Melanocytic naevi, other sites/unspecified

CD2_BENIGN_MELANOCYTIC_NOS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D22.9&
  • Hospital discharge: ICD-9 216[8-9]A
  • Cause of death: ICD-10 D22.9&
  • Cause of death: ICD-9 216[8-9]A

2 out of 7 registries used, show all original rules.

3117

4. Check minimum number of events

None

3117

5. Include endpoints

None

3117

6. Filter based on genotype QC (FinnGen only)

3117

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus non specificatus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17921 10632 7232
Only index persons 17173 10310 6863
Unadjusted period prevalence (%)
Whole population 0.26 0.30 0.20
Only index persons 0.33 0.38 0.26
Median age at first event (years)
Whole population 46.63 44.10 50.35
Only index persons 46.96 44.28 50.98

-FinnGen-

Key figures

All Female Male
Number of individuals 3117 1925 1192
Unadjusted period prevalence (%) 0.61 0.66 0.53
Median age at first event (years) 53.48 48.97 60.76

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2774
Matched controls
27741
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.6
323.0
864
1139
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
5603.7
323.0
2739
430
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
11.4
323.0
759
890
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
9.6
267.9
591
757
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
7.4
232.6
613
1026
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
15.0
178.0
307
228
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
10.9
148.5
297
301
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
303.0
141.8
143
5
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
6.5
141.5
399
700
XQ845
NOMESCO Finland
Dermatoscopy
21.7
139.2
208
103
L57.0
ICD-10 Finland
Actinic keratosis
5.3
135.3
455
989
L82
ICD-10 Finland
Seborrhoeic keratosis
3.6
121.4
632
2076
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
31.6
120.2
161
54
XQ848
NOMESCO Finland
Dermatological photography
10.3
119.1
245
259
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
10.0
111.5
232
250
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
11.8
99.2
189
171
R23.8
ICD-10 Finland
Other and unspecified skin changes
3.1
94.6
606
2276
SPAT1153
SPAT
Removal of sutures
2.4
90.9
1038
5490
127
Kela drug reimbursment
Transplant complication
12.3
85.6
159
136
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
9.1
84.7
185
216
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
20.3
78.5
119
61
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.8
74.8
265
592
L04AA06
ATC
mycophenolic acid; systemic
10.2
73.9
151
156
Z94.0
ICD-10 Finland
Kidney transplant status
15.3
72.5
122
83
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
9.1
72.3
157
181
ZXC50
NOMESCO Finland
Cryotherapy
7.3
69.5
174
252
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
21.8
68.3
101
48
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
24.8
67.6
96
40
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
19.7
64.8
99
52
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
22.6
64.3
94
43
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
7.9
58.8
139
184
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
18.6
57.8
90
50
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
16.2
57.4
94
60
PJA12
NOMESCO Finland
Sentinel node biopsy
3.4
57.2
298
938
S18
ICPC
Laceration/cut
1.9
54.6
1174
7682
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
14.8
50.7
86
60
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
9.0
50.6
110
127
L04AD01
ATC
ciclosporin; systemic
7.0
48.6
124
184
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
7.1
48.5
123
181
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
3.8
48.0
216
601
S82
ICPC
Naevus/mole
2.5
45.9
406
1787
TQW99
NOMESCO Finland
Other minor procedure on skin
3.9
44.6
192
514
137
Kela drug reimbursment
Uraemia requiring dialysis
12.4
44.4
81
67
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
19.9
43.6
66
34
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.9
41.7
121
214
D03.5
ICD-10 Finland
Melanoma in situ of trunk
23.7
40.6
58
25
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
5.3
37.0
116
225
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
7.6
36.6
87
117
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
5.2
35.6
114
227
ZZR00
NOMESCO Finland
Flap of skin
5.9
35.4
102
179
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
15.0
35.4
59
40
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.1
34.9
204
693
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
4.9
34.7
117
247
TQW80
NOMESCO Finland
Local dermatologic skincare
4.6
34.5
125
284
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
5.1
34.1
111
225
C43.53
ICD-10 Finland
Malignant melanoma of the torso nodular
36.4
33.7
43
12
TK800
NOMESCO Finland
Hemodialysis
5.5
33.5
102
192
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
12.2
33.4
61
51
B05DA
ATC
Isotonic solutions
12.2
33.4
61
51
C43.79
ICD-10 Finland
Malignant melanoma of the lower extremity including hip or other unspecified histology
23.9
33.1
47
20
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
23.9
33.1
47
20
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
21.2
32.6
48
23
L04AA01
ATC
[U] ciclosporin; systemic
7.1
32.5
81
117
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
5.0
32.3
106
217
C43.51
ICD-10 Finland
Malignant melanoma of the trunk originating in lentigo maligna
43.9
31.9
39
9
8720/3-C44.7
ICD-O-3
Malignant melanoma, NOS, of skin of lower limb and hip
15.7
31.2
51
33
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
39.6
31.2
39
10
A12AA04
ATC
calcium carbonate; oral
6.1
30.6
85
143
D22
ICD-10 Finland
Melanocytic naevi
3.2
30.1
170
562
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
12.2
29.7
54
45
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
50.6
29.4
35
7
E0000UV
ATC
NA
1.6
29.4
1069
7762
L04AX01
ATC
azathioprine; systemic
3.2
28.5
156
506
B03XA02
ATC
darbepoetin alfa; parenteral
5.9
27.5
78
135
A11CC03
ATC
alfacalcidol; systemic
4.5
26.9
97
220
B07.9
ICD-10 Finland
Verruca simplex
3.5
26.5
127
373
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
9.3
26.4
55
60
8720/3-C44.6
ICD-O-3
Malignant melanoma, NOS, of skin of upper limb and shoulder
19.8
26.1
39
20
B05DB
ATC
Hypertonic solutions
11.1
25.8
49
45
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
8.1
25.6
58
73
ZXC15
NOMESCO Finland
Use of photodynamic technique
6.6
25.4
66
102
Z49.2
ICD-10 Finland
Other dialysis
9.4
25.2
52
56
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
6.1
25.1
69
115
SPAT1312
SPAT
General health counselling
1.6
25.1
879
6252
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
5.8
25.1
72
127
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
24.7
1032
7654
C44.81
ICD-10 Finland
Overall basocellular carcinoma of the skin
16.5
24.5
39
24
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
6.7
24.2
62
94
D23.9
ICD-10 Finland
Benign neoplasm: Skin, unspecified
4.3
24.1
92
222
2168A
ICD-9 Finland
Benign neoplasm of skin, Other specified sites of skin[IHON BEN KASV MUUALLA,NAEVUS PIGMENTOSUS]
+∞
24.0
23
*
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
17.8
23.9
37
21
QAA50
NOMESCO Finland
Cryotherapy of skin of head or neck
11.1
23.9
45
41
SAB01
NOMESCO Finland
Restricted oral and dental health check by dental hygienist or dental assistant
2.2
23.6
266
1295
C43.60
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder without histology
18.6
23.0
35
19
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.4
22.9
200
863
C43.69
ICD-10 Finland
Malignant melanoma of the upper extremity including shoulder other or unspecified histology
21.6
22.1
32
15
D23.3
ICD-10 Finland
Benign neoplasm: Skin of other and unspecified parts of face
3.8
21.4
93
253
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
6.5
20.8
54
84
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
8.9
20.8
44
50
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
5.8
20.5
58
101
QAE00
NOMESCO Finland
Excision of loose skin or fold of skin from head and neck
14.3
20.3
34
24
D22.4
ICD-10 Finland
Melanocytic naevi of scalp and neck
4.4
20.1
74
173
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
10.4
20.1
39
38
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
9.2
19.8
41
45
C43.99
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin other or unspecified histology
16.5
19.6
31
19
H02AB04
ATC
methylprednisolone; systemic
1.8
19.6
367
2168
C43.5
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of trunk
15.7
19.2
31
20
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
19.2
714
5089
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.7
19.1
133
506
SPAT1141
SPAT
Excision of skin or mucous membrane lesion
2.6
19.0
138
539
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
19.0
848
6292
V03AE02
ATC
sevelamer; oral
10.7
18.9
36
34
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
18.8
345
2020
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
16.3
18.3
29
18
C43
ICD-10 Finland
Malignant melanoma of skin
17.7
18.2
28
16
Q82.58
ICD-10 Finland
Congenital non-neoplastic naevus
6.7
18.1
46
70
N18.8
ICD-10 Finland
Other chronic renal failure
3.5
18.0
85
248
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
18.0
456
2940
SPAT1325
SPAT
Vaccination
1.5
17.9
801
5931
R4180
NOMESCO Finland
Podiatric therapy
7.0
17.9
44
64
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
26.9
17.8
24
9
8743/3-C44.5
ICD-O-3
Low cumulative sun damage melanoma of skin of trunk
22.9
17.7
25
11
C43.82
ICD-10 Finland
Overall malignant melanoma of the skin: 'superficial spreading' type
+∞
17.7
17
*
QXA50
NOMESCO Finland
Skin cryotherapy, unspecified location
7.5
17.6
41
55
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.1
17.6
55
109
