No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
445 |
4. Check minimum number of eventsNone |
445 |
5. Include endpointsNone |
445 |
6. Filter based on genotype QC (FinnGen only) |
406 |
Control definitions (FinnGen only)
- Control exclude
- AB1_SEXUAL_TRANSMISSION
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Early syphilis
based on the number of shared cases.
Similar with more cases:
- Early syphilis
- Syphilis
- Syphilis
- Infections with a predominantly sexual mode of transmission
- Infections with a predominantly sexual mode of transmission
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2515 | 815 | 1643 |
| Only index persons | 2222 | 742 | 1480 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.02 | 0.05 |
| Only index persons | 0.05 | 0.03 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 36.88 | 33.67 | 38.63 |
| Only index persons | 36.48 | 32.83 | 38.31 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 406 | 107 | 299 |
| Unadjusted period prevalence (%) | 0.11 | 0.04 | 0.14 |
| Median age at first event (years) | 39.57 | 32.21 | 42.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 445
- Matched controls
- 4450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
30.7
277.4
218
135
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
151.1
226.5
113
10
A51.0
ICD-10 Finland
Primary genital syphilis
+∞
192.0
170
*
A51.3
ICD-10 Finland
Secondary syphilis of skin and mucous membranes
+∞
154.4
139
*
WW200
NOMESCO Finland
Immunization
30.0
154.3
108
47
A56.0
ICD-10 Finland
Chlamydial infection of lower genitourinary tract
69.4
145.0
80
14
A56.3
ICD-10 Finland
Chlamydial infection of anus and rectum
1350.2
111.5
104
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
39.9
104.3
65
19
A54.6
ICD-10 Finland
Gonococcal infection of anus and rectum
+∞
90.8
84
*
A51.9
ICD-10 Finland
Early syphilis, unspecified
+∞
87.4
81
*
A54.5
ICD-10 Finland
Gonococcal pharyngitis
896.8
78.9
75
*
Y25
ICPC
Fear sexually transm disease male
11.3
77.2
89
96
A54.0
ICD-10 Finland
Gonococcal infection of lower genitourinary tract without periurethral or accessory gland abscess
+∞
64.1
60
*
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
200.0
52.1
53
*
Z29.2
ICD-10 Finland
Other prophylactic chemotherapy
191.4
50.0
51
*
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
87.2
49.2
54
7
A53.9
ICD-10 Finland
Syphilis, unspecified
+∞
46.7
44
*
09100
ICD-8 Finland
Early syphilis, symptomatic, Primary syphilis, except extragenital chancre
+∞
43.4
41
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
5.3
36.7
83
183
A51.5
