No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1580 |
4. Check minimum number of eventsNone |
1580 |
5. Include endpointsNone |
1580 |
6. Filter based on genotype QC (FinnGen only) |
1580 |
Control definitions (FinnGen only)
- Control exclude
- L12_PAPULOSQUAMOUS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L40
- Name in latin
- Pustulosis palmaris et plantaris
Similar endpoints
↥List of similar endpoints to
Pustulosis palmaris et plantaris
based on the number of shared cases.
Similar with more cases:
- Pustular psoriasis
- Psoriasis
- Papulosquamous disorders
- Autoimmune diseases related-to ILD
- Autoimmune diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9805 | 6825 | 2953 |
| Only index persons | 9263 | 6578 | 2685 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.20 | 0.08 |
| Only index persons | 0.20 | 0.24 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 51.84 | 53.06 | 49.05 |
| Only index persons | 51.55 | 52.89 | 48.26 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1580 | 1137 | 443 |
| Unadjusted period prevalence (%) | 0.33 | 0.39 | 0.20 |
| Median age at first event (years) | 53.31 | 53.39 | 53.11 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1444
- Matched controls
- 14440
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D05BB02
ATC
acitretin; oral
109.6
323.0
375
46
D07AD01
ATC
clobetasol; topical
25.0
323.0
1015
1248
D05AX52
ATC
calcipotriol, combinations; topical
36.4
323.0
439
171
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
9014.0
323.0
1381
25
L40.0
ICD-10 Finland
Psoriasis vulgaris
120.6
265.5
282
29
D07XC01
ATC
betamethasone, combinations; topical
10.6
239.1
524
738
E0000UV
ATC
NA
6.7
239.0
1021
3834
D05AX02
ATC
calcipotriol; topical
36.9
234.0
303
103
D07AC01
ATC
betamethasone; topical
6.4
231.4
931
3185
D07AC13
ATC
mometasone; topical
5.7
198.7
816
2683
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
297.5
158.9
159
6
D07BC01
ATC
betamethasone and antiseptics; topical
6.1
141.0
445
978
E000001
ATC
NA
4.9
136.4
562
1668
E000003
ATC
NA
11.9
135.8
264
267
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
7.1
134.0
367
662
WXQ12
NOMESCO Finland
Psoralen - Ultraviolet A therapy with local sensitivisation
215.8
116.4
119
6
D05AX03
ATC
calcitriol; topical
64.8
112.3
130
22
L40.5
ICD-10 Finland
Arthropathic psoriasis
178.2
111.0
115
7
L30.9
ICD-10 Finland
Dermatitis, unspecified
4.4
108.2
473
1428
D02AE01
ATC
carbamide; topical
7.8
105.5
262
398
TQW80
NOMESCO Finland
Local dermatologic skincare
11.8
77.6
148
138
E000002
ATC
NA
4.2
67.9
290
811
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.7
67.1
253
626
M07.3
ICD-10 Finland
Other psoriatic arthropathies
101.9
62.4
68
7
L40.9
ICD-10 Finland
Psoriasis, unspecified
48.6
61.1
74
16
L40.8
ICD-10 Finland
Other psoriasis
69.0
57.7
66
10
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.8
55.6
199
461
E000006
ATC
NA
4.7
55.5
204
486
D07CC01
ATC
betamethasone and antibiotics; topical
3.4
55.0
308
1064
L30.3
ICD-10 Finland
Infective dermatitis
7.9
54.2
129
177
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.5
50.3
264
864
H02AB06
ATC
prednisolone; systemic
2.3
49.3
784
4930
J01AA07
ATC
tetracycline; systemic
2.9
46.6
331
1336
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.2
44.6
266
950
319
Kela drug reimbursment
Adalimumab, brodalumab, certolizumab pegol, etanercept, guselkumab, infliximab, ixekizumab, risankizumab, sekukinumab and ustekinumab (skin psoriasis)
450.9
44.5
44
*
L04AB04
ATC
adalimumab; parenteral
9.9
44.3
91
97
J01AA04
ATC
lymecycline; systemic
3.0
44.2
288
1092
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
6.0
43.9
127
228
A07EC01
ATC
sulfasalazine; oral, rectal
3.8
43.1
198
576
6961D
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PUSTULOSIS PALMOPLANTARIS]
+∞
42.9
41
*
L04AD01
ATC
ciclosporin; systemic
10.6
42.8
85
85
68693
ICD-8 Finland
Other local infections of skin and subcutaneous tissue, Pustulosis palmo-plantaris
+∞
41.9
40
*
L04AA01
ATC
[U] ciclosporin; systemic
11.4
40.9
78
72
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
7.1
40.6
103
155
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
6.8
40.3
105
164
E000004
ATC
NA
7.7
36.1
86
118
N07BA03
ATC
varenicline; oral
4.3
35.9
142
359
D07AB02
ATC
hydrocortisone butyrate; topical
2.2
35.3
464
2555
XQ802
NOMESCO Finland
Epicutan test
4.8
35.3
123
274
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.7
34.7
162
475
D09AB01
ATC
zinc bandage without supplements; topical
9.9
33.8
69
73
WXQ27
NOMESCO Finland
UVB narrow spectrum light therapy
15.1
32.4
54
37
J01DB01
ATC
cefalexin; oral
2.3
31.4
1212
10088
L43.0
ICD-10 Finland
Hypertrophic lichen planus
163.4
30.8
32
*
D07AB08
ATC
desonide; topical