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.4
17.6
154
667
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
2.9
17.3
106
373
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
3.8
17.0
73
198
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.2
16.9
89
283
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
5.6
16.9
49
89
C43.39
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face other or unspecified histology
19.4
16.9
25
13
C43.32
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face 'superficial spreading' type
63.7
16.7
19
*
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
8.5
16.7
36
43
180
Kela drug reimbursment
Interferon alfa
12.7
16.6
29
23
D06BB10
ATC
imiquimod; topical
2.4
16.6
139
589
C43.00
ICD-10 Finland
Malignant melanoma of the lip without histology
90.6
16.6
18
*
J01DB01
ATC
cefalexin; oral
1.5
16.5
2153
19447
Z94.1
ICD-10 Finland
Heart transplant status
18.0
16.4
25
14
TK820
NOMESCO Finland
Peritoneal dialysis
10.8
16.4
31
29
UJF32
NOMESCO Finland
Coloscopy
1.5
16.4
593
4174
QCE99
NOMESCO Finland
Other excision or repair of lesion of skin of upper limb
9.0
16.4
34
38
SPAT1301
SPAT
No procedures
1.5
16.3
759
5647
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
16.2
402
2570
N02BE01
ATC
paracetamol; systemic, rectal
1.5
16.1
2212
20124
D22.0
ICD-10 Finland
Melanocytic naevi of lip
16.8
16.1
25
15
1509
Kela drug reimbursment
Dabrafenib (adjuvant treatment)
47.8
16.0
19
*
3024
Kela drug reimbursment
Dabrafenib and trametinib (adjuvant treatment)
47.8
16.0
19
*
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
13.0
15.6
27
21
QBE00
NOMESCO Finland
Excision of loose skin or fold of skin from trunk
7.6
15.6
36
48
196
Kela drug reimbursment
Paricalcitol and cinacalcet
9.0
15.4
32
36
B03XA01
ATC
erythropoietin; parenteral
6.6
15.4
39
60
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
20.1
15.1
22
11
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
11.3
14.8
27
24
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
5.6
14.6
42
76
205
Kela drug reimbursment
Chronic hypertension
1.5
14.6
537
3781
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
4.5
14.6
51
115
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
14.5
517
3619
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
8.9
14.4
30
34
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
14.3
142
652
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
14.1
310
1913
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
8.0
14.0
31
39
C03CA01
ATC
furosemide; systemic
1.5
13.9
516
3634
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
2.1
13.9
166
829
C43.6
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of upper limb, including shoulder
30.2
13.9
18
6
C43.7
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of lower limb, including hip
17.6
13.8
21
12
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.3
13.7
50
118
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.5
13.7
645
4781
C02AC05
ATC
moxonidine; oral
2.5
13.6
110
458
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
13.5
992
7974
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
7.5
13.4
31
42
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
13.3
715
5429
C43.63
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder nodular
21.2
13.3
19
9
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
7.0
13.3
32
46
C08CA02
ATC
felodipine; oral
1.9
13.3
190
1018
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
13.3
247
1448
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
5.6
13.3
38
69
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.1
13.1
148
722
Z31.5
ICD-10 Finland
Genetic counselling
2.2
13.0
138
656
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
16.8
13.0
20
12
S77
ICPC
Malignant neoplasm of skin
4.8
13.0
42
88
9733
FHL
Excision of skin change in operating room or anesthesia
4.1
12.9
49
120
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.8
12.9
220
1254
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
12.8
973
7847
N18.0
ICD-10 Finland
End-stage renal disease
4.6
12.8
43
94
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
7.2
12.7
30
42
SPAT1263
SPAT
Sampling
1.4
12.7
1040
8492
ZZA00
NOMESCO Finland
Split skin graft
2.9
12.6
75
262
L01EC02
ATC
dabrafenib; oral
70.2
12.6
14
*
D23.6
ICD-10 Finland
Benign neoplasm: Skin of upper limb, including shoulder
5.1
12.6
39
78
167
Kela drug reimbursment
Dabrafenib, trametinib and vemurafenib
32.2
12.6
16
5
8720/3-C44.4
ICD-O-3
Malignant melanoma, NOS, of skin of scalp and neck
32.2
12.6
16
5
L91.0
ICD-10 Finland
Hypertrophic scar
3.9
12.5
50
129
V03AE01
ATC
polystyrene sulfonate; oral
4.9
12.5
40
83
C08CA13
ATC
lercanidipine; oral
1.7
12.5
268
1642
-
ICD-10 Finland
NA
3.0
12.4
71
240
QBA50
NOMESCO Finland
Cryotherapy of skin of trunk
11.7
12.3
22
19
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
10.5
12.2
23
22
C43.49
ICD-10 Finland
Malignant melanoma of the scalp and neck other or unspecified histology
15.9
12.1
19
12
PJ5AQ
NOMESCO Finland
Sentinell lymphnode SPECT with low dose CT
8.7
12.0
25
29
QXA05
NOMESCO Finland
Skin division, unspecified location
9.3
12.0
24
26
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
11.9
279
1750
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
13.4
11.9
20
15
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
11.7
525
3837
L04AA05
ATC
[U] tacrolimus; systemic
30.1
11.6
15
5
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
30.1
11.6
15
5
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
3.3
11.5
58
181
2169A
ICD-9 Finland
Benign neoplasm of skin, Skin, site unspecified[IHON BEN KASV,NUD,NAEVUS PIGMENTOSUS]
+∞
11.5
11
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
4.7
11.3
37
79
JAL10
NOMESCO Finland
Laparotomy and removal of foreign body
35.2
11.3
14
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.2
11.2
116
545
C44.52
ICD-10 Finland
Spinocellular carcinoma of the skin on the torso
9.6
11.2
22
23
SPAT1260
SPAT
Consultation of another employee
1.5
11.2
410
2874
L01XE23
ATC
[U] dabrafenib; oral
25.1
11.1
15
6
C43.73
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip nodular
12.7
11.1
19
15
C43.71
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip originating in lentigo maligna
20.1
11.1
16
8
C02CA01
ATC
prazosin; oral
4.1
11.1
42
104
A98
ICPC
Health maint/preventive medicine
1.8
11.1
2636
25381
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.9
11.0
170
940
J01MA02
ATC
ciprofloxacin; systemic
1.3
10.9
858
6914
S15
ICPC
Foreign body in skin
2.0
10.9
145
758
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
4.1
10.8
41
102
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
10.8
131
659
S29
ICPC
Skin symptom/complaint other
1.5
10.7
374
2591
L01EE01
ATC
trametinib; oral
60.2
10.6
12
*
SPAT1324
SPAT
Screening procedure
1.4
10.6
471
3434
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
10.6
618
4736
C44.50
ICD-10 Finland
Malignant tumor of the skin on the torso without histology
11.2
10.5
19
17
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
10.5
1260
10788
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
10.3
186
1081
R01AD09
ATC
mometasone; nasal
1.3
10.3
1103
9291
V03AE03
ATC
lanthanum carbonate; oral
8.8
10.3
21
24
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
10.2
862
7008
H02AB09
ATC
hydrocortisone; systemic
2.9
10.2
61
216
J01FA10
ATC
azithromycin; systemic
1.3
10.2
1473
12922
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
6.2
10.1
26
42
CBB30
NOMESCO Finland
Excision of lesion of eyelid
2.6
10.1
73
289
QXE99
NOMESCO Finland
Other excision or repair of unspecified region of skin
14.6
10.0
16
11
D06BX01
ATC
metronidazole; topical
1.6
10.0
247
1574
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
5.1
10.0
30
59
SDA02
NOMESCO Finland
Parodonthologic therapy
1.3
9.9
783
6293
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
9.8
267
1742
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
9.8
178
1037
R50.9
ICD-10 Finland
Fever, unspecified
1.5
9.8
311
2107
C43.40
ICD-10 Finland
Malignant melanoma of the scalp and neck without histology
26.1
9.8
13
5
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
3.3
9.8
47
143
TFJ02
NOMESCO Finland
Muscle biopsy of heart
9.6
9.7
19
20
ZXA00
NOMESCO Finland
Right side
1.4
9.7
569
4353
ZXA05
NOMESCO Finland
Left side
1.4
9.7
534
4042
D07AC01
ATC
betamethasone; topical
1.3
9.4
777
6279
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
9.4
833
6801
362
Kela drug reimbursment
Dabrafenib, trametinib and vemurafenib
30.1
9.4
12
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.2
9.4
91
419
C43.42
ICD-10 Finland
Malignant melanoma of the scalp and neck: 'superficial spreading' type
21.8
9.3
13
6
8097/3-C44.9
ICD-O-3
Basal cell carcinoma, nodular of skin, NOS
4.7
9.3
30
64
A02BC05
ATC
esomeprazole; systemic
1.3
9.3
906
7502
ZZA50
NOMESCO Finland
Full thickness skin graft
6.4
9.2
23
36
D02AE01
ATC
carbamide; topical
1.8
9.2
162
936
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.6
9.2
64
249
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
2.4
9.2
73
304
C43.30
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face without histology
13.7
9.2
15
11
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.8
9.2
158
908
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
1.5
9.2
282
1898
C07AB02
ATC
metoprolol; systemic
1.5
9.1
382
2745
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
9.1
945
7881
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
9.1
609
4762
J01CA04
ATC
amoxicillin; systemic
1.3
9.1
2093
19397
8090/3-C44.6
ICD-O-3
Basal cell carcinoma, NOS, of skin of upper limb and shoulder
6.3
9.1
23
37
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
5.1
9.1
27
53
Z49.0
ICD-10 Finland
Preparatory care for dialysis
4.2
9.0
33
80
A02BC02
ATC
pantoprazole; systemic
1.3
9.0
1516
13467
