Early syphilis

AB1_EARLY_SYPHILIS_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 A51
  • Hospital discharge: ICD-10 A51
  • Hospital discharge: ICD-9 09[1]
  • Hospital discharge: ICD-8 09[1]
  • Cause of death: ICD-10 A51
  • Cause of death: ICD-9 09[1]
  • Cause of death: ICD-8 09[1]

3 out of 7 registries used, show all original rules.

516

4. Check minimum number of events

None

516

5. Include endpoints

None

516

6. Filter based on genotype QC (FinnGen only)

474

Control definitions (FinnGen only)

Control exclude
AB1_SEXUAL_TRANSMISSION

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF13

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 474 154 320
Unadjusted period prevalence (%) 0.12 0.05 0.15
Median age at first event (years) 38.27 30.03 42.24

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
516
Matched controls
5160
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
23.0
262.0
231
176
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
132.7
225.8
114
11
A51.3
ICD-10 Finland
Secondary syphilis of skin and mucous membranes
+∞
222.5
197
*
A51.0
ICD-10 Finland
Primary genital syphilis
+∞
199.3
178
*
WW200
NOMESCO Finland
Immunization
27.7
153.9
110
50
A63.0
ICD-10 Finland
Anogenital (venereal) warts
42.2
143.0
88
25
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
43.4
142.5
87
24
A56.3
ICD-10 Finland
Chlamydial infection of anus and rectum
1296.8
110.7
104
*
A54.6
ICD-10 Finland
Gonococcal infection of anus and rectum
+∞
91.4
85
*
A51.9
ICD-10 Finland
Early syphilis, unspecified
+∞
87.0
81
*
A54.5
ICD-10 Finland
Gonococcal pharyngitis
873.0
78.5
75
*
Y25
ICPC
Fear sexually transm disease male
9.9
73.9
93
112
A54.0
ICD-10 Finland
Gonococcal infection of lower genitourinary tract without periurethral or accessory gland abscess
+∞
66.1
62
*
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
200.5
53.0
54
*
Z29.2
ICD-10 Finland
Other prophylactic chemotherapy
188.2
49.8
51
*
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
76.6
49.2
55
8
A53.9
ICD-10 Finland
Syphilis, unspecified
+∞
48.7
46
*
D06BB04
ATC
podophyllotoxin; topical
6.8
47.9
82
139
09100
ICD-8 Finland
Early syphilis, symptomatic, Primary syphilis, except extragenital chancre
+∞
43.3
41
*
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
16.3
40.3
35
23
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.6
33.1
88
220
A51.5
ICD-10 Finland
Early syphilis, latent
+∞
25.2
24
*
0913A
ICD-9 Finland
Early syphilis, symptomatic, Secondary syphilis of skin or mucous membranes
+∞
24.1
23
*
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
5.0
23.4
53
115
Z3231
NOMESCO Finland
Registered nurse
2.7
23.2
171
799
A56.4
ICD-10 Finland
Chlamydial infection of pharynx
125.6
22.8
24
*
Z2221
NOMESCO Finland
Medical doctor
2.7
22.5
165
768
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
6.3
22.0
38
64
ULA02
NOMESCO Finland
Kolposcopy
4.6
21.7
55
131
Y70
ICPC
Syphilis male
+∞
21.0
20
*
09120
ICD-8 Finland
Early syphilis, symptomatic, Secondary syphilis of skin and mucous membranes
+∞
21.0
20
*
Z25.1
ICD-10 Finland
Need for immunization against influenza
4.8
20.3
48
108
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
103.9
18.7
20
*
Y71
ICPC
Gonorrhoea male
+∞
17.8
17
*
J05AB11
ATC
valaciclovir; oral
2.8
17.4
98
393
J01MA02
ATC
ciprofloxacin; systemic
2.2
17.0
210
1210
B23.0
ICD-10 Finland
Acute HIV infection syndrome
+∞
16.8
16
*
A51.4
ICD-10 Finland
