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IBD patients in KELA-register

K11_KELAIBD

inflammatory bowel disease: A spectrum of small and large bowel inflammatory diseases of unknown etiology. It includes Crohn's disease, ulcerative colitis, and colitis of indeterminate type.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

KELA reimbursements: KELA codes 208|209

1 out of 7 registries used, show all original rules.

9363

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Check minimum number of events None

9363

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Include endpoints None

9363

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Remove individuals based on genotype QC

9083

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K11_KELAIBD

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to IBD patients in KELA-register based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 9083 4742 4341
Unadjusted prevalence (%) 2.20 2.06 2.39
Mean age at first event (years) 40.39 38.19 42.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.17 [0.69, 1.98] 5.7e-1 471
15 years 0.01 0.87 [0.54, 1.42] 5.8e-1 187
5 years 0.00 1.60 [1.06, 2.42] 2.5e-2 88
1 year 0.00 2.77 [1.67, 4.59] 7.4e-5 27

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_KELAIBD – IBD patients in KELA-register
GWS hits: 68

Survival analyses between endpoints

Plot

before IBD patients in KELA-register
after IBD patients in KELA-register

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Drugs most likely to be purchased after IBD patients in KELA-register

Endpoint not on priority list, no data to show.