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
9.0
276
1856
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
18.6
8.9
13
7
C43.90
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin without histology
24.1
8.9
12
5
J05AB01
ATC
aciclovir; systemic
1.4
8.9
473
3556
D01AE16
ATC
amorolfine; topical
1.6
8.8
240
1568
QBA10
NOMESCO Finland
Incision of skin of trunk
3.5
8.8
39
112
C44.42
ICD-10 Finland
Spinocellular carcinoma of the skin of the scalp and neck
8.6
8.8
18
21
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
8.7
641
5083
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.4
8.7
386
2805
FQA00
NOMESCO Finland
Orthotopic transplantation of heart
50.1
8.7
10
*
321
Kela drug reimbursment
Paricalcitol and cinacalcet
6.6
8.6
21
32
C44.39
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face other or unspecified histology
5.8
8.6
23
40
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
8.6
701
5646
4056
NOMESCO Finland
NA
16.3
8.5
13
8
C09CA01
ATC
losartan; oral
1.4
8.5
468
3536
A54
ICPC
General and Unspecified, Repair/fix-suture/cast/prosth device
3.0
8.5
46
154
L72.1
ICD-10 Finland
Trichilemmal cyst
1.8
8.5
141
801
L01XE25
ATC
[U] trametinib; oral
27.6
8.5
11
*
ZX120
NOMESCO Finland
Intravenous
1.6
8.5
203
1282
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.7
8.5
177
1076
8090/3-C44.4
ICD-O-3
Basal cell carcinoma, NOS, of skin of scalp and neck
6.0
8.4
22
37
L03AB05
ATC
interferon alfa-2b; parenteral
7.3
8.4
19
26
C43.89
ICD-10 Finland
Overall malignant melanoma of the skin other or unspecified histology
90.3
8.4
9
*
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
3.4
8.3
38
113
Z94.2
ICD-10 Finland
Lung transplant status
10.8
8.3
15
14
D22.2
ICD-10 Finland
Melanocytic naevi of ear and external auricular canal
10.8
8.3
15
14
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
8.3
493
3774
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
5.8
8.3
22
38
H05BX01
ATC
cinacalcet; oral
5.8
8.3
22
38
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.0
8.3
44
146
C44.72
ICD-10 Finland
Spinocellular carcinoma of the skin of the lower extremity including the hip
14.5
8.2
13
9
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
6.5
8.2
20
31
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
2.2
8.1
77
351
SPAT1310
SPAT
Counselling related to known health issue
1.3
8.1
728
5935
5AB14
NOMESCO Finland
NA
11.7
8.1
14
12
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
8.0
1631
14737
C03DA01
ATC
spironolactone; oral
1.6
7.9
201
1292
R22.7
ICD-10 Finland
Localized swelling, mass and lump, multiple sites
10.8
7.8
14
13
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.3
7.8
675
5472
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
3.5
7.8
34
98
D23.7
ICD-10 Finland
Benign neoplasm: Skin of lower limb, including hip
3.5
7.8
34
98
E000001
ATC
NA
1.4
7.7
470
3609
J02AC01
ATC
fluconazole; systemic
1.3
7.7
959
8149
Z80.9
ICD-10 Finland
Family history of malignant neoplasm, unspecified
45.1
7.7
9
*
PJD55
NOMESCO Finland
Block dissection of inguinal lymph nodes
15.0
7.7
12
8
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.5
7.7
55
220
602
Kela drug reimbursment
Children's severe malnutrition
11.9
7.6
13
11
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
11.9
7.6
13
11
L85.89
ICD-10 Finland
Other specified epidermal thickening
11.9
7.6
13
11
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
4.3
7.5
26
61
C08CA01
ATC
amlodipine; oral
1.3
7.5
668
5432
A02BC01
ATC
omeprazole; systemic
1.3
7.5
577
4595
C10AA03
ATC
pravastatin; oral
1.8
7.5
132
765
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
3.2
7.4
37
118
C43.80
ICD-10 Finland
Overall malignant melanoma of the skin without histology
80.3
7.4
8
*
C44.91
ICD-10 Finland
Unspecified localization of basocellular carcinoma of the skin
6.0
7.4
19
32
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
4.1
7.4
27
67
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.2
7.3
67
303
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.6
7.3
164
1021
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.3
958
8182
XJH00
NOMESCO Finland
Transanal ultrasonography
1.8
7.2
110
609
HA1AA
NOMESCO Finland
X-ray mammography
1.7
7.2
150
913
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
7.2
223
1506
C07AG02
ATC
carvedilol; oral
1.8
7.2
113
633
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.8
7.2
111
618
WB323
NOMESCO Finland
Demanding adjuvant therapy of malignancy with biomodifiers
30.1
7.1
9
*
C44.59
ICD-10 Finland
Malignant tumor of the skin on the trunk other or unspecified histology
20.1
7.1
10
5
D07AD01
ATC
clobetasol; topical
1.4
7.1
326
2381
8090/3-C44.2
ICD-O-3
Basal cell carcinoma, NOS, of external ear
7.9
7.1
15
19
B35.3
ICD-10 Finland
Tinea pedis
2.0
7.1
86
437
7151
FHL
Kidney transplantation
12.0
7.1
12
10
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.1
300
2161
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
7.1
1768
16226
QDH05
NOMESCO Finland
Correction of deformity of toe nail
8.8
7.0
14
16
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
8.8
7.0
14
16
ZX108
NOMESCO Finland
Inhalation
4.3
7.0
24
56
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
1.8
7.0
110
616
L84
ICD-10 Finland
Corns and callosities
2.1
7.0
74
355
QAE20
NOMESCO Finland
Excision and repair of scar or web of skin of head or neck
7.0
7.0
16
23
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.5
7.0
225
1532
C09AA02
ATC
enalapril; systemic
1.4
6.9
359
2684
8090/3-C44.1
ICD-O-3
Basal cell carcinoma, NOS, of eyelid
5.8
6.9
18
31
XKD00
NOMESCO Finland
Uroflowmetry
1.4
6.9
291
2092
J05AB11
ATC
valaciclovir; oral
1.4
6.9
279
1993
J01DA01
ATC
[U] cefalexin; systemic
1.2
6.8
1508
13621
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
2.0
6.8
80
402
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
4.8
6.8
21
44
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
2.7
6.8
42
156
D03.4
ICD-10 Finland
Melanoma in situ of scalp and neck
40.1
6.8
8
*
C43.74
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip acral
40.1
6.8
8
*
D03.9
ICD-10 Finland
Melanoma in situ, unspecified
16.7
6.7
10
6
C43.61
ICD-10 Finland
Malignant melanoma of the upper extremity including the shoulder originating in lentigo maligna
16.7
6.7
10
6
C44.60
ICD-10 Finland
Malignant tumor of the skin of the upper extremity including the shoulder without histology
16.7
6.7
10
6
S21
ICPC
Skin texture symptom/complaint
1.5
6.7
253
1778
-54
ICPC
Repair/fix-suture/cast/prosth device
2.3
6.7
57
249
J35.0
ICD-10 Finland
Chronic tonsillitis
1.7
6.7
127
757
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
2.8
6.7
40
145
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
22.6
6.7
9
*
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
3.6
6.7
28
79
C02EA02
ATC
NA
2.0
6.7
77
387
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
3.0
6.7
35
117
L85.3
ICD-10 Finland
Xerosis cutis
3.8
6.7
26
69
D31.3
ICD-10 Finland
Benign neoplasm: Choroid
3.0
6.6
36
123
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.5
6.6
242
1692
B01AB05
ATC
enoxaparin; parenteral
1.3
6.6
615
5018
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
2.7
6.6
43
163
C43.9
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of skin, unspecified
12.3
6.6
11
9
S19
ICPC
Skin injury other
2.0
6.6
82
422
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.5
505
4017
R01AD12
ATC
fluticasone furoate; nasal
1.3
6.5
693
5748
DAB10
NOMESCO Finland
Partial excision of auricle
10.0
6.5
12
12
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
4.8
6.5
20
42
Z00.0
ICD-10 Finland
General medical examination
1.4
6.5
401
3085
N63
ICD-10 Finland
Unspecified lump in breast
1.7
6.5
133
808
C44.62
ICD-10 Finland
Spinocellular carcinoma of the skin of the upper extremity including the shoulder
6.2
6.5
16
26
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
6.5
233
1625
C43.92
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin: 'superficial spreading' type
70.0
6.4
7
*
D18.0
ICD-10 Finland
Haemangioma, any site
2.3
6.4
53
230
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
7.4
6.4
14
19
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
1.7
6.4
115
673
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
6.4
424
3300
S59
ICPC
Skin, Other therap proced/minor surg NEC
3.2
6.3
31
99
D06BX02
ATC
ingenol mebutate; topical
3.2
6.3
31
99
K50.8
ICD-10 Finland
Other Crohn disease
2.6
6.3
43
169
A12BA01
ATC
potassium chloride; oral
2.0
6.3
70
347
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
4.6
6.3
20
44
VALMI
NOMESCO Finland
NA
1.3
6.3
576
4689
C44.90
ICD-10 Finland
Unspecified localization of malignant tumor of the skin without histology
18.0
6.3
9
5
QCA50
NOMESCO Finland
Cryotherapy of skin of upper limb
18.0
6.3
9
5
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
6.2
643
5313
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.4
6.2
281
2045
B35.1
ICD-10 Finland
Tinea unguium
1.7
6.2
121
726
ZQZ00
NOMESCO Finland
Treatment of several skin areas
4.8
6.2
19
40
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
7.0
6.2
14
20
JN4AD
NOMESCO Finland
Body CT examination
1.6
6.2
139
869
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
0.2
6.2
*
256
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.5
6.1
211
1459
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
1.8
6.1
93
517
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.8
6.1
89
489
C08CA05
ATC
nifedipine; systemic
1.7
6.1
116
693
R06AE07
ATC
cetirizine; oral
1.2
6.1
1013
8843
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.3
6.1
55
247
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
4.9
6.0
18
37
GDG10
NOMESCO Finland
Bilateral transplantation of lung
10.0
6.0
11
11
EMB10
NOMESCO Finland
Tonsillectomy
1.6
6.0
137
859
ZXA10
NOMESCO Finland
Bilateral
1.4
6.0
362
2771
P15
ICPC
Chronic alcohol abuse
0.2
6.0
7
309

