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Progressive vascular leukoencephalopathy

DOID EFO Endpoint Browser PheWeb

I9_PROGVASC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — I67.3
  • Cause of death: ICD-10 — I67.3

2 out of 7 registries used, show all original rules.

1407

4. Check minimum number of events

None

1407

5. Include endpoints

None

1407

6. Filter based on genotype QC (FinnGen only)

1359

Control definitions (FinnGen only)

Control exclude
I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I67
Name in latin
Leucoencephalopathia vascularis progressiva

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8396 4988 3358
Only index persons 7636 4604 3032
Unadjusted period prevalence (%)
Whole population 0.12 0.14 0.09
Only index persons 0.15 0.17 0.12
Median age at first event (years)
Whole population 80.45 81.63 78.75
Only index persons 80.80 81.89 79.13

-FinnGen-

Key figures

All Female Male
Number of individuals 1359 721 638
Unadjusted period prevalence (%) 0.27 0.26 0.29
Median age at first event (years) 80.50 81.00 79.93

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1407
Matched controls
14070
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
4503599627370496.0
307.7
1405
44
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
104.9
307.7
324
40
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
162.5
307.7
335
27
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
12.7
307.7
736
1122
R41.3
ICD-10 Finland
Other amnesia
13.3
291.7
305
287
R4110
NOMESCO Finland
Physiotherapy
6.1
255.7
829
2661
Z2221
NOMESCO Finland
Medical doctor
5.2
210.5
757
2558
G30.1
ICD-10 Finland
Alzheimer disease with late onset
5.5
185.7
471
1174
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
4.8
185.3
691
2355
Z71.8
ICD-10 Finland
Other specified counselling
4.2
151.0
657
2437
Z01.9
ICD-10 Finland
Special examination, unspecified
7.1
148.9
249
412
R4120
NOMESCO Finland
Occupational therapy
8.2
140.1
202
283
Z3226
NOMESCO Finland
Physiotherapist
4.2
136.6
511
1682
AA1AD
NOMESCO Finland
CT of head and brain
3.8
131.7
700
2918
R5110, ,
SPAT
5.4
129.5
299
670
XA800
NOMESCO Finland
Neuropsychological investigation
16.6
126.0
108
70
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
7.1
124.3
205
332
ZXD10
NOMESCO Finland
Scheduled procedure
3.6
121.2
847
4146
Z76.0
ICD-10 Finland
Issue of repeat prescription
3.9
116.0
469
1606
N06DX01
ATC
memantine; oral
3.9
115.3
446
1481
Z3231
NOMESCO Finland
Registered nurse
3.5
112.9
651
2796
P20
ICPC
Memory disturbance
3.5
107.5
576
2350
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
292.9
107.5
108
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
7.0
105.6
173
277
XF400
NOMESCO Finland
ECG with 12 standard connections
3.6
105.4
472
1716
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
5.1
104.9
252
579
Z01.7
ICD-10 Finland
Laboratory examination
3.9
98.4
362
1148
R53
ICD-10 Finland
Malaise and fatigue
3.2
97.2
592
2579
A28
ICPC
Limited function/disability NOS
3.2
97.1
629
2840
F01.9
ICD-10 Finland
Vascular dementia, unspecified
10.0
94.5
111
119
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
7.6
81.0
119
168
ZXE00
NOMESCO Finland
One hour or less
2.8
76.5
734
3968
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.2
75.4
400
1572
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
74.0
524
2413
WX002
NOMESCO Finland
Sedation and analgesia
2.9
73.6
475
2081
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.5
71.7
300
1018
ZXA05
NOMESCO Finland
Left side
2.6
66.7
596
3056
R4130
NOMESCO Finland
Speech therapy
10.2
66.5
76
78
ZXA00
NOMESCO Finland
Right side
2.6
66.1
619
3245
R42
ICD-10 Finland
Dizziness and giddiness
2.7
65.1
546
2707
WX110, ,
SPAT
5.5
64.6
131
256
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
62.5
680
3800
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.3
62.3
280
987
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.5
60.1
700
4016
U13
ICPC
Bladder symptom/complaint other
5.4
59.3
123
245
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
3.6
59.1
218
677
Z71.9
ICD-10 Finland
Counselling, unspecified
4.1
58.7
178
482
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
56.6
54
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.2
56.2
160
413
EB1AA, ,
SPAT
4.6
55.7
140
328
Z73.6
ICD-10 Finland
Limitation of activities due to disability
10.6
54.9
61
60
Z71
ICD-10 Finland
Persons encountering health services for other counselling and medical advice, not elsewhere classified
6.9
54.4
86
131
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.2
53.8
253
911
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.5
53.8
208
664
B01AC04
ATC
clopidogrel; oral
2.6
53.8
394
1801
C10AA05
ATC
atorvastatin; oral
2.3
52.8
782
4895
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
52.4
301
1212
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.3
51.5
143
362
ZXD35
NOMESCO Finland
Usual procedure
5.2
50.2
107
218
K90
ICPC
Stroke/cerebrovascular accident
11.0
49.1
53
50
XCK10
NOMESCO Finland
Photography of fundus of eye
2.9
48.9
268
1049
N06DA03
ATC
rivastigmine; oral, transdermal
3.3
47.0
204
697
N05AX08
ATC
risperidone; systemic
3.0
46.5
241
913
F03
ICD-10 Finland
Unspecified dementia
3.3
45.3
186
614
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
86.4
45.1
50
6
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.8
44.9
258
1033
N06AX11
ATC
mirtazapine; oral
2.2
43.9
577
3363
WX892
NOMESCO Finland
Monitored bed care
3.3
43.1
180
600
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
+∞
42.9
41
*
Z02.7
ICD-10 Finland
Issue of medical certificate
3.3
42.2
173
570
ZXD20
NOMESCO Finland
Day surgery
2.7
42.1
266
1116
TAB00
NOMESCO Finland
Lumbar puncture
5.3
41.6
87
174
N06DA04
ATC
galantamine; oral
4.0
41.2
126
341
M79.6
ICD-10 Finland
Pain in limb
2.1
41.2
653
4067
TKC20
NOMESCO Finland
Catheterisation of bladder
3.1
41.0
194
695
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.3
41.0
415
2161
Z2446
NOMESCO Finland
Social worker
3.7
40.9
141
415
U72
ICPC
Urethritis
5.6
39.8
78
147
N06AX26
ATC
vortioxetine; oral
4.1
39.8
113
290
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
4.2
39.3
110
279
PA6AD
NOMESCO Finland
CT of neck arteries
6.5
39.2
65
104
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.4
39.1
101
241
WYA30, ,
SPAT
13.1
38.4
37
29
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.8
38.3
122
340
Z2445
NOMESCO Finland
Psychologist
8.7
37.5
48
57
F01.2
ICD-10 Finland
Subcortical vascular dementia
10.5
37.0
41
40
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
366.4
36.1
36
*
M54
ICD-10 Finland
Dorsalgia
2.8
36.1
208
828
I10
ICD-10 Finland
Essential (primary) hypertension
2.3
36.1
1109
8680
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
82.4
36.0
40
5
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
355.8
35.1
35
*
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
2.2
34.4
367
1934
H81
ICPC
Excessive ear wax
2.2
34.2
396
2154
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.5
33.6
123
376
N17
ICPC
Vertigo/dizziness
2.4
33.5
291
1405
A98
ICPC
Health maint/preventive medicine
3.2
32.3
1299
11106
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
6.0
31.5
56
96
F06.7
ICD-10 Finland
Mild cognitive disorder
3.5
31.4
116
356
N30.0
ICD-10 Finland
Acute cystitis
2.2
31.1
321
1661
Z46.9
ICD-10 Finland
Fitting and adjustment of unspecified device
5.8
31.0
57
101
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
4.0
30.6
89
232
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
4.1
30.4
87
224
R1260
NOMESCO Finland
Evaluation of communicative skills
6.2
30.3
52
86
SPAT1256
SPAT
Intramuscular and subcutaneous injection
0.5
30.3
267
4816
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
158.4
29.8
31
*
IGY02
NOMESCO Finland
Psychiatric monitoring contact
9.0
29.0
36
41
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.9
29.0
87
232
S01.0
ICD-10 Finland
Open wound of scalp
2.6
28.4
176
723
GD1LA
NOMESCO Finland
GD
5.5
28.4
56
106
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
9.4
28.3
34
37
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
9.4
28.3
34
37
XF404
NOMESCO Finland
Ambulatory ECG
2.5
28.1
195
846
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
7.2
28.1
42
60
F05.9
ICD-10 Finland
Delirium, unspecified
4.2
28.0
76
188
R51.80
ICD-10 Finland
Headache
2.5
27.9
195
849
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
10.2
27.4
31
31
SPAT1263
SPAT
Sampling
0.5
27.4
263
4650
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
27.3
401
2353
ZXA10
NOMESCO Finland
Bilateral
2.0
27.2
392
2285
SPAT1153
SPAT
Removal of sutures
0.4
27.2
180
3667
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.2
27.1
115
384
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.6
27.1
93
272
R41.0
ICD-10 Finland
Disorientation, unspecified
3.5
27.0
98
297
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
27.0
288
1501
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.1
26.5
308
1658
EBA00, ,
SPAT
4.6
26.4
63
141
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
26.3
189
833
C07AB07
ATC
bisoprolol; oral
1.9
26.1
913
7014
A23
ICPC
Risk factor NOS
3.1
26.0
115
394
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
3.8
25.8
81
223
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.9
25.7
416
2514
C08CA01
ATC
amlodipine; oral
1.8
25.7
733
5285
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.2
25.6
105
344
M25.5
ICD-10 Finland
Pain in joint
1.9
24.9
400
2409
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.1
24.6
259
1340
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.3
24.5
213
1020
R05
ICD-10 Finland
Cough
2.0
24.4
329
1865
N05AH04
ATC
quetiapine; oral
2.2
24.3
236
1181
N06DA02
ATC
donepezil; oral
2.2
24.3
221
1077
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
24.3
286
1542
N30
ICD-10 Finland
Cystitis
2.6
24.2
153
633
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.0
24.2
69
177
N03AG01
ATC
valproic acid; systemic, rectal
3.4
24.1
88
268
N02BE01
