Nonspecific lymphadenitis

I9_LYMPHADE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I88
  • Hospital discharge: ICD-9 289[1-2]
  • Hospital discharge: ICD-8 289[1-3]
  • Cause of death: ICD-10 I88
  • Cause of death: ICD-9 289[1-2]
  • Cause of death: ICD-8 289[1-3]

2 out of 7 registries used, show all original rules.

2531

4. Check minimum number of events

None

2531

5. Include endpoints

None

2531

6. Filter based on genotype QC (FinnGen only)

2531

Control definitions (FinnGen only)

Control exclude
I9_DISVEINLYMPH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I80-I89
Name in latin
Lymphadenitis non specifica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 21458 12186 9189
Only index persons 19301 11160 8141
Unadjusted period prevalence (%)
Whole population 0.31 0.35 0.26
Only index persons 0.37 0.41 0.31
Median age at first event (years)
Whole population 18.15 19.68 16.00
Only index persons 17.89 19.42 15.79

-FinnGen-

Key figures

All Female Male
Number of individuals 2531 1686 845
Unadjusted period prevalence (%) 0.51 0.57 0.37
Median age at first event (years) 20.00 19.90 20.18

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2286
Matched controls
22858
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
28920
ICD-8 Finland
Other disease of blood and blood-forming organs, Nonspecific mesenteric lymphadenitis
+∞
323.0
1175
*
I88.9
ICD-10 Finland
Nonspecific lymphadenitis, unspecified
271.1
323.0
365
16
I88.0
ICD-10 Finland
Nonspecific mesenteric lymphadenitis
1624.8
297.4
283
*
28930
ICD-8 Finland
Other disease of blood and blood-forming organs, Lymphadenitis, unspecified, except mesenteric
+∞
210.7
199
*
28910
ICD-8 Finland
Other disease of blood and blood-forming organs, Chronic lymphadenitis
+∞
106.1
101
*
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
13.9
70.7
124
94
I88.8
ICD-10 Finland
Other nonspecific lymphadenitis
74.1
69.6
79
11
PHD99
NOMESCO Finland
Resection of other vein
347.2
67.9
68
*
4549X
ICD-9 Finland
Varicose veins of lower extremities, Without mention of ulcer or inflammation
+∞
56.5
54
*
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
+∞
53.3
51
*
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
7.4
53.0
131
187
PHD76
NOMESCO Finland
Resection of long saphenous vein
266.4
51.3
52
*
2892A
ICD-9 Finland
Other diseases of blood and blood-forming organs, Nonspecific mesenteric lymphadenitis
+∞
46.0
44
*
5611
FHL
Vena saphena Magna and / or swarm of nodule and possible local emissions
146.0
40.9
43
*
2891A
ICD-9 Finland
Other diseases of blood and blood-forming organs, Chronic lymphadenitis
+∞
35.5
34
*
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
352.4
35.0
35
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
34.6
839
5578
N02AX02
ATC
tramadol; systemic, rectal
1.7
29.3
902
6360
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
16.4
26.3
42
26
JEA00
NOMESCO Finland
Appendectomy
2.7
25.8
192
763
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
3.9
25.4
108
288
I88.1
ICD-10 Finland
Chronic lymphadenitis, except mesenteric
+∞
25.0
24
*
H02AB06
ATC
prednisolone; systemic
1.5
21.4
963
7309
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
5.9
20.9
59
103
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.7
19.7
138
530
PJA10
NOMESCO Finland
Exploration of lymph nodes
7.4
19.5
46
63
J01AA02
ATC
doxycycline; systemic
1.6
19.4
1702
14875
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
6.5
18.9
49
77
J01FF01
ATC
clindamycin; systemic
1.6
18.8
567
3867
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
16.0
18.8
30
19
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
18.2
484
3189
A02BC02
ATC
pantoprazole; systemic
1.5
18.2
1335
11119
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
8.6
18.2
39
46
J01DA01
ATC
[U] cefalexin; systemic
1.5
18.1
1364
11422
N03AX16
ATC
pregabalin; oral
1.7
18.0
485
3203
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
17.8
768
5700
J01FA10
ATC
azithromycin; systemic
1.5
17.6
1320
11007
5612
FHL
Local excisions and / or perforations of relapsing varicose veins
181.3
17.5
18
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
17.5
204
1014
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.3
17.4
89
278
4701
FHL
Neck lymph node removal
24.2
17.3
24
10
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
17.2
545
3755
J01MA02
ATC
ciprofloxacin; systemic
1.5
16.2
733
5471
P01AB01
ATC
metronidazole; oral, rectal
1.5
16.2
860
6639
N03AX12
ATC
gabapentin; oral
1.8
16.2
323
1952
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
6.2
15.8
42
69
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
15.3
159
750
R51.80
ICD-10 Finland
Headache
1.7
15.3
323
1983
R03AC02
ATC
salbutamol; inhalant
1.4
15.1
1118
9179
UJF32
NOMESCO Finland
Coloscopy
1.6
14.9
458
3115
J01MA12
ATC
levofloxacin; systemic
1.7
14.3
333
2098
R60.0
ICD-10 Finland
Localized oedema
2.0
14.0
176
901
M25.5
ICD-10 Finland
Pain in joint
1.5
14.0
597
4377
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
5.3
13.9
42
81
J01FA06
ATC
roxithromycin; oral
1.4
13.8
835
6564
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
2.9
13.7
84
297
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
13.7
449
3096
J01DB01
ATC
cefalexin; oral
1.5
13.7
1760
15878
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
13.7
339
2178
M79.6
ICD-10 Finland
Pain in limb
1.5
13.6
679
5133
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
34.2
13.5
17
5
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
13.5
468
3269
R01AD09
ATC
mometasone; nasal
1.4
13.4
983
7989
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
13.3
356
2333
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
13.1
478
3376
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.8
13.1
256
1530
JN4BD
NOMESCO Finland
Extensive body CT
1.9
13.1
186
1000
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
13.0
332
2149
J01FA09
ATC
clarithromycin; systemic
1.4
12.8
686
5249
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
12.8
169
882
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
12.7
740
5746
A02BC05
ATC
esomeprazole; systemic
1.4
12.7
811
6410
PHM99
NOMESCO Finland
Endovenous obliteration of other vein
+∞
12.5
12
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
12.4
299
1903
M01AH01
ATC
celecoxib; oral (coxibs)
1.6
12.3
343
2267
N02BE01
ATC
paracetamol; systemic, rectal
1.5
12.2
1805
16476
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
7.8
12.1
27
35
R07.3
ICD-10 Finland
Other chest pain
2.0
12.1
166
880
N02AA05
ATC
oxycodone; systemic
1.8
12.1
211
1219
R50.9
ICD-10 Finland
Fever, unspecified
1.7
12.0
264
1632
A02BC01
ATC
omeprazole; systemic
1.5
11.8
503
3665
M03BX02
ATC
tizanidine; oral
1.4
11.6
1355
11792
A46
ICD-10 Finland
Erysipelas
1.8
11.6
214
1256
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
11.3
213
1261
C82.1
ICD-10 Finland
Follicular lymphoma grade II
8.9
11.2
23
26
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
11.2
945
7786
ZXA00
NOMESCO Finland
Right side
1.5
11.2
459
3312
R05FA02
ATC
opium derivatives and expectorants; systemic
1.4
11.2
794
6358
WX110
NOMESCO Finland
Local anesthesy
1.4
11.2
1459
12892
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
11.1
660
5118
J01CA04
ATC
amoxicillin; systemic
1.4
11.1
1744
15894
I88
ICD-10 Finland
Nonspecific lymphadenitis
13.9
11.0
18
13
R06.0
ICD-10 Finland
Dyspnoea
1.5
10.9
412
2921
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
10.9
923
7601
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
2.5
10.9
81
326
R03AC03
ATC
terbutaline; inhalant
1.6
10.7
288
1886
N06AA09
ATC
amitriptyline; systemic
1.8
10.7
188
1089
J02AC01
ATC
fluconazole; systemic
1.4
10.3
874
7179
