Ulcerative proctitis

ULCERPROCT

proctitis: An inflammatory process affecting the anus. It is usually caused by sexually transmitted infectious agents and/or inflammatory bowel disease.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K51.2
  • Cause of death: ICD-10 K51.2

2 out of 7 registries used, show all original rules.

2500

4. Check minimum number of events

None

2500

5. Include endpoints

None

2500

6. Filter based on genotype QC (FinnGen only)

2500

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K51
Name in latin
Proctitis ulcerosa [chronica]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 13877 7303 6509
Only index persons 13418 7120 6298
Unadjusted period prevalence (%)
Whole population 0.20 0.21 0.18
Only index persons 0.25 0.26 0.24
Median age at first event (years)
Whole population 42.59 40.72 44.56
Only index persons 42.09 40.47 43.93

-FinnGen-

Key figures

All Female Male
Number of individuals 2500 1434 1066
Unadjusted period prevalence (%) 0.48 0.49 0.47
Median age at first event (years) 43.48 39.61 48.68

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2240
Matched controls
22398
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K51.5
ICD-10 Finland
Left sided colitis
4263.7
323.0
907
*
K51
ICD-10 Finland
Ulcerative colitis
3656.6
323.0
326
*
A07EA06
ATC
budesonide; oral, local oral
320.8
323.0
830
41
UJF30
NOMESCO Finland
Ileoscopy through colon
17.2
323.0
814
718
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
323.0
914
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3758.8
323.0
966
*
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
+∞
323.0
2240
7
L04AX01
ATC
azathioprine; systemic
47.6
323.0
673
200
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
15.8
323.0
725
657
A07EC02
ATC
mesalazine; oral, rectal
2679.7
323.0
2046
88
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
323.0
1844
*
UJF32
NOMESCO Finland
Coloscopy
21.1
323.0
1637
2557
A07EA02
ATC
hydrocortisone; rectal
730.9
323.0
1108
30
K51.8
ICD-10 Finland
Other ulcerative colitis
2532.2
323.0
390
*
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
321.8
301
*
H02AB06
ATC
prednisolone; systemic
5.6
305.6
1575
6682
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
257.3
242
*
A07EC01
ATC
sulfasalazine; oral, rectal
9.0
227.1
525
735
A07EA01
ATC
prednisolone; rectal
609.8
226.7
221
*
L01BB02
ATC
mercaptopurine; oral
166.5
216.1
225
15
D94
ICPC
Chronic enteritis/ulcerative colitis
257.7
186.6
189
8
H02AB07
ATC
prednisone; oral
5.3
167.0
592
1429
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
158.2
150
*
K50.9
ICD-10 Finland
Crohn disease, unspecified
1588.4
151.8
146
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
29.8
146.1
199
73
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.5
135.3
836
3281
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
56.9
130.0
154
29
K50.1
ICD-10 Finland
Crohn disease of large intestine
+∞
126.2
120
*
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
197.0
126.0
130
7
K50.8
ICD-10 Finland
Other Crohn disease
+∞
125.2
119
*
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
33.2
117.2
155
50
A07EC03
ATC
olsalazine; oral
+∞
102.9
98
*
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
46.1
89.6
110
25
J01MA02
ATC
ciprofloxacin; systemic
2.6
89.0
968
5133
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
87.0
83
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.7
79.2
704
3279
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
6.1
79.0
228
406
ZX120
NOMESCO Finland
Intravenous
4.3
78.8
319
827
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
78.6
75
*
A06AC01
ATC
ispaghula (psylla seeds); oral
2.8
78.1
612
2638
K50.0
ICD-10 Finland
Crohn disease of small intestine
763.2
75.7
74
*
P01AB01
ATC
metronidazole; oral, rectal
2.3
71.6
996
5795
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
65.9
63
*
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
582.6
57.9
57
*
C05AA08
ATC
fluocortolone; rectal, topical
2.9
57.1
406
1606
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
+∞
56.5
54
*
4AA12
NOMESCO Finland
NA
288.5
55.4
56
*
WX002
NOMESCO Finland
Sedation and analgesia
2.6
55.4
482
2147
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
55.1
517
2401
D16
ICPC
Rectal bleeding
8.3
47.4
108
136
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
104.3
46.9
51
5
A02BC02
ATC
pantoprazole; systemic
1.9
46.9
1381
10216
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
44.9
43
*
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
43.9
42
*
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
32.4
43.4
57
18
L04AB04
ATC
adalimumab; parenteral
7.7
43.0
102
137
4AB02
NOMESCO Finland
NA
153.0
42.9
45
*
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
42.8
41
*
K92.1
ICD-10 Finland
Melaena
4.7
42.5
151
338
UJF92
NOMESCO Finland
Capsular endoscopy
8.6
41.0
91
110
JFH10
NOMESCO Finland
Total colectomy and ileostomy
54.4
40.6
48
9
UJG02
NOMESCO Finland
Proctoscopy
6.7
39.1
103
161
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
39.1
435
2157
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
+∞
37.6
36
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
36.2
498
2704
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
32.6
795
5279
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
32.6
832
5608
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.2
30.6
122
306
A02BC05
ATC
esomeprazole; systemic
1.7
29.2
820
5635
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
295.6
28.8
29
*
UJH02
NOMESCO Finland
Anoscopy
3.9
28.5
121
322
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.3
28.3
88
171
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
27.8
245
1070
N02BE01
ATC
paracetamol; systemic, rectal
1.8
27.2
1823
15862
A02BC03
ATC
lansoprazole; oral
1.8
26.8
563
3516
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
274.2
26.8
27
*
253
Kela drug reimbursment
NA
+∞
26.1
25
*
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
26.1
25
*
3042
Kela drug reimbursment
NA
+∞
26.1
25
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.2
25.9
297
1470
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.7
25.6
185
721
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.5
25.5
77
145
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
20.9
25.2
37
18
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.7
25.2
114
321
Z93.2
ICD-10 Finland
Ileostomy status
21.5
24.8
36
17
J01DB01
ATC
cefalexin; oral
1.7
24.2
1780
15522
A07DA03
ATC
loperamide; oral
4.1
24.1
95
237
A06AC51
ATC
ispaghula, combinations; systemic
3.3
22.4
119
380
L04AB06
ATC
golimumab; parenteral
8.9
22.1
47
54
JFF10
NOMESCO Finland
Loop enterostomy
13.9
21.8
37
27
L04AC05
ATC
ustekinumab; parenteral
22.4
21.7
31
14
C10AC01
ATC
colestyramine; oral
4.9
21.6
71
148
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
13.5
21.0
36
27
D18
ICPC
Change in faeces/bowel movements
5.0
20.4
66
135
UJF34
NOMESCO Finland
Left colonoscopy
10.7
20.4
39
37
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.9
20.4
125
442
A02BC01
ATC
omeprazole; systemic
1.7
20.3
523
3436
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.3
20.2
194
881
N02AX02
ATC
tramadol; systemic, rectal
1.6
20.2
783
5716
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.8
