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Primary angle-closure glaucoma


primary angle closure glaucoma: The sudden increase of intraocular pressure, resulting in pain and an abrupt decrease in visual acuity.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H40.2
Hospital discharge: ICD-9 3652
Hospital discharge: ICD-8 37500|37511
Cause of death: ICD-10 H40.2
Cause of death: ICD-9 3652
Cause of death: ICD-8 37500|37511

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Control exclude H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H40
Name in latin Glaucoma congestivum primarium

Summary Statistics

Key figures

All Female Male
Number of individuals 1307 761 546
Unadjusted prevalence (%) 0.32 0.33 0.30
Mean age at first event (years) 64.14 63.69 64.78


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 2.74 [2.02, 3.70] 5.6e-11 301
15 years 0.01 1.41 [1.03, 1.94] 3.1e-2 129
5 years 0.00 2.76 [2.09, 3.66] 1.1e-12 80
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: H7_GLAUCCLOSEPRIM – Primary angle-closure glaucoma
GWS hits:

Survival analyses between endpoints


before Primary angle-closure glaucoma
after Primary angle-closure glaucoma

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Drugs most likely to be purchased after Primary angle-closure glaucoma

Endpoint not on priority list, no data to show.