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
10.2
317
2147
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
10.2
235
1473
M01AE02
ATC
naproxen; oral, rectal
1.3
10.2
1186
10221
N06AX16
ATC
venlafaxine; oral
1.6
10.1
304
2043
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
14.6
10.0
16
11
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
6.7
9.9
24
36
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
9.9
314
2138
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
9.7
395
2836
A02BA02
ATC
ranitidine; systemic
1.5
9.7
346
2418
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
13.4
9.7
16
12
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
9.5
313
2150
R06AE07
ATC
cetirizine; oral
1.3
9.5
901
7505
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
9.4
493
3719
PHD78
NOMESCO Finland
Resection of communicating veins of lower leg and thigh
100.4
9.4
10
*
E0000UV
ATC
NA
1.3
9.4
747
6051
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.7
9.3
178
1059
ZXA05
NOMESCO Finland
Left side
1.4
9.2
423
3111
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
9.2
322
2237
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
9.2
405
2956
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
9.2
1012
8602
R42
ICD-10 Finland
Dizziness and giddiness
1.5
9.1
359
2562
R03BA05
ATC
fluticasone; inhalant
1.5
8.9
349
2486
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
18.7
8.9
13
7
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
8.0
8.8
19
24
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
8.8
786
6467
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
8.7
219
1409
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
14.1
8.7
14
10
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
14.1
8.7
14
10
A01AB09
ATC
miconazole; local oral
1.8
8.6
158
928
M79.7
ICD-10 Finland
Fibromyalgia
2.3
8.6
80
360
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
8.6
251
1674
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
8.6
723
5888
C07AB07
ATC
bisoprolol; oral
1.3
8.6
729
5950
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
4.6
8.5
28
62
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
8.4
511
3947
TPH10
NOMESCO Finland
Sclerotherapy of varicose veins
90.4
8.4
9
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.4
1514
13703
WX002
NOMESCO Finland
Sedation and analgesia
1.5
8.4
326
2319
PHM79
NOMESCO Finland
Endovenous obliteration of v.saphena anterior
+∞
8.3
8
*
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
+∞
8.3
8
*
M01AC06
ATC
meloxicam; systemic, rectal
1.3
8.3
713
5823
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.9
8.2
110
581
N05AH04
ATC
quetiapine; oral
1.5
8.2
324
2309
H02AB07
ATC
prednisone; oral
1.5
8.2
256
1734
R03BB04
ATC
tiotropium bromide; inhalant
1.8
8.1
143
829
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
8.1
128
716
M02AA07
ATC
piroxicam; topical
1.3
8.1
649
5239
R02
ICPC
Shortness of breath/dyspnoea
1.6
8.1
189
1193
N06AX21
ATC
duloxetine; oral
1.6
8.1
215
1401
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
7.9
382
2829
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
7.9
306
2174
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
7.8
89
440
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
7.8
127
717
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
7.8
337
2447
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.0
7.8
100
522
M01AB05
ATC
diclofenac; systemic, rectal
1.3
7.7
1380
12398
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
7.7
241
1631
R03DC03
ATC
montelukast; oral
1.4
7.7
325
2352
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
7.6
1989
18862
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
7.6
495
3862
J05AB01
ATC
aciclovir; systemic
1.4
7.5
392
2948
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.6
7.5
180
1146
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.6
7.5
32
91
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
7.4
612
4951
N05BA04
ATC
oxazepam; oral
1.4
7.4
448
3452
N07BB01
ATC
disulfiram; oral
2.0
7.3
90
460
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.8
7.3
132
772
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.4
7.3
59
252
PHM77
NOMESCO Finland
Endovenous obliteration of v.saphena parva
+∞
7.3
7
*
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
7.3
1140
10040
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
2.7
7.3
47
177
N30.0
ICD-10 Finland
Acute cystitis
1.5
7.2
225
1526
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
7.2
148
902
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
7.1
476
3725
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
7.1
187
1215
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
7.1
202
1338
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.8
7.1
123
712
N06AX11
ATC
mirtazapine; oral
1.3
7.1
590
4773
AA1AD
NOMESCO Finland
CT of head and brain
1.4
7.1
354
2640
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
3.9
7.1
27
70
A06AD11
ATC
lactulose; oral
1.6
7.1
194
1277
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
7.0
565
4548
L04.9
ICD-10 Finland
Acute lymphadenitis, unspecified
8.8
7.0
14
16
R05
ICD-10 Finland
Cough
1.4
7.0
339
2511
C03CA01
ATC
furosemide; systemic
1.4
7.0
318
2328
61207
ICD-8 Finland
Acute salpingitis and oophoritis, suspecta
3.7
7.0
28
76
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
2.2
6.9
69
324
J01FA01
ATC
erythromycin; systemic
1.5
6.9
282
2019
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.8
6.9
105
582
R53
ICD-10 Finland
Malaise and fatigue
1.4
6.9
331
2449
B02
ICPC
Lymph gland(s) enlarged/painful
4.6
6.9
22
48
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
6.8
202
1350
G44.2
ICD-10 Finland
Tension-type headache
1.5
6.8
252
1769
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
6.8
167
1067
75100
ICD-8 Finland
Other congenital anomalies of digestive system, Meckel's diverticulum
40.2
6.8
8
*
A03
ICPC
Fever
1.4
6.8
305
2230
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
6.7
382
2909
L12
ICPC
Hand/finger symptom/complaint
1.5
6.7
249
1753
N05CF01
ATC
zopiclone; oral
1.3
6.7
546
4402
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.0
6.7
83
429
A02BC03
ATC
lansoprazole; oral
1.3
6.7
528
4237
A03FA02
ATC
cisapride; oral, rectal
1.7
6.6
124
736
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.6
6.6
44
170
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
4.2
6.6
23
55
R11
ICD-10 Finland
Nausea and vomiting
1.7
6.6
129
776
R59
ICD-10 Finland
Enlarged lymph nodes
12.3
6.6
11
9
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.8
6.5
39
141
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
1.8
6.5
100
558
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.5
1046
9188
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.7
6.5
128
772
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
70.0
6.4
7
*
B01AB05
ATC
enoxaparin; parenteral
1.3
6.4
461
3644
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
7.4
6.4
14
19
J01MA14
ATC
moxifloxacin; systemic
1.6
6.4
145
908
A03CA02
ATC
clidinium and psycholeptics; oral
1.9
6.4
93
511
R52.0
ICD-10 Finland
Acute pain
2.2
6.3
60
278
M01AH05
ATC
etoricoxib; oral
1.2
6.3
1214
10872
7856A
ICD-9 Finland
Symptoms involving cardiovascular system, Enlargement of lymph nodes
9.3
6.3
12
13
N06AB03
ATC
fluoxetine; oral
1.5
6.3
241
1708
I87.0
ICD-10 Finland
Postthrombotic syndrome
+∞
6.3
6
*
M01AX17
ATC
nimesulide; oral
1.3
6.1
403
3140
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
4.2
6.1
21
50
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
6.1
519
4201
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.0
6.1
72
367
R78
ICPC
Acute bronchitis/bronchiolitis
2.6
6.0
41
162