ICD-10 Finland
Early syphilis, latent
+∞
25.2
24
*
A56.4
ICD-10 Finland
Chlamydial infection of pharynx
+∞
25.2
24
*
0913A
ICD-9 Finland
Early syphilis, symptomatic, Secondary syphilis of skin or mucous membranes
+∞
24.2
23
*
Z3231
NOMESCO Finland
Registered nurse
2.8
22.8
155
703
Z25.1
ICD-10 Finland
Need for immunization against influenza
5.3
21.8
46
94
Z2221
NOMESCO Finland
Medical doctor
2.8
21.1
147
672
09120
ICD-8 Finland
Early syphilis, symptomatic, Secondary syphilis of skin and mucous membranes
+∞
21.0
20
*
A60.0
ICD-10 Finland
Herpesviral infection of genitalia and urogenital tract
17.8
19.4
30
18
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
104.5
18.7
20
*
J01MA02
ATC
ciprofloxacin; systemic
2.4
17.9
195
1088
Y70
ICPC
Syphilis male
+∞
17.8
17
*
Y71
ICPC
Gonorrhoea male
+∞
17.8
17
*
J05AB11
ATC
valaciclovir; oral
3.0
17.5
89
340
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
5.2
17.4
37
76
D06BB04
ATC
podophyllotoxin; topical
4.4
16.8
45
112
B23.0
ICD-10 Finland
Acute HIV infection syndrome
+∞
16.8
16
*
ZX114
NOMESCO Finland
Intramuscular
15.0
16.5
27
19
A55
ICD-10 Finland
Chlamydial lymphogranuloma (venereum)
+∞
15.7
15
*
Z20.2
ICD-10 Finland
Contact with and exposure to infections with a predominantly sexual mode of transmission
6.0
15.6
28
49
ULA02
NOMESCO Finland
Kolposcopy
4.5
14.2
36
86
TAB00
NOMESCO Finland
Lumbar puncture
4.1
13.8
39
101
A51.4
ICD-10 Finland
Other secondary syphilis
+∞
13.6
13
*
EB1AA, ,
SPAT
3.5
12.6
46
143
Z71.8
ICD-10 Finland
Other specified counselling
2.1
12.1
150
854
D11
ICPC
Diarrhoea
2.7
11.8
73
306
A52.1
ICD-10 Finland
Symptomatic neurosyphilis
+∞
11.5
11
*
WX110, ,
SPAT
3.4
11.4
42
131
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
2.2
11.1
124
676
EB1SA, ,
SPAT
3.5
10.7
37
111
A52.9
ICD-10 Finland
Late syphilis, unspecified
+∞
10.5
10
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
4.7
10.4
24
53
J05AB01
ATC
aciclovir; systemic
2.2
10.3
100
513
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
12.6
9.9
17
14
N48.1
ICD-10 Finland
Balanoposthitis
3.8
9.7
30
83
J01FA10
ATC
azithromycin; systemic
1.9
9.7
265
1945
WNF00
NOMESCO Finland
Infection source and contact determination
30.7
9.4
12
*
I84
ICD-10 Finland
Hemorrhoids
5.1
9.4
20
41
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
3.0
9.3
43
154
J01AA02
ATC
doxycycline; systemic
2.0
9.1
336
2695
Y99
ICPC
Genital disease male other
19.1
9.0
13
7
Z20.6
ICD-10 Finland
Contact with and exposure to human immunodeficiency virus [HIV]
24.6
8.9
12
5
J01DB01
ATC
cefalexin; oral
2.2
8.9
375
3139