19.9
129
471
56902
ICD-8 Finland
Other diseases of intestines and peritoneum, Proctitis haemorrhagica (ulcerosa)
+∞
19.8
19
*
L04AD01
ATC
ciclosporin; systemic
4.6
19.5
68
151
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
19.4
1554
13339
K61.0
ICD-10 Finland
Anal abscess
5.0
19.1
62
128
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
18.6
762
5613
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.6
18.6
143
577
A07AA09
ATC
vancomycin; oral
6.5
17.8
46
72
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
17.7
17
*
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
17.7
17
*
K50
ICD-10 Finland
Crohn disease [regional enteritis]
95.8
17.6
19
*
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.7
17.5
123
471
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
5.6
16.9
49
89
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
16.5
251
1382
D11
ICPC
Diarrhoea
1.9
16.4
254
1409
K59.1
ICD-10 Finland
Functional diarrhoea
2.9
16.1
102
368
H02AB09
ATC
hydrocortisone; systemic
3.8
15.8
67
180
A02BA02
ATC
ranitidine; systemic
1.7
15.8
335
2062
H02AB04
ATC
methylprednisolone; systemic
1.8
15.7
276
1599
JHA00
NOMESCO Finland
Anal or perianal incision
5.0
15.4
49
100
3AC01
NOMESCO Finland
NA
6.3
15.3
40
64
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
15.2
460
3119
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
15.2
350
2204
K83.0
ICD-10 Finland
Cholangitis
6.2
15.0
40
66
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.1
14.8
182
923
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
14.6
14
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.8
14.4
94
348
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.4
14.2
122
524
K60.3
ICD-10 Finland
Anal fistula
4.1
14.1
54
133
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
14.1
254
1485
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.6
14.0
62
174
D06BX01
ATC
metronidazole; topical
1.9
13.9
215
1193
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
13.8
909
7264
SPAT1263
SPAT
Sampling
1.4
13.8
835
6569
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
23.9
13.8
19
8
J05AB01
ATC
aciclovir; systemic
1.6
13.7
402
2701
4AA33
NOMESCO Finland
NA
+∞
13.6
13
*
K52.1
ICD-10 Finland
Toxic gastroenteritis and colitis
+∞
13.6
13
*
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
5.0
13.5
43
88
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
13.5
181
953
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
4.2
13.5
51
125
J01MA12
ATC
levofloxacin; systemic
1.7
13.4
319
2027
1490
FHL
Sigmoideoscopy (fiberscope)
18.3
13.4
20
11
1370
FHL
Colonoscopy, whole colon
11.5
13.3
24
21
TJF80
NOMESCO Finland
Ostomy education
6.7
13.3
33
50
C05AA01
ATC
hydrocortisone; rectal, topical
2.5
13.1
105
437
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
4.4
13.0
46
106
N03AX12
ATC
gabapentin; oral
1.7
12.7
278
1723
L04AA33
ATC
vedolizumab; parenteral
+∞
12.5
12
*
D07AC01
ATC
betamethasone; topical
1.4
12.4
625
4727
JAH00
NOMESCO Finland
Laparotomy
3.3
12.2
61
190
JFF13
NOMESCO Finland
Terminal enterostomy
21.4
12.0
17
8
R01AD09
ATC
mometasone; nasal
1.4
11.9
924
7543
J01FA10
ATC
azithromycin; systemic
1.4
11.8
1218
10421
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
4.8
11.8
38
80
UJF30
SPAT
NA
10.6
11.7
22
21
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
11.7
1373
11992
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.9
11.7
180
996
B01AB05
ATC
enoxaparin; parenteral
1.5
11.7
511
3743
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
12.6
11.6
20
16
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
11.6
1140
9666
N05CF01
ATC
zopiclone; oral
1.5
11.6
543
4035
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.6
11.6
81
314
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
11.5
173
947
K30
ICD-10 Finland
Functional dyspepsia
1.8
11.5
193
1101
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
120.6
11.4
12
*
D99
ICPC
Disease digestive system other
6.7
11.4
28
42
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.5
11.4
91
380
Z01.2
ICD-10 Finland
Dental examination
1.4
11.3
831
6701
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
11.2
123
595
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
11.2
938
7729
R06.0
ICD-10 Finland
Dyspnoea
1.5
11.2
396
2771
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
11.2
504
3713
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
2.9
11.1
66
232
KMAK
NOMESCO Finland
NA
1.4
11.0
1113
9451
R03AC02
ATC
salbutamol; inhalant
1.4
10.9
1033
8669
D01
ICPC
Abdominal pain/cramps general
1.8
10.8
203
1199
A03CA02
ATC
clidinium and psycholeptics; oral
2.3
10.7
95
419
UKC02
NOMESCO Finland
Cystoscopy
1.7
10.6
239
1488
J02AC01
ATC
fluconazole; systemic
1.4
10.6
790
6365
K62.7
ICD-10 Finland
Radiation proctitis
11.3
10.5
19
17
JHD00
NOMESCO Finland
Anal dilatation
6.6
10.5
26
40
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
+∞
10.4
10
*
J05AB11
ATC
valaciclovir; oral
1.7
10.4
242
1523
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
10.2
287
1898
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
10.2
194
1151
N03AX16
ATC
pregabalin; oral
1.5
10.1
397
2836
A05AA02
ATC
ursodeoxycholic acid; oral
3.7
10.1
43
119
3005
Kela drug reimbursment
Tofacitinib
14.6
10.0
16
11
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.9
9.8
132
698
R50.9
ICD-10 Finland
Fever, unspecified
1.6
9.8
251
1622
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.7
9.8
190
1134
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
9.6
9.8
19
20
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
9.6
319
2193
J31.0
ICD-10 Finland
Chronic rhinitis
1.9
9.6
146
807
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.5
987
8339
ZXC86
NOMESCO Finland
Use of endoscopic device
7.2
9.5
22
31
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
9.4
384
2761
UJF32
SPAT
NA
3.7
9.4
39
106
UJD02
NOMESCO Finland
Gastroscopy
2.3
9.4
86
386
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
9.4
9
*
R51.80
ICD-10 Finland
Headache
1.6
9.3
283
1908
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.2
9.2
47
150
SPAT1262
SPAT
Handing over of treatment supplies
1.5
9.2
302
2070
S18
ICPC
Laceration/cut
1.4
9.2
707
5699
K62.9
ICD-10 Finland
Disease of anus and rectum, unspecified
6.7
9.1
22
33
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
9.1
615
4850
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
9.1
305
2103
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
9.0
1070
9191
J01CA04
ATC
amoxicillin; systemic
1.4
9.0
1703
15664
-1
NOMESCO Finland
NA
1.4
9.0
682
5482
K56.7
ICD-10 Finland
Ileus, unspecified
4.5
9.0
30
67
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
3.4
8.9
41
122
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
12.6
8.9
15
12
Z43.2
ICD-10 Finland
Attention to ileostomy
12.6
8.9
15
12
L04AA01
ATC
[U] ciclosporin; systemic
3.5
8.8
39
112
JF2AB
NOMESCO Finland
Colongraphy with X-ray
10.7
8.8
16
15
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
8.8
637
5077
XJH00
NOMESCO Finland
Transanal ultrasonography
2.2
8.7
89
420
M05BA04
ATC
alendronic acid; oral
2.1
8.7
94
456
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
50.2
8.7
10
*
B80
ICPC
Iron deficiency anaemia
3.3
8.7
42
130