ATC
paracetamol; systemic, rectal
2.5
23.9
1265
11014
SPAT1053
SPAT
Memory test
1.9
23.8
406
2486
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
23.8
142
571
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.1
23.6
100
334
M54.5
ICD-10 Finland
Low back pain
1.8
23.4
485
3155
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
47.5
23.4
28
6
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.8
23.0
118
439
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
+∞
23.0
22
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
22.9
364
2174
F01.20
ICD-10 Finland
Subcortical vascular dementia without additional symptoms
5.5
22.7
44
82
I95.1
ICD-10 Finland
Orthostatic hypotension
2.8
22.7
123
471
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
122.0
22.6
24
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
22.6
484
3171
XF402
NOMESCO Finland
ECG with work load test
2.2
22.6
215
1066
A97
ICPC
No disease
2.0
22.5
303
1710
K91
ICPC
Cerebrovascular disease
8.9
22.5
28
32
R52.9
ICD-10 Finland
Pain, unspecified
2.4
22.2
162
717
EB1SA, ,
SPAT
3.8
22.1
69
189
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
21.9
765
5743
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
6.8
21.7
34
51
SPAT1312
SPAT
General health counselling
0.4
21.5
156
3125
R60.0
ICD-10 Finland
Localized oedema
2.0
21.5
263
1433
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
21.4
322
1884
S06.0
ICD-10 Finland
Concussion
2.3
21.3
181
855
I25
ICD-10 Finland
Chronic ischaemic heart disease
2.5
21.3
138
578
A98
ICD-10 Finland
Other viral haemorrhagic fevers, not elsewhere classified
5.4
21.2
42
80
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
21.1
402
2533
H53.1
ICD-10 Finland
Subjective visual disturbances
2.9
20.9
105
386
L28
ICPC
Limited function/disability (L)
1.8
20.6
397
2509
315
Kela drug reimbursment
Clopidogrel
6.6
20.5
33
51
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.4
20.3
76
235
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
8.5
20.2
26
31
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
3.7
20.1
66
187
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
20.1
188
923
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
20.1
847
6623
M03BC01
ATC
orphenadrine (citrate); systemic
2.0
19.9
243
1320
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
19.8
19
*
G04BD12
ATC
mirabegron; oral
2.0
19.6
252
1394
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
19.5
190
948
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
19.5
439
2895
L84
ICD-10 Finland
Corns and callosities
3.2
19.5
80
262
WX320
NOMESCO Finland
Spinalanesthesy
1.8
19.4
413
2678
J01DB01
ATC
cefalexin; oral
1.8
19.4
1090
9189
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
19.2
282
1630
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
19.2
476
3222
R20.2
ICD-10 Finland
Paraesthesia of skin
2.9
19.2
91
324
N06AB10
ATC
escitalopram; oral
2.0
19.2
219
1161
WX290, ,
SPAT
4.4
19.1
48
112
SPAT1301
SPAT
No procedures
0.5
19.0
225
3829
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
18.9
357
2234
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
18.8
201
1039
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
18.8
454
3048
A02BC02
ATC
pantoprazole; systemic
1.7
18.7
975
7993
Z50.1
ICD-10 Finland
Other physical therapy
2.6
18.7
116
475
F32
ICD-10 Finland
Depressive episode
3.6
18.5
63
183
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.7
18.5
59
164
G46.8*I67.9
ICD-10 Finland
Other vascular syndromes of brain in cerebrovascular diseases
30.5
18.4
24
8
G45
ICD-10 Finland
Transient cerebral ischaemic attacks and related syndromes
6.7
18.3
29
44
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
5.4
18.3
36
68
I63
ICD-10 Finland
Cerebral infarction
44.6
18.3
22
5
TNX99
NOMESCO Finland
Other orthopaedic minor procedure
3.7
18.2
58
161
XF606
NOMESCO Finland
Ortostatic test
6.4
18.1
30
48
EBA30
NOMESCO Finland
Extraction of root of tooth
2.6
18.0
111
453
G44.2
ICD-10 Finland
Tension-type headache
2.2
18.0
166
810
I67.8
ICD-10 Finland
Other specified cerebrovascular diseases
53.2
18.0
21
*
EBA05, ,
SPAT
5.2
17.9
37
73
ZXC20
NOMESCO Finland
Use of chemical agents
3.4
17.9
66
202
I50
ICD-10 Finland
Heart failure
2.6
17.7
107
433
J20
ICD-10 Finland
Acute bronchitis
2.2
17.5
154
736
I63.8
ICD-10 Finland
Other cerebral infarction
182.2
17.5
18
*
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
2.6
17.5
102
405
N03AX14
ATC
levetiracetam; systemic
4.4
17.4
44
103
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
0.5
17.4
179
3207
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
24.4
17.3
24
10
D11
ICPC
Diarrhoea
2.2
17.1
153
737
F05.1
ICD-10 Finland
Delirium superimposed on dementia
5.3
17.1
34
65
N06AX21
ATC
duloxetine; oral
2.2
17.0
157
765
N03AX16
ATC
[U] pregabalin
1.7
16.9
352
2257
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
16.8
241
1378
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.9
16.8
79
280
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
16.8
286
1728
Z01.3
ICD-10 Finland
Examination of blood pressure
4.4
16.7
42
98
I67.4
ICD-10 Finland
Hypertensive encephalopathy
+∞
16.7
16
*
ZXD05
NOMESCO Finland
Urgent procedure
1.7
16.5
441
3022
C10AA01
ATC
simvastatin; oral
1.6
16.5
786
6204
N06AB04
ATC
citalopram; systemic
1.8
16.5
284
1721
B01AF02
ATC
apixaban; oral
1.8
16.3
290
1773
SPAT1336
SPAT
Request for examination
2.8
16.3
85
319
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
16.2
265
1578
S16
ICPC
Bruise/contusion
2.9
16.2
78
280
R06.0
ICD-10 Finland
Dyspnoea
1.6
16.2
464
3233
J45
ICD-10 Finland
Asthma
2.2
16.2
153
753
F51.0
ICD-10 Finland
Nonorganic insomnia
2.1
15.9
168
862
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.0
15.9
176
919
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.4
15.8
114
500
D12
ICPC
Constipation
2.6
15.8
93
371
Z20.8
ICD-10 Finland
Contact with and exposure to other communicable diseases
3.5
15.7
55
163
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
+∞
15.7
15
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.8
15.6
250
1478
SPAT1310
SPAT
Counselling related to known health issue
0.5
15.6
194
3292
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.5
15.6
100
416
WX212
NOMESCO Finland
Femoral plexus blockade
3.1
15.5
67
226
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
15.5
340
2204
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.0
15.4
195
1067
EBA30, ,
SPAT
12.5
15.4
27
22
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.5
15.3
98
407
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
15.3
234
1364
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
11.9
15.1
27
23
SPAT1342
SPAT
Referral to specialised care
4.6
15.0
35
77
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.0
15.0
173
917
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
5.6
14.8
28
51
N01
ICPC
Headache
2.3
14.6
114
518
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
+∞
14.6
14
*
Z01.2
ICD-10 Finland
Dental examination
1.6
14.6
462
3283
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.6
14.5
418
2900
TNG34
NOMESCO Finland
Major custom moulded orthopaedic cast, knee or lower leg
4.9
14.5
32
67
U07
ICPC
Urine symptom/complaint other
2.1
14.4
144
724
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.1
14.1
134
660
W06
ICD-10 Finland
Fall involving bed
5.0
14.1
30
61
R55
ICD-10 Finland
Syncope and collapse
1.8
14.1
217
1266
W19
ICD-10 Finland
Unspecified fall
2.0
14.1
172
930
R51
ICD-10 Finland
Headache
2.9
14.0
65
229
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
14.0
344
2291
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
14.0
144
732
N05BA01
ATC
diazepam; systemic, rectal
1.9
14.0
202
1155
XF600
NOMESCO Finland
Bloodpressure measurement
2.2
13.9
120
569
SPAT1097
SPAT
Recording of ECG
0.4
13.8
77
1753
R83
ICPC
Respiratory infection other
1.9
13.8
181
1001
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
53.9
13.8
16
*
G30.8
ICD-10 Finland
Other Alzheimer disease
2.6
13.8
83
335
M79.1
ICD-10 Finland
Myalgia
1.9
13.7
175
960
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.0
13.7
152
794
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
13.6
262
1631
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
2.3
13.6
103
462
R49.03
ICD-10 Finland
Atrophic dysphonia
4.1
13.6
37
92
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
13.6
13
*
D07AB08
ATC
desonide; topical
2.0
13.5
164
884
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
3.4
13.5
49
149
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
13.5
221
1313
N03AF02
ATC
oxcarbazepine; oral
3.7
13.5
43
120
-44
ICPC
Preventive immunization/medic
0.2
13.5
24
980
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
6.1
13.4
23
38
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
13.4
184
1034
H02BX01
ATC
methylprednisolone, combinations; systemic
2.2
13.3
122
593
R26.2
ICD-10 Finland
Difficulty in walking, not elsewhere classified
4.0
13.2
37
94
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
0.6
13.2
213
3382
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.9
13.1
61
215
M19
ICD-10 Finland
Other arthrosis
3.2
13.1
52
167
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.8
13.1
67
249
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
11.1
13.0
24
22
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.1
12.9
129
647
207
Kela drug reimbursment
Chronic arrhythmias
1.6
12.9
358
2449
S09.9
ICD-10 Finland
Unspecified injury of head
3.8
12.9
39
105
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
3.5
12.8
43
124
A04
ICPC
Weakness/tiredness general
1.7
12.8
270
1721
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
0.6
12.8
230
3554
R39.1
ICD-10 Finland
Other difficulties with micturition
2.9
12.7
60
214
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
2.4
12.6
90
393
I67.2
ICD-10 Finland
Cerebral atherosclerosis
17.5
12.5
19
11
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
+∞
12.5
12
*
EB1HA, ,
SPAT
4.0
12.5
35
89
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.4