Other secondary syphilis
+∞
15.7
15
*
A55
ICD-10 Finland
Chlamydial lymphogranuloma (venereum)
+∞
15.7
15
*
ZX114
NOMESCO Finland
Intramuscular
11.8
15.4
28
25
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
6.9
15.4
24
36
D06BB10
ATC
imiquimod; topical
4.4
14.9
38
91
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
4.6
14.7
36
83
TAB00
NOMESCO Finland
Lumbar puncture
3.9
13.9
42
114
EB1AA, ,
SPAT
3.4
13.0
50
160
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
12.7
12.7
22
18
Z71.8
ICD-10 Finland
Other specified counselling
2.0
12.5
176
1043
J05AB01
ATC
aciclovir; systemic
2.2
12.0
116
592
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.1
12.0
146
818
A52.1
ICD-10 Finland
Symptomatic neurosyphilis
+∞
11.5
11
*
A52.9
ICD-10 Finland
Late syphilis, unspecified
+∞
11.5
11
*
N48.1
ICD-10 Finland
Balanoposthitis
3.9
10.7
32
86
WX110, ,
SPAT
3.2
10.7
44
147
D11
ICPC
Diarrhoea
2.4
10.5
82
381
WNF00
NOMESCO Finland
Infection source and contact determination
33.3
10.4
13
*
J01AA02
ATC
doxycycline; systemic
2.0
10.3
379
3016
EB1SA, ,
SPAT
3.3
10.3
40
129
J01FA10
ATC
azithromycin; systemic
1.8
10.1
310
2321
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
9.7
112
610
I84
ICD-10 Finland
Hemorrhoids
4.8
9.4
21
45
J01DB01
ATC
cefalexin; oral
2.1
9.1
431
3645
P01AB01
ATC
metronidazole; oral, rectal
1.8
9.0
186
1224
Y99
ICPC
Genital disease male other
19.0
9.0
13
7
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.0
8.8
119
683
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.9
8.8
130
769
D06AX01
ATC
fusidic acid; topical
2.4
8.6
62
277
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
8.6
101
552
Z20.6
ICD-10 Finland
Contact with and exposure to human immunodeficiency virus [HIV]
20.4
8.5
12
6
WX290, ,
SPAT
3.6
8.5
28
81
LEB00
NOMESCO Finland
Biopsy of vagina
8.7
8.4
17
20
A53.0
ICD-10 Finland
Latent syphilis, unspecified as early or late
+∞
8.4
8
*
0910A
ICD-9 Finland
Early syphilis, symptomatic, Genital syphilis (primary)
+∞
8.4
8
*
N06AX11
ATC
mirtazapine; oral
1.8
8.0
174
1155
F43.29
ICD-10 Finland
Adaptation disorder UNS
4.1
7.7
21
53
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.5
7.6
47
196
N05BA04
ATC
oxazepam; oral
1.8
7.6
125
763
A51.1
ICD-10 Finland
Primary anal syphilis
+∞
7.3
7
*
A56.2
ICD-10 Finland
Chlamydial infection of genitourinary tract, unspecified
30.5
7.2
9
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
7.1
203
1446
R4120
NOMESCO Finland
Occupational therapy
2.7
7.0
36
137
U07
ICPC
Urine symptom/complaint other
2.9
6.8
32
116
B37.4
ICD-10 Finland
Candidiasis of other urogenital sites
17.0
6.8
10
6
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.9
6.6
30
106
S29
ICPC
Skin symptom/complaint other
1.9
6.6
86
485
R74
ICPC
Upper respiratory infection acute
1.7
6.5
177
1237
Z01.7
ICD-10 Finland
Laboratory examination
2.0
6.4
77
422
EMB10
NOMESCO Finland
Tonsillectomy
2.5
6.4
39
162
A51.2
ICD-10 Finland
Primary syphilis of other sites
+∞
6.3
6
*
A52.8
ICD-10 Finland
Late syphilis, latent
+∞
6.3
6
*
A03.3
ICD-10 Finland
Shigellosis due to Shigella sonnei
+∞
6.3
6
*
A54.9
ICD-10 Finland
Gonococcal infection, unspecified
+∞
6.3
6
*
A52.3
ICD-10 Finland
Neurosyphilis, unspecified
+∞
6.3
6
*
D01BA02
ATC
terbinafine; oral
1.7
6.2
129
837
N48.8
ICD-10 Finland
Other specified disorders of penis
8.7
6.1
12
14
LDA10
NOMESCO Finland
Curettage of cervix uteri
5.3
6.1
17
33
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.2
6.0
52
252