2.9
30.1
201
763
S91
ICPC
Psoriasis
37.9
29.4
37
10
L40
ICD-10 Finland
Psoriasis
15.1
28.4
47
32
D07AC14
ATC
methylprednisolone aceponate; topical
4.4
28.3
106
254
M13.9
ICD-10 Finland
Arthritis, unspecified
3.3
28.2
151
492
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.1
28.1
374
2032
L04AC10
ATC
secukinumab; parenteral
79.2
27.8
31
*
J01FF01
ATC
clindamycin; systemic
2.0
27.4
436
2547
N02AX02
ATC
tramadol; systemic, rectal
1.9
27.1
636
4288
E000007
ATC
NA
3.5
25.3
125
382
XQ848
NOMESCO Finland
Dermatological photography
5.9
25.1
72
128
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.7
25.1
190
774
K05.31
ICD-10 Finland
Periodontitis pronounced
2.6
23.9
183
750
L04AA13
ATC
leflunomide; oral
5.2
23.0
72
143
D02AX
ATC
Other emollients and protectives
4.7
22.6
78
172
S29
ICPC
Skin symptom/complaint other
2.2
22.6
262
1324
Z72.0
ICD-10 Finland
Tobacco use
5.8
22.5
65
117
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
22.4
351
2013
A10BA02
ATC
metformin; oral
1.9
21.4
376
2242
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
21.3
364
2151
S21
ICPC
Skin texture symptom/complaint
2.4
21.2
199
907
J01DA01
ATC
[U] cefalexin; systemic
1.7
20.7
924
7355
L40.1
ICD-10 Finland
Generalized pustular psoriasis
212.9
20.6
21
*
L04AB01
ATC
etanercept; parenteral
7.2
20.5
50
72
EBA00
NOMESCO Finland
Extraction of tooth
1.8
20.3
474
3107
R03AC02
ATC
salbutamol; inhalant
1.7
19.9
763
5784
T90
ICPC
Diabetes non-insulin dependent
1.9
19.9
327
1897
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.8
19.7
138
533
L30.0
ICD-10 Finland
Nummular dermatitis
4.4
19.4
71
167
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
18.7
592
4223
L04AB06
ATC
golimumab; parenteral
10.2
17.9
35
35
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
17.7
17
*
D05AA
ATC
Tars
21.2
17.3
25
12
S99
ICPC
Skin disease other
6.3
17.1
45
73
L43.8
ICD-10 Finland
Other lichen planus
16.1
17.0
27
17
D11AH04
ATC
alitretinoin; oral
91.1
16.6
18
*
P01AB01
ATC
metronidazole; oral, rectal
1.6
16.2
598
4398
L88
ICPC
Rheumatoid/seropositive arthritis
3.5
16.1
76
225
SPAT1263
SPAT
Sampling
1.6
16.1
585
4285
M073, L403
ICD-10 Finland
NA
+∞
15.6
15
*
B35.3
ICD-10 Finland
Tinea pedis
3.6
15.4
71
207
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.8
15.4
102
383
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
15.3
663
5052
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
15.3
364
2361
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
3.6
15.0
67
190
R06AE07
ATC
cetirizine; oral
1.6
14.9
634
4800
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.0
14.9
212
1157
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.6
14.9
68
197
L04AC13
ATC
ixekizumab; parenteral
80.9
14.6
16
*
P17
ICPC
Tobacco abuse
5.5
14.4
42
78
SPAT1262
SPAT
Handing over of treatment supplies
1.9
14.4
247
1440
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
14.4
292
1800
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.4
14.3
125
548
A10BK03
ATC
empagliflozin; oral
2.6
14.2
109
446
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
14.1
539
3954
134
Kela drug reimbursment
General erythroderma
42.9
14.1
17
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
14.0
252
1489
A02BC02
ATC
pantoprazole; systemic
1.5
14.0
907
7533
M54.5
ICD-10 Finland
Low back pain
1.6
14.0
460
3251
L40.4
ICD-10 Finland
Guttate psoriasis
53.9
13.8
16
*
L04AA11
ATC
[U] etanercept; parenteral
20.2
13.8
20
10
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.2
13.7
142
677
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
4.6
13.7
47
105
R03BB04
ATC
tiotropium bromide; inhalant
2.2
13.7
138
648
377
Kela drug reimbursment
Apremilast and dimethyl fumarate (psoriasis)
75.8
13.6
15
*
D01BA02
ATC
terbinafine; oral; topical
1.7
13.5
341
2239
L04AC05
ATC
ustekinumab; parenteral
34.4
13.5
17
5
L04AX01
ATC
azathioprine; systemic
2.9
13.3
82
295
A46
ICD-10 Finland
Erysipelas
2.0
12.6
183
999
L03
ICPC
Low back symptom/complaint
1.7
12.6
330
2185
D05AX05
ATC
tazarotene; topical
70.5
12.6
14
*
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.1
12.6
140
688
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
12.5
488
3576
L40.2
ICD-10 Finland
Acrodermatitis continua
+∞
12.5
12
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
12.5
558
4219
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
12.4
174
938
A10BH01
ATC
sitagliptin; oral
2.2
12.4
130
623
L17
ICPC
Foot/toe symptom/complaint
1.6
12.0
332
2225
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
11.8
514
3851
WZA10
NOMESCO Finland
Long statement of health and health related matters
5.1
11.7
36
72
M25.5
ICD-10 Finland
Pain in joint
1.6
11.6
409
2911
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
11.6
275
1764