452
3290
R2110
NOMESCO Finland
Giving the first information
2.4
12.4
85
365
K08.3
ICD-10 Finland
Retained dental root
2.1
12.3
116
569
F01.30
ICD-10 Finland
Mixed cortical and subcortical vascular dementia without additional symptoms
9.7
12.2
24
25
R41
ICD-10 Finland
Other symptoms and signs involving cognitive functions and awareness
4.3
12.2
31
73
K59.0
ICD-10 Finland
Constipation
2.1
12.2
117
578
R73
ICD-10 Finland
Elevated blood glucose level
2.9
12.2
57
202
C09CA01
ATC
losartan; oral
1.6
12.1
423
3051
L17
ICPC
Foot/toe symptom/complaint
1.6
12.0
403
2880
E78
ICD-10 Finland
Disorders of lipoprotein metabolism and other lipidaemias
2.6
11.9
70
279
SPAT1249
SPAT
Treatment-related counselling outside office
0.6
11.9
283
4091
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
5.4
11.8
23
43
D64.9
ICD-10 Finland
Anaemia, unspecified
1.7
11.8
225
1393
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.2
11.8
97
451
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.4
11.7
81
349
G04CA02
ATC
tamsulosin; oral
1.5
11.7
408
2936
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
0.5
11.6
159
2661
RS222, ,
NOMESCO Finland
4.1
11.6
31
76
ZY010
NOMESCO Finland
Hospital outpatient
3.1
11.6
49
164
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
2.2
11.6
105
508
S20.2
ICD-10 Finland
Contusion of thorax
2.4
11.5
79
340
Z04
ICD-10 Finland
Examination and observation for other reasons
3.8
11.4
35
95
K05.19
ICD-10 Finland
Gingivitis (chronic) ulcerative
3.7
11.4
36
100
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
11.4
221
1376
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.7
11.3
206
1259
WX720
NOMESCO Finland
Own respiration
0.0
11.3
*
312
A02BC05
ATC
esomeprazole; systemic
1.5
11.3
531
4064
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.5
11.3
68
275
R25.1
ICD-10 Finland
Tremor, unspecified
2.7
11.2
59
223
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.9
11.2
152
850
H81.3
ICD-10 Finland
Other peripheral vertigo
2.8
11.2
54
195
H10.5
ICD-10 Finland
Blepharoconjunctivitis
4.2
11.1
29
70
WX402
NOMESCO Finland
General anaesthesia
1.7
11.1
220
1377
UJD10, ,
SPAT
3.5
11.0
38
112
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.7
10.9
58
220
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
1.8
10.9
186
1115
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
10.9
650
5204
R52.0
ICD-10 Finland
Acute pain
3.0
10.8
47
160
S22.3
ICD-10 Finland
Fracture of rib
2.0
10.8
114
585
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.2
10.8
89
415
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.9
10.7
134
728
S00.0
ICD-10 Finland
Superficial injury of scalp
2.8
10.7
52
188
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
3.3
10.7
40
124
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.5
10.7
69
288
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
2.7
10.7
58
223
H02AB07
ATC
prednisone; oral
1.7
10.6
219
1383
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.1
10.6
105
526
N05AH03
ATC
olanzapine; systemic
2.5
10.6
68
284
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
10.5
447
3341
Z76
ICD-10 Finland
Persons encountering health services in other circumstances
4.5
10.5
25
56
I48.2
ICD-10 Finland
Chronic atrial fibrillation
2.1
10.5
100
494
K02.1
ICD-10 Finland
Caries of dentine
1.5
10.4
564
4418
I61.8
ICD-10 Finland
Other intracerebral haemorrhage
110.8
10.4
11
*
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
+∞
10.4
10
*
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
+∞
10.4
10
*
R07.0
ICD-10 Finland
Pain in throat
2.5
10.4
66
274
KMAK, ,
NOMESCO Finland
1.5
10.4
517
3986
XKD00
NOMESCO Finland
Uroflowmetry
1.6
10.4
273
1835
IAB14
NOMESCO Finland
Geriatric psychiatry consultation
12.1
10.4
18
15
M03BC51
ATC
orphenadrine, combinations; systemic
1.6
10.3
299
2055
C09AA05
ATC
ramipril; oral
1.5
10.3
440
3288
S30.0
ICD-10 Finland
Contusion of lower back and pelvis
2.5
10.3
65
269
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.7
10.3
223
1427
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
18.9
10.3
15
8
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
18.9
10.3
15
8
L82
ICD-10 Finland
Seborrhoeic keratosis
1.6
10.2
265
1774
130
Kela drug reimbursment
Malignant tumour
0.3
10.2
36
1012
F45.8
ICD-10 Finland
Other somatoform disorders
3.0
10.1
45
155
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
10.1
189
1162
C03CA01
ATC
furosemide; systemic
1.4
10.1
677
5512
R06AE07
ATC
cetirizine; oral
1.5
10.1
483
3690
SPAT1304
SPAT
Counselling and guidance related to ageing
0.4
10.1
56
1284
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.7
10.0
176
1063
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
10.0
586
4649
G81.9
ICD-10 Finland
Hemiplegia, unspecified
10.1
10.0
19
19
N30.9
ICD-10 Finland
Cystitis, unspecified
2.0
10.0
114
601
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.8
10.0
161
949
R32
ICD-10 Finland
Unspecified urinary incontinence
2.5
10.0
61
249
R29.6
ICD-10 Finland
Tendency to fall, not elsewhere classified
7.7
9.9
22
29
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
9.9
259
1737
Z26.9
ICD-10 Finland
Need for immunization against unspecified infectious disease
3.9
9.9
28
72
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
2.9
9.9
46
163
R13
ICD-10 Finland
Dysphagia
2.0
9.8
109
569
K43
ICPC
Cardiovascular, Other diagnostic procedure
3.5
9.8
33
96
Z29.8
ICD-10 Finland
Other specified prophylactic measures
3.5
9.8
33
96
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.0
9.8
111
584
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
2.0
9.8
100
507
M54.8
ICD-10 Finland
Other dorsalgia
2.5
9.7
61
252
TQW99
NOMESCO Finland
Other minor procedure on skin
2.0
9.7
104
536
Z51.88
ICD-10 Finland
Other specified medical care
2.9
9.7
45
159
SPAT1260
SPAT
Consultation of another employee
0.5
9.7
98
1808
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
9.7
89
433
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.1
9.7
91
447
SPAT1043
SPAT
Audiometry
0.4
9.6
61
1329
XX9CW
NOMESCO Finland
Submitting image material and/or investigation material to patient
5.3
9.6
19
36
I84
ICD-10 Finland
Hemorrhoids
2.6
9.6
54
211
ZA1.0
ICD-10 Finland
Shoulder region
2.9
9.6
43
149
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
9.6
558
4413
X58
ICD-10 Finland
Exposure to other specified factors
1.8
9.6
149
869
J01CF05
ATC
flucloxacillin; systemic
2.1
9.5
85
409
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.8
9.5
47
172
U07.2
ICD-10 Finland
COVID-19, virus not identified
2.2
9.5
83
396
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.7
9.5
183
1135
F00
ICD-10 Finland
Dementia in Alzheimer disease
7.6
9.4
21
28
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
9.4
671
5499
M15
ICD-10 Finland
Polyarthrosis
2.0
9.4
110
585
UJF32
NOMESCO Finland
Coloscopy
1.5
9.4
396
2943
I61.4
ICD-10 Finland
Intracerebral haemorrhage in cerebellum
+∞
9.4
9
*
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
+∞
9.4
9
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
9.3
476
3670
R07.3
ICD-10 Finland
Other chest pain
1.8
9.3
152
899
A11
ICPC
Chest pain NOS
1.8
9.3
146
854
J01CA04
ATC
amoxicillin; systemic
1.5
9.3
987
8682
M81.5
ICD-10 Finland
Idiopathic osteoporosis
4.1
9.3
25
62
B01AB05
ATC
enoxaparin; parenteral
1.4
9.2
470
3621
XKD06
NOMESCO Finland
Physiologic investigation of micturition
2.6
9.2
54
216
N03AX09
ATC
lamotrigine; oral
3.4
9.2
33
100
G04BD08
ATC
solifenacin; oral
1.8
9.2
133
759
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
2.2
9.1
73
336
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
9.1
212
1380
R47.8
ICD-10 Finland
Other and unspecified speech disturbances
4.5
9.1
22
50
R35
ICD-10 Finland
Polyuria
1.9
9.1
117
643
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.9
9.0
26
68
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.6
9.0
29
82
I83
ICD-10 Finland
Varicose veins of lower extremities
2.9
9.0
41
144
IBZ07
NOMESCO Finland
Neurological assessment in psychiatry
18.7
8.9
13
7
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
8.9
181
1137
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
2.8
8.9
45
167
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
4.0
8.9
25
64
L60.8
ICD-10 Finland
Other nail disorders
4.5
8.8
21
47
1LA05, ,
NOMESCO Finland
4.7
8.8
20
43
R26
ICD-10 Finland
Abnormalities of gait and mobility
10.8
8.8
16
15
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.5
8.8
266
1841
R12
ICD-10 Finland
Heartburn
2.0
8.8
98
513
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.6
8.7
238
1609
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
8.7
143
847
K30
ICD-10 Finland
Functional dyspepsia
1.8
8.7
134
779
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
6.6
8.7
21
32
Z13.5
ICD-10 Finland
Special screening examination for eye and ear disorders
4.4
8.6
21
48
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.6
8.6
50
199
J01MA02
ATC
ciprofloxacin; systemic
1.4
8.6
565
4542
L08
ICD-10 Finland
Other local infections of skin and subcutaneous tissue
3.7
8.6
27
75
C07AA05
ATC
propranolol; systemic
1.6
8.6
202
1318
M48.0
ICD-10 Finland
Spinal stenosis
1.6
8.6
231
1557
N05BA04
ATC
oxazepam; oral
1.5
8.5
364
2706
J02AC01
ATC
fluconazole; systemic
1.5
8.5
390
2938
A69
ICPC
General and Unspecified, Other reason for encounter NEC
2.4
8.5
55
231
FP1C5
NOMESCO Finland
Resting ECG, 15 leads
3.7
8.5
26
71
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
8.5
722
6061
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
8.5
370
2761
R4150
NOMESCO Finland
Neuropsychological rehabilitation
90.6
8.4
9
*
RD211, ,
NOMESCO Finland
0.1
8.4
*
292
G46.7*I67.9
ICD-10 Finland
Other lacunar syndromes
+∞
8.3
8
*
WX725
NOMESCO Finland
Noninvasive ventilation
0.2
8.3
6
355
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
8.3
278
1965
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.6
8.3
173
2619
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
8.3
543
4357
B35.6
ICD-10 Finland
Tinea inguinalis [Tinea cruris]
3.2