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
4.1
8.7
32
79
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
8.6
797
6593
JG1JB
NOMESCO Finland
Defekography with X-ray
5.5
8.6
24
44
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
8.6
124
672
M54.5
ICD-10 Finland
Low back pain
1.4
8.6
606
4810
JF1BD
NOMESCO Finland
Very extensive small bowel CT
10.1
8.5
16
16
M45
ICD-10 Finland
Ankylosing spondylitis
2.8
8.5
52
189
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.6
8.5
58
224
K56.0
ICD-10 Finland
Paralytic ileus
5.1
8.5
25
49
D04
ICPC
Rectal/anal pain
3.8
8.4
34
91
R01AD08
ATC
fluticasone; nasal
1.4
8.4
555
4349
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
8.4
824
6863
M25.5
ICD-10 Finland
Pain in joint
1.4
8.3
508
3930
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
+∞
8.3
8
*
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
8.6
8.3
17
20
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
8.3
770
6363
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
3.2
8.3
42
135
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
8.3
730
5988
SPAT1301
SPAT
No procedures
1.4
8.2
542
4252
R06AX27
ATC
desloratadine; oral
1.4
8.2
538
4215
K02.1
ICD-10 Finland
Caries of dentine
1.3
8.1
1190
10460
K62.4
ICD-10 Finland
Stenosis of anus and rectum
11.7
8.1
14
12
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
4.0
8.1
30
75
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.5
8.0
62
256
SPAT1255
SPAT
Intravenous administration of medicine
1.9
8.0
112
602
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
8.0
133
759
SPAT1254
SPAT
Administration of medicine
1.6
8.0
228
1514
AA1AD
NOMESCO Finland
CT of head and brain
1.4
7.9
343
2493
I84.5
ICD-10 Finland
External hemorrhoids without complication
2.5
7.9
59
241
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.8
7.9
144
845
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
13.1
7.9
13
10
WX110
NOMESCO Finland
Local anesthesy
1.3
7.9
1417
12780
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
7.9
187
1186
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
7.8
1178
10368
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
7.8
102
533
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.3
7.8
70
313
S29
ICPC
Skin symptom/complaint other
1.5
7.8
266
1840
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
45.1
7.7
9
*
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
45.1
7.7
9
*
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
7.4
7.7
17
23
WX892
NOMESCO Finland
Monitored bed care
1.8
7.6
122
687
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
18.4
7.6
11
6
K62.3
ICD-10 Finland
Rectal prolapse
4.2
7.6
27
65
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.2
7.5
22
43
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.3
7.5
68
305
L04AA29
ATC
tofacitinib; oral
10.1
7.5
14
14
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.4
7.5
62
266
K08.80
ICD-10 Finland
Toothache NOS
1.7
7.5
154
938
WZA90
NOMESCO Finland
Other doctors statement
1.4
7.5
435
3331
UJF02
NOMESCO Finland
Peroral enteroscopy
7.1
7.5
17
24
R01AD12
ATC
fluticasone furoate; nasal
1.3
7.4
594
4788
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
7.4
115
643
JHD30
NOMESCO Finland
Incomplete incision of fistula-in-ano
13.4
7.4
12
9
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.2
7.4
72
335
N06AX11
ATC
mirtazapine; oral
1.3
7.3
557
4454
M03BX02
ATC
tizanidine; oral
1.3
7.3
1227
10910
5589X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis, Other and unspecified non-infectious gastro-enteritis and colitis
+∞
7.3
7
*
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
+∞
7.3
7
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.0
7.3
40
137
K60.1
ICD-10 Finland
Chronic anal fissure
2.7
7.3
47
177
WX402
NOMESCO Finland
General anaesthesia
1.5
7.3
290
2073
SPAT1153
SPAT
Removal of sutures
1.3
7.2
502
3955
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
7.2
496
3904
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
7.2
185
1198
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
2.2
7.2
71
334
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.2
507
4006
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
7.1
1067
9337
Z71.8
ICD-10 Finland
Other specified counselling
1.4
7.1
440
3399
K62.6
ICD-10 Finland
Ulcer of anus and rectum
4.0
7.1
26
65
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
3.8
7.1
28
75
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.5
7.0
210
1411
J01FA09
ATC
clarithromycin; systemic
1.3
7.0
588
4768
R05
ICPC
Cough
1.4
7.0
379
2870
R02
ICPC
Shortness of breath/dyspnoea
1.6
7.0
185
1205
SPAT1131
SPAT
Colonoscopy
2.4
6.9
55
231
J01AA02
ATC
doxycycline; systemic
1.3
6.9
1500
13729
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
13.8
6.9
11
8
WVA20
NOMESCO Finland
Medicine administration
2.9
6.9
40
141
SXC05
NOMESCO Finland
Other oral or dental procedure
1.8
6.8
106
591
K60.2
ICD-10 Finland
Anal fissure, unspecified
3.0
6.8
36
121
J01DA01
ATC
[U] cefalexin; systemic
1.3
6.7
1224
10941
E0000UV
ATC
NA
1.3
6.7
720
6028
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.6
6.7
47
186
WX720
NOMESCO Finland
Own respiration
2.1
6.7
70
339
A02BC04
ATC
rabeprazole; oral
1.6
6.6
149
933
A01
ICPC
Pain general/multiple sites
1.8
6.6
117
683
K59.4
ICD-10 Finland
Anal spasm
7.8
6.6
14
18
JFB00
NOMESCO Finland
Partial resection of small intestine
3.4
6.6
29
85
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
6.6
111
637
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.5
6.5
47
190
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
6.5
507
4059
R10.2
ICD-10 Finland
Pelvic and perineal pain
2.5
6.5
47
191
M02AA07
ATC
piroxicam; topical
1.3
6.4
567
4617
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
6.4
724
6091
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.4
396
3058
JGB96
NOMESCO Finland
Other proctectomy or excision of rectum
70.0
6.4
7
*
L88
ICPC
Rheumatoid/seropositive arthritis
2.1
6.4
65
307
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.6
6.4
43
168
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
6.4
104
592
A06AD11
ATC
lactulose; oral
1.6
6.3
177
1173
M01AH02
ATC
rofecoxib; oral
1.5
6.3
181
1204
D07AD01
ATC
clobetasol; topical
1.4
6.3
256
1837
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
6.3
155
994
XQ800
NOMESCO Finland
Prick test
1.6
6.3
144
908
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
6.3
6
*
JFH31
NOMESCO Finland
Laparoscopic total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
+∞
6.3
6
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
6.2
560
4568
N06AB10
ATC
escitalopram; oral
1.4
6.2
382
2946
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
3.8
6.2
24
64
R74
ICPC
Upper respiratory infection acute
1.3
6.2
576
4726
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.7
6.1
40
152
SDA02
NOMESCO Finland
Parodonthologic therapy
1.3
6.1
608
5031
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
2.2
6.1
59
277
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.6
6.1
168
1109
A07AA02
ATC
nystatin; oral
1.9
6.0
88
482
N02AA05
ATC
oxycodone; systemic
1.5
6.0
187
1267
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
6.0
157
1022
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.0
309
2315

