No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
365 |
4. Check minimum number of eventsNone |
365 |
5. Include endpointsNone |
365 |
6. Filter based on genotype QC (FinnGen only) |
365 |
Control definitions (FinnGen only)
- Control exclude
- K11_OESSTODUO
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K20-K31
- Name in latin
- Ulcus pepticum loco non specificato
Similar endpoints
↥List of similar endpoints to
Peptic ulcer
based on the number of shared cases.
Similar with more cases:
- Gastroduodenal ulcer
- Diseases of oesophagus, stomach and duodenum
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4182 | 1927 | 2191 |
| Only index persons | 3048 | 1448 | 1600 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 63.74 | 68.52 | 59.49 |
| Only index persons | 61.57 | 66.17 | 57.40 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 365 | 172 | 193 |
| Unadjusted period prevalence (%) | 0.07 | 0.06 | 0.09 |
| Median age at first event (years) | 59.66 | 56.12 | 62.81 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 329
- Matched controls
- 3289
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K27.9
ICD-10 Finland
Peptic ulcer, site unspecified, unspecified as acute or chronic, without haemorrhage or perforation
+∞
126.4
113
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
15.8
103.8
208
323
K27.0
ICD-10 Finland
Peptic ulcer, site unspecified, acute with haemorrhage
+∞
87.5
80
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
25.8
30.9
43
19
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
4.2
30.5
159
603
K92.1
ICD-10 Finland
Melaena
12.1
28.0
52
50
UJD02
NOMESCO Finland
Gastroscopy
17.3
27.8
44
29
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
+∞
27.5
26
*
K27.1
ICD-10 Finland
Peptic ulcer, site unspecified, acute with perforation
+∞
24.3
23
*
K27.4
ICD-10 Finland
Peptic ulcer, site unspecified, chronic or unspecified with haemorrhage
+∞
23.2
22
*
K27.3
ICD-10 Finland
Peptic ulcer, site unspecified, acute without haemorrhage or perforation
+∞
23.2
22
*
53399
ICD-8 Finland
Peptic ulcer, site unspecified, Without mention of perforation
+∞
21.1
20
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
15.6
20.9
34
24
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
+∞
20.0
19
*
A02BC01
ATC
omeprazole; systemic
3.3
19.7
124
503
A02BC02
ATC
pantoprazole; systemic
3.1
19.6
235
1478
A02BC03
ATC
lansoprazole; oral
3.3
19.6
124
508
K29.7
ICD-10 Finland
Gastritis, unspecified
46.9
18.5
22
5
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
7.6
18.0
43
64
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
+∞
17.9
17
