422
13955
13
105
1.23
0.23
1.3
1.2
—
—
nmol/l
—
0
0
5
39
1.27
0.22
1.4
1.5
—
—
—
0
0
58
624
0.92
0.22
1.3
1.3
299.43
229.49
miu/ml
0.58
30
297
103
967
1.06
0.21
1.5
1.6
324.52
358.12
mu/l
0.42
88
888
1466
14500
1.06
0.21
17.1
14.6
134.76
134.94
g/l
0.21
1445
14274
39
351
1.11
0.21
3.4
2.8
5.59
12.59
e6/l
0.72
32
270
37
332
1.11
0.21
4.4
3.2
—
—
—
0
0
306
2953
1.04
0.21
1.5
1.6
—
—
—
0
0
24
209
1.14
0.21
7.0
3.8
1.48
1.32
mmol/l
0.31
24
203
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
187
1788
1.04
0.20
3.0
3.5
506.70
202.89
mg/l
0.31
116
1275
39
352
1.10
0.20
3.4
2.8
92.48
149.90
e6/l
0.34
33
281
0
14
0.00
0.20
0.0
1.6
—
—
—
0
0
0
14
0.00
0.20
0.0
8.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
10
122
0.81
0.20
4.5
15.9
12.75
11.51
%
—
10
122
31
342
0.90
0.20
3.8
6.2
—
—
—
0
0
20
227
0.87
0.19
1.1
1.3
4.11
4.95
u/ml
—
9
104
1463
14475
1.05
0.19
17.0
14.6
264.54
265.32
e9/l
0.19
1418
13977
26
230
1.13
0.19
4.0
10.4
—
—
—
0
0
25
221
1.13
0.18
1.2
1.1
—
—
—
0
0
17
146
1.16
0.18
1.5
1.1
—
—
—
0
0
13
152
0.85
0.18
1.9
2.2
—
—
—
0
0
45
413
1.08
0.18
1.7
1.6
—
—
—
0
0
340
3456
0.97
0.17
5.1
3.4
18.90
46.79
e6/l
3.99
282
2597
54
500
1.08
0.17
1.1
1.1
8.15
5.13
u/ml
0.58
36
297
198
1904
1.04
0.17
1.5
1.4
20.90
19.71
nmol/l
0.56
168
1681
20
175
1.14
0.17
1.1
1.1
—
—
—
0
0
5
66
0.75
0.17
1.0
1.1
—
—
—
0
0
73
685
1.06
0.17
1.1
1.1
2.44
1.39
u/ml
0.28
37
412
276
2812
0.97
0.17
6.2
5.0
90.40
91.17
%
0.24
267
2743
36
328
1.09
0.16
3.7
2.9
—
—
—
0
0
76
796
0.95
0.16
1.3
1.3
—
—
—
0
0
8
72
1.10
0.16
2.4
2.1
9.41
2.31
nmol/l
—
8
58
12
101
1.18
0.15
3.5
5.0
410.50
203.76
umol/l
—
6
66
16
181
0.88
0.15
1.3
1.6
—
—
—
0
0
16
139
1.14
0.15
1.9
1.5
—
—
—
0
0
11
92
1.19
0.15
2.1
2.0
—
—
—
0
0
131
1255
1.04
0.14
1.3
1.3
147.20
151.62
iu/ml
0.04
52
445
8
95
0.84
0.13
1.3
1.0
—
—
—
0
0
8
99
0.80
0.13
1.3
1.1
—
—
—
0
0
11
127
0.86
0.13
4.5
2.1
—
—
—
0
0
22
198
1.11
0.13
1.2
1.1
—
—
—
0
0
480
4704
1.02
0.12
13.2
7.7
1.23
1.22
mmol/l
0.50
447
4418
14
157
0.88
0.12
2.6
2.0
13.19
13.12
%
0.12
14
157
15
132
1.13
0.12
1.0
1.2
—
—
—
0
0
14
123
1.13
0.11
1.5
1.2
—
—
—
0
0
30
277
1.08
0.11
1.2
1.5
—
—
—
0
0
14
156
0.89
0.11
1.7
1.8
—
—
—
0
0
48
452
1.06
0.11
1.0
1.1
9.28
8.21
u/ml
0.15
24
243
29
268
1.08
0.10
1.1
1.1
18.44
202.99
iu/ml
—
8
85
20
182
1.09
0.10
1.6
1.4
—
—
—
0
0
106
1022
1.03
0.10
1.9
2.2
—
—
—
0
0
5
46
1.08
0.09
1.0
1.1
—
—
—
0
0
73
699
1.04
0.09
1.7
2.2
—
—
—
0
0
5
47
1.06
0.09
3.8
8.4
—
—
—
0
0
5
47
1.06
0.09
1.4
1.4
—
—
—
0
0
74
761
0.96
0.09
1.2
1.2
—
—
—
0
0
146
1483
0.98
0.08
3.4
3.1
516.78
840.66
ng/l
0.77
82
810
81
779
1.03
0.08
1.2
1.2
6.92
3.79
u/ml
0.56
46
487
10
87
1.14
0.08
1.6
1.1
—
—
—
0
0
10
87
1.14
0.08
6.3
6.7
—
—
—
0
0
28
261
1.07
0.08
2.1
2.2
—
—
—
0
0
36
377
0.95
0.08
1.2
1.6
0.19
0.30
nmol/l
3.05
31
310
36
339
1.06
0.08
1.1
1.1
5.39
4.41
u/ml
0.09
16
116