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1860
10454
2.93
183.91
3.0
2.0
—
—
—
0
0
157
150
10.97
144.31
1.2
1.6
6.4
8.1
ug/l
0.57
151
128
105
56
19.37
133.90
1.0
1.9
1.8
1.8
ug/l
0.01
45
27
712
3256
2.54
93.55
1.7
1.3
—
—
—
0
0
105
110
9.84
90.16
45.6
34.9
7.0
7.5
ug/l
1.31
93
101
101
109
9.54
84.82
30.0
25.4
95.6
117.5
ug/l
2.12
84
90
993
5988
1.97
61.85
6.7
4.3
—
—
—
0
0
1887
14887
1.68
41.33
10.9
8.9
4.0
4.1
e9/l
0.98
1723
13041
1681
12885
1.66
41.05
8.0
5.9
0.5
0.6
e9/l
8.92
1534
11205
1683
12922
1.66
40.68
8.0
5.9
0.0
0.0
e9/l
0.17
1536
11240
1718
13296
1.65
39.93
8.0
5.9
1.9
1.9
e9/l
0.08
1591
11805
1718
13379
1.63
38.24
8.1
6.1
0.2
0.2
e9/l
3.20
1591
11829
994
6774
1.69
37.31
5.8
3.7
0.0
0.0
estimate
0.06
320
2368
838
5470
1.73
36.80
5.4
3.7
1.0
1.0
kg/l
1.32
87
787
382
1950
2.09
35.94
5.6
3.3
—
—
—
0
0
1389
10498
1.58
33.25
2.7
2.2
77.8
75.9
nmol/l
2.02
1296
9570
1616
12727
1.56
31.75
5.1
3.4
0.0
0.0
estimate
1.32
318
2365
2271
19351
1.64
31.75
10.3
7.3
73.9
76.7
u/l
2.20
2166
18286
1603
12602
1.56
31.75
6.4
4.6
0.0
0.0
estimate
0.50
326
2446
1597
12585
1.55
30.99
5.0
3.4
0.0
0.0
estimate
0.50
312
2388
1278
9729
1.53
28.10
4.7
3.2
—
5.8
—
0
7
1345
10352
1.53
28.10
6.8
4.8
36.4
35.9
g/l
3.18
1273
9655
507
3082
1.77
27.71
12.0
6.0
1.1
1.0
mmol/l
3.84
489
2875
379
2121
1.90
27.07
1.6
1.4
—
—
—
0
0
372
2071
1.90
26.99
17.6
7.7
10.9
9.3
mmol/l
4.12
367
1981
1496
11886
1.50
26.19
10.6
6.7
1.2
1.2
mmol/l
0.44
1263
10084
2851
26268
2.00
25.88
19.2
14.6
139.8
139.6
mmol/l
2.33
2798
25621
49
91
5.45
25.24
2.1
1.7
—
—
—
0
0
1588
12838
1.48
25.08
7.6
6.1
10.7
11.1
umol/l
0.85
1522
12174
318
1737
1.93
24.34
6.8
3.9
124.4
85.1
ng/l
4.90
286
1536
2850
26358
1.95
24.02
19.4
14.7
4.0
4.0
mmol/l
0.05
2792
25670
239
1190
2.09
23.74
4.4
2.8
0.2
0.3
e6/l
0.23
233
1152
2820
26066
1.86
22.72
17.2
13.1
19.9
22.6
mg/l
4.53
2261
20472
321
1798
1.88
22.71
1.2
1.3
124.4
206.9
u/ml
1.75
301
1664
1426
11448
1.45
22.37
12.3
9.1
0.0
0.0
e9/l
1.31
1227
9364
44
83
5.36
22.30
6.2
4.9
—
—
—
0
0
212
1039
2.12
21.93
1.2
1.2
—
—
—
0
0
2468
22093
1.56
21.86
19.9
15.7
13.6
13.6
%
0.42
2437
21627
404
2460
1.74
21.60
3.3
2.1
365.0
372.4
nmol/l
0.35
381
2264
2918
27351
2.05
21.44
16.8
12.2
—
—
—
0
0
148
637
2.39
20.94
6.8
3.9
1.7
1.5
mg/l
2.06
140
589
355
2118
1.76
20.33
5.5
4.2
1.0
0.9
%
0.31
96
576
2929
27567
2.04
20.07
20.6
14.8
81.7
75.0
umol/l
12.24
2929
27557
2940
27720
2.07
19.84
13.2
9.8
25.7
26.3
u/l
0.97
2872
26834
325
1907
1.79
19.69
5.7
4.3
0.1
0.4
%
0.86
76
456
338
2017
1.76
19.31
5.6
4.2
0.1
0.1
%
0.02
87
532
2159
18986
1.45
19.15
5.1
3.9
11.0
11.2
mm/h
0.33
2027
17673
710
5099
1.51
18.98
3.9
2.5
4.5
6.4
e6/l
3.90
648
4476
116
470
2.52
18.72
1.5
1.4
26.2
25.9
u/l
0.04
98
390
2287
20366
1.46
18.69
4.8
4.0
14.8
14.6
pmol/l
4.44
2135
18745
1014
7828
1.44
18.66
3.8
2.6
58.2
57.1
u/l
0.36
951
7252
454
2972
1.62
18.24
2.0
1.7
—
—
—
0
0
108
431
2.56
18.00
6.1
3.0
—
—
—
0
0
2004
17491
1.41
17.75
4.3
3.5
—
—
—
0
0
1468
12179
1.39
17.50
4.2
4.0
—
—
—
0
0
1128
8976
1.40
17.14
3.9
3.4
45.3
50.8
ng/l
0.23
751
5629
779
5807
1.46
17.00
5.2
3.4
—
—
—
0
0
2611
24029
1.53
16.78
5.6
4.7
1.9
2.0
mu/l
0.87
2472
22296
912
7018
1.42
16.69
7.5
3.9
7.4
7.4
ph
1.37
194
1345
317
1946
1.70
16.28
5.0
4.0
0.6
0.6
%
0.04
65
429
3037
29202
2.56
16.27
25.7
19.1
251.6
254.6
e9/l
1.73
3001
28530
3038
29219
2.57
16.21
25.6
19.0
30.2
30.2
pg
0.00
3017
28856
3038
29219
2.57
16.21
25.6
19.1
90.7
90.7
fl
0.06
3017
28859
3038
29225
2.56
16.09
25.7
19.1
4.5
4.5
e12/l
0.03
2991
28485
3038
29229
2.55
16.01
25.8
19.2
6.6
6.7
e9/l
1.53
2989
28484
3038
29234
2.55
15.91
25.8
19.2
135.8
135.7
g/l
0.17
3018
28868
924
7175
1.41
15.91
2.4
2.1
145.6
208.8
u/l
2.93
878
6784
1305
10744
1.37
15.73
9.3
6.0
1.2
1.2
mmol/l
0.93
1207
9772
847
6502
1.42
15.50
3.6
2.6
4358.6
4334.3
umol/l
0.01
760
5691
548
3889
1.50
15.14
5.4
3.5
0.8
0.8
mmol/l
0.77
522
3661
1687
14525
1.35
14.91
5.9
4.8
6.5
6.6
mmol/l
0.99
1582
13484
1904
16758
1.35
14.23
5.0
4.2
292.9
1413.0
e6/l
1.90
30
221
640
4737
1.44
14.15
4.6
2.7
527.6
550.8
mosm/kgh2o
1.92
578
4045
80
313
2.60
13.95
1.6
1.5
—
—
—
0
0
859
6716
1.39
13.84
4.3
3.0
0.3
0.4
e6/l
2.13
715
5046
117
552
2.16
13.40
4.2
4.2
—
—
—
0
0
253
1544
1.70
13.24
1.4
1.2
—
—
—
0
0
277
1744
1.65
12.87
5.6
3.2
4.9
4.6
kpa
1.08
270
1682
166
902
1.89
12.86
6.5
4.8
—
—
—
0
0
470
3345
1.48
12.63
2.8
2.4
127.0
123.4
ug/g
0.07
393
2657
2650
24787
1.46
12.52
5.1
4.2
5.8
5.9
mmol/l
1.58
2474
22844
182
1033
1.81
12.28
4.6
2.8
0.7
0.7
%
0.02
176
995
881
7034
1.35
12.14
4.2
3.1
—
—
—
0
0
894
7156
1.35
12.11
3.3
2.9
—
—
—
0
0
2715
25565
1.48
11.89
4.9
4.1
4.6
4.7
mmol/l
3.45
2579
23969
416
2927
1.49
11.80
7.6
7.3
104.4
104.4
mmol/l
0.04
410
2857
1972
17671
1.32
11.76
5.2
4.1
—
—
—
0
0
2744
25946
1.48
11.22
5.3
4.5
2.7
2.8
mmol/l
3.57
2576
24170
778
6165
1.35
11.10
3.7
3.0
1457.0
1237.4
ng/l
0.64
679
5214
828
6629