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1270
9995
1.54
24.71
6.6
6.0
10.3
10.7
umol/l
0.62
1211
9496
644
4394
1.62
23.02
4.9
4.1
—
—
—
0
0
1771
15148
1.56
22.48
4.8
3.8
10.4
10.7
mm/h
0.55
1693
14155
629
4338
1.60
21.25
1.8
1.8
1.0
0.9
mg/l
0.27
473
3234
1781
15339
1.54
21.11
8.2
7.1
76.2
76.7
u/l
0.20
1692
14502
1291
10460
1.48
20.18
7.4
6.1
0.2
0.2
e9/l
1.04
1158
9261
1253
10097
1.48
20.11
7.0
5.9
0.0
0.0
e9/l
0.84
1111
8782
1179
9408
1.47
19.76
7.3
6.0
2.9
2.8
%
0.46
1116
8786
1350
11074
1.47
19.56
5.3
4.4
6.5
6.6
mmol/l
0.97
1281
10265
1245
10061
1.47
19.44
7.0
5.9
0.6
0.6
e9/l
1.34
1108
8751
1146
9115
1.47
19.41
7.4
6.1
0.7
0.7
%
0.96
1088
8525
1274
10372
1.46
18.95
7.1
5.9
2.0
2.0
e9/l
0.37
1147
9219
67
199
3.43
18.92
1.5
1.2
—
—
—
0
0
1178
9472
1.46
18.56
7.6
6.3
8.4
8.4
%
0.11
1123
8904
862
6530
1.49
18.43
6.8
6.0
—
—
—
0
0
812
6079
1.49
18.41
3.0
2.4
55.2
56.7
u/l
0.46
755
5665
887
6776
1.48
18.11
7.4
6.6
1.1
1.2
inr
1.03
296
2012
1403
11702
1.45
17.94
10.4
9.0
4.1
4.0
e9/l
0.45
1259
10253
1205
9781
1.44
17.77
7.3
6.0
29.6
29.2
%
0.71
1146
9150
1192
9667
1.44
17.60
7.0
5.8
55.9
56.4
%
0.80
1133
9076
878
6728
1.47
17.49
3.5
3.0
27.4
38.7
ng/l
0.88
497
3941
1122
9038
1.43
16.98
7.3
6.4
1.2
1.2
mmol/l
0.20
963
7698
731
5460
1.48
16.37
2.0
2.1
177.2
223.9
u/l
0.83
690
5186
525
3680
1.54
15.91
2.8
2.4
6.1
6.4
e6/l
0.14
474
3226
387
2528
1.63
15.88
2.2
2.0
—
—
—
0
0
251
1511
1.73
13.98
3.5
2.6
10.0
10.3
g/l
0.58
226
1385
707
5414
1.42
13.37
3.5
2.9
28.0
89.2
e6/l
2.49
574
4075
976
7898
1.38
13.36
4.9
4.6
36.3
36.4
g/l
0.29
909
7391
2246
20983
1.63
13.20
15.9
11.6
19.5
21.6
mg/l
2.82
1850
16208
826
6531
1.39
12.89
3.9
3.4
81.2
81.2
e6/l
0.00
629
4455
204
1187
1.78
12.78
2.1
1.8
1.2
1.3
g/l
0.64
188
1101
476
3408
1.49
12.75
3.7
3.3
433.2
457.8
ng/l
0.04
332
2345
988
8106
1.36
12.05
6.6
5.7
1.2
1.2
mmol/l
0.19
908
7392
647
4958
1.41
11.97
3.4
2.9
0.3
0.4
e6/l
0.42
511
3656
1082
9010
1.35
11.95
11.5
8.5
0.0
0.0
e9/l
0.15
905
7368
567
4250
1.43
11.86
2.6
2.8
801.8
969.4
ng/l
0.78
480
3515
1097
9174
1.35
11.69
4.1
3.7
—
—
—
0
0
625
4809
1.40
11.17
5.1
4.4
—
—
—
0
0
678
5309
1.38
10.86
4.0
3.8
7.4
7.4
ph
0.49
137
980
461
3389
1.44
10.60
3.1
2.6
533.1
548.6
mosm/kgh2o
0.72
400
2894
784
6304
1.35
10.56
3.5
3.3
2.4
2.4
mmol/l
0.64
709
5643
1442
12680
1.32
10.31
4.7
3.9
2011.3
1920.6
e6/l
0.02
26
156
542
4125
1.40
10.22
1.9
1.9
—
—
—
0
0
625
4911
1.36
9.62
3.4
2.8
—
—
—
0
0
406
2972
1.44
9.48
1.5
1.3
486.1
530.6
titre
0.22
79
595
2249
21294
1.50
9.37
16.2
12.6
139.6
139.7
mmol/l
2.07
2204
20791
1525
13605
1.30
9.35
4.7
3.9
—
—
—
0
0
550
4253
1.37
9.32
1.6
1.4
2.2
2.3
g/l
1.18
378
2699
2256
21381
1.51
9.28
16.3
12.7
4.0
3.9
mmol/l
0.56
2207
20835
399
2924
1.43
9.25
3.7
3.6
0.8
0.8
mmol/l
0.66
371
2753
234
1538
1.57
9.20
5.1
4.4
0.1
0.2
%
0.99
70
387
652
5196
1.34
9.07
3.1
2.7
—
—
—
0
0
242
1612
1.55
8.98
5.0
4.3
0.9
0.8
%
0.10
72
420
73
339
2.19
8.84
1.7
1.6
1.0
0.8
g/l
0.65
54
265
52
208
2.53
8.81
1.4
1.3
6.9
6.5
g/l
0.32
37
151
351
2544
1.44
8.61
1.7
1.6
—
—
—
0
0
406
3025
1.41
8.53
2.8
2.5
1.1
1.0
e6/l
0.13
237
1656
1637
14876
1.28
8.03
3.5
3.0
51.3
44.5
u/l
1.97
1546
14079
377
2807
1.40
7.93
3.0
2.7
3.8
3.0
e6/l
0.58
208
1443
50
208
2.43
7.84
1.5
1.3
3.0
2.9
g/l
0.17
36
151
50
208
2.43
7.84
1.5
1.3
0.4
0.4
g/l
0.71
35
149
1051
9068
1.27
7.82
2.9
2.8
114.3
109.9
ug/l
0.28
991
8536
128
753
1.74
7.78
1.5
1.5
5.5
21.1
u/ml
—
5
15
216
1450
1.54
7.74
5.3
4.4
0.1
0.3
%
0.35
54
325
220
1483
1.53
7.74
4.8
4.1
0.3
0.5
%
1.20
52
310
371
2766
1.40
7.73
1.3
1.2
—
—
—
0
0
1133
9885
1.26
7.62
4.0
3.3
0.0
0.0
estimate
1.32
213
1713
265
1863
1.47
7.61
13.2
17.3
1.2
1.2
inr
0.18
58
282
305
2204
1.44
7.58
1.8
1.6
—
—
—
0
0
604
4885
1.31
7.36
1.3
1.3
1.6
2.0
u/ml
0.36
182
1329
623
5066
1.30
7.29
2.7
2.3
2941.4
4027.5
umol/l
0.39
564
4490
362
2717
1.39
7.23
2.3
2.4
14.0
14.1
umol/l
0.09
332
2534
308
2256
1.42
7.09