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
2.0
8.7
105
583
F43.29
ICD-10 Finland
Adaptation disorder UNS
4.8
8.4
19
41
A53.0
ICD-10 Finland
Latent syphilis, unspecified as early or late
+∞
8.4
8
*
0910A
ICD-9 Finland
Early syphilis, symptomatic, Genital syphilis (primary)
+∞
8.4
8
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
8.3
95
517
WX290, ,
SPAT
3.8
7.8
24
66
EMB10
NOMESCO Finland
Tonsillectomy
3.0
7.8
35
123
J35.0
ICD-10 Finland
Chronic tonsillitis
3.2
7.7
31
102
LDA10
NOMESCO Finland
Curettage of cervix uteri
7.3
7.5
17
24
U07
ICPC
Urine symptom/complaint other
3.2
7.4
29
94
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
7.4
86
469
A51.1
ICD-10 Finland
Primary anal syphilis
+∞
7.3
7
*
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.3
7.3
28
90
A56.2
ICD-10 Finland
Chlamydial infection of genitourinary tract, unspecified
30.5
7.2
9
*
B37.4
ICD-10 Finland
Candidiasis of other urogenital sites
20.4
7.2
10
5
LEB00
NOMESCO Finland
Biopsy of vagina
9.0
7.1
14
16
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.9
7.0
109
657
N06AX11
ATC
mirtazapine; oral
1.8
6.8
149
993
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
6.7
6.4
15
23
N48.8
ICD-10 Finland
Other specified disorders of penis
9.4
6.3
12
13
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
6.3
184
1321
N05BA04
ATC
oxazepam; oral
1.8
6.3
106
652
A52.3
ICD-10 Finland
Neurosyphilis, unspecified
+∞
6.3
6
*
A54.9
ICD-10 Finland
Gonococcal infection, unspecified
+∞
6.3
6
*
A52.8
ICD-10 Finland
Late syphilis, latent
+∞
6.3
6
*
A03.3
ICD-10 Finland
Shigellosis due to Shigella sonnei
+∞
6.3
6
*
P01AB01
ATC
metronidazole; oral, rectal
1.7
6.2
154
1059
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
205
131
28.16
255.70
10.4
1.5
—
—
—
0
0
209
161
23.59
236.51
10.6
1.6
—
—
—
0
0
125
22
78.62
229.21
14.5
8.4
1514.47
111.13
u/ml
—
72
8
108
31
45.68
176.63
2.6
2.2
31.95
33.57
%
0.23
108
31
103
26
51.25
173.92
2.6
3.2
28.51
41.90
%
2.19
14
15
133
5
377.83
138.85
3.8
1.8
—
—
—
0
0
220
435
9.02
119.96
7.9
1.8
—
—
—
0
0
228
483
8.63
116.14
8.9
1.8
—
—
—
0
0
140
328
5.77
59.67
2.1
3.0
31.92
45.85
u/l
0.51
135
284
45
41
12.10
43.09
1.1
1.1
—
—
—
0
0
309
2002
2.78
21.95
12.3
9.3
3.82
4.13
e9/l
1.60
283
1753
51
118
4.75
20.96
1.3
1.4
245.48
229.09
miu/ml
0.09
19
64
269
1654
2.58
20.83
11.5
6.1
52.97
57.05
%
6.77
261
1584
236
1365
2.55
20.82
4.3
5.3
37.89
36.49
g/l
2.87
222
1296
264
1612
2.57
20.70
11.9
6.3
2.72
2.93
%
1.04
256
1537
270
1676
2.55
20.29
11.7
6.3
32.74
28.09
%
8.25
262
1605
179
940
2.51
19.00
1.9
1.7
1.40
1.55
mmol/l
1.41
171
801
279
1804
2.47
18.50
6.8
6.5
12.13