1.34
11.02
4.0
3.0
—
—
—
0
0
1056
8757
1.31
10.96
5.2
3.6
90.5
96.9
e6/l
0.07
848
6086
509
3771
1.42
10.94
4.3
2.4
13.8
13.5
umol/l
0.48
486
3496
2612
24500
1.41
10.91
4.5
3.7
1.3
1.3
mmol/l
0.96
2445
22739
317
2141
1.54
10.91
6.3
3.9
5.8
5.9
kpa
0.16
310
2074
105
517
2.07
10.83
3.9
3.8
56.4
57.4
%
0.41
105
517
1388
11971
1.29
10.58
3.7
2.8
116.6
111.6
ug/l
0.34
1317
11181
471
3464
1.42
10.52
4.4
2.4
2.3
2.4
g/l
0.44
455
3220
442
3215
1.44
10.49
4.6
2.5
24.1
23.4
%
0.51
389
2758
313
2126
1.52
10.49
6.4
3.9
1.7
2.0
mmol/l
0.68
259
1709
289
1931
1.55
10.44
6.6
3.6
1.2
1.2
mmol/l
0.05
258
1682
73
315
2.35
10.42
1.2
1.2
—
—
—
0
0
417
3005
1.45
10.40
1.8
1.4
—
—
—
0
0
31
83
3.76
10.30
3.4
2.6
—
—
—
0
0
104
521
2.03
10.26
2.1
1.4
103.3
116.6
u/ml
0.62
26
101
539
4077
1.39
10.22
3.2
2.7
1.7
1.0
e6/l
0.42
369
2289
900
7357
1.31
10.21
4.9
3.1
35.0
86.5
e6/l
2.54
760
5630
76
338
2.28
10.13
2.4
2.4
—
—
—
0
0
49
178
2.78
9.96
3.7
2.3
773.9
633.3
ml
1.30
41
120
320
2208
1.50
9.94
6.4
3.9
—
7.4
—
0
12
983
8158
1.30
9.91
4.1
3.3
2.3
2.4
mmol/l
0.32
891
7222
2686
25424
1.41
9.69
4.9
4.1
1.5
1.5
mmol/l
0.69
2526
23699
1354
11733
1.27
9.62
8.2
6.0
0.7
0.7
%
0.06
1289
10991
1399
12173
1.27
9.60
8.4
6.3
8.4
8.5
%
0.12
1338
11453
1390
12104
1.27
9.41
8.2
6.0
2.8
2.8
%
0.16
1324
11314
1434
12568
1.26
9.08
8.2
6.0
28.7
28.4
%
0.30
1365
11780
2476
23200
1.33
9.03
6.4
5.2
39.1
39.2
mmol/mol
0.10
2335
21687
106
564
1.91
8.84
2.2
1.4
—
—
—
0
0
1112
9487
1.27
8.74
9.9
8.7
1.2
1.2
inr
1.14
359
2836
1409
12390
1.25
8.44
7.9
5.8
57.3
56.9
%
0.52
1346
11648
1013
8581
1.27
8.37
7.4
5.9
—
—
—
0
0
105
576
1.85
8.01
2.1
1.4
—
24.4
—
0
14
31
99
3.15
7.95
1.1
1.2
—
—
—
0
0
1122
9682
1.25
7.75
1.8
1.9
98.7
96.1
pmol/l
0.96
590
5150
848
7086
1.27
7.73
5.3
4.0
15.9
9.1
mg/mmol
1.96
579
4531
814
6769
1.27
7.72
4.6
3.6
—
—
—
0
0
203
1346
1.54
7.62
2.9
2.2
5805.8
5905.1
u/l
0.02
86
538
100
551
1.84
7.54
4.1
2.4
95.1
108.1
ug/min
0.16
73
347
95
516
1.87
7.50
6.0
3.7
—
—
—
0
0
217
1466
1.52
7.47
7.2
7.4
24.4
24.5
mmol/l
0.14
205
1363
76
384
2.00
7.42
1.3
1.6
—
—
—
0
0
247
1717
1.48
7.40
3.9
3.4
4.5
4.5
pmol/l
0.06
229
1537
100
564
1.80
7.02
1.5
1.2
280.0
255.0
u/ml
0.36
80
341
161
1033
1.59
6.99
1.3
1.2
0.2
0.9
u/ml
1.62
15
89
255
1807
1.45
6.93
2.0
2.2
12.9
12.6
nmol/l
0.30
236
1610
159
1021
1.59
6.89
1.3
1.3
219.3
224.9
miu/ml
0.07
73
491
470
3698
1.32
6.72
2.4
2.2
29.3
29.7
s
0.80
453
3579
734
6133
1.26
6.53
1.3
1.3
1.2
1.6
u/ml
0.61
238
1626
14
29
4.84
6.45
17.8
7.8
4.9
6.1
mmol/l
0.78
14
29
366
2797
1.35
6.38
1.4
1.3
—
—
—
0
0
799
6764
1.24
6.30
4.3
3.3
569.6
364.5
mg/l
0.48
538
4336
836
7121
1.24
6.22
5.1
4.7
2.3
2.7
ug/l
0.82
757
6403
129
815
1.61
6.02
1.4
1.3
10.3
10.1
u/l
0.04
111
664
21
63
3.35
5.99
1.4
1.6
—
—
—
0
0
267
1962
1.39
5.94
3.4
2.8
10.1
10.6
g/l
1.09
257
1799
252
1838
1.40
5.86
3.2
2.7
65.8
66.7
g/l
1.14
236
1696
756
6420
1.23
5.72
8.0
6.6
—
—
—
0
0
113
704
1.63
5.60
5.1
4.1
3.9
3.9
mmol/l
0.09
107
653
43
196
2.21
5.56
2.4
2.2
17.7
13.2
%
0.66
15
89
51
249
2.07
5.55
2.5
2.5
1.1
1.2
e9/l
0.65
38
150
864
7466
1.22
5.49
4.1
3.2
7.2
7.8
mmol/l
3.61
770
6349
68
374
1.84
5.27
1.2
1.2
—
—
—
0
0
123
795
1.57
5.26
1.3
1.2
—
—
—
0
0
418
3346
1.29
5.22
2.1
1.6
—
—
—
0
0
25
91
2.76
5.20
1.0
1.1
—
—
—
0
0
27
103
2.64
5.14
1.3
2.2
—
—
—
0
0
51
258
1.99
5.08
3.6
2.6
—
—
—
0
0
81
476
1.72
5.04
3.8
2.6
16.3
16.4
%
0.07
50
242
209
1524
1.40
4.90
4.6
5.4
—
—
—
0
0
290
2231
1.33
4.85
6.6
8.9
120.4
122.2
g/l
0.76
278
2144
56
298
1.90
4.83
2.0
1.6
—
—
—
0
0
56
298
1.90
4.83
2.0
1.6
—
—
—
0
0
56
298
1.90
4.83
2.0
1.6
—
—
—
0
0
56
298
1.90
4.83
2.0
1.6
—
—
—
0
0
22
79
2.80
4.71
3.2
2.3
—
—
—
0
0
248
1874
1.35
4.68
2.4
2.8
70.8
71.0
e9/l
0.04
200
1409
134
908
1.50
4.66
2.2
2.0
2.1
1.8
ug/l
0.15
129
806
551
4618
1.23
4.63
1.3
1.3
20.5
31.0
iu/ml
2.28
172
1434
730
6298
1.21
4.60
4.9
4.3
—
—
—
0
0
252
1914
1.34
4.60
2.5
2.3
8.0
7.2
ug/l
0.17
231
1716
306
2392
1.31
4.58
6.4
8.6
96.2
95.8
%
0.61
295
2304
42
206
2.05
4.58
3.0
3.2
68.1
42.3
mg/l
0.21
30
152
731
6311
1.21
4.57
2.5
2.1
2.8
2.9
mg/l
0.30
666
5390
24
92
2.62
4.56
1.0
1.0
—
—
—
0
0
70
408
1.73
4.52
4.1
2.9
—
—
—
0
0
167
1190
1.43
4.49
4.9
3.2
—
—
—
0
0
139
957
1.47
4.48
1.5
1.2
—
—
—
0
0
54
293
1.86
4.42
1.6
1.4
243.2
293.6
pmol/l
0.87
39
229
2382
22760
1.20
4.33
21.4
16.5
332.9
332.6
g/l
0.79
2372
22603
85
530
1.62
4.28
6.1
4.4
2.4
2.4
mmol/l
0.00
56
356
91
577
1.59
4.28
1.3
1.3
—
—
—
0
0
431
3548
1.25
4.26
2.4
2.1
—
—
—
0
0
170
1228
1.41
4.25
2.1
2.3
—
—
—
0
0
144
1010
1.45
4.23
2.3
1.8
1.4
1.5
g/l
1.55
136
877
252
1950
1.32
4.08
9.2
9.1
—
—
—
0
0
187
1385
1.37
4.04
1.9
3.1
53.3
45.1
u/ml
0.18
179
1335
136
955
1.44
3.99
4.2
6.1
0.9
0.9
%
0.32
130
889
348
2821
1.26
3.93
22.6
22.7
1.2
1.3
inr
1.15
30
422
204
1541
1.35
3.90
2.2
1.8
1.2
1.4
g/l
0.55
192
1421
556
4748
1.21
3.86
2.0
1.6
—
—
—
0
0
517
4403
1.21
3.68
1.3
1.3
15.5
11.5
u/ml
0.15
231