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
245
79
58.15
307.65
10.7
1.8
8.07
—
titre
—
127
0
163
123
18.91
181.82
5.6
3.8
0.14
0.22
g/l
1.33
140
57
110
36
38.56
172.59
2.6
2.1
32.06
34.06
%
0.34
110
36
104
30
43.17
169.01
2.6
3.2
29.81
44.64
%
2.82
15
18
257
615
7.33
113.28
5.3
1.6
—
—
—
0
0
227
525
6.93
102.15
4.2
1.7
—
—
—
0
0
168
402
5.71
69.92
4.4
1.5
—
—
—
0
0
146
372
5.08
55.35
2.1
2.9
31.59
43.96
u/l
0.51
138
323
235
955
3.68
45.83
8.9
6.2
—
—
—
0
0
205
831
3.43
38.98
3.1
3.2
—
—
—
0
0
58
84
7.65
38.96
1.2
1.1
—
—
—
0
0
254
1283
2.93
31.52
3.6
3.5
14.86
106.64
e6/l
1.93
138
917
221
1041
2.96
31.12
7.2
1.9
—
—
—
0
0
53
93
6.24
29.58
1.2
1.1
—
—
—
0
0
319
2040
2.48
21.72
10.9
6.3
0.19
0.19
e9/l
0.44
296
1824
312
1982
2.45
21.46
11.0
5.9
0.58
0.58
e9/l
0.08
289
1740
312
1982
2.45
21.46
11.0
5.9
0.04
0.04
e9/l
0.94
289
1742
258
1518
2.40
20.95
4.2
5.1
37.82
36.59
g/l
2.57
242
1442
314
2017
2.42
20.82
6.5
6.3
11.92
12.01
umol/l
0.05
300
1919
317
2053
2.41
20.51
11.0
6.1
2.08
1.99
e9/l
0.59
296
1851
342
2304
2.44
20.03
12.4
8.9
3.86
4.13
e9/l
1.42
313
2026
300
1914
2.36
19.84
11.1
5.9
53.33
56.78
%
5.58
288
1833
262
1585
2.33
19.54
3.2
2.9
5.91
5.77
ph
0.33
22
162
295
1878
2.33
19.48
11.6
6.4
8.61
8.56
%
0.14
283
1796
295
1879
2.33
19.45
9.6
6.5
—
—
—
0
0
293
1863
2.33
19.37
11.5
6.0
2.75
2.91
%
0.76
281
1775
301
1943
2.32
19.10
11.3
6.0
32.49
28.42
%
7.28
289
1860
284
1797
2.29
18.79
11.8
6.2
0.74
0.67
%
1.41
272
1712
366
2618
2.37
17.53
5.2
3.7
—
—
—
0
0
192
1063
2.28
17.15
1.8
1.6
1.40
1.53
mmol/l
1.19
183
913
181
988
2.28
16.63
2.5
2.8
—
—
—
0
0
128
603
2.49
16.40
2.0
2.7
0.71
0.84
e6/l
0.28
58
343
57
171
3.62
16.39
1.3
1.4
220.65
226.52
miu/ml
0.04
23
94
182
1011
2.24
15.90
2.6
2.9
0.21
0.37
e6/l
1.38
124
761
274
1798
2.12
15.49
13.5
8.5
0.00
0.00
e9/l
0.44
236
1472
118
570
2.39
14.12
2.1
2.9
2.81
1.31
e6/l
0.56
48
311
230
1455
2.05
13.91
9.2
3.2
37.43
35.02
u/l
0.15
223
1384
282
1940
2.00
13.26
3.3
3.1
0.00
0.01
estimate
0.50
31
344
281
1932
2.00
13.22
3.3
3.1
0.00
0.00
estimate
0.50
34
393
279
1923
1.98
12.93
5.1
4.2
0.00
0.00
estimate
-0.00
34
376
185
1111
2.04
12.65
2.7
3.0
15.01
112.79
e6/l
1.02
128
857
385
2987
2.14
12.64
8.6
7.4
75.26
76.84
u/l
0.34
372
2846
36
110
3.44
10.05
2.1
1.1
—
—
—
0
0
305
2281
1.82
9.91
5.3
5.0
6.30
6.70
mmol/l
3.51
297
2131
89
447
2.20
9.47
1.8
1.6
—
—
—
0
0
133
808
1.87