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.6
17.6
65
166
K29.3
ICD-10 Finland
Chronic superficial gastritis
63.2
15.9
18
*
D64.9
ICD-10 Finland
Anaemia, unspecified
4.5
15.5
58
149
UJF32
NOMESCO Finland
Coloscopy
3.0
15.2
108
463
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
14.9
64
188
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.6
14.6
71
231
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
+∞
13.6
13
*
K30
ICD-10 Finland
Functional dyspepsia
6.3
13.5
36
63
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
5.3
12.9
40
84
JDA60
NOMESCO Finland
Closure of perforated ulcer of stomach
+∞
12.6
12
*
K27.7
ICD-10 Finland
Peptic ulcer, site unspecified, chronic without haemorrhage or perforation
+∞
12.6
12
*
A02BA02
ATC
ranitidine; systemic
2.9
12.3
83
339
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
31.3
11.7
15
5
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
+∞
10.5
10
*
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
+∞
10.5
10
*
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
+∞
10.5
10
*
K92.0
ICD-10 Finland
Haematemesis
8.9
10.2
21
25
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
7.4
10.0
23
33
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
6.9
9.9
24
37
P01AB01
ATC
metronidazole; oral, rectal
2.2
9.5
128
744
C03CA01
ATC
furosemide; systemic
2.2
9.4
129
753
K26.4
ICD-10 Finland
Duodenal ulcer, chronic or unspecified with haemorrhage
+∞
9.4
9
*
K27.5
ICD-10 Finland
Peptic ulcer, site unspecified, chronic or unspecified with perforation
+∞
9.4
9
*
R07.4
ICD-10 Finland
Chest pain, unspecified
2.4
9.3
94
475
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.6
9.3
32
76
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.7
9.2
68
288
R50.9
ICD-10 Finland
Fever, unspecified
2.9
9.1
58
225
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.8
9.0
64
265
A02BC05
ATC
esomeprazole; systemic
2.1
8.9
124
723
JN3AD
NOMESCO Finland
Abdominal CT examination
4.0
8.7
34
91
R11
ICD-10 Finland
Nausea and vomiting
3.8
8.5
36
104
N02AX02
ATC
tramadol; systemic, rectal
2.0
8.5
144
908
53390
ICD-8 Finland
Peptic ulcer, site unspecified, Perforatione non indicata, cum haemorrhagia
+∞
8.4
8
*
K25.1
ICD-10 Finland
Gastric ulcer, Acute with perforation
+∞
8.4
8
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
8.1
67
303
N05BA01
ATC
diazepam; systemic, rectal
2.8
7.6
51
204
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.9
7.6
47
178
A03FA02
ATC
cisapride; oral, rectal
3.5
7.5
34
104
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
81.8
7.4
8
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.1
7.4
41
143