8.2
31
97
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
2.6
8.2
47
186
SPAT1236
SPAT
Informing family of child’s disability
2.7
8.2
42
157
S00
ICD-10 Finland
Superficial injury of head
6.5
8.2
20
31
QAE99, ,
SPAT
3.9
8.2
23
59
Y94.8
ICD-10 Finland
Other leisure activity accident
2.7
8.2
44
169
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.1
8.2
33
108
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.9
8.2
101
548
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
8.1
125
726
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
8.1
467
3660
H53.4
ICD-10 Finland
Visual field defects
3.4
8.1
28
83
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
3.3
8.1
30
93
R11
ICD-10 Finland
Nausea and vomiting
1.8
8.1
133
788
S18
ICPC
Laceration/cut
1.4
8.1
627
5169
U02
ICPC
Urinary frequency/urgency
1.6
8.0
214
1438
B35.1
ICD-10 Finland
Tinea unguium
2.0
8.0
83
424
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.1
7.9
76
377
P70
ICPC
Dementia
2.1
7.9
76
377
K44
ICD-10 Finland
Diaphragmatic hernia
4.0
7.9
22
56
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
1.8
7.9
112
635
R25.2
ICD-10 Finland
Cramp and spasm
2.9
7.9
37
132
G21.8
ICD-10 Finland
Other secondary parkinsonism
13.1
7.9
13
10
F51
ICD-10 Finland
Nonorganic sleep disorders
3.0
7.8
34
116
S01
ICD-10 Finland
Open wound of head
3.5
7.8
26
75
PD5BD
NOMESCO Finland
Extensive CT of aorta
2.8
7.8
39
144
R23.3
ICD-10 Finland
Spontaneous ecchymoses
2.7
7.8
40
150
F01.29
ICD-10 Finland
Subcortical vascular dementia without information on additional symptoms
7.0
7.8
18
26
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
7.8
445
3480
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.9
7.7
96
521
F32.0
ICD-10 Finland
Mild depressive episode
3.2
7.7
30
96
C09DA01
ATC
losartan and diuretics; oral
1.6
7.7
167
1067
J01FA10
ATC
azithromycin; systemic
1.4
7.6
549
4458
M02AA07
ATC
piroxicam; topical
1.4
7.6
536
4338
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
7.6
133
803
HMAK, ,
NOMESCO Finland
0.3
7.6
22
681
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.2
7.6
62
289
Z25.1
ICD-10 Finland
Need for immunization against influenza
2.1
7.6
73
363
R47.0
ICD-10 Finland
Dysphasia and aphasia
6.2
7.5
19
31
G03DA02
ATC
medroxyprogesterone; systemic
1.7
7.5
126
750
H91.1
ICD-10 Finland
Presbycusis
1.6
7.5
172
1113
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.2
7.5
58
264
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
2.9
7.5
33
114
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
2.8
7.4
36
131
D64.8
ICD-10 Finland
Other specified anaemias
2.6
7.4
40
154
S00.9
ICD-10 Finland
Superficial injury of head, part unspecified
3.3
7.4
27
83
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.4
7.4
47
196
IGY99
NOMESCO Finland
Other psychiatric treatment contact
7.7
7.4
16
21
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
2.5
7.4
43
172
D07AA02
ATC
hydrocortisone; topical
1.6
7.4
162
1038
A08
ICPC
Swelling
1.8
7.4
101
567
H26.9
ICD-10 Finland
Cataract, unspecified
3.0
7.3
32
110
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
+∞
7.3
7
*
IER02
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, group
9.4
7.3
14
15
J01EA01
ATC
trimethoprim; systemic
1.4
7.3
404
3135
H53.8
ICD-10 Finland
Other visual disturbances
3.5
7.3
24
69
K02.0
ICD-10 Finland
Caries limited to enamel
1.7
7.3
123
735
X57
ICD-10 Finland
Unspecified privation
2.6
7.2
39
150
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
7.2
734
6272
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
15.8
7.2
11
7
UJF30, ,
SPAT
4.3
7.2
18
42
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.4
7.2
449
3554
WX290
NOMESCO Finland
Other blockage of nerve
1.4
7.2
343
2593
XCK00
NOMESCO Finland
Perimetry
1.8
7.1
111
648
H92.0
ICD-10 Finland
Otalgia
2.2
7.1
61
290
B01AC07
ATC
dipyridamole; systemic
1.9
7.1
82
435
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
0.6
7.1
104
1727
F51.9
ICD-10 Finland
Nonorganic sleep disorder, unspecified
4.1
7.1
19
47
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.1
7.1
19
47
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
6.1
7.1
18
30
H91.9
ICD-10 Finland
Hearing loss, unspecified
1.9
7.1
85
457
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.3
7.1
52
232
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
7.1
58
271
F01.3
ICD-10 Finland
Mixed cortical and subcortical vascular dementia
8.8
7.1
14
16
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
7.0
84
451
SPAT1222
SPAT
Counselling/guidance promoting independent living
0.6
7.0
140
2151
L01BC06
ATC
capecitabine; oral
0.2
7.0
5
302
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
1.8
7.0
97
547
Z5132
NOMESCO Finland
Nursing associate professional
4.4
7.0
17
39
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
6.9
102
585
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.7
6.9
36
136
L02
ICPC
Back symptom/complaint
1.8
6.9
109
638
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
6.9
99
564
U71
ICPC
Cystitis/urinary infection other
1.8
6.9
99
564
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
6.9
261
1887
M03BX02
ATC
tizanidine; oral
1.3
6.9
600
4998
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.2
6.9
56
261
I11
ICD-10 Finland
Hypertensive heart disease
3.5
6.9
23
67
W10
ICD-10 Finland
Fall on and from stairs and steps
2.0
6.8
76
398
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
6.8
333
2523
ZY000
NOMESCO Finland
Hospital inpatient
6.7
6.8
16
24
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.9
6.8
89
492
N28
ICPC
Limited function/disability (N)
2.9
6.8
31
109
5CM18, ,
NOMESCO Finland
11.0
6.8
12
11
R52.2
ICD-10 Finland
Other chronic pain
2.2
6.8
52
236
B01AB04
ATC
dalteparin; parenteral
1.9
6.8
82
442
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
2.8
6.8
32
115
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
2.4
6.8
45
192
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
6.8
183
1232
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
6.8
258
1867
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
40.2
6.8
8
*
R01AD09
ATC
mometasone; nasal
1.4
6.7
437
3473
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.3
6.7
24
73
SPAT1148
SPAT
Treatment of chronic ulcer or burn
0.6
6.7
108
1750
TQW40
NOMESCO Finland
Remowal of suture of skin
1.8
6.7
91
510
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.1
6.7
63
311
S42.2
ICD-10 Finland
Fracture of upper end of humerus
1.9
6.7
86
474
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
6.6
183
1238
F01
ICD-10 Finland
Vascular dementia
5.9
6.6
17
29
R23
ICD-10 Finland
Other skin changes
3.6
6.6
21
59
N06AB06
ATC
sertraline; oral
1.8
6.6
98
564
SFA30
NOMESCO Finland
Three-surface restoration
1.4
6.6
397
3115
R31
ICD-10 Finland
Unspecified haematuria
1.6
6.6
174
1165
U04
ICPC
Incontinence urine
1.7
6.6
111
663
UJH02
NOMESCO Finland
Anoscopy
2.1
6.6
58
279
TNH32
NOMESCO Finland
Custom moulded split, ankle or foot
4.2
6.6
17
41
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
2.5
6.6
40
164
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
10.1
6.5
12
12
E0000UV, ,
ATC
1.4
6.5
505
4121
SFA40
NOMESCO Finland
Restoration involving the entire crown of the tooth
1.5
6.5
251
1818
G45.3
ICD-10 Finland
Amaurosis fugax
2.7
6.5
33
123
AXX01, ,
SPAT
2.0
6.5
64
321
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
1.9
6.5
74
391
SPAT1370
SPAT
Other health check-up
0.2
6.5
7
322
A01
ICPC
Pain general/multiple sites
1.6
6.5
136
861
R60.9
ICD-10 Finland
Oedema, unspecified
1.8
6.5
91
515
FM1DE, ,
SPAT
5.3
6.5
18
34
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.0
6.4
68
350
XCH05
NOMESCO Finland
Eye pressure longterm registration
3.2
6.4
24
75
Z12.5
ICD-10 Finland
Special screening examination for neoplasm of prostate
3.4
6.4
22
65
P20
ICD-10 Finland
Intrauterine hypoxia
70.2
6.4
7
*
I68.0*E85.9
ICD-10 Finland
Cerebral amyloid angiopathy
70.2
6.4
7
*
F01.84
ICD-10 Finland
Other specified vascular dementia other mixed symptoms of mixed type
70.2
6.4
7
*
D02AX
ATC
Other emollients and protectives
2.4
6.4
41
172
G04BD07
ATC
tolterodine; oral
1.8
6.4
101
592
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
0.6
6.3
87
1473
A10AE04
ATC
insulin glargine; parenteral
1.6
6.3
134
851
C10AA07
ATC
rosuvastatin; oral
1.4
6.3
364
2833
A10AB05
ATC
insulin aspart; parenteral
1.7
6.3
105
625
R03AC02
ATC
salbutamol; inhalant
1.3
6.3
630
5332
H02AB02
ATC
dexamethasone; systemic
0.5
6.3
46
951
UDC00
NOMESCO Finland
Ear microscopy
0.4
6.3
25
663
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
6.3
210
1479
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.4
6.3
430
3441
R06AX27
ATC
desloratadine; oral
1.5
6.3
225
1608
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
+∞
6.3
6
*
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.7
6.2
115
704
K57
ICD-10 Finland
Diverticular disease of intestine
2.5
6.2
36
144
C08CA13
ATC
lercanidipine; oral
1.5
6.2
238
1722
N30.8
ICD-10 Finland
Other cystitis
3.7
6.2
19
52
B02
ICD-10 Finland
Zoster [herpes zoster]
2.0
6.2
68
355
L29.9
ICD-10 Finland
Pruritus, unspecified
2.4
6.2
41
175
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.0
6.2
17
43
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.2
436
3504
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
0.2
6.1
8
330
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.4
6.1
302
2289
Z00.8
ICD-10 Finland
Other general examinations
1.8
6.1
95
555
SXC03
NOMESCO Finland
Other oral or dental procedure
3.8
6.1
18
48
J01FA06
ATC
roxithromycin; oral
1.3
6.1
498
4089
G30
ICD-10 Finland
Alzheimer disease
2.4
6.1
39
164
S72.1
ICD-10 Finland
Pertrochanteric fracture
2.1
6.1
58
288
R21
ICPC
Throat symptom/complaint
1.6
6.1
149
981
B36.8
ICD-10 Finland
Other specified superficial mycoses
8.6
6.1
12
14
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
6.1
196
1371
H01.0
ICD-10 Finland
Blepharitis
2.0
6.0
65
337
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.8
6.0
92
534
N06AX03
ATC
mianserin; oral
1.9
6.0
68
359

