≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback

Other mycoses, not elsewhere classified/unspecified

Endpoint Browser PheWeb

AB1_MYSOSIS_NOS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — B48, B49
  • Hospital discharge: ICD-9 — 11[7-9]
  • Hospital discharge: ICD-8 — 117
  • Hospital discharge: excluded ICD-9 — 117[1-5]
  • Hospital discharge: excluded ICD-8 — 117[1-3]
  • Cause of death: ICD-10 — B48, B49
  • Cause of death: ICD-9 — 11[7-9]
  • Cause of death: ICD-8 — 117
  • Cause of death: excluded ICD-9 — 117[1-5]
  • Cause of death: excluded ICD-8 — 117[1-3]

2 out of 7 registries used, show all original rules.

129

4. Check minimum number of events

None

129

5. Include endpoints

None

129

6. Filter based on genotype QC (FinnGen only)

123

Control definitions (FinnGen only)

Control exclude
AB1_MYCOSES

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1022 457 554
Only index persons 724 330 394
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.02
Only index persons 0.01 0.01 0.02
Median age at first event (years)
Whole population 56.38 57.52 55.64
Only index persons 53.71 56.31 51.53

-FinnGen-

Key figures

All Female Male
Number of individuals 123 55 68
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 64.43 61.62 66.70

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
129
Matched controls
1290
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B49
ICD-10 Finland
Unspecified mycosis
+∞
46.7
42
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
11.0
27.0
33
39
B48.5
ICD-10 Finland
Pneumocystosis
+∞
27.0
25
*
B48.8
ICD-10 Finland
Other specified mycoses
+∞
25.9
24
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.8
22.5
69
213
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
9.4
20.8
28
37
B48.7
ICD-10 Finland
Opportunistic mycoses
+∞
20.3
19
*
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
+∞
20.3
19
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.6
14.7
27
50
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.7
14.5
43
123
TGC00
NOMESCO Finland
Bronchial lavation
16.3
13.8
22
16
XW000
NOMESCO Finland
Bone marrow biopsy
14.5
13.2
22
18
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
7.0
13.1
22
37
A41.9
ICD-10 Finland
Sepsis, unspecified
13.7
12.9
22
19
J02AC03
ATC
voriconazole; systemic
77.7
12.9
14
*
R50.9
ICD-10 Finland
Fever, unspecified
4.3
12.2
39
117
127
Kela drug reimbursment
Transplant complication
33.6
11.9
15
5
J01MA14
ATC
moxifloxacin; systemic
5.1
11.7
28
66
JN4AD
NOMESCO Finland
Body CT examination
5.1
11.5
28
67
WX892
NOMESCO Finland
Monitored bed care
5.9
11.5
23
46
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.0
11.3
28
68
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.7
11.3
31
82
D64.9
ICD-10 Finland
Anaemia, unspecified
4.8
11.0
29
74
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.2
10.8
20
37
A04AA01
ATC
ondansetron; systemic, rectal
5.3
10.2
23
51
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
10.2
80
422
L04AA06
ATC
mycophenolic acid; systemic
28.6
10.0
13
5
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
12.8
9.9
17
15
H02AB06
ATC
prednisolone; systemic
3.2
9.6
78
415
ZX120
NOMESCO Finland
Intravenous
4.6
9.4
25
64
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.4
8.8
25
67
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
8.5
51
225
C03CA01
ATC
furosemide; systemic
3.0
8.4
54
247
11799
ICD-8 Finland
Other systemic mycosis, Unspecified
+∞
8.4
8
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.4
8.4
23
60
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
35.8
8.2
10
*
A41.8
ICD-10 Finland
Other specified sepsis
16.4
7.9
12
8
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.7
7.9
29
94
L04AX01
ATC
azathioprine; systemic
11.1
7.7
14
14
JN4BD
NOMESCO Finland
Extensive body CT
3.6
7.6
29
96
L03AA02
ATC
filgrastim; parenteral
7.7
7.6
17
25
GD1AD
NOMESCO Finland
Thorax CT examination
6.6
7.6
19
33
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
7.0
7.6
18
29
J01MA12
ATC
levofloxacin; systemic
3.1
7.4
38
152
B37.7
ICD-10 Finland
Candidal sepsis
+∞
7.4
7
*
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
21.5
7.3
10
5
L04AD02
ATC
tacrolimus; systemic
32.0
7.2
9
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
4.6
7.1
18
44
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
7.0
46
210
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.5
6.9
18
45
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
17.9
6.9
10
6
XG410
NOMESCO Finland
Flow-volume spirometry
8.6
6.8
14
18
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.0
6.8
21
60
A07AA02
ATC
nystatin; oral
6.4
6.7
17
30
A28
ICPC
Limited function/disability NOS
3.3
6.7
30
110
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
73.3
6.5
7
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
19.2
6.4
9
5
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.7
6.3
22
68
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.2
6.3
18
48
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
10.8
6.2
11
11