8.26
1.9
1.7
—
—
—
0
0
304
2369
1.69
7.66
3.8
3.7
382.00
2040.56
e6/l
—
5
36
35
125
2.93
7.59
2.0
3.5
—
—
—
0
0
18
41
4.51
7.48
2.1
1.7
—
—
—
0
0
471
4205
2.38
7.43
13.5
12.2
25.22
22.94
mg/l
0.73
377
3287
47
203
2.45
7.05
3.7
3.5
—
—
—
0
0
30
104
3.00
6.86
1.5
1.3
—
—
—
0
0
27
92
3.04
6.36
2.3
3.4
—
—
—
0
0
26
88
3.06
6.20
1.8
1.4
—
—
—
0
0
348
2888
1.63
6.18
4.1
3.6
10.44
9.92
mm/h
0.33
335
2697
93
554
1.83
6.00
2.5
2.1
—
—
—
0
0
82
475
1.86
5.78
1.6
1.5
—
—
—
0
0
32
127
2.62
5.73
2.0
2.8
1.14
1.35
mg/l
1.93
24
120
16
43
3.81
5.40
3.9
2.4
1.79
1.31
e9/l
1.55
16
38
47
233
2.12
5.14
1.1
1.2
—
—
—
0
0
114
752
1.66
5.10
2.5
2.4
3.35
5.56
e6/l
1.16
103
678
48
243
2.08
4.98
1.8
2.4
—
—
—
0
0
132
1809
0.64
4.72
2.6
2.5
—
—
—
0
0
421
3767
1.64
4.53
5.8
4.9
37.57
39.27
mmol/mol
0.98
402
3579
162
1192
1.52
4.50
2.2
2.2
—
—
—
0
0
138
986
1.55
4.37
4.4
4.5
—
—
—
0
0
15
38
4.03
4.33
2.2
1.4
—
—
—
0
0
49
267
1.92
4.16
1.8
1.8
41.65
36.25
nmol/l
0.70
49
259
52
290
1.88
4.13
1.8
2.4
—
—
—
0
0
55
314
1.84
4.06
1.8
2.3
—
—
—
0
0
55
315
1.84
4.02
1.8
2.3
—
—
—
0
0
7
7
10.11
4.02
3.0
1.4
—
—
—
0
0
108
744
1.57
3.99
1.5
1.5
20.77
20.45
nmol/l
0.09
96
646
198
1550
1.45
3.94
5.2
6.6
1.20
1.21
mmol/l
0.86
182
1446
54
310
1.83
3.92
1.8
2.4
—
—
—
0
0
139
1016
1.50
3.91
3.0
4.0
7.39
7.40
ph
2.23
20
191
13
33
4.01
3.82
2.7
2.5
945.85
667.56
e6/l
0.90
13
27
86
567
1.62
3.81
2.3
2.4
14.70
14.20
nmol/l
0.24
79
529
435
3974
1.60
3.73
5.1
3.9
5.89
5.91
mmol/l
0.07
408
3707
23
99
2.38
3.55
1.9
1.3
23.65
16.67
e6/l
0.17
17
76
23
99
2.38
3.55
1.9
1.4
474.65
929.91
e6/l
0.24
17
78
155
1180
1.45
3.51
2.9
3.4
8.28
8.73
mmol/l
0.53
135
1028
422
3850
1.53
3.41
19.7
14.9
334.87
334.98
g/l
0.10
422
3829
52
310
1.75
3.35
1.8
2.1
—
—
—
0
0
102
726
1.50
3.22
2.5
2.6
590.54
566.71
mosm/kgh2o
0.40
85
625
8
15
5.40
3.20
4.9
2.1
—
—
—
0
0
20
85
2.41
3.19
2.1
2.6
1.56
2.09
mmol/l
0.71
15
55
176
1394
1.40
3.14
2.2
1.9
—
—
—
0
0
78
527
1.57
3.12
1.3
1.3
490.67
400.41
titre
0.31
15
97
15
57
2.68
2.99
1.0
1.2
—
—
—
0
0
479
4543
1.76
2.82
13.1
9.3
30.19
31.17
u/l
0.34
472
4413
144
1120
1.40
2.82
3.0
3.4
2.36
2.35
mmol/l
0.27
124
1014
5
6
8.40
2.75
1.4
1.3
—
—
—
0
0
7
14
5.05
2.73
1.3
1.4
29.14
27.14
umol/l
—
7
14
7
15
4.71
2.60
1.3
1.6
—
—
—
0
0
15
62
2.46
2.56
2.0
2.4
—
—
—
0
0
162
1305
1.35
2.52
2.0
1.8
98.46
95.55
pmol/l
0.32
91
704
29
160
1.86
2.45
4.0
10.5
—
—
—
0
0
31