16
145
1.10
0.08
2.7
2.3
18.50
153.72
ug/min
—
8
93
7
63
1.10
0.08
1.1
1.2
—
3.00
u/ml
—
0
8
7
64
1.09
0.08
1.0
1.1
—
46.33
—
0
6
652
6430
1.01
0.08
3.0
2.6
—
—
—
0
0
7
82
0.85
0.07
1.7
1.1
—
—
—
0
0
47
449
1.04
0.07
1.5
1.6
—
8.26
—
0
18
122
1187
1.02
0.07
4.8
3.9
0.23
0.22
g/l
0.29
117
1133
8
93
0.85
0.06
3.1
3.7
—
—
—
0
0
22
232
0.94
0.06
2.1
2.0
7.18
1.41
ug/l
0.56
17
209
19
177
1.07
0.05
1.1
1.2
9.70
9.43
u/ml
—
10
132
79
803
0.98
0.05
1.5
1.3
—
—
—
0
0
71
688
1.03
0.05
1.1
1.1
2.96
3.44
u/ml
0.15
48
457
33
315
1.04
0.05
1.8
1.9
—
—
—
0
0
14
149
0.93
0.04
1.4
1.4
90.00
269.38
titre
—
6
32
33
316
1.04
0.04
1.3
1.4
—
12.95
—
0
6
125
1225
1.01
0.04
1.2
1.3
—
—
—
0
0
14
148
0.94
0.03
1.1
1.1
1.38
1.45
g/l
0.48
14
138
39
398
0.97
0.03
1.6
1.4
—
—
—
0
0
412
4112
0.99
0.03
1.5
1.5
1.89
1.85
g/l
0.20
269
2304
246
2427
1.01
0.03
1.7
1.7
1.37
1.32
mmol/l
0.16
207
2162
27
260
1.03
0.02
1.6
1.7
0.74
0.83
g/l
0.17
21
205
40
405
0.98
0.01
1.6
1.5
—
—
—
0
0
39
395
0.98
0.01
1.6
1.4
—
—
—
0
0
18
172
1.04
0.01
2.9
2.8
—
—
—
0
0
35
354
0.98
0.00
1.4
1.4
4.54
5.51
ug/l
0.35
30
326
370
3668
1.00
0.00
4.3
3.5
29.75
30.13
u/l
0.09
361
3515
22
219
1.00
0.00
3.4
5.0
407.18
396.63
umol/l
0.12
22
200
16
154
1.03
0.00
1.1
1.2
35.90
16.06
u/ml
—
10
120
39
389
1.00
0.00
1.1
1.1
0.04
0.65
u/ml
2.26
13
136
10
96
1.04
0.00
1.4
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
9
98
0.91
0.00
2.7
2.6
36022.22
40167.40
ug/l
—
9
98
0
6
0.00
0.00
0.0
1.0
—
32.41
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
4.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
62
0.96
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
2.42
—
0
5
7
72
0.97
-0.00
1.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1605.00
—
0
5
5
57
0.87
-0.00
1.0
1.4
63.80
66.95
umol/l
—
5
57
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
69
1.01
-0.00
1.6
1.3
1.26
1.24
nmol/l
—
7
62
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
-0.00
3.0
4.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
150.20
—
0
5
0
8
0.00
-0.00
0.0
1.9
—
9368.75
—
0
8
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
250.00
—
0
5
7
74
0.94
-0.00
1.1
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_DISTAL_BITE and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
K11_DISTAL_BITE 0.943 [0.66, 1.34] 0.747
Birth year 0.987 [0.98, 1.0] 0.025

During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 28247 males with K11_DISTAL_BITE died.

Mortality risk

Mortality risk for people of age

years, who have K11_DISTAL_BITE.

N-year risk Females Males
1 No data 0.125%
5 No data 0.954%
10 No data 2.553%
15 No data 5.051%
20 No data 8.891%

Relationships between endpoints

Index endpoint: K11_DISTAL_BITE – Distal bite

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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