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
62
130
8.26
31.88
4.1
1.3
—
—
—
0
0
42
77
7.61
23.80
7.2
2.4
7.72
9.87
g/l
2.03
42
69
43
87
6.91
22.04
4.4
2.8
75.87
68.23
e9/l
0.48
36
63
50
118
6.29
21.88
26.8
7.7
1.90
1.16
mmol/l
0.43
42
95
54
150
5.47
19.45
4.2
1.8
—
—
—
0
0
76
283
5.10
19.06
15.2
4.5
—
—
—
0
0
33
61
6.93
18.23
11.8
3.7
—
—
—
0
0
97
499
4.81
14.62
16.9
5.6
0.04
0.04
e9/l
0.11
92
436
34
80
5.41
14.42
9.4
4.0
1.04
0.97
%
0.09
25
33
93
468
4.54
14.34
24.1
6.2
—
—
—
0
0
45
135
4.58
14.23
21.6
6.0
1.09
1.03
mmol/l
0.81
45
128
98
517
4.73
14.04
19.0
5.9
0.17
0.18
e9/l
0.20
93
461
97
510
4.64
13.91
17.2
5.6
1.73
1.98
e9/l
0.45
92
458
21
34
7.18
12.92
1.8
1.3
—
—
—
0
0
30
70
5.28
12.75
9.2
4.2
0.73
0.44
%
0.63
22
25
18
10
20.65
12.46
1.4
1.6
—
—
—
0
0
18
11
18.76
12.07
2.8
3.0
—
—
—
0
0
22
22
11.81
12.07
1.9
1.3
—
—
—
0
0
35
97
4.58
12.07
15.2
4.2
2.46
2.45
mmol/l
0.00
25
79
88
466
3.80
11.68
21.1
5.6
2.33
2.68
%
0.82
82
435
89
480
3.75
11.37
21.6
5.8
23.17
27.47
%
2.24
83
448
39
127
3.97
10.76
1.4
1.4
533.33
336.92
titre
—
6
26
10
0
+∞
10.56
4.0
0.0
—
—
—
0
0
14
6
25.91
10.49
3.2
1.7
—
—
—
0
0
27
69
4.68
10.20
8.6
4.2
0.16
0.41
%
0.29
19
22
31
90
4.22
9.94
43.5
9.1
—
—
—
0
0
19
21
10.40
9.93
1.9
1.1
237.00
290.38
u/ml
0.16
14
13
39
134
3.74
9.89
36.0
7.9
103.59
103.71
mmol/l
0.06
39
134
89
515
3.35
9.45
34.7
7.3
1.19
1.21
mmol/l
2.53
80
438
39
143
3.48
8.87
5.0
2.2
28.41
22.95
%
0.87
32
129
46
194
3.13
8.27
2.3
1.9
—
—
—
0
0
23
62
4.30
8.05
50.3
7.2
—
—
—
0
0
25
73
4.01
7.87
8.6
4.2
0.24
0.19
%
0.10
17
26
29
98
3.53
7.38
2.0
1.3
—
—
—
0
0
14
16
9.66
7.26
5.0
2.0
—
—
—
0
0
12
10
13.07
7.24
1.3
1.0
—
—
—
0
0
42
185
2.88
6.83
7.9
3.5
394.58
163.36
ng/l
0.48
36
143
14
18
8.58
6.82
6.1
2.8
—
—
—
0
0
32
121
3.19
6.79
3.9
1.7
—
—
—
0
0
14
19
8.12
6.61
4.6
6.3
—
—
—
0
0
57
299
2.62
6.56
6.2
3.0
—
—
—
0
0
47
228
2.67
6.29
5.8
1.9
2.61
1.41
mg/l
0.95
39
173
17
44
4.30
6.21
16.7
3.1
1.65
1.34
%
0.33
17
44
10
8
13.41
6.19
1.2
1.1
—
—
—
0
0
37
160
2.84
6.16
2.3
1.7
—
—
—
0
0
11
11
10.80
6.16
6.3
3.2
—
—
—
0
0
50
259
2.52
5.78
21.9
8.2
—
—
—
0
0
13
20
7.10
5.72
2.8
1.6
—
—
—
0
0
32
134
2.85
5.62
2.4
1.7
—
—
—
0
0
13
21
6.76
5.55
3.2
2.1
27.23
24.73
mmol/l
1.11
13
21
59
336
2.39
5.49
8.7
2.4
—
—
—
0
0
9
8
11.97
5.38
1.2
1.0
—
—
—
0
0
75
478
2.36
5.35
18.5
12.0
1.06
1.21
inr
3.02
22
147
24
88
3.12
5.29
1.8
1.6
—
—
—
0
0
16
37
4.79
5.15
2.4
1.3
—
—
—
0
0
15
33
5.00
5.06
10.7
4.3
—
—
—
0
0
11
17
6.96
4.89
1.1
1.0
—
—
—
0
0
11
17
6.96
4.89
4.0
2.5
—
—
—
0
0
103
780
2.59
4.64
8.3
3.6