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.9
11.5
180
1010
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
11.5
387
2722
L43.3
ICD-10 Finland
Subacute (active) lichen planus
+∞
11.5
11
*
D07AC03
ATC
desoximetasone; topical
4.6
11.3
38
84
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.3
11.3
103
463
D07AA02
ATC
hydrocortisone; topical
1.9
11.3
185
1057
N06AA09
ATC
amitriptyline; systemic
2.0
11.2
149
789
L20.0
ICD-10 Finland
Besnier prurigo
2.4
11.0
93
402
M03BX02
ATC
tizanidine; oral
1.5
11.0
893
7581
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
10.9
373
2632
N02BE01
ATC
paracetamol; systemic, rectal
1.6
10.9
1204
10924
L08.0
ICD-10 Finland
Pyoderma
7.9
10.9
24
31
WX110
NOMESCO Finland
Local anesthesy
1.5
10.8
938
8052
L73.2
ICD-10 Finland
Hidradenitis suppurativa
6.8
10.7
26
39
L04AA32
ATC
apremilast; oral
60.4
10.6
12
*
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
5.8
10.6
29
51
C10AA01
ATC
simvastatin; oral
1.5
10.5
511
3893
L30.1
ICD-10 Finland
Dyshidrosis [pompholyx]
10.1
10.5
20
20
R02
ICPC
Shortness of breath/dyspnoea
1.9
10.4
155
855
R95
ICPC
Chron obstructive pulmonary disease
3.8
10.4
43
116
D01AE15
ATC
terbinafine; topical
2.2
10.3
101
467
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
4.8
10.3
33
70
S97
ICPC
Chronic ulcer skin
2.6
10.3
76
307
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.3
10.2
49
150
SPAT1301
SPAT
No procedures
1.5
10.1
404
2947
SPAT1312
SPAT
General health counselling
1.5
10.1
410
3003
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
5.0
10.1
31
63
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.3
9.9
94
431
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.0
9.7
130
689
L43.9
ICD-10 Finland
Lichen planus, unspecified
7.4
9.7
22
30
SPAT1310
SPAT
Counselling related to known health issue
1.5
9.7
416
3079
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
9.5
374
2711
XQ800
NOMESCO Finland
Prick test
2.0
9.5
118
606
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
9.4
242
1579
L04AC16
ATC
guselkumab; systemic
100.6
9.4
10
*
L30.4
ICD-10 Finland
Erythema intertrigo
5.2
9.4
28
55
69619
ICD-8 Finland
Psoriasis and similar disorders, Psoriasis alia sive NUD (vulgaris)
+∞
9.4
9
*
6961A
ICD-9 Finland
Psoriasis and similar disorders, Other psoriasis[PSORIASIS VULGARIS]
+∞
9.4
9
*
N05CD07
ATC
temazepam; oral
1.8
9.4
157
904
NH3EA
NOMESCO Finland
Feet X-ray examination with load
3.6
9.4
40
112
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.4
9.3
76
325
N05AH04
ATC
quetiapine; oral
1.7
9.2
215
1369
WZA90
NOMESCO Finland
Other doctors statement
1.6
9.2
302
2099
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.5
9.1
69
283
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.0
9.1
113
583
H02AB07
ATC
prednisone; oral
1.7
9.1
199
1244
S76
ICPC
Skin infection other
2.4
9.1
74
314
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
9.0
1268
11776
N03AX16
ATC
pregabalin; oral
1.5
9.0
321
2274
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.4
9.0
75
325
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
8.9
325
2316
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.9
8.9
51
177
R06AE09
ATC
levocetirizine; oral
1.7
8.8
207
1319
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
8.7
369
2712
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
8.7
334
2401
WX290
NOMESCO Finland
Other blockade of nerve
1.4
8.7
572
4581
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
8.6
376
2783
M10.9
ICD-10 Finland
Gout, unspecified
2.3
8.6
77
344
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
8.6
952
8354
P01BA02
ATC
hydroxychloroquine; oral
1.9
8.5
126
694
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.9
8.5
50
178
M79.6
ICD-10 Finland
Pain in limb
1.4
8.4
473
3672
M07.2*L40.5
ICD-10 Finland
Psoriatic spondylitis
+∞
8.3
8
*
M07.0
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
8.3
8
*
L04AB05
ATC
certolizumab pegol; parenteral
9.5
8.3
16
17
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.9
8.2
119
652
N06AX11
ATC
mirtazapine; oral
1.4
8.2
424
3236
L16
ICPC
Ankle symptom/complaint
1.8
8.2
133
756
K50.0
ICD-10 Finland
Crohn disease of small intestine
4.0
8.2
31
79
R4180
NOMESCO Finland
Podiatric therapy
5.4
8.1
23
43
S18
ICPC
Laceration/cut
1.4
8.1
519
4121
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
8.1
695
5808
WQ021
NOMESCO Finland
NA
33.5
8.1
10
*
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
3.1
8.0
41
133
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.4
8.0
37
112
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
7.9
94
477
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.0
7.9
94
477
S01
ICPC
Pain/tenderness of skin
2.6
7.9
56
223
