placenta praevia: Abnormal placentation in which the placenta implants in the lower segment of the uterus (the zone of dilation) and may cover part or all of the opening of the cervix. It is often associated with serious antepartum bleeding and premature labor.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1886 |
4. Check minimum number of eventsNone |
1886 |
5. Include endpointsNone |
1886 |
6. Filter based on genotype QC (FinnGen only) |
1886 |
Control definitions (FinnGen only)
- Control exclude
- O15_MATERN_CARE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- O30-O48
- Name in latin
- Placenta praevia
Similar endpoints
↥List of similar endpoints to
Placenta praevia
based on the number of shared cases.
Similar with more cases:
- Maternal care related to the fetus and amniotic cavity and possible delivery problems
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 13295 | 13295 | - |
| Only index persons | 13162 | 13162 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.38 | 0.38 | - |
| Only index persons | 0.48 | 0.48 | - |
| Median age at first event (years) | |||
| Whole population | - | 32.14 | - |
| Only index persons | - | 32.12 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1886 | 1886 | - |
| Unadjusted period prevalence (%) | 0.64 | 0.64 | - |
| Median age at first event (years) | 32.29 | 32.29 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1652
- Matched controls
- 16519
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
22.2
323.0
771
627
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
+∞
323.0
967
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
4522.8
323.0
368
*
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
+∞
323.0
696
*
O82.0
ICD-10 Finland
Delivery by elective caesarean section
39.4
295.3
377
123
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
21.6
294.2
450
281
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
7.1
256.6
798
1921
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
+∞
210.0
197
*
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
4.8
191.4
1009
4077
O32.1
ICD-10 Finland
Maternal care for breech presentation
691.3
191.0
185
*
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
7.8
170.7
440
737
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
12.0
164.2
319
324
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
1755.1
162.2
155
*
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
6.7
162.2
469
919
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
4.5
152.1
718
2430
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
4.4
139.7
655
2161
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
732.5
138.9
135
*
Z39.2
ICD-10 Finland
Routine postpartum follow-up
4.3
126.5
588
1889
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
+∞
124.6
118
*
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
644.3
122.9
120
*
6411A
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Haemorrhage from placenta praevia[PLACENTA PRAEVIA CUM HAEMORRHAGIA,HOITOJ ENNEN SYNN]
+∞
119.2
113
*
SPAT1379
SPAT
Health check-up of pregnant person
4.4
110.3
478
1406
O60
ICD-10 Finland
Preterm labour and delivery
17.7
108.9
175
110
WX320
NOMESCO Finland
Spinalanesthesy
4.4
108.9
474
1398
SPAT1197
SPAT
Extensive health check-up of expecting family
3.8
104.1
539
1848
W78
ICPC
Pregnancy
3.6
101.3
594
2247
SPAT1380
SPAT
Postpartum check-up
4.4
98.1
411
1153
6411B
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Haemorrhage from placenta praevia[PLACENTA PRAEVIA CUM HAEMORRHAGIA,SYNN PÄÄTT HOITOJ]
+∞
96.8
92
*
O48
ICD-10 Finland
Prolonged pregnancy
+∞
95.8
91
*
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
4.6
85.2
335
870
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.8
84.5
419
1349
ZXD05
NOMESCO Finland
Urgent procedure
3.0
83.4
674
3114
O20.0
ICD-10 Finland
Threatened abortion
8.9
81.3
181
224
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
8.3
80.3
188
253
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
4.1
77.8
340
971
O41.0
ICD-10 Finland
Oligohydramnios
761.6
74.8
73
*
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
+∞
74.5
71
*
XMA22
NOMESCO Finland
General examination of pregnant woman
4.6
72.8
281
708
SPAT1196
SPAT
Monitoring of normal pregnancy
4.0
67.6
304
881
WX306
NOMESCO Finland
Lumbar epidural anesthesy
4.2
67.0
286
790
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
6.7
65.5
176
288
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
+∞
62.9
60
*
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
3.1
62.4
416
1631
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
3.3
62.3
370
1336