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1418
1709
17.86
307.65
2.0
1.2
—
—
—
0
0
185
24
83.16
307.65
2.7
2.4
114.13
251.98
au/ml
—
37
5
1817
7408
6.32
307.65
7.8
4.5
37.07
36.05
g/l
15.45
1740
6902
1852
2116
30.91
307.65
6.6
1.3
210.29
84.44
ug/g
24.16
1733
1610
1869
9823
4.58
255.34
11.1
5.5
0.04
0.04
e9/l
1.04
1718
8565
1435
6318
3.98
252.92
10.0
5.6
—
—
—
0
0
1859
9798
4.50
251.26
11.1
5.5
0.56
0.57
e9/l
1.34
1705
8550
1896
10173
4.58
248.89
11.3
5.8
0.19
0.19
e9/l
0.40
1756
9032
2313
14651
8.74
241.51
14.4
6.7
71.62
75.88
u/l
8.41
2263
13816
1870
10156
4.34
235.57
11.2
5.5
1.93
1.98
e9/l
0.62
1741
9035
1714
8882
3.96
228.66
11.5
5.7
0.73
0.67
%
6.12
1644
8329
1579
7759
3.81
228.39
3.4
2.1
75.28
74.64
nmol/l
0.44
1512
7094
1741
9186
3.95
224.33
11.3
5.6
2.91
2.84
%
0.63
1673
8591
1747
9253
3.95
223.45
11.7
5.9
8.51
8.39
%
0.94
1683
8713
1750
9460
3.83
212.69
10.9
5.4
56.09
56.69
%
1.49
1683
8905
1759
9591
3.81
209.75
11.5
5.6
29.25
28.77
%
1.23
1692
8999
1936
11287
4.17
207.46
12.9
8.7
3.89
4.06
e9/l
3.63
1773
9912
1066
4487
3.40
187.95
3.3
2.0
2.60
2.85
mg/l
3.16
964
3841
2150
14507
4.44
162.96
6.6
3.7
10.29
10.47
mm/h
0.27
2043
13528
86
35
25.41
122.53
1.9
1.3
10.01
8.64
mg/l
0.73
73
29
1181
6690
2.45
102.54
4.5
3.1
27.81
33.99
u/l
1.89
1091
6391
355
1110
3.56
94.21
1.4
1.2
—
—
—
0
0
422
1512
3.15
89.61
5.8
4.1
0.62
0.91
%
1.46
112
405
397
1375
3.24
89.23
5.4
3.9
0.33
0.63
%
1.93
81
300
406
1444
3.16
87.16
6.0
4.2
0.07
0.12
%
0.82
107
374
390
1364
3.20
86.07
5.9
4.2
0.03
0.62
%
0.93
86
320
546
2315
2.74
84.89
2.6
2.5
23.74
24.24
%
0.33
469
1993
610
2754
2.61
83.46
2.6
2.4
14.24
14.06
umol/l
0.21
577
2557
1432
9358
2.24
82.75
3.9
2.7
97.92
109.73
ug/l
1.30
1359
8758
572
2516
2.65
82.43
2.5
2.4
2.40
2.37
g/l
0.80
536
2338
1368
8817
2.22
81.28
13.7
8.5
0.00
0.00
e9/l
1.31
1196
7233
870
4715
2.30
78.64
7.9
4.1
—
—
—
0
0
1008
5811
2.23
78.35
3.9
2.4
57.08
56.64
u/l
0.13
955
5399
2424
20626
6.76
77.18
22.9
11.7
16.80
22.36
mg/l
19.27
2084
15972
604
2817
2.51
76.42
1.6
1.6
—
—
—
0
0
1439
9625
2.17
75.75
6.4
5.9
10.65
11.11
umol/l
0.72
1385
9126
1237
7933
2.11
71.12
2.4
2.0
—
—
—
0
0
195
523
3.96
64.08
1.4
1.2
88.82
93.08
titre
0.07
17
52
149
346
4.52
59.22
4.8
3.6
54.95
56.88
%
0.94
149
346
146
335
4.57
58.90
4.4
3.2
3.65
4.12
e9/l
2.10
146
335
721
4194
2.01
50.03
1.7
1.7
—
—
—
0
0
202
656
3.26
49.48
1.7
1.8
—
—
—
0
0
804
4875
1.96
49.38
8.9
6.4
—
—
—
0
0
1745
13621
1.93
48.09
4.9
3.9
—
—
—
0
0
2425
21837
4.68
45.31
23.7
13.2
74.91
74.81
umol/l
0.07
2425
21827
525
2824
2.09
44.51
1.5
1.3
501.72
494.10
titre
0.04
116
559
2425
21966
4.47
42.12
18.7
8.9
25.95
27.11
u/l
2.45
2403
21306
1214
8713
1.76
41.31
6.9
6.4
1.22
1.21
mmol/l
1.69
1032
7371
688
4183
1.89
40.47
1.6
1.4
2.34
2.33
g/l
0.05
449
2668
1027
7070
1.77
40.01
2.0
1.9
97.29
96.27
pmol/l
0.28
567
3827
267
1138
2.51
39.17
1.9
1.8
1.23
1.39
g/l
0.80
249
1051
318
1478
2.32
38.45
2.3
2.7
10.97
10.44
g/l
1.73
299
1354
300
1393
2.31
36.26
3.1
2.7
4.14
4.11
e9/l
0.06
236
1153
161
563
2.99
34.61
1.3
1.1
—
—
—
0
0
326
1603
2.19
34.21
3.0
2.2
0.24
0.22
g/l
5.90
305
1497
505
2912
1.92
34.19
2.0
1.7
1066.48
1188.24
nmol/l
2.27
356
2266
707
4542
1.78
33.72
4.5
4.2
—
—
—
0
0
2291
20532
2.39
32.67
18.4
13.0
139.57
139.64
mmol/l
0.81
2243
19996
2045
17623
1.88
32.04
24.8
14.3
13.53
13.53
%
0.08
2029
17244
2294
20607
2.37
31.89
18.4
13.1
3.92
3.95
mmol/l
8.15
2244
20031
1078
7861
1.65
31.73
5.9
5.8
1.22
1.21
mmol/l
1.71
997
7157
130
429
3.14
30.87
1.2
1.2
237.23
257.90
u/ml
0.36
82
270
967
6906
1.65
30.57
7.7
7.8
1.12
1.19
inr
2.63
295
2093
724
4824
1.70
29.65
1.3
1.3
1.98
1.62
u/ml
0.18
166
1345
104
310
3.46
29.11
1.1
1.2
—
—
—
0
0
758
5213
1.65
27.05
1.9
2.0
—
—
—
0
0
1391
11065
1.58
26.83
5.0
4.5
6.49
6.58
mmol/l
0.94
1289
10217
1571
12856
1.60
26.83
4.9
3.9
2696.59
1452.62
e6/l
0.19
22
172
744
5112
1.65
26.55
4.1
3.9
7.40
7.40
ph
0.38
129
1010
573
3709
1.71
25.53
2.1
1.6
91892305.54
37370667.34
pmol/l
0.76
518
3179
2363
21815
2.52
25.47
18.5
11.1
—
—
—
0
0
178
767
2.42
25.28
1.2
1.2
—
—
—
0
0
1251
9802
1.55
25.11
3.9
3.3
0.00
0.00
estimate
0.80
287
1791
1239
9704
1.55
24.80
3.9
3.2
0.00
0.00
estimate
1.08
282
1819
370
2130
1.87
24.50
3.1
2.7
5.63
7.53
umol/l
1.99
328
1846
61
142
4.38
24.17
1.2
1.2
171.67
144.62
titre
0.13
18
26
420
2528
1.79
24.03
1.2
1.2
—
—
—
0
0
96
316
3.12
22.92
1.8
1.6
0.66
0.86
g/l
1.25
73
242
686
4776
1.60
22.53
4.5
3.7
93.85
92.88
%
0.46
668
4663
1225
9698
1.52
22.48
5.2
4.4
0.00
0.00
estimate
0.50
286
1870
986
7474
1.53
22.10
3.5
3.1
—
5.67
—
0
6
81
246
3.37
22.06
4.1
3.4
0.83
1.46
%
1.45
58
214
164
762
2.23
19.54
1.4
1.5
6.57
8.74
u/ml
—
10
16
2456
23428
3.75
19.18
31.7
17.3
6.74
6.72
e9/l
0.17
2435
22863
305
1778
1.81
19.16
2.8
2.3
38.71
65.31
u/l
0.49
266
1520
2455
23416
3.69
19.11
31.5
17.2
90.96
90.43
fl
7.37
2447
23141
2455
23419
3.68
19.04
31.4
17.2
30.28
30.21
pg
1.44
2447
23141
2455
23422
3.68
18.98
31.6
17.3
4.50
4.56