12.26
umol/l
0.07
269
1720
42
97
4.68
17.25
2.6
1.5
—
—
—
0
0
27
41
6.95
17.22
1.0
1.1
—
—
—
0
0
116
526
2.63
16.41
2.0
2.7
0.74
0.88
e6/l
0.26
50
296
163
869
2.38
16.25
2.5
2.9
0.22
0.38
e6/l
1.20
109
652
253
1644
2.25
15.51
3.3
3.0
0.00
0.00
estimate
0.50
24
314
252
1642
2.23
15.25
5.2
4.2
0.00
0.00
estimate
-0.00
24
300
253
1655
2.23
15.11
3.3
3.1
0.00
0.01
estimate
0.50
21
274
210
1284
2.20
14.75
9.7
3.3
37.84
35.76
u/l
0.12
204
1222
107
497
2.52
14.21
1.9
2.9
2.61
1.18
e6/l
0.45
41
268
190
1137
2.17
13.87
2.7
3.1
—
—
—
0
0
164
959
2.12
12.42
2.6
3.0
15.95
116.36
e6/l
0.86
112
737
341
2629
2.27
12.14
8.8
7.8
76.22
77.64
u/l
0.27
329
2503
43
140
3.29
10.92
1.6
1.4
—
—
—
0
0
20
36
5.77
10.79
1.9
1.8
—
—
—
0
0
403
3450
2.78
9.65
14.7
11.2
89.69
87.55
ml/min/173m2
1.33
340
2886
270
2002
1.89
9.46
5.4
5.2
6.36
6.76
mmol/l
3.08
264
1897
409
3612
2.64
7.61
13.6
12.8
26.70
23.54
mg/l
1.01
332
2826
41
174
2.49
6.43
1.9
1.3
—
—
—
0
0
26
91
2.97
5.88
1.4
1.1
—
—
—
0
0
26
91
2.97
5.88
1.4
1.1
—
—
—
0
0
53
264
2.14
5.77
2.7
2.7
72.70
70.75
ml/min/173m2
0.14
27
114
303
2514
1.64
5.52
4.0
3.7
10.98
10.19
mm/h
0.48
292
2346
29
113
2.68
5.41
1.8
2.8
1.16
1.36
mg/l
1.49
21
106
14
29
4.95
4.85
1.1
2.6
—
—
—
0
0
375
3338
1.78
4.75
6.1
5.1
37.65
39.58
mmol/mol
1.01
359
3173
46
241
2.01
4.40
1.7
1.9
40.41
36.35
nmol/l
0.52
46
235
9
14
6.54
4.00
3.4
2.0
—
—
—
0
0
7
8
8.87
3.78
1.0
1.0
—
—
—
0
0
11
24
4.67
3.76
4.1
2.4
—
—
—
0
0
175
1363
1.47
3.69
5.5
6.9
1.20
1.21
mmol/l
0.83
160
1274
21
85
2.54
3.68
2.0
1.5
537.87
221.05
e6/l
0.41
15
64
21
85
2.54
3.68
2.0
1.4
26.60
18.66
e6/l
0.17
15
62
80
525
1.64
3.67
2.3
2.3
14.98
14.34
nmol/l
0.31
74
490
139
1053
1.47
3.32
2.9
3.5
8.49
8.68
mmol/l
0.17
119
913
15
54
2.84
3.28
1.1
1.0
1.83
1.18
u/ml
—
6
25
94
659
1.54
3.25
1.5
1.5
21.46
20.42
nmol/l
0.31
85
574
378
3469
1.60
3.12
5.3
4.1
5.95
5.95
mmol/l
0.04
355
3239
106
770
1.49
3.10
2.1
2.4
—
—
—
0
0
7
13
5.45
2.88
1.3
1.4
29.14
27.46
umol/l
—
7
13
32
175
1.89
2.76
1.0
1.0
—
—
—
0
0
24
120
2.06
2.66
1.3
1.6
0.03
0.06
iu/ml
0.40
11
23
95
696
1.46
2.64
1.9
1.5
—
—
—
0
0
6
11
5.51
2.55
6.2
1.9
—
—
—
0
0
6
11
5.51
2.55
2.3
2.1
—
—
—
0
0
9
27
3.38
2.40
1.6
1.3
1.52
1.53
g/l
—
9
27
415
3952
1.74
2.30
13.5
9.6
31.22
31.92
u/l
0.19
410
3845
143
1153
1.35
2.27
2.1
1.8
96.40
95.63
pmol/l
0.07
79
624
9
29
3.15
2.23
1.6
1.4
1.07
0.95
g/l
—
9
29
13
54
2.45
2.21
1.5
1.5
199.18
170.84
pmol/l
0.61
13
54
12
48
2.54
2.20
1.6
1.1
—
—
—
0
0
18
87
2.11
2.20
2.8
1.7
—
—
—
0
0
8
24
3.37
2.19
1.3
1.1
—
—
—
0
0
71
513
1.46
2.12
3.3
3.0
2.43
2.44
mmol/l
0.17
58
451
16
76
2.15
2.05
1.0
1.1
—
—
—
0