2.4
2.5
23.4
24.2
%
0.42
256
1960
1114
9770
1.25
6.94
4.0
3.3
0.0
0.0
estimate
0.50
213
1730
491
3887
1.33
6.93
1.3
1.3
26.8
28.5
iu/ml
0.11
147
1253
120
718
1.70
6.90
1.3
1.2
—
—
—
0
0
410
3166
1.35
6.84
2.9
2.9
2.4
2.4
mmol/l
0.02
364
2784
625
5123
1.29
6.82
8.2
6.6
—
—
—
0
0
355
2683
1.38
6.79
2.1
2.4
113.7
121.9
ug/g
0.26
281
2150
1924
18001
1.29
6.66
18.3
14.2
13.6
13.6
%
0.01
1890
17631
329
2464
1.39
6.64
2.3
2.4
2.4
2.4
g/l
0.18
300
2304
48
212
2.29
6.64
1.5
1.3
—
—
—
0
0
237
1675
1.46
6.62
1.5
1.4
—
—
—
0
0
549
4441
1.30
6.60
2.2
2.1
2.7
2.8
mg/l
0.86
476
3831
53
245
2.19
6.58
1.3
1.2
—
—
—
0
0
1112
9790
1.24
6.57
5.4
4.5
0.0
0.0
estimate
0.80
224
1788
210
1456
1.48
6.47
1.4
1.3
207.8
208.7
u/ml
0.01
185
1348
845
7240
1.25
6.31
1.9
1.8
95.6
97.5
pmol/l
0.61
461
3755
2335
22528
1.47
6.26
16.7
13.1
72.8
72.9
umol/l
0.03
2335
22520
428
3369
1.33
6.24
1.6
1.6
—
—
—
0
0
298
2219
1.39
6.23
1.3
1.3
—
—
—
0
0
256
1862
1.42
6.13
7.3
8.2
1.2
1.0
mmol/l
0.31
191
1473
68
357
1.93
6.04
2.6
2.2
130.9
131.9
g/l
0.11
53
259
299
2241
1.38
6.00
3.0
2.6
8.1
7.3
umol/l
0.22
246
1943
178
1213
1.50
5.98
2.8
2.9
197.2
146.5
ng/l
0.43
167
1090
466
3733
1.30
5.97
1.3
1.3
12.9
9.9
u/ml
0.34
177
1555
255
1863
1.41
5.96
7.4
8.2
5.1
5.1
kpa
0.03
243
1787
255
1864
1.41
5.94
7.4
8.2
12.2
12.8
kpa
1.33
241
1790
296
2220
1.38
5.92
5.8
6.0
1.1
1.0
mmol/l
0.81
281
2070
78
432
1.83
5.89
1.3
1.5
—
—
—
0
0
53
257
2.08
5.87
2.7
2.4
—
—
—
0
0
708
5993
1.25
5.79
2.3
2.2
—
—
—
0
0
1553
14276
1.23
5.75
3.6
3.2
—
—
—
0
0
236
1712
1.42
5.74
2.8
2.9
1.7
1.8
%
0.23
210
1544
19
55
3.47
5.73
1.3
1.1
—
—
—
0
0
200
1412
1.45
5.64
5.2
3.6
1.2
1.2
mmol/l
0.11
181
1230
190
1331
1.46
5.58
1.9
2.2
5.5
8.2
ug/l
1.46
167
1197
228
1653
1.42
5.57
2.5
2.2
0.2
0.2
g/l
0.51
217
1563
206
1467
1.44
5.55
6.9
3.8
2.3
1.9
mmol/l
0.98
171
1194
64
341
1.90
5.47
4.6
3.6
—
—
—
0
0
612
5130
1.25
5.40
3.8
3.3
—
—
—
0
0
227
1654
1.41
5.39
7.8
8.8
95.6
96.0
%
0.30
217
1596
337
2617
1.33
5.37
2.3
2.2
29.4
29.4
s
0.05
327
2547
470
3819
1.28
5.37
1.5
1.5
19.5
21.1
nmol/l
1.89
419
3344
81
468
1.75
5.35
1.3
1.3
—
6.6
—
0
10
247
1830
1.39
5.33
2.8
2.5
36.1
66.0
u/l
0.60
212
1582
72
404
1.81
5.25
1.3
1.4
114.0
114.7
u/ml
0.02
14
82
581
4861
1.25
5.19
4.6
3.7
95.3
95.6
%
0.11
564
4739
215
1564
1.41
5.16
8.2
9.0
122.3
123.4
g/l
0.32
202
1512
176
1236
1.46
5.12
2.6
2.8
66.3
72.1
e9/l
1.48
133
937
203
1471
1.41
4.99
7.0
3.8
5.9
5.8
kpa
0.70
196
1424
92
563
1.66
4.96
2.0
2.3
12.4
11.5
mg/l
0.16
87
528
103
652
1.60
4.86
1.9
1.7
0.2
0.2
g/l
0.19
98
615
157
1097
1.46
4.71
1.2
1.1
23.3
152.7
titre
—
6
36
2332
22629
1.39
4.70
11.4
9.4
28.6
27.0
u/l
0.82
2275
21977
354
2827
1.29
4.60
1.8
1.7
1131.5
1161.5
nmol/l
0.26
278
2224
128
865
1.51
4.54
1.4
1.3
0.2
1.0
u/ml
—
8
73
642
5500
1.22
4.53
3.8
2.9
—
—
—
0
0
1748
16430
1.21
4.49
4.4
4.0
14.5
14.6
pmol/l
0.27
1630
15218
956
8521
1.20
4.45
2.1
2.0
—
—
—
0
0
91
574
1.61
4.39
1.1
1.1
—
—
—
0
0
300
2361
1.31
4.35
1.6
1.5
—
—
—
0
0
169
1218
1.42
4.32
7.5
3.2
4.6
4.7
kpa
0.35
163
1174
73
437
1.69
4.32
1.3
1.2
273.4
265.5
u/ml
0.09
47
266
116
779
1.51
4.26
1.2
1.2
—
—
—
0
0
2028
19387
1.23
4.18
5.1
4.6
1.8
2.1
mu/l
1.76
1908
18061
2293
22248
1.33
4.14
13.8
10.8
—
—
—
0
0
174
1276
1.39
4.04
2.5
2.6
65.8
67.1
g/l
1.33
162
1191
222
1694
1.34
4.01
1.6
1.4
—
—
—
0
0
145
1032
1.43
3.99
4.3
5.7
—
—
—
0
0
266
2087
1.31
3.96
9.8
7.1
104.4
104.4
mmol/l
0.01
255
2045
81
512
1.60
3.91
1.8
1.4
268.4
299.8
ug/g
0.72
49
290
191
1433
1.36
3.86
7.7
8.5
8.9
8.5
mmol/l
0.33
178
1377
100
666
1.52
3.85
2.6
2.2
21.0
21.3
s
0.27
86
576
597
5166
1.20
3.73
4.5
3.6
0.0
0.0
estimate
1.28
213
1738
45
245
1.85
3.71
4.2
3.3
1.0
1.1
%
0.19
33
200
846
7558
1.18
3.67
3.7
3.1
—
5.8
—
0
8
143
1032
1.41
3.67
9.5
8.0
24.5
24.8
mmol/l
0.44
143
1026
241
1887
1.31
3.65
2.4
2.1
375.3
374.1
nmol/l
0.03
226
1744
142
1025
1.41
3.64
6.0
7.5
24.7
24.5
mmol/l
0.20
129
947
56
328
1.72
3.63
3.6