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
7.4
100
571
K27.2
ICD-10 Finland
Peptic ulcer, site unspecified, acute with both haemorrhage and perforation
+∞
7.3
7
*
K26.3
ICD-10 Finland
Duodenal ulcer, acute without haemorrhage or perforation
+∞
7.3
7
*
N03AX16
ATC
pregabalin; oral
2.2
7.2
76
388
E66.8
ICD-10 Finland
Other obesity
4.5
7.2
24
56
A02BD03
ATC
lansoprazole, amoxicillin and metronidazole; systemic
3.3
6.8
33
108
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
6.7
26
70
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
6.7
6.7
16
25
K29.4
ICD-10 Finland
Chronic atrophic gastritis
23.0
6.7
9
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
6.6
77
408
C07AB07
ATC
bisoprolol; oral
1.8
6.6
162
1136
R53
ICD-10 Finland
Malaise and fatigue
2.2
6.6
71
363
A06AD11
ATC
lactulose; oral
2.3
6.6
63
307
E66.01
ICD-10 Finland
Obesity due to excess calories
3.5
6.6
29
88
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.8
6.5
41
158
N05CF01
ATC
zopiclone; oral
1.9
6.4
111
689
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
9.5
6.3
12
13
JAH00
NOMESCO Finland
Laparotomy
5.0
6.3
19
40
K27
ICD-10 Finland
Peptic ulcer, site unspecified
+∞
6.3
6
*
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
+∞
6.3
6
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.5
6.1
48
210
E66.00
ICD-10 Finland
Metabolic syndrome
3.9
6.0
23
62
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
175
815
3.20
26.27
3.7
2.4
52.4
56.3
u/l
0.89
162
749
130
683
2.40
13.50
3.6
2.0
3.5
3.3
mg/l
0.40
119
576
214
1414
2.24
12.60
9.3
6.2
12.2
11.4
umol/l
0.29
203
1336
53
187
3.14
11.91
1.9
1.6
—
—
—
0
0
102
537
2.25
10.13
1.9
1.7
1233.4
1200.9
nmol/l
0.11
82
389
86
421
2.36
10.13
3.1
2.3
11.0
12.4
umol/l
1.19
79
383
90
459
2.27
9.59
2.3
1.8
—
—
—
0
0
76
365
2.37
9.29
3.2
2.4
20.1
22.1
%
0.50
67
320
68
314
2.43
9.05
2.4
1.7
—
—
—
0
0
166
1088
1.96
8.97
4.9
3.7
35.7
49.4
ng/l
0.79
128
792
181
1239
1.91
8.44
6.2
4.0
—
—
—
0
0
51
217
2.57
8.04
7.9
7.1
11.1
10.3
mmol/l
0.31
51
205
172
1174
1.88
7.95
7.8
4.3
33.4
35.2
g/l
3.39
165
1089
154
1019
1.88
7.80
4.1
3.2
—
—
—
0
0
80
430
2.10
7.32
1.9
1.8
31.1
29.1
s
2.00
80
417
65
322
2.24
7.30
2.4
1.7
—
—
—
0
0
60
289
2.29
7.20
3.3
2.7
9.8
8.6
umol/l
0.19
54
257
160
1093
1.83
7.17
4.9
2.5
128.2
141.7
ug/l
0.34
154
993
126
805
1.86
6.97
2.3
2.0
267.1
254.2
u/l
0.05
119
760
17
40
4.41
6.82
1.3
1.6
—
—
—
0
0
20
55
3.79
6.56
1.5
1.4
260.6
271.8
ug/g
0.07
11
26
24
75
3.35
6.54
1.4
1.3
—
—
—
0
0
52
258
2.18
5.79
6.1
3.5
1.1
2.1
mmol/l
0.88
41
202
52
259
2.17
5.73
6.1
3.5
5.8
5.8
kpa
0.03
52
251
59
309
2.08
5.72
7.4
6.4
0.4
1.4
mmol/l
0.99
49