e12/l
7.02
2435
22858
2453
23398
3.57
18.84
31.7
17.3
266.38
254.51
e9/l
15.33
2435
22880
2455
23431
3.65
18.78
31.8
17.4
135.74
136.98
g/l
4.79
2446
23153
122
508
2.47
18.67
3.0
3.0
—
—
—
0
0
691
5037
1.51
17.75
3.0
2.6
—
—
—
0
0
562
3922
1.56
17.62
1.5
1.5
20.45
20.38
nmol/l
0.04
508
3433
309
1883
1.73
16.57
1.5
1.5
—
—
—
0
0
286
1708
1.76
16.46
1.1
1.2
—
—
—
0
0
52
145
3.64
16.18
4.1
3.3
54.78
54.58
%
0.02
32
109
302
1882
1.69
14.86
2.2
2.1
332.44
375.61
nmol/l
3.87
279
1742
727
5533
1.44
14.47
3.5
2.9
—
—
—
0
0
283
1773
1.67
13.61
2.7
2.7
1.73
1.76
%
0.22
256
1593
470
3324
1.51
13.46
3.4
3.4
602.39
467.20
ng/l
0.22
298
2306
719
5544
1.42
13.06
3.4
3.0
43.41
81.84
e6/l
1.23
585
4214
72
278
2.64
12.95
1.1
1.1
1.49
1.48
g/l
0.08
66
248
163
881
1.91
12.93
1.1
1.1
—
—
—
0
0
109
510
2.19
12.82
1.2
1.3
—
—
—
0
0
115
550
2.14
12.80
3.4
3.5
58.12
2675.22
u/ml
0.81
99
466
567
4203
1.45
12.74
3.9
3.6
1.02
1.02
kg/l
0.48
86
577
1127
9402
1.36
12.56
4.9
3.9
—
—
—
0
0
252
1567
1.68
12.44
3.1
4.2
18.43
24.13
ug/l
0.18
177
1251
475
3423
1.48
12.30
1.3
1.3
2.54
11.50
u/ml
10.36
162
1421
835
6660
1.38
12.27
4.0
3.4
81.57
82.03
e6/l
0.01
623
4554
96
448
2.19
11.39
1.3
1.5
—
—
—
0
0
666
5168
1.39
11.39
4.3
3.6
0.00
0.00
estimate
1.28
288
1813
264
1703
1.62
11.26
4.3
3.5
—
—
—
0
0
1999
18409
1.43
11.18
26.1
14.8
332.37
333.24
g/l
4.46
1993
18272
489
3618
1.44
10.91
1.3
1.3
16.37
28.51
iu/ml
4.85
152
1127
648
5036
1.39
10.90
3.3
2.9
0.32
0.40
e6/l
0.42
513
3745
313
2119
1.55
10.84
8.7
7.2
104.43
104.44
mmol/l
0.02
307
2072
2120
19769
1.48
10.82
22.1
12.5
39.75
40.43
%
3.01
1604
15428
1636
14616
1.35
10.81
3.7
3.0
44.23
43.34
u/l
0.17
1567
13875
107
533
2.05
10.75
4.8
5.8
1.28
1.23
mmol/l
0.18
100
463
17
26
6.58
10.63
2.1
2.1
—
—
—
0
0
640
4987
1.38
10.54
3.3
2.8
—
—
—
0
0
477
3547
1.43
10.30
2.8
2.7
553.99
554.93
mosm/kgh2o
0.03
408
2996
28
71
3.98
10.04
1.5
1.7
—
—
—
0
0
370
2640
1.47
9.92
2.0
2.0
—
—
—
0
0
579
4483
1.38
9.82
1.8
1.7
1.03
0.99
mg/l
0.10
451
3320
87
415
2.14
9.82
1.4
1.5
109.49
116.63
u/ml
0.23
21
86
204
1280
1.65
9.72
2.8
2.8
70.65
71.61
e9/l
0.13
156
961
502
3802
1.40
9.71
2.7
2.5
4.86
6.24
e6/l
1.94
447
3324
324
2269
1.49
9.53
1.8
1.7
—
—
—
0
0
813
6662
1.33
9.44
3.4
3.1
66.68
52.64
ng/l
0.25
464
4017
330
2331
1.48
9.29
1.5
1.4
—
—
—
0
0
230
1517
1.57
8.92
4.1
3.8
2.04
1.97
mmol/l
0.08
180
1219
39
135
2.92
8.71
1.1
1.1
—
—
—
0
0
45
169
2.69
8.65
4.8
3.7
—
—
—
0
0
112
621
1.84
8.29
1.1
1.1
1.13
3.66
u/ml
—
9
90
122
696
1.79
8.23
1.6
1.9
1.60
1.48
g/l
0.64
105
607
90
469
1.95
8.05
1.6
1.4
280.04
302.04
ug/g
0.39
53
265
227
1530
1.53
7.99
4.3
3.7
5.94
5.86
kpa
0.66
215
1483
283
1998
1.47
7.96
23.8
20.4
1.23
1.25
inr
0.10
55
294
32
105
3.07
7.86
1.1
1.1
1374.63
1538.42
miu/ml
0.32
32
105
36
127
2.86
7.80
1.1
1.0
—
—
—
0
0
136
814
1.71
7.78
3.6
4.0
24.33
24.15
mmol/l
0.24
124
744
730
6025
1.30
7.73
3.2
3.2
2.35
2.35
mmol/l
0.28
638
5378
49
209
2.37
7.30
1.4
1.4
—
—
—
0
0
312
2282
1.42
7.25
5.6
6.0
1.03
1.04
mmol/l
0.17
295
2124
738
6146
1.28
7.20
2.7
2.2
—
—
—
0
0
378
2862
1.38
7.17
4.3
3.5
0.80
0.82
mmol/l
2.83
342
2701
187
1238
1.55
7.15
2.9
2.7
225.13
166.12
ng/l
0.65
165
1115
11
16
6.90
7.15
1.1
1.0
—
—
—
0
0
380
2882
1.38
7.13
3.1
2.7
2.80
2.53
e6/l
0.23
226
1539
546
4373
1.32
7.13
3.7
3.3
—
—
—
0
0
13
23
5.68
7.06
1.8
1.5
—
—
—
0
0
48
206
2.36
7.06
1.4
1.3
7.04
6.73
g/l
0.24
34
146
48
206
2.36
7.06
1.4
1.3
2.98
3.02
g/l
0.07
34
147
48
206
2.36
7.06
1.4
1.3
0.33
0.38
g/l
0.73
33
145
397
3039
1.36
7.03
2.9
2.5
0.81
1.10
e6/l
0.92
242
1685
35
130
2.72
6.93
1.7
1.6
—
—
—
0
0
134
830
1.65
6.77
1.3
1.3
0.24
0.98
u/ml
—
8
76
191
1287
1.52
6.75
1.4
1.4
—
—
—
0
0
184
1231
1.53
6.72
4.0
4.0
84.37
85.63
ng/l
0.07
169
1107
2003
18865
1.31
6.63
4.9
4.6
1.67
1.97
mu/l
2.99
1898
17604
156
1032
1.55
6.02
5.8
7.2
24.42
24.54
mmol/l
0.16
150
959
52
248
2.12
6.00
2.9
2.7
6.66
123.14
u/ml
0.96
52
227
181
1254
1.48
5.63
3.7
2.9
4.40
4.72
kpa
1.39
169
1212
1710
15926
1.23
5.47
4.1
3.9
14.62
14.56
pmol/l
0.47
1604
14746
201
1432
1.44
5.41
1.3
1.3
195.07
201.99
u/ml
0.04
187
1321
89
528
1.71
5.35
2.7
3.8
1.30
1.45
mg/l
1.58
81
494
230
1684
1.40
5.32
4.3
3.9
—
—
—
0
0
101
621
1.65
5.32
1.7
1.6
1.21
1.18
g/l
0.43
94
585
557
4628
1.26
5.30
2.7
2.2
—
—
—
0
0
66
362
1.85
5.18
1.0
1.1
—
—
—
0
0
213
1557
1.40
4.99
7.8
8.9
123.92
123.38
g/l
0.15
207
1500
133
888
1.53
4.97
9.9
10.9
—
—
—
0
0
173
1220
1.45
4.94
3.3
2.4
—
—
—
0
0
627
5323
1.24
4.89
2.2
2.1
288.00
201.12
u/l
0.33
601
5043
36
162
2.24
4.85
2.0
2.4
55.60
44.60
%
—
5
25
127
846
1.53
4.81
2.7
2.3
—
—
—
0
0
27
107
2.54
4.79
2.9
3.4
—
—
—
0
0
114
743
1.56
4.76
1.3
1.2
—
—
—
0
0
192
1394
1.41
4.68
8.7
9.2
—
—
—
0
0
88
543
1.64
4.62
1.3
2.1
10.63
10.47
g/l
0.08
72
468
95
598
1.61
4.60
1.8
1.7
0.23
0.23
g/l
0.28
88
564
93
584
1.62
4.55
2.6
2.5
—
—
—
0
0
247
1893
1.34
4.32
7.4
8.0
1.14
1.04
mmol/l
0.15
197
1473
167
1204
1.41
4.26
2.2
2.2
3884.68
6060.40
u/l
0.41
65
500
19
67
2.85
4.22