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
3.0
60.3
418
1676
O30.0
ICD-10 Finland
Twin pregnancy
+∞
59.7
57
*
8811
FHL
Cesarean section
5.0
58.9
204
454
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
588.0
58.0
57
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.6
57.0
292
935
MAA00
NOMESCO Finland
Amniocentesis
13.0
56.6
102
83
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
+∞
54.5
52
*
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
534.5
52.8
52
*
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
11.4
52.6
101
94
6410A
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Placenta praevia without haemorrhage[PLACENTA PRAEVIA SINE HAEMORRH,HOITOJ ENNEN SYNN]
+∞
51.3
49
*
O80.0
ICD-10 Finland
Spontaneous vertex delivery
2.2
49.7
869
5574
W84
ICPC
Pregnancy high risk
5.6
48.4
149
288
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
5.6
48.4
148
284
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
2.5
47.0
452
2159
O40
ICD-10 Finland
Polyhydramnios
+∞
45.0
43
*
O46.8
ICD-10 Finland
Other antepartum haemorrhage
+∞
43.9
42
*
W92
ICPC
Compl labour/ delivery livebirth
7.8
43.0
102
138
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
3.9
41.1
181
503
O02.1
ICD-10 Finland
Missed abortion
3.3
40.9
226
754
6410B
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Placenta praevia without haemorrhage[PLACENTA PRAEVIA SINE HAEMORRHAGIA,SYNN PÄÄT HOITOJ]
+∞
40.8
39
*
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
+∞
38.7
37
*
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
+∞
38.7
37
*
WX307
NOMESCO Finland
Obstetric epidural analgesia
2.8
38.3
283
1147
O80.8
ICD-10 Finland
Other single spontaneous delivery
4.5
37.6
140
332
Z37.0
ICD-10 Finland
Single live birth
2.4
37.4
377
1812
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
+∞
36.6
35
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.9
36.6
812
5476
G03GA01
ATC
chorionic gonadotrophin; parenteral
3.3
36.5
197
645
O47.9
ICD-10 Finland
False labour, unspecified
18.7
36.4
56
31
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
+∞
35.5
34
*
MAB20
NOMESCO Finland
Failed external version
126.1
34.8
37
*
O99.80
ICD-10 Finland
The fear of childbirth
3.6
34.7
170
515
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.5
33.5
289
1273
O72.0
ICD-10 Finland
Third-stage haemorrhage
5.0
32.5
109
232
MAX99
NOMESCO Finland
Assistance to normal delivery
2.3
32.0
331
1599
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
+∞
31.3
30
*
W85
ICPC
Gestational diabetes
3.7
31.0
143
412
ZXE00
NOMESCO Finland
One hour or less
1.9
29.6
671
4442
N97.9
ICD-10 Finland
Female infertility, unspecified
2.6
29.0
242
1041
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
3.3
29.0
156
507
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
6.0
28.5
80
138
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
28.2
537
3327
G03GA06
ATC
follitropin beta; parenteral
3.7
28.0
128
366
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
3.7
27.1
126
365
SPAT1357
SPAT
Monitoring of problem during pregnancy
4.3
26.9
104
256
W90
ICPC
Uncompl labour/delivery livebirth
3.3
26.9
143
461
H01CA02
ATC
nafarelin; nasal
3.4
25.7
133
420
MA3AE
NOMESCO Finland
Combined first trimester screening
3.1
25.6
147
501
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
3.0
24.1
147
519
G03GA05
ATC
follitropin alfa; parenteral
3.1
23.8
135
455
MAB10
NOMESCO Finland
External version
88.1
23.7
26
*
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.9
23.6
150
547
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
10.0
23.1
46
47
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
23.0
22
*
O45.9
ICD-10 Finland
Premature separation of placenta, unspecified
+∞
23.0
22
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
5.8
22.9
66
118
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
13.7
22.8
39
29
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
2.0
22.5
341
1915
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
2.9
22.3
144
530
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
4.0
22.3
92
241
Z3232
NOMESCO Finland
Midwife
2.1
22.2
301
1614
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
12.9
22.2
39
31
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
4.8
22.0
75
163
G03DA04
ATC
progesterone; systemic, rectal, vaginal
3.4
21.9
112
350
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
6.7
21.4
55
85
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
3.1
21.3
122
414
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
4.5
21.3
77
178
SPAT1189
SPAT
Other ultrasound examination during pregnancy
3.5
21.1
102
305
MAC96
NOMESCO Finland