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
7.9
307
2208
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.4
7.9
62
262
L30.8
ICD-10 Finland
Other specified dermatitis
3.1
7.8
40
131
WQ020
NOMESCO Finland
NA
45.2
7.7
9
*
K50.9
ICD-10 Finland
Crohn disease, unspecified
4.1
7.7
28
69
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
7.7
435
3373
S10
ICPC
Boil/carbuncle
2.2
7.6
74
346
M01AB05
ATC
diclofenac; systemic, rectal
1.4
7.6
911
8010
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
8.9
7.5
15
17
D01AC02
ATC
miconazole; topical
2.0
7.5
99
521
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.4
7.5
487
3865
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
7.5
152
928
WQ031
NOMESCO Finland
NA
80.5
7.4
8
*
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
5.3
7.4
21
40
A10AE04
ATC
insulin glargine; parenteral
1.9
7.4
110
611
-1
NOMESCO Finland
NA
1.4
7.4
426
3312
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.3
7.3
63
276
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
7.3
89
455
A02BC01
ATC
omeprazole; systemic
1.4
7.3
346
2588
L14
ICPC
Leg/thigh symptom/complaint
2.0
7.3
97
514
SPAT1260
SPAT
Consultation of another employee
1.6
7.3
224
1528
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
7.2
140
846
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.0
7.2
39
133
SPAT1283
SPAT
Restricted health certificate
1.6
7.2
219
1492
N05BA01
ATC
diazepam; systemic, rectal
1.6
7.2
181
1177
WXQ10
NOMESCO Finland
Psoralen - Ultraviolet A therapy with systemic sensitivisation
30.2
7.1
9
*
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.3
7.1
60
263
S87
ICPC
Dermatitis/atopic eczema
3.1
7.1
36
117
J01FA06
ATC
roxithromycin; oral
1.4
7.1
542
4410
M54.6
ICD-10 Finland
Pain in thoracic spine
2.0
7.1
92
485
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
7.0
170
1095
N05AH03
ATC
olanzapine; systemic
2.1
7.0
78
387
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.6
6.9
168
1081
L23.8
ICD-10 Finland
Allergic contact dermatitis due to other agents
5.5
6.9
19
35
M01AH01
ATC
celecoxib; oral (coxibs)
1.5
6.9
242
1700
H02AB04
ATC
methylprednisolone; systemic
1.6
6.9
194
1298
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.8
6.8
111
634
EBA30
NOMESCO Finland
Excision of root of tooth
2.1
6.8
73
357
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.8
668
5647
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
5.1
6.8
20
40
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
6.8
149
930
SPAT1153
SPAT
Removal of sutures
1.4
6.8
387
2993
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
6.8
105
592
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
0.5
6.7
49
966
N05CF01
ATC
zopiclone; oral
1.4
6.7
403
3141
J01AA02
ATC
doxycycline; systemic
1.4
6.7
1077
9814
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
2.9
6.7
39
138
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
6.7
515
4184
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.2
6.7
62
284
M01AH05
ATC
etoricoxib; oral
1.3
6.7
806
7018
N05AA02
ATC
levomepromazine; systemic
2.3
6.7
59
263
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
6.7
140
865
N03AX12
ATC
gabapentin; oral
1.6
6.6
196
1325
EKA10
NOMESCO Finland
Biopsy of cheek
3.5
6.6
29
85
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
1.7
6.6
123
734
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
2.7
6.6
43
164
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.6
628
5274
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.6
6.6
153
972
N06AX21
ATC
duloxetine; oral
1.6
6.5
150
951
L23.9
ICD-10 Finland
Allergic contact dermatitis, unspecified cause
4.8
6.5
20
42
H01
ICPC
Ear pain/earache
1.7
6.5
125
751
N05BB01
ATC
hydroxyzine; systemic
1.9
6.5
87
464
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
6.4
733
6312
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.4
733
6313
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.2
6.4
65
309
N05BA04
ATC
oxazepam; oral
1.4
6.4
316
2377
S04
ICPC
Lump/swelling localized
1.8
6.4
109
631
A10BJ06
ATC
semaglutide; parenteral
2.5
6.4
47
193
A02BC03
ATC
lansoprazole; oral
1.4
6.4
375
2911
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
6.4
544
4488
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.3
132
813
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
6.3
842
7415
M01CB03
ATC
auranofin; oral
5.5
6.3
17
31
C07AB07
ATC
bisoprolol; oral
1.3
6.3
545
4502
N05AH02
ATC
clozapine; systemic
3.1
6.2
32
106
L85.1
ICD-10 Finland
Acquired keratosis [keratoderma] palmaris et plantaris
26.8
6.2
8
*
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
6.2
162
1063
N05AB03
ATC
perphenazine; systemic, rectal
2.3
6.2
56
254
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
6.1
88
480