3.5
3.0
—
—
—
0
0
247
1900
1.33
4.22
7.4
8.0
5.08
5.12
kpa
0.22
239
1816
151
1071
1.44
4.22
4.4
4.9
—
—
—
0
0
247
1901
1.33
4.21
7.3
8.0
12.64
12.65
kpa
0.01
239
1818
28
122
2.31
4.10
1.1
1.5
4.73
8.35
ug/l
1.49
22
103
84
529
1.61
4.10
1.3
1.2
23.78
6.27
u/ml
—
10
87
63
370
1.72
4.01
1.0
1.1
—
—
—
0
0
76
473
1.63
3.91
2.5
3.7
7.42
7.42
ph
0.01
60
399
21
82
2.57
3.88
3.1
2.4
—
—
—
0
0
199
1502
1.35
3.87
7.4
7.5
1.34
1.37
mmol/l
0.15
192
1436
32
154
2.09
3.73
3.2
3.3
—
—
—
0
0
81
520
1.58
3.68
1.3
1.2
3.97
2.42
u/ml
—
9
52
205
1569
1.33
3.65
1.4
1.4
—
—
—
0
0
32
156
2.06
3.61
1.3
1.1
—
—
—
0
0
60
362
1.67
3.51
2.6
2.8
—
—
—
0
0
113
790
1.45
3.46
1.7
1.7
—
—
—
0
0
571
4954
1.20
3.45
3.6
3.4
—
—
—
0
0
67
420
1.61
3.39
2.1
3.0
23.26
24.75
mmol/l
2.18
56
372
498
4281
1.20
3.32
3.0
2.9
1695.35
1161.61
ng/l
1.03
421
3561
1443
13515
1.16
3.30
3.6
3.3
—
—
—
0
0
196
1514
1.32
3.30
7.7
8.1
8.70
8.77
mmol/l
0.05
186
1455
44
249
1.78
3.24
1.9
1.4
63.44
67.71
mmol/l
0.23
27
211
18
72
2.51
3.21
2.7
2.6
—
—
—
0
0
330
2734
1.24
3.17
2.6
2.1
29.37
29.68
s
0.44
319
2646
35
186
1.89
3.15
2.4
2.7
1.18
1.13
e9/l
0.09
18
108
94
649
1.47
3.10
1.6
1.3
—
—
—
0
0
72
471
1.54
3.07
1.3
2.1
38.02
38.15
g/l
0.06
63
411
6
197
0.30
3.07
6.0
18.4
1395.17
1461.31
nmol/l
—
6
192
68
440
1.56
3.05
1.3
1.2
15.46
44.12
u/ml
—
5
42
25
119
2.11
3.04
1.4
1.5
5.75
6.34
u/l
0.28
20
98
115
829
1.41
3.02
3.3
3.1
—
—
—
0
0
58
363
1.61
2.99
1.8
2.4
16.54
16.55
%
0.01
28
176
6
195
0.31
2.93
5.5
13.5
942.17
810.99
nmol/l
—
6
187
63
405
1.57
2.92
2.6
3.8
2.57
2.39
mmol/l
0.23
38
256
41
237
1.74
2.85
1.4
1.3
—
—
—
0
0
51
315
1.63
2.79
2.3
1.7
—
—
—
0
0
57
362
1.59
2.79
3.1
2.2
7.28
5.52
umol/l
0.51
43
262
632
5626
1.17
2.76
4.8
4.5
3.37
2.19
ug/l
0.40
566
5078
29
152
1.92
2.75
2.5
2.8
993.77
755.28
e6/l
0.96
13
64
559
4939
1.17
2.68
3.3
3.3
643.09
308.26
mg/l
0.66
365
3211
62
406
1.54
2.68
1.7
1.7
7323.96
13104.33
e6/l
1.41
47
305
28
147
1.92
2.65
1.3
1.2
—
80.47
—
0
9
67
448
1.51
2.63
2.7
3.5
40.00
64.18
mg/l
0.92
61
362
67
449
1.51
2.61
2.7
3.5
39.77
40.10
mg/l
0.01
61
362
8
20
4.01
2.56
1.1
1.1
—
—
—
0
0
27
143
1.90
2.51
1.8
2.3
13.14
13.58
%
0.07
14
71
30
165
1.83
2.49
1.2
1.1
367.58
399.87
nmol/l
0.34
24
153
34
195
1.75
2.47
1.6
1.6
52.70
55.71
%
0.15
20
127
628
5631
1.15
2.47
3.2
3.3
7.75
8.02
mmol/l
0.73
548
4822
580
5175
1.16
2.43
4.0
4.1
10.34
9.61
mg/mmol
0.12
380
3379
165
1303
1.29
2.42
2.2
2.6
67.22
66.89
g/l
0.20
154
1201
181
1448
1.27
2.40
3.4
3.2
—
—
—
0
0
357
3071
1.19
2.36
2.7
2.8
2.44
2.43
mmol/l
0.23
292
2694
1888
18212
1.15
2.36
5.4
5.0
38.62
38.89
mmol/mol
0.54
1783
17132
51
330
1.56
2.36
3.2
3.7
—
—
—
0
0
178
1425
1.27
2.35
3.1
3.5
1.23
1.23
mmol/l
0.26
166
1237
136
1052
1.31
2.34
2.0
2.3
—
—
—
0
0
13
53
2.46
2.27
2.8
1.9
32.91
51.41
ug/l
1.91
13
53
162
1288
1.28
2.27
1.4
1.4
25.48
24.66
iu/l
0.11
140
1097
29
163
1.79
2.27
1.2
1.3
4210.07
78695.90
e6/l
1.11
15
114
64
439
1.47
2.27
2.7
3.5
3.14
2.80
ratio
0.06
11
42
89
649
1.39
2.26
1.8
2.1
21.11
1.68
ug/l
0.58
75
581
17
79
2.16
2.24
1.8
3.0
92.90
113.81
umol/l
—
10
42
56
375
1.50
2.23
1.7
2.4
134.50
132.05
g/l
0.30
42
275
20
100
2.01
2.20
2.1
2.8
600.35
958.27
u/ml
0.62
20
100
291
2475
1.20
2.19
1.3
1.2
—
—
—
0
0
18
87
2.08
2.17
1.1
1.1
—
—
—
0
0
51
338
1.52
2.14
1.4
1.3
2.74
5.13
u/ml
1.39
23
154
51
339
1.51
2.12
2.0
1.8
—
—
—
0
0
13
55
2.37
2.12
1.0
1.0
—
—
—
0
0
19
95
2.01
2.10
1.3
1.1
27.56
35.42
mmol/l
1.48
13
89
168
1356
1.26
2.10
2.1
2.2
4.47
7.63
ug/l
3.76
142
1221
5
10
5.01
2.07
2.2
2.1
—
—
—
0
0
137
1082
1.28
2.05
2.6
3.4
5.01
5.15
kpa
1.57
125
1018
551
4956
1.14
2.05
2.6
2.5
6115.28
4116.37
umol/l
0.45
490
4389
202
1675
1.22
1.99
2.4
2.2
12.15
12.78
nmol/l
0.48
182
1497
16
77
2.08
1.96
1.2
1.1
—
—
—
0
0
27
156
1.74
1.96
1.4
1.4
27.80
34.63
%
0.29
12
102
100
766
1.32
1.90
2.1
2.0
21.99
21.25
s
0.23
87
662
686
6294
1.12
1.85
1.6
1.6
—
—
—
0
0
130
1619
0.79
1.84
1.4
1.4
—
—
—
0
0
5
12
4.17
1.82
2.2
1.9
—
—
—
0
0
50
344
1.46
1.80
1.0
1.0
0.99
2.15
u/ml
2.81
18
170
23
131
1.76
1.77
1.3
1.2
—
—
—
0
0
565
5139
1.13
1.76
1.6
1.6
1.40
1.39
mmol/l
0.09
498
4407
51
356
1.44
1.72
1.2
1.2
—
—
—
0
0
45
307
1.47
1.71
1.4
1.3
—
—
—
0
0
108
851
1.28
1.70
1.9
1.7
—
—
—
0
0
12
55
2.19
1.67
2.1
2.5
370.00
139.00
e6/l
—
7
30
84
642
1.32
1.66
4.6
4.9
—
—
—
0
0
16
83
1.93
1.64
1.6
1.7
—
—
—
0
0
22
127
1.74
1.64
1.1
1.2
—
—
—
0
0
44
302
1.47
1.63
1.4
1.6
—
—
—
0
0
5
14
3.58
1.61
1.4
1.2
—
—
—
0
0
15
77
1.95
1.59
3.5
3.1
7.40
7.43
ph
—
8
22
242
2789
0.85
1.57
1.3
1.3
—
—
—
0
0
29
183
1.59
1.57
1.0
1.1
—
—
—
0
0
1996
19483
1.12
1.53
4.2
4.0
5.79
5.82
mmol/l
0.44
1872
18070
22
130
1.70
1.53
2.0
3.0
36.71
41.63
%
—
10
40
131
1073
1.23
1.51
2.7
3.4
7.42
7.41
ph
0.82
19
135
32
210
1.53
1.48
1.3
1.4
8.40
12.97
mmol/l
—
7
43
35
235
1.50
1.47
2.6
2.3
—
—
—
0
0
52
377
1.39
1.46
2.5
3.6
—
—
—
0
0
75
576
1.31
1.46
1.1
1.1
—
—
—
0
0
12
59
2.04
1.43
1.7
1.7
—
—
—
0
0
159
1338
1.20
1.42
3.6
3.4
4.51
4.56
pmol/l
0.37
146