Other induction or advancement of labour
4.0
20.8
85
221
SPAT1200
SPAT
Guidance for breast-feeding and breast care
3.7
20.1
89
248
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
58.3
19.9
23
*
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
+∞
19.8
19
*
N97.8
ICD-10 Finland
Female infertility of other origin
3.4
19.8
100
310
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
19.8
564
3879
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
202.3
19.6
20
*
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
9.7
19.4
39
41
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
3.1
19.1
110
375
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
10.2
18.9
37
37
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
+∞
18.8
18
*
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
7.5
18.7
44
60
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
4.3
18.3
68
162
Z39.1
ICD-10 Finland
Care and examination of lactating mother
4.2
18.2
69
168
Z34
ICD-10 Finland
Supervision of normal pregnancy
2.5
18.2
150
637
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
11.6
18.0
33
29
N80.1
ICD-10 Finland
Endometriosis of ovary
2.6
18.0
137
557
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
3.0
17.9
107
372
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
9.7
17.9
36
38
H01CC01
ATC
ganirelix; parenteral
2.9
17.7
111
400
SPAT1263
SPAT
Sampling
1.6
17.7
646
4718
MBB10
NOMESCO Finland
Packing of delivered uterus
37.1
17.6
22
6
TLW10
NOMESCO Finland
Transfer of fresh embryo
3.5
17.1
80
234
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
4.4
16.9
61
142
Z30.2
ICD-10 Finland
Sterilization
1.9
16.8
254
1411
6418A
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Other antepartum haemorrhage[ALIA HAEMORRHAGIA IN GRAVIDITATE,HOITOJ ENNEN SYNN]
+∞
16.7
16
*
L02AE02
ATC
leuprorelin; implant, parenteral
3.8
16.6
72
198
SPAT1373
SPAT
Combined screening in early pregnancy
4.8
16.6
55
117
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.9
16.5
290
1700
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.5
16.5
130
538
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
4.2
16.5
63
155
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
7.1
16.1
39
56
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
6.3
16.0
42
68
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
4.9
16.0
52
109
ZXD00
NOMESCO Finland
Emergency procedure
3.8
15.6
67
183
MBA05
NOMESCO Finland
Curettage of uterus after abortion
5.3
15.3
46
88
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
3.4
15.3
76
234
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
4.2
15.2
58
143
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
4.7
15.0
50
108
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
3.2
14.9
79
255
O61.0
ICD-10 Finland
Failed medical induction of labour
7.1
14.9
36
52
TLW12
NOMESCO Finland
Insertion of frozen embryo
3.4
14.8
72
218
Z36.8
ICD-10 Finland
Other antenatal screening
3.4
14.8
72
219
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
3.2
14.6
77
248
6419A
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Unspecified antepartum haemorrhage[HAEMORRHAGIA NUD IN GRAVIDITATE,HOITOJ ENN SYNN NUD]
+∞
14.6
14
*
W29
ICPC
Pregnancy symptom/complaint other
3.2
14.5
75
239
J01DB01
ATC
cefalexin; oral
1.6
14.3
1317
11707
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
5.7
14.1
40
72
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
3.4
13.9
66
197
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
13.8
486
3462
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
4.3
13.8
50
118
O34.8
ICD-10 Finland
Maternal care for other abnormalities of pelvic organs
+∞
13.6
13
*
O43.2
ICD-10 Finland
Morbidly adherent placenta
+∞
13.6
13
*
6412B
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Premature separation of placenta[ABLATIO PLACENTAE ANTETEMPUS,SYNN PÄÄTT HOITOJAKSO]
+∞
13.6
13
*
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
11.0
13.5
25
23
O85
ICD-10 Finland
Puerperal sepsis
5.7
13.5
38
68
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
5.2
13.2
40
78
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
5.6
13.0
37
67
P01AB01
ATC
metronidazole; oral, rectal
1.5
12.9
680
5289
W03
ICPC
Antepartum bleeding
5.9
12.9
35
60
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
2.3
12.8
121
550
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.8
12.8
245
1469
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
2.1
12.8
151
758
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
5.5
12.7
37
69
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
12.7
596
4521
G03GA02
ATC