0
124
995
1.34
2.00
3.2
3.5
2.36
2.35
mmol/l
0.29
105
898
8
27
3.00
1.94
2.3
2.8
38812.50
40433.33
ug/l
—
8
27
179
1521
1.30
1.91
5.7
7.6
1.20
1.21
mmol/l
0.25
150
1329
14
65
2.19
1.90
1.7
1.6
—
—
—
0
0
31
190
1.68
1.90
1.8
1.9
239.81
221.83
pmol/l
0.38
31
182
89
684
1.38
1.89
2.2
2.0
2.89
2.98
mg/l
0.13
78
596
387
3658
1.44
1.86
14.3
14.4
3.93
3.99
mmol/l
3.28
377
3578
6
17
3.56
1.84
1.2
1.0
—
—
—
0
0
287
2601
1.29
1.81
3.7
3.1
—
—
—
0
0
8
30
2.70
1.73
1.3
1.2
—
—
—
0
0
49
344
1.48
1.71
1.9
1.7
—
—
—
0
0
45
312
1.49
1.67
2.0
2.5
0.22
0.22
g/l
0.23
40
289
7
25
2.83
1.65
1.0
1.0
—
—
—
0
0
44
312
1.46
1.48
7.7
8.8
1.52
1.41
mmol/l
0.33
44
307
9
38
2.40
1.46
2.9
1.8
—
—
—
0
0
5
16
3.15
1.44
1.0
1.2
49.20
15.82
u/l
—
5
11
33
224
1.51
1.38
1.5
1.6
—
—
—
0
0
23
143
1.64
1.38
1.6
1.5
6.64
6.29
u/l
0.06
18
123
109
903
1.27
1.37
2.4
2.5
3462.74
6626.58
umol/l
0.42
99
813
54
404
1.38
1.37
7.1
10.1
0.51
1.24
mmol/l
0.73
46
337
48
352
1.41
1.36
1.9
1.8
—
—
—
0
0
20
120
1.70
1.36
2.2
2.8
—
—
—
0
0
5
17
2.96
1.36
1.0
1.2
192.00
81.33
u/l
—
5
12
45
327
1.42
1.35
4.0
3.0
—
—
—
0
0
12
61
1.99
1.34
2.4
1.8
—
—
—
0
0
427
4157
1.67
1.33
23.0
18.0
251.13
245.52
e9/l
1.02
419
4076
17
99
1.75
1.29
1.2
1.1
—
—
—
0
0
270
2482
1.22
1.28
3.4
3.3
14.48
14.67
pmol/l
0.61
249
2275
427
4162
1.64
1.25
23.3
18.1
41.83
42.89
%
0.44
418
3944
144
1244
1.23
1.25
2.4
2.3
79.34
74.20
nmol/l
1.03
127
1139
80
646
1.29
1.23
1.8
2.1
1.57
1.49
%
0.30
70
589
11
56
1.99
1.23
1.4
1.4
—
—
—
0
0
11
56
1.99
1.23
1.4
1.4
—
—
—
0
0
154
1345
1.22
1.20
2.6
2.6
152.65
156.47
ug/l
0.07
149
1263
427
4166
1.62
1.19
23.0
17.9
4.59
4.69
e12/l
3.72
415
4078
6
26
2.32
1.19
1.5
1.4
16100.00
31021.06
e6/l
—
6
16
91
754
1.26
1.14
1.4
1.2
0.55
1.36
u/ml
2.32
22
228
56
435
1.33
1.14
7.6
8.1
105.41
103.79
mmol/l
3.19
56
435
7
30
2.35
1.12
1.3
1.1
—
—
—
0
0
5
21
2.40
1.09
2.6
2.6
—
—
—
0
0
7
33
2.14
1.06
1.1
1.1
283.43
262.19
mg/l
—
7
26
7
33
2.14
1.06
1.1
1.1
—
—
—
0
0
77
636
1.25
1.00
3.3
3.4
1557.12
664.40
ng/l
0.26
59
467
5
23
2.19
0.98
1.8
3.0
1030.00
762.39
u/ml
—
5
23
7
36
1.96
0.97
3.4
3.9
—
—
—
0
0
168
1506
1.19
0.97
2.7
2.5
—
—
—
0
0
0
31
0.00
0.96
0.0
1.5
—
—
—
0
0
24
166
1.47
0.96
1.4
1.5
—
—
—
0
0
6
27
2.24
0.94
1.7
1.0
—
—
—
0
0
6
27
2.24
0.94
1.7
1.0
—
—
—
0
0
329
3127
1.20
0.93
4.2
3.9
1.83
2.26
mu/l
0.59
307
2905
13
79
1.66
0.89
2.7
1.4
—
—
—
0
0
117
1328
0.84
0.88
3.2
3.3
22.50
37.34
ng/l
1.66
68
856
8
44
1.83
0.86
1.3
1.2
—
—
—
0
0
6
32
1.89
0.82
1.2
1.1
—
—
—
0
0
6
32
1.89
0.82
1.2
1.1
—
—
—
0
0
6
32
1.89
0.82
1.2
1.1
—
—
—
0
0
6
32
1.89
0.82
1.2
1.1
—
—
—
0
0
6
32
1.89
0.82
1.2
1.1
—
—
—
0