1195
68
519
1.32
1.40
1.9
1.9
212.82
202.85
pmol/l
0.29
68
488
22
135
1.64
1.35
1.0
1.1
15.24
10.89
iu/ml
—
5
39
25
159
1.58
1.34
1.5
2.2
—
—
—
0
0
20
121
1.66
1.30
5.3
7.2
—
—
—
0
0
293
2619
1.13
1.23
1.9
1.8
—
—
—
0
0
55
416
1.33
1.23
2.3
1.9
—
—
—
0
0
312
2801
1.13
1.23
1.5
1.4
—
—
—
0
0
10
49
2.04
1.22
1.1
1.0
—
—
—
0
0
61
470
1.31
1.21
1.1
1.3
—
—
—
0
0
41
297
1.39
1.20
2.6
2.4
—
—
—
0
0
22
140
1.58
1.20
1.9
2.2
9.65
11.36
%
0.93
22
140
6
26
2.31
1.18
5.5
6.5
—
—
—
0
0
16
95
1.69
1.13
1.0
1.0
223.36
294.48
ng/l
0.95
11
56
16
95
1.69
1.13
1.0
1.0
732.60
680.96
ng/l
—
10
56
107
891
1.21
1.11
1.3
1.3
211.13
225.92
miu/ml
0.14
45
436
65
514
1.27
1.08
1.1
1.1
—
—
—
0
0
28
194
1.45
1.06
1.4
1.6
277.14
281.93
mosm/kgh2o
0.30
21
149
22
145
1.52
1.06
1.2
1.1
1.06
1.05
ratio
—
8
54
34
245
1.39
1.05
1.2
1.3
—
0.38
nmol/l
—
0
15
29
203
1.43
1.05
3.7
4.9
65.61
85.60
u/ml
—
7
60
12
67
1.79
1.04
1.3
1.3
—
—
—
0
0
26
180
1.45
1.00
1.4
1.3
70.97
229.14
pmol/l
0.48
11
57
15
91
1.65
1.00
1.5
1.6
—
—
—
0
0
9
48
1.88
1.00
1.0
1.3
—
—
—
0
0
13
76
1.71
0.99
1.1
1.0
—
—
—
0
0
50
390
1.29
0.95
4.1
4.0
—
—
—
0
0
13
77
1.69
0.95
5.4
5.2
—
—
—
0
0
781
8205
0.93
0.95
2.5
2.5
—
—
—
0
0
78
642
1.22
0.94
3.6
3.3
0.38
0.27
g/l
0.50
36
267
39
294
1.33
0.94
2.3
2.8
—
—
—
0
0
30
217
1.39
0.93
1.2
1.3
—
—
nmol/l
—
0
0
25
175
1.43
0.93
3.0
2.4
—
—
—
0
0
13
78
1.67
0.91
1.4
1.2
—
—
—
0
0
35
262
1.34
0.89
1.3
1.6
—
—
—
0
0
28
202
1.39
0.89
2.8
2.6
—
—
—
0
0
338
3111
1.10
0.89
1.7
1.7
—
—
—
0
0
238
2153
1.12
0.87
1.6
1.4
—
—
—
0
0
14
87
1.61
0.87
1.3
1.1
—
—
—
0
0
8
44
1.82
0.85
1.6
2.7
—
—
—
0
0
22
153
1.44
0.85
1.2
1.1
—
—
—
0
0
18
120
1.50
0.85
1.3
1.2
—
—
—
0
0
16
104
1.54
0.84
45.1
34.8
6.97
7.58
ug/l
0.74
16
96
32
239
1.34
0.84
1.4
1.5
—
—
—
0
0
13
81
1.61
0.81
1.3
1.3
—
—
—
0
0
44
347
1.27
0.80
1.1
1.2
—
—
—
0
0
30
224
1.34
0.80
1.7
1.6
—
—
—
0
0
30
224
1.34
0.80
1.7
1.6
—
—
—
0
0
30
224
1.34
0.80
1.7
1.6
—
—
—
0
0
30
224
1.34
0.80
1.3
1.3
—
—
—
0
0
30
224
1.34
0.80
1.7
1.6
—
—
—
0
0
50
401
1.25
0.79
5.0
3.5
20.78
25.38
mg/l
0.75
34
253
6
33
1.82
0.79
1.7
2.1
—
—
—
0
0
0
25
0.00
0.79
0.0
1.3
—
742.29
—
0
7
36
277
1.30
0.79
1.3
1.2
—
—
—
0
0
8
48
1.67
0.78
1.3
1.1
—
—
—
0
0
47
375
1.26
0.78
1.3
1.2
—
—
—
0
0
0
26
0.00
0.78
0.0
1.0
—
—
—
0
0
0
26
0.00
0.78
0.0
8.1
—
—
—
0
0
6
34
1.77
0.76
1.5
1.1
—
—
—
0
0
5
24
2.09
0.74
2.6
2.7
0.40
0.83
u/field
—
5
24
9
55
1.64
0.73
3.0
2.4
—
—
—
0
0
21
150
1.40
0.73
1.3
1.3
—
—
—
0
0
2064
20367
1.08
0.73
4.1
4.0
4.68
4.72
mmol/l
1.21
1972
19215
91
784
1.17
0.72
2.7
3.5
—
—
—
0
0
22
159
1.39
0.72
1.0
1.0
—
—
—
0
0
5
26
1.92
0.70
1.0
1.1
—
—
—
0
0
5
26
1.92
0.70
2.2
3.2
—
—
—
0
0
23
169
1.36
0.69
1.1
1.2
—
—
—
0
0
13
85
1.53
0.69
1.2
1.1
—
0.04
g/l
—
0
5
19
136
1.40
0.66
1.1
1.1
—
—
—
0
0
21
154
1.37
0.65
1.5
1.4
—
—
—
0
0
15
103
1.46
0.65
1.7
1.7
2.00
5.10
u/field
—
10
81
34
269
1.27
0.64
1.3
1.4
—
—
—
0
0
13
189
0.69
0.63
1.5
1.2
—
—
—
0
0
30
234
1.29
0.63
2.1
2.4
—
—
—
0
0
11
71
1.55
0.62
1.5
2.3
—
—
—
0
0
5
30
1.67
0.61
2.6
3.0
—
—
—
0
0
18
130
1.39
0.61
1.9
2.2
1.82
1.93
u/field
0.05
11
69
51
428
1.20
0.58
1.0
1.1
—
—
—
0
0
13
89
1.46
0.58
1.4
1.8
—
—
—
0
0
20
149
1.35
0.57
1.2
1.1
—
—
—
0
0
89
784
1.14
0.56
1.3
1.4
8.01
9.02
u/l
0.44
71
649
8
55
1.46
0.56
1.5
1.1
—
—
—
0
0
20
151
1.33
0.54
1.0
1.0
—
—
—
0
0
2084
20625
1.06
0.53
4.5
4.3
2.76
2.83
mmol/l
1.80
1971
19312
17
125
1.36
0.53
1.5
1.5
1482.00
2092.91
ml
—
5
23
46
386
1.20
0.53
1.2
1.4
24.14
22.78
u/l
0.10
39
322
11
75
1.47
0.50
1.1
1.1
—
—
—
0
0
6
41
1.46
0.50
2.2
1.3
2.20
3.06
mmol/l
—
6
35
65
743
0.87
0.49
1.4
1.4
—
—
—
0
0
7
46
1.52
0.48
1.0
1.1
—
—
—
0
0
50
428
1.17
0.48
1.0
1.1
—
—
—
0
0
29
235
1.24
0.48
3.6
3.0
0.80
0.84
nmol/l
0.17
23
182
97
871
1.12
0.48
11.5
10.8
24.19
24.30
mmol/l
0.11
86
825
14
102
1.37
0.47
1.4
1.2
—
—
—
0
0
21
165
1.28
0.45
1.1
1.1
—
—
—
0
0
66
746
0.88
0.44
1.4
1.4
—
—
—
0
0
143
1318
1.09
0.44
1.3
1.2
—
—
—
0
0
17
219
0.77
0.43
1.1
1.4
—
—
—
0
0
11
78
1.41
0.43
1.5
1.7
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
11.58
—
0
17
2044
20260
1.05
0.40
4.0
3.9
1.46
1.45
mmol/l
0.83
1947
19018
38
324
1.18
0.40
1.3
1.4
7.06
7.15
mmol/l
0.06
25
236
92
837
1.10
0.38
1.8
3.2
—
—
—
0
0
42
363
1.16
0.38
1.2
1.5
—
—
—
0
0
5
37
1.35
0.37
1.0
1.1
—
—
—
0
0
19
152
1.25
0.37
1.0
1.0
12.72
2.62
u/ml
—
7
43
8
116
0.69
0.37
1.0
1.4
—
—
—
0
0
69
766
0.90
0.36
1.5
1.5
—
—
—
0
0
103
946
1.09
0.36
1.6
2.2
—
—
—
0
0
109
1005
1.09
0.35
1.1
1.1
—
—
—
0
0
38
329
1.16
0.35
1.3
1.5
—
—
—
0
0
6
43
1.40
0.35
1.2
2.4
—
—
—
0
0
112
1037
1.08
0.34
10.8
10.5
0.61
0.68
%
1.21
112
1031
75
682
1.10
0.33
2.9
3.6
24.88
24.79
mmol/l
0.10
70
633
11
144
0.76
0.33
1.4
1.4
4296.00
76812.27
e6/l
—
5
88
6
86
0.70
0.33
3.7
3.0
—
—
—
0
0
6
86
0.70
0.33
7.3
5.9
—
—
—
0
0
23
192
1.20
0.32
1.1
1.4
—
—
—
0
0
11
84
1.31
0.30
4.4
3.2
—
—
—
0
0
7
55
1.27
0.30
25.4
14.3
—
—
—
0
0
7
55
1.27
0.30
1.4
1.1
—
—
—
0
0
39
440
0.88
0.29
1.4
1.3
—
—
—
0
0
116
1085
1.07