human menopausal gonadotrophin; parenteral
2.6
12.5
90
355
O45.8
ICD-10 Finland
Other premature separation of placenta
+∞
12.5
12
*
O36.4
ICD-10 Finland
Maternal care for intrauterine death
+∞
12.5
12
*
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
3.6
12.5
55
155
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
5.1
12.3
38
76
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
3.7
12.2
52
143
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.8
12.2
79
292
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
26.9
12.0
16
6
XLA10
NOMESCO Finland
NA
2.3
12.0
110
491
B01AB05
ATC
enoxaparin; parenteral
1.6
12.0
335
2240
L02AE01
ATC
buserelin; implant, nasal, parenteral
4.0
11.9
47
121
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
8.4
11.8
25
30
O81.4
ICD-10 Finland
Vacuum extractor delivery
1.9
11.6
167
909
O44
ICD-10 Finland
Placenta praevia
+∞
11.5
11
*
O43.8
ICD-10 Finland
Other placental disorders
+∞
11.5
11
*
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
+∞
11.5
11
*
N97.1
ICD-10 Finland
Female infertility of tubal origin
3.8
11.3
46
122
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
4.2
11.2
42
103
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
3.4
11.2
53
159
R2110
NOMESCO Finland
Giving the first information
2.0
11.2
144
751
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
3.0
11.0
61
206
N02BE01
ATC
paracetamol; systemic, rectal
1.5
11.0
1323
11974
PC7NT
NOMESCO Finland
Endovascular occlusion of uteral arteries to stop puerperal bleeding
43.6
10.9
13
*
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.0
10.9
141
736
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
28.2
10.7
14
5
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
5.0
10.7
33
67
G02CB01
ATC
bromocriptine; systemic
3.3
10.5
51
157
A02BC01
ATC
omeprazole; systemic
1.6
10.4
324
2221
N80.9
ICD-10 Finland
Endometriosis, unspecified
2.5
10.3
80
332
G03GB02
ATC
clomifene; oral
2.8
10.2
64
234
W27
ICPC
Fear of complications of pregnancy
4.5
10.1
34
76
J01DA01
ATC
[U] cefalexin; systemic
1.4
9.9
987
8508
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
3.3
9.7
48
150
SPAT1315
SPAT
Periodic health check-up of children and adolescents
2.5
9.7
76
317
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
5.9
9.7
26
45
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
4.8
9.7
31
66
Z39
ICD-10 Finland
Postpartum care and examination
3.9
9.5
38
100
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
100.6
9.4
10
*
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
+∞
9.4
9
*
MA2BG
NOMESCO Finland
Fetal examination with high intensity magnet
+∞
9.4
9
*
O32.0
ICD-10 Finland
Maternal care for unstable lie
+∞
9.4
9
*
6581A
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Premature rupture of membranes
+∞
9.4
9
*
MCA30
NOMESCO Finland
Supravaginal caesarean hysterectomy
+∞
9.4
9
*
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
4.9
9.3
29
60
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
4.9
9.3
29
60
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.2
9.3
34
83
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
9.2
572
4512
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
2.4
9.1
76
328
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
9.1
91
427
O23.1
ICD-10 Finland
Infections of bladder in pregnancy
11.5
9.1
16
14
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
3.4
8.9
42
127
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
24.1
8.9
12
5
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
3.5
8.9
40
117
C08CA05
ATC
nifedipine; systemic
2.6
8.9
62
244
OAA12
SPAT
NA
3.2
8.8
44
139
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.3
8.7
81
370
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
4.7
8.4
27
58
O69.4
ICD-10 Finland
Labour and delivery complicated by vasa praevia
+∞
8.3
8
*
O43.9
ICD-10 Finland
Placental disorder, unspecified
+∞
8.3
8
*
O35.2
ICD-10 Finland
Maternal care for (suspected) hereditary disease in fetus
+∞
8.3
8
*
A05AA02
ATC
ursodeoxycholic acid; oral
3.4
8.3
38
113
LAA06
NOMESCO Finland
Transvaginal puncture of ovarian cyst
4.2
8.3
30
73
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
2.8
8.3
50
181
MAE00
NOMESCO Finland
Outlet vacuum delivery
1.8
8.2
137
784
TLW00
NOMESCO Finland
Insemination
2.5
8.2
63
260
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.2
8.1
40
126
MCA00
NOMESCO Finland
Upper uterine segment caesarean section
33.5
8.1
10
*
OAA11
SPAT
NA
2.4
8.0
66
284
MBA04
NOMESCO Finland
Curettage of uterus after delivery
4.6
8.0
26
57
SGA01
NOMESCO Finland
Tooth opening as first aid
1.5
7.9
274
1914
O80.1
ICD-10 Finland