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
838
2788
5.96
245.71
3.3
3.0
2.47
2.47
mmol/l
0.32
737
2416
818
2750
5.72
234.35
4.3
3.8
79.22
82.88
%
3.41
809
2676
686
2096
5.44
217.07
3.4
3.0
3.23
2.62
e6/l
0.62
287
1189
707
2243
5.33
213.01
3.3
2.9
1.33
1.34
e6/l
0.00
310
1324
859
3453
4.82
185.38
4.0
3.3
—
—
—
0
0
875
3647
4.70
177.84
4.0
3.3
0.52
0.55
e6/l
0.17
583
2849
961
4501
4.58
161.55
5.2
3.9
82.22
145.15
e6/l
1.93
610
3324
882
3990
4.24
152.92
4.1
3.4
44.81
82.97
e6/l
2.44
590
3130
1096
5801
5.02
152.35
3.1
2.2
91.71
92.65
pmol/l
0.30
584
2868
816
3526
4.13
150.43
1.9
1.6
19.73
20.20
nmol/l
0.43
768
2942
941
4558
4.21
145.38
2.8
3.3
2.37
2.36
mmol/l
4.31
852
3838
658
2652
3.78
129.88
4.7
4.3
243.06
267.40
ng/l
0.10
636
2368
1269
8185
6.61
120.96
36.0
24.5
328.61
329.98
g/l
6.59
1258
8090
1027
5746
3.92
117.86
4.1
4.2
34.84
34.27
g/l
2.71
964
5248
360
1031
4.35
114.17
2.3
2.3
30.90
38.68
u/l
1.56
302
851
635
2720
3.43
110.01
3.4
4.3
—
—
—
0
0
800
3986
3.33
106.98
3.2
3.8
7.40
7.40
ph
0.10
19
728
448
1698
3.40
91.97
2.1
1.8
30.28
30.24
s
0.05
440
1620
353
1165
3.71
89.70
4.7
5.2
1.46
1.41
mmol/l
0.36
342
1123
339
1097
3.75
88.62
5.3
6.1
—
—
—
0
0
861
4895
2.96
84.04
2.2
2.2
78.44
81.47
nmol/l
2.22
783
4162
584
2730
2.95
81.74
5.3
6.3
—
—
—
0
0
967
5969
2.98
78.85
5.7
5.5
1.21
1.21
mmol/l
1.34
921
5348
672
3519
2.74
73.92
2.3
2.0
268.10
224.26
u/l
0.60
633
3228
136
256
5.77
69.93
1.5
1.9
22.13
22.07
s
0.03
126
229
1060
7133
2.97
68.82
4.8
4.4
6.83
6.91
mmol/l
0.50
1006
6694
622
3231
2.66
68.14
1.6
1.8
906.52
1189.59
nmol/l
11.10
432
2369
1203
8736
3.60
67.37
34.9
21.3
14.24
15.58
%
37.90
1190
8557
1125
7876
3.14
66.76
5.0
4.5
—
—
—
0
0
212
605
3.95
65.27
2.5
3.1
23.96
24.14
mmol/l
0.30
201
587
1004
6701
2.74
63.69
5.7
6.3
1.22
1.22
mmol/l
0.10
948
5629
1273
9746
4.21
62.02
6.0
4.9
1.95
2.24
mu/l
1.55
1218
8556
218
657
3.74
61.90
5.9
7.3
24.23
24.62
mmol/l
0.92
206
620
548
2810
2.56
59.95
3.1
3.1
558.73
532.78
mosm/kgh2o
2.08
419
2401
781
4727
2.47
59.28
7.0
10.4
0.00
0.00
e9/l
0.72
518
3855
1125
8116
2.93
58.39
5.7
5.0
—
—
—
0
0
308
1245
2.89
53.31
2.2
2.4
8.20
10.31
umol/l
0.91
256
1075
735
4497
2.33
52.12
3.9
4.1
6.05
5.84
ph
0.53
22
135
89
154
6.10
49.72
1.2
1.4
58.97
720.43
e6/l
0.79
65
127
89
154
6.10
49.72
1.2
1.3
3.50
63.56
e6/l
0.93
62
123
529
2857
2.36
49.65
2.8
2.7
5.02
5.37
e6/l
0.41
446
2562
1177
8977
2.90
49.59
6.7
7.1
82.45
82.51
u/l
0.01
1115
8321
1310
10631
4.37
49.58
27.0
17.9
29.43
28.34
mg/l
0.65
1156
8844
145
392
4.01
47.67
3.7
3.4
—
—
—
0
0
282
1149
2.82
47.65
2.5
2.7
4.39
4.31
kpa
0.24
267
1108
314
1354
2.70
47.52
2.8
3.1
1.39
2.10
mmol/l
2.39
272
1105
316
1368
2.69
47.44
2.8
3.1
5.84
5.84
kpa
0.02
303
1319
56
60
9.68
47.38
1.2
1.3
—
—
—
0
0
638
3788
2.25
47.23
2.4
2.6
—
—
—
0
0
621
3662
2.25
46.57
2.6
2.3
2.65
3.19
mg/l
6.85
532
3065
757
4848
2.22
46.08
4.0
3.8
—
—
—
0
0
519
2872
2.28
45.11
2.3
2.5
—
—
—
0
0
761
4920
2.19
44.77
5.6
5.3
0.63
0.62
%
0.23
702
4498
83
149
5.86
44.61
1.2
1.3
3.85
3.87
mmol/l
0.05
72
138
1074
7999
2.45
44.53
4.0
3.9
14.85
15.31
pmol/l
7.12
991
6985
852
5773
2.21
44.32
2.8
3.0
51.59
56.95
u/l
0.93
768
5078
655
4025
2.17
43.46
5.4
4.0
—
—
—
0
0
907
6333
2.22
43.29
6.7
7.9
4.54
4.37
e9/l
1.16
670
5427
104
235
4.70
43.10
1.2
1.2
—
—
—
0
0
312
1403
2.57
42.95
2.8
3.1
—
7.39
—
0
6
799
5337
2.15
42.34
5.4
5.0
0.04
0.04
e9/l
0.09
568
4472
797
5324
2.15
42.15
5.4
5.0
0.66
0.63
e9/l
2.33
569
4450
766
5047
2.14
41.91
5.6
5.3
2.67
2.77
%
0.70
707
4611
765
5051
2.13
41.47
5.7
5.3
59.32
59.37
%
0.04
709
4621
1293
10691
3.58
41.28
19.3
17.7
—
—
—
0
0
766
5071
2.12
41.10
5.6
5.6
9.54
9.05
%
3.77
706
4636
74
129
6.00
40.97
1.1
1.2
—
—
—
0
0
712
4594
2.11
40.79
3.3
2.9
123.42
147.12
ug/l
1.97
673
4060
1255
10243
3.08
40.14
5.8
5.3
2.34
2.53
mmol/l
11.69
1180
8955
804
5452
2.11
40.08
5.4
5.1
2.17
1.78
e9/l
0.67
584
4686
1316
11056
3.94
39.75
12.2
11.0
22.26
22.68
u/l
0.51
1292
10481
808
5500
2.10
39.74
5.6
5.1
0.19
0.19
e9/l
0.56
588
4674
769
5160
2.08
39.06
5.7
5.5
24.40
25.15
%
0.95
710
4725
1325
11242
4.06
38.07
33.4
21.9
139.27
139.42
mmol/l
1.04
1312
10921
1325
11257
4.04
37.66
33.7
22.1
3.95
4.01
mmol/l
13.89
1311
10919
140
433
3.48
37.59
2.1
2.3
37.40
36.76
g/l
0.57
116
364
1330
11355
4.13
36.90
38.1
26.8
38.48
38.38
%
0.24
1290
10300
1330
11357
4.13
36.85
37.4
26.6
30.39
30.38
pg
0.11
1318
11094
1330
11357
4.13
36.85
37.4
26.7
234.04
238.19
e9/l
1.49
1288
10955
1330
11357
4.13
36.85
37.5
26.7
92.23
91.92
fl
1.55
1317
11093
1330
11357
4.13
36.85
37.5
26.7
7.29
7.00
e9/l
1.22
1290
10891
1330
11358
4.12
36.82
37.6
26.8
4.27
4.31
e12/l
1.50
1290
10903
1330
11358
4.12
36.82
37.8
27.0
127.52
129.84
g/l
6.79
1318
11098
1220
9934
2.72
36.82
7.2
6.7
41.83
41.42
mmol/mol
0.62