178
1.79
2.32
1.5
1.6
8.48
6.32
u/l
0.47
26
153
24
127
1.93
2.30
1.3
1.1
—
—
—
0
0
64
445
1.50
2.27
1.3
1.2
—
—
—
0
0
5
9
5.60
2.22
3.4
1.4
—
—
—
0
0
444
4184
1.44
2.17
14.2
13.7
3.93
3.98
mmol/l
2.78
432
4080
88
1151
0.72
2.16
3.0
2.6
—
—
—
0
0
9
30
3.03
2.15
2.2
2.8
38466.67
39683.33
ug/l
—
9
30
203
1725
1.29
2.10
5.4
7.3
1.20
1.21
mmol/l
0.23
171
1498
33
200
1.69
2.07
1.2
2.2
—
—
—
0
0
34
209
1.67
2.03
1.9
1.9
228.76
221.82
pmol/l
0.13
34
198
10
38
2.66
2.01
1.3
1.8
—
—
—
0
0
13
57
2.31
1.99
1.5
1.5
199.18
176.55
pmol/l
0.44
13
57
78
579
1.41
1.99
3.1
2.9
2.43
2.43
mmol/l
0.22
65
510
50
343
1.51
1.91
1.9
2.5
0.22
0.22
g/l
0.24
45
318
107
842
1.34
1.91
1.4
1.3
2.67
2.44
g/l
0.64
59
579
33
205
1.65
1.91
1.5
1.3
—
—
—
0
0
9
34
2.68
1.87
1.6
1.2
1.52
1.51
g/l
—
9
34
124
1000
1.32
1.87
2.4
2.4
3073.19
6848.81
umol/l
0.62
113
905
8
28
2.89
1.87
1.0
1.0
—
—
—
0
0
440
4166
1.38
1.85
14.1
13.7
139.32
139.64
mmol/l
2.32
433
4074
106
842
1.33
1.78
2.7
2.6
—
—
—
0
0
9
36
2.53
1.74
1.6
1.3
1.07
0.95
g/l
—
9
36
8
30
2.69
1.73
1.0
1.3
—
—
—
0
0
7
24
2.94
1.72
1.4
1.5
—
—
—
0
0
102
813
1.32
1.67
2.2
1.9
2.86
2.93
mg/l
0.11
89
706
7
25
2.82
1.65
1.4
1.5
—
—
—
0
0
21
121
1.77
1.61
1.4
1.3
—
—
—
0
0
7
26
2.71
1.58
1.0
1.0
—
—
—
0
0
496
4827
1.71
1.57
22.6
17.4
252.58
247.64
e9/l
0.95
488
4732
50
360
1.43
1.53
2.5
2.6
1.62
1.77
%
0.60
45
328
0
44
0.00
1.52
0.0
2.5
—
106.09
—
0
44
0
44
0.00
1.52
0.0
2.5
—
4.04
—
0
44
0
44
0.00
1.52
0.0
2.5
—
—
—
0
0
318
2924
1.23
1.47
3.4
3.4
14.53
14.64
pmol/l
0.33
292
2686
30
196
1.56
1.46
1.1
1.1
—
14.20
—
0
5
15
80
1.90
1.46
2.1
2.5
—
—
—
0
0
62
469
1.37
1.44
7.0
7.8
105.63
103.86
mmol/l
3.88
62
469
496
4837
1.66
1.41
22.6
17.3
4.58
4.67
e12/l
3.63
484
4735
10
46
2.20
1.40
1.6
2.8
—
—
—
0
0
9
40
2.27
1.40
1.1
1.2
40.82
52.41
mg/l
—
9
29
0
39
0.00
1.34
0.0
1.5
—
76.49
—
0
39
57
432
1.36
1.32
7.2
9.8
0.48
1.16
mmol/l
0.71
49
357
495
4832
1.60
1.31
22.8
17.4
41.57
42.55
%
0.48
485
4582
6
24
2.52
1.30
1.7
2.9
953.50
751.00
u/ml
—
6
24
6
24
2.52
1.30
1.0
1.3
140.50
158.33
nmol/l
—
6
24
18
107
1.71
1.27
1.1
1.1
—
—
—
0
0
385
3636
1.23
1.27
4.2
4.0
1.78
2.18
mu/l
0.65
361
3381
69
543
1.31
1.26
2.6
2.6
100.28
143.54
ug/g
1.05
53
452
203
1807
1.20
1.25
2.6
2.5
—
—
—
0
0
495
4836
1.58
1.25
22.6
17.3
6.82
6.67
e9/l
0.83
483
4734
39
280
1.42
1.25
1.5
1.4
—
—
—
0
0
18
108
1.69
1.24
1.1
1.1
—
—
—
0
0
46
341
1.38
1.23