2.4
16.6
16.6
%
0.04
32
170
98
661
1.50
3.58
5.7
6.5
1.7
1.7
%
0.22
87
615
37
191
1.95
3.58
1.7
1.4
—
—
—
0
0
528
4540
1.21
3.51
2.3
2.2
—
—
—
0
0
30
145
2.08
3.47
3.2
2.9
948.3
681.3
e6/l
—
8
59
38
201
1.90
3.44
3.4
2.6
1.5
1.2
e9/l
0.91
27
123
59
357
1.67
3.42
4.3
4.0
2.9
2.5
mmol/l
0.59
43
238
59
358
1.66
3.39
4.3
4.0
5.0
5.0
kpa
0.01
59
353
20
82
2.45
3.38
1.3
1.1
—
—
—
0
0
59
359
1.66
3.36
4.3
4.0
9.4
8.7
kpa
0.70
59
354
84
557
1.53
3.34
1.3
1.2
136.7
144.4
titre
0.05
15
48
129
935
1.40
3.26
2.1
2.3
—
—
—
0
0
187
1438
1.32
3.25
1.2
1.2
—
—
—
0
0
141
1039
1.38
3.23
2.1
2.3
—
—
—
0
0
2426
23840
1.42
3.17
22.3
17.1
91.0
90.6
fl
3.51
2409
23566
95
656
1.47
3.13
5.9
6.6
0.9
0.9
%
0.08
87
611
2426
23844
1.42
3.13
22.4
17.2
4.5
4.5
e12/l
5.14
2379
23267
2424
23821
1.42
3.13
22.4
17.2
259.8
259.0
e9/l
0.23
2383
23287
121
875
1.40
3.11
4.2
3.0
—
—
—
0
0
73
478
1.54
3.10
1.4
1.3
—
—
—
0
0
162
1230
1.34
3.08
3.0
2.6
—
—
—
0
0
489
4225
1.20
3.07
4.2
3.6
1.0
1.0
kg/l
1.18
76
600
2425
23839
1.41
3.05
22.3
17.1
30.3
30.2
pg
2.30
2408
23564
66
424
1.57
3.05
4.1
4.0
7.4
7.4
ph
0.17
59
352
2426
23851
1.41
3.05
22.5
17.3
135.8
136.7
g/l
2.88
2409
23577
447
3833
1.20
3.04
1.8
1.6
77428257.9
39667600.8
pmol/l
0.38
381
3305
125
914
1.39
3.02
10.0
11.3
—
—
—
0
0
56
347
1.63
3.00
2.6
3.7
—
—
—
0
0
183
1420
1.31
3.00
3.3
3.3
4.6
4.5
pmol/l
0.20
170
1272
303
2506
1.24
2.96
1.5
1.4
—
—
—
0
0
31
162
1.92
2.95
3.8
2.1
78.2
72.9
%
1.83
31
157
2425
23850
1.40
2.93
22.5
17.2
6.8
6.6
e9/l
1.37
2379
23271
50
305
1.65
2.86
1.7
1.6
—
—
—
0
0
49
298
1.66
2.84
1.2
1.2
5.2
4.8
u/ml
0.05
23
119
62
400
1.56
2.84
5.2
3.7
—
—
—
0
0
32
172
1.87
2.81
1.2
1.3
0.2
0.2
u/ml
0.22
16
72
33
180
1.84
2.78
2.6
5.6
6.5
7.2
mmol/l
0.62
25
150
48
293
1.65
2.75
1.8
1.4
—
—
—
0
0
108
785
1.39
2.73
9.7
4.2
24.3
24.3
mmol/l
0.00
98
719
31
167
1.87
2.71
1.6
1.5
32.0
31.3
%
0.03
16
98
30
160
1.89
2.71
3.9
2.0
11.5
12.6
%
0.20
12
73
132
995
1.34
2.67
7.8
3.2
129.1
130.1
g/l
0.21
127
973
89
628
1.43
2.67
2.0
2.8
—
—
—
0
0
82
570
1.45
2.66
3.3
3.7
1.3
1.3
mmol/l
0.02
82
559
32
176
1.83
2.64
1.8
2.5
—
—
—
0
0
115
851
1.37
2.63
10.1
10.6
24.1
24.3
mmol/l
0.25
107
811
19
87
2.19
2.57
2.1
2.0
—
—
—
0
0
19
87
2.19
2.57
2.3
2.8
—
—
—
0
0
8
20
4.01
2.56
1.3
1.1
—
—
—
0
0
62
412
1.52
2.52
3.5
3.0
24.2
24.8
mmol/l
0.72
55
363
80
560
1.44
2.52
5.6
7.7
1.1
1.3
mmol/l
1.76
69
490
46
286
1.62
2.49
3.8
2.5
—
—
—
0
0
102
748
1.38
2.48
8.3
2.8
0.6
0.7
%
0.10
97
722
82
579
1.43
2.47
1.5
1.2
5.2
3.0
u/ml
—
7
55
308
2604
1.21
2.45
1.3
1.2
—
—
—
0
0
183
1463
1.27
2.43
3.4
3.2
—
—
—
0
0
20
96
2.09
2.43
2.2
2.7
—
—
—
0
0
172
1373
1.27
2.33
11.3
8.9
—
—
—
0
0
70
487
1.45
2.30
3.2
3.8
3.9
3.8
mmol/l
0.54
64
454
648
5848
1.15
2.30
1.5
1.5
—
—
—
0
0
35
207
1.70
2.30
2.9
2.4
—
—
—
0
0
47
301
1.57
2.28
5.2
5.7
358.9
371.7
umol/l
0.25
40
268
27
149
1.82
2.24
1.3
1.1
—
—
—
0
0
62
424
1.47
2.23
1.9
1.5
—
—
—
0
0
18
86
2.10
2.22
1.9
2.1
—
—
—
0
0
14
60
2.34
2.21
1.1
1.5
—
—
—
0
0
5
9
5.56
2.21
1.0
1.0
—
—
—
0
0
113
863
1.32
2.15
1.7
2.0
—
—
—
0
0
110
837
1.33
2.15
1.7
1.7
—
—
—
0
0
6
14
4.29
2.15
1.2
1.0
—
—
—
0
0
6
14
4.29
2.15
1.2
1.0
—
—
—
0
0
116
891
1.32
2.13
1.1
1.1
—
—
—
0
0
84
615
1.38
2.11
2.3
2.1
5.6
2.2
ug/l
0.61
74
553
186
1519
1.24
2.10
2.4
2.3
35.2
18.9
au/ml
0.49
11
98
256
2163
1.20
2.07
1.5
1.4
—
—
—
0
0
501
4479
1.15
2.03
3.9
3.3
—
—
—
0
0
13
57
2.29
1.97
3.5
3.1
—
—
—
0
0
65
461
1.42
1.97
1.9
1.4
28.3
14.2
e6/l
0.42
52
362
65
461
1.42
1.97
2.0
1.5
499.4
1119.4
e6/l
0.63
57
378
59
412
1.44
1.95
2.0
1.7
11149.2
11771.4
e6/l
0.06
41
304
43
282
1.53
1.92
1.3
1.2
—
—
—
0
0
152
1228
1.25
1.91
1.3
1.2
—
—
—
0
0
16
78
2.06
1.91
1.1
1.7
—
—
—
0
0
13
58
2.25
1.90
1.2
1.0
—
—
—
0
0
170
1392
1.24
1.90
1.3
1.3
34.9
44.0
au/ml
—
8
64
80
593
1.36
1.89
1.2
1.2
—
—
—
0
0
33
205
1.62
1.86
1.2
1.1
—
—
—
0
0
61
434
1.42
1.84
2.4
3.5
1.8
2.5
ratio
—
9
52
120
947
1.28
1.84
1.7
2.0
—
—
—
0
0
55
384