20.65
11.67
mm/h
4.48
98
704
8
8
10.56
4.58
1.0
1.3
—
—
—
0
0
16
50
3.51
4.51
7.7
3.7
—
—
—
0
0
24
99
2.75
4.28
1.6
1.4
—
—
—
0
0
40
214
2.26
4.11
2.1
1.3
2.39
2.40
g/l
0.01
29
131
10
18
5.92
4.06
26.3
2.8
—
—
—
0
0
10
18
5.92
4.06
1.1
1.0
—
—
—
0
0
10
18
5.92
4.06
1.4
1.7
—
—
—
0
0
14
43
3.53
4.04
19.3
3.1
0.58
0.68
%
0.39
14
43
43
240
2.19
3.97
6.1
3.3
—
—
—
0
0
62
403
2.04
3.81
2.5
1.9
94.98
96.37
pmol/l
0.07
41
205
51
312
2.05
3.67
14.2
4.3
7.38
7.40
ph
—
10
61
36
193
2.20
3.64
1.9
1.6
1272.55
1177.65
nmol/l
0.24
30
142
7
9
8.14
3.60
2.1
1.1
—
—
—
0
0
11
26
4.52
3.60
1.2
1.2
—
—
—
0
0
17
64
2.91
3.56
4.6
3.4
—
—
—
0
0
6
6
10.40
3.53
1.7
1.5
—
—
—
0
0
10
22
4.83
3.51
5.6
1.6
—
—
—
0
0
49
301
2.01
3.45
1.6
1.4
—
—
—
0
0
58
382
1.94
3.32
9.8
3.7
71.80
58.42
e6/l
0.09
47
265
6
7
8.91
3.30
1.0
1.3
—
—
—
0
0
52
333
1.94
3.21
8.2
3.5
2.30
2.35
mmol/l
1.48
47
294
12
35
3.67
3.20
5.8
4.1
—
—
—
0
0
9
20
4.75
3.18
1.7
1.3
—
—
—
0
0
5
5
10.33
3.00
6.0
1.4
1346.40
1073.20
u/ml
—
5
5
18
77
2.55
2.98
4.5
3.6
—
—
—
0
0
9
22
4.32
2.94
3.8
2.2
8.10
7.66
kpa
—
9
22
51
333
1.88
2.92
7.4
3.0
50.43
237.85
e6/l
0.46
44
252
91
714
1.93
2.90
8.8
4.0
—
—
—
0
0
58
398
1.83
2.82
3.1
2.2
—
—
—
0
0
5
6
8.60
2.77
1.6
1.0
—
—
—
0
0
7
14
5.22
2.77
1.7
1.4
—
—
—
0
0
31
174
2.03
2.74
1.3
1.2
24.99
27.36
iu/ml
—
10
62
36
215
1.94
2.67
4.5
2.3
3.23
3.68
e6/l
0.24
36
189
15
62
2.61
2.65
2.7
2.3
3.55
8.39
e9/l
—
10
53
6
11
5.66
2.57
3.7
4.2
—
—
—
0
0
69
510
1.76
2.54
5.6
3.4
0.00
0.00
estimate
—
9
95
13
51
2.72
2.53
1.9
3.8
3.92
4.46
pmol/l
1.14
13
46
16
71
2.43
2.46
1.4
1.3
—
—
—
0
0
9
27
3.50
2.44
1.0
1.3
—
—
titre
—
0
0
65
477
1.73
2.42
25.6
10.1
0.00
0.00
e9/l
-0.00
56
394
5
8
6.44
2.39
5.8
2.0
10.12
11.56
%
—
5
8
46
308
1.77
2.35
6.1
3.0
0.39
0.37
e6/l
0.04
41
228
57
407
1.72
2.32
5.1
3.4
111.07
57.04
ng/l
0.27
47
280
68
514
1.68
2.21
5.7
3.4
0.00
0.00
estimate
—
9
86
67
507
1.67
2.15
8.6
4.7
0.00
0.00
estimate
—
9
91
30
181
1.86
2.13
7.6
3.2
2.98
2.57
e6/l
0.09
19
100
18
93
2.09
1.97
1.6
1.9
—
—
—
0
0
6
16
3.88
1.96
4.2
2.1
—
—
—
0
0
42
295
1.63
1.74
6.7
2.8
—
—
—
0
0
12
57
2.22
1.61
1.0
1.4
—
—
—
0
0
25
157
1.73
1.55
1.2
1.3
59.01
10.09
u/ml
—
7
60
17
96
1.89
1.47
11.9
5.8
—
—
—
0
0
5
17
3.02
1.37
1.2
1.4
80.64
91.72
%
—
5
17
9
42
2.23
1.37
1.8
1.9
—
—
—
0
0
0
37
0.00
1.37
0.0
1.8
—
—
—
0
0
25
359
0.62
1.30
3.3
3.0
—
—
—
0
0
39
287
1.51
1.29
4.6
3.4
93.83
73.50
mg/l
0.18
27
189
41
308
1.49
1.22
4.9
4.0
14.61
10.57
mg/mmol
0.26
28
197
6
26
2.37
1.20
2.2
2.2
—
—
—
0
0
5
21
2.43
1.10
5.6
2.2
—
—
—
0
0
9
46
2.03