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
3.4
6.1
27
80
L20
ICPC
Joint symptom/complaint NOS
2.4
6.1
50
216
D07CB01
ATC
triamcinolone and antibiotics; topical
2.9
6.1
33
114
SPAT1008
SPAT
Photography of fundus of the eye or interpretation of photograph
2.3
6.1
50
218
S02
ICPC
Pruritus
2.5
6.0
43
173
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
6.0
87
477
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1126
7665
2.63
65.74
12.6
9.0
4.4
4.0
e9/l
12.21
1018
6733
135
362
3.98
44.67
1.6
1.5
0.0
0.1
iu/ml
1.23
23
68
40
28
14.63
44.31
1.5
1.3
9.7
8.7
ug/l
0.51
40
28
1267
10306
2.16
32.42
9.8
7.4
79.0
77.5
u/l
0.51
1197
9711
1226
9975
2.02
29.49
6.9
3.9
15.6
11.9
mm/h
12.53
1147
9249
585
3925
1.78
25.08
3.5
3.1
7.1
7.3
mmol/l
0.57
473
3338
100
334
3.13
23.50
1.6
1.3
—
—
—
0
0
573
3907
1.73
22.67
4.5
3.9
8.8
8.6
mg/mmol
0.05
349
2390
79
240
3.41
21.65
4.0
3.7
55.7
57.7
%
0.70
79
240
835
6405
1.64
20.42
4.3
3.5
0.0
0.0
estimate
0.00
172
1167
840
6454
1.64
20.39
5.7
4.8
0.0
0.0
estimate
0.50
179
1180
846
6518
1.64
20.26
4.4
3.5
0.0
0.0
estimate
1.08
170
1152
46
102
4.62
19.45
1.7
1.4
26.2
35.2
%
0.70
29
66
378
2375
1.78
19.42
1.4
1.3
11.5
12.4
u/ml
0.10
134
954
828
6397
1.62
19.20
6.6
6.6
1.2
1.2
mmol/l
0.26
702
5417
86
302
2.95
18.53
2.0
1.7
12591.5
12711.1
e6/l
0.01
65
224
732
5534
1.60
18.23
4.9
4.7
35.1
35.9
g/l
3.33
675
5163
487
3346
1.66
17.81
3.0
2.5
1123.3
4777.0
umol/l
3.17
412
2914
385
2491
1.72
17.62
1.4
1.3
31.9
35.0
iu/ml
0.17
107
804
754
5826
1.56
16.53
5.8
5.9
1.2
1.2
mmol/l
0.38
690
5280
52
144
3.70
16.41
1.7
1.5
53.8
60.4
%
0.47
33
99
731
5633
1.55
16.06
2.7
2.3
74.7
77.8
nmol/l
2.43
668
5076
521
3742
1.59
15.45
1.9
1.7
1.6
1.4
mmol/l
5.44
426
3173
24
36
6.75
15.32
1.6
2.2
6.8
9.3
mg/l
1.37
19
29
533
3875
1.57
14.87
2.3
2.1
201.0
218.7
u/l
0.18
487
3649
481
3421
1.58
14.74
3.1
2.9
0.5
0.5
e6/l
0.22
370
2555
853
6901
1.51
14.33
5.9
6.2
9.3
10.9
umol/l
5.80
804
6546
379
2582
1.62
13.77
2.5
2.5
6.4
6.6
e6/l
0.07
331
2264
1445
13330
1.98
13.16
19.6
13.1
20.7
22.1
mg/l
1.01
1260
10430
660
5163
1.48
12.46
2.1
1.9
94.6
97.0
pmol/l
0.70
365
2594
470
3434
1.52
12.36
4.8
3.9
0.0
0.0
estimate
1.28
174
1158
548
4136
1.50
12.34
3.1
2.4
52.0
57.0
u/l
2.40
494
3828
899
7483
1.47
12.25
5.1
4.7
6.9
6.6
mmol/l
2.61
855
7004
256
1624
1.69
12.18
3.2
2.2
182.7
124.1
ug/g
1.08
207
1277
54
188
2.94
11.88
1.7
3.5
1.2
1.5
%
0.29
39
156
305
2056
1.60
11.35
3.6
3.5
0.8
0.8
mmol/l
6.25
280
1926
26
57
4.62
11.20
1.2
1.1
391.7
242.0
iu/ml
0.30
26
57
159
900
1.85
11.17
1.4
1.7
—
—
—
0
0
309
2097
1.59
11.16
2.7
2.5
1.3
1.1
e6/l
0.37
174
1160
368
2607
1.54
10.97
1.4
1.4
2.9
2.4
g/l
4.46
206
1609
996
8548
1.45
10.92
4.7
4.3
178.5
2570.2
e6/l
2.53
13
127
19
32
6.00
10.87
1.8
2.8
—
35.0
—
0
7
413
3011
1.50
10.73
1.2
1.2
2.1
1.4
u/ml
0.23
97
821
246
1599
1.64
10.57
4.5
5.6
1.0
1.0
mmol/l
0.04
228
1476
168
985
1.79
10.52
2.1
2.8
11.0
10.4
g/l
1.05
152
898
285
1930
1.58
10.32
1.8
1.8
—
—
—
0
0
311
2174
1.54
9.74
1.8
1.7
1009.9
1203.4
nmol/l
4.08
240
1647
1345
12365
1.59
9.65
7.0
5.5
41.5
39.4
mmol/mol
11.56
1242
11513
411
3072
1.46
9.21
2.3
2.1
3.1
3.0
mg/l
0.27
351
2608
85
421
2.08
8.82
1.8
1.8
—
—
—
0
0
165
1016
1.70
8.68
2.4
3.0
67.3
66.8
g/l
0.37
155
931
37
126
2.98
8.53
1.5
1.3
45035.3
149769.9
e6/l
0.67
23
88
278
1950
1.52
8.48
2.9
2.7
5.4
2.8
e6/l
1.19
143
1019
612
4970
1.38
8.39
4.7
3.7
—
—
—
0
0
189
1219
1.63
8.31
2.3
2.1
368.4
371.7
nmol/l
0.09
173
1122
99
538
1.90
7.92
1.3
1.2
0.2
1.1
u/ml
—
9
44
270
1913
1.50
7.81
2.2
2.4
12.0
13.5
umol/l
3.02
252
1761
143
884
1.68
7.42
3.9
3.4
4.5
4.5
pmol/l
0.17
132
783
1367
12775
1.52
7.37
17.7
12.0
84.3
81.9
ml/min/173m2
3.78
1171
10524
1497
14311
1.88
7.33
16.8
10.1
26.1
25.7
u/l
0.41
1464
13848
1336
12451
1.47
7.06
5.7
4.9
1.8
2.0
mu/l
1.42
1239
11462
75
388
1.98
6.96
1.5
1.6
0.3
0.2
g/l
0.39
70
372
1009
8991
1.34
6.95
3.8
3.1
54.3
46.3
u/l
1.25
927
8404
428
3379
1.37
6.69
2.8
2.8
1525.7
1040.8
ng/l
1.22
349
2859
1162
10602
1.36
6.68
4.8
4.2
14.9
14.7
pmol/l
0.87
1069
9712
542
4438
1.34
6.66
3.8
3.2
34.2
31.6
u/l
0.40
501
4241
193
1322
1.52
6.52
2.8
4.5
248.5
246.1
u/l
0.04
184
1254
71
373
1.95
6.33
3.0
2.8
—
—
—
0
0
241
1740
1.45
6.28
2.2
2.4
2.5
2.4
g/l
1.97
224
1608
575
4780
1.32
6.27
3.8
3.3
42.2
41.3
ng/l
0.03
368
3119
60
298
2.05
6.26
2.1
2.4
77.4
99.3
ug/min
0.23
30
184
46
206
2.27
6.21
1.2
1.1
12466.0
121.2
iu/ml
—
10
44
194
1349
1.50
6.10
1.8
1.7
—
—
—
0
0
1418
13452
1.53
6.09
5.6
4.4
4.7
4.8
mmol/l
6.23
1327
12526
1448
13807
1.58
5.99
19.2
14.7
139.6
139.8
mmol/l
1.74
1411
13474
1410
13368
1.51
5.98
5.1
4.4
1.4
1.5
mmol/l
13.28
1301
12386
186
1288
1.50
5.97
2.1
2.8
1.8
1.9
%
0.66
166
1156
1435
13666
1.55
5.85
5.7
4.9
2.7
2.8
mmol/l
4.20
1328
12656
82
464
1.81
5.84
2.0
2.5
3.3
3.1
g/l
0.64
66