0
388
3762
1.24
0.80
6.0
4.4
2.86
2.86
mmol/l
0.02
367
3540
16
106
1.53
0.80
1.2
1.2
—
—
—
0
0
19
131
1.47
0.79
1.6
2.3
99.38
659.79
ug/l
1.00
19
125
11
66
1.68
0.79
2.9
3.8
—
3497.13
—
0
8
8
48
1.68
0.79
3.4
1.6
—
—
—
0
0
0
26
0.00
0.78
0.0
1.8
—
3.23
—
0
13
60
498
1.24
0.77
1.9
1.8
—
—
—
0
0
9
53
1.71
0.76
2.9
1.5
—
—
—
0
0
52
428
1.24
0.72
1.7
2.5
27.29
24.80
%
0.42
47
382
51
419
1.25
0.72
2.0
2.8
10.00
8.74
umol/l
0.13
42
375
7
40
1.76
0.71
1.1
1.3
—
—
—
0
0
5
26
1.93
0.71
1.2
1.2
—
—
—
0
0
9
58
1.56
0.70
2.8
1.7
—
—
—
0
0
9
58
1.56
0.70
2.8
1.7
—
—
—
0
0
7
42
1.68
0.68
3.3
1.6
—
—
—
0
0
7
42
1.68
0.68
3.3
1.6
—
—
—
0
0
5
27
1.86
0.68
1.4
1.3
32.40
46.48
u/l
—
5
22
5
28
1.79
0.66
2.0
2.5
—
—
—
0
0
88
771
1.18
0.66
1.8
1.8
1.04
1.08
mg/l
0.08
63
587
10
63
1.60
0.62
3.4
3.7
3.47
4.39
e9/l
—
10
63
0
21
0.00
0.60
0.0
1.2
—
1.03
—
0
8
11
162
0.67
0.59
4.5
3.5
25.29
24.95
mmol/l
0.26
11
157
0
22
0.00
0.59
0.0
1.1
—
113.35
—
0
17
10
64
1.58
0.59
3.3
4.1
52.80
56.73
%
—
10
64
11
73
1.52
0.56
1.2
1.1
—
—
—
0
0
13
183
0.70
0.56
4.5
2.5
0.65
0.13
e6/l
0.54
13
175
381
3716
1.18
0.55
5.5
4.1
4.65
4.70
mmol/l
0.46
361
3518
25
196
1.29
0.54
1.3
1.4
—
—
—
0
0
16
215
0.73
0.54
3.5
3.3
122.44
132.68
g/l
0.95
16
209
9
62
1.46
0.53
1.1
1.1
—
—
—
0
0
9
62
1.46
0.53
1.2
1.3
—
—
—
0
0
6
39
1.55
0.53
1.8
1.5
—
—
—
0
0
14
101
1.40
0.50
1.4
1.9
—
—
—
0
0
13
93
1.41
0.48
1.0
1.1
—
—
—
0
0
12
85
1.42
0.47
2.4
1.7
—
—
—
0
0
15
196
0.76
0.43
2.5
3.4
1.91
1.79
mmol/l
—
10
149
8
56
1.44
0.42
1.0
1.1
—
—
—
0
0
12
87
1.39
0.42
2.4
1.7
—
—
—
0
0
5
33
1.52
0.41
1.0
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
3.8
—
75.61
—
0
16
12
88
1.37
0.40
8.1
6.1
—
264.64
—
0
14
61
544
1.14
0.39
1.4
1.2
43.16
29.04
iu/ml
0.41
18
168
9
67
1.35
0.38
3.1
1.6
—
—
—
0
0
106
982
1.10
0.37
2.5
2.5
0.58
0.69
ug/l
0.93
78
525
269
2780
0.92
0.37
3.1
3.2
48.64
51.30
u/l
0.21
254
2638
9
121
0.74
0.35
1.4
1.7
—
—
—
0
0
5
80
0.62
0.35
1.6
1.6
—
—
—
0
0
366
3588
1.11
0.35
4.7
3.7
1.40
1.39
mmol/l
0.15
337
3376
93
858
1.11
0.35
3.6
3.3
0.00
0.01
estimate
0.69
20
289
11
82
1.35
0.34
1.0
1.3
—
—
—
0
0
6
45
1.34
0.34
1.3
1.4
—
—
—
0
0
14
109
1.29
0.34
1.4
2.1
—
—
—
0
0
104
970
1.09
0.32
3.4
4.0
17.31
9.06
mg/mmol
0.44
65
658
7
53
1.33
0.31
1.4
1.7
—
—
—
0
0
376
3702
1.10
0.28
5.6
4.1
1.31
1.36
mmol/l
1.87
352
3488
8
63
1.27
0.28
1.1
1.2
10.29
17.06
u/l
—
8
56
32
363
0.87
0.27
4.5
4.1
27.48
29.72
%
0.41
21
263
33
372
0.88
0.26
4.7
7.0
—
—
—
0
0
5
74
0.67
0.26
1.6
1.3
—
—
—
0
0
126
1325
0.93
0.25
3.3
3.0
—
—
—
0
0
9
73
1.24
0.25
1.2
1.4
—
—
—
0
0
18
212
0.84
0.24
2.7
3.3
5.29
5.17
kpa
0.22
18
205