7.4
8.3
1.50
1.39
mmol/l
0.36
46
335
39
282
1.41
1.20
1.5
3.2
4.27
8.00
e9/l
0.99
33
256
43
317
1.39
1.19
7.6
9.7
—
—
—
0
0
85
693
1.27
1.19
3.2
3.4
1454.91
707.46
ng/l
0.24
65
494
446
4291
1.29
1.19
5.6
4.3
2.85
2.86
mmol/l
0.06
423
4041
6
26
2.32
1.19
1.5
1.4
16100.00
31021.06
e6/l
—
6
16
104
870
1.24
1.17
3.3
3.3
1.02
1.02
kg/l
—
7
119
60
469
1.32
1.15
2.1
2.7
9.16
9.08
umol/l
0.01
49
412
8
39
2.07
1.15
2.4
1.3
—
—
—
0
0
8
39
2.07
1.15
1.1
1.1
279.50
253.44
mg/l
—
8
32
166
1460
1.20
1.15
2.4
2.2
77.40
73.89
nmol/l
0.69
146
1338
7
30
2.35
1.12
1.4
1.4
3324.57
2481.05
e6/l
—
7
21
21
136
1.57
1.10
1.6
2.2
94.16
645.02
ug/l
1.03
21
130
7
32
2.20
1.08
1.6
2.2
27.43
33.41
pg
—
7
32
7
32
2.20
1.08
1.6
1.9
—
—
—
0
0
23
153
1.53
1.08
1.3
1.3
—
—
—
0
0
61
485
1.29
1.05
1.7
2.4
27.21
25.31
%
0.34
54
434
20
130
1.56
1.04
1.6
2.2
0.70
1.84
ug/l
0.81
14
116
34
250
1.39
0.98
1.1
1.1
—
—
—
0
0
38
285
1.36
0.98
2.7
3.4
—
—
—
0
0
33
242
1.39
0.97
4.2
6.8
—
—
—
0
0
0
32
0.00
0.95
0.0
1.7
—
6.29
—
0
23
0
32
0.00
0.95
0.0
5.7
—
—
—
0
0
0
32
0.00
0.95
0.0
2.8
—
—
—
0
0
7
37
1.90
0.94
2.3
2.7
0.87
0.91
nmol/l
—
7
28
439
4242
1.23
0.94
5.2
4.0
4.65
4.69
mmol/l
0.44
417
4018
6
27
2.24
0.93
1.8
1.3
—
—
—
0
0
10
56
1.80
0.88
1.1
1.5
—
—
—
0
0
36
465
0.76
0.85
2.1
1.6
—
—
—
0
0
58
705
0.80
0.85
1.3
1.3
—
—
—
0
0
6
31
1.95
0.84
1.0
2.5
—
—
—
0
0
9
150
0.59
0.80
5.4
8.6
2.39
1.63
%
—
9
136
86
997
0.84
0.80
3.6
3.4
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
—
—
0
0
0
27
0.00
0.77
0.0
1.2
—
—
—
0
0
114
1005
1.17
0.76
2.9
3.5
1311.10
243.42
mg/l
0.65
72
702
6
34
1.77
0.76
2.0
2.2
—
—
—
0
0
9
53
1.71
0.75
1.2
1.1
—
—
—
0
0
180
1644
1.15
0.75
2.6
2.6
141.04
139.44
ug/l
0.03
172
1545
9
54
1.68
0.75
1.7
1.4
—
—
—
0
0
10
60
1.68
0.72
1.6
1.5
—
—
—
0
0
12
76
1.59
0.72
1.1
1.0
3.00
11.12
u/ml
—
5
45
25
186
1.36
0.71
1.2
1.2
—
—
—
0
0
22
162
1.37
0.67
2.4
2.5
262.90
3522.90
u/l
—
6
61
5
28
1.79
0.66
1.0
1.0
—
—
—
0
0
105
934
1.16
0.64
1.3
1.2
0.61
1.34
u/ml
2.34
28
269
5
29
1.73
0.64
2.4
1.8
—
—
—
0
0
434
4227
1.17
0.62
5.3
3.9
1.33
1.37
mmol/l
1.43
408
3986
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.1
—
34.77
—
0
16
10
149
0.66
0.57
5.0
8.6
3.69
0.90
%
—
10
135
6
36
1.67
0.57
1.2
1.1
—
—
—
0
0
11
73
1.52
0.56
1.1
1.1
10.06
0.80
u/ml
—
6
29
8
55
1.46
0.56
2.0
1.6
—
—
—
0
0
10
65
1.55
0.56
1.1
1.6
—
—
—
0
0
6
37
1.63
0.55
1.0
1.1
—
—
—
0