242
120
797
1.75
5.63
3.9
3.1
0.5
0.4
e6/l
0.26
101
602
209
1613
1.69
5.63
6.7
4.3
7.3
6.7
mmol/l
2.18
203
1513
227
1794
1.70
5.57
6.8
4.4
47.0
2438.2
e6/l
—
9
36
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
23
78
3.08
5.52
2.5
2.1
0.3
0.4
u/ml
0.54
16
33
200
1534
1.67
5.45
11.5
8.7
4.7
4.2
e9/l
1.75
187
1351
85
515
1.85
5.39
1.4
1.2
6.0
1.5
u/ml
0.78
34
141
17
48
3.66
5.39
1.4
1.5
—
—
—
0
0
256
2104
1.72
5.30
12.3
7.1
90.1
77.8
u/l
2.56
246
1956
36
161
2.37
5.10
2.8
4.0
1.2
2.1
mmol/l
0.57
27
115
152
1102
1.65
5.04
2.7
2.0
85.3
94.2
pmol/l
1.91
102
552
45
223
2.16
5.02
5.2
2.6
4.4
4.3
kpa
0.10
45
214
22
77
2.98
5.01
1.8
1.5
—
—
—
0
0
180
1373
1.61
4.80
9.3
6.1
1.2
1.2
mmol/l
0.55
153
1148
101
665
1.72
4.79
2.0
1.6
19.6
20.7
nmol/l
0.34
92
555
43
214
2.14
4.75
3.2
2.7
277.1
247.3
ng/l
0.11
36
195
122
857
1.64
4.48
4.4
4.0
4.5
10.9
mg/mmol
2.06
87
525
14
40
3.60
4.37
1.4
1.6
—
—
—
0
0
14
41
3.51
4.22
1.1
1.3
—
—
—
0
0
21
81
2.69
4.05
1.4
1.5
—
—
—
0
0
165
1269
1.55
4.03
8.8
5.3
1.2
1.2
mmol/l
0.98
157
1125
16
53
3.11
4.01
1.7
1.3
—
—
—
0
0
208
1685
1.54
4.00
4.4
2.8
78.5
50.1
u/l
2.19
196
1568
83
545
1.68
3.91
2.1
1.6
1.2
1.2
mg/l
0.11
70
429
34
170
2.10
3.73
1.8
1.4
—
—
—
0
0
12
35
3.51
3.65
1.3
1.6
—
—
—
0
0
11
31
3.63
3.50
1.5
1.2
—
—
—
0
0
91
637
1.57
3.27
3.7
2.3
—
—
—
0
0
17
66
2.65
3.26
1.1
1.5
—
—
—
0
0
116
861
1.51
3.19
3.3
3.1
1848.6
1608.8
ng/l
0.20
101
738
17
68
2.57
3.08
1.1
1.5
—
—
—
0
0
37
207
1.88
3.00
4.8
3.7
82.9
83.3
ng/l
0.01
31
177
121
917
1.48
2.97
4.0
3.3
2.3
2.4
mmol/l
0.49
101
804
85
600
1.54
2.92
2.0
1.8
105797471.4
441.3
pmol/l
0.49
69
485
132
1021
1.46
2.91
6.1
3.9
—
—
—
0
0
161
1294
1.44
2.89
5.7
3.7
0.0
0.0
estimate
0.00
39
255
32
174
1.92
2.83
5.6
2.9
120.1
126.6
g/l
0.80
32
169
161
1298
1.43
2.83
7.7
5.0
0.0
0.0
estimate
0.00
37
248
162
1313
1.42
2.74
5.7
3.7
0.0
0.0
estimate
0.00
37
240
15
60
2.56
2.73
1.6
1.4
—
—
—
0
0
100
743
1.48
2.68
5.7
3.9
0.0
0.0
estimate
0.00
36
243
93
683
1.48
2.64
3.2
2.7
4132.2
7932.6
umol/l
0.42
78
586
13
50
2.66
2.56
1.0
1.3
—
—
—
0
0
10
33
3.09
2.54
1.1
1.7
—
—
—
0
0
76
540
1.51
2.52
4.4
3.4
695.4
245.3
ng/l
0.33
59
431
10
34
3.00
2.43
1.4
1.5
—
—
—
0
0
10
34
3.00
2.43
1.4
1.5
—
—
—
0
0
10
34
3.00
2.43
1.4
1.5
—
—
—
0
0
10
34
3.00
2.43
1.4
1.5
—
—
—
0
0
5
8
6.32
2.38
1.0
3.1
113.2
82.7
%
—
5
8
47
304
1.63
2.34
3.5
4.2
3.3
21.4
ug/l
0.72
42
253
10
35
2.91
2.32
1.4
1.5
—
—
—
0
0
10
35
2.91
2.32
1.1
1.7
—
—
—
0
0
6
13
4.67
2.28
1.0
1.4
—
—
—
0
0
7
18
3.94
2.26
1.6
1.5
—
—
—
0
0
14
60
2.39
2.24
2.4
2.5
14.8
15.6
%
—
8
29
13
54
2.46
2.22
1.1
1.5
—
—
—
0
0
12
48
2.55
2.20
2.8
1.7
4415.6
359.4
u/l
—
5
8
12
48
2.55