1160
8853
1244
10306
2.79
34.76
5.2
5.2
6.25
6.13
mmol/l
1.78
1153
8975
872
6304
2.01
33.97
4.1
5.7
12.80
12.46
umol/l
0.40
819
5950
423
2373
2.12
33.68
1.6
1.6
1.40
1.56
mg/l
0.53
312
1844
99
267
3.91
32.46
1.9
2.1
—
—
—
0
0
361
1937
2.16
32.03
2.2
2.6
0.80
0.82
mmol/l
1.85
312
1764
393
2183
2.11
31.85
3.2
3.5
0.77
0.85
ug/l
0.78
313
1598
308
1564
2.24
31.28
5.6
5.5
5.01
5.09
kpa
0.68
293
1472
1050
8225
2.09
31.26
4.0
4.1
15.73
16.06
mm/h
0.26
979
7367
306
1564
2.22
30.51
5.6
5.5
11.57
11.66
kpa
0.09
291
1473
307
1572
2.22
30.47
5.6
5.5
0.22
1.38
mmol/l
4.27
268
1199
144
517
2.99
30.05
2.1
2.4
3.06
3.12
g/l
0.36
120
449
787
5639
1.90
29.78
6.6
5.9
0.00
0.00
estimate
-0.00
23
1029
714
4980
1.88
29.16
5.0
5.7
—
—
—
0
0
175
711
2.67
28.92
5.0
6.2
24.92
24.95
mmol/l
0.03
175
704
100
297
3.55
28.46
1.2
1.2
—
—
—
0
0
789
5718
1.86
28.18
4.1
4.4
0.00
0.00
estimate
-0.00
24
1033
782
5673
1.85
27.61
4.1
4.4
0.06
0.00
estimate
0.45
33
1158
144
542
2.85
27.53
2.1
2.4
10.16
10.46
g/l
0.39
120
467
148
570
2.78
27.09
2.1
2.4
3.94
3.69
g/l
0.73
124
504
148
574
2.76
26.72
2.1
2.4
7.53
7.67
g/l
0.40
124
506
63
142
4.60
26.12
3.6
3.1
—
—
—
0
0
343
1934
2.02
25.97
2.5
2.5
19.37
20.88
%
1.27
326
1593
136
512
2.83
25.96
1.9
2.5
—
24.04
—
0
25
354
2040
1.98
25.09
2.3
2.4
2.19
2.25
g/l
1.40
335
1852
72
191
3.92
24.13
1.2
1.3
—
—
—
0
0
372
2219
1.92
23.62
2.3
2.5
10.52
11.45
umol/l
1.98
350
2015
39
63
6.34
23.26
1.1
1.2
—
—
—
0
0
38
60
6.48
23.16
1.1
1.0
245.96
306.74
ng/l
0.82
26
35
38
61
6.37
22.80
1.1
1.0
635.50
605.18
ng/l
0.16
26
34
47
96
5.03
21.91
3.9
3.4
319.86
338.11
umol/l
0.34
42
84
87
281
3.23
21.67
1.8
1.6
—
—
—
0
0
308
1782
1.93
21.15
2.0
2.3
1.75
1.80
%
0.38
259
1547
117
453
2.73
21.11
2.0
2.2
782.64
571.12
ug/l
0.20
111
423
281
1588
1.96
20.64
1.3
1.5
2.92
2.76
g/l
0.37
101
854
1156
9883
1.95
20.24
4.1
4.6
4.16
4.42
mmol/l
13.73
1063
8671
1141
9737
1.91
19.75
4.1
4.6
1.40
1.47
mmol/l
7.01
1034
8457
399
2609
1.74
18.00
1.4
1.6
1.29
1.27
mmol/l
0.16
387
2094
110
448
2.58
17.92
1.1
1.4
—
54.97
—
0
31
56
154
3.75
17.86
1.1
1.1
—
—
—
0
0
210
1129
2.01
17.59
3.0
3.2
90.58
97.04
ng/l
0.54
181
922
247
1406
1.92
17.52
6.4
5.7
94.78
95.40
%
0.59
242
1348
146
690
2.25
17.09
2.6
2.2
0.63
0.64
%
0.05
146
683
258
1521
1.85
16.33
2.8
3.2
303.06
263.27
ng/l
0.92
243
1390
225
1273
1.91
16.17
6.7
6.0
117.44
118.22
g/l
0.24
225
1232
809
6447
1.60
16.13
29.0
20.6
1.44
1.42
inr
0.11
63
1781
685
5304
1.57
15.05
2.5
2.7
—
—
—
0
0
143
706
2.14
14.98
2.6
2.2
1.12
1.10
%
0.15
143
700
48
1402
0.32
14.89
7.4
4.6
—
—
—
0
0
22
1003
0.21
14.72
3.9
4.7
—
—
—
0
0
149
758
2.08
14.42
1.6
1.6
—
—
—
0
0
1083
9387
1.67
14.25
3.6
4.1
1.19
1.24
mmol/l
1.88
954
8051
147
751
2.07
14.06
1.5
1.7
1.61
1.53
g/l
0.51
120
645
23
37
6.30
13.76
1.7
1.4
—
—
—
0
0
232
1398
1.79
13.49
1.8
1.7
—
—
—
0
0
440
3145
1.58
13.29
4.3
5.0
24.10
22.12
%
1.48
191
1735
576
4387
1.53
13.02
2.3
2.3
—
—
—
0
0
178
2924
0.55
12.31
5.5
4.2
—
—
—
0
0
282
1843
1.66
12.14
1.3
1.2
2.02
1.31
u/ml
0.44
39
431
35
92
3.88
11.95
1.6
1.4
11.21
10.09
%
0.64
35
92
268
3907
0.61
11.58
5.1
4.6
—
—
—
0
0
418
3048
1.53
11.19
2.5
2.8
5204.58
8947.14
umol/l
0.90
320
2517
201
1225
1.75
11.13
2.0
2.6
66.07
65.77
g/l
0.24
172
1078
513
3918
1.49
10.93
4.9
5.8
3.50
4.95
ug/l
0.56
454
3429
122
640
1.99
10.83
1.2
1.2
—
—
—
0
0
154
2542
0.56
10.62
3.3
3.5
—
—
—
0
0
261
1730
1.62
10.50
2.0
1.9
—
—
—
0
0
231
1485
1.66
10.49
1.3
1.3
—
—
—
0
0
28
71
4.00
10.06
4.5
3.1
—
—
—
0
0
29
884
0.31
9.66
4.7
3.7
0.50
0.66
%
—
8
321
210
3133
0.61
9.66
5.2
4.8
0.00
0.00
estimate
0.50
24
996
189
1177
1.70
9.64
1.4
1.4
—
—
—
0
0
245
1631
1.61
9.63
4.5
4.5
1.01
1.04
mmol/l
1.10
211
1480
413
3086
1.48
9.56
3.0
2.8
34.85
34.82
u/l
0.00
379
2885
27
70
3.91
9.43
1.0
1.1
5.29
3.03
u/ml
0.34
14
33
169
1028
1.73
9.38
2.2
2.4
—
—
—
0
0
215
3159
0.62
9.19
1.7
1.8
458.84
7794206.26
pmol/l
1.06
192
2502
129
735
1.83
8.93
1.5
1.4
—
—
—
0
0
74
350
2.18
8.67
12.6
13.5
—
—
—
0
0
50
200
2.56
8.54
1.7
2.1
26.73
33.48
umol/l
1.48
37
169
600
4896
1.39
8.27
3.0
3.3
2862.22
2033.82
ng/l
1.86
530
4268
71
340
2.15
8.08
1.1
1.0
—
2.15
—
0
6
33
109
3.08
8.04
1.0
1.1
—
—
—
0
0
176
1147
1.61
7.48
4.6
5.4
11.48
12.17
mmol/l
0.48
163
1072
5
308
0.16
7.35
2.0
4.9
5.04
5.01
kpa
—
5
301
5
309
0.16
7.34
2.0
4.9
9.94
8.19
kpa
—
5
302
147
920
1.67
7.33
1.9
1.8
129.35
152.85
ug/g
0.51
123
692
41
936
0.42
7.27
4.8
3.9
0.00
0.11
%
—
9
327
45
187
2.45
7.14
1.4
1.4
—
—
—
0
0
46
986
0.45
6.94
4.6
3.8
0.50
0.81
%
0.94
14
376
38
864
0.42
6.68
5.0
3.8
0.00
0.48
%
—
5
263
123
763
1.67
6.35
2.2
2.6
—
—
—
0
0
78
424
1.89
6.31
1.4
1.2
—
—
—
0
0
112
683
1.70
6.17
7.5
7.3
—
—
—
0
0
107
646
1.71
6.12
1.6
1.4
—
—
—
0
0
89
510
1.80
6.10
1.2
1.2
—
—
—
0
0
98
584
1.73
5.88
2.3
2.8
—
—
—
0
0
15
26