0
101
906
1.14
0.55
1.8
1.7
1.01
1.03
mg/l
0.02
75
666
43
512
0.83
0.55
1.5
1.4
—
—
—
0
0
419
4084
1.14
0.53
4.5
3.6
1.36
1.36
mmol/l
0.01
388
3844
31
251
1.25
0.52
2.1
2.7
65.77
72.30
e9/l
0.59
23
186
113
1026
1.13
0.52
2.5
2.4
0.58
0.70
ug/l
1.12
81
553
72
635
1.16
0.51
1.4
1.2
40.13
27.34
iu/ml
0.41
20
195
6
41
1.47
0.50
1.0
1.4
—
—
—
0
0
68
601
1.15
0.47
1.3
1.2
10.52
7.56
u/ml
0.12
36
263
11
77
1.44
0.46
3.2
3.4
3.67
4.19
e9/l
0.46
11
77
133
1231
1.11
0.45
1.4
1.5
—
—
—
0
0
11
152
0.72
0.44
3.2
3.1
—
—
—
0
0
112
1027
1.12
0.44
3.6
3.3
0.00
0.01
estimate
0.69
30
362
18
230
0.77
0.44
3.3
3.2
121.89
132.73
g/l
1.18
18
223
10
69
1.46
0.44
2.2
2.3
—
—
—
0
0
14
104
1.36
0.43
1.0
1.2
344.11
249.41
u/ml
—
9
64
11
78
1.42
0.43
1.5
1.2
5.00
4.74
u/ml
—
6
38
11
78
1.42
0.43
3.1
3.8
53.91
55.99
%
0.24
11
78
136
1461
0.91
0.43
3.3
3.2
21.12
35.87
ng/l
1.93
79
909
13
173
0.75
0.42
4.0
3.4
25.50
25.00
mmol/l
0.41
13
166
19
149
1.29
0.42
2.7
4.7
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
197.51
—
0
15
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
7.09
—
0
18
74
669
1.12
0.38
1.4
1.6
436.34
11735127.04
pmol/l
0.50
64
588
5
36
1.39
0.38
1.2
1.3
—
—
—
0
0
67
603
1.13
0.37
1.8
1.4
—
—
—
0
0
133
1244
1.09
0.37
2.7
2.8
60.55
61.31
u/l
0.04
121
1166
9
71
1.27
0.36
1.1
1.7
—
—
—
0
0
9
121
0.74
0.35
1.2
1.1
—
—
—
0
0
11
144
0.76
0.33
1.5
1.7
—
—
—
0
0
114
1064
1.09
0.33
3.3
4.0
16.28
9.67
mg/mmol
0.37
72
729
6
89
0.67
0.33
7.2
12.2
104.33
104.97
mmol/l
—
6
77
6
89
0.67
0.33
7.2
12.2
12.67
11.71
mmol/l
—
6
77
454
4480
1.11
0.30
12.2
11.1
—
—
—
0
0
15
185
0.81
0.30
1.1
1.1
—
—
—
0
0
8
67
1.20
0.26
1.1
1.2
10.29
16.70
u/l
—
8
60
5
72
0.69
0.26
1.0
1.1
—
—
—
0
0
174
1668
1.07
0.26
10.8
10.9
1.14
1.18
inr
0.41
42
521
18
151
1.20
0.25
1.4
1.2
0.52
1.92
u/ml
—
5
15
20
232
0.86
0.23
2.5
3.2
5.23
5.17
kpa
0.12
20
224
179
1725
1.06
0.22
4.3
3.7
2.95
1.81
ug/l
0.63
165
1575
5
40
1.25
0.22
2.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
1.33
—
0
5
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
8.9
—
—
—
0
0
35
316
1.12
0.21
1.1
1.1
—
—
—
0
0
11
89
1.24
0.21
1.4
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
72.69
—
0
13
16
187
0.85
0.20
1.8
2.6
1.45
1.42
%
0.04
16
187
12
99
1.22
0.19
1.1
1.4
—
—
—
0
0
14
165
0.84
0.19
2.2
3.3
—
—
—
0
0
11
90
1.23
0.19
1.2
1.1
2.87
1.89
u/ml
—
6
48
34
370
0.91
0.16
2.2
2.0
323.83