2.20
2.6
2.9
5.9
4.6
e9/l
0.54
12
48
8
24
3.38
2.19
1.9
2.4
—
—
—
0
0
13
55
2.41
2.14
1.4
1.3
—
—
—
0
0
13
55
2.41
2.14
1.4
1.3
—
—
—
0
0
66
472
1.49
2.12
3.4
2.8
1.1
1.1
e6/l
0.06
42
280
56
388
1.52
2.09
26.4
25.0
1.4
1.3
inr
—
9
50
5
10
5.05
2.07
3.2
1.5
18.4
31.0
umol/l
—
5
10
131
1063
1.36
2.07
3.2
2.1
72.1
77.7
nmol/l
1.40
120
933
78
580
1.44
2.06
6.5
4.2
1.0
1.0
kg/l
0.78
16
77
27
156
1.79
2.02
5.1
2.7
0.6
0.2
e6/l
0.67
27
151
12
51
2.40
1.97
2.7
3.2
62.8
58.4
%
0.44
12
51
11
45
2.49
1.94
1.1
1.4
—
—
—
0
0
45
302
1.56
1.94
4.6
3.4
—
—
—
0
0
9
33
2.77
1.94
1.4
1.5
—
—
—
0
0
10
40
2.54
1.85
1.2
1.2
—
—
—
0
0
18
95
1.94
1.78
2.1
2.5
—
—
—
0
0
6
18
3.37
1.75
1.0
1.1
—
—
—
0
0
15
76
2.01
1.66
1.7
2.6
33.3
96.7
ug/min
—
8
46
7
26
2.72
1.58
1.0
1.3
—
—
—
0
0
27
169
1.64
1.57
2.7
1.7
—
—
—
0
0
59
440
1.41
1.54
3.4
3.0
1.3
1.8
e6/l
0.47
35
249
15
80
1.91
1.47
1.8
1.3
—
—
—
0
0
9
38
2.40
1.46
1.2
1.1
—
—
—
0
0
7
28
2.53
1.46
1.7
1.3
—
—
—
0
0
10
199
0.49
1.45
1.6
1.6
—
—
—
0
0
222
2007
1.27
1.42
5.3
3.8
16.4
13.0
mm/h
2.04
208
1815
19
111
1.75
1.42
2.7
1.7
—
—
—
0
0
19
111
1.75
1.42
2.7
1.7
3.7
3.6
g/l
0.18
14
80
7
29
2.44
1.40
1.1
1.6
—
—
—
0
0
7
29
2.44
1.40
1.1
1.6
—
—
—
0
0
7
29
2.44
1.40
1.1
1.6
—
—
—
0
0
20
121
1.69
1.33
1.1
1.0
—
—
—
0
0
21
129
1.67
1.33
1.2
1.1
108.4
169.4
iu/ml
—
9
48
37
261
1.46
1.31
1.8
2.0
1.6
1.5
%
0.39
30
228
8
34
2.38
1.30
1.1
1.4
—
—
—
0
0
68
537
1.33
1.26
4.2
2.9
2.4
2.5
mmol/l
0.24
56
487
6
25
2.42
1.25
1.8
1.3
31.8
18.0
u/l
—
6
19
5
20
2.52
1.15
1.2
1.5
—
—
—
0
0
5
22
2.29
1.03
1.2
1.1
—
—
—
0
0
13
77
1.71
0.96
1.2
1.2
—
—
—
0
0
13
77
1.71
0.96
1.2
1.2
—
—
—
0
0
29
209
1.42
0.96
5.4
2.6
62.5
62.3
ml/min/173m2
0.01
11
84
16
101
1.61
0.95
6.4
3.9
3.9
4.0
mmol/l
0.15
16
90
50
395
1.31
0.94
1.5
1.5
—
—
—
0
0
12
71
1.71
0.90
2.2
1.5
—
—
—
0
0
6
31
1.95
0.84
1.3
1.4
—
—
—
0
0
169
1544
1.18
0.80
3.3
2.7
—
—
—
0
0
9
54
1.68
0.75
2.0
1.4
—
—
—
0
0
213
1990
1.17
0.75
4.4
3.7
14.9
14.9
pmol/l
0.02
198
1768
7
40
1.76
0.71
1.0
1.0
—
—
—
0
0
7
43
1.64
0.67
1.7
1.4
—
—
—
0
0
5
28
1.80
0.66
2.2
1.9
—
—
—
0
0
48
398
1.24
0.65
1.2
1.3
1.5
14.0
u/ml
2.91
18
165
16
112
1.45
0.64
1.6
1.8
—
—
—
0
0
8
51
1.58
0.61
1.0
1.1
0.9
0.9
nmol/l
—
8
44
8
52
1.55
0.60
1.9
1.3
—
—
—
0
0
10
65
1.55
0.56
1.2
1.1
—
13.1
—
0
8
262
2717
0.87
0.53
5.7
4.9
2.5
2.7
mmol/l
2.38
247
2457
10
66
1.53
0.53
1.2
1.2
—
—
—
0
0
17
127
1.35
0.50
1.4
1.4
—
—
—
0
0
281
2719
1.14
0.48
31.0
14.2
28.8
25.0
mg/l
1.09
253
2134
7
48
1.47
0.47
2.0
2.0
—
—
—
0
0
5
31
1.62
0.43
1.6
1.0
—
—
—
0
0
257
2654
0.89
0.43
5.2
4.4
4.4
4.6
mmol/l
1.52
243
2410
5
32
1.57
0.42
1.4
1.2
—
—
—
0
0
5
32
1.57
0.42
4.4