5.82
5.84
2.6
1.9
48.70
47.47
umol/l
—
10
19
47
226
2.12
5.39
1.3
1.5
—
—
—
0
0
57
295
1.97
5.36
1.3
1.3
55.13
59.20
mmol/l
0.42
45
236
28
651
0.42
5.24
3.4
3.3
4.61
5.57
e9/l
0.39
21
448
46
223
2.10
5.17
1.3
1.1
—
—
—
0
0
188
1361
1.44
4.86
1.8
2.5
4.61
5.36
ug/l
0.61
153
1125
199
1463
1.42
4.73
1.4
1.4
—
—
—
0
0
83
505
1.68
4.67
2.7
2.9
4.11
4.29
pmol/l
1.11
68
425
24
93
2.61
4.48
1.7
1.4
—
—
—
0
0
311
2477
1.33
4.48
1.2
1.3
—
—
—
0
0
54
294
1.87
4.43
1.4
1.6
20425.33
18164.20
e6/l
0.10
30
205
6
239
0.25
4.36
1.8
1.9
1.30
1.67
mmol/l
—
6
231
7
257
0.27
4.30
4.3
1.8
—
—
—
0
0
30
133
2.28
4.24
1.1
1.2
285.63
289.87
nmol/l
0.04
30
99
198
1484
1.39
4.21
1.3
1.2
50.72
42.78
iu/ml
0.23
41
459
15
46
3.29
4.19
1.2
1.3
1721.13
1656.15
ml
0.12
15
41
79
489
1.65
4.19
3.9
3.2
0.73
0.83
nmol/l
1.05
70
377
60
345
1.77
4.15
1.5
1.5
235.64
263.55
ug/g
0.52
33
214
102
674
1.55
4.14
1.5
1.4
—
—
—
0
0
151
1104
1.41
3.72
1.3
1.3
462.50
508.29
titre
0.17
32
263
34
168
2.05
3.72
1.5
1.5
—
—
—
0
0
15
50
3.02
3.69
1.3
1.1
—
—
—
0
0
56
913
0.60
3.57
3.3
3.6
—
—
—
0
0
11
27
4.10
3.39
1.1
1.1
—
—
—
0
0
23
104
2.23
3.16
1.3
1.1
27.53
36.05
mmol/l
1.18
15
90
75
498
1.53
3.04
2.1
2.9
248.36
4724.33
u/ml
1.18
59
421
33
177
1.89
2.92
1.4
1.5
—
—
—
0
0
12
39
3.09
2.77
1.3
1.6
—
—
—
0
0
13
48
2.72
2.72
1.5
1.5
34.83
107.11
umol/l
—
6
36
35
197
1.80
2.69
1.4
1.4
93994.95
53201.77
e6/l
0.18
21
119
22
106
2.09
2.63
1.2
1.1
—
42.15
—
0
6
13
49
2.67
2.62
1.0
1.1
139.62
132.17
nmol/l
0.12
13
49
5
7
7.16
2.55
2.2
2.0
18.98
16.70
umol/l
—
5
7
124
945
1.34
2.43
1.7
2.0
420.59
390.62
nmol/l
0.77
105
841
5
8
6.27
2.37
1.2
1.1
—
—
—
0
0
9
216
0.41
2.32
3.4
2.6
—
—
—
0
0
22
112
1.98
2.31
1.3
1.1
—
—
—
0
0
36
218
1.67
2.20
1.4
1.4
1852.68
1677.10
e6/l
0.08
22
161
26
143
1.83
2.19
1.2
1.2
267.73
273.47
mosm/kgh2o
0.49
15
97
6
164
0.36
2.15
1.5
1.4
—
—
—
0
0
32
190
1.70
2.11
1.4
1.6
—
—
—
0
0
21
109
1.94
2.11
1.6
2.3
492.87
602.83
ml
0.73
16
63
83
609
1.39
2.09
1.3
1.3
—
—
—
0
0
5
10
5.01
2.07
1.2
1.0
—
—
—
0
0
185
1523
1.25
2.04
2.6
3.8
2.94
29.18
ug/l
3.69
146
1278
167
1362
1.26
2.00
1.2
1.2
3.26
16.03
u/ml
5.05
36
440
166
1354
1.26
1.99
2.2
2.4
67.28
67.48
e9/l
0.03
73
1052
40
603
0.65
1.93
5.7
3.8
—
—
—
0
0
17
318
0.53
1.89
4.4
3.8
—
—
—
0
0
14
278
0.50
1.88
2.9
3.0
28.76
1545.91
u/ml
0.97
14
253
6
17
3.54
1.84
1.3
1.2
—
—
—
0
0
19
101
1.89
1.81
1.1
1.1
249.91
322.08
u/ml
0.53
11
51
9
35
2.58
1.80
1.0
1.1
—
—
—
0
0
6
18
3.34
1.74
1.0
1.1
—
—
—
0
0
0
47
0.00
1.70
0.0
1.3
—
646.62
—
0
25
6
145
0.41
1.65
4.2
3.0
—
—
—
0
0
43
294
1.48
1.64
1.2
1.2
0.23
0.86
u/ml
—
8
27
21
120
1.76
1.62
1.0
1.0
—
—
—
0
0
13
248
0.52
1.58
1.1
1.3
—
—
—
0
0
142
1173
1.23
1.56
2.0
1.9
0.21
0.19
g/l
1.42
125
1075
20
115
1.75
1.53
1.1
1.1
—
—
—
0
0
0
45
0.00
1.50
0.0
2.7
—
1731.53
—
0
36
6
22
2.73
1.43
1.0
1.1
—
—
—
0
0
7
154
0.45
1.43
3.1
4.6
—
—
—
0
0
7
29
2.42
1.39
1.1
1.2
206.65
140.16
mmol/24h
—
7
29
49
356
1.39
1.39
1.0
1.1
—
163.00
—
0
5
8
161
0.49
1.36
1.3
2.1
—
—
—
0
0
5
17
2.95
1.36
1.2
1.0
2525.00
1333.82
miu/ml
—
5
17
10
196
0.51
1.35
1.9
2.4
—
—
—
0
0
34
232
1.48
1.35
1.2
1.1
—
498.57
—
0
7
75
586
1.30
1.33
5.7
3.9
—
—
—
0
0
86
686
1.27
1.31
2.0
2.8
10.97
10.87
g/l
0.07
78
609
11
55
2.01
1.27
1.5
1.5
—
—
—
0
0
36
253
1.43
1.25
1.3
1.5
28.64
30.03
g/l
0.28
29
236
33
228
1.46
1.25
2.5
2.3
—
—
—
0
0
22
139
1.59
1.23
1.2
1.1
—
—
—
0
0
33
466
0.70
1.22
3.0
2.7
0.47
0.32
g/l
0.49
15
165
33
230
1.45
1.20
2.5
2.3
107.30
105.36
mmol/l
1.07
33
225
33
230
1.45
1.20
2.5
2.3
4.03
4.12
mmol/l
0.74
33
225
6
26
2.31
1.18
1.0
1.0
—
—
—
0
0
132
1118
1.20
1.18
1.4
1.3
—
—
—
0
0
0
33
0.00
1.16
0.0
1.2
—
—
—
0
0
65
510
1.29
1.15
3.3
3.2
60.61
70.56
mg/l
0.11
55
419
8
40
2.01
1.12
1.1
1.0
—
6.77
—
0
9
34
243
1.41
1.10
1.4
1.4
—
—
—
0
0
19
121
1.58
1.05
1.2
1.2
—
—
—
0
0
38
509
0.74
1.05
2.5
2.2
—
—
—
0
0
7
34
2.06
1.03
2.0
1.2
—
—
—
0
0
64
511
1.26
1.01
3.4
3.2
40.51
186.89
mg/l
0.73
54
415
28
197
1.43
1.00
1.6
1.5
4.37
5.74
iu/l
—
6
59
9
158
0.57
0.98
3.7
1.5
—
—
—
0
0
5
23
2.18
0.98
1.8
1.5
0.16
0.09
nmol/l
—
5
16
9
161
0.56
0.98
1.6
1.2
—
—
—
0
0
0
29
0.00
0.97
0.0
1.9
—
2.61
—
0
9
7
36
1.95
0.97
2.0
3.2
—
—
—
0
0
0
31
0.00
0.96
0.0
2.1
—
—
—
0
0
0
31
0.00
0.96
0.0
1.1
—
1.61
—
0
18
42
320
1.32
0.95
1.8
2.2
42.63
79.52
ug/min
1.19
29
180
6
29
2.07
0.89
2.0
1.8
—
—
—
0
0
5
103
0.48
0.89
4.4
3.8
454.58
35.98
mg/l
—
5
86
6
30
2.00
0.87
1.0
1.2
—
—
—
0
0
6
30
2.00
0.87
1.0
1.2
—
—
—
0
0
49
388
1.27
0.86
3.5
3.3
8.04
7.81
mmol/l
0.21
49
379
8
44
1.82
0.86
1.0
1.0
—
—
—
0
0
6
31
1.94
0.84
1.0
1.2
—
—
—
0
0
6
31
1.94
0.84
1.0
1.2
—
—
—
0
0
6
31
1.94
0.84
1.0
1.2
—
—
—
0
0
0
24
0.00
0.79
0.0
2.0
—
—
—
0
0
0
25
0.00
0.79
0.0
1.2
—
21.47
—
0
17
0
27
0.00
0.77
0.0
1.5
—
30.72
—
0
18
0
27
0.00
0.77
0.0
1.1
—