373.44
nmol/l
0.78
29
345
18
158
1.14
0.16
1.3
1.7
—
—
—
0
0
16
183
0.87
0.16
1.8
2.5
0.76
0.70
%
0.18
16
183
8
71
1.13
0.16
1.1
2.9
—
—
—
0
0
48
449
1.08
0.15
1.3
1.3
—
—
—
0
0
13
149
0.87
0.13
1.5
1.6
—
—
—
0
0
11
127
0.86
0.12
3.2
2.8
—
—
—
0
0
11
126
0.87
0.11
1.1
2.2
9.17
11.82
mg/l
0.87
11
118
23
249
0.92
0.10
1.9
1.4
—
—
—
0
0
39
370
1.06
0.09
9.2
10.8
126.21
124.80
g/l
0.17
39
358
6
57
1.05
0.08
2.8
2.1
—
—
—
0
0
5
63
0.79
0.08
1.2
1.1
—
—
—
0
0
6
70
0.86
0.07
1.0
1.1
—
—
—
0
0
6
75
0.80
0.07
1.5
1.3
—
—
—
0
0
7
80
0.87
0.07
1.0
1.1
—
92.49
—
0
21
9
88
1.02
0.07
1.6
1.5
—
—
—
0
0
9
88
1.02
0.07
1.6
1.5
—
—
—
0
0
281
2785
1.02
0.06
3.4
3.4
—
—
—
0
0
29
304
0.95
0.06
1.9
2.2
7.16
9.08
ug/l
0.46
24
276
29
304
0.95
0.06
4.3
4.2
0.46
0.44
%
0.03
13
103
17
159
1.07
0.05
2.0
2.1
—
—
—
0
0
25
238
1.05
0.05
1.2
1.6
—
—
—
0
0
51
496
1.03
0.04
1.1
1.3
—
—
—
0
0
32
308
1.04
0.04
4.6
4.5
0.00
0.13
%
2.61
16
99
23
222
1.04
0.02
2.2
2.4
—
—
—
0
0
55
541
1.02
0.02
1.6
1.6
1172.85
1213.66
nmol/l
0.13
41
427
33
338
0.97
0.01
3.7
3.2
—
—
—
0
0
22
214
1.03
0.00
12.3
12.9
—
—
—
0
0
26
254
1.02
0.00
1.2
1.2
42.39
116.84
iu/ml
—
7
102
31
304
1.02
0.00
3.8
4.6
—
—
—
0
0
37
367
1.01
0.00
1.6
1.4
—
—
—
0
0
29
292
0.99
0.00
4.6
4.6
0.00
0.23
%
1.18
12
82
33
331
1.00
0.00
4.5
4.3
1.09
0.86
%
0.19
17
123
320
3197
1.00
0.00
3.1
3.1
47.21
48.91
u/l
0.15
301
3042
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
8
83
0.96
0.00
2.3
3.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
9.7
—
—
—
0
0
9
90
1.00
-0.00
3.3
2.2
25.61
25.08
mmol/l
—
9
90
0
7
0.00
-0.00
0.0
1.1
—
87.34
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
85
0.94
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
18.49
—
0
9
0
7
0.00
-0.00
0.0
1.1
—
0.03
—
0
7
0
7
0.00
-0.00
0.0
2.9
—
—
—
0
0
7
72
0.97
-0.00
3.0
1.9
9.24
8.42
kpa
—
7
72
0
9
0.00
-0.00
0.0
6.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
9
89
1.01
-0.00
1.7
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.2
—
2205.67
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
62
0.97
-0.00
1.3
2.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
2.13
—
0
7
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
1.20
—
0
9
5
55
0.91
-0.00
2.2
2.8
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_EARLY_SYPHILIS_WIDE – Early syphilis

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).