4.5
—
—
—
0
0
8
57
1.41
0.42
1.4
1.1
—
—
—
0
0
255
2633
0.89
0.41
5.2
4.4
1.4
1.5
mmol/l
2.26
239
2378
5
33
1.52
0.41
1.2
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
1.1
—
0
13
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
9
68
1.33
0.38
1.1
1.2
—
—
—
0
0
14
107
1.32
0.37
1.7
1.6
—
—
—
0
0
249
2568
0.90
0.37
26.1
13.8
79.4
78.3
ml/min/173m2
0.29
224
2111
5
37
1.36
0.37
1.6
1.6
—
—
—
0
0
256
2635
0.90
0.36
5.2
4.5
6.3
6.0
mmol/l
1.62
239
2360
64
703
0.89
0.33
2.0
1.6
1.7
1.3
mmol/l
1.27
55
576
75
811
0.91
0.30
4.8
4.4
19.1
21.6
%
0.88
35
413
95
1014
0.91
0.29
6.3
5.0
3.0
3.0
ug/l
0.02
86
891
54
592
0.90
0.28
2.8
2.9
0.6
0.8
ug/l
1.37
41
386
236
2424
0.92
0.27
31.2
14.9
37.4
39.7
%
2.53
151
1678
11
86
1.29
0.26
1.5
2.2
—
—
—
0
0
17
144
1.19
0.22
1.2
1.3
—
42.6
—
0
11
0
11
0.00
0.21
0.0
6.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
3.5
—
—
—
0
0
0
13
0.00
0.21
0.0
3.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
8
69
1.16
0.16
1.0
1.3
—
—
—
0
0
46
431
1.08
0.14
1.2
1.2
51.6
40.0
iu/ml
0.20
14
141
256
2529
1.04
0.10
7.5
5.9
42.0
40.2
mmol/mol
1.57
240
2318
10
88
1.14
0.08
1.7
1.6
—
—
—
0
0
252
2544
0.97
0.08
4.8
3.9
1.4
1.3
mmol/l
1.65
237
2290
7
68
1.03
0.08
1.6
1.5
—
—
—
0
0
247
2456
1.02
0.03
5.4
4.4
1.8
2.0
mu/l
1.18
230
2189
37
360
1.03
0.03
12.6
7.6
—
—
—
0
0
33
323
1.02
0.01
1.5
1.4
—
—
—
0
0
21
205
1.03
0.00
1.1
2.1
—
—
—
0
0
22
220
1.00
0.00
1.1
2.3
—
—
—
0
0
13
126
1.03
0.00
1.9
3.3
4.4
4.4
pmol/l
0.08
13
111
12
117
1.03
0.00
1.2
2.2
40.6
41.6
u/l
0.08
12
97
11
105
1.05
0.00
1.9
2.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
5
55
0.91
0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
9.9
—
0
9
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
16.2
—
0
7
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_PULC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PULC | 1.855 [1.57, 2.19] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.207 |
During the follow-up period (1.1.1998 — 31.12.2019), 586 out of 1363 females with K11_PULC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PULC | 2.396 [1.99, 2.88] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 608 out of 1406 males with K11_PULC died.
Mortality risk
Mortality risk for people of age
years, who have K11_PULC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.215% | 0.419% |
| 5 | 1.024% | 2.613% |
| 10 | 2.649% | 6.388% |
| 15 | 4.898% | 11.583% |
| 20 | 8.644% | 19.041% |
Relationships between endpoints
↥Index endpoint: K11_PULC – Peptic ulcer
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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