16
188
0.85
0.21
1.3
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
0.45
—
0
6
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
10
0.00
0.21
0.0
1.1
—
110.80
—
0
10
22
192
1.15
0.21
1.3
1.1
30.45
94.05
iu/ml
—
6
78
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
9.66
—
0
13
0
14
0.00
0.20
0.0
3.8
—
—
—
0
0
0
14
0.00
0.20
0.0
3.8
—
—
—
0
0
15
176
0.85
0.20
1.9
2.6
1.44
1.43
%
0.01
15
176
6
51
1.18
0.19
1.3
1.1
—
—
—
0
0
6
51
1.18
0.19
1.3
1.1
—
—
—
0
0
26
289
0.89
0.18
1.8
2.3
7.13
9.21
ug/l
0.47
21
263
55
514
1.08
0.18
1.2
1.2
13.73
7.93
u/ml
0.19
27
225
15
172
0.87
0.16
1.9
2.5
0.75
0.70
%
0.16
15
172
9
83
1.09
0.14
3.3
2.1
25.61
25.08
mmol/l
—
9
83
10
84
1.19
0.14
1.7
1.4
—
—
—
0
0
44
466
0.94
0.12
2.0
1.8
—
—
—
0
0
127
1304
0.96
0.11
3.2
3.4
22.56
21.13
%
0.37
49
486
10
115
0.87
0.10
1.1
2.1
10.01
11.44
mg/l
—
10
108
11
125
0.88
0.10
1.5
1.9
—
—
—
0
0
109
1120
0.96
0.10
2.8
2.8
62.87
61.60
u/l
0.05
99
1055
28
262
1.07
0.09
1.3
1.4
—
—
—
0
0
168
1650
1.03
0.09
4.4
3.7
3.07
1.80
ug/l
0.66
154
1507
47
489
0.96
0.07
1.6
1.7
1080.18
1216.55
nmol/l
0.54
33
388
154
1515
1.03
0.07
10.2
11.6
1.15
1.21
inr
0.45
35
458
81
825
0.98
0.04
2.7
3.1
1068.75
966.63
ng/l
0.16
69
691
61
599
1.02
0.03
1.4
1.7
420.72
438.74
pmol/l
0.25
54
524
0
9
0.00
0.00
0.0
4.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
52.54
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
71
0.99
-0.00
1.4
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
1.29
—
0
8
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
58
0.86
-0.00
1.4
1.4
—
—
—
0
0
6
67
0.89
-0.00
1.5
1.4
—
—
—
0
0
6
59
1.02
-0.00
1.5
1.6
—
—
—
0
0
7
69
1.01
-0.00
2.1
1.7
—
—
—
0
0
7
71
0.99
-0.00
1.0
1.1
—
23.19
—
0
17
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
35
350
1.00
-0.00
9.4
11.0
126.34
124.87
g/l
0.16
35
338
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
41.60
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.0
—
0.40
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_EARLY_SYPHILIS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_EARLY_SYPHILIS | 1.498 [1.19, 1.88] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 80 out of 997 males with AB1_EARLY_SYPHILIS died.
Mortality risk
Mortality risk for people of age
years, who have AB1_EARLY_SYPHILIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.299% |
| 5 | No data | 1.658% |
| 10 | No data | 4.176% |
| 15 | No data | 7.743% |
| 20 | No data | 12.609% |
Relationships between endpoints
↥Index endpoint: AB1_EARLY_SYPHILIS – Early syphilis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data