info icon

This is a non-core endpoint: only basic statistics are computed.

Smallpox

AB1_SMALLPOS

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B03
  • Hospital discharge: ICD-9 05[0]
  • Hospital discharge: ICD-8 05[0]
  • Cause of death: ICD-10 B03
  • Cause of death: ICD-9 05[0]
  • Cause of death: ICD-8 05[0]

2 out of 7 registries used, show all original rules.

8

4. Check minimum number of events

None

8

5. Include endpoints

None

8

6. Filter based on genotype QC (FinnGen only)

8

Control definitions (FinnGen only)

Control exclude
AB1_VIRAL_SKIN_MUCOUS_MEMBRANE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 107 50 56
Only index persons 84 41 43
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 23.67 26.43 20.46
Only index persons 23.11 26.21 20.16

-FinnGen-

Key figures

All Female Male
Number of individuals 8 5 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 26.37 30.09 -

-FinRegistry-

Age distribution of first events

0102030406070051015202530AgeIndividuals

-FinnGen-

Age distribution of first events

010012345678AgeIndividuals

-FinRegistry-

Year distribution of first events

19701975198019851990199520052022024681012141618202224262830YearIndividuals

-FinnGen-

Year distribution of first events

19702023012345678YearIndividuals

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
0
26
0.00
1.01
0.0
2.9
—
—
—
0
0
0
27
0.00
1.00
0.0
2.0
—
18.33
—
0
21
0
24
0.00
1.00
0.0
3.8
—
31.68
—
0
17
0
21
0.00
0.72
0.0
4.7
—
—
—
0
0
0
21
0.00
0.72
0.0
2.0
—
0.13
—
0
15
0
15
0.00
0.47
0.0
8.3
—
—
—
0
0
0
15
0.00
0.47
0.0
2.5
—
—
—
0
0
0
11
0.00
0.23
0.0
1.7
—
—
—
0
0
0
10
0.00
0.23
0.0
1.3
—
—
—
0
0
0
12
0.00
0.23
0.0
5.3
—
—
—
0
0
0
12
0.00
0.23
0.0
1.7
—
—
—
0
0
0
13
0.00
0.22
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
2.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.8
—
0.83
—
0
6
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
4.0
—
8.49
—
0
6
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
0.23
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
4.2
—
94.74
—
0
5
0
5
0.00
0.00
0.0
2.8
—
1.66
—
0
5
0
5
0.00
0.00
0.0
4.0
—
1.34
—
0
5
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
66.81
—
0
9
8
73
+∞
0.00
8.6
13.4
—
—
—
0
0
0
7
0.00
0.00
0.0
3.7
—
2.67
—
0
7
0
5
0.00
0.00
0.0
1.6
—
10.40
—
0
5
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_SMALLPOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_SMALLPOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: AB1_SMALLPOS – Smallpox

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
1
-
-
-
-
-
9
-
-
-
-
-
-
-
-
0 (0.00)
-
-
7
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
7
-
-
-
-
-
11
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
2
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
0 (0.00)
-
-
6
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
35
-
-
0 (0.00)
-
-
10
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
26
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
3
-
-
0 (0.00)
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
3
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
74
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
27
-
-
0 (0.00)
-
-
3
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
3
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
12
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
1
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
2
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
6
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
2
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
16
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
13
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
8
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
14
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
24
-
-
-
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
-
-
-
1
-
-
-
-
-
6
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
2
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
5
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
2
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
40
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
0 (0.00)
-
-
24
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
3
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
2
-
-
-
-
-
-
-
-
0 (0.00)
-
-
6
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
1
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
21
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
9
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
0 (0.00)
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
5
-
-
0 (0.00)
-
-
68
-
-
-
-
-
-
-
-
-
-
-
1
-
-
0 (0.00)
-
-
-
-
-
0 (0.00)
-
-
1
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
27
-
-
0 (0.00)
-
-
1
-
-
0 (0.00)
-
-
-
-
-
-
-
-
48
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
0 (0.00)
-
-
1
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102
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111
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81
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81
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172
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23
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54
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160
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17
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72
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115
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33
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105
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39
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106
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104
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37
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29
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207
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108
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67
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78
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27 (0.00)
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327
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35 (0.00)
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45
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29 (0.00)
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62
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28 (0.00)
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300
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27 (0.00)
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52
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23 (0.00)
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16
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31 (0.00)
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392
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32 (0.00)
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64
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44 (0.00)
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13
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75 (0.00)
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33
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