1774
487
4124
1.21
3.68
1.7
1.7
1321.9
1177.5
nmol/l
3.09
400
3153
95
632
1.52
3.67
5.7
4.3
7.4
7.4
ph
0.89
84
522
662
5771
1.19
3.65
2.1
1.9
—
—
—
0
0
47
262
1.81
3.60
1.9
1.4
—
—
—
0
0
134
959
1.42
3.58
4.3
6.0
1.4
1.7
%
3.71
128
891
328
2672
1.25
3.57
6.2
8.1
5.1
5.1
kpa
0.33
311
2549
328
2673
1.25
3.56
6.2
8.1
12.4
12.6
kpa
0.23
312
2551
328
2675
1.25
3.53
6.2
8.1
1.0
1.1
mmol/l
0.11
246
2077
224
1743
1.31
3.51
1.6
1.4
—
—
—
0
0
42
738
0.56
3.46
1.2
1.4
—
—
—
0
0
64
394
1.64
3.46
1.4
1.4
—
—
—
0
0
42
734
0.57
3.40
1.2
1.4
—
—
—
0
0
24
107
2.25
3.38
1.1
1.3
—
—
—
0
0
44
756
0.58
3.35
1.3
1.5
—
—
—
0
0
36
190
1.91
3.29
2.7
2.6
705.5
701.4
e6/l
0.01
11
79
450
3826
1.21
3.26
3.8
2.8
2.7
2.5
e6/l
0.14
280
2043
27
130
2.09
3.18
1.3
1.1
1815.4
1590.6
miu/ml
0.50
27
130
64
404
1.60
3.16
1.3
1.2
—
—
—
0
0
190
1472
1.31
3.11
8.1
10.0
94.1
94.0
%
0.06
190
1465
191
1484
1.31
3.06
7.9
9.9
0.7
0.7
%
1.73
191
1474
138
1022
1.37
3.06
1.7
1.5
11.9
18.5
u/ml
—
6
26
429
3655
1.20
3.04
1.5
1.3
514.9
527.7
titre
0.05
95
749
62
950
0.65
2.98
1.8
2.0
—
—
—
0
0
190
1482
1.30
2.97
7.9
9.8
1.4
1.4
%
0.22
190
1473
15
57
2.64
2.96
1.5
1.2
—
—
—
0
0
609
5362
1.17
2.94
1.9
1.4
2.2
2.3
g/l
0.82
427
3371
20
88
2.28
2.93
1.9
1.7
—
—
—
0
0
18
76
2.38
2.89
1.2
1.4
—
—
—
0
0
18
76
2.38
2.89
2.1
1.6
—
—
—
0
0
44
259
1.71
2.87
1.7
1.4
2.8
2.9
g/l
0.15
34
179
44
259
1.71
2.87
1.7
1.4
0.3
0.4
g/l
1.07
34
178
44
260
1.70
2.83
1.7
1.4
5.9
6.7
g/l
1.02
34
180
244
2989
0.80
2.83
1.3
1.3
—
—
—
0
0
39
223
1.76
2.81
1.0
1.1
—
—
—
0
0
129
1713
0.74
2.81
1.9
1.7
—
—
—
0
0
85
588
1.46
2.80
4.7
3.2
24.5
24.8
mmol/l
0.24
80
517
76
516
1.48
2.75
3.3
2.3
127.3
130.9
g/l
0.74
61
373
32
175
1.84
2.68
1.3
1.2
—
—
—
0
0
26
133
1.96
2.65
1.5
1.6
1.5
7.7
nmol/l
1.06
21
110
98
705
1.40
2.63
1.4
1.4
292.1
289.5
ug/g
0.04
56
396
85
1189
0.71
2.58
1.9
2.0
—
—
—
0
0
79
1116
0.70
2.55
1.9
2.1
—
—
—
0
0
1060
9785
1.13
2.53
3.2
2.6
—
—
—
0
0
24
122
1.97
2.50
1.3
1.1
—
4.7
—
0
6
88
1215
0.72
2.49
1.8
2.0
—
—
—
0
0
34
195
1.75
2.46
2.7
3.0
11.2
11.3
%
0.04
34
195
88
1210
0.72
2.43
1.8
2.0
—
—
—
0
0
484
4257
1.16
2.37
2.9
2.9
2.4
2.4
mmol/l
1.55
428
3738
110
823
1.35
2.36
2.5
2.4
514.6
478.0
ug/l
0.06
101
766
302
2554
1.20
2.35
3.2
2.8
1.8
1.8
%
0.10
285
2276
649
5834
1.14
2.34
2.1
1.8
1.0
1.1
mg/l
0.42
507
4395
88
1201
0.72
2.34
1.8
2.0
—
—
—
0
0
32
535
0.59
2.30
2.5
2.6
—
—
—
0
0
62
423
1.48
2.25
2.2
2.2
5.0
5.7
umol/l
0.26
47
307
36
216
1.67
2.25
1.1
1.1
220.6
252.8
mg/l
0.69
31
188
32
186
1.73
2.24
1.2
1.1
—
—
—
0
0
142
1112
1.29
2.23
1.1
1.1
2.4
0.9
u/ml
—
6
12
29
164
1.78
2.23
3.6
2.8
44.0
41.1
%
—
5
55
840
7698
1.12
2.23
1.5
1.5
—
—
—
0
0
9
29
3.11
2.22
1.9
1.3
138.4
116.7
ng/l
—
9
29
272
2293
1.20
2.21
3.6
4.1
5.1
22.2
ug/l
3.04
206
1831
104
782
1.34
2.18
1.1
1.1
15.2
4.1
u/ml
0.66
16
111
220
1819
1.23
2.17
2.4
2.4
16.8
21.0
au/ml
0.33
11
114
38
234
1.63
2.17
1.2
1.2
—
—
—
0
0
352
3042
1.18
2.16
1.5
1.4
—
—
—
0
0
184
1497
1.24
2.12
2.3
2.5
—
—
—
0
0
566
5084
1.14
2.06
1.6
1.6
12134325.4
35068090.1
pmol/l
0.92
478
4286
48
317
1.52
2.06
1.3
1.3
—
—
—
0
0
189
1549
1.23
2.05
1.3
1.3
26.2
28.1
iu/l
0.36
169
1316
264
2244
1.19
1.98
6.6
3.7
—
—
—
0
0
269
2292
1.19
1.97
2.5
2.2
0.2
0.2
g/l
1.10
257
2150
5
11
4.55
1.94
1.0
1.0
—
—
—
0
0
33
203
1.63
1.92
1.2
1.1
—
—
—
0
0
27
159
1.70
1.85
1.2
1.2
—
—
—
0
0
40
261
1.54
1.84
5.4
4.8
263.6
81.1
u/ml
0.36
12
72
6
17
3.53
1.83
1.0
1.2
—
—
—
0
0
15
73
2.06
1.80
3.9
2.3
163.0
145.3
e6/l
—
10
38
370
3260
1.15
1.80
1.9
1.7
—
—
—
0
0
240
2044
1.19
1.79
7.3
7.7
1.3
1.4
mmol/l
0.57
225
1965
216
1826
1.20
1.75
3.1
2.9
171.0
185.0
ng/l
0.22
204
1653
126
1007
1.26
1.74
2.7
2.2
21.6
21.2
s
0.27
113
874
60
432
1.40
1.71
1.2
1.2
—
—
—
0
0
11
48
2.30
1.70
2.3
1.8
—
—
—
0
0
197
1657
1.20
1.69
1.3
1.3
72.4
50.0
au/ml
—
5
73
55
391
1.41
1.68
1.4
1.4
54.4
63.8
mmol/l
1.36
42
324
139
1129
1.24
1.68
1.6
1.4
—
—
—
0
0
36
235
1.54
1.67
2.0
2.2
—
—
—
0
0
107
846
1.27
1.63
2.7
2.6
—
—
—
0
0
63
462
1.37
1.62
1.4
1.7
—
—
—
0
0
77
584
1.33
1.60
1.3
1.5
1818.0
1174.4
e6/l
0.14
71
477
77
584
1.33
1.60
1.2
1.4
20.4
30.3
e6/l
0.20
70
452
6
20
3.00
1.58
1.3
1.1
—
—
—
0
0
20
114
1.76
1.56
1.2
1.6
—
—
—
0
0
44
305
1.45
1.56
1.2
1.3
—
—
nmol/l
—
0
0
13
246
0.53
1.53
2.9
2.7
—
—
—
0
0
18
100
1.80
1.53
2.4
2.3
1.3
1.1
ug/l
0.24
18
92
68
511
1.34
1.52
1.3
1.5
0.5
0.4
nmol/l
0.29
50
405
128
1045
1.23
1.51
1.0
1.1
—
—
—
0
0
26
162
1.61
1.49
8.1
6.8
—
—
—
0
0
59
436
1.36
1.48
1.4
1.3
2.5
3.9
ug/l
1.35
50
398
58
428
1.36
1.46
2.2
1.5
—
—
—
0
0
67
506
1.33
1.46
3.0
3.7
—
—
—
0
0
38
260
1.47
1.45
1.7
1.5
280.8
280.3
mosm/kgh2o
0.06
30
204
12
59
2.04
1.43
1.2
1.1
—
—
—
0
0
12
59
2.04
1.43
1.2
1.1
—
—
—
0
0
12
59
2.04
1.43
1.2
1.1
—
—
—
0
0
349
3125
1.13
1.38
1.7
1.8
—
—
—
0
0
714
6659
1.09
1.32
1.7
1.6
1.3
1.4
mmol/l
0.55
605
5644
138
1156
1.20
1.30
2.3
1.8
—
—
—
0
0
2495
24478
1.10
1.29
15.6
13.9
39.6
40.0
%
1.15
1741