Spontaneous breech delivery
7.8
7.9
17
22
O47
ICD-10 Finland
False labour
5.4
7.8
22
41
N80.89
ICD-10 Finland
Endometriosis with other specified or multiple localization
4.3
7.7
27
64
J01CA08
ATC
pivmecillinam; oral
1.3
7.7
781
6627
O14.1
ICD-10 Finland
Severe pre-eclampsia
4.1
7.6
28
70
Z36.2
ICD-10 Finland
Other antenatal screening based on amniocentesis
10.1
7.5
14
14
Z2221
NOMESCO Finland
Medical doctor
1.4
7.5
445
3456
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
2.8
7.5
46
169
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
3.0
7.5
41
140
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
2.7
7.4
48
182
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.7
7.3
166
1043
O41.9
ICD-10 Finland
Disorder of amniotic fluid and membranes, unspecified
+∞
7.3
7
*
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
+∞
7.3
7
*
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
+∞
7.3
7
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.4
7.2
60
259
B02AA02
ATC
tranexamic acid; systemic
1.5
7.2
302
2196
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.0
7.2
93
489
WX600
NOMESCO Finland
Single shot through catheter
2.8
7.1
42
150
6523B
ICD-9 Finland
Malposition and malpresentation of foetus, Transverse or oblique presentation[SITUS TRANSVERSUS ET OBLIQUUS,SYNNYTYKSEN AIKANA]
20.1
7.1
10
5
SPAT1192
SPAT
Gynaecological examination
1.5
7.1
261
1844
SPAT1195
SPAT
Antenatal classes
2.1
7.1
79
391
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
7.1
303
2214
SPAT1316
SPAT
Extensive health check-up of children and adolescents
2.3
7.0
64
288
Z31.2
ICD-10 Finland
In vitrofertilization
3.7
7.0
28
76
WW500
NOMESCO Finland
Blood transfusion
2.6
7.0
46
177
6671A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained portions of placenta or membranes, without haemorrhage
6.3
6.9
17
27
SPAT1303
SPAT
Counselling and guidance related to growth and development
4.3
6.9
24
57
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
4.6
6.9
22
48
JAH01
NOMESCO Finland
Laparoscopy
1.9
6.9
93
498
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.7
6.9
127
752
ULC02
NOMESCO Finland
Hysteroscopy
1.9
6.9
96
518
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
2.4
6.8
55
235
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.6
6.8
170
1099
O21
ICD-10 Finland
Excessive vomiting in pregnancy
4.5
6.8
22
49
MAW96
NOMESCO Finland
Other operation in pregnancy or at delivery
5.3
6.8
19
36
O34.4
ICD-10 Finland
Maternal care for other abnormalities of cervix
40.2
6.8
8
*
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
3.9
6.7
25
64
SPAT1382
SPAT
Extensive health check-up at 18 months of age
4.9
6.7
20
41
XMA20
NOMESCO Finland
Early examination of pregnancy
3.0
6.7
36
123
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
2.5
6.6
50
207
O70.2
ICD-10 Finland
Third degree perineal laceration during delivery
4.0
6.6
24
60
N83.1
ICD-10 Finland
Corpus luteum cyst
2.8
6.5
39
142
Z32
ICD-10 Finland
Pregnancy examination and test
3.5
6.5
28
81
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
3.3
6.5
30
92
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.3
6.5
478
3835
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
6.4
1509
14395
N05AH02
ATC
clozapine; systemic
0.1
6.4
*
191
W05
ICPC
Pregnancy vomiting/nausea
4.1
6.4
23
57
N99.4
ICD-10 Finland
Postprocedural pelvic peritoneal adhesions
4.0
6.3
23
58
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
3.7
6.3
25
68
O71.0
ICD-10 Finland
Rupture of uterus before onset of labour
+∞
6.3
6
*
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
3.2
6.2
30
96
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
2.0
6.1
72
365
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
2.7
6.1
40
153
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
6.1
941
8355
SPAT1383
SPAT
Extensive health check-up at 4 years of age
3.7
6.1
24
65
Mortality – FinRegistry
↥Association
Association between endpoint O15_PLAC_PRAEVIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_PLAC_PRAEVIA | 0.484 [0.36, 0.65] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.247 |
During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 10191 females with O15_PLAC_PRAEVIA died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_PLAC_PRAEVIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.045% | No data |
| 5 | 0.269% | No data |
| 10 | 0.725% | No data |
| 15 | 1.438% | No data |
| 20 | 2.38% | No data |
Relationships between endpoints
↥Index endpoint: O15_PLAC_PRAEVIA – Placenta praevia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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