368
344
2677
1.36
5.79
1.8
1.6
65603257.8
35468414.2
pmol/l
0.24
282
2233
1389
13145
1.47
5.79
5.2
4.4
6.2
5.9
mmol/l
14.42
1264
12054
194
1366
1.48
5.74
1.8
1.7
—
—
—
0
0
223
1615
1.44
5.70
2.1
2.4
19.4
23.2
%
4.22
189
1372
192
1356
1.47
5.59
6.5
8.3
1.4
1.2
mmol/l
0.16
158
1074
154
1039
1.53
5.59
3.5
3.5
2.1
2.0
mmol/l
0.12
126
840
35
146
2.43
5.56
1.1
1.2
64.1
53.6
u/l
0.64
27
101
191
1356
1.46
5.42
6.5
8.3
11.5
12.5
kpa
2.18
183
1304
191
1356
1.46
5.42
6.5
8.3
5.3
5.1
kpa
2.17
184
1304
362
2867
1.34
5.40
1.5
1.5
19.7
21.4
nmol/l
1.15
303
2443
84
491
1.75
5.39
1.9
2.4
4.2
3.7
g/l
2.27
65
360
84
491
1.75
5.39
1.9
2.4
8.0
7.4
g/l
2.31
67
380
84
491
1.75
5.39
1.9
2.4
—
—
—
0
0
1447
13844
1.54
5.33
19.4
14.8
4.0
4.0
mmol/l
3.65
1411
13488
64
346
1.89
5.29
2.0
1.7
—
—
—
0
0
76
435
1.78
5.24
1.8
1.7
—
—
—
0
0
1203
11174
1.32
5.18
24.1
16.0
13.9
13.7
%
7.96
1184
10927
1363
12909
1.41
5.12
5.0
3.9
1.5
1.3
mmol/l
16.23
1253
11892
173
1220
1.47
5.08
2.0
2.2
0.2
0.2
g/l
1.12
159
1153
152
1045
1.50
5.06
3.5
3.5
6.0
5.8
kpa
0.84
146
1012
62
337
1.87
5.05
1.3
1.3
—
—
—
0
0
42
199
2.14
5.01
5.9
5.6
390.7
375.1
umol/l
0.26
33
177
148
1015
1.51
4.99
3.6
3.6
73.6
80.5
ng/l
0.77
127
884
77
450
1.75
4.96
2.0
2.4
10.0
10.2
g/l
0.11
67
391
47
235
2.03
4.88
1.3
1.3
—
—
—
0
0
349
2788
1.32
4.85
4.8
3.9
1.0
1.0
kg/l
0.07
50
395
300
2352
1.34
4.74
1.4
1.5
—
—
—
0
0
27
108
2.53
4.72
1.9
3.4
61.2
56.5
%
0.51
18
75
208
1544
1.40
4.62
1.8
1.8
1.7
1.4
%
4.64
171
1360
67
387
1.76
4.52
2.1
2.4
37.6
38.1
g/l
0.25
62
343
369
2998
1.30
4.51
1.6
1.7
1.1
1.1
mg/l
0.00
289
2274
75
449
1.70
4.47
2.3
2.0
1.6
2.0
ug/l
0.15
68
403
46
237
1.97
4.43
4.2
2.4
16.5
16.3
%
0.14
25
121
146
1024
1.47
4.42
6.3
7.2
9.6
8.9
mmol/l
0.54
139
978
532
4539
1.26
4.37
3.1
3.5
2.4
2.4
mmol/l
0.38
462
4013
159
1143
1.43
4.24
6.9
9.2
122.7
121.2
g/l
0.43
154
1107
176
1289
1.41
4.23
3.7
3.1
—
—
—
0
0
301
2399
1.31
4.22
4.2
3.5
261.8
303.8
ng/l
0.12
216
1755
64
376
1.73
4.10
2.9
3.7
2.1
1.8
ratio
—
10
36
65
385
1.72
4.05
1.7
1.4
227.9
299.8
ug/g
2.14
37
217
44
231
1.93
4.04
1.4
1.4
—
—
—
0
0
146
1047
1.43
3.96
3.8
3.8
1.2
1.2
mmol/l
0.59
126
913
77
481
1.63
3.94
1.9
1.9
—
—
—
0
0
15
48
3.15
3.93
1.2
1.2
—
—
—
0
0
108
736
1.50
3.80
6.5
8.1
25.5
24.6
mmol/l
1.45
102
691
85
1279
0.65
3.80
1.8
1.7
—
—
—
0
0
64
386
1.69
3.76
3.0
3.7
54.5
73.4
mg/l
0.35
55
314
64
386
1.69
3.76
3.0
3.7
26.9
36.5
mg/l
0.64
54
315
19
72
2.66
3.73
1.4
1.6
—
—
—
0
0
19
72
2.66
3.73
1.5
1.6
—
—
—
0
0
102
693
1.50
3.65
6.5
7.6
25.1
25.1
mmol/l
0.05
102
688
17
62
2.76
3.59
1.0
1.2
13.5
10.6
u/l
0.57
12
54
21
87
2.43
3.47
1.4
1.5
—
—
—
0
0
28
553
0.50
3.45
1.5
1.7
3.3
4.0
mg/l
0.23
22
391
100
693
1.47
3.28
1.6
1.6
—
—
—
0
0
1522
14884
1.61
3.25
29.3
19.3
275.0
256.8
e9/l
20.29
1491
14536
118
849
1.42
3.18
3.0
2.8
4.6
4.5
kpa
0.27
111
816
1522
14892
1.60
3.13
29.4
19.3
4.4
4.5
e12/l
3.12
1488
14498
1522
14893
1.60
3.12
29.5
19.4
7.5
6.6
e9/l
59.60
1488
14499
76
503
1.54
3.11
1.3
1.9
1.8
1.6
g/l
1.13
65
440
21
92
2.30
3.10
1.3
1.2
—
—
—
0
0
49
291
1.71
3.09
4.3
2.6
25.5
24.8
mmol/l
0.45
43
260
60
376
1.62
3.09
2.0
1.9
4.4
4.8
iu/l
0.08
20
129
1522
14896
1.59
3.08
29.6
19.4
133.9
134.9
g/l
1.91
1506
14697
42
239
1.78
3.07
2.0
1.7
—
—
—
0
0
60
377
1.61
3.06
1.4
1.2
13.0
11.3
u/ml
—
5
68
21
94
2.25
2.97
1.3
1.2
—
—
—
0
0
33
176
1.89
2.97
1.4
1.5
—
—
—
0
0
159
1217
1.34
2.96
3.1
2.3
32.8
40.6
u/l
0.66
130
1047
19
82
2.33
2.91
1.2
1.1
19.4
15.3
u/l
0.25
19
68
32
170
1.90
2.91
2.4
2.3
48.4
27.8
mg/l
0.62
14
47
105
754
1.42
2.88
3.4
3.2
5.3
5.1
kpa
1.13
97
713
21
96
2.20
2.84
1.6
1.7
—
—
—
0
0
13
47
2.78
2.82
1.1
1.3
—
—
—
0
0
139
1052
1.35
2.80
6.2
7.2
1.3
1.3
mmol/l
0.03
132
1009
12
42
2.87
2.75
1.3
1.1
—
—
—
0
0
66
438
1.53
2.71
1.4
1.7
—
—
—
0
0
40
236
1.71
2.63
1.3
1.5
—
—
—
0
0
36
207
1.76
2.59
1.4
1.5
—
—
—
0
0
99
719
1.40
2.58
3.4
3.2
2.1
1.7
mmol/l
0.42
82
549
33
185
1.80
2.58
1.4
1.5
—
—
—
0
0
49
307
1.62
2.58
1.5
1.6
—
—
—
0
0
132
1005
1.34
2.57
1.2
1.2
89.2
163.7
iu/ml
1.91
40
400
35
200
1.77
2.57
1.2
1.4
30.2
30.8
u/l
0.04
27
166
629
5684
1.18
2.56
3.0
2.7
131.8
114.0
ug/l
0.34
576
5272
42
255
1.66
2.50
3.6
2.1
130.5
130.7
g/l
0.01
34
183
20
95
2.12
2.49
1.6
1.5
5.6
6.7
u/l
0.13
11
47
77
540
1.45
2.44
3.7
3.8
23.6
24.3
mmol/l
1.07
69
484
86
619
1.41
2.38
7.8
10.3
24.2
24.5
mmol/l
0.30
78
590
25
132
1.91
2.36
1.5
1.7
—
—
—
0
0
7
17
4.13
2.36
1.0
1.2
—
—
—
0
0
187
1517
1.26
2.30
14.3
22.0
1.1
1.3
inr
1.60
37
210
12
47
2.57
2.27
2.7
4.2
—
—
—
0
0
42
265
1.60
2.19
1.3
2.0
0.8
0.9
nmol/l
0.09
37
224
30
174
1.74
2.14
1.6
1.6
—
—
—
0
0
36
220
1.65
2.13
1.5
1.7
—
—
—
0
0
49
328
1.51
2.00
3.1
3.3
1.6
1.5
mg/l
0.24
44
308
27
156
1.74
1.97
1.0
1.1
—
—
—
0
0
7
21
3.34
1.96
2.6
1.4
138.7
90.7
ng/l
—
7
21
14
64
2.20
1.94
1.1
1.3
—
—
—