0.29
1.7
1.7
285.46
294.41
mu/l
0.13
107
981
24
205
1.17
0.27
1.1
1.1
—
—
—
0
0
14
113
1.24
0.26
1.1
1.5
—
—
—
0
0
5
74
0.68
0.26
1.6
1.8
—
—
—
0
0
20
169
1.18
0.25
1.2
1.1
—
—
—
0
0
13
105
1.24
0.24
1.2
1.1
278.80
193.06
iu/ml
0.28
13
105
5
38
1.32
0.23
1.0
1.2
—
—
—
0
0
5
38
1.32
0.23
1.0
1.2
—
—
—
0
0
5
38
1.32
0.23
1.0
1.2
—
—
—
0
0
110
1038
1.06
0.23
11.1
10.4
1.25
1.36
%
0.59
110
1033
16
134
1.20
0.23
2.2
2.6
725.33
622.17
ml
—
9
89
21
181
1.16
0.22
1.6
1.2
0.32
0.56
u/ml
—
8
78
12
146
0.82
0.22
1.5
1.5
—
—
—
0
0
342
3324
1.03
0.21
2.8
2.8
0.66
0.72
ug/l
0.63
223
2040
28
248
1.13
0.21
1.4
1.6
7.27
7.49
mmol/l
0.16
16
155
5
42
1.19
0.21
1.2
1.1
—
—
—
0
0
5
42
1.19
0.21
1.2
1.1
—
—
—
0
0
5
42
1.19
0.21
1.2
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.13
—
0
5
23
201
1.15
0.21
2.5
2.2
32.57
32.19
pg
0.11
23
201
12
98
1.23
0.21
2.0
2.2
28.27
99.18
ug/l
0.43
12
88
0
13
0.00
0.21
0.0
8.5
—
233.87
—
0
8
16
136
1.18
0.20
1.4
1.7
3.80
3.63
mg/l
0.06
16
130
12
144
0.83
0.19
1.5
1.4
—
—
—
0
0
6
51
1.18
0.19
2.5
1.6
—
—
—
0
0
154
1480
1.04
0.18
2.2
2.3
34.93
21.38
au/ml
0.47
12
101
17
147
1.16
0.18
1.1
1.3
—
—
—
0
0
124
1187
1.05
0.17
1.6
2.1
—
—
—
0
0
11
131
0.84
0.17
1.5
1.5
—
—
—
0
0
126
1209
1.04
0.16
1.6
2.2
—
—
—
0
0
40
369
1.09
0.16
1.1
1.1
8.64
5.16
u/ml
0.26
14
143
1961
19520
1.02
0.16
3.7
3.6
1.28
1.29
mmol/l
0.12
1854
18265
212
2183
0.97
0.16
4.0
4.0
32.16
31.55
%
0.36
153
1548
46
428
1.08
0.16
1.5
2.2
0.79
0.86
nmol/l
0.30
39
365
125
1202
1.04
0.15
1.6
2.2
—
—
—
0
0
10
83
1.21
0.15
3.6
2.7
—
—
—
0
0
126
1214
1.04
0.14
1.6
2.2
—
—
—
0
0
20
223
0.90
0.14
1.1
1.5
—
—
—
0
0
21
233
0.90
0.14
7.7
6.4
10.84
11.14
mg/l
0.11
21
218
116
1121
1.04
0.12
1.6
2.2
—
—
—
0
0
45
476
0.94
0.11
1.3
1.5
71.68
141.71
pmol/l
1.03
45
465
34
363
0.94
0.11
1.1
1.1
26.80
1374.63
iu/ml
—
5
98
46
485
0.95
0.10
1.1
1.2
3.64
3.75
mmol/l
0.35
41
455
51
485
1.05
0.10
1.2
1.4
356.07
1446.06
e6/l
0.97
44
402
53
555
0.95
0.10
3.0
2.0
3.28
4.31
iu/l
1.10
21
211
15
166
0.90
0.09
1.5
1.4
3277.80
1842.08
e6/l
—
10
118
5
46
1.09
0.09
1.2
1.1
—
—
—
0
0
5
47
1.06
0.09
1.6
1.3
62.28
69.18
mu/l
—
5
36
139
1356
1.03
0.09
1.3
1.3
85.74
46.49
au/ml
—
5
59
16
145
1.10
0.09
2.1
1.4
—
66.50
—
0
18
13
116
1.12
0.09
1.3
1.8
—
—
—
0
0
47
448
1.05
0.09
1.1
1.4
—
—
—
0
0
6
57
1.05
0.08
1.2
2.0
18.70
16.84
umol/l
—
6
57
16
175
0.91
0.08
2.9
2.7
—
—
—
0
0
6
70
0.86
0.07
2.3
1.2
—
—
—
0
0
6
74
0.81
0.07
1.3
1.5
—
—
—
0
0
8
76
1.05
0.07
1.7
1.3
—
—
—
0
0
39
407
0.96
0.06
1.7
1.7
—
—
—
0
0
16
173
0.92
0.06
1.5
1.5
0.84
0.95
g/l
0.91
16
173
42
437
0.96
0.06
2.5
2.6
108.11
130.31
ug/min
0.11
21
278
9
102
0.88
0.06
1.4
1.1
—
—
—
0
0
50
485
1.03
0.05
1.1
1.4
206.67
35.81
e6/l
0.39
43
387
51
522
0.98
0.03
1.5
3.0
—
—
—
0
0
12
112
1.07
0.03
1.2
1.4
139.92
139.00
nmol/l
0.05
12
112
33
322
1.03
0.01
2.3
3.1
—
—
—
0
0
109
1100
0.99
0.01
1.4
1.4
—
—
—
0
0
41
402
1.02
0.01
2.9
3.1
31.46
35.45
umol/l
0.63
35
349
147
1479
0.99
0.01
1.6
1.7
—
—
—
0
0
46
467
0.98
0.01
1.1
1.1
0.89
1.53
u/ml
0.43
17
187
65
643
1.01
0.01
10.7
8.3
—
—
—
0
0
44
446
0.99
0.00
1.3
1.5
0.31
0.42
nmol/l
0.68
39
365
15
151
0.99
0.00
1.5
2.1
—
—
—
0
0
15
151
0.99
0.00
1.0
1.0
0.44
0.94
u/ml
—
7
32
16
161
0.99
0.00
1.3
1.9
5.86
6.42
mmol/l
—
10
109
49
495
0.99
0.00
1.1
1.1
10.21
5.89
u/ml
0.53
20
262
53
535
0.99
0.00
1.1
1.1
1.69
1.50
u/ml
0.05
15
214
32
316
1.01
0.00
1.1
1.2
—
—
—
0
0
47
466
1.01
0.00
1.1
1.1
0.76
2.74
u/ml
—
8
105
34
342
0.99
0.00
1.0
1.0
0.74
0.39
u/ml
—
6
73
40
402
0.99
0.00
1.1
1.1
3.02
4.00
u/ml
0.26
12
144
165
1654
1.00
0.00
1.3
1.2
78.32
150.10
iu/ml
3.90
62
647
0
5
0.00
0.00
0.0
1.2
—
72.60
—
0
5
0
5
0.00
0.00
0.0
1.6
—
2923.32
—
0
5
0
5
0.00
0.00
0.0
1.2
—
118.81
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
99
0.91
0.00
1.3
2.5
1759.44
2016.02
ml
—
9
89
7
77
0.91
0.00
2.3
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
0.06
—
0
9
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.90
0.00
1.7
2.5
—
—
—
0
0
0
7
0.00
0.00
0.0
4.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
2.28
—
0
6
9
91
0.99
0.00
3.6
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint ULCERPROCT and mortality.

Females

Parameter HR [95% CI] p-value
ULCERPROCT 1.073 [0.94, 1.23] 0.305
Birth year 0.992 [0.98, 1.0] 0.067

During the follow-up period (1.1.1998 — 31.12.2019), 443 out of 6386 females with ULCERPROCT died.

Males

Parameter HR [95% CI] p-value
ULCERPROCT 1.054 [0.94, 1.18] 0.354
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 674 out of 5681 males with ULCERPROCT died.

Mortality risk

Mortality risk for people of age

years, who have ULCERPROCT.

N-year risk Females Males
1 0.095% 0.217%
5 0.556% 1.228%
10 1.432% 3.08%
15 2.668% 5.909%
20 4.512% 9.884%

Relationships between endpoints

Index endpoint: ULCERPROCT – Ulcerative proctitis

GWS hits: 9

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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