1.44
1.84
1.1
1.1
—
—
—
0
0
25
145
1.73
1.81
3.2
3.1
51.2
55.8
%
0.37
14
100
1954
18983
1.13
1.81
5.2
5.0
39.0
39.0
mmol/mol
0.08
1844
17840
45
303
1.49
1.80
1.4
1.7
—
—
—
0
0
7
23
3.05
1.80
1.6
1.0
—
—
—
0
0
50
345
1.46
1.78
1.3
1.2
—
—
—
0
0
130
1041
1.26
1.78
3.7
3.4
5.2
5.2
kpa
0.02
125
975
119
943
1.27
1.77
1.7
2.0
—
—
—
0
0
128
1024
1.26
1.77
3.7
3.4
7.4
7.4
ph
0.28
22
128
57
404
1.42
1.77
4.5
3.8
55.6
56.8
%
0.30
57
404
36
232
1.56
1.76
2.3
2.8
3.7
56.8
u/ml
0.51
36
218
62
447
1.40
1.75
2.6
3.6
38.7
60.2
mg/l
0.78
45
355
167
1380
1.22
1.73
1.7
1.4
—
—
—
0
0
62
448
1.39
1.73
2.7
3.6
24.7
36.0
mg/l
0.91
45
358
74
551
1.35
1.72
1.5
2.4
228.6
401.6
ug/l
0.99
68
506
118
938
1.27
1.72
1.7
2.0
—
—
—
0
0
24
140
1.72
1.72
1.5
1.3
—
—
—
0
0
28
171
1.64
1.70
1.4
1.5
2.2
1.3
promille
1.45
19
132
23
133
1.74
1.70
1.3
1.1
—
—
—
0
0
31
195
1.60
1.68
2.9
2.2
31.5
32.5
pg
0.50
31
195
24
141
1.71
1.68
1.0
1.0
—
—
—
0
0
42
284
1.49
1.67
1.6
1.4
—
—
—
0
0
16
83
1.93
1.64
1.9
2.7
—
—
—
0
0
84
643
1.32
1.64
1.5
1.8
1.5
1.6
g/l
0.51
74
556
112
891
1.27
1.64
1.5
1.6
282.4
294.7
mu/l
0.15
101
799
28
173
1.63
1.64
1.3
1.2
31.0
39.2
mg/l
0.88
23
143
159
1318
1.22
1.62
3.7
3.6
83.5
80.1
ng/l
0.25
132
1163
5
14
3.58
1.61
1.0
1.1
—
—
—
0
0
54
388
1.40
1.58
6.6
9.4
10.8
11.4
mmol/l
1.01
47
349
54
389
1.40
1.56
6.6
9.3
105.3
105.3
mmol/l
0.00
47
350
61
450
1.36
1.54
2.2
2.0
—
—
—
0
0
18
100
1.81
1.53
1.0
1.1
122.5
192.7
iu/ml
1.00
18
100
15
79
1.90
1.49
1.3
1.7
—
—
—
0
0
115
930
1.25
1.49
1.8
1.9
—
—
—
0
0
199
1702
1.18
1.47
3.4
3.9
—
—
—
0
0
10
45
2.23
1.46
1.4
2.2
641.6
3579.7
e6/l
—
5
26
7
28
2.50
1.45
1.1
1.1
—
—
—
0
0
203
1742
1.18
1.45
1.2
1.2
—
—
—
0
0
52
378
1.38
1.44
13.7
3.3
—
—
—
0
0
25
156
1.61
1.43
1.3
1.1
215.0
174.4
titre
—
8
34
31
204
1.53
1.43
2.4
2.3
—
—
—
0
0
18
103
1.75
1.40
3.8
3.0
39.2
43.9
%
—
5
30
51
372
1.38
1.40
1.1
1.1
—
—
—
0
0
109
884
1.24
1.39
2.2
2.2
7144.7
4146.3
u/l
0.34
38
355
7
29
2.42
1.39
3.4
2.1
—
—
—
0
0
34
230
1.48
1.39
2.5
2.6
—
—
—
0
0
28
182
1.54
1.37
1.3
1.4
11.6
11.9
mmol/l
—
10
43
60
451
1.34
1.37
1.3
1.2
—
—
—
0
0
24
151
1.60
1.34
1.0
1.0
—
—
—
0
0
189
1627
1.17
1.32
4.8
3.6
—
—
—
0
0
81
639
1.28
1.32
3.8
4.3
—
—
—
0
0
6
24
2.50
1.30
1.5
1.1
—
—
—
0
0
21
129
1.63
1.30
2.4
2.8
600.7
818.5
u/ml
0.65
21
129
49
361
1.36
1.28
3.5
2.9
37.2
36.1
umol/l
0.09
44
316
25
161
1.56
1.28
1.2
1.1
—
—
—
0
0
5
18
2.78
1.28
1.8
1.1
—
—
—
0
0
32
219
1.47
1.26
1.7
1.5
—
—
—
0
0
32
219
1.47
1.26
1.7
1.5
—
—
—
0
0
32
219
1.47
1.26
1.7
1.5
—
—
—
0
0
32
219
1.47
1.26
1.7
1.5
—
—
—
0
0
75
591
1.28
1.24
3.0
3.5
40.2
442.1
u/ml
1.08
66
501
19
115
1.66
1.24
1.2
1.4
5.6
5.8
mmol/l
0.19
19
110
22
139
1.59
1.23
4.3
7.0
—
—
—
0
0
53
400
1.33
1.21
2.3
2.6
—
—
—
0
0
31
213
1.46
1.20
3.8
4.9
54.5
49.7
u/ml
—
8
65
20
125
1.60
1.17
1.4
1.3
—
—
—
0
0
35
248
1.42
1.17
1.5
2.2
5.3
5.7
umol/l
0.10
26
171
199
1740
1.16
1.16
3.2
4.0
4.2
19.6
ug/l
2.05
149
1376
53
405
1.32
1.12
1.2
1.2
—
—
—
0
0
76
609
1.26
1.12
1.1
1.1
—
—
—
0
0
17
103
1.65
1.12
1.1
1.2
28.6
35.2
mmol/l
0.61
17
95
26
176
1.48
1.10
5.6
3.8
—
—
—
0
0
5
21
2.38
1.09
2.4
2.1
—
—
—
0
0
167
1450
1.16
1.09
1.3
1.3
35.5
32.0
iu/l
0.53
141
1247
20
128
1.57
1.08
1.3
1.2
—
—
—
0
0
77
623
1.24
1.06
1.6
1.8
43.3
38.8
nmol/l
0.68
77
610
239
2133
1.13
1.06
1.7
1.7
—
—
—
0
0
6
122
0.49
1.05
1.0
1.0
269.7
305.7
ng/l
—
6
86
5
22
2.28
1.03
1.0
1.0
—
—
—
0
0
13
76
1.71
0.99
3.4
1.9
10.7
9.7
mmol/l
—
8
60
23
156
1.48
0.98
1.1
1.1
—
—
—
0
0
134
1547
0.86
0.96
1.8
1.7
—
—
—
0
0
33
241
1.37
0.96
1.4
1.3
—
—
—
0
0
12
69
1.74
0.96
2.0
3.0
—
—
—
0
0
0
32
0.00
0.95
0.0
3.4
—
42.5
—
0
25
7
37
1.89
0.94
2.7
1.2
—
—
—
0
0
7
37
1.89
0.94
2.3
2.5
—
—
—
0
0
6
119
0.50
0.93
1.2
1.1
—
—
—
0
0
185
1640
1.14
0.93
1.2
1.2
104.1
151.9
iu/ml
1.16
71
646
54
427
1.27
0.93
1.1
1.1
—
—
—
0
0
9
52
1.73
0.92
1.2
1.5
—
—
—
0
0
54
428
1.27
0.91
1.1
1.1
—
—
—
0
0
35
262
1.34
0.89
1.9
1.6
—
—
—
0
0
6
29
2.07