0
0
53
364
1.47
1.93
2.3
2.1
12.2
11.8
mg/l
0.12
45
337
667
6153
1.15
1.92
4.3
3.9
—
—
—
0
0
43
284
1.53
1.88
1.1
1.4
—
—
—
0
0
14
65
2.16
1.88
1.1
1.3
—
—
—
0
0
122
967
1.28
1.84
2.3
2.4
22.6
24.5
au/ml
—
5
49
19
101
1.89
1.81
3.4
2.5
—
—
—
0
0
898
8472
1.14
1.81
3.1
2.9
—
—
—
0
0
93
715
1.32
1.77
1.6
1.5
—
—
—
0
0
15
74
2.04
1.75
1.3
1.4
—
—
—
0
0
178
1488
1.22
1.71
2.9
2.7
7.0
7.8
umol/l
0.28
145
1292
21
118
1.79
1.70
1.5
1.6
—
—
—
0
0
21
118
1.79
1.70
1.5
1.6
—
—
—
0
0
21
118
1.79
1.70
1.5
1.6
—
—
—
0
0
72
540
1.35
1.64
2.7
2.5
1.8
1.2
%
2.70
72
535
52
369
1.42
1.63
1.7
2.5
4.2
3.6
g/l
1.56
47
352
11
49
2.25
1.63
1.5
1.1
102.3
109.9
%
0.27
11
41
36
237
1.53
1.63
1.3
1.3
—
—
—
0
0
36
237
1.53
1.63
1.3
1.3
—
—
—
0
0
44
303
1.47
1.62
1.5
1.6
—
—
—
0
0
14
263
0.53
1.61
1.2
1.4
—
—
—
0
0
10
43
2.33
1.60
1.3
1.8
38.1
52.7
ug/l
—
10
43
13
63
2.07
1.60
1.5
2.0
—
—
—
0
0
67
500
1.36
1.58
3.6
3.4
48.0
49.1
%
0.13
67
491
17
94
1.82
1.47
1.4
1.4
4760.0
159300.0
e6/l
—
7
50
271
2388
1.16
1.46
3.1
3.0
2.5
2.5
mmol/l
4.12
232
2115
9
38
2.38
1.45
1.2
2.3
—
—
—
0
0
7
28
2.51
1.45
1.4
1.6
—
—
—
0
0
18
102
1.77
1.45
1.3
1.1
—
43.4
—
0
5
18
102
1.77
1.45
1.6
2.3
800.0
600.9
ml
—
10
73
26
164
1.60
1.43
1.5
1.5
363.4
315.4
pmol/l
0.26
21
133
13
66
1.98
1.43
1.5
1.8
—
—
—
0
0
13
66
1.98
1.43
1.5
1.8
—
—
—
0
0
13
66
1.98
1.43
1.5
1.8
—
—
—
0
0
13
66
1.98
1.43
1.5
1.8
—
—
—
0
0
17
95
1.80
1.43
1.4
1.1
—
2.3
—
0
6
18
103
1.76
1.41
1.3
1.1
—
38.4
—
0
8
7
29
2.42
1.39
1.0
1.3
—
—
—
0
0
7
29
2.42
1.39
1.0
1.2
—
—
—
0
0
12
223
0.53
1.37
1.6
1.4
—
—
—
0
0
12
223
0.53
1.37
1.6
1.4
—
—
—
0
0
12
223
0.53
1.37
1.6
1.4
—
—
—
0
0
12
222
0.54
1.35
1.6
1.4
—
—
—
0
0
48
352
1.38
1.30
1.7
2.0
125.0
2964.5
u/l
1.80
21
144
139
1169
1.21
1.30
1.6
1.9
—
—
—
0
0
1263
12289
1.14
1.28
20.0
14.0
39.7
39.7
%
0.08
829
9069
127
1061
1.21
1.28
3.1
2.5
64.5
68.3
ml/min/173m2
0.52
50
419
191
1658
1.17
1.26
4.5
4.4
31.3
32.6
%
0.91
148
1127
27
398
0.67
1.24
1.6
1.5
—
—
—
0
0
13
70
1.86
1.24
1.1
1.5
16.7
23.1
umol/l
0.48
13
65
17
100
1.71
1.23
1.3
1.3
17.1
11.7
mmol/l
—
6
22
125
1047
1.21
1.23
1.6
1.8
—
—
—
0
0
14
240
0.58
1.23
1.4
1.5
—
—
—
0
0
24
155
1.56
1.23
1.1
1.7
—
1552.0
—
0
5
137
1605
0.84
1.18
3.0
2.9
0.6
0.7
ug/l
1.31
91
1026
5
20
2.50
1.15
2.4
1.3
—
—
—
0
0
16
95
1.69
1.14
1.3
1.1
—
—
—
0
0
183
1601
1.16
1.11
6.7
6.2
—
—
—
0
0
44
328
1.35
1.11
1.2
1.2
—
—
—
0
0
10
51
1.97
1.11
1.1
1.3
—
—
—
0
0
8
41
1.96
1.09
2.0
1.9
—
—
—
0
0
8
41
1.96
1.09
2.0
1.4
—
—
—
0
0
27
185
1.47
1.08
1.1
1.1
—
—
—
0
0
72
578
1.26
1.07
2.0
2.0
38.7
39.1
u/l
0.06
61
515
25
170
1.48
1.05
1.2
1.5
—
—
—
0
0
19
122
1.56
1.02
3.2
3.5
—
—
—
0
0
14
83
1.69
1.01
1.0
1.2
—
—
—
0
0
23
155
1.49
1.01
1.3
1.3
—
—
—
0
0
50
387
1.30
1.00
1.2
1.2
—
—
—
0
0
11
61
1.81
0.98
1.4
1.7
8.4
7.5
mmol/l
—
5
35
208
1858
1.14
0.96
1.9
2.1
30.7
29.4
s
1.76
201
1803
22
150
1.47
0.93
1.0
1.1
—
—
—
0
0
11
63
1.75
0.90
2.5
2.1
11.0
264.3
ug/min
—
5
9
34
254
1.35
0.88
2.7
2.6
1.7
1.5
mmol/l
0.62
34
245
46
362
1.28
0.85
1.3
1.3
—
—
—
0
0
16
104
1.54
0.84
1.1
1.1
—
—
—
0
0
11
178
0.62
0.83
3.2
2.3
17.1
26.8
u/ml
0.16
11
173
84
712
1.19
0.80
1.0
1.0
—
—
—
0
0
30
225
1.34
0.78
1.1
1.2
1.7
4.4
u/ml
0.96
11
63
16
107
1.50
0.76
1.4
1.5
—
—
—
0
0
28
209
1.35
0.76
1.0
1.1
—
—
—
0
0
337
3139
1.09
0.75
2.5
2.2
—
—
—
0
0
9
53
1.70
0.75
1.2
1.3
—
—
—
0
0
9
53
1.70
0.75
1.2
1.3
—
—
—
0
0
9
53
1.70
0.75
2.2
2.3
—
—
—
0
0
14
91
1.54
0.75
1.9
2.3
1118.4
701.1
e6/l
—
7
38
11
67
1.65
0.75
1.0
1.0
—
—
—
0
0
5
24
2.09
0.74
3.6
1.6
1.1
1.2
mmol/l
—
5
24
19
133
1.43
0.73
1.5
1.7
—
—
—
0
0
8
133
0.60
0.73
1.7
1.5
—
—
—
0
0
58
481
1.21
0.71
2.7
3.5
982.3
2933.4
u/ml
0.43
46
415
12
182
0.66
0.71
1.8
1.5
—
—
—
0
0
31
239
1.30
0.69
2.9
2.7
9.6
7.3
mmol/l
0.81
31
231
49
401
1.23
0.68
1.2
1.1
—
—
—
0
0
47
573
0.81
0.68
1.3
1.5
—
—
—
0
0
9
59
1.53
0.68
1.9
1.2
198.6
416.9
u/l
—
9
53
20
144
1.39
0.68
1.5
1.6
—
—
—
0
0
18
128
1.41
0.65
1.1
1.2
—
—
—
0
0
105
925
1.14
0.65
3.1
2.8
168.0
168.9
ng/l
0.01
99
842
31
393
0.78
0.64
1.2
1.5
114.6
212.3
pmol/l
1.03
31
387
35
278
1.26
0.64
1.6
1.3
10.8
11.8
u/l
0.18
26
219
0
21
0.00
0.60
0.0
5.8
—
68.8
—
0
16
22
166
1.33
0.58
1.2
1.5
—
—
—
0
0
22
166
1.33
0.58
1.2
1.5
—
—
—
0
0
10
64
1.57
0.58
2.4
3.2
—
—
—
0
0
19
140
1.36
0.58
3.7
4.9
18.9
53.6
u/ml
—
5
43
8
53
1.51
0.58
1.0
1.2
—
—
—
0
0
23
298
0.77
0.58
3.0
3.8
15.7
30.4
u/ml
2.34
23
289
28
220
1.28
0.57
1.1
1.2
2.9
6.1
u/ml
1.05
12
81
22
167
1.32
0.57
1.2
1.5
—
—
—
0
0
22
167
1.32
0.57
1.2
1.5
—
—
—
0
0
6
36
1.67
0.56
1.0
1.1
—
—
—
0
0
17
124
1.38
0.55
1.5
1.6
—
—
—
0
0
6
37
1.62
0.55
1.0
1.1
—
—
—
0
0
13
90
1.45
0.55
1.9
2.0
—
—
—
0
0
9
63
1.43
0.52
2.6
2.8
856.2
995.5
u/ml
—
9
63
6
98
0.61
0.52
1.2
1.5
13.4
11.8
umol/l
—
6
92
6
40
1.50
0.51
1.0
1.2
—
—
—
0
0
6
40
1.50