18504
26
170
1.53
1.25
1.0
1.1
8.9
10.7
iu/ml
—
10
51
65
502
1.30
1.25
4.4
3.2
—
—
—
0
0
6
25
2.40
1.24
1.0
1.0
—
—
—
0
0
66
844
0.78
1.24
2.2
2.8
—
—
—
0
0
679
6338
1.09
1.23
4.7
3.9
92.4
91.9
%
0.21
661
6171
387
3515
1.12
1.22
1.2
1.2
—
—
—
0
0
247
2183
1.14
1.21
1.6
1.4
—
—
—
0
0
20
124
1.62
1.20
2.1
1.9
—
—
—
0
0
853
8050
1.08
1.19
2.6
2.3
—
—
—
0
0
32
222
1.45
1.18
1.4
1.4
1.6
1.5
nmol/l
0.20
27
196
18
109
1.66
1.18
1.1
1.1
—
—
—
0
0
133
1123
1.19
1.17
6.7
4.2
23.7
24.1
mmol/l
0.88
120
1019
54
415
1.31
1.10
1.6
1.6
0.5
0.8
g/l
1.03
44
316
7
136
0.51
1.09
2.6
2.1
3.0
2.2
ug/l
—
7
116
580
5407
1.09
1.09
1.6
1.5
20.7
20.5
nmol/l
0.10
517
4690
45
592
0.76
1.07
2.8
2.0
—
—
—
0
0
73
586
1.25
1.07
1.1
1.1
1.2
1.3
u/ml
0.08
25
228
169
1476
1.15
1.02
5.5
3.6
5.1
5.2
kpa
0.33
164
1376
40
530
0.75
1.02
1.4
1.3
—
—
—
0
0
167
1458
1.15
1.01
5.5
3.6
7.4
7.4
ph
0.25
34
185
35
256
1.37
1.00
4.8
6.1
7.8
7.3
mmol/l
0.33
27
216
81
667
1.22
0.97
1.1
1.1
—
—
—
0
0
17
259
0.65
0.96
1.0
1.2
—
—
—
0
0
67
822
0.81
0.94
12.2
9.1
—
—
—
0
0
22
151
1.46
0.90
1.3
1.4
5.5
5.8
mmol/l
0.57
22
146
24
168
1.43
0.89
1.6
1.4
2240.7
2102.1
ml
—
9
31
30
219
1.37
0.89
1.7
1.5
35.1
32.6
%
0.13
18
137
8
43
1.86
0.87
1.0
1.3
—
—
—
0
0
8
43
1.86
0.87
1.0
1.3
—
—
—
0
0
8
43
1.86
0.87
1.0
1.3
—
—
—
0
0
224
2021
1.12
0.85
1.3
1.2
96.7
151.4
iu/ml
2.08
96
765
33
247
1.34
0.85
1.2
1.3
169291.2
91572.6
e6/l
0.19
21
167
99
1157
0.85
0.85
1.1
1.1
—
—
—
0
0
19
129
1.48
0.83
1.7
3.2
7.4
7.4
ph
—
9
43
8
139
0.57
0.83
1.3
1.2
—
—
—
0
0
25
180
1.39
0.82
1.0
1.0
—
—
—
0
0
241
2190
1.11
0.81
1.1
1.2
—
—
—
0
0
80
673
1.19
0.80
3.2
3.6
38.8
77.5
mg/l
1.01
60
548
80
673
1.19
0.80
3.2
3.6
61.3
64.9
mg/l
0.09
58
547
19
130
1.46
0.80
2.2
2.7
487.8
1169.3
u/ml
2.33
19
130
6
33
1.82
0.79
3.2
10.3
—
—
—
0
0
6
33
1.82
0.79
1.0
1.2
—
640.5
—
0
9
194
1748
1.12
0.77
1.2
1.2
—
—
—
0
0
48
385
1.25
0.77
1.9
1.6
—
—
—
0
0
60
723
0.83
0.75
1.1
1.2
—
—
—
0
0
17
117
1.46
0.71
1.5
1.4
—
—
—
0
0
12
76
1.58
0.71
5.2
3.2
—
—
—
0
0
65
546
1.19
0.69
4.9
8.4
11.6
11.4
mmol/l
0.17
60
485
65
547
1.19
0.68
4.9
8.4
105.7
105.5
mmol/l
0.21
60
486
5
28
1.79
0.66
1.0
1.3
—
—
—
0
0
5
28
1.79
0.66
1.2
1.3
—
—
—
0
0
12
179
0.67
0.66
1.4
1.3
—
1.5
—
0
10
89
776
1.15
0.62
4.3
7.1
1.3
1.3
mmol/l
0.11
78
669
26
199
1.31
0.62
2.0
2.1
—
1.8
—
0
12
37
297
1.25
0.62
2.2
2.3
—
—
—
0
0
24
182
1.32
0.61
1.1
1.1
1.1
1.0
ratio
—
8
75
13
187
0.69
0.61
1.5
1.5
—
67.4
—
0
20
9
139
0.65
0.60
1.6
1.3
—
—
—
0
0
22
165
1.34
0.60
1.2
1.1
—
4.4
nmol/l
—
0
33
27
209
1.29
0.60
1.0
1.0
—
—
—
0
0
8
52
1.54
0.59
1.0
1.0
—
—
—
0
0
46
381
1.21
0.59
1.2
1.2
25.9
35.6
u/l
0.32
40
327
52
437
1.19
0.58
1.0
1.1
3.5
3.7
u/ml
0.03
23
155
25
193
1.30
0.57
1.2
1.0
—
—
—
0
0
6
36
1.67
0.56
1.2
1.0
—
—
—
0
0
479
4560
1.06
0.55
3.9
3.5
617.7
457.8
ng/l
0.30
340
3279
68
588
1.16
0.55
1.6
1.7
27227.8
13250.4
e6/l
0.29
45
431
61
524
1.17
0.54
8.8
2.2
0.9
0.8
nmol/l
0.43
54
438
12
82
1.47
0.54
1.0
1.1
0.1
3.1
u/ml
—
5
46
20
151
1.33
0.54
1.1
1.6
5.0
7.8
u/l
1.37
15
128
6
39
1.54
0.53
1.2
1.1
—
—
—
0
0
26
206
1.26
0.51
2.1
1.4
0.9
1.0
g/l
0.68
26
206
17
222
0.76
0.47
1.4
1.6
—
—
—
0
0
59
676
0.87
0.47
2.1
2.4
36.4
38.0
g/l
1.11
52
599
8
118
0.68
0.45
1.3
1.2
—
—
—
0
0
140
1287
1.09
0.45
6.7
11.2
—
—
—
0
0
24
193
1.25
0.43
1.3
1.1
—
—
—
0
0
53
461
1.15
0.43
1.2
1.2
—
—
—
0
0
44
511
0.86
0.43
2.4
3.0
32.6
33.9
umol/l
0.13
39
442
46
397
1.16
0.42
1.0
1.1
2.7
4.4
u/ml
0.84
19
153
35
295
1.19
0.41
1.7
1.6
58.2
58.9
%
0.03
20
190
5
33
1.52
0.41
1.6
6.0
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
1.2
—
0
9
0
15
0.00
0.41
0.0
1.7
—
69.0
—
0
10
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
44
379
1.16
0.41
3.3
3.2
0.9
0.8
nmol/l
0.10
35
298
0
17
0.00
0.40
0.0
1.6
—
—
—
0
0
435
4176
1.05
0.40
3.0
3.0
0.7
0.7
ug/l
0.00
281
2698
13
171
0.76
0.39
1.2
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
3.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
0.3
—
0
7
0
19
0.00
0.39
0.0
1.0
—
0.3
—
0
11
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
52
457
1.14
0.38
1.2
1.1
—
—
—
0
0
20
247
0.81
0.38
3.1
1.7
37.1
24.1
ug/l
0.32
20
242
14
181
0.77
0.38
1.1
1.1
—
—
—
0
0
194
1825
1.07
0.37
1.8
2.8
4.6
4.1
e9/l
1.70
170
1481
56
496
1.13
0.37
1.0
1.1
2.3
2.4
u/ml
0.03
16
112
27
322
0.84
0.37
1.3
1.2
—
—
—
0
0
17
212
0.80
0.35
1.6
1.5
—
—
—
0
0
10
73
1.37
0.34
2.0
1.7
—
164.1
—
0
9
6
44
1.36
0.34
3.5
2.0
—
—
—
0
0
77
700
1.10
0.34
1.4
1.2
69.1
94.5
titre
0.73
11
56
52
462
1.13
0.34
1.1
1.1
—
—
—
0
0
114
1229
0.92
0.34
8.9
10.5
24.0
24.3
mmol/l
0.71
102
1163
91
836
1.09
0.33
4.8
3.4
0.3
0.3
g/l
0.10
48
342
245
2569
0.95
0.32
1.5
1.4
—
—
—
0
0
300
2876
1.05
0.31
3.6
2.7
6.2
7.8
umol/l
1.42
269
2500
124
1157
1.07
0.31
1.9
1.7
293.7
296.0
mu/l
0.04
118
1043
223
2343
0.95
0.31
6.5
4.1
—
—
—
0
0
49
438
1.12
0.30
1.4
1.2
6.0
5.0
u/ml
0.16
24
187
17
206
0.82
0.29
1.2
1.2
—
—
—
0
0
63
690