0.89
21.7
10.2
0.4
0.4
umol/l
—
6
29
55
439
1.26
0.89
1.7
1.3
—
—
—
0
0
8
42
1.91
0.88
1.5
2.1
—
—
—
0
0
8
44
1.82
0.85
1.5
1.8
—
—
—
0
0
6
31
1.94
0.84
2.0
2.6
—
11.7
—
0
5
86
727
1.19
0.82
1.8
1.9
—
—
—
0
0
15
97
1.55
0.81
1.6
1.9
—
—
—
0
0
21
294
0.71
0.80
1.3
1.2
—
—
—
0
0
6
33
1.82
0.79
3.8
2.5
—
—
—
0
0
11
66
1.67
0.78
1.5
1.3
—
—
—
0
0
0
26
0.00
0.78
0.0
5.1
—
—
—
0
0
43
340
1.27
0.77
3.6
2.9
—
—
—
0
0
106
919
1.16
0.76
2.0
1.8
—
—
—
0
0
2039
20095
1.08
0.76
16.2
12.5
40.3
40.3
%
0.06
1588
15705
901
8668
1.06
0.75
2.7
2.6
—
—
—
0
0
9
55
1.64
0.73
1.0
1.3
—
—
—
0
0
5
25
2.00
0.72
2.4
1.9
—
—
—
0
0
19
134
1.42
0.71
1.4
1.4
1661.3
2029.8
ml
—
6
28
22
160
1.38
0.70
1.6
1.2
—
—
—
0
0
7
41
1.71
0.70
1.4
1.1
—
—
—
0
0
69
583
1.19
0.69
2.4
3.4
0.2
0.3
g/l
0.76
38
242
14
93
1.51
0.69
1.6
3.2
74.0
177.1
umol/l
—
6
49
1914
18845
1.06
0.68
18.9
14.7
332.7
332.8
g/l
0.19
1900
18727
15
102
1.47
0.67
1.9
1.9
1.5
3.3
u/field
—
10
79
2057
20306
1.07
0.66
4.2
4.0
5.8
5.8
mmol/l
0.11
1941
18881
77
662
1.17
0.64
8.1
7.6
—
—
—
0
0
55
459
1.20
0.64
1.9
2.1
39.3
38.4
g/l
0.59
50
407
5
29
1.73
0.64
1.8
2.0
—
—
—
0
0
8
50
1.60
0.61
1.4
1.2
—
—
—
0
0
13
88
1.48
0.60
1.1
1.1
—
—
—
0
0
14
198
0.71
0.60
2.4
2.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
86
753
1.15
0.58
3.4
3.4
—
—
—
0
0
93
822
1.14
0.56
1.4
1.3
241.5
221.2
miu/ml
0.17
37
410
8
55
1.46
0.56
6.3
12.2
—
—
—
0
0
8
55
1.46
0.56
1.6
1.2
—
—
—
0
0
8
55
1.46
0.56
1.6
1.4
—
—
—
0
0
6
37
1.62
0.55
1.3
1.1
—
—
—
0
0
6
37
1.62
0.55
1.3
2.8
—
—
—
0
0
152
1386
1.10
0.54
2.1
2.3
12.3
12.7
nmol/l
0.22
139
1260
37
448
0.82
0.53
1.4
1.5
—
—
—
0
0
36
437
0.82
0.53
1.4
1.4
—
—
—
0
0
11
74
1.49
0.53
1.1
1.2
—
—
—
0
0
31
250
1.24
0.52
1.7
1.5
—
—
—
0
0
42
351
1.20
0.51
1.0
1.1
2.2
3.6
u/ml
0.72
22
178
30
367
0.82
0.49
1.1
1.1
198.8
26850.6
iu/ml
—
9
87
17
128
1.33
0.47
1.1
1.2
—
—
—
0
0
49
421
1.17
0.46
1.1
1.1
6.7
5.8
u/ml
0.13
27
205
180
1672
1.08
0.45
1.4
1.4
—
—
—
0
0
5
83
0.60
0.45
1.0
1.0
—
3.5
—
0
11
27
219
1.24
0.45
1.7
1.7
47.0
59.6
%
0.54
13
136
43
367
1.17
0.44
1.6
1.8
—
—
—
0
0
50
433
1.16
0.43
1.4
1.4
30.0
28.6
u/l
0.11
42
351
31
258
1.20
0.42
1.5
1.4
268.6
293.4
pmol/l
0.27
26
205
5
33
1.52
0.41
3.0
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
37
434
0.85
0.41
1.4
1.4
—
—
—
0
0
63
558
1.13
0.41
2.5
3.0
—
—
—
0
0
5
34
1.47
0.40
1.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
0.3
—
0
9
158
1471
1.08
0.39
2.4
2.8
4.0
4.1
e9/l
0.32
127
1213
265
2790
0.94
0.38
1.3
1.4
—
—
—
0
0
17
133
1.28
0.38
1.4
1.3
—
—
—
0
0
19
151
1.26
0.38
16.2
3.5
11.9
11.1
%
0.41
19
151
5
37
1.35
0.37
1.4
1.6
—
—
—
0
0
13
169
0.77
0.37
2.8
3.5
—
—
—
0
0
9
70
1.29
0.36
1.4
1.8
—
—
—
0
0
288
2750
1.05
0.35
2.4
2.6
0.8
0.7
ug/l
0.33
154
1590
45
395
1.14
0.34
1.1
1.1
0.8
2.4
u/ml
1.69
16
94
37
320
1.16
0.34
1.1
1.1
2.7
4.8
u/ml
0.98
22
121
479
4632
1.04
0.34
4.0
4.0
2.9
2.1
ug/l
0.48
442
4217
6
44
1.36
0.34
2.8
1.3
64.2
61.0
%
—
6
37
72
652
1.11
0.34
3.6
3.5
25.1
24.8
mmol/l
0.48
67
611
16
127
1.26
0.33
1.3
1.2
—
—
—
0
0
26
219
1.19
0.33
1.9
1.4
—
—
—
0
0
25
210
1.19
0.32
2.8
1.6
—
—
—
0
0
70
636
1.10
0.32
1.3
1.4
12.8
10.8
u/l
0.57
55
520
10
132
0.76
0.32
1.5
1.5
8931.2
110149.7
e6/l
—
5
77
11
83
1.33
0.32
1.8
1.7
—
—
—
0
0
18
147
1.23
0.30
1.9
1.3
—
—
—
0
0
17
138
1.23
0.30
3.2
2.1
0.5
2.1
u/field
—
10
74
31
268
1.16
0.30
1.3
1.3
—
—
—
0
0
11
141
0.78
0.29
1.7
2.0
—
1.5
—
0
12
24
204
1.18
0.28
2.5
3.6
45.4
42.0
u/ml
0.04
24
204
15
121
1.24
0.28
1.6
1.6
6.4
7.7
ug/l
0.26
15
104
20
167
1.20
0.28
1.4
1.5
—
—
—
0
0
60
546
1.10
0.28
2.6
2.5
—
—
—
0
0
9
119
0.76
0.27
1.4
1.5
—
—
—
0
0
10
128
0.78
0.26
1.8
1.4
5.6
6.4
mmol/l
—
10
116
43
386
1.12
0.26
4.4
3.2
24.4
24.8
mg/l
0.03
33
232
45
406
1.11
0.25
1.1
1.1
1.5
1.2
u/ml
0.14
21
160
58
532
1.09
0.24
1.2
1.3
—
—
—
0
0
15
124
1.21
0.24
2.1
1.5
—
—
—
0
0
52
475
1.10
0.23
1.1
1.1
1.2
1.6
u/ml
0.20
28
182
17
143
1.19
0.23
1.0
1.0