1.06
2.1
2.2
—
—
—
0
0
10
54
1.92
0.99
2.8
4.1
—
—
—
0
0
21
144
1.55
0.95
1.2
1.3
—
—
—
0
0
6
28
2.20
0.93
1.5
1.4
6.80
6.68
u/l
—
6
23
6
32
1.92
0.83
4.5
5.3
—
—
—
0
0
9
53
1.75
0.77
2.3
2.3
—
—
—
0
0
18
126
1.50
0.75
1.3
1.3
—
—
—
0
0
80
715
1.31
0.75
7.5
3.8
—
—
—
0
0
5
94
0.51
0.69
1.4
1.4
—
—
—
0
0
34
272
1.34
0.69
5.4
3.6
0.00
0.00
estimate
—
8
91
38
310
1.32
0.68
4.4
4.1
—
—
—
0
0
12
78
1.59
0.68
1.1
1.1
—
—
—
0
0
5
28
1.82
0.67
1.2
1.3
—
—
—
0
0
19
250
0.72
0.61
2.3
3.1
0.81
0.80
ug/l
0.02
13
174
14
98
1.48
0.59
1.9
2.1
10.34
13.17
nmol/l
0.64
14
89
6
37
1.65
0.56
1.5
1.2
—
—
—
0
0
12
83
1.49
0.54
8.8
4.2
1.23
1.23
mmol/l
0.01
12
76
98
923
1.26
0.47
5.7
4.4
1.72
1.95
mu/l
1.47
92
818
103
976
1.27
0.47
5.6
3.9
1.50
1.28
mmol/l
1.81
98
887
10
70
1.46
0.43
5.3
2.4
—
—
—
0
0
112
1084
1.25
0.32
49.5
12.9
—
—
—
0
0
108
1042
1.22
0.31
66.1
13.5
31.82
24.13
mg/l
2.03
103
806
99
950
1.18
0.29
6.5
5.7
41.31
40.16
mmol/mol
0.48
94
875
5
71
0.69
0.27
1.8
1.2
—
33.90
—
0
5
0
12
0.00
0.21
0.0
1.0
—
306.67
—
0
6
0
13
0.00
0.21
0.0
5.8
—
3.13
—
0
13
102
992
1.13
0.19
6.3
4.6
6.19
6.01
mmol/l
0.45
96
901
14
120
1.19
0.17
1.6
1.3
—
—
—
0
0
11
96
1.16
0.10
1.6
1.7
—
—
—
0
0
104
1023
1.09
0.09
5.2
4.9
2.64
2.74
mmol/l
0.63
97
940
30
285
1.07
0.07
4.1
3.0
—
—
—
0
0
102
1009
1.05
0.04
5.2
4.4
4.47
4.60
mmol/l
0.69
97
930
101
1005
1.02
0.00
4.7
4.4
1.35
1.45
mmol/l
1.21
95
921
116
1155
1.04
0.00
87.3
20.3
37.16
40.53
%
6.18
110
1084
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
8
83
0.96
0.00
1.6
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
2.00
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
3.06
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
89
1.01
-0.00
5.7
3.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_MYSOSIS_NOS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_MYSOSIS_NOS 4.838 [2.52, 9.31] < 0.001
Birth year 0.991 [0.98, 1.0] 0.043

During the follow-up period (1.1.1998 — 31.12.2019), 86 out of 207 females with AB1_MYSOSIS_NOS died.

Males

Parameter HR [95% CI] p-value
AB1_MYSOSIS_NOS 4.742 [2.8, 8.04] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 94 out of 240 males with AB1_MYSOSIS_NOS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_MYSOSIS_NOS.

N-year risk Females Males
1 0.397% 1.023%
5 2.369% 4.884%
10 6.124% 12.269%
15 11.84% 22.656%
20 19.31% 36.018%

Relationships between endpoints

↥

Index endpoint: AB1_MYSOSIS_NOS – Other mycoses, not elsewhere classified/unspecified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data