172.60
—
0
27
6
34
1.77
0.76
1.0
1.4
0.93
0.96
g/l
—
6
34
6
34
1.77
0.76
1.3
1.4
—
—
—
0
0
7
38
1.85
0.73
2.6
1.7
9.06
8.77
nmol/l
—
7
29
50
407
1.24
0.72
3.4
3.3
1.67
1.72
mmol/l
0.09
50
398
6
107
0.56
0.72
1.7
1.8
—
—
—
0
0
9
56
1.61
0.72
1.2
1.1
11.72
9.67
mmol/l
—
9
50
5
26
1.93
0.70
1.2
1.2
—
—
—
0
0
15
101
1.49
0.70
1.7
1.6
—
—
—
0
0
5
27
1.85
0.68
1.0
1.5
1.59
1.54
g/l
—
5
27
7
42
1.67
0.68
1.1
1.2
—
—
—
0
0
94
821
1.16
0.66
5.0
4.1
—
—
—
0
0
10
62
1.62
0.65
1.0
1.3
—
—
—
0
0
6
103
0.58
0.62
1.8
3.1
7.75
7.14
mmol/l
—
6
69
6
103
0.58
0.62
2.7
3.1
—
—
—
0
0
63
536
1.18
0.61
2.2
2.2
13.28
11.22
nmol/l
0.71
51
450
8
51
1.57
0.60
1.0
1.1
88.50
369.18
u/l
—
8
45
17
123
1.39
0.58
1.4
1.2
—
—
—
0
0
48
401
1.20
0.58
1.1
1.2
235.42
193.16
u/ml
0.16
43
366
13
182
0.71
0.54
1.3
1.4
128.23
365.14
pmol/l
1.82
13
177
32
391
0.81
0.51
3.5
3.2
—
—
—
0
0
50
427
1.18
0.49
1.1
1.2
191.63
131.02
iu/ml
—
8
142
12
84
1.43
0.49
1.1
1.1
—
—
—
0
0
82
921
0.88
0.49
8.0
5.5
24.84
24.47
mmol/l
0.31
82
875
10
144
0.69
0.49
3.1
2.3
8.20
2.30
u/field
—
5
43
7
46
1.52
0.48
2.3
2.3
—
—
—
0
0
71
796
0.89
0.43
2.0
1.5
—
—
—
0
0
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
6.7
—
—
—
0
0
0
17
0.00
0.40
0.0
1.8
—
35.12
—
0
17
0
18
0.00
0.40
0.0
1.0
—
8.75
—
0
8
393
3779
1.06
0.39
2.7
3.1
82.43
278.21
mg/l
2.63
257
2402
10
137
0.73
0.39
1.3
1.5
—
—
—
0
0
15
115
1.31
0.39
1.1
1.2
—
—
—
0
0
5
36
1.39
0.38
1.4
1.8
—
—
—
0
0
59
527
1.12
0.35
4.6
3.3
1.74
1.40
mmol/l
0.57
59
520
6
42
1.43
0.35
1.2
1.0
—
—
—
0
0
5
79
0.63
0.35
1.0
1.1
—
—
—
0
0
102
1106
0.92
0.35
3.9
3.7
—
—
—
0
0
23
276
0.83
0.34
5.3
2.8
—
—
—
0
0
54
481
1.13
0.34
6.2
5.1
—
—
—
0
0
6
45
1.33
0.33
1.2
1.0
—
—
—
0
0
31
352
0.88
0.26
2.6
3.0
—
—
—
0
0
20
235
0.85
0.26
1.1
1.1
—
—
—
0
0
533
5215
1.04
0.25
4.5
4.4
62.42
61.85
ng/l
0.01
342
4142
12
96
1.25
0.24
1.2
1.7
3.52
4.94
mg/l
1.60
12
90
10
79
1.27
0.22
1.5
2.3
—
42.40
—
0
6
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
3.0
—
88.55
—
0
6
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
7.1
—
—
—
0
0
85
801
1.07
0.20
1.4
1.4
—
—
—
0
0
6
49
1.23
0.20
2.3
1.4
67.00
53.81
ug/l
—
6
44
16
186
0.86
0.19
1.8
1.6
5.52
4.20
mmol/24h
0.60
11
155
16
137
1.17
0.19
1.3
1.2
—
—
—
0
0
11
132
0.83
0.18
1.2
1.3
13.09
16.35
u/l
0.24
11
121
367
3750
0.97
0.18
2.3
2.4
60.17
81.81
u/l
0.49
336
3415
11
131
0.84
0.17
1.1
1.1
—
—
—
0
0
7
63
1.11
0.17
1.0
1.0
—
—
—
0
0
5
70
0.71
0.16
4.6
1.6
1.20
2.42
u/field
—
5
50
55
515
1.07
0.16
1.3
1.3
—
—
—
0
0
35
323
1.09
0.14
2.4
2.2
135.00
124.66
g/l
1.33
16
237
39
363
1.08
0.14
1.4
1.5
—
—
—
0
0
11
128
0.86
0.13
1.2
1.2
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
—
—
—
0
0
5
45
1.11
0.09
1.0
1.0
—
—
—
0
0
382
3772
1.02
0.09
2.7
3.0
6.42
6.59
mmol/l
0.33
310
3039
60
622
0.96
0.08
1.8
1.7
0.93
2.87
ug/l
1.72
51
531
8
74
1.08
0.07
1.1
1.1
—
—
—
0
0
10
89
1.12
0.07
1.4
1.3
12.43
9.17
u/l
—
5
68
10
89
1.12
0.07
1.7
2.0
1.39
1.79
ug/l
—
10
72
100
977
1.03
0.06
4.4
3.7
—
—
—
0
0
12
109
1.10
0.06
2.3
1.7
—
—
—
0
0
12
110
1.09
0.05
1.0
1.3
—
—
—
0
0
10
91
1.10
0.04
1.7
2.0
2.23
3.07
ug/l
—
10
80
11
118
0.93
0.02
1.5
1.2
—
—
nmol/l
—
0
0
15
142
1.06
0.02
1.0
1.1
—
—
—
0
0
103
1021
1.01
0.01
1.3
1.4
—
—
—
0
0
18
186
0.97
0.00
1.1
1.4
—
—
—
0
0
256
2556
1.00
0.00
5.2
4.9
1.01
1.02
kg/l
4.65
59
416
10
103
0.97
0.00
1.2
1.1
1.40
1.67
g/l
—
10
91
13
133
0.98
0.00
1.9
1.7
—
—
—
0
0
403
4035
1.00
0.00
3.5
3.7
14.24
9.06
mg/mmol
0.80
249
2506
27
275
0.98
0.00
1.2
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
5
57
0.88
0.00
4.2
4.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
1.42
—
0
6
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
11.8
—
—
—
0
0
7
71
0.99
-0.00
2.6
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
51
0.98
-0.00
9.6
5.6
—
—
—
0
0
8
82
0.98
-0.00
2.3
2.5
—
—
—
0
0
9
97
0.93
-0.00
1.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint I9_PROGVASC and mortality.

Females

Parameter HR [95% CI] p-value
I9_PROGVASC 1.801 [1.51, 2.14] < 0.001
Birth year 0.998 [0.99, 1.01] 0.614

During the follow-up period (1.1.1998 — 31.12.2019), 1426 out of 3641 females with I9_PROGVASC died.

Males

Parameter HR [95% CI] p-value
I9_PROGVASC 2.237 [1.78, 2.82] < 0.001
Birth year 0.984 [0.98, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1110 out of 2445 males with I9_PROGVASC died.

Mortality risk

Mortality risk for people of age

years, who have I9_PROGVASC.

N-year risk Females Males
1 0.181% 0.372%
5 1.113% 2.372%
10 2.898% 6.012%
15 5.374% 11.12%
20 9.441% 18.33%

Relationships between endpoints

↥

Index endpoint: I9_PROGVASC – Progressive vascular leukoencephalopathy

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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