0.91
0.28
1.4
1.2
1.4
2.4
u/ml
—
6
74
43
481
0.89
0.28
1.1
1.1
—
—
—
0
0
37
417
0.89
0.27
2.2
1.8
—
—
—
0
0
15
122
1.23
0.27
1.2
1.1
294.4
204.5
iu/ml
0.21
15
122
22
257
0.86
0.26
1.3
1.7
—
—
—
0
0
43
478
0.90
0.26
1.1
1.1
—
—
—
0
0
66
717
0.92
0.25
1.6
1.3
—
—
—
0
0
5
75
0.67
0.25
1.2
1.2
—
—
—
0
0
48
434
1.11
0.25
1.7
1.6
—
—
—
0
0
20
235
0.85
0.25
7.9
3.4
—
—
—
0
0
85
791
1.08
0.25
3.1
3.6
314.8
5168.0
u/ml
0.78
70
680
17
142
1.20
0.24
1.4
1.3
146.8
133.8
nmol/l
0.95
17
142
30
264
1.14
0.24
1.1
1.1
—
—
—
0
0
20
170
1.18
0.24
1.1
1.2
—
—
—
0
0
46
417
1.10
0.24
1.2
1.0
3.8
2.4
u/ml
0.29
24
202
49
537
0.91
0.23
3.2
3.5
17.7
24.6
mg/l
1.55
32
339
5
38
1.32
0.23
1.0
1.1
—
—
—
0
0
41
453
0.90
0.23
2.1
1.7
—
—
—
0
0
13
106
1.23
0.23
1.2
1.6
—
—
—
0
0
5
40
1.25
0.22
1.6
1.7
—
—
—
0
0
7
93
0.75
0.22
1.3
1.2
—
—
—
0
0
35
314
1.12
0.22
2.0
2.6
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
33
296
1.12
0.21
2.5
2.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
6
49
1.22
0.20
1.3
1.3
—
—
—
0
0
28
250
1.12
0.19
1.4
1.4
9.3
12.1
mmol/l
—
6
56
12
100
1.20
0.18
1.0
1.1
—
—
—
0
0
18
157
1.15
0.17
1.4
1.2
—
—
—
0
0
603
6133
0.98
0.17
2.5
2.3
—
—
—
0
0
63
591
1.07
0.17
1.3
1.2
—
—
—
0
0
11
131
0.84
0.17
1.1
1.1
—
—
—
0
0
5
68
0.73
0.17
1.0
1.6
—
—
—
0
0
175
1811
0.96
0.16
1.5
1.4
—
—
—
0
0
14
120
1.17
0.16
1.1
3.1
80.9
136.3
umol/l
—
7
74
8
73
1.10
0.15
1.0
1.0
—
—
—
0
0
29
264
1.10
0.15
5.7
3.9
—
—
—
0
0
24
216
1.11
0.15
1.7
1.2
1.3
0.5
u/ml
0.54
14
86
16
182
0.88
0.15
19.0
18.1
1623.5
1532.6
nmol/l
0.24
16
177
10
118
0.85
0.14
2.9
1.8
—
—
—
0
0
88
919
0.96
0.13
6.0
3.8
24.1
24.8
mmol/l
2.07
83
854
15
170
0.88
0.13
1.1
1.0
—
—
—
0
0
16
180
0.89
0.13
11.4
13.2
1016.3
854.4
nmol/l
0.64
16
174
56
531
1.06
0.12
1.1
1.1
3.1
5.6
u/ml
1.41
30
277
110
1063
1.04
0.12
5.9
3.7
—
—
—
0
0
13
114
1.14
0.11
1.6
2.7
—
—
—
0
0
72
690
1.04
0.11
1.9
2.0
2.9
4.8
iu/l
3.66
27
253
46
435
1.06
0.11
1.3
1.2
—
—
—
0
0
17
187
0.91
0.10
1.4
2.0
1.9
1.9
u/field
—
7
90
24
222
1.08
0.10
1.6
1.5
—
—
—
0
0
21
193
1.09
0.10
1.6
2.3
—
—
—
0
0
5
46
1.09
0.09
1.0
1.1
—
8.8
—
0
7
5
48
1.04
0.09
1.2
1.1
—
—
—
0
0
75
724
1.04
0.09
3.9
3.2
—
—
—
0
0
160
1635
0.98
0.09
2.5
2.7
—
—
—
0
0
235
2387
0.98
0.08
3.7
2.4
31.6
59.1
u/l
0.77
208
2040
6
75
0.80
0.07
1.0
1.1
—
—
—
0
0
38
398
0.95
0.07
1.3
1.5
—
—
—
0
0
9
87
1.03
0.07
1.2
1.7
—
—
—
0
0
23
216
1.07
0.06
1.2
1.1
—
—
—
0
0
9
101
0.89
0.06
2.4
2.6
—
—
—
0
0
1787
17830
1.01
0.04
3.4
3.0
43.3
45.2
u/l
0.49
1705
16812
26
271
0.96
0.04
1.2
1.4
—
—
—
0
0
52
508
1.02
0.03
1.1
1.1
0.6
1.3
u/ml
0.71
19
210
10
92
1.09
0.03
1.4
1.2
—
—
—
0
0
11
102
1.08
0.03
1.0
1.1
—
4.6
—
0
16
11
102
1.08
0.03
1.2
1.1
—
—
—
0
0
18
188
0.96
0.02
2.0
1.4
—
—
—
0
0
21
202
1.04
0.02
1.7
1.5
—
—
—
0
0
55
541
1.02
0.02
1.1
1.5
—
—
—
0
0
11
103
1.07
0.02
1.3
1.0
—
—
—
0
0
11
103
1.07
0.02
1.6
3.0
—
—
—
0
0
11
116
0.95
0.00
1.6
2.9
—
—
—
0
0
13
135
0.96
0.00
1.2
1.7
—
—
—
0
0
12
119
1.01
0.00
1.7
1.6
—
—
—
0
0
13
131
0.99
0.00
2.2
2.4
—
—
—
0
0
15
151
0.99
0.00
9.4
3.6
—
—
—
0
0
43
425
1.01
0.00
1.2
1.1
55.0
1283.5
iu/ml
—
10
105
27
269
1.00
0.00
1.1
1.5
—
—
—
0
0
12
116
1.03
0.00
1.4
2.1
22.9
290.0
ug/l
0.67
12
103
37
366
1.01
0.00
1.0
1.0
1.1
0.4
u/ml
—
8
81
103
1033
1.00
0.00
1.7
1.6
—
—
—
0
0
22
223
0.99
0.00
1.6
1.5
12107.8
103567.1
e6/l
1.76
17
134
0
5
0.00
0.00
0.0
1.2
—
40.1
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
2.4
—
4.7
—
0
5
0
5
0.00
0.00
0.0
1.6
—
2923.3
—
0
5
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
2.9
—
0
5
0
6
0.00
0.00
0.0
1.2
—
66.1
—
0
6
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
9
91
0.99
0.00
1.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
8.0
—
—
—
0
0
9
89
1.01
0.00
4.3
13.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
0.00
2.8
2.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
9
89
1.01
0.00
3.8
1.7
—
—
—
0
0
5
53
0.94
0.00
10.6
6.8
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
6
64
0.94
0.00
3.2
2.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_MELANOCYTIC_NOS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_NOS 0.99 [0.86, 1.14] 0.892
Birth year 0.999 [0.99, 1.01] 0.747

During the follow-up period (1.1.1998 — 31.12.2019), 535 out of 7816 females with CD2_BENIGN_MELANOCYTIC_NOS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_MELANOCYTIC_NOS 0.989 [0.85, 1.15] 0.881
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 635 out of 5629 males with CD2_BENIGN_MELANOCYTIC_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_MELANOCYTIC_NOS.

N-year risk Females Males
1 0.105% 0.211%
5 0.691% 1.035%
10 1.699% 2.722%
15 3.148% 5.373%
20 5.272% 9.206%

Relationships between endpoints

Index endpoint: CD2_BENIGN_MELANOCYTIC_NOS – Melanocytic naevi, other sites/unspecified

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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