0.3
1.9
u/ml
—
5
48
25
219
1.14
0.22
1.1
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
39
354
1.10
0.20
1.1
1.0
2.6
3.0
u/ml
0.08
20
127
531
5420
0.97
0.20
4.1
3.9
6.2
8.5
mg/mmol
0.88
341
3424
23
202
1.14
0.20
2.2
3.0
0.8
0.8
nmol/l
0.06
14
163
31
280
1.11
0.18
1.4
1.3
56.1
64.1
mmol/l
0.50
25
232
37
403
0.92
0.17
1.4
1.5
0.2
0.3
nmol/l
1.48
30
305
7
63
1.11
0.17
2.1
1.2
—
—
—
0
0
15
129
1.16
0.17
2.1
1.6
—
—
—
0
0
31
283
1.10
0.16
1.5
1.5
—
—
—
0
0
21
187
1.12
0.15
1.7
1.4
0.9
1.0
g/l
1.09
21
187
10
83
1.21
0.15
1.2
1.2
—
—
—
0
0
9
81
1.11
0.15
1.1
1.1
—
—
—
0
0
22
198
1.11
0.14
1.8
2.2
—
—
—
0
0
25
228
1.10
0.13
1.0
1.1
—
—
—
0
0
14
159
0.88
0.13
1.6
1.4
6.3
6.6
mmol/l
—
8
100
11
94
1.17
0.13
1.2
1.2
—
—
—
0
0
22
242
0.91
0.13
1.3
1.2
—
—
—
0
0
5
44
1.14
0.10
1.0
1.4
21.7
75.9
mu/l
—
5
36
12
106
1.13
0.09
1.2
1.3
130.9
131.1
nmol/l
0.01
12
106
513
5187
0.99
0.09
3.1
3.2
538.2
373.8
mg/l
0.27
316
3237
5
47
1.06
0.09
1.6
2.0
13.8
17.1
umol/l
—
5
47
10
87
1.15
0.09
1.6
2.9
—
18.9
—
0
6
11
97
1.13
0.09
3.1
1.8
1.7
2.0
umol/l
0.87
11
89
6
54
1.11
0.09
1.0
1.1
—
—
—
0
0
56
582
0.96
0.08
2.1
2.0
4.2
4.5
iu/l
0.10
26
223
7
64
1.09
0.08
2.4
1.9
—
—
—
0
0
34
358
0.95
0.08
1.4
1.6
—
—
—
0
0
6
73
0.82
0.07
1.8
1.4
—
—
—
0
0
2036
20314
1.01
0.07
3.9
3.7
1.4
1.3
mmol/l
1.09
1930
19035
9
84
1.07
0.07
1.0
1.0
—
—
—
0
0
18
167
1.08
0.06
1.2
1.4
18.0
61.2
pmol/l
—
8
59
30
285
1.05
0.06
1.1
1.0
1.0
0.4
u/ml
0.54
11
65
9
103
0.87
0.06
1.4
1.1
1704.8
1464.4
miu/ml
—
9
103
27
256
1.06
0.06
1.2
1.3
—
—
nmol/l
—
0
0
547
5432
1.01
0.06
1.7
1.6
1.5
1.4
mmol/l
0.63
466
4644
2146
21426
1.01
0.06
4.7
4.4
2.9
2.9
mmol/l
0.30
2035
20124
11
100
1.10
0.05
1.2
1.7
—
8.4
—
0
8
11
100
1.10
0.05
1.1
2.4
17.9
99.6
ug/l
0.51
11
87
247
2496
0.99
0.05
1.6
1.7
—
—
—
0
0
44
426
1.03
0.05
3.5
2.3
1.0
0.8
nmol/l
0.36
37
362
12
130
0.92
0.04
2.5
2.2
—
—
—
0
0
15
140
1.07
0.04
1.3
1.2
—
—
—
0
0
572
5740
1.00
0.02
3.1
3.1
7.7
7.8
mmol/l
0.44
498
4913
2107
21053
1.00
0.02
4.3
4.1
1.5
1.5
mmol/l
0.77
1998
19805
2116
21175
1.00
0.02
4.3
4.1
4.8
4.8
mmol/l
0.40
2023
19996
15
143
1.05
0.01
1.1
1.2
—
—
—
0
0
16
153
1.05
0.01
1.9
1.5
30.5
34.4
g/l
0.40
16
133
52
512
1.02
0.01
8.4
3.8
1.4
1.4
mg/l
0.12
47
476
19
197
0.96
0.01
1.0
1.1
—
—
—
0
0
11
105
1.05
0.00
2.4
3.9
—
—
—
0
0
15
145
1.03
0.00
1.5
2.3
—
—
—
0
0
41
415
0.99
0.00
1.8
1.6
—
—
—
0
0
18
184
0.98
0.00
1.6
2.2
15.7
19.2
nmol/l
1.88
18
176
113
1126
1.00
0.00
1.1
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
8
82
0.98
0.00
1.8
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
18.8
—
0
7
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
7
78
0.90
0.00
1.1
1.8
—
—
—
0
0
5
55
0.91
0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
7
77
0.91
0.00
6.4
5.0
—
—
—
0
0
6
64
0.94
0.00
2.5
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
41
410
1.00
0.00
2.2
2.4
118.0
114.5
ug/min
0.02
26
254
5
52
0.96
0.00
1.4
1.3
46.8
27.4
%
—
5
36
18
180
1.00
0.00
4.3
2.8
38.5
37.4
mg/l
0.01
12
130
0
7
0.00
0.00
0.0
1.1
—
118.1
—
0
7

Mortality – FinRegistry

Association

Association between endpoint I9_LYMPHADE and mortality.

Females

Parameter HR [95% CI] p-value
I9_LYMPHADE 1.61 [1.34, 1.93] < 0.001
Birth year 0.998 [0.99, 1.01] 0.571

During the follow-up period (1.1.1998 — 31.12.2019), 257 out of 3491 females with I9_LYMPHADE died.

Males

Parameter HR [95% CI] p-value
I9_LYMPHADE 1.931 [1.62, 2.3] < 0.001
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 298 out of 3230 males with I9_LYMPHADE died.

Mortality risk

Mortality risk for people of age

years, who have I9_LYMPHADE.

N-year risk Females Males
1 0.154% 0.251%
5 0.839% 1.932%
10 2.414% 5.144%
15 4.555% 10.168%
20 8.072% 16.551%

Relationships between endpoints

Index endpoint: I9_LYMPHADE – Nonspecific lymphadenitis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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