0.51
1.0
1.2
—
—
—
0
0
42
352
1.20
0.50
1.0
1.1
—
—
—
0
0
6
41
1.47
0.50
1.0
1.9
—
—
—
0
0
30
243
1.24
0.49
1.6
1.7
48.9
40.2
nmol/l
0.57
30
233
26
207
1.26
0.49
2.1
1.6
—
—
—
0
0
12
84
1.43
0.49
1.1
1.1
1.1
1.0
ratio
—
6
32
7
110
0.63
0.48
1.3
1.5
1.0
1.0
g/l
—
7
110
45
383
1.18
0.47
2.6
1.6
256.8
309.2
mu/l
1.00
40
344
7
49
1.43
0.46
1.1
2.3
—
55726.6
—
0
8
47
403
1.17
0.45
1.2
1.1
—
—
—
0
0
5
31
1.61
0.43
1.0
1.2
—
—
—
0
0
5
31
1.61
0.43
1.0
1.0
—
—
—
0
0
27
221
1.23
0.42
1.1
1.1
—
—
—
0
0
5
32
1.56
0.42
1.2
1.0
—
—
—
0
0
25
203
1.24
0.42
1.1
1.1
—
—
—
0
0
206
2189
0.93
0.41
3.9
4.1
20.7
21.0
%
0.07
90
1003
0
16
0.00
0.41
0.0
1.6
—
—
—
0
0
11
79
1.40
0.40
1.0
1.1
—
—
—
0
0
248
2614
0.94
0.39
1.5
1.4
—
—
—
0
0
21
169
1.25
0.38
1.2
1.5
—
—
—
0
0
38
441
0.86
0.38
2.7
1.8
—
—
—
0
0
10
136
0.73
0.37
1.0
1.1
—
—
—
0
0
57
506
1.13
0.37
1.2
1.7
—
—
—
0
0
15
116
1.30
0.37
1.1
1.2
0.2
0.8
u/ml
—
7
47
13
99
1.32
0.35
1.2
1.1
—
—
—
0
0
13
99
1.32
0.35
1.2
1.1
—
—
—
0
0
71
643
1.11
0.34
1.4
1.8
—
—
—
0
0
13
100
1.30
0.33
1.2
1.1
—
—
—
0
0
13
100
1.30
0.33
1.2
1.1
—
—
—
0
0
13
100
1.30
0.33
1.2
1.1
—
—
—
0
0
6
90
0.67
0.32
1.2
1.3
—
—
—
0
0
13
165
0.79
0.32
1.4
1.4
—
—
—
0
0
106
986
1.08
0.30
2.4
2.3
3.4
6.9
ug/l
6.62
88
876
23
271
0.85
0.29
5.7
3.5
17.8
23.2
mg/l
0.53
11
168
8
62
1.29
0.28
1.3
1.1
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
40
357
1.12
0.26
2.3
3.0
0.4
0.4
u/ml
0.06
29
199
13
105
1.24
0.24
1.0
1.0
—
—
—
0
0
10
78
1.28
0.24
1.0
1.1
—
—
—
0
0
6
83
0.72
0.24
1.5
1.7
—
—
—
0
0
43
390
1.11
0.23
1.5
1.3
157.5
228.5
miu/ml
0.65
16
186
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
79
1.27
0.22
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
5.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
2.1
—
—
—
0
0
13
108
1.21
0.20
1.5
2.0
1.0
2.2
u/field
—
5
51
19
218
0.87
0.19
1.1
1.1
—
9.4
—
0
13
19
217
0.87
0.18
1.2
1.2
378.7
280.3
u/ml
—
10
131
7
62
1.13
0.17
1.0
1.1
—
—
—
0
0
141
1359
1.04
0.16
2.6
4.2
58.1
22.1
ug/l
0.43
112
1107
15
130
1.16
0.15
1.4
1.2
—
—
—
0
0
28
307
0.91
0.15
1.3
1.5
666.2
1800.9
e6/l
0.49
22
247
28
307
0.91
0.15
1.2
1.4
3.4
25.1
e6/l
1.28
22
235
19
169
1.13
0.14
2.1
1.9
153.3
207.6
pmol/l
1.86
19
158
21
230
0.91
0.11
1.2
1.2
—
—
—
0
0
29
270
1.08
0.10
1.2
1.6
—
—
—
0
0
11
96
1.15
0.10
1.0
1.1
—
—
—
0
0
14
156
0.90
0.10
1.9
1.7
—
—
—
0
0
5
45
1.11
0.09
1.2
2.2
16.8
27.6
%
—
5
40
6
54
1.11
0.09
1.0
1.1
1637.7
1762.9
miu/ml
—
6
54
6
55
1.09
0.09
3.2
1.7
—
—
—
0
0
7
64
1.09
0.08
1.0
1.1
—
—
—
0
0
7
66
1.06
0.08
4.3
6.3
—
71.4
u/ml
—
0
17
9
85
1.06
0.07
1.4
1.8
—
—
—
0
0
9
85
1.06
0.07
1.1
1.1
—
—
—
0
0
62
640
0.97
0.07
2.2
2.2
10.7
12.4
nmol/l
0.88
54
577
60
581
1.03
0.06
1.5
1.4
—
—
—
0
0
66
643
1.03
0.05
1.5
1.3
35.2
34.8
iu/l
0.04
52
547
23
218
1.06
0.05
1.5
1.4
68.8
132.9
u/ml
—
6
43
25
261
0.96
0.04
1.7
1.6
—
—
—
0
0
271
2702
1.00
0.01
4.3
4.7
1.9
2.6
ug/l
1.35
234
2434
72
726
0.99
0.00
1.5
1.4
—
—
—
0
0
20
204
0.98
0.00
1.7
1.5
0.2
0.3
nmol/l
1.36
12
149
12
122
0.98
0.00
1.2
1.3
—
—
—
0
0
12
119
1.01
0.00
2.3
2.2
—
—
—
0
0
24
243
0.99
0.00
1.1
1.1
0.9
1.1
u/ml
0.17
12
99
13
135
0.96
0.00
1.0
1.0
0.0
0.5
u/ml
—
5
36
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
0.00
2.4
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
2.4
—
0
5
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
5
54
0.93
0.00
1.4
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
37.1
—
0
7
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
1.4
1.9
—
—
—
0
0
5
54
0.93
0.00
1.4
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
22.2
—
0
7
7
77
0.91
0.00
1.3
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
5.5
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
402.8
—
0
6
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
8.8
—
0
7
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_PSORI_PUSTUPALM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PSORI_PUSTUPALM | 1.24 [1.1, 1.4] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.688 |
During the follow-up period (1.1.1998 — 31.12.2019), 556 out of 5683 females with L12_PSORI_PUSTUPALM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_PSORI_PUSTUPALM | 1.432 [1.25, 1.64] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 387 out of 2303 males with L12_PSORI_PUSTUPALM died.
Mortality risk
Mortality risk for people of age
years, who have L12_PSORI_PUSTUPALM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.121% | 0.28% |
| 5 | 0.713% | 1.631% |
| 10 | 1.761% | 4.463% |
| 15 | 3.768% | 8.079% |
| 20 | 7.043% | 14.014% |
Relationships between endpoints
↥Index endpoint: L12_PSORI_PUSTUPALM – Pustulosis